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Gene: Kcnj2 (potassium inwardly-rectifying channel, subfamily J, member 2) Mus musculus
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Symbol: Kcnj2
Name: potassium inwardly-rectifying channel, subfamily J, member 2
Description: Exhibits identical protein binding activity. Involved in cardiac muscle cell action potential and magnesium ion transport. Predicted to localize to several cellular components, including T-tubule; endoplasmic reticulum; and intercalated disc. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inward rectifier K(+) channel Kir2.1; inward rectifier potassium channel 2; IRK-1; IRK1; Kcnf1; Kir2.1; potassium channel, inwardly rectifying subfamily J member 2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl11111,066,164 - 111,076,821 (+)EnsemblGRCm38mm10GRCm38
GRCm3811111,066,164 - 111,076,825 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711110,927,478 - 110,938,139 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611110,882,254 - 110,891,741 (+)NCBImm8
Celera11122,816,654 - 122,827,315 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1175.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Kcnj2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62261
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.