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Gene: Mpo (myeloperoxidase) Mus musculus
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Symbol: Mpo
Name: myeloperoxidase
Description: Exhibits peroxidase activity. Involved in several processes, including hypochlorous acid biosynthetic process; removal of superoxide radicals; and response to fungus. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and skeleton. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MPO (myeloperoxidase); PARTICIPATES IN etoposide pharmacodynamics pathway; etoposide pharmacokinetics pathway; interleukin-23 signaling pathway; INTERACTS WITH (4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid; (R)-camphor; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA4033; mKIAA4033
Orthologs:
Homo sapiens (human) : MPO (myeloperoxidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mpo (myeloperoxidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpo (myeloperoxidase)
Pan paniscus (bonobo/pygmy chimpanzee) : MPO (myeloperoxidase)
Canis lupus familiaris (dog) : MPO (myeloperoxidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpo (myeloperoxidase)
Sus scrofa (pig) : MPO (myeloperoxidase)
Chlorocebus sabaeus (African green monkey) : MPO (myeloperoxidase)
Heterocephalus glaber (naked mole-rat) : Mpo (myeloperoxidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1187,793,581 - 87,804,413 (+)EnsemblGRCm38mm10GRCm38
GRCm381187,793,784 - 87,804,412 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371187,607,286 - 87,617,914 (+)NCBIGRCm37mm9NCBIm37
MGSCv361187,609,776 - 87,620,592 (+)NCBImm8
Celera1197,389,547 - 97,400,150 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mpo
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10916
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.