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Gene: Mpo (myeloperoxidase) Mus musculus
Symbol: Mpo
Name: myeloperoxidase
Description: Exhibits peroxidase activity. Involved in several processes, including hypochlorous acid biosynthetic process; removal of superoxide radicals; and response to fungus. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and skeleton. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MPO (myeloperoxidase); PARTICIPATES IN etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; interleukin-23 signaling pathway; INTERACTS WITH (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid; (R)-camphor; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA4033; mKIAA4033
Homo sapiens (human) : MPO (myeloperoxidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mpo (myeloperoxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpo (myeloperoxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : MPO (myeloperoxidase)
Canis lupus familiaris (dog) : MPO (myeloperoxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpo (myeloperoxidase)
Sus scrofa (pig) : MPO (myeloperoxidase)
Chlorocebus sabaeus (African green monkey) : MPO (myeloperoxidase)
Heterocephalus glaber (naked mole-rat) : Mpo (myeloperoxidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1187,793,581 - 87,804,413 (+)EnsemblGRCm38mm10GRCm38
GRCm381187,793,784 - 87,804,412 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371187,607,286 - 87,617,914 (+)NCBIGRCm37mm9NCBIm37
MGSCv361187,609,776 - 87,620,592 (+)NCBImm8
Celera1197,389,547 - 97,400,150 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mpo
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10916
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.