Fasn (fatty acid synthase) - Rat Genome Database
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Gene: Fasn (fatty acid synthase) Mus musculus
Analyze
Symbol: Fasn
Name: fatty acid synthase
RGD ID: 1615200
MGI Page MGI
Description: Exhibits fatty acid synthase activity. Involved in several processes, including epithelial cell development; ether lipid biosynthetic process; and myeloid leukocyte differentiation. Localizes to glycogen granule. Is expressed in several structures, including adipose tissue; alimentary system; nervous system; sensory organ; and skeleton. Orthologous to human FASN (fatty acid synthase); PARTICIPATES IN fatty acid biosynthetic pathway; insulin signaling pathway; INTERACTS WITH (+)-catechin; (RS)-coclaurine; (RS)-norcoclaurine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A630082H08Rik; F; FAS; type I Fatty Acid Synthase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,696,784 - 120,715,992 (-)NCBIGRCm39mm39
GRCm3811120,805,958 - 120,825,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,805,846 - 120,824,547 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,667,272 - 120,685,861 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611120,623,167 - 120,640,332 (-)NCBImm8
Celera11132,542,449 - 132,561,038 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R)-mevalonic acid  (ISO)
(RS)-coclaurine  (EXP)
(RS)-norcoclaurine  (EXP)
(S)-coclaurine  (EXP)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dichloropropan-2-ol  (EXP,ISO)
1-(3-(trifluoromethyl)phenyl)piperazine  (ISO)
1-\{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl\}-1H-imidazole  (ISO)
1-benzylpiperazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2,5-hexanedione  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3H-1,2-dithiole-3-thione  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (EXP)
4-tert-Octylphenol  (ISO)
5-(2-chloroethyl)-4-methylthiazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
7,12-dimethyltetraphene  (ISO)
8'-apo-beta,psi-caroten-8'-al  (ISO)
9-cis-retinoic acid  (ISO)
acarbose  (ISO)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
alcohol  (EXP)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
alliin  (ISO)
allopurinol  (ISO)
alpha-linolenic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP,ISO)
andrographolide  (EXP)
apigenin  (EXP)
arachidonic acid  (EXP)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atorvastatin calcium  (ISO)
ATP  (ISO)
atrazine  (ISO)
avobenzone  (ISO)
azoxystrobin  (EXP)
baicalein  (EXP)
bathocuproine disulfonic acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
Benzyl parahydroxybenzoate  (EXP,ISO)
benzylpenicillin  (EXP)
beta-D-glucosamine  (ISO)
beta-hexachlorocyclohexane  (EXP,ISO)
beta-naphthoflavone  (ISO)
betulin  (ISO)
bexarotene  (ISO)
bezafibrate  (EXP,ISO)
bifenthrin  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
boric acid  (EXP)
bromobenzene  (ISO)
buspirone  (ISO)
buta-1,3-diene  (EXP)
Butylbenzyl phthalate  (EXP)
Butylparaben  (EXP,ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP,ISO)
carvedilol  (ISO)
celecoxib  (EXP)
cerulenin  (EXP,ISO)
chenodeoxycholic acid  (EXP)
chitosan  (ISO)
chloroethene  (EXP)
chlorogenic acid  (EXP)
chlorohydrocarbon  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
choline  (EXP,ISO)
ciguatoxin CTX1B  (EXP)
cis-caffeic acid  (EXP,ISO)
cisplatin  (ISO)
clobetasol  (EXP)
clofibrate  (EXP,ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
cortisol  (ISO)
coumarin  (ISO)
crizotinib  (ISO)
curcumin  (EXP,ISO)
cyanocob(III)alamin  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cyproconazole  (ISO)
D-glucose  (EXP,ISO)
DDE  (EXP,ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deoxypodophyllotoxin  (ISO)
dexamethasone  (EXP,ISO)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
dihydroartemisinin  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
duvoglustat  (EXP)
elemental selenium  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
erythromycin A  (EXP)
erythromycin estolate  (ISO)
esculetin  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
eugenol  (EXP)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
ferulic acid  (EXP)
fipronil  (EXP)
folic acid  (EXP,ISO)
folpet  (EXP)
formaldehyde  (ISO)
fructose  (EXP,ISO)
fulvestrant  (ISO)
furan  (ISO)
gadolinium trichloride  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
Gastrodin  (EXP)
genistein  (EXP,ISO)
geraniol  (ISO)
gingerol  (EXP)
glafenine  (ISO)
glucagon  (EXP)
glucose  (EXP,ISO)
glutathione  (EXP,ISO)
glycine betaine  (ISO)
glyphosate  (EXP)
guggulsterone  (EXP)
GW 3965  (EXP,ISO)
GW 4064  (ISO)
GW 7647  (ISO)
haloperidol  (ISO)
herbacetin  (EXP)
hesperidin  (EXP)
hexadecanoic acid  (EXP,ISO)
hydrazines  (EXP)
ibuprofen  (ISO)
indinavir  (EXP)
isoflavones  (ISO)
isotretinoin  (ISO)
ivermectin  (EXP)
kahweol  (ISO)
L-methionine  (EXP,ISO)
lamivudine  (EXP)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
linoleic acid  (ISO)
linsidomine  (ISO)
lipopolysaccharide  (EXP)
lithocholic acid  (EXP)
losartan  (ISO)
lovastatin  (ISO)
luteolin  (EXP)
LY294002  (ISO)
manganese(II) chloride  (ISO)
melatonin  (EXP)
metformin  (EXP,ISO)
methapyrilene  (ISO)
methimazole  (EXP,ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (EXP)
miconazole  (EXP)
microcystin-LR  (EXP)
mifepristone  (ISO)
Mitotane  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monocrotophos  (ISO)
monosodium L-glutamate  (EXP,ISO)
motexafin gadolinium  (ISO)
myriocin  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
naloxone  (ISO)
naringin  (EXP)
nefazodone  (ISO)
nelfinavir  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (ISO)
nickel sulfate  (EXP,ISO)
nicotine  (EXP,ISO)
nicotinic acid  (ISO)
nimesulide  (ISO)
nitrofen  (ISO)
norethisterone  (ISO)
Norethynodrel  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (EXP,ISO)
olanzapine  (EXP)
olaparib  (EXP)
oleic acid  (EXP,ISO)
oleuropein  (ISO)
Olmesartan medoxomil  (ISO)
orlistat  (EXP,ISO)
oroxylin A  (EXP,ISO)
ozone  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
Paxilline  (ISO)
PD 0325901  (ISO)
penconazole  (EXP)
perfluorobutanesulfonic acid  (EXP)
perfluorobutyric acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP)
phenformin  (ISO)
phenobarbital  (EXP)
phosphatidylcholine  (ISO)
phosphocholine  (ISO)
phosphorylcholine chloride  (ISO)
pimecrolimus  (ISO)
pirinixic acid  (EXP,ISO)
platycodin D  (EXP)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propamocarb  (EXP)
propiconazole  (ISO)
Propiverine  (ISO)
propylparaben  (EXP)
prostaglandin E2  (EXP)
protein kinase inhibitor  (EXP,ISO)
pterostilbene  (ISO)
puerarin  (EXP)
PX-866  (EXP)
pyrroloquinoline quinone  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
raffinose  (EXP,ISO)
resveratrol  (EXP,ISO)
rifampicin  (EXP,ISO)
ritonavir  (ISO)
rotenone  (ISO)
S-allylcysteine  (ISO)
SB 431542  (ISO)
scopoletin  (ISO)
selenium atom  (ISO)
sildenafil citrate  (EXP)
silibinin  (EXP,ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
stavudine  (EXP)
steviol  (EXP)
streptozocin  (EXP,ISO)
sucrose  (EXP)
sulconazole  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP,ISO)
taurine  (EXP)
tebuconazole  (ISO)
teriflunomide  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiazolidinediones  (EXP)
thimerosal  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
trametinib  (ISO)
trans-caffeic acid  (EXP,ISO)
tributylstannane  (EXP,ISO)
trichloroethene  (EXP)
triclocarban  (ISO)
triclosan  (EXP,ISO)
triolein  (EXP)
triphenyl phosphate  (EXP,ISO)
troglitazone  (ISO)
trovafloxacin  (EXP,ISO)
tungsten  (EXP)
tunicamycin  (EXP,ISO)
urethane  (EXP)
ursodeoxycholic acid  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vemurafenib  (ISO)
vorinostat  (ISO)
yohimbine  (EXP)
zidovudine  (EXP,ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2452820   PMID:2920037   PMID:7506544   PMID:7595075   PMID:7803821   PMID:8043949   PMID:8075499   PMID:8661038   PMID:8833906   PMID:9096121   PMID:9271675   PMID:9367675  
PMID:9798653   PMID:9890958   PMID:9922208   PMID:10341080   PMID:10349636   PMID:10409670   PMID:10464095   PMID:10725249   PMID:10922068   PMID:10982846   PMID:11029661   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11254743   PMID:11756683   PMID:12376313   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12588883   PMID:12738878   PMID:12897158   PMID:12904583  
PMID:14522948   PMID:14610273   PMID:14662765   PMID:14668353   PMID:14681479   PMID:15169678   PMID:15306695   PMID:15489334   PMID:15707987   PMID:15782199   PMID:16054078   PMID:16054098  
PMID:16141072   PMID:16141073   PMID:16203972   PMID:16498401   PMID:16894240   PMID:17369526   PMID:17694178   PMID:17786030   PMID:18079124   PMID:18307411   PMID:18591393   PMID:18614015  
PMID:18635971   PMID:18682402   PMID:18706411   PMID:18722179   PMID:18770866   PMID:19029118   PMID:20479009   PMID:20606731   PMID:20657840   PMID:20890301   PMID:21093383   PMID:21098489  
PMID:21180279   PMID:21267068   PMID:21281598   PMID:21387314   PMID:21389266   PMID:21677750   PMID:21757749   PMID:22055502   PMID:22096492   PMID:22331133   PMID:22341463   PMID:22872236  
PMID:22922362   PMID:23000407   PMID:23201681   PMID:23260145   PMID:23269672   PMID:23376793   PMID:23637738   PMID:23675653   PMID:23727646   PMID:24154525   PMID:24223732   PMID:24457600  
PMID:24668799   PMID:24717294   PMID:25249504   PMID:25340345   PMID:25565205   PMID:25574840   PMID:25655684   PMID:25955199   PMID:26220403   PMID:26370502   PMID:26439735   PMID:26508642  
PMID:26670611   PMID:26685326   PMID:26857837   PMID:26910791   PMID:27113764   PMID:27133129   PMID:27307439   PMID:27416896   PMID:27524625   PMID:27545894   PMID:27746183   PMID:27754788  
PMID:27806377   PMID:27858140   PMID:27974211   PMID:28118080   PMID:28281280   PMID:28378742   PMID:28848043   PMID:29385670   PMID:29434029   PMID:29463677   PMID:29475397   PMID:30146486  
PMID:30333137   PMID:30425250   PMID:30562941   PMID:30713523   PMID:30962418   PMID:31063129   PMID:31287803   PMID:31405565   PMID:31545012   PMID:31676791   PMID:31811668   PMID:32035613  
PMID:32325033   PMID:32694609   PMID:32994417  


Genomics

Comparative Map Data
Fasn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,696,784 - 120,715,992 (-)NCBIGRCm39mm39
GRCm3811120,805,958 - 120,825,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,805,846 - 120,824,547 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,667,272 - 120,685,861 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611120,623,167 - 120,640,332 (-)NCBImm8
Celera11132,542,449 - 132,561,038 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.56NCBI
FASN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1782,078,338 - 82,098,294 (-)EnsemblGRCh38hg38GRCh38
GRCh381782,078,338 - 82,098,303 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371780,036,214 - 80,056,106 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,629,503 - 77,649,395 (-)NCBINCBI36hg18NCBI36
Build 341777,629,503 - 77,649,395NCBI
Celera1776,630,560 - 76,648,850 (-)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1775,436,168 - 75,456,057 (-)NCBIHuRef
CHM1_11780,122,440 - 80,142,272 (-)NCBICHM1_1
Fasn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,987,735 - 110,005,901 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,987,735 - 110,005,901 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,579,051 - 109,597,217 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10104,615,873 - 104,634,039 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
Fasn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,063,002 - 1,079,939 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,063,002 - 1,079,939 (+)NCBIChiLan1.0ChiLan1.0
FASN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11782,187,516 - 82,205,647 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1782,187,516 - 82,205,647 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01776,483,108 - 76,503,148 (-)NCBIMhudiblu_PPA_v0panPan3
FASN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl9232,963 - 249,092 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.19233,105 - 249,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fasn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365945,591,785 - 5,609,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FASN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl12920,507 - 937,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.112922,405 - 937,560 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2121,023,512 - 1,032,662 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FASN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,988,410 - 74,008,374 (-)NCBI
ChlSab1.1 Ensembl1673,982,899 - 74,006,551 (-)Ensembl
Fasn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480110,910,022 - 10,926,505 (-)NCBI

Position Markers
Fasn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv3711120,668,414 - 120,668,555UniSTSGRCm37
MGSCv3711120,670,530 - 120,670,786UniSTSGRCm37
Celera11132,545,707 - 132,545,963UniSTS
Celera11132,543,591 - 132,543,732UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
cM Map1172.0UniSTS
UniSTS:236790  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,806,175 - 120,806,436UniSTSGRCm38
MGSCv3711120,667,489 - 120,667,750UniSTSGRCm37
Celera11132,542,666 - 132,542,927UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
PMC156147P10  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,809,451 - 120,809,561UniSTSGRCm38
MGSCv3711120,670,765 - 120,670,875UniSTSGRCm37
Celera11132,545,942 - 132,546,052UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
PMC164451P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,815,605 - 120,815,970UniSTSGRCm38
MGSCv3711120,676,919 - 120,677,284UniSTSGRCm37
Celera11132,552,096 - 132,552,461UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
UniSTS:225262  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,821,996 - 120,822,192UniSTSGRCm38
MGSCv3711120,683,310 - 120,683,506UniSTSGRCm37
Celera11132,558,487 - 132,558,683UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
PMC166350P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,823,952 - 120,824,218UniSTSGRCm38
MGSCv3711120,685,266 - 120,685,532UniSTSGRCm37
Celera11132,560,443 - 132,560,709UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
PMC166350P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,811,304 - 120,811,476UniSTSGRCm38
MGSCv3711120,672,618 - 120,672,790UniSTSGRCm37
Celera11132,547,795 - 132,547,967UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
PMC207565P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,818,048 - 120,818,130UniSTSGRCm38
MGSCv3711120,679,362 - 120,679,444UniSTSGRCm37
Celera11132,554,539 - 132,554,621UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
Fasn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,809,216 - 120,809,472UniSTSGRCm38
MGSCv3711120,670,530 - 120,670,786UniSTSGRCm37
Celera11132,545,707 - 132,545,963UniSTS
Cytogenetic Map11E2UniSTS
Fasn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811120,807,100 - 120,807,241UniSTSGRCm38
MGSCv3711120,668,414 - 120,668,555UniSTSGRCm37
Celera11132,543,591 - 132,543,732UniSTS
Cytogenetic Map11E2UniSTS
cM Map1172.0UniSTS
Fasn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11E2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301095El6_mepilepsy 6 (mouse)Not determined1193338357122082543Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187611774121611872Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196246848122082543Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195513139122082543Mouse
11341721Rvfs2_mRift Valley fever susceptibility 2 (mouse)11100363360120996339Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198461783122082543Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196919310122082543Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191713782122082543Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100167277122082543Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199363361122082543Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195513139122082543Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191713782122082543Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198609643122082543Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101131764122082543Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187600000126900000Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189978425122082543Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1309
Count of miRNA genes:664
Interacting mature miRNAs:798
Transcripts:ENSMUST00000055655, ENSMUST00000146541, ENSMUST00000155276
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF127033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL663090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ125823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000055655   ⟹   ENSMUSP00000052872
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11120,805,846 - 120,824,547 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146541
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11120,808,564 - 120,809,701 (-)Ensembl
RefSeq Acc Id: ENSMUST00000155276
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11120,807,547 - 120,808,605 (-)Ensembl
RefSeq Acc Id: ENSMUST00000205905   ⟹   ENSMUSP00000146068
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11120,822,772 - 120,823,780 (-)Ensembl
RefSeq Acc Id: ENSMUST00000206589   ⟹   ENSMUSP00000145585
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11120,807,105 - 120,824,095 (-)Ensembl
RefSeq Acc Id: ENSMUST00000206637
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl11120,814,495 - 120,815,455 (-)Ensembl
RefSeq Acc Id: NM_007988   ⟹   NP_032014
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911120,696,784 - 120,715,373 (-)NCBI
GRCm3811120,805,958 - 120,824,547 (-)ENTREZGENE
MGSCv3711120,667,272 - 120,685,861 (-)RGD
Celera11132,542,449 - 132,561,038 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030245556   ⟹   XP_030101416
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911120,697,901 - 120,715,992 (-)NCBI
GRCm3811120,807,075 - 120,825,166 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032014   ⟸   NM_007988
- UniProtKB: P19096 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030101416   ⟸   XM_030245556
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000145585   ⟸   ENSMUST00000206589
RefSeq Acc Id: ENSMUSP00000146068   ⟸   ENSMUST00000205905
RefSeq Acc Id: ENSMUSP00000052872   ⟸   ENSMUST00000055655
Protein Domains
Carrier   KR

Promoters
RGD ID:6820864
Promoter ID:MM_KWN:10978
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000009379
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,669,461 - 120,670,652 (-)MPROMDB
RGD ID:6820865
Promoter ID:MM_KWN:10979
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000009378
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,671,026 - 120,671,887 (-)MPROMDB
RGD ID:6848585
Promoter ID:MM_TRO:1872
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   Brain,   Kidney,   Liver,   Lung,   Spleen
Transcripts:MTR012079.11.3281.4
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,673,991 - 120,675,437 (-)MPROMDB
RGD ID:6846832
Promoter ID:MM_ACW:9640
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   Brain,   Liver,   Lung
Transcripts:FASN.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,676,496 - 120,677,487 (-)MPROMDB
RGD ID:6820863
Promoter ID:MM_KWN:10980
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000009377
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611120,685,201 - 120,686,112 (-)MPROMDB
RGD ID:8677748
Promoter ID:EPDNEW_M16904
Type:initiation region
Name:Fasn_1
Description:Mus musculus fatty acid synthase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811120,824,106 - 120,824,166EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95485 AgrOrtholog
Ensembl Genes ENSMUSG00000025153 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000052872 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000145585 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000146068 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000055655 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000205905 UniProtKB/TrEMBL
  ENSMUST00000206589 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.1200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.1470.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.129.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.366.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.47.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ac_transferase_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ACP-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl_transferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Acyl_Trfase/lysoPLipase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fatty_acid_synthase_dom_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KAsynt_C_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ketoacyl_synth_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ketoacyl_synth_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ketoacyl_synth_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Malonyl_transacylase_ACP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Methyltransf_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_Beta-ketoAc_synthase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_dehydratase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_dehydratase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_ER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_KR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_PP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PP-bd_ACP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ppantetheine_attach_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioesterase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thiolase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14104 UniProtKB/Swiss-Prot
MGD MGI:95485 ENTREZGENE
NCBI Gene 14104 ENTREZGENE
Pfam Acyl_transf_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KAsynt_C_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ketoacyl-synt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ketoacyl-synt_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Methyltransf_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF08659 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PP-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS-DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioesterase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fasn PhenoGen
PROSITE B_KETOACYL_SYNTHASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CARRIER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHOPANTETHEINE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PKS_AT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_ER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_KS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKS_PP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47336 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52151 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53335 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53901 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55048 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.236443 ENTREZGENE
UniProt A0A0U1RNJ1_MOUSE UniProtKB/TrEMBL
  A0A0U1RPP5_MOUSE UniProtKB/TrEMBL
  FAS_MOUSE UniProtKB/Swiss-Prot
  O89060_MOUSE UniProtKB/TrEMBL
  P19096 ENTREZGENE
  Q3TB22_MOUSE UniProtKB/TrEMBL
  Q3UHT6_MOUSE UniProtKB/TrEMBL
UniProt Secondary B1ATU8 UniProtKB/Swiss-Prot
  Q6PB72 UniProtKB/Swiss-Prot
  Q8C4Z0 UniProtKB/Swiss-Prot
  Q9EQR0 UniProtKB/Swiss-Prot