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Gene: Mapkapk3 (mitogen-activated protein kinase-activated protein kinase 3) Mus musculus
Symbol: Mapkapk3
Name: mitogen-activated protein kinase-activated protein kinase 3
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN macropinocytosis; response to lipopolysaccharide; toll-like receptor signaling pathway; PARTICIPATES IN p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH Bacteremia (ortholog); malaria (ortholog); patterned macular dystrophy (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; benzo[a]pyrene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3PK; AI874665; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MapkKapk3; mitogen activated protein kinase-activated protein kinase 3; MK-3; MK3
Homo sapiens (human) : MAPKAPK3 (MAPK activated protein kinase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mapkapk3 (MAPK activated protein kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapkapk3 (MAPK activated protein kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPKAPK3 (MAPK activated protein kinase 3)
Canis lupus familiaris (dog) : MAPKAPK3 (MAPK activated protein kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapkapk3 (MAPK activated protein kinase 3)
Sus scrofa (pig) : MAPKAPK3 (MAPK activated protein kinase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389107,254,927 - 107,289,877 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379107,157,258 - 107,192,208 (-)NCBIGRCm37mm9NCBIm37
MGSCv369107,113,028 - 107,147,978 (-)NCBImm8
Celera9106,860,944 - 106,896,004 (-)NCBICelera
Cytogenetic Map9 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mapkapk3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552084
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.