(+)-alpha-tocopherol multiple interactions ISO RGD:732909 6480464 alpha-Tocopherol inhibits the reaction [28-O-acetylbetulin-3-ylglucopyranoside results in decreased phosphorylation of AKT1 protein] CTD PMID:22343715 (+)-alpha-tocopherol multiple interactions ISO RGD:2081 6480464 alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein] CTD PMID:19351882 (+)-catechin multiple interactions EXP 6480464 [Quercetin co-treated with Catechin] results in increased phosphorylation of AKT1 protein CTD PMID:26363153 (+)-catechin increases phosphorylation ISO RGD:2081 6480464 Catechin results in increased phosphorylation of AKT1 protein CTD PMID:29981789 (+)-catechin decreases phosphorylation ISO RGD:2081 6480464 Catechin results in decreased phosphorylation of AKT1 protein CTD PMID:17302912 (+)-catechin multiple interactions ISO RGD:2081 6480464 [Catechin co-treated with Glucose] results in increased phosphorylation of AKT1 protein, Catechin inhibits the reaction [Peroxynitrous Acid results in increased phosphorylation of AKT1 protein] CTD PMID:17302912 , PMID:29981789 (+)-catechin decreases phosphorylation ISO RGD:732909 6480464 Catechin analog results in decreased phosphorylation of AKT1 protein CTD PMID:16413414 (+)-catechin increases phosphorylation EXP 6480464 Catechin results in increased phosphorylation of AKT1 protein CTD PMID:26363153 (+)-epicatechin-3-O-gallate decreases phosphorylation ISO RGD:732909 6480464 epicatechin gallate results in decreased phosphorylation of AKT1 protein CTD PMID:21945981 (+)-epicatechin-3-O-gallate multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:29061316 (+)-Eudesmin decreases phosphorylation ISO RGD:732909 6480464 eudesmin results in decreased phosphorylation of AKT1 protein CTD PMID:31026422 (+)-pilocarpine decreases phosphorylation ISO RGD:2081 6480464 Pilocarpine results in decreased phosphorylation of AKT1 protein CTD PMID:19429016 (+)-pilocarpine multiple interactions ISO RGD:2081 6480464 [Lithium Chloride co-treated with Pilocarpine] results in increased phosphorylation of AKT1 protein CTD PMID:31018114 (+)-Tetrandrine increases phosphorylation ISO RGD:732909 6480464 tetrandrine results in increased phosphorylation of AKT1 protein CTD PMID:31255635 (+)-Tetrandrine decreases phosphorylation ISO RGD:732909 6480464 tetrandrine results in decreased phosphorylation of AKT1 protein CTD PMID:30549224 (-)-Arctigenin multiple interactions ISO RGD:732909 6480464 [Quercetin co-treated with arctigenin] results in decreased expression of AKT1 protein more ... CTD PMID:25380086 (-)-cotinine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cotinine results in increased phosphorylation of AKT1 protein] CTD PMID:22687995 (-)-cotinine increases phosphorylation ISO RGD:732909 6480464 Cotinine results in increased phosphorylation of AKT1 protein CTD PMID:22687995 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:19244381 more ... (-)-epigallocatechin 3-gallate decreases phosphorylation ISO RGD:732909 6480464 epigallocatechin gallate results in decreased phosphorylation of AKT1 protein CTD PMID:23954321 (-)-gambogic acid decreases activity ISO RGD:732909 6480464 gambogic acid results in decreased activity of AKT1 protein CTD PMID:19433130 (-)-selegiline multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Selegiline co-treated with 1-Methyl-4-phenylpyridinium] results in increased phosphorylation of AKT1 protein], [Selegiline co-treated with 1-Methyl-4-phenylpyridinium] results in increased phosphorylation of AKT1 protein CTD PMID:22019741 (-)-selegiline increases phosphorylation ISO RGD:2081 6480464 Selegiline results in increased phosphorylation of AKT1 protein CTD PMID:22019741 (3,4-dihydroxyphenyl)acetic acid increases phosphorylation ISO RGD:2081 6480464 3, 4-Dihydroxyphenylacetic Acid results in increased phosphorylation of AKT1 protein CTD PMID:29981789 (3,4-dihydroxyphenyl)acetic acid multiple interactions ISO RGD:2081 6480464 [3, 4-Dihydroxyphenylacetic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein CTD PMID:29981789 (R)-carnitine increases phosphorylation ISO RGD:2081 6480464 Carnitine results in increased phosphorylation of AKT1 protein CTD PMID:29186614 (R)-carnitine multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Carnitine results in increased phosphorylation of AKT1 protein] CTD PMID:29186614 (R)-lipoic acid decreases phosphorylation EXP 6480464 Thioctic Acid results in decreased phosphorylation of AKT1 protein CTD PMID:21351249 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in decreased expression of AKT1 mRNA] CTD PMID:27260466 (R)-mevalonic acid multiple interactions ISO RGD:732909 6480464 Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased activity of AKT1 protein], Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased expression of AKT1 mRNA] CTD PMID:17322126 (R)-noradrenaline decreases expression ISO RGD:2081 6480464 Norepinephrine results in decreased expression of AKT1 protein modified form CTD PMID:16338971 (R)-Salsolinol decreases phosphorylation ISO RGD:2081 6480464 salsolinol results in decreased phosphorylation of AKT1 protein CTD PMID:23261589 (S)-naringenin multiple interactions ISO RGD:732909 6480464 naringenin inhibits the reaction [bisphenol A results in increased activity of AKT1 protein], naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] CTD PMID:22692793 , PMID:25866363 (S)-naringenin multiple interactions ISO RGD:2081 6480464 naringenin inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein] CTD PMID:22709785 (S)-nicotine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:12511591 more ... (S)-nicotine increases phosphorylation ISO RGD:732909 6480464 Nicotine results in increased phosphorylation of AKT1 protein CTD PMID:30836163 (S)-nicotine increases phosphorylation ISO RGD:2081 6480464 Nicotine results in increased phosphorylation of AKT1 protein CTD PMID:15983034 (S)-nicotine increases expression ISO RGD:732909 6480464 Nicotine results in increased expression of AKT1 protein modified form CTD PMID:20727180 (Z)-ligustilide decreases phosphorylation ISO RGD:732909 6480464 ligustilide results in decreased phosphorylation of AKT1 protein CTD PMID:23973442 (Z)-ligustilide decreases phosphorylation EXP 6480464 ligustilide results in decreased phosphorylation of AKT1 protein CTD PMID:23973442 1,2-dichloroethane increases phosphorylation EXP 6480464 ethylene dichloride results in increased phosphorylation of AKT1 protein CTD PMID:28189721 1,3-Dinitropyrene multiple interactions EXP 6480464 1, 3-dinitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 1,4-dithiothreitol multiple interactions ISO RGD:732909 6480464 Dithiothreitol inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 1,4-naphthoquinone multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:30871965 1,4-naphthoquinone decreases phosphorylation ISO RGD:732909 6480464 1, 4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein CTD PMID:30871965 1,8-Dinitropyrene multiple interactions EXP 6480464 1, 8-dinitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile multiple interactions ISO RGD:732909 6480464 Citalopram inhibits the reaction [convulxin results in increased phosphorylation of AKT1 protein] CTD PMID:30592962 1-fluoro-2,4-dinitrobenzene increases phosphorylation EXP 6480464 Dinitrofluorobenzene results in increased phosphorylation of AKT1 protein CTD PMID:23445166 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases phosphorylation EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:21856379 , PMID:22891246 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 bis(3)-cognitin inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:22891246 1-nitropyrene multiple interactions EXP 6480464 1-nitropyrene results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17240030 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:732909 6480464 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3 more ... CTD PMID:17550345 , PMID:20103642 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RGD:732909 6480464 lysophosphatidic acid results in increased phosphorylation of AKT1 protein CTD PMID:17550345 , PMID:20103642 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RGD:2081 6480464 lysophosphatidic acid results in increased phosphorylation of AKT1 protein CTD PMID:14769825 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:2081 6480464 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein], exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein] CTD PMID:14769825 14,15-EET increases phosphorylation ISO RGD:732909 6480464 14 more ... CTD PMID:16286479 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 [15-deoxy-delta(12, 14)-prostaglandin J2 co-treated with alitretinoin] results in decreased phosphorylation of AKT1 protein CTD PMID:16611854 16,16-dimethylprostaglandin E2 multiple interactions EXP 6480464 EGFR affects the reaction [16, 16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein] CTD PMID:15578100 16,16-dimethylprostaglandin E2 increases phosphorylation EXP 6480464 16, 16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein CTD PMID:15578100 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of AKT1 mRNA CTD PMID:17555576 , PMID:17942748 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AKT1 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO RGD:732909 6480464 1-(4-(6-bromobenzo(1 more ... CTD PMID:16168102 more ... 17beta-estradiol increases phosphorylation ISO RGD:2081 6480464 Estradiol results in increased phosphorylation of AKT1 protein CTD PMID:15590986 , PMID:16951259 17beta-estradiol multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein] more ... CTD PMID:15845746 , PMID:25461906 17beta-estradiol increases phosphorylation EXP 6480464 Estradiol results in increased phosphorylation of AKT1 protein CTD PMID:15845746 more ... 17beta-estradiol increases phosphorylation ISO RGD:732909 6480464 Estradiol results in increased phosphorylation of AKT1 protein CTD PMID:16168102 more ... 17beta-estradiol decreases expression ISO RGD:732909 6480464 Estradiol results in decreased expression of AKT1 mRNA CTD PMID:23373633 17beta-estradiol multiple interactions ISO RGD:2081 6480464 [Estradiol co-treated with fulvestrant] results in increased phosphorylation of AKT1 protein more ... CTD PMID:11375906 more ... 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of AKT1 mRNA CTD PMID:15598610 17beta-estradiol 17-glucosiduronic acid multiple interactions ISO RGD:2081 6480464 tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of AKT1 protein] CTD PMID:29090346 17beta-estradiol 17-glucosiduronic acid increases phosphorylation ISO RGD:2081 6480464 estradiol-17 beta-glucuronide results in increased phosphorylation of AKT1 protein CTD PMID:29090346 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:732909 6480464 bicalutamide inhibits the reaction [Metribolone results in increased phosphorylation of AKT1 protein], Hydrogen Peroxide promotes the reaction [Metribolone results in increased phosphorylation of AKT1 protein] CTD PMID:17325745 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases phosphorylation ISO RGD:732909 6480464 Metribolone results in increased phosphorylation of AKT1 protein CTD PMID:17325745 17beta-hydroxy-5alpha-androstan-3-one decreases activity EXP 6480464 Dihydrotestosterone analog results in decreased activity of AKT1 CTD PMID:17303658 2,2',4,4',5,5'-hexachlorobiphenyl increases phosphorylation ISO RGD:2081 6480464 2 more ... CTD PMID:24726520 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:732909 6480464 2 more ... CTD PMID:25644787 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO RGD:732909 6480464 2 more ... CTD PMID:25644787 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:11309286 more ... 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of AKT1 protein CTD PMID:28302560 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:732909 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of AKT1 protein CTD PMID:27312872 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:2081 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of AKT1 protein CTD PMID:24231000 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:2081 6480464 AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:23639626 , PMID:24231000 2,3,7,8-tetrachlorodibenzodioxine decreases phosphorylation ISO RGD:2081 6480464 Tetrachlorodibenzodioxin results in decreased phosphorylation of AKT1 protein CTD PMID:23639626 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of AKT1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of AKT1 protein], [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of AKT1 mRNA CTD PMID:17942748 , PMID:28302560 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO RGD:732909 6480464 Tetrachlorodibenzodioxin results in increased activity of AKT1 protein CTD PMID:16051281 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions ISO RGD:2081 6480464 2 more ... CTD PMID:24218147 2,4-dinitrotoluene affects expression ISO RGD:2081 6480464 2, 4-dinitrotoluene affects the expression of AKT1 mRNA CTD PMID:21346803 2,6-di-tert-butyl-4-methylphenol increases phosphorylation ISO RGD:2081 6480464 Butylated Hydroxytoluene results in increased phosphorylation of AKT1 protein CTD PMID:17604070 2-acetamidofluorene multiple interactions ISO RGD:732909 6480464 2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein, [2-Acetylaminofluorene results in increased activity of AKT1 protein] which results in increased expression of ABCB1 mRNA CTD PMID:11960367 2-acetamidofluorene multiple interactions EXP 6480464 2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein, Phycocyanin inhibits the reaction [2-Acetylaminofluorene results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17303067 2-amino-2-deoxy-D-glucopyranose affects phosphorylation ISO RGD:732909 6480464 Glucosamine analog affects the phosphorylation of AKT1 protein CTD PMID:18080321 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein], OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:732909 6480464 Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein], Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] CTD PMID:18080321 , PMID:18340449 2-chloroethanol increases phosphorylation EXP 6480464 Ethylene Chlorohydrin results in increased phosphorylation of AKT1 protein CTD PMID:26962056 2-methoxy-17beta-estradiol multiple interactions ISO RGD:732909 6480464 2-Methoxyestradiol inhibits the reaction [Quercetin results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:26011145 2-methoxy-17beta-estradiol decreases phosphorylation ISO RGD:732909 6480464 2-Methoxyestradiol results in decreased phosphorylation of AKT1 protein CTD PMID:26011145 2-methylcholine affects expression ISO RGD:732909 6480464 beta-methylcholine affects the expression of AKT1 mRNA CTD PMID:21179406 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of AKT1 protein] CTD PMID:23112101 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO RGD:732909 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of AKT1 mRNA] CTD PMID:18031796 20-hydroxyecdysone multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased activity of AKT1 protein]], Ecdysterone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased activity of AKT1 protein] CTD PMID:26048653 3',5'-cyclic GMP multiple interactions ISO RGD:2081 6480464 AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Cyclic GMP] CTD PMID:12891555 3,3',4,4',5-pentachlorobiphenyl affects expression ISO RGD:732909 6480464 3 more ... CTD PMID:21703328 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:732909 6480464 3 more ... CTD PMID:24709675 3,3',5,5'-tetrabromobisphenol A increases activity EXP 6480464 tetrabromobisphenol A results in increased activity of AKT1 protein CTD PMID:20077215 3,3',5,5'-tetrabromobisphenol A increases acetylation ISO RGD:2081 6480464 tetrabromobisphenol A results in increased acetylation of AKT1 protein CTD PMID:31332466 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Triiodothyronine results in increased phosphorylation of AKT1 protein], AKT1 protein affects the reaction [Triiodothyronine affects the expression of TTN mRNA] CTD PMID:18096819 3,3',5-triiodo-L-thyronine increases phosphorylation ISO RGD:2081 6480464 Triiodothyronine results in increased phosphorylation of AKT1 protein CTD PMID:16021636 , PMID:18096819 3,3',5-triiodo-L-thyronine increases phosphorylation ISO RGD:732909 6480464 Triiodothyronine results in increased phosphorylation of AKT1 protein CTD PMID:16021636 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of AKT1 mRNA CTD PMID:20188158 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:732909 6480464 bisindolylmaleimide I inhibits the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein], bisindolylmaleimide I results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:16236484 3-hydroxyisovaleric acid multiple interactions ISO RGD:2081 6480464 [Dexamethasone co-treated with beta-hydroxyisovaleric acid] results in increased phosphorylation of AKT1 protein CTD PMID:24124592 3-iodobenzyl-5'-N-methylcarboxamidoadenosine multiple interactions ISO RGD:732909 6480464 Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein], wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein] CTD PMID:16116186 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of AKT1 protein more ... CTD PMID:25559859 , PMID:30665118 3-methyladenine decreases phosphorylation ISO RGD:732909 6480464 3-methyladenine results in decreased phosphorylation of AKT1 protein CTD PMID:16882451 3-methylcholanthrene increases expression ISO RGD:2081 6480464 Methylcholanthrene results in increased expression of AKT1 mRNA CTD PMID:29094188 3-methylcholanthrene multiple interactions ISO RGD:2081 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter], alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA] CTD PMID:29094188 3-methylcholanthrene decreases acetylation ISO RGD:2081 6480464 Methylcholanthrene results in decreased acetylation of AKT1 promoter CTD PMID:29094188 3-Nitrofluoranthene increases phosphorylation EXP 6480464 3-nitrofluoranthene results in increased phosphorylation of AKT1 protein CTD PMID:19041363 3-nitropropanoic acid multiple interactions ISO RGD:2081 6480464 topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of AKT1 protein] CTD PMID:29753867 3-nitropropanoic acid decreases phosphorylation ISO RGD:2081 6480464 3-nitropropionic acid results in decreased phosphorylation of AKT1 protein CTD PMID:29753867 3-phenylprop-2-enal increases phosphorylation ISO RGD:732909 6480464 cinnamic aldehyde results in increased phosphorylation of AKT1 protein CTD PMID:21469739 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamic aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] CTD PMID:20467561 4'-epidoxorubicin multiple interactions EXP 6480464 paeonol inhibits the reaction [Epirubicin results in decreased phosphorylation of AKT1 protein] CTD PMID:26646421 4'-epidoxorubicin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Epirubicin results in increased phosphorylation of AKT1 protein], paeonol inhibits the reaction [Epirubicin results in increased phosphorylation of AKT1 protein] CTD PMID:29505745 4'-epidoxorubicin increases phosphorylation ISO RGD:2081 6480464 Epirubicin results in increased phosphorylation of AKT1 protein CTD PMID:29505745 4'-epidoxorubicin decreases phosphorylation EXP 6480464 Epirubicin results in decreased phosphorylation of AKT1 protein CTD PMID:26646421 4,4'-sulfonyldiphenol decreases expression ISO RGD:2081 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of AKT1 mRNA CTD PMID:26186136 4,4'-sulfonyldiphenol increases acetylation ISO RGD:2081 6480464 bis(4-hydroxyphenyl)sulfone results in increased acetylation of AKT1 protein CTD PMID:31332466 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:12511591 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:12511591 4-aminophenol decreases phosphorylation ISO RGD:732909 6480464 4-aminophenol results in decreased phosphorylation of AKT1 protein CTD PMID:22162043 4-hydroxy-17beta-estradiol multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-hydroxyestradiol results in increased phosphorylation of AKT1 protein], wortmannin inhibits the reaction [4-hydroxyestradiol results in increased phosphorylation of AKT1 protein] CTD PMID:15050414 4-hydroxy-17beta-estradiol increases phosphorylation ISO RGD:732909 6480464 4-hydroxyestradiol results in increased phosphorylation of AKT1 protein CTD PMID:15050414 4-hydroxynon-2-enal affects response to substance ISO RGD:2081 6480464 AKT1 protein affects the susceptibility to 4-hydroxy-2-nonenal CTD PMID:18805481 4-hydroxynon-2-enal decreases phosphorylation ISO RGD:732909 6480464 4-hydroxy-2-nonenal results in decreased phosphorylation of AKT1 protein CTD PMID:24825450 4-hydroxynon-2-enal increases activity ISO RGD:732909 6480464 4-hydroxy-2-nonenal results in increased activity of AKT1 protein CTD PMID:23845594 4-hydroxynon-2-enal multiple interactions ISO RGD:2081 6480464 AKT1 protein affects the reaction [4-hydroxy-2-nonenal results in increased expression of MMP2 protein] CTD PMID:18805481 4-hydroxyphenyl retinamide multiple interactions ISO RGD:732909 6480464 Fenretinide inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein], Fenretinide inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:16230421 , PMID:25246272 4-nonylphenol multiple interactions ISO RGD:2081 6480464 [bisphenol A co-treated with 4-nonylphenol] results in increased expression of AKT1 mRNA more ... CTD PMID:26804764 , PMID:30228064 4-nonylphenol decreases expression ISO RGD:2081 6480464 4-nonylphenol results in decreased expression of AKT1 mRNA CTD PMID:30228064 4-nonylphenol decreases phosphorylation ISO RGD:2081 6480464 4-nonylphenol results in decreased phosphorylation of AKT1 protein CTD PMID:26804764 4-phenylbutyric acid multiple interactions ISO RGD:2081 6480464 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] CTD PMID:25398788 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in decreased phosphorylation of AKT1 protein] CTD PMID:31298478 4-phenylbutyric acid multiple interactions ISO RGD:732909 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein] CTD PMID:28245985 4-vinylcyclohexene dioxide increases expression EXP 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of AKT1 mRNA CTD PMID:20829426 5-(1,4-diazepane-1-sulfonyl)isoquinoline multiple interactions ISO RGD:2081 6480464 fasudil results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17761835 5-(2-chloroethyl)-4-methylthiazole multiple interactions EXP 6480464 Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of AKT1 protein] CTD PMID:24892905 5-aza-2'-deoxycytidine increases phosphorylation ISO RGD:732909 6480464 Decitabine results in increased phosphorylation of AKT1 protein CTD PMID:21170675 5-aza-2'-deoxycytidine decreases activity ISO RGD:732909 6480464 Decitabine results in decreased activity of AKT1 protein CTD PMID:17283156 , PMID:18636160 5-aza-2'-deoxycytidine multiple interactions ISO RGD:732909 6480464 AKT1 protein inhibits the reaction [Decitabine results in increased expression of TNFSF10 protein], Decitabine inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:17283156 , PMID:30191986 5-azacytidine multiple interactions ISO RGD:732909 6480464 Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22841775 5-chloro-7-iodoquinolin-8-ol multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of AKT1 protein], [Clioquinol co-treated with Copper] results in increased phosphorylation of AKT1 protein CTD PMID:16648635 5-fluorouracil multiple interactions ISO RGD:732909 6480464 [Apigenin co-treated with Fluorouracil] results in decreased expression of AKT1 protein more ... CTD PMID:17918158 more ... 5-fluorouracil affects phosphorylation ISO RGD:732909 6480464 Fluorouracil affects the phosphorylation of AKT1 protein CTD PMID:24095863 5-fluorouracil multiple interactions EXP 6480464 Fluorouracil inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] CTD PMID:16724238 5-fluorouracil increases phosphorylation ISO RGD:732909 6480464 Fluorouracil results in increased phosphorylation of AKT1 protein CTD PMID:18794807 5-methoxypsoralen decreases phosphorylation ISO RGD:732909 6480464 5-Methoxypsoralen results in decreased phosphorylation of AKT1 protein CTD PMID:30576070 5-methoxypsoralen multiple interactions ISO RGD:732909 6480464 pifithrin inhibits the reaction [5-Methoxypsoralen results in decreased phosphorylation of AKT1 protein] CTD PMID:30576070 6,7-dimethoxy-2-phenylquinoxaline multiple interactions ISO RGD:732909 6480464 6, 7-dimethoxy-2-phenylquinoxaline inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:25896968 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:732909 6480464 6-chloro-2 more ... CTD PMID:25536389 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:26450947 6-propyl-2-thiouracil multiple interactions EXP 6480464 AKT1 protein mutant form promotes the reaction [Propylthiouracil results in increased expression of AMH mRNA], AKT1 protein mutant form promotes the reaction [Propylthiouracil results in increased expression of INHBB mRNA] CTD PMID:20951798 6-propyl-2-thiouracil affects response to substance EXP 6480464 AKT1 protein affects the susceptibility to Propylthiouracil CTD PMID:20951798 6alpha-methylprednisolone decreases phosphorylation ISO RGD:2081 6480464 Methylprednisolone results in decreased phosphorylation of AKT1 protein CTD PMID:15187100 , PMID:30878453 6alpha-methylprednisolone multiple interactions ISO RGD:2081 6480464 naringin inhibits the reaction [Methylprednisolone results in decreased phosphorylation of AKT1 protein] CTD PMID:30878453 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:21785161 7,12-dimethyltetraphene increases expression ISO RGD:2081 6480464 9 more ... CTD PMID:24576726 7,12-dimethyltetraphene increases phosphorylation ISO RGD:2081 6480464 9 more ... CTD PMID:24576726 7-ketocholesterol multiple interactions ISO RGD:2081 6480464 7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein, alpha-Tocopherol inhibits the reaction [7-ketocholesterol results in decreased phosphorylation of and results in decreased activity of AKT1 protein] CTD PMID:19351882 8-(4-chlorophenylthio)-cAMP increases phosphorylation ISO RGD:2081 6480464 8-((4-chlorophenyl)thio)cyclic-3', 5'-AMP results in increased phosphorylation of AKT1 protein CTD PMID:20610540 8-Br-cAMP decreases expression ISO RGD:732909 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AKT1 mRNA CTD PMID:22079614 9,10-anthraquinone multiple interactions ISO RGD:732909 6480464 9, 10-anthraquinone analog results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:26915975 9-cis-retinoic acid increases phosphorylation ISO RGD:2081 6480464 Alitretinoin results in increased phosphorylation of AKT1 protein CTD PMID:18063688 9-cis-retinoic acid multiple interactions EXP 6480464 [15-deoxy-delta(12, 14)-prostaglandin J2 co-treated with Alitretinoin] results in decreased phosphorylation of AKT1 protein CTD PMID:16611854 9-cis-retinoic acid increases phosphorylation EXP 6480464 Alitretinoin results in increased phosphorylation of AKT1 protein CTD PMID:16288212 9-cis-retinoic acid decreases phosphorylation EXP 6480464 Alitretinoin results in decreased phosphorylation of AKT1 protein CTD PMID:16288212 9-cis-retinoic acid decreases phosphorylation ISO RGD:732909 6480464 Alitretinoin results in decreased phosphorylation of AKT1 protein CTD PMID:16340750 [6]-Shogaol multiple interactions EXP 6480464 shogaol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] CTD PMID:18683823 abamectin decreases expression ISO RGD:732909 6480464 abamectin results in decreased expression of AKT1 protein CTD PMID:30958899 acetylsalicylic acid multiple interactions ISO RGD:732909 6480464 [troglitazone co-treated with Aspirin] results in decreased expression of AKT1 protein more ... CTD PMID:19908241 , PMID:20116423 acetylsalicylic acid increases expression ISO RGD:732909 6480464 Aspirin results in increased expression of AKT1 mRNA CTD PMID:20457246 acetylsalicylic acid increases activity ISO RGD:732909 6480464 Aspirin results in increased activity of AKT1 protein CTD PMID:21617849 acrolein multiple interactions ISO RGD:732909 6480464 Acrolein results in increased expression of and results in increased phosphorylation of AKT1 protein CTD PMID:19596284 acrolein multiple interactions EXP 6480464 Acrolein inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein] CTD PMID:24812010 acrolein multiple interactions ISO RGD:2081 6480464 [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of AKT1 protein CTD PMID:24847785 actinomycin D multiple interactions EXP 6480464 PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:14640974 actinomycin D multiple interactions ISO RGD:732909 6480464 PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:14640974 afimoxifene increases phosphorylation ISO RGD:732909 6480464 afimoxifene results in increased phosphorylation of AKT1 protein CTD PMID:19549922 afimoxifene decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to afimoxifene CTD PMID:18351453 aflatoxin B1 multiple interactions ISO RGD:732909 6480464 [CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of AKT1 protein, MIR138-1 mRNA alternative form inhibits the reaction [[CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of AKT1 protein] CTD PMID:26084420 aflatoxin B1 decreases methylation ISO RGD:732909 6480464 Aflatoxin B1 results in decreased methylation of AKT1 intron CTD PMID:30157460 aflatoxin M1 decreases phosphorylation ISO RGD:732909 6480464 Aflatoxin M1 results in decreased phosphorylation of AKT1 protein CTD PMID:30928695 AH23848 multiple interactions ISO RGD:732909 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to AKT1 protein], [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of AKT1 protein CTD PMID:19407222 AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in decreased oxidation of Fatty Acids] more ... CTD PMID:15806154 AICA ribonucleotide increases phosphorylation EXP 6480464 AICA ribonucleotide results in increased phosphorylation of AKT1 protein CTD PMID:22137261 AICA ribonucleotide decreases phosphorylation EXP 6480464 AICA ribonucleotide results in decreased phosphorylation of AKT1 protein CTD PMID:25603053 alachlor multiple interactions EXP 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein, [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 alcohol multiple interactions ISO RGD:732909 6480464 Alcohols inhibits the reaction [Adenosine Triphosphate results in decreased activity of AKT1 protein] CTD PMID:24300283 aldehydo-D-glucosamine affects phosphorylation ISO RGD:732909 6480464 Glucosamine analog affects the phosphorylation of AKT1 protein CTD PMID:18080321 aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein], OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] CTD PMID:30602124 aldehydo-D-glucosamine multiple interactions ISO RGD:732909 6480464 Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein], Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] CTD PMID:18080321 , PMID:18340449 aldehydo-D-glucose multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:18004065 more ... aldehydo-D-glucose increases phosphorylation ISO RGD:2081 6480464 Glucose results in increased phosphorylation of AKT1 protein CTD PMID:23159718 more ... aldehydo-D-glucose decreases phosphorylation ISO RGD:732909 6480464 Glucose results in decreased phosphorylation of AKT1 protein CTD PMID:21333731 more ... aldehydo-D-glucose decreases phosphorylation ISO RGD:2081 6480464 Glucose results in decreased phosphorylation of AKT1 protein CTD PMID:23453443 more ... aldehydo-D-glucose multiple interactions EXP 6480464 [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein more ... CTD PMID:15806154 more ... aldehydo-D-glucose multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:16385087 more ... aldehydo-D-glucose decreases expression ISO RGD:2081 6480464 Glucose results in decreased expression of AKT1 protein modified form CTD PMID:18004065 aldehydo-D-glucose increases response to substance EXP 6480464 AKT1 protein mutant form results in increased susceptibility to Glucose deficiency CTD PMID:15806154 aldehydo-D-glucose increases phosphorylation ISO RGD:732909 6480464 Glucose results in increased phosphorylation of AKT1 protein CTD PMID:21333731 all-trans-retinoic acid multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tretinoin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:16417524 more ... all-trans-retinoic acid decreases expression ISO RGD:732909 6480464 Tretinoin results in decreased expression of AKT1 protein CTD PMID:30093655 all-trans-retinoic acid increases phosphorylation ISO RGD:732909 6480464 Tretinoin results in increased phosphorylation of AKT1 protein CTD PMID:16043647 more ... all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of AKT1 mRNA CTD PMID:22498432 all-trans-retinoic acid multiple interactions ISO RGD:2081 6480464 [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with Tretinoin] results in decreased phosphorylation of AKT1 protein more ... CTD PMID:25203460 all-trans-retinoic acid decreases phosphorylation EXP 6480464 Tretinoin results in decreased phosphorylation of AKT1 protein CTD PMID:16288212 all-trans-retinoic acid increases phosphorylation EXP 6480464 Tretinoin results in increased phosphorylation of AKT1 protein CTD PMID:16288212 all-trans-retinoic acid multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tretinoin results in increased activity of AKT1 protein] more ... CTD PMID:16288212 , PMID:16613989 all-trans-retinoic acid decreases phosphorylation ISO RGD:732909 6480464 Tretinoin results in decreased phosphorylation of AKT1 protein CTD PMID:17259349 all-trans-retinoic acid decreases activity ISO RGD:732909 6480464 Tretinoin results in decreased activity of AKT1 protein CTD PMID:16456186 all-trans-retinoic acid decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Tretinoin CTD PMID:12556562 all-trans-retinol multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vitamin A results in increased phosphorylation of AKT1 protein] more ... CTD PMID:21807062 all-trans-retinol increases phosphorylation ISO RGD:2081 6480464 Vitamin A results in increased phosphorylation of AKT1 protein CTD PMID:21807062 alloxan decreases phosphorylation EXP 6480464 Alloxan results in decreased phosphorylation of AKT1 protein CTD PMID:26827782 alloxan multiple interactions EXP 6480464 Phycocyanin inhibits the reaction [Alloxan results in decreased phosphorylation of AKT1 protein] CTD PMID:26827782 alpha-mangostin decreases phosphorylation ISO RGD:732909 6480464 mangostin results in decreased phosphorylation of AKT1 protein CTD PMID:23954321 alpha-naphthoflavone increases methylation ISO RGD:2081 6480464 alpha-naphthoflavone results in increased methylation of AKT1 promoter CTD PMID:29094188 alpha-naphthoflavone multiple interactions ISO RGD:2081 6480464 alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter], alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA] CTD PMID:29094188 alvocidib multiple interactions ISO RGD:732909 6480464 [alvocidib co-treated with Bortezomib] results in decreased expression of AKT1 protein modified form CTD PMID:15039284 AM-251 multiple interactions ISO RGD:732909 6480464 AM 251 inhibits the reaction [Dronabinol results in decreased phosphorylation of and results in decreased activity of AKT1 protein] CTD PMID:17583570 amidotrizoic acid decreases phosphorylation ISO RGD:732909 6480464 Diatrizoate results in decreased phosphorylation of AKT1 protein CTD PMID:25603236 amidotrizoic acid multiple interactions ISO RGD:732909 6480464 Plant Extracts inhibits the reaction [Diatrizoate results in decreased phosphorylation of AKT1 protein] CTD PMID:25603236 amiloride multiple interactions ISO RGD:732909 6480464 Amiloride results in decreased phosphorylation of and results in decreased activity of AKT1 protein, Okadaic Acid inhibits the reaction [Amiloride results in decreased phosphorylation of AKT1 protein] CTD PMID:15607733 , PMID:16059913 amiodarone decreases phosphorylation ISO RGD:732909 6480464 Amiodarone results in decreased phosphorylation of AKT1 protein CTD PMID:23912912 ammonium chloride decreases expression ISO RGD:2081 6480464 Ammonium Chloride results in decreased expression of AKT1 protein, Ammonium Chloride results in decreased expression of AKT1 protein modified form CTD PMID:16483693 ammonium chloride increases phosphorylation ISO RGD:2081 6480464 Ammonium Chloride results in increased phosphorylation of AKT1 protein CTD PMID:16678351 amosite asbestos increases activity EXP 6480464 Asbestos, Amosite results in increased activity of AKT1 protein CTD PMID:29112861 amphetamine affects response to substance EXP 6480464 AKT1 protein affects the susceptibility to Amphetamine CTD PMID:14745448 anethole decreases phosphorylation ISO RGD:732909 6480464 anethole results in decreased phosphorylation of AKT1 protein CTD PMID:21212515 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:732909 6480464 pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein] more ... CTD PMID:17341418 more ... anthra[1,9-cd]pyrazol-6(2H)-one decreases expression ISO RGD:2081 6480464 pyrazolanthrone results in decreased expression of AKT1 protein CTD PMID:16046226 antigen increases phosphorylation EXP 6480464 Antigens results in increased phosphorylation of AKT1 protein CTD PMID:21958720 antigen multiple interactions EXP 6480464 Quinoxalines analog inhibits the reaction [Antigens results in increased phosphorylation of AKT1 protein] CTD PMID:21958720 ANTIMYCIN increases phosphorylation EXP 6480464 antimycin results in increased phosphorylation of AKT1 protein CTD PMID:19901985 antimycin A multiple interactions EXP 6480464 Luteolin inhibits the reaction [Antimycin A results in decreased activity of AKT1 protein] CTD PMID:21782929 antimycin A decreases activity EXP 6480464 Antimycin A results in decreased activity of AKT1 protein CTD PMID:21466842 , PMID:21782929 apigenin multiple interactions ISO RGD:732909 6480464 [Apigenin co-treated with Fluorouracil] results in decreased expression of AKT1 protein CTD PMID:19885610 apigenin decreases expression ISO RGD:732909 6480464 Apigenin results in decreased expression of AKT1 protein CTD PMID:15947208 apocynin multiple interactions ISO RGD:732909 6480464 acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] CTD PMID:26514923 arachidonic acid increases phosphorylation EXP 6480464 Arachidonic Acid results in increased phosphorylation of AKT1 protein CTD PMID:19344371 arachidonic acid multiple interactions EXP 6480464 aristolochic acid I inhibits the reaction [Arachidonic Acid results in increased phosphorylation of AKT1 protein] CTD PMID:19344371 arecoline multiple interactions ISO RGD:732909 6480464 [arecoline hydrobromide results in increased abundance of Arecoline] inhibits the reaction [2-amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:30910432 aristolochic acid multiple interactions EXP 6480464 aristolochic acid I inhibits the reaction [Arachidonic Acid results in increased phosphorylation of AKT1 protein] CTD PMID:19344371 arotinoid acid decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to 4-(2-(5 more ... CTD PMID:16417524 arsane increases phosphorylation ISO RGD:732909 6480464 Arsenic analog results in increased phosphorylation of AKT1 protein CTD PMID:24582688 arsane multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of and affects the localization of AKT1 protein] CTD PMID:24582688 arsenic acid decreases phosphorylation EXP 6480464 arsenic acid results in decreased phosphorylation of AKT1 protein CTD PMID:26763397 arsenic atom multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of and affects the localization of AKT1 protein] CTD PMID:24582688 arsenic atom increases phosphorylation ISO RGD:732909 6480464 Arsenic analog results in increased phosphorylation of AKT1 protein CTD PMID:24582688 arsenic trichloride multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein] more ... CTD PMID:22696236 , PMID:25944616 arsenic trichloride increases phosphorylation ISO RGD:732909 6480464 arsenic trichloride results in increased phosphorylation of AKT1 protein CTD PMID:25944616 arsenic trichloride multiple interactions EXP 6480464 MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein], MAPK9 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein] CTD PMID:22696236 arsenic trichloride increases activity ISO RGD:732909 6480464 arsenic trichloride results in increased activity of AKT1 protein CTD PMID:22696236 arsenite(3-) increases phosphorylation ISO RGD:732909 6480464 arsenite results in increased phosphorylation of AKT1 protein CTD PMID:12640124 more ... arsenite(3-) increases methylation ISO RGD:732909 6480464 arsenite results in increased methylation of AKT1 promoter CTD PMID:23974009 arsenite(3-) decreases phosphorylation EXP 6480464 arsenite results in decreased phosphorylation of AKT1 protein CTD PMID:17520061 arsenite(3-) increases phosphorylation ISO RGD:2081 6480464 arsenite results in increased phosphorylation of AKT1 protein CTD PMID:20377179 arsenite(3-) multiple interactions ISO RGD:2081 6480464 arsenite results in decreased expression of and results in decreased phosphorylation of AKT1 protein more ... CTD PMID:20377179 , PMID:29324385 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of AKT1 protein CTD PMID:15276423 arsenite(3-) increases activity ISO RGD:732909 6480464 arsenite results in increased activity of AKT1 protein CTD PMID:22040890 arsenite(3-) multiple interactions EXP 6480464 AKT1 protein modified form inhibits the reaction [arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]] more ... CTD PMID:17520061 , PMID:20835880 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of AKT1 mRNA CTD PMID:18191166 arsenite(3-) increases phosphorylation EXP 6480464 arsenite results in increased phosphorylation of AKT1 protein CTD PMID:20835880 arsenite(3-) decreases expression ISO RGD:732909 6480464 arsenite results in decreased expression of AKT1 mRNA CTD PMID:18585952 arsenite(3-) multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in increased activity of AKT1 protein] more ... CTD PMID:11788791 more ... arsenous acid affects stability ISO RGD:732909 6480464 Arsenic Trioxide affects the stability of AKT1 protein CTD PMID:18566239 arsenous acid decreases expression ISO RGD:732909 6480464 Arsenic Trioxide results in decreased expression of AKT1 mRNA, Arsenic Trioxide results in decreased expression of AKT1 protein CTD PMID:20458559 , PMID:30093655 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of AKT1 mRNA CTD PMID:30032600 , PMID:30225639 arsenous acid increases phosphorylation ISO RGD:732909 6480464 Arsenic Trioxide results in increased phosphorylation of AKT1 protein CTD PMID:25791921 , PMID:29266867 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of AKT1 protein CTD PMID:15688020 , PMID:21078540 arsenous acid multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:12168106 more ... arsenous acid multiple interactions EXP 6480464 Arsenic Trioxide inhibits the reaction [AKT1 protein binds to PPARG protein] more ... CTD PMID:15916724 more ... arsenous acid increases activity ISO RGD:732909 6480464 Arsenic Trioxide results in increased activity of AKT1 protein CTD PMID:19457607 arsenous acid decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Arsenic Trioxide, AKT1 results in decreased susceptibility to Arsenic Trioxide CTD PMID:16115127 more ... arsenous acid decreases phosphorylation ISO RGD:732909 6480464 Arsenic Trioxide results in decreased phosphorylation of AKT1 protein CTD PMID:16434995 more ... arsenous acid decreases phosphorylation EXP 6480464 Arsenic Trioxide results in decreased phosphorylation of AKT1 protein CTD PMID:20299303 , PMID:30362509 astilbin multiple interactions ISO RGD:732909 6480464 astilbin inhibits the reaction [Cisplatin results in decreased phosphorylation of AKT1 protein] CTD PMID:29471006 atorvastatin calcium multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of AKT1 protein] CTD PMID:20305681 atorvastatin calcium increases phosphorylation EXP 6480464 Atorvastatin results in increased phosphorylation of AKT1 protein CTD PMID:19526287 atorvastatin calcium multiple interactions ISO RGD:2081 6480464 coenzyme Q10 inhibits the reaction [Atorvastatin results in decreased phosphorylation of AKT1 protein] CTD PMID:27345130 atorvastatin calcium decreases phosphorylation ISO RGD:2081 6480464 Atorvastatin results in decreased phosphorylation of AKT1 protein CTD PMID:27345130 , PMID:27815113 atorvastatin calcium multiple interactions ISO RGD:732909 6480464 [Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of AKT1 protein, Atorvastatin results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:18172863 , PMID:29630879 ATP decreases activity ISO RGD:732909 6480464 Adenosine Triphosphate results in decreased activity of AKT1 protein CTD PMID:24300283 ATP multiple interactions ISO RGD:732909 6480464 Alcohols inhibits the reaction [Adenosine Triphosphate results in decreased activity of AKT1 protein] CTD PMID:24300283 atrazine increases phosphorylation ISO RGD:732909 6480464 Atrazine results in increased phosphorylation of AKT1 protein CTD PMID:18461179 atrazine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Atrazine results in decreased expression of and results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:27431321 atrazine increases expression ISO RGD:732909 6480464 Atrazine results in increased expression of AKT1 mRNA CTD PMID:22378314 atrazine decreases phosphorylation ISO RGD:732909 6480464 Atrazine results in decreased phosphorylation of AKT1 protein CTD PMID:22378314 aucubin increases phosphorylation ISO RGD:732909 6480464 aucubin results in increased phosphorylation of AKT1 protein CTD PMID:29408431 azathioprine multiple interactions ISO RGD:732909 6480464 Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:23958494 baicalein decreases phosphorylation ISO RGD:732909 6480464 baicalein results in decreased phosphorylation of AKT1 protein CTD PMID:22820424 baicalein increases phosphorylation ISO RGD:732909 6480464 baicalein results in increased phosphorylation of AKT1 protein CTD PMID:18025287 baicalein multiple interactions ISO RGD:732909 6480464 Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein], wortmannin inhibits the reaction [baicalein results in increased phosphorylation of AKT1 protein] CTD PMID:18025287 , PMID:22820424 BAPTA multiple interactions ISO RGD:2081 6480464 1 more ... CTD PMID:25433145 belinostat increases phosphorylation ISO RGD:732909 6480464 belinostat results in increased phosphorylation of AKT1 protein CTD PMID:23671600 benzene multiple interactions EXP 6480464 Benzene inhibits the reaction [INS results in increased phosphorylation of AKT1 protein] CTD PMID:30346588 benzo[a]pyrene decreases expression ISO RGD:732909 6480464 Benzo(a)pyrene results in decreased expression of AKT1 mRNA CTD PMID:20106945 benzo[a]pyrene affects methylation ISO RGD:732909 6480464 Benzo(a)pyrene affects the methylation of AKT1 intron CTD PMID:30157460 benzo[a]pyrene multiple interactions ISO RGD:732909 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Benzo(a)pyrene] results in decreased phosphorylation of AKT1 protein more ... CTD PMID:24685774 , PMID:30726812 benzo[a]pyrene increases phosphorylation ISO RGD:732909 6480464 Benzo(a)pyrene results in increased phosphorylation of AKT1 protein CTD PMID:19181443 , PMID:24685774 benzo[a]pyrene decreases phosphorylation ISO RGD:732909 6480464 Benzo(a)pyrene results in decreased phosphorylation of AKT1 protein CTD PMID:24431215 , PMID:30726812 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:732909 6480464 7 more ... CTD PMID:19801633 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RGD:732909 6480464 7 more ... CTD PMID:28529061 , PMID:30011042 benzo[a]pyrene diol epoxide I decreases phosphorylation ISO RGD:732909 6480464 7 more ... CTD PMID:24431215 benzo[a]pyrene diol epoxide I increases phosphorylation EXP 6480464 7 more ... CTD PMID:21501596 benzo[a]pyrene diol epoxide I multiple interactions EXP 6480464 AG 1879 inhibits the reaction [7 more ... CTD PMID:21501596 benzo[e]pyrene decreases methylation ISO RGD:732909 6480464 benzo(e)pyrene results in decreased methylation of AKT1 intron CTD PMID:30157460 benzophenanthridine decreases expression ISO RGD:732909 6480464 Benzophenanthridines analog results in decreased expression of AKT1 mRNA CTD PMID:23117580 berberine increases phosphorylation ISO RGD:732909 6480464 Berberine results in increased phosphorylation of AKT1 protein CTD PMID:23954465 berberine multiple interactions ISO RGD:2081 6480464 Berberine inhibits the reaction [Thioacetamide results in increased phosphorylation of AKT1 protein] CTD PMID:30138605 berberine multiple interactions ISO RGD:732909 6480464 Berberine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:23954465 beta-carotene decreases phosphorylation ISO RGD:732909 6480464 beta Carotene results in decreased phosphorylation of AKT1 protein CTD PMID:26733226 beta-cyclodextrin multiple interactions ISO RGD:732909 6480464 betadex inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 beta-D-glucosamine affects phosphorylation ISO RGD:732909 6480464 Glucosamine analog affects the phosphorylation of AKT1 protein CTD PMID:18080321 beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein], OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] CTD PMID:30602124 beta-D-glucosamine multiple interactions ISO RGD:732909 6480464 Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein], Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] CTD PMID:18080321 , PMID:18340449 betulinic acid increases phosphorylation ISO RGD:732909 6480464 betulinic acid results in increased phosphorylation of AKT1 protein CTD PMID:16077934 betulinic acid multiple interactions ISO RGD:732909 6480464 4-((3-bromophenyl)amino)-6, 7-dimethoxyquinazoline inhibits the reaction [betulinic acid results in increased phosphorylation of AKT1 protein] CTD PMID:16077934 bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] CTD PMID:15806154 bicalutamide multiple interactions ISO RGD:732909 6480464 bicalutamide inhibits the reaction [Metribolone results in increased phosphorylation of AKT1 protein] CTD PMID:17325745 bilirubin IXalpha multiple interactions ISO RGD:732909 6480464 Bilirubin inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] CTD PMID:18215737 biliverdin multiple interactions ISO RGD:732909 6480464 Biliverdine inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] CTD PMID:18215737 bis(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 Diethylhexyl Phthalate results in increased phosphorylation of AKT1 protein CTD PMID:24804967 bis(2-ethylhexyl) phthalate affects expression ISO RGD:2081 6480464 Diethylhexyl Phthalate affects the expression of AKT1 mRNA CTD PMID:29777495 bis(2-ethylhexyl) phthalate decreases phosphorylation ISO RGD:732909 6480464 Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein CTD PMID:31163220 bis(2-ethylhexyl) phthalate decreases phosphorylation ISO RGD:2081 6480464 Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein CTD PMID:22610992 , PMID:25280772 bis(2-ethylhexyl) phthalate increases expression ISO RGD:732909 6480464 Diethylhexyl Phthalate results in increased expression of AKT1 mRNA CTD PMID:23793038 bis(2-ethylhexyl) phthalate increases phosphorylation ISO RGD:732909 6480464 Diethylhexyl Phthalate results in increased phosphorylation of AKT1 protein CTD PMID:19956873 , PMID:30543897 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AKT1 mRNA] more ... CTD PMID:19956873 more ... bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:2081 6480464 [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:21911000 more ... bisdemethoxycurcumin increases phosphorylation EXP 6480464 bis(4-hydroxycinnamoyl)methane results in increased phosphorylation of AKT1 protein CTD PMID:17535857 bisdemethoxycurcumin multiple interactions EXP 6480464 AKT1 protein affects the reaction [bis(4-hydroxycinnamoyl)methane results in increased expression of HMOX1 mRNA] CTD PMID:17535857 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of AKT1 mRNA more ... CTD PMID:20488778 more ... bisphenol A increases acetylation ISO RGD:2081 6480464 bisphenol A results in increased acetylation of AKT1 protein CTD PMID:31332466 bisphenol A increases expression ISO RGD:2081 6480464 bisphenol A results in increased expression of AKT1 mRNA CTD PMID:27208089 , PMID:27539358 bisphenol A decreases phosphorylation ISO RGD:2081 6480464 bisphenol A results in decreased phosphorylation of AKT1 protein CTD PMID:25112833 more ... bisphenol A decreases expression ISO RGD:2081 6480464 bisphenol A results in decreased expression of AKT1 mRNA CTD PMID:27296223 bisphenol A increases phosphorylation ISO RGD:2081 6480464 bisphenol A results in increased phosphorylation of AKT1 protein CTD PMID:20096755 more ... bisphenol A affects expression ISO RGD:2081 6480464 bisphenol A affects the expression of AKT1 mRNA CTD PMID:25181051 , PMID:29777495 bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of AKT1 protein CTD PMID:15659569 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AKT1 mRNA CTD PMID:26063408 bisphenol A decreases phosphorylation EXP 6480464 bisphenol A results in decreased phosphorylation of AKT1 protein CTD PMID:25637671 more ... bisphenol A increases phosphorylation ISO RGD:732909 6480464 bisphenol A results in increased phosphorylation of AKT1 protein CTD PMID:19956873 more ... bisphenol A increases activity ISO RGD:732909 6480464 bisphenol A results in increased activity of AKT1 protein CTD PMID:22692793 , PMID:27038254 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AKT1 mRNA, bisphenol A results in decreased expression of AKT1 protein CTD PMID:23376180 bisphenol A increases expression ISO RGD:732909 6480464 bisphenol A results in increased expression of AKT1 protein CTD PMID:21890461 , PMID:23222814 bisphenol A multiple interactions ISO RGD:732909 6480464 1-(4-(6-bromobenzo(1 more ... CTD PMID:18767177 more ... bisphenol A multiple interactions ISO RGD:2081 6480464 [bisphenol A co-treated with 4-nonylphenol] results in increased expression of AKT1 mRNA more ... CTD PMID:23424204 more ... Bisphenol B increases acetylation ISO RGD:2081 6480464 bisphenol B results in increased acetylation of AKT1 protein CTD PMID:31332466 bisphenol F decreases expression ISO RGD:2081 6480464 4, 4'-bisphenol F results in decreased expression of AKT1 mRNA CTD PMID:26186136 bisphenol F increases acetylation ISO RGD:2081 6480464 bisphenol F results in increased acetylation of AKT1 protein CTD PMID:31332466 bleomycin A2 increases phosphorylation EXP 6480464 Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607 , PMID:26520185 BMS-754807 decreases phosphorylation ISO RGD:732909 6480464 BMS 754807 results in decreased phosphorylation of AKT1 protein CTD PMID:24986516 BMS-754807 multiple interactions ISO RGD:732909 6480464 BMS 754807 inhibits the reaction [palbociclib results in increased phosphorylation of AKT1 protein] CTD PMID:24986516 bortezomib multiple interactions ISO RGD:732909 6480464 [alvocidib co-treated with Bortezomib] results in decreased expression of AKT1 protein modified form more ... CTD PMID:15039284 more ... bortezomib decreases expression ISO RGD:732909 6480464 Bortezomib results in decreased expression of AKT1 protein modified form CTD PMID:18701494 , PMID:19261616 bortezomib decreases activity ISO RGD:732909 6480464 Bortezomib results in decreased activity of AKT1 protein CTD PMID:18445700 bosutinib decreases phosphorylation EXP 6480464 bosutinib results in decreased phosphorylation of AKT1 protein CTD PMID:17129604 bosutinib decreases expression EXP 6480464 bosutinib results in decreased expression of AKT1 protein CTD PMID:17129604 brefeldin A multiple interactions ISO RGD:2081 6480464 Brefeldin A inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] CTD PMID:15525798 brefeldin A decreases phosphorylation ISO RGD:2081 6480464 Brefeldin A results in decreased phosphorylation of AKT1 protein CTD PMID:24090963 bufalin multiple interactions ISO RGD:732909 6480464 bufalin results in increased phosphorylation of and results in decreased expression of AKT1 protein CTD PMID:23949904 butan-1-ol multiple interactions ISO RGD:732909 6480464 1-Butanol inhibits the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:15919668 more ... butan-1-ol multiple interactions ISO RGD:2081 6480464 1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] more ... CTD PMID:14769825 more ... butan-1-ol multiple interactions EXP 6480464 1-Butanol inhibits the reaction [Phospholipids results in increased phosphorylation of AKT1 protein] CTD PMID:15956784 butein decreases phosphorylation ISO RGD:732909 6480464 butein results in decreased phosphorylation of AKT1 protein CTD PMID:20696233 Butylbenzyl phthalate multiple interactions ISO RGD:732909 6480464 HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of AKT1 protein] CTD PMID:22552774 Butylbenzyl phthalate affects phosphorylation ISO RGD:732909 6480464 butylbenzyl phthalate affects the phosphorylation of AKT1 protein CTD PMID:29864457 Butylbenzyl phthalate affects phosphorylation ISO RGD:2081 6480464 butylbenzyl phthalate affects the phosphorylation of AKT1 protein CTD PMID:31319113 Butylbenzyl phthalate increases phosphorylation ISO RGD:732909 6480464 butylbenzyl phthalate results in increased phosphorylation of AKT1 protein CTD PMID:22552774 butyric acid decreases phosphorylation ISO RGD:732909 6480464 Butyric Acid results in decreased phosphorylation of AKT1 protein CTD PMID:28600122 butyric acid multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of AKT1 protein] CTD PMID:28600122 Cacalol decreases phosphorylation ISO RGD:732909 6480464 cacalol results in decreased phosphorylation of AKT1 protein CTD PMID:20665104 cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of AKT1 protein CTD PMID:24449419 cadmium atom increases phosphorylation ISO RGD:732909 6480464 Cadmium results in increased phosphorylation of AKT1 protein CTD PMID:14499349 more ... cadmium atom decreases phosphorylation ISO RGD:732909 6480464 Cadmium results in decreased phosphorylation of AKT1 protein CTD PMID:26187450 cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of AKT1 mRNA CTD PMID:26187450 cadmium atom increases activity ISO RGD:2081 6480464 Cadmium results in increased activity of AKT1 protein CTD PMID:18573614 cadmium atom multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein], Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] CTD PMID:27658547 cadmium atom increases phosphorylation ISO RGD:2081 6480464 Cadmium results in increased phosphorylation of AKT1 protein CTD PMID:27658547 cadmium atom multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] more ... CTD PMID:24449419 cadmium atom multiple interactions ISO RGD:732909 6480464 acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17125913 more ... cadmium dichloride multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased cleavage of AKT1 protein] more ... CTD PMID:17125913 more ... cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of AKT1 protein CTD PMID:23948867 more ... cadmium dichloride increases phosphorylation ISO RGD:2081 6480464 Cadmium Chloride results in increased phosphorylation of AKT1 protein CTD PMID:19233221 more ... cadmium dichloride increases phosphorylation ISO RGD:732909 6480464 Cadmium Chloride results in increased phosphorylation of AKT1 protein CTD PMID:17125913 more ... cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:21544200 more ... cadmium dichloride multiple interactions ISO RGD:2081 6480464 1 more ... CTD PMID:18021293 more ... caffeine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Caffeine results in increased phosphorylation of AKT1 protein] more ... CTD PMID:18201823 , PMID:21081844 caffeine affects expression ISO RGD:2081 6480464 Caffeine affects the expression of AKT1 mRNA CTD PMID:30528684 caffeine multiple interactions EXP 6480464 Caffeine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] CTD PMID:22974838 caffeine decreases expression ISO RGD:2081 6480464 Caffeine results in decreased expression of AKT1 mRNA, Caffeine results in decreased expression of AKT1 protein modified form CTD PMID:21081844 , PMID:29966748 caffeine decreases phosphorylation EXP 6480464 Caffeine results in decreased phosphorylation of AKT1 protein CTD PMID:15126379 caffeine decreases phosphorylation ISO RGD:732909 6480464 Caffeine results in decreased phosphorylation of AKT1 protein CTD PMID:21081844 , PMID:21561856 caffeine increases phosphorylation ISO RGD:732909 6480464 Caffeine results in increased phosphorylation of AKT1 protein CTD PMID:18201823 caffeine decreases expression ISO RGD:732909 6480464 Caffeine results in decreased expression of AKT1 protein modified form CTD PMID:21081844 caffeine decreases response to substance ISO RGD:732909 6480464 AKT1 results in decreased susceptibility to Caffeine CTD PMID:21561856 Calcimycin multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Calcimycin results in increased phosphorylation of AKT1 protein] CTD PMID:10679475 Calcimycin increases phosphorylation EXP 6480464 Calcimycin results in increased phosphorylation of AKT1 protein CTD PMID:10679475 calcitriol multiple interactions ISO RGD:732909 6480464 Calcitriol inhibits the reaction [IL2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:15879110 calcium atom affects abundance ISO RGD:732909 6480464 AKT1 protein affects the abundance of Calcium CTD PMID:16094411 calcium atom affects expression ISO RGD:2081 6480464 Calcium affects the expression of AKT1 mRNA CTD PMID:15913539 calcium atom multiple interactions ISO RGD:732909 6480464 [Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein more ... CTD PMID:16236484 , PMID:28634229 calcium atom affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to Calcium CTD PMID:16094411 calcium(0) affects abundance ISO RGD:732909 6480464 AKT1 protein affects the abundance of Calcium CTD PMID:16094411 calcium(0) affects expression ISO RGD:2081 6480464 Calcium affects the expression of AKT1 mRNA CTD PMID:15913539 calcium(0) multiple interactions ISO RGD:732909 6480464 [Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein more ... CTD PMID:16236484 , PMID:28634229 calcium(0) affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to Calcium CTD PMID:16094411 calyculin a multiple interactions ISO RGD:732909 6480464 calyculin A inhibits the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] CTD PMID:18790744 camptothecin affects phosphorylation ISO RGD:732909 6480464 Camptothecin affects the phosphorylation of AKT1 protein CTD PMID:24095863 camptothecin increases phosphorylation ISO RGD:732909 6480464 Camptothecin results in increased phosphorylation of AKT1 protein CTD PMID:30851366 camptothecin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Camptothecin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:24095863 , PMID:30851366 candesartan decreases phosphorylation ISO RGD:2081 6480464 candesartan results in decreased phosphorylation of AKT1 protein CTD PMID:17922026 cantharidin increases phosphorylation ISO RGD:732909 6480464 Cantharidin results in increased phosphorylation of AKT1 protein CTD PMID:27113412 capsaicin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:19059400 more ... capsaicin increases phosphorylation ISO RGD:732909 6480464 Capsaicin results in increased phosphorylation of AKT1 protein CTD PMID:17979524 more ... capsaicin increases phosphorylation ISO RGD:2081 6480464 Capsaicin results in increased phosphorylation of AKT1 protein CTD PMID:17084039 capsaicin increases expression ISO RGD:2081 6480464 Capsaicin results in increased expression of AKT1 protein modified form CTD PMID:17084039 capsaicin increases activity ISO RGD:2081 6480464 Capsaicin results in increased activity of AKT1 protein CTD PMID:16360265 capsaicin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein], [Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein CTD PMID:19011674 capsaicin multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein, EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein] CTD PMID:20660715 capsazepine multiple interactions ISO RGD:732909 6480464 capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein] CTD PMID:19059400 captan multiple interactions EXP 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein, [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 carbamazepine affects expression ISO RGD:732909 6480464 Carbamazepine affects the expression of AKT1 mRNA CTD PMID:24752500 CARBENOXOLONE affects expression ISO RGD:732909 6480464 Carbenoxolone affects the expression of AKT1 mRNA CTD PMID:23678415 carbon monoxide multiple interactions EXP 6480464 AKT1 protein affects the reaction [Carbon Monoxide results in increased localization of NRF1 protein] more ... CTD PMID:17179207 more ... carbon monoxide multiple interactions ISO RGD:732909 6480464 Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] CTD PMID:18215737 carbon monoxide multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Carbon Monoxide results in increased expression of ADIPOQ protein] which results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17179207 , PMID:19356108 carbon monoxide increases phosphorylation EXP 6480464 Carbon Monoxide results in increased phosphorylation of AKT1 protein CTD PMID:18845810 carbon nanotube increases activity EXP 6480464 Nanotubes, Carbon results in increased activity of AKT1 protein CTD PMID:29112861 carbonyl cyanide p-trifluoromethoxyphenylhydrazone increases phosphorylation EXP 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of AKT1 protein CTD PMID:19901985 carboplatin multiple interactions EXP 6480464 Pravastatin inhibits the reaction [Carboplatin results in increased activity of and results in increased phosphorylation of AKT1 protein] CTD PMID:18483861 carmustine decreases phosphorylation ISO RGD:2081 6480464 Carmustine results in decreased phosphorylation of AKT1 protein CTD PMID:19860839 carmustine multiple interactions ISO RGD:2081 6480464 LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein] CTD PMID:19860839 carmustine affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to Carmustine CTD PMID:18430789 carnosic acid increases phosphorylation ISO RGD:732909 6480464 salvin results in increased phosphorylation of AKT1 protein CTD PMID:25271104 carnosic acid decreases phosphorylation ISO RGD:732909 6480464 salvin results in decreased phosphorylation of AKT1 protein CTD PMID:25178877 carnosine multiple interactions ISO RGD:2081 6480464 Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of AKT1 protein] CTD PMID:28266762 carrageenan increases phosphorylation EXP 6480464 Carrageenan results in increased phosphorylation of AKT1 protein CTD PMID:26418808 carrageenan multiple interactions EXP 6480464 fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein] CTD PMID:26418808 carvedilol increases phosphorylation EXP 6480464 carvedilol results in increased phosphorylation of AKT1 protein CTD PMID:27288437 carvedilol increases phosphorylation ISO RGD:2081 6480464 carvedilol results in increased phosphorylation of AKT1 protein CTD PMID:27288437 casticin decreases expression EXP 6480464 casticin results in decreased expression of AKT1 protein CTD PMID:28444820 celastrol decreases phosphorylation ISO RGD:732909 6480464 tripterine results in decreased phosphorylation of AKT1 protein CTD PMID:21466843 celastrol multiple interactions ISO RGD:2081 6480464 PTEN protein promotes the reaction [tripterine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]], tripterine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein] CTD PMID:24111524 celastrol increases phosphorylation ISO RGD:2081 6480464 tripterine results in increased phosphorylation of AKT1 protein CTD PMID:25903958 celecoxib multiple interactions ISO RGD:732909 6480464 [Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of AKT1 protein more ... CTD PMID:10753955 more ... celecoxib decreases expression EXP 6480464 Celecoxib results in decreased expression of AKT1 protein CTD PMID:15570007 celecoxib affects phosphorylation EXP 6480464 Celecoxib affects the phosphorylation of AKT1 protein CTD PMID:15570007 celecoxib decreases activity ISO RGD:732909 6480464 Celecoxib results in decreased activity of AKT1 protein CTD PMID:17285134 celecoxib decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Celecoxib CTD PMID:10753955 , PMID:19201774 celecoxib decreases phosphorylation ISO RGD:732909 6480464 Celecoxib analog results in decreased phosphorylation of AKT1 protein, Celecoxib results in decreased phosphorylation of AKT1 protein CTD PMID:12000750 more ... celecoxib decreases expression ISO RGD:732909 6480464 Celecoxib results in decreased expression of AKT1 protein CTD PMID:14654083 celecoxib increases phosphorylation ISO RGD:732909 6480464 Celecoxib analog results in increased phosphorylation of AKT1 protein, Celecoxib results in increased phosphorylation of AKT1 protein CTD PMID:15499625 , PMID:17270149 celecoxib multiple interactions ISO RGD:2081 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of AKT1 protein more ... CTD PMID:17908994 , PMID:19201774 ceric oxide decreases expression ISO RGD:732909 6480464 ceric oxide analog results in decreased expression of AKT1 mRNA CTD PMID:24821434 ceruletide multiple interactions EXP 6480464 (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein], [KRAS protein mutant form co-treated with Ceruletide] results in increased phosphorylation of AKT1 protein CTD PMID:26390243 chaetoglobosin A increases phosphorylation ISO RGD:2081 6480464 chaetoglobosins results in increased phosphorylation of AKT1 protein CTD PMID:18040759 chaetoglobosin A multiple interactions ISO RGD:2081 6480464 wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of AKT1 protein] CTD PMID:18040759 Chicoric acid multiple interactions ISO RGD:2081 6480464 chicoric acid inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:24244361 chitosan multiple interactions ISO RGD:2081 6480464 [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of AKT1 protein] CTD PMID:28732690 chloroethene increases phosphorylation EXP 6480464 Vinyl Chloride metabolite results in increased phosphorylation of AKT1 protein CTD PMID:26962056 chlorohydrocarbon multiple interactions ISO RGD:732909 6480464 wortmannin inhibits the reaction [Hydrocarbons, Chlorinated results in increased phosphorylation of AKT1 protein] CTD PMID:14757120 chlorohydrocarbon increases phosphorylation ISO RGD:732909 6480464 Hydrocarbons, Chlorinated results in increased phosphorylation of AKT1 protein CTD PMID:14757120 chloroquine multiple interactions ISO RGD:732909 6480464 Chloroquine inhibits the reaction [formosanin C results in decreased phosphorylation of AKT1 protein] CTD PMID:27180204 chlorpromazine decreases phosphorylation ISO RGD:2081 6480464 Chlorpromazine results in decreased phosphorylation of AKT1 protein CTD PMID:17512020 chlorpyrifos multiple interactions EXP 6480464 [APOE protein results in increased susceptibility to Chlorpyrifos] which results in decreased phosphorylation of AKT1 protein CTD PMID:29404631 cholesterol multiple interactions EXP 6480464 Cholesterol inhibits the reaction [irbesartan results in increased expression of AKT1 protein] CTD PMID:19028402 cholesterol multiple interactions ISO RGD:732909 6480464 Cholesterol results in increased expression of and results in increased phosphorylation of AKT1 protein CTD PMID:19672739 cholic acid multiple interactions EXP 6480464 Cholic Acid results in increased activity of and results in increased phosphorylation of AKT1 protein, Diethylnitrosamine inhibits the reaction [Cholic Acid results in increased activity of and results in increased phosphorylation of AKT1 protein] CTD PMID:27151938 chromium atom multiple interactions ISO RGD:2081 6480464 [Niacin co-treated with Chromium] results in increased phosphorylation of AKT1 protein CTD PMID:19027847 chromium atom multiple interactions EXP 6480464 Chromium inhibits the reaction [Dietary Fats results in decreased phosphorylation of AKT1 protein] CTD PMID:20513351 chromium(6+) multiple interactions ISO RGD:732909 6480464 AKT1 protein affects the reaction [Vanadates inhibits the reaction [chromium hexavalent ion affects the localization of CDKN1B protein]] more ... CTD PMID:19377290 , PMID:25448439 chromium(6+) multiple interactions ISO RGD:2081 6480464 chromium hexavalent ion results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:28911802 chromium(6+) increases phosphorylation ISO RGD:732909 6480464 chromium hexavalent ion results in increased phosphorylation of AKT1 protein CTD PMID:25448439 chromones affects binding ISO RGD:732909 6480464 [Chromones analog binds to cuprous chloride] which binds to AKT1 protein CTD PMID:16789737 chromones multiple interactions ISO RGD:732909 6480464 [Chromones analog binds to cuprous chloride] which results in decreased activity of AKT1 protein CTD PMID:16789737 chrysin multiple interactions ISO RGD:732909 6480464 BCL2 protein inhibits the reaction [chrysin results in decreased phosphorylation of and results in decreased activity of AKT1 protein] more ... CTD PMID:16215670 , PMID:24122885 chrysin decreases phosphorylation ISO RGD:732909 6480464 chrysin results in decreased phosphorylation of AKT1 protein CTD PMID:18455702 more ... chrysophanol decreases phosphorylation ISO RGD:732909 6480464 chrysophanic acid results in decreased phosphorylation of AKT1 protein CTD PMID:30300626 cilostazol multiple interactions ISO RGD:732909 6480464 cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:12807996 cilostazol increases phosphorylation ISO RGD:2081 6480464 cilostazol results in increased phosphorylation of AKT1 protein CTD PMID:15978173 cilostazol increases phosphorylation ISO RGD:732909 6480464 cilostazol results in increased phosphorylation of AKT1 protein CTD PMID:18556572 ciprofloxacin increases phosphorylation ISO RGD:732909 6480464 Ciprofloxacin results in increased phosphorylation of AKT1 protein CTD PMID:26947806 cisplatin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[MIR21 mRNA results in decreased susceptibility to Cisplatin] which results in increased phosphorylation of AKT1 protein] more ... CTD PMID:14755253 more ... cisplatin increases phosphorylation ISO RGD:2081 6480464 Cisplatin results in increased phosphorylation of AKT1 protein CTD PMID:30125553 cisplatin decreases phosphorylation EXP 6480464 Cisplatin results in decreased phosphorylation of AKT1 protein CTD PMID:21074548 , PMID:24823295 cisplatin affects response to substance ISO RGD:732909 6480464 AKT1 polymorphism affects the susceptibility to Cisplatin CTD PMID:22901187 cisplatin decreases phosphorylation ISO RGD:732909 6480464 Cisplatin results in decreased phosphorylation of AKT1 protein CTD PMID:14755253 more ... cisplatin decreases expression ISO RGD:732909 6480464 [Cisplatin results in decreased expression of TP63 protein alternative form] which results in decreased expression of AKT1 more ... CTD PMID:21266360 cisplatin decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Cisplatin, AKT1 results in decreased susceptibility to Cisplatin CTD PMID:21266360 more ... citalopram multiple interactions ISO RGD:732909 6480464 Citalopram inhibits the reaction [convulxin results in increased phosphorylation of AKT1 protein] CTD PMID:30592962 Citreoviridin multiple interactions ISO RGD:2081 6480464 Rosiglitazone inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:31419397 Citreoviridin decreases phosphorylation ISO RGD:2081 6480464 citreoviridin results in decreased phosphorylation of AKT1 protein CTD PMID:31419397 Citreoviridin multiple interactions EXP 6480464 Sodium Selenite inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein], Thiamine inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein] CTD PMID:31419397 Citreoviridin decreases phosphorylation EXP 6480464 citreoviridin results in decreased phosphorylation of AKT1 protein CTD PMID:31419397 clenbuterol multiple interactions ISO RGD:2081 6480464 Clenbuterol inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] CTD PMID:16339297 clozapine increases expression ISO RGD:732909 6480464 Clozapine results in increased expression of AKT1 mRNA, Clozapine results in increased expression of AKT1 protein CTD PMID:19440698 clozapine decreases expression ISO RGD:2081 6480464 Clozapine results in decreased expression of AKT1 mRNA CTD PMID:15860345 clozapine increases phosphorylation ISO RGD:732909 6480464 Clozapine results in increased phosphorylation of AKT1 protein CTD PMID:19440698 cobalt dichloride multiple interactions ISO RGD:732909 6480464 AKT1 protein affects the reaction [cobaltous chloride results in increased secretion of CXCL8 protein] CTD PMID:17082639 cobalt dichloride increases phosphorylation ISO RGD:732909 6480464 cobaltous chloride results in increased phosphorylation of AKT1 protein CTD PMID:27297870 cobalt dichloride decreases phosphorylation EXP 6480464 cobaltous chloride results in decreased phosphorylation of AKT1 protein CTD PMID:23684559 cobalt dichloride decreases expression ISO RGD:732909 6480464 cobaltous chloride results in decreased expression of AKT1 mRNA CTD PMID:19320972 cocaine affects expression ISO RGD:2081 6480464 Cocaine affects the expression of AKT1 mRNA CTD PMID:20187946 cocaine multiple interactions EXP 6480464 [Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein CTD PMID:25933444 cocaine increases phosphorylation EXP 6480464 Cocaine results in increased phosphorylation of AKT1 protein CTD PMID:25933444 cocaine increases phosphorylation ISO RGD:2081 6480464 Cocaine results in increased phosphorylation of AKT1 protein CTD PMID:18702665 cocaine multiple interactions ISO RGD:2081 6480464 Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein] CTD PMID:18702665 coenzyme Q10 multiple interactions ISO RGD:2081 6480464 coenzyme Q10 inhibits the reaction [Atorvastatin results in decreased phosphorylation of AKT1 protein], coenzyme Q10 inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein] CTD PMID:27087047 , PMID:27345130 Colforsin dapropate hydrochloride multiple interactions ISO RGD:2081 6480464 Colforsin inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] CTD PMID:16339297 colistin decreases phosphorylation ISO RGD:2081 6480464 Colistin results in decreased phosphorylation of AKT1 protein CTD PMID:28465020 colistin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein]], rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein] CTD PMID:28465020 copper atom multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:16648635 more ... copper atom decreases phosphorylation EXP 6480464 Copper analog results in decreased phosphorylation of AKT1 protein CTD PMID:22000994 copper(0) multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Clioquinol co-treated with Copper] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:16648635 more ... copper(0) decreases phosphorylation EXP 6480464 Copper analog results in decreased phosphorylation of AKT1 protein CTD PMID:22000994 copper(I) chloride affects binding ISO RGD:732909 6480464 [Chromones analog binds to cuprous chloride] which binds to AKT1 protein CTD PMID:16789737 copper(I) chloride multiple interactions ISO RGD:732909 6480464 [Chromones analog binds to cuprous chloride] which results in decreased activity of AKT1 protein CTD PMID:16789737 copper(II) sulfate multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Copper Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:15001399 more ... copper(II) sulfate increases phosphorylation ISO RGD:732909 6480464 Copper Sulfate results in increased phosphorylation of AKT1 protein CTD PMID:24933099 coptisine decreases phosphorylation ISO RGD:732909 6480464 coptisine analog results in decreased phosphorylation of AKT1 protein CTD PMID:30472432 corticosterone decreases expression ISO RGD:2081 6480464 Corticosterone results in decreased expression of AKT1 mRNA CTD PMID:29966748 cortisol decreases phosphorylation ISO RGD:2081 6480464 Hydrocortisone results in decreased phosphorylation of AKT1 protein CTD PMID:15187100 crizotinib multiple interactions ISO RGD:732909 6480464 EGF protein inhibits the reaction [crizotinib results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:22553343 , PMID:22729845 crizotinib decreases phosphorylation ISO RGD:732909 6480464 crizotinib results in decreased phosphorylation of AKT1 protein CTD PMID:22553343 , PMID:22729845 crocidolite asbestos multiple interactions ISO RGD:2081 6480464 arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein], ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein] CTD PMID:14627993 crocidolite asbestos increases phosphorylation EXP 6480464 Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein CTD PMID:15897870 crocidolite asbestos increases activity ISO RGD:732909 6480464 Asbestos, Crocidolite results in increased activity of AKT1 protein CTD PMID:17322126 crocidolite asbestos increases expression ISO RGD:732909 6480464 Asbestos, Crocidolite results in increased expression of AKT1 mRNA CTD PMID:17322126 crocidolite asbestos multiple interactions ISO RGD:732909 6480464 Asbestos, Crocidolite results in decreased expression of and results in decreased phosphorylation of AKT1 protein more ... CTD PMID:17191120 , PMID:17322126 crocidolite asbestos increases phosphorylation ISO RGD:2081 6480464 Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein CTD PMID:14627993 cucurbitacin E multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [cucurbitacin E affects the phosphorylation of AKT1 protein] CTD PMID:27106530 cucurbitacin E affects phosphorylation ISO RGD:732909 6480464 cucurbitacin E affects the phosphorylation of AKT1 protein CTD PMID:27106530 curcumin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:16219905 more ... curcumin affects phosphorylation EXP 6480464 Curcumin affects the phosphorylation of AKT1 protein CTD PMID:27208389 curcumin decreases expression ISO RGD:732909 6480464 Curcumin analog results in decreased expression of AKT1 mRNA, Curcumin results in decreased expression of AKT1 protein CTD PMID:24211270 , PMID:26409325 curcumin decreases phosphorylation ISO RGD:732909 6480464 Curcumin results in decreased phosphorylation of AKT1 protein CTD PMID:17289836 more ... curcumin increases expression ISO RGD:732909 6480464 Curcumin results in increased expression of AKT1 protein CTD PMID:23222814 curcumin increases phosphorylation ISO RGD:732909 6480464 Curcumin results in increased phosphorylation of AKT1 protein CTD PMID:20938987 curcumin multiple interactions ISO RGD:2081 6480464 AKT1 protein affects the reaction [Curcumin results in increased expression of AKR1B1 mRNA] more ... CTD PMID:17372590 more ... curcumin increases phosphorylation EXP 6480464 Curcumin results in increased phosphorylation of AKT1 protein CTD PMID:17535857 curcumin decreases phosphorylation EXP 6480464 Curcumin results in decreased phosphorylation of AKT1 protein CTD PMID:18006147 curcumin multiple interactions EXP 6480464 AKT1 protein affects the reaction [Curcumin results in increased expression of HMOX1 mRNA] CTD PMID:17535857 curcumin decreases activity ISO RGD:732909 6480464 Curcumin results in decreased activity of AKT1 protein CTD PMID:16023083 cyanidin 3-O-beta-D-glucoside multiple interactions EXP 6480464 cyanidin 3-O-glucoside inhibits the reaction [7 more ... CTD PMID:21501596 cycloheximide multiple interactions ISO RGD:2081 6480464 Cycloheximide inhibits the reaction [[Hydrogen Peroxide co-treated with sodium arsenite] results in increased phosphorylation of AKT1 protein] CTD PMID:12472888 cycloheximide increases phosphorylation ISO RGD:732909 6480464 Cycloheximide results in increased phosphorylation of AKT1 protein CTD PMID:28634229 cyclophosphamide multiple interactions ISO RGD:2081 6480464 Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein more ... CTD PMID:19996110 , PMID:25446862 cyclophosphamide decreases expression ISO RGD:2081 6480464 Cyclophosphamide results in decreased expression of AKT1 protein CTD PMID:25446862 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Calcimycin results in increased phosphorylation of AKT1 protein], Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of AKT1 protein] CTD PMID:10679475 cyclosporin A decreases expression ISO RGD:732909 6480464 Cyclosporine results in decreased expression of AKT1 mRNA CTD PMID:20106945 , PMID:25562108 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of AKT1 mRNA CTD PMID:19770486 cyhalothrin increases activity EXP 6480464 cyhalothrin results in increased activity of AKT1 CTD PMID:26969072 cypermethrin decreases expression ISO RGD:2081 6480464 cypermethrin results in decreased expression of AKT1 mRNA CTD PMID:22528246 cypermethrin increases expression ISO RGD:732909 6480464 cypermethrin results in increased expression of AKT1 mRNA CTD PMID:27704156 D-glucose multiple interactions EXP 6480464 [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein more ... CTD PMID:15806154 more ... D-glucose increases phosphorylation ISO RGD:2081 6480464 Glucose results in increased phosphorylation of AKT1 protein CTD PMID:23159718 more ... D-glucose decreases phosphorylation ISO RGD:732909 6480464 Glucose results in decreased phosphorylation of AKT1 protein CTD PMID:21333731 more ... D-glucose decreases phosphorylation ISO RGD:2081 6480464 Glucose results in decreased phosphorylation of AKT1 protein CTD PMID:23453443 more ... D-glucose increases phosphorylation ISO RGD:732909 6480464 Glucose results in increased phosphorylation of AKT1 protein CTD PMID:21333731 D-glucose increases response to substance EXP 6480464 AKT1 protein mutant form results in increased susceptibility to Glucose deficiency CTD PMID:15806154 D-glucose decreases expression ISO RGD:2081 6480464 Glucose results in decreased expression of AKT1 protein modified form CTD PMID:18004065 D-glucose multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:16385087 more ... D-glucose multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:18004065 more ... dactolisib decreases phosphorylation ISO RGD:732909 6480464 dactolisib results in decreased phosphorylation of AKT1 protein CTD PMID:21464613 more ... dactolisib multiple interactions ISO RGD:732909 6480464 dactolisib inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein], PD 0325901 promotes the reaction [dactolisib results in decreased phosphorylation of AKT1 protein] CTD PMID:22415236 , PMID:24758408 dactolisib decreases expression ISO RGD:732909 6480464 dactolisib results in decreased expression of AKT1 protein modified form CTD PMID:19435893 dactolisib decreases phosphorylation EXP 6480464 dactolisib results in decreased phosphorylation of AKT1 protein CTD PMID:22949526 dactolisib multiple interactions EXP 6480464 dactolisib inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein], LEPR affects the reaction [dactolisib results in decreased phosphorylation of AKT1 protein] CTD PMID:22949526 DAPT multiple interactions ISO RGD:732909 6480464 1 more ... CTD PMID:31348943 daunorubicin decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Daunorubicin CTD PMID:22252735 deferiprone multiple interactions ISO RGD:2081 6480464 deferiprone inhibits the reaction [ferrous sulfate results in increased phosphorylation of AKT1 protein], deferiprone inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein] CTD PMID:17172471 Deguelin affects phosphorylation ISO RGD:732909 6480464 deguelin affects the phosphorylation of AKT1 protein CTD PMID:25322282 Deguelin decreases phosphorylation ISO RGD:732909 6480464 deguelin results in decreased phosphorylation of AKT1 protein CTD PMID:18593368 more ... Deguelin decreases expression ISO RGD:732909 6480464 deguelin metabolite results in decreased expression of AKT1 protein, deguelin results in decreased expression of AKT1 protein CTD PMID:19139008 , PMID:19336726 Deguelin increases phosphorylation EXP 6480464 deguelin results in increased phosphorylation of AKT1 protein CTD PMID:19901985 Deguelin multiple interactions ISO RGD:732909 6480464 deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17015749 Deguelin decreases phosphorylation EXP 6480464 deguelin results in decreased phosphorylation of AKT1 protein CTD PMID:16288123 demethoxycurcumin increases phosphorylation EXP 6480464 demethoxycurcumin results in increased phosphorylation of AKT1 protein CTD PMID:17535857 demethoxycurcumin multiple interactions EXP 6480464 AKT1 protein affects the reaction [demethoxycurcumin results in increased expression of HMOX1 mRNA] CTD PMID:17535857 demethoxyfumitremorgin C decreases expression ISO RGD:732909 6480464 demethoxyfumitremorgin C results in decreased expression of AKT1 protein CTD PMID:28359723 deoxynivalenol multiple interactions EXP 6480464 AKT1 protein affects the reaction [deoxynivalenol results in increased expression of IL6 mRNA] more ... CTD PMID:15976193 , PMID:16424113 deoxynivalenol increases phosphorylation EXP 6480464 deoxynivalenol results in increased phosphorylation of AKT1 protein CTD PMID:16424113 , PMID:24937323 desferrioxamine B multiple interactions ISO RGD:2081 6480464 Deferoxamine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:18032466 dexamethasone decreases phosphorylation ISO RGD:732909 6480464 Dexamethasone results in decreased phosphorylation of AKT1 protein CTD PMID:15576458 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of AKT1 mRNA CTD PMID:30878453 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of AKT1 protein CTD PMID:28292967 dexamethasone decreases phosphorylation ISO RGD:2081 6480464 Dexamethasone results in decreased phosphorylation of AKT1 protein CTD PMID:15187100 more ... dexamethasone decreases phosphorylation EXP 6480464 Dexamethasone results in decreased phosphorylation of AKT1 protein CTD PMID:22733784 more ... dexamethasone multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Dexamethasone results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:22733784 more ... dexamethasone multiple interactions ISO RGD:2081 6480464 [Dexamethasone co-treated with beta-hydroxyisovaleric acid] results in increased phosphorylation of AKT1 protein more ... CTD PMID:15187100 more ... diallyl disulfide increases phosphorylation ISO RGD:732909 6480464 diallyl disulfide results in increased phosphorylation of AKT1 protein CTD PMID:23663050 diallyl trisulfide multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]], diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] CTD PMID:23453443 diallyl trisulfide decreases phosphorylation ISO RGD:732909 6480464 diallyl trisulfide results in decreased phosphorylation of AKT1 protein CTD PMID:22020565 more ... diallyl trisulfide multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein] more ... CTD PMID:22020565 , PMID:24489685 diallyl trisulfide increases phosphorylation ISO RGD:732909 6480464 diallyl trisulfide results in increased phosphorylation of AKT1 protein CTD PMID:23663050 , PMID:24489685 diallyl trisulfide decreases expression ISO RGD:732909 6480464 diallyl trisulfide results in decreased expression of AKT1 mRNA, diallyl trisulfide results in decreased expression of AKT1 protein CTD PMID:19823037 , PMID:24415872 diarsenic trioxide affects stability ISO RGD:732909 6480464 Arsenic Trioxide affects the stability of AKT1 protein CTD PMID:18566239 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of AKT1 mRNA CTD PMID:30032600 , PMID:30225639 diarsenic trioxide multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:12168106 more ... diarsenic trioxide increases phosphorylation ISO RGD:732909 6480464 Arsenic Trioxide results in increased phosphorylation of AKT1 protein CTD PMID:25791921 , PMID:29266867 diarsenic trioxide multiple interactions EXP 6480464 Arsenic Trioxide inhibits the reaction [AKT1 protein binds to PPARG protein] more ... CTD PMID:15916724 more ... diarsenic trioxide decreases expression ISO RGD:732909 6480464 Arsenic Trioxide results in decreased expression of AKT1 mRNA, Arsenic Trioxide results in decreased expression of AKT1 protein CTD PMID:20458559 , PMID:30093655 diarsenic trioxide decreases phosphorylation EXP 6480464 Arsenic Trioxide results in decreased phosphorylation of AKT1 protein CTD PMID:20299303 , PMID:30362509 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of AKT1 protein CTD PMID:15688020 , PMID:21078540 diarsenic trioxide decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Arsenic Trioxide, AKT1 results in decreased susceptibility to Arsenic Trioxide CTD PMID:16115127 more ... diarsenic trioxide increases activity ISO RGD:732909 6480464 Arsenic Trioxide results in increased activity of AKT1 protein CTD PMID:19457607 diarsenic trioxide decreases phosphorylation ISO RGD:732909 6480464 Arsenic Trioxide results in decreased phosphorylation of AKT1 protein CTD PMID:16434995 more ... diazinon multiple interactions EXP 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein, [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 diazinon affects expression ISO RGD:2081 6480464 Diazinon affects the expression of AKT1 mRNA CTD PMID:22546817 diazoxide multiple interactions ISO RGD:2081 6480464 5-hydroxydecanoic acid inhibits the reaction [Diazoxide results in increased phosphorylation of AKT1 protein] CTD PMID:21256120 diazoxide increases phosphorylation ISO RGD:2081 6480464 Diazoxide results in increased phosphorylation of AKT1 protein CTD PMID:21256120 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [Endosulfan results in increased phosphorylation of AKT1 protein] CTD PMID:25199686 dibenziodolium multiple interactions ISO RGD:732909 6480464 diphenyleneiodonium inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein] CTD PMID:26514923 dibenzoylmethane multiple interactions EXP 6480464 [dibenzoylmethane co-treated with sulforafan] results in decreased phosphorylation of AKT1 protein CTD PMID:17942926 dibenzoylmethane decreases phosphorylation EXP 6480464 dibenzoylmethane results in decreased phosphorylation of AKT1 protein CTD PMID:17942926 dibutyl phthalate multiple interactions ISO RGD:732909 6480464 HDAC6 mutant form inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of AKT1 protein] CTD PMID:22552774 dibutyl phthalate increases phosphorylation ISO RGD:732909 6480464 Dibutyl Phthalate results in increased phosphorylation of AKT1 protein CTD PMID:22552774 dibutylstannane multiple interactions EXP 6480464 AKT1 protein affects the reaction [di-n-butyltin results in increased expression of IL6 mRNA], AKT1 protein affects the reaction [di-n-butyltin results in increased expression of IL6 protein] CTD PMID:24631921 dichlorine multiple interactions ISO RGD:2081 6480464 [Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA CTD PMID:18636392 diclofenac affects expression ISO RGD:732909 6480464 Diclofenac affects the expression of AKT1 mRNA CTD PMID:24752500 Dicyclohexyl phthalate decreases phosphorylation ISO RGD:2081 6480464 dicyclohexyl phthalate results in decreased phosphorylation of AKT1 protein CTD PMID:30391266 diethylstilbestrol increases phosphorylation EXP 6480464 Diethylstilbestrol results in increased phosphorylation of AKT1 protein CTD PMID:15171707 dihydro-beta-erythroidine multiple interactions ISO RGD:732909 6480464 Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:12511591 dihydrolipoamide multiple interactions ISO RGD:2081 6480464 dihydrolipoamide inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein] CTD PMID:15613977 dihydrolipoic acid multiple interactions ISO RGD:2081 6480464 dihydrolipoic acid inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:21251946 dimethylarsinic acid multiple interactions ISO RGD:732909 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of AKT1 mRNA CTD PMID:23192986 dioscin multiple interactions ISO RGD:732909 6480464 dioscin inhibits the reaction [VEGFA protein results in increased phosphorylation of AKT1 protein] CTD PMID:25111127 dioscin decreases expression ISO RGD:732909 6480464 dioscin results in decreased expression of AKT1 mRNA CTD PMID:29990575 diosgenin multiple interactions ISO RGD:732909 6480464 Diosgenin inhibits the reaction [TNF protein results in increased activity of AKT1 protein] CTD PMID:16331273 dioxygen multiple interactions ISO RGD:732909 6480464 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3 more ... CTD PMID:18924134 more ... dioxygen affects phosphorylation EXP 6480464 Oxygen deficiency affects the phosphorylation of AKT1 protein CTD PMID:25448280 dioxygen increases expression ISO RGD:732909 6480464 Oxygen deficiency results in increased expression of AKT1 mRNA CTD PMID:23452621 dioxygen increases phosphorylation ISO RGD:732909 6480464 Oxygen deficiency results in increased phosphorylation of AKT1 protein, Oxygen results in increased phosphorylation of AKT1 protein CTD PMID:19587783 more ... dioxygen increases phosphorylation ISO RGD:2081 6480464 Oxygen deficiency results in increased phosphorylation of AKT1 protein CTD PMID:24658657 , PMID:26476374 dioxygen increases expression ISO RGD:2081 6480464 Oxygen deficiency results in increased expression of AKT1 mRNA CTD PMID:26476374 dioxygen multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:19011674 more ... diquat multiple interactions EXP 6480464 PROP1 protein affects the reaction [Diquat results in increased phosphorylation of AKT1 protein] CTD PMID:20826540 diquat increases phosphorylation EXP 6480464 Diquat results in increased phosphorylation of AKT1 protein CTD PMID:20826540 disodium cromoglycate multiple interactions ISO RGD:2081 6480464 [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of AKT1 protein] CTD PMID:28732690 disodium selenite decreases expression ISO RGD:732909 6480464 Sodium Selenite results in decreased expression of AKT1 mRNA CTD PMID:16705456 disodium selenite multiple interactions EXP 6480464 Sodium Selenite inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein] CTD PMID:31419397 disodium selenite increases phosphorylation EXP 6480464 Sodium Selenite results in increased phosphorylation of AKT1 protein CTD PMID:31419397 disodium selenite multiple interactions ISO RGD:2081 6480464 mitoquinone inhibits the reaction [Sodium Selenite inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:21705299 more ... disodium selenite increases phosphorylation ISO RGD:732909 6480464 Sodium Selenite results in increased phosphorylation of AKT1 protein CTD PMID:12896980 , PMID:15845651 dithionite(2-) multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:21803128 divinyl sulfone decreases phosphorylation ISO RGD:732909 6480464 divinyl sulfone analog results in decreased phosphorylation of AKT1 protein CTD PMID:24875536 divinyl sulfone multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [divinyl sulfone analog results in decreased phosphorylation of AKT1 protein] CTD PMID:24875536 dobutamine affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to Dobutamine CTD PMID:16094411 dobutamine multiple interactions ISO RGD:2081 6480464 Dobutamine inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] CTD PMID:16339297 dorsomorphin multiple interactions ISO RGD:732909 6480464 dorsomorphin inhibits the reaction [rubimaillin results in decreased phosphorylation of AKT1 protein] CTD PMID:23466342 dorsomorphin multiple interactions EXP 6480464 [dorsomorphin co-treated with Quercetin] inhibits the reaction [[TNF protein co-treated with INS1 protein] results in decreased expression of AKT1 protein] CTD PMID:23439570 dorsomorphin increases phosphorylation ISO RGD:732909 6480464 dorsomorphin results in increased phosphorylation of AKT1 protein CTD PMID:23466342 doxazosin affects phosphorylation ISO RGD:2081 6480464 Doxazosin affects the phosphorylation of AKT1 protein CTD PMID:18084315 doxorubicin multiple interactions ISO RGD:732909 6480464 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3 more ... CTD PMID:16168102 more ... doxorubicin decreases phosphorylation ISO RGD:2081 6480464 Doxorubicin results in decreased phosphorylation of AKT1 protein CTD PMID:18379782 , PMID:27087047 doxorubicin decreases phosphorylation EXP 6480464 Doxorubicin results in decreased phosphorylation of AKT1 protein CTD PMID:18037988 more ... doxorubicin increases phosphorylation ISO RGD:2081 6480464 Doxorubicin results in increased phosphorylation of AKT1 protein CTD PMID:15613977 more ... doxorubicin increases phosphorylation ISO RGD:732909 6480464 Doxorubicin results in increased phosphorylation of AKT1 protein CTD PMID:17339365 , PMID:20826841 doxorubicin decreases phosphorylation ISO RGD:732909 6480464 Doxorubicin results in decreased phosphorylation of AKT1 protein CTD PMID:15494689 more ... doxorubicin multiple interactions ISO RGD:2081 6480464 AKT1 protein inhibits the reaction [Doxorubicin results in increased expression of FBXO32 mRNA] more ... CTD PMID:15613977 more ... doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of AKT1 protein CTD PMID:17531194 doxorubicin multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:15833803 more ... doxorubicin decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Doxorubicin CTD PMID:16782806 doxorubicin decreases expression ISO RGD:732909 6480464 Doxorubicin results in decreased expression of AKT1 mRNA, Doxorubicin results in decreased expression of AKT1 protein modified form CTD PMID:16438844 , PMID:29803840 eckol multiple interactions ISO RGD:732909 6480464 eckol results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:21514314 edaravone multiple interactions ISO RGD:2081 6480464 Edaravone inhibits the reaction [[IL1B protein results in increased phosphorylation of AKT1 protein] which results in increased expression of IL1R1 mRNA], Edaravone inhibits the reaction [[IL1B protein results in increased phosphorylation of AKT1 protein] which results in increased expression of IL1R1 protein] CTD PMID:18078833 elemental selenium multiple interactions ISO RGD:732909 6480464 [Selenium results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin more ... CTD PMID:17339365 elemental selenium increases phosphorylation ISO RGD:2081 6480464 Selenium results in increased phosphorylation of AKT1 protein CTD PMID:29324385 elemental selenium multiple interactions ISO RGD:2081 6480464 Selenium inhibits the reaction [arsenite results in decreased expression of and results in decreased phosphorylation of AKT1 protein] CTD PMID:29324385 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein] CTD PMID:17997286 elemental selenium increases expression ISO RGD:732909 6480464 Selenium results in increased expression of AKT1 mRNA CTD PMID:19244175 elemental selenium decreases phosphorylation ISO RGD:732909 6480464 Selenium results in decreased phosphorylation of AKT1 protein CTD PMID:17339365 ellagic acid increases phosphorylation ISO RGD:732909 6480464 Ellagic Acid results in increased phosphorylation of AKT1 protein CTD PMID:26986492 embelin decreases phosphorylation EXP 6480464 embelin results in decreased phosphorylation of AKT1 protein CTD PMID:24694877 embelin decreases phosphorylation ISO RGD:732909 6480464 embelin results in decreased phosphorylation of AKT1 protein CTD PMID:24694877 emodin multiple interactions ISO RGD:732909 6480464 [arsenic trioxide co-treated with IFNA2 protein co-treated with Docosahexaenoic Acids co-treated with Emodin] results in decreased expression of AKT1 protein more ... CTD PMID:17077332 more ... emodin decreases phosphorylation ISO RGD:732909 6480464 Emodin results in decreased phosphorylation of AKT1 protein CTD PMID:27032576 emodin multiple interactions ISO RGD:2081 6480464 Emodin inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:15288473 emodin decreases expression ISO RGD:732909 6480464 Emodin results in decreased expression of AKT1 mRNA CTD PMID:16045814 enalapril multiple interactions ISO RGD:2081 6480464 Enalapril promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein] CTD PMID:18806606 endosulfan increases phosphorylation EXP 6480464 Endosulfan results in increased phosphorylation of AKT1 protein CTD PMID:25199686 endosulfan multiple interactions EXP 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein more ... CTD PMID:19883720 , PMID:25199686 equol increases phosphorylation ISO RGD:732909 6480464 Equol results in increased phosphorylation of AKT1 protein CTD PMID:16840783 erlotinib hydrochloride decreases phosphorylation EXP 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of AKT1 protein CTD PMID:21195724 erlotinib hydrochloride multiple interactions ISO RGD:732909 6480464 Erlotinib Hydrochloride inhibits the reaction [Derp2 allergen, Dermatophagoides pteronyssinus results in increased phosphorylation of AKT1 protein] CTD PMID:30623574 esculetin increases phosphorylation ISO RGD:732909 6480464 esculetin results in increased phosphorylation of AKT1 protein CTD PMID:24995577 estrone increases phosphorylation ISO RGD:732909 6480464 Estrone results in increased phosphorylation of AKT1 protein CTD PMID:21767602 estrone multiple interactions ISO RGD:732909 6480464 wortmannin inhibits the reaction [Estrone results in increased phosphorylation of AKT1 protein] CTD PMID:21767602 ethanol multiple interactions EXP 6480464 [NR1H4 gene mutant form results in increased susceptibility to Ethanol] which results in increased phosphorylation of AKT1 protein more ... CTD PMID:24892905 more ... ethanol decreases phosphorylation ISO RGD:2081 6480464 Ethanol results in decreased phosphorylation of AKT1 protein CTD PMID:17685400 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of AKT1 mRNA CTD PMID:29524503 ethanol affects expression ISO RGD:2081 6480464 Ethanol affects the expression of AKT1 mRNA CTD PMID:31039417 ethanol decreases expression ISO RGD:732909 6480464 Ethanol results in decreased expression of AKT1 mRNA CTD PMID:31226463 ethanol decreases expression ISO RGD:2081 6480464 Ethanol results in decreased expression of AKT1 mRNA CTD PMID:31226463 ethanol decreases phosphorylation EXP 6480464 Ethanol results in decreased phosphorylation of AKT1 protein CTD PMID:24095927 more ... ethanol increases phosphorylation ISO RGD:732909 6480464 Ethanol results in increased phosphorylation of AKT1 protein CTD PMID:26220687 ethanol increases phosphorylation EXP 6480464 Ethanol results in increased phosphorylation of AKT1 protein CTD PMID:22459179 , PMID:28962519 ethanol multiple interactions ISO RGD:2081 6480464 [Ethanol results in decreased susceptibility to INS1 protein] which results in increased activity of AKT1 protein more ... CTD PMID:12700235 , PMID:17347304 ethanol multiple interactions ISO RGD:732909 6480464 [[Gasoline co-treated with Ethanol] results in increased chemical synthesis of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of AKT1 mRNA more ... CTD PMID:18295389 more ... ethyl trans-caffeate multiple interactions ISO RGD:732909 6480464 ethyl caffeate affects the phosphorylation of and affects the activity of AKT1 protein CTD PMID:24892518 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:2081 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:21544200 etoposide increases response to substance ISO RGD:732909 6480464 AKT1 protein modified form results in increased susceptibility to Etoposide CTD PMID:17699715 etoposide increases phosphorylation ISO RGD:732909 6480464 Etoposide results in increased phosphorylation of AKT1 protein CTD PMID:27769712 etoposide multiple interactions ISO RGD:732909 6480464 Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein more ... CTD PMID:17699715 , PMID:17935137 everolimus decreases phosphorylation ISO RGD:732909 6480464 Everolimus results in decreased phosphorylation of AKT1 protein CTD PMID:22885370 everolimus increases phosphorylation ISO RGD:732909 6480464 Everolimus results in increased phosphorylation of AKT1 protein CTD PMID:16033851 more ... Evodiamine decreases phosphorylation ISO RGD:732909 6480464 evodiamine results in decreased phosphorylation of AKT1 protein CTD PMID:20005289 Evodiamine multiple interactions ISO RGD:732909 6480464 evodiamine inhibits the reaction [TNF protein results in increased activity of AKT1 protein], wortmannin promotes the reaction [evodiamine results in decreased phosphorylation of AKT1 protein] CTD PMID:15710601 , PMID:20005289 Evodiamine multiple interactions EXP 6480464 evodiamine inhibits the reaction [INS1 results in increased phosphorylation of AKT1 protein] CTD PMID:17884939 excitatory amino acid agonist decreases phosphorylation ISO RGD:2081 6480464 Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein CTD PMID:19201465 excitatory amino acid agonist multiple interactions ISO RGD:2081 6480464 mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein], morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein] CTD PMID:19201465 fasudil hydrochloride multiple interactions ISO RGD:2081 6480464 fasudil results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17761835 ferric oxide multiple interactions ISO RGD:2081 6480464 [ferric oxide analog co-treated with Acrolein] results in increased phosphorylation of AKT1 protein CTD PMID:24847785 filipin III multiple interactions ISO RGD:732909 6480464 Filipin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 filipin III multiple interactions ISO RGD:2081 6480464 Filipin inhibits the reaction [ferrous sulfate results in increased phosphorylation of AKT1 protein], Filipin inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein] CTD PMID:17172471 fingolimod hydrochloride multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:25939952 fingolimod hydrochloride decreases phosphorylation ISO RGD:732909 6480464 Fingolimod Hydrochloride results in decreased phosphorylation of AKT1 protein CTD PMID:25939952 fisetin increases phosphorylation ISO RGD:2081 6480464 fisetin results in increased phosphorylation of AKT1 protein CTD PMID:25428606 fisetin multiple interactions ISO RGD:732909 6480464 fisetin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein] CTD PMID:20153296 flurbiprofen multiple interactions EXP 6480464 [Flurbiprofen results in increased phosphorylation of and results in increased activity of PSCA protein] which results in increased expression of AKT1 protein more ... CTD PMID:16949054 flutamide increases activity ISO RGD:2081 6480464 Flutamide results in increased activity of AKT1 protein CTD PMID:20850791 flutamide increases expression ISO RGD:2081 6480464 Flutamide results in increased expression of AKT1 protein CTD PMID:26437446 flutamide multiple interactions ISO RGD:732909 6480464 Flutamide inhibits the reaction [Testosterone inhibits the reaction [Phosphates results in decreased phosphorylation of AKT1 protein]] CTD PMID:20048160 formaldehyde multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[HSPA1A protein co-treated with Formaldehyde] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:30600586 frenolicin B multiple interactions ISO RGD:732909 6480464 frenolicin B binds to and results in decreased activity of AKT1 protein CTD PMID:19309081 fructose decreases phosphorylation ISO RGD:2081 6480464 Fructose results in decreased phosphorylation of AKT1 protein CTD PMID:18497449 more ... fructose increases phosphorylation ISO RGD:2081 6480464 Fructose results in increased phosphorylation of AKT1 protein CTD PMID:23533474 fructose multiple interactions ISO RGD:2081 6480464 [Fructose co-treated with Oleanolic Acid] results in increased expression of AKT1 mRNA more ... CTD PMID:19008412 more ... fucoxanthin multiple interactions EXP 6480464 fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein] CTD PMID:26418808 fulvestrant multiple interactions ISO RGD:732909 6480464 [Fulvestrant co-treated with 4-(6-bromo-1 more ... CTD PMID:16168102 more ... fulvestrant increases phosphorylation ISO RGD:2081 6480464 fulvestrant results in increased phosphorylation of AKT1 protein CTD PMID:16951259 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein] CTD PMID:25461906 fulvestrant multiple interactions ISO RGD:2081 6480464 [Estradiol co-treated with fulvestrant] results in increased phosphorylation of AKT1 protein, fulvestrant inhibits the reaction [Promegestone results in increased phosphorylation of AKT1 protein] CTD PMID:16020483 , PMID:16951259 furazolidone multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Furazolidone results in decreased phosphorylation of AKT1 protein], IGF1 protein inhibits the reaction [Furazolidone results in decreased phosphorylation of AKT1 protein] CTD PMID:26687534 furazolidone decreases phosphorylation ISO RGD:732909 6480464 Furazolidone results in decreased phosphorylation of AKT1 protein CTD PMID:26687534 furosemide affects phosphorylation ISO RGD:2081 6480464 Furosemide affects the phosphorylation of AKT1 protein CTD PMID:17497460 gadodiamide hydrate multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein] CTD PMID:19561517 gadodiamide hydrate increases phosphorylation ISO RGD:732909 6480464 gadodiamide results in increased phosphorylation of AKT1 protein CTD PMID:19561517 galangin decreases phosphorylation ISO RGD:732909 6480464 galangin results in decreased phosphorylation of AKT1 protein CTD PMID:18455702 gallic acid decreases activity ISO RGD:732909 6480464 Gallic Acid results in decreased activity of AKT1 protein CTD PMID:22387266 gallic acid decreases phosphorylation ISO RGD:732909 6480464 Gallic Acid results in decreased phosphorylation of AKT1 protein CTD PMID:23153558 , PMID:26530725 gallic acid multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:23153558 more ... gallocatechin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:29061316 gamma-aminobutyric acid increases phosphorylation ISO RGD:2081 6480464 gamma-Aminobutyric Acid results in increased phosphorylation of AKT1 protein CTD PMID:29708300 gamma-hexachlorocyclohexane decreases phosphorylation ISO RGD:2081 6480464 Hexachlorocyclohexane results in decreased phosphorylation of AKT1 protein CTD PMID:30248393 gamma-mangostin decreases phosphorylation ISO RGD:732909 6480464 gamma-mangostin results in decreased phosphorylation of AKT1 protein CTD PMID:30502394 gamma-mangostin multiple interactions ISO RGD:732909 6480464 [gamma-mangostin co-treated with MK 2206] results in decreased phosphorylation of AKT1 protein CTD PMID:30502394 Garcinol multiple interactions ISO RGD:732909 6480464 garcinol results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:16052481 gefitinib multiple interactions ISO RGD:732909 6480464 Gefitinib affects the reaction [ON123300 results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:17805209 more ... gefitinib multiple interactions EXP 6480464 gefitinib inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein] CTD PMID:23948867 geldanamycin multiple interactions ISO RGD:732909 6480464 [geldanamycin co-treated with Bortezomib] results in decreased expression of AKT1 protein more ... CTD PMID:15781649 more ... geldanamycin decreases expression ISO RGD:732909 6480464 geldanamycin results in decreased expression of AKT1 protein CTD PMID:24211270 geldanamycin decreases phosphorylation ISO RGD:732909 6480464 geldanamycin results in decreased phosphorylation of AKT1 protein CTD PMID:17293044 , PMID:24450340 gemcitabine affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to gemcitabine CTD PMID:15867245 gemcitabine multiple interactions ISO RGD:732909 6480464 [gemcitabine co-treated with licoricidin] results in decreased phosphorylation of AKT1 protein, [licoricidin co-treated with gemcitabine] results in decreased phosphorylation of AKT1 protein CTD PMID:29782821 gemfibrozil increases phosphorylation EXP 6480464 Gemfibrozil results in increased phosphorylation of AKT1 protein CTD PMID:22685291 gemfibrozil affects localization EXP 6480464 Gemfibrozil affects the localization of AKT1 protein CTD PMID:22685291 Genipin multiple interactions ISO RGD:732909 6480464 genipin inhibits the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein] CTD PMID:29630948 Geniposide multiple interactions ISO RGD:2081 6480464 geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein] CTD PMID:22819839 genistein affects binding ISO RGD:732909 6480464 Genistein binds to AKT1 protein CTD PMID:16789737 genistein multiple interactions ISO RGD:2081 6480464 bisphenol A inhibits the reaction [Genistein results in increased phosphorylation of AKT1 protein] more ... CTD PMID:20685402 more ... genistein increases phosphorylation ISO RGD:2081 6480464 Genistein results in increased phosphorylation of AKT1 protein CTD PMID:22504913 , PMID:24884420 genistein decreases expression ISO RGD:732909 6480464 Genistein results in decreased expression of AKT1 protein CTD PMID:24299158 genistein decreases phosphorylation ISO RGD:732909 6480464 Genistein results in decreased phosphorylation of AKT1 protein CTD PMID:15829497 more ... genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of AKT1 protein], Genistein inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein] CTD PMID:21078540 , PMID:30734460 genistein decreases phosphorylation EXP 6480464 Genistein results in decreased phosphorylation of AKT1 protein CTD PMID:21078540 genistein multiple interactions ISO RGD:732909 6480464 Genistein inhibits the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:19038232 more ... gentamycin decreases expression ISO RGD:2081 6480464 Gentamicins results in decreased expression of AKT1 mRNA CTD PMID:20623750 gentamycin increases expression ISO RGD:2081 6480464 Gentamicins results in increased expression of AKT1 mRNA CTD PMID:22061828 Geraniin multiple interactions EXP 6480464 Geraniin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of AKT1 protein] CTD PMID:27181634 GGTI-2133 multiple interactions ISO RGD:2081 6480464 GGTI-2133 inhibits the reaction [Smoke analog results in increased phosphorylation of AKT1 protein] CTD PMID:19299917 gingerol multiple interactions ISO RGD:732909 6480464 gingerol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein] CTD PMID:27451028 ginkgolide B multiple interactions ISO RGD:732909 6480464 ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19464278 ginsenoside Rb1 increases phosphorylation ISO RGD:732909 6480464 ginsenoside Rb1 results in increased phosphorylation of AKT1 protein CTD PMID:19781563 ginsenoside Rb1 multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rb1 results in increased phosphorylation of AKT1 protein] more ... CTD PMID:19781563 ginsenoside Rd multiple interactions EXP 6480464 ginsenoside Rd results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:24599032 ginsenoside Re multiple interactions EXP 6480464 ginsenoside Re results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:24599032 ginsenoside Re increases phosphorylation EXP 6480464 ginsenoside Re results in increased phosphorylation of AKT1 protein CTD PMID:17885204 ginsenoside Re increases phosphorylation ISO RGD:2081 6480464 ginsenoside Re results in increased phosphorylation of AKT1 protein CTD PMID:17878692 ginsenoside Rg2 multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein]], ginsenoside Rg2 inhibits the reaction [APP protein modified form results in decreased phosphorylation of AKT1 protein] CTD PMID:28756148 glucose multiple interactions EXP 6480464 [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein more ... CTD PMID:15806154 more ... glucose decreases phosphorylation ISO RGD:732909 6480464 Glucose results in decreased phosphorylation of AKT1 protein CTD PMID:21333731 more ... glucose increases phosphorylation ISO RGD:2081 6480464 Glucose results in increased phosphorylation of AKT1 protein CTD PMID:23159718 more ... glucose decreases phosphorylation ISO RGD:2081 6480464 Glucose results in decreased phosphorylation of AKT1 protein CTD PMID:23453443 more ... glucose increases phosphorylation ISO RGD:732909 6480464 Glucose results in increased phosphorylation of AKT1 protein CTD PMID:21333731 glucose increases response to substance EXP 6480464 AKT1 protein mutant form results in increased susceptibility to Glucose deficiency CTD PMID:15806154 glucose decreases expression ISO RGD:2081 6480464 Glucose results in decreased expression of AKT1 protein modified form CTD PMID:18004065 glucose multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:16385087 more ... glucose multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:18004065 more ... glutathione multiple interactions ISO RGD:732909 6480464 Glutathione inhibits the reaction [Curcumin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]], Glutathione inhibits the reaction [Pyocyanine results in increased phosphorylation of AKT1 protein] CTD PMID:17640567 , PMID:24015256 glyburide multiple interactions ISO RGD:2081 6480464 Glyburide inhibits the reaction [sodium bisulfide results in increased phosphorylation of AKT1 protein] CTD PMID:21800153 glycerol multiple interactions EXP 6480464 arsenic trioxide inhibits the reaction [Glycerol results in increased phosphorylation of AKT1 protein] CTD PMID:20299303 glycerol increases phosphorylation EXP 6480464 Glycerol results in increased phosphorylation of AKT1 protein CTD PMID:20299303 Goe 6976 decreases phosphorylation EXP 6480464 Go 6976 results in decreased phosphorylation of AKT1 protein CTD PMID:19393235 gold atom multiple interactions ISO RGD:732909 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of AKT1 protein CTD PMID:27470402 gold(0) multiple interactions ISO RGD:732909 6480464 [Quercetin analog co-treated with Gold analog] results in decreased phosphorylation of AKT1 protein CTD PMID:27470402 GSK690693 decreases phosphorylation ISO RGD:732909 6480464 GSK690693 results in decreased phosphorylation of AKT1 protein CTD PMID:31445927 GSK690693 multiple interactions ISO RGD:732909 6480464 GSK690693 promotes the reaction [1, 4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein] CTD PMID:30871965 haloperidol decreases expression ISO RGD:2081 6480464 Haloperidol results in decreased expression of AKT1 mRNA CTD PMID:15860345 hellebrigenin multiple interactions ISO RGD:732909 6480464 hellebrigenin results in decreased phosphorylation of and results in decreased expression of AKT1 protein CTD PMID:24954031 hemin multiple interactions ISO RGD:732909 6480464 Hemin inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] CTD PMID:18215737 heparin multiple interactions ISO RGD:2081 6480464 Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of AKT1 protein], Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:14966081 hesperetin multiple interactions ISO RGD:2081 6480464 hesperetin affects the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein] CTD PMID:19222219 hesperidin multiple interactions ISO RGD:2081 6480464 Hesperidin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein] CTD PMID:30779474 hexachlorobenzene multiple interactions ISO RGD:2081 6480464 AKT1 protein promotes the reaction [Hexachlorobenzene results in decreased expression of GJB1 mRNA] more ... CTD PMID:16679308 , PMID:17150971 hexadecanoic acid decreases phosphorylation ISO RGD:2081 6480464 Palmitic Acid results in decreased phosphorylation of AKT1 protein CTD PMID:22819839 hexadecanoic acid multiple interactions ISO RGD:732909 6480464 Palmitic Acid inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein], Palmitic Acid inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein] CTD PMID:22683933 , PMID:30362509 hexadecanoic acid multiple interactions ISO RGD:2081 6480464 geniposide inhibits the reaction [Palmitic Acid results in decreased phosphorylation of AKT1 protein], Palmitic Acid inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22713545 , PMID:22819839 high-density lipoprotein cholesterol multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Cholesterol, HDL results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in decreased degradation of NOS3 protein] more ... CTD PMID:12821261 homocysteine multiple interactions EXP 6480464 Atorvastatin inhibits the reaction [Homocysteine results in decreased phosphorylation of AKT1 protein] CTD PMID:20305681 homocysteine decreases phosphorylation EXP 6480464 Homocysteine results in decreased phosphorylation of AKT1 protein CTD PMID:20305681 hyaluronic acid multiple interactions ISO RGD:2081 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein] CTD PMID:23178681 hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of AKT1 protein CTD PMID:15123721 , PMID:27494022 hydrogen peroxide decreases phosphorylation ISO RGD:2081 6480464 Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein CTD PMID:16249675 more ... hydrogen peroxide multiple interactions ISO RGD:2081 6480464 1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:12472888 more ... hydrogen peroxide increases phosphorylation ISO RGD:732909 6480464 Hydrogen Peroxide results in increased phosphorylation of AKT1 protein CTD PMID:22020565 more ... hydrogen peroxide decreases phosphorylation ISO RGD:732909 6480464 Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein CTD PMID:19451193 more ... hydrogen peroxide affects expression ISO RGD:732909 6480464 Hydrogen Peroxide affects the expression of AKT1 protein CTD PMID:21179406 hydrogen peroxide increases phosphorylation ISO RGD:2081 6480464 Hydrogen Peroxide results in increased phosphorylation of AKT1 protein CTD PMID:12472888 more ... hydrogen peroxide affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to Hydrogen Peroxide CTD PMID:12361705 hydrogen peroxide multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Gallic Acid co-treated with gallocatechol co-treated with epigallocatechin gallate co-treated with epicatechin gallate] inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:17325745 more ... hydrogen peroxide affects phosphorylation ISO RGD:2081 6480464 Hydrogen Peroxide affects the phosphorylation of AKT1 protein CTD PMID:19222219 hydrogen peroxide multiple interactions EXP 6480464 [PI103 co-treated with Hydrogen Peroxide] results in decreased expression of AKT1 protein more ... CTD PMID:15123721 more ... hydroquinone multiple interactions EXP 6480464 hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17464197 hydroquinone O-beta-D-glucopyranoside decreases expression ISO RGD:732909 6480464 Arbutin results in decreased expression of AKT1 mRNA CTD PMID:17103032 hydroxyflutamide increases phosphorylation ISO RGD:2081 6480464 hydroxyflutamide results in increased phosphorylation of AKT1 protein CTD PMID:26437446 hydroxyflutamide multiple interactions ISO RGD:2081 6480464 hydroxyflutamide promotes the reaction [Testosterone results in increased phosphorylation of AKT1 protein], wortmannin inhibits the reaction [hydroxyflutamide results in increased phosphorylation of AKT1 protein] CTD PMID:26437446 IC-87114 decreases phosphorylation ISO RGD:732909 6480464 IC 87114 results in decreased phosphorylation of AKT1 protein CTD PMID:19176369 IC-87114 decreases phosphorylation EXP 6480464 IC 87114 results in decreased phosphorylation of AKT1 protein CTD PMID:16179367 IC-87114 multiple interactions EXP 6480464 IC 87114 inhibits the reaction [IL4 protein results in increased phosphorylation of AKT1 protein] CTD PMID:16179367 icariside II decreases phosphorylation ISO RGD:732909 6480464 baohuoside I results in decreased phosphorylation of AKT1 protein CTD PMID:25119583 icariside II multiple interactions ISO RGD:732909 6480464 baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein] CTD PMID:25119583 idelalisib multiple interactions ISO RGD:732909 6480464 2-amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester inhibits the reaction [[idelalisib co-treated with FASLG protein] results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:23676220 , PMID:31445927 idelalisib decreases phosphorylation EXP 6480464 idelalisib results in decreased phosphorylation of AKT1 protein CTD PMID:31445927 idelalisib decreases phosphorylation ISO RGD:732909 6480464 idelalisib results in decreased phosphorylation of AKT1 protein CTD PMID:23676220 , PMID:31445927 indometacin multiple interactions ISO RGD:732909 6480464 pyrazolanthrone inhibits the reaction [Indomethacin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17341418 , PMID:17654042 indometacin increases phosphorylation ISO RGD:732909 6480464 Indomethacin results in increased phosphorylation of AKT1 protein CTD PMID:17341418 indometacin decreases expression ISO RGD:732909 6480464 Indomethacin results in decreased expression of AKT1 protein modified form CTD PMID:17654042 ionomycin multiple interactions ISO RGD:732909 6480464 [Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein more ... CTD PMID:22317921 , PMID:28634229 irbesartan multiple interactions EXP 6480464 Cholesterol inhibits the reaction [irbesartan results in increased expression of AKT1 protein] CTD PMID:19028402 iron atom multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17172471 iron atom increases phosphorylation ISO RGD:2081 6480464 Iron results in increased phosphorylation of AKT1 protein CTD PMID:17172471 iron(0) multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17172471 iron(0) increases phosphorylation ISO RGD:2081 6480464 Iron results in increased phosphorylation of AKT1 protein CTD PMID:17172471 iron(2+) sulfate (anhydrous) multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ferrous sulfate results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17172471 iron(2+) sulfate (anhydrous) increases phosphorylation ISO RGD:2081 6480464 ferrous sulfate results in increased phosphorylation of AKT1 protein CTD PMID:17172471 isoflurane increases phosphorylation ISO RGD:2081 6480464 Isoflurane results in increased phosphorylation of AKT1 protein CTD PMID:16249675 isoflurane multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:25597859 isoflurane decreases phosphorylation ISO RGD:2081 6480464 Isoflurane results in decreased phosphorylation of AKT1 protein CTD PMID:25597859 isoliquiritigenin decreases phosphorylation ISO RGD:732909 6480464 isoliquiritigenin results in decreased phosphorylation of AKT1 protein CTD PMID:23747687 , PMID:25094029 isoliquiritigenin multiple interactions EXP 6480464 isoliquiritigenin inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:27117918 isoliquiritigenin multiple interactions ISO RGD:732909 6480464 20-hydroxyeicosa-5(Z) more ... CTD PMID:23747687 , PMID:25094029 isoliquiritigenin decreases response to substance ISO RGD:732909 6480464 AKT1 protein modified form results in decreased susceptibility to isoliquiritigenin CTD PMID:23747687 , PMID:25094029 isoorientin multiple interactions ISO RGD:732909 6480464 homoorientin promotes the reaction [Zinc Oxide analog results in decreased phosphorylation of AKT1 protein], Zinc Oxide analog promotes the reaction [homoorientin results in decreased phosphorylation of AKT1 protein] CTD PMID:24374571 isoorientin decreases phosphorylation ISO RGD:732909 6480464 homoorientin results in decreased phosphorylation of AKT1 protein CTD PMID:24374571 isoprenaline increases phosphorylation EXP 6480464 Isoproterenol results in increased phosphorylation of AKT1 protein CTD PMID:15618457 , PMID:31009642 isoprenaline increases phosphorylation ISO RGD:2081 6480464 Isoproterenol results in increased phosphorylation of AKT1 protein CTD PMID:15951400 more ... isoprenaline multiple interactions ISO RGD:2081 6480464 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one promotes the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein] more ... CTD PMID:15951400 more ... isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of AKT1 mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:15178407 , PMID:31009642 isorhamnetin decreases phosphorylation EXP 6480464 3-methylquercetin results in decreased phosphorylation of AKT1 protein CTD PMID:12826665 isorhamnetin multiple interactions ISO RGD:2081 6480464 3-methylquercetin affects the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein] CTD PMID:19222219 kaempferol multiple interactions ISO RGD:732909 6480464 kaempferol inhibits the reaction [HGF protein results in increased phosphorylation of AKT1 protein], kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] CTD PMID:19244381 , PMID:20438634 kaempferol decreases phosphorylation ISO RGD:732909 6480464 kaempferol results in decreased phosphorylation of AKT1 protein CTD PMID:20438634 kaempferol multiple interactions EXP 6480464 kaempferol inhibits the reaction [INS1 protein results in increased activity of AKT1 protein] CTD PMID:18591783 kahweol multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [kahweol results in decreased phosphorylation of AKT1 protein], kahweol promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein] CTD PMID:30205135 kahweol decreases phosphorylation ISO RGD:732909 6480464 kahweol results in decreased phosphorylation of AKT1 protein CTD PMID:30205135 ketanserin multiple interactions EXP 6480464 [[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein more ... CTD PMID:22975078 KN-93 multiple interactions ISO RGD:2081 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein] CTD PMID:19233221 , PMID:21933187 KN-93 multiple interactions ISO RGD:732909 6480464 KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of AKT1 protein] CTD PMID:28025122 kojic acid decreases expression ISO RGD:732909 6480464 kojic acid results in decreased expression of AKT1 mRNA CTD PMID:16595896 KT 5720 multiple interactions ISO RGD:2081 6480464 KT 5720 inhibits the reaction [Taurolithocholic Acid results in increased phosphorylation of AKT1 protein] CTD PMID:31300867 Ku-0063794 decreases phosphorylation ISO RGD:732909 6480464 Ku 0063794 results in decreased phosphorylation of AKT1 protein CTD PMID:22885370 L-1,4-dithiothreitol multiple interactions ISO RGD:732909 6480464 Dithiothreitol inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 L-ascorbic acid multiple interactions ISO RGD:2081 6480464 [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein], Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein] CTD PMID:21262251 , PMID:21911000 L-cysteine multiple interactions ISO RGD:2081 6480464 Cysteine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:15158331 L-methionine multiple interactions ISO RGD:2081 6480464 Methionine inhibits the reaction [PDGFB protein results in increased phosphorylation of AKT1 protein] CTD PMID:15158331 lapatinib multiple interactions ISO RGD:732909 6480464 [Bortezomib co-treated with lapatinib] results in decreased phosphorylation of AKT1 protein CTD PMID:20701607 lapatinib decreases phosphorylation ISO RGD:732909 6480464 Lapatinib results in decreased phosphorylation of AKT1 protein CTD PMID:19509167 , PMID:29387217 lapatinib decreases activity ISO RGD:732909 6480464 lapatinib results in decreased activity of AKT1 protein CTD PMID:15665275 lapatinib decreases expression ISO RGD:732909 6480464 lapatinib results in decreased expression of AKT1 protein, lapatinib results in decreased expression of AKT1 protein modified form CTD PMID:16091755 , PMID:19435893 lead diacetate increases phosphorylation EXP 6480464 lead acetate results in increased phosphorylation of AKT1 protein CTD PMID:24530660 lead diacetate increases phosphorylation ISO RGD:732909 6480464 lead acetate results in increased phosphorylation of AKT1 protein CTD PMID:26542248 lead diacetate multiple interactions ISO RGD:2081 6480464 Genistein inhibits the reaction [lead acetate results in increased phosphorylation of AKT1 protein] CTD PMID:26797587 lead diacetate increases phosphorylation ISO RGD:2081 6480464 lead acetate results in increased phosphorylation of AKT1 protein CTD PMID:26797587 lead(0) increases phosphorylation ISO RGD:2081 6480464 Lead results in increased phosphorylation of AKT1 protein CTD PMID:22129743 lead(0) multiple interactions ISO RGD:2081 6480464 Plant Extracts inhibits the reaction [Lead results in increased phosphorylation of AKT1 protein] CTD PMID:22129743 lead(2+) increases phosphorylation ISO RGD:2081 6480464 Lead results in increased phosphorylation of AKT1 protein CTD PMID:22129743 lead(2+) multiple interactions ISO RGD:2081 6480464 Plant Extracts inhibits the reaction [Lead results in increased phosphorylation of AKT1 protein] CTD PMID:22129743 leptomycin B increases phosphorylation ISO RGD:732909 6480464 leptomycin B results in increased phosphorylation of AKT1 protein CTD PMID:28942004 leptomycin B multiple interactions ISO RGD:732909 6480464 leptomycin B inhibits the reaction [gefitinib results in decreased phosphorylation of AKT1 protein] CTD PMID:28942004 leukotriene B4 multiple interactions ISO RGD:732909 6480464 Leukotriene B4 inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein] CTD PMID:23747687 leupeptin multiple interactions ISO RGD:732909 6480464 leupeptin inhibits the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein] CTD PMID:21818627 leuprolide multiple interactions ISO RGD:732909 6480464 Leuprolide inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:17143537 licoricidin decreases phosphorylation ISO RGD:732909 6480464 licoricidin results in decreased phosphorylation of AKT1 protein CTD PMID:29782821 licoricidin multiple interactions ISO RGD:732909 6480464 [gemcitabine co-treated with licoricidin] results in decreased phosphorylation of AKT1 protein, [licoricidin co-treated with gemcitabine] results in decreased phosphorylation of AKT1 protein CTD PMID:29782821 linalool increases expression ISO RGD:732909 6480464 linalool results in increased expression of AKT1 mRNA CTD PMID:19922762 linsidomine increases metabolic processing EXP 6480464 linsidomine results in increased metabolism of AKT1 protein CTD PMID:19682478 linsidomine increases phosphorylation ISO RGD:2081 6480464 linsidomine results in increased phosphorylation of AKT1 protein CTD PMID:17302912 linsidomine multiple interactions ISO RGD:2081 6480464 wortmannin inhibits the reaction [linsidomine results in increased phosphorylation of AKT1 protein] CTD PMID:17302912 linsidomine multiple interactions EXP 6480464 linsidomine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:19682478 lipoic acid decreases phosphorylation EXP 6480464 Thioctic Acid results in decreased phosphorylation of AKT1 protein CTD PMID:21351249 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in decreased expression of AKT1 mRNA] CTD PMID:27260466 lipopolysaccharide multiple interactions ISO RGD:2081 6480464 Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein more ... CTD PMID:18047562 more ... lipopolysaccharide decreases phosphorylation ISO RGD:732909 6480464 Lipopolysaccharides results in decreased phosphorylation of AKT1 protein CTD PMID:28245985 lipopolysaccharide decreases phosphorylation ISO RGD:2081 6480464 Lipopolysaccharides results in decreased phosphorylation of AKT1 protein CTD PMID:18047562 lipopolysaccharide increases phosphorylation ISO RGD:2081 6480464 Lipopolysaccharides results in increased phosphorylation of AKT1 protein CTD PMID:17172471 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of AKT1 mRNA CTD PMID:21212295 , PMID:25843059 lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of AKT1 protein CTD PMID:16724238 more ... lipopolysaccharide increases activity EXP 6480464 Lipopolysaccharides results in increased activity of AKT1 protein CTD PMID:17322126 lipopolysaccharide multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:16724238 more ... lipopolysaccharide increases phosphorylation ISO RGD:732909 6480464 Lipopolysaccharides results in increased phosphorylation of AKT1 protein CTD PMID:21078380 more ... lipopolysaccharide multiple interactions ISO RGD:732909 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:22003094 more ... lipoteichoic acid increases phosphorylation ISO RGD:2081 6480464 lipoteichoic acid results in increased phosphorylation of AKT1 protein CTD PMID:20685402 lipoteichoic acid multiple interactions ISO RGD:2081 6480464 Genistein inhibits the reaction [lipoteichoic acid results in increased phosphorylation of AKT1 protein] more ... CTD PMID:20685402 lipoteichoic acid increases phosphorylation EXP 6480464 lipoteichoic acid results in increased phosphorylation of AKT1 protein CTD PMID:23500011 liraglutide multiple interactions ISO RGD:732909 6480464 Liraglutide inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein], Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of AKT1 protein]] CTD PMID:31173752 lithium atom increases expression ISO RGD:732909 6480464 Lithium results in increased expression of AKT1 mRNA, Lithium results in increased expression of AKT1 protein CTD PMID:19440698 lithium atom increases phosphorylation ISO RGD:732909 6480464 Lithium results in increased phosphorylation of AKT1 protein CTD PMID:19440698 lithium chloride multiple interactions ISO RGD:732909 6480464 Lithium Chloride inhibits the reaction [baicalein results in decreased phosphorylation of AKT1 protein] CTD PMID:22820424 lithium chloride multiple interactions ISO RGD:2081 6480464 [Lithium Chloride co-treated with Pilocarpine] results in increased phosphorylation of AKT1 protein CTD PMID:31018114 lithium hydride increases phosphorylation ISO RGD:732909 6480464 Lithium results in increased phosphorylation of AKT1 protein CTD PMID:19440698 lithium hydride increases expression ISO RGD:732909 6480464 Lithium results in increased expression of AKT1 mRNA, Lithium results in increased expression of AKT1 protein CTD PMID:19440698 LM-1685 multiple interactions ISO RGD:732909 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[LM-1685 co-treated with carboxyamido-triazole] results in decreased expression of AKT1 protein modified form] CTD PMID:15867384 lonafarnib multiple interactions ISO RGD:732909 6480464 [Bortezomib co-treated with lonafarnib] results in decreased expression of AKT1 protein, [Bortezomib co-treated with lonafarnib] results in decreased expression of AKT1 protein modified form CTD PMID:16118318 lonidamine multiple interactions ISO RGD:732909 6480464 arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of AKT1 protein], lonidamine promotes the reaction [Curcumin results in decreased phosphorylation of AKT1 protein] CTD PMID:20605902 , PMID:21889928 lonidamine increases phosphorylation ISO RGD:732909 6480464 lonidamine results in increased phosphorylation of AKT1 protein CTD PMID:21889928 lovastatin multiple interactions ISO RGD:732909 6480464 Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein] CTD PMID:19760159 lovastatin decreases phosphorylation ISO RGD:2081 6480464 Lovastatin results in decreased phosphorylation of AKT1 protein CTD PMID:20578043 lovastatin decreases phosphorylation ISO RGD:732909 6480464 Lovastatin results in decreased phosphorylation of AKT1 protein CTD PMID:16425225 , PMID:17472962 luteolin multiple interactions ISO RGD:732909 6480464 Luteolin inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of AKT1 protein] more ... CTD PMID:20153296 more ... luteolin decreases phosphorylation ISO RGD:732909 6480464 Luteolin results in decreased phosphorylation of AKT1 protein CTD PMID:19344998 luteolin multiple interactions EXP 6480464 Luteolin inhibits the reaction [Antimycin A results in decreased activity of AKT1 protein] more ... CTD PMID:18591783 more ... luteolin multiple interactions ISO RGD:2081 6480464 [Luteolin co-treated with Hydrogen Peroxide] results in increased expression of AKT1 protein, Luteolin inhibits the reaction [lipoteichoic acid results in increased phosphorylation of AKT1 protein] CTD PMID:20685402 , PMID:27525270 luteolin increases phosphorylation ISO RGD:732909 6480464 Luteolin results in increased phosphorylation of AKT1 protein CTD PMID:27474067 luteolin decreases expression ISO RGD:732909 6480464 Luteolin results in decreased expression of AKT1 protein CTD PMID:22926442 LY 117018 decreases phosphorylation ISO RGD:732909 6480464 LY 117018 results in decreased phosphorylation of AKT1 protein CTD PMID:15876410 LY294002 multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the localization of [PDK1 protein binds to AKT1 protein] more ... CTD PMID:11788791 more ... LY294002 decreases expression ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of AKT1 mRNA CTD PMID:27338800 LY294002 decreases phosphorylation ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein CTD PMID:12640124 more ... LY294002 decreases phosphorylation ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein CTD PMID:17922026 LY294002 decreases expression EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of AKT1 protein CTD PMID:15695173 LY294002 increases expression ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of AKT1 protein CTD PMID:19457607 LY294002 decreases phosphorylation EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein CTD PMID:16179367 more ... LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein] more ... CTD PMID:15178407 more ... LY294002 decreases activity ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of AKT1 protein CTD PMID:12556562 more ... LY294002 multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[5-aminoisoquinolinone co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:11306697 more ... lycopene decreases phosphorylation ISO RGD:732909 6480464 lycopene results in decreased phosphorylation of AKT1 protein CTD PMID:17337101 malvidin multiple interactions EXP 6480464 malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein], malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:23755222 mancozeb multiple interactions EXP 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein, [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 maneb multiple interactions EXP 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein more ... CTD PMID:19883720 , PMID:23963992 manganese atom decreases expression ISO RGD:732909 6480464 Manganese results in decreased expression of AKT1 protein CTD PMID:17043766 manganese atom increases phosphorylation ISO RGD:2081 6480464 Manganese results in increased phosphorylation of AKT1 protein CTD PMID:24845367 manganese(0) decreases expression ISO RGD:732909 6480464 Manganese results in decreased expression of AKT1 protein CTD PMID:17043766 manganese(0) increases phosphorylation ISO RGD:2081 6480464 Manganese results in increased phosphorylation of AKT1 protein CTD PMID:24845367 manganese(II) chloride decreases phosphorylation ISO RGD:2081 6480464 manganese chloride results in decreased phosphorylation of AKT1 protein CTD PMID:30040983 mangiferin multiple interactions ISO RGD:2081 6480464 mangiferin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein] CTD PMID:19201465 mangiferin multiple interactions ISO RGD:732909 6480464 mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] CTD PMID:22465218 Manumycin A multiple interactions ISO RGD:2081 6480464 manumycin inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:19002579 masoprocol decreases phosphorylation ISO RGD:732909 6480464 Masoprocol results in decreased phosphorylation of AKT1 protein CTD PMID:19503098 Matrine decreases phosphorylation ISO RGD:732909 6480464 matrine results in decreased phosphorylation of AKT1 protein CTD PMID:31112718 Mecamylamine multiple interactions ISO RGD:732909 6480464 Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:12511591 Medermycin multiple interactions ISO RGD:732909 6480464 medermycin binds to and results in decreased activity of AKT1 protein CTD PMID:19309081 melatonin increases phosphorylation ISO RGD:732909 6480464 Melatonin results in increased phosphorylation of AKT1 protein CTD PMID:18078454 melatonin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:21138475 more ... melittin multiple interactions ISO RGD:732909 6480464 Melitten inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein] CTD PMID:22926441 menaquinone multiple interactions ISO RGD:2081 6480464 Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased phosphorylation of AKT1 protein] CTD PMID:27212383 mercury dichloride multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein], Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein] CTD PMID:16731823 mercury dichloride increases phosphorylation EXP 6480464 Mercuric Chloride results in increased phosphorylation of AKT1 protein CTD PMID:16731823 metformin multiple interactions ISO RGD:732909 6480464 [Metformin co-treated with IGF1 protein] results in increased phosphorylation of AKT1 protein more ... CTD PMID:16385087 more ... metformin multiple interactions ISO RGD:2081 6480464 Metformin inhibits the reaction [Testosterone results in increased phosphorylation of AKT1 protein] CTD PMID:26492952 methamphetamine increases response to substance ISO RGD:732909 6480464 AKT1 gene SNP results in increased susceptibility to Methamphetamine CTD PMID:15982448 methamphetamine multiple interactions EXP 6480464 rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein] CTD PMID:29981415 methamphetamine decreases phosphorylation EXP 6480464 Methamphetamine results in decreased phosphorylation of AKT1 protein CTD PMID:29981415 methapyrilene decreases methylation ISO RGD:732909 6480464 Methapyrilene results in decreased methylation of AKT1 intron CTD PMID:30157460 methimazole decreases phosphorylation EXP 6480464 Methimazole results in decreased phosphorylation of AKT1 protein CTD PMID:29990518 methimazole multiple interactions ISO RGD:732909 6480464 Methimazole inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:29990518 methimazole decreases phosphorylation ISO RGD:732909 6480464 Methimazole results in decreased phosphorylation of AKT1 protein CTD PMID:29990518 methotrexate increases expression ISO RGD:732909 6480464 Methotrexate results in increased expression of AKT1 mRNA CTD PMID:21678067 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of AKT1 mRNA CTD PMID:20829426 methyl caffeate decreases phosphorylation ISO RGD:732909 6480464 methyl caffeate analog results in decreased phosphorylation of AKT1 protein CTD PMID:25481497 methyl pyruvate multiple interactions EXP 6480464 methyl pyruvate inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] CTD PMID:15806154 methylarsonic acid multiple interactions ISO RGD:732909 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of AKT1 mRNA CTD PMID:23192986 methylglyoxal multiple interactions ISO RGD:732909 6480464 resveratrol inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of AKT1 protein] CTD PMID:22917016 methylglyoxal decreases phosphorylation ISO RGD:732909 6480464 Pyruvaldehyde results in decreased phosphorylation of AKT1 protein CTD PMID:22917016 methyllycaconitine multiple interactions ISO RGD:732909 6480464 AKT1 mutant form inhibits the reaction [methyllycaconitine results in increased expression of SRR protein], methyllycaconitine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:12511591 , PMID:24012499 methyllycaconitine increases phosphorylation ISO RGD:732909 6480464 methyllycaconitine results in increased phosphorylation of AKT1 protein CTD PMID:24012499 methylmercury chloride increases phosphorylation ISO RGD:2081 6480464 methylmercuric chloride results in increased phosphorylation of AKT1 protein CTD PMID:28736149 methylmercury chloride multiple interactions EXP 6480464 AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased cleavage of ATF6 protein] more ... CTD PMID:31330229 methylseleninic acid multiple interactions ISO RGD:732909 6480464 [methylselenic acid results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin more ... CTD PMID:17339365 methylseleninic acid decreases phosphorylation ISO RGD:732909 6480464 methylselenic acid results in decreased phosphorylation of AKT1 protein CTD PMID:15845651 , PMID:17339365 methylseleninic acid decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to methylselenic acid CTD PMID:15845651 metoprolol increases phosphorylation ISO RGD:2081 6480464 Metoprolol results in increased phosphorylation of AKT1 protein CTD PMID:18703049 mevinphos increases phosphorylation ISO RGD:2081 6480464 Mevinphos results in increased phosphorylation of AKT1 protein CTD PMID:25449601 microcystin-LR increases phosphorylation ISO RGD:732909 6480464 cyanoginosin LR results in increased phosphorylation of AKT1 protein CTD PMID:26506538 microcystin-LR decreases expression EXP 6480464 cyanoginosin LR results in decreased expression of AKT1 mRNA, cyanoginosin LR results in decreased expression of AKT1 protein CTD PMID:29777831 microcystin-LR increases phosphorylation EXP 6480464 cyanoginosin LR results in increased phosphorylation of AKT1 protein CTD PMID:29777831 microcystin-LR multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of AKT1 protein] CTD PMID:26506538 mifepristone multiple interactions ISO RGD:2081 6480464 Mifepristone inhibits the reaction [Dexamethasone results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:15187100 more ... mitomycin C decreases expression ISO RGD:732909 6480464 Mitomycin results in decreased expression of AKT1 protein modified form CTD PMID:16186332 MK-2206 decreases phosphorylation ISO RGD:732909 6480464 MK 2206 results in decreased phosphorylation of AKT1 protein CTD PMID:22885370 more ... MK-2206 multiple interactions ISO RGD:732909 6480464 [gamma-mangostin co-treated with MK 2206] results in decreased phosphorylation of AKT1 protein more ... CTD PMID:24685774 more ... MK-2206 multiple interactions ISO RGD:2081 6480464 MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of and results in increased expression of AKT1 protein], MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] CTD PMID:25597859 , PMID:29669060 MK-2206 decreases phosphorylation EXP 6480464 MK 2206 results in decreased phosphorylation of AKT1 protein CTD PMID:22949526 , PMID:30723155 MK-2206 multiple interactions EXP 6480464 LEPR affects the reaction [MK 2206 results in decreased phosphorylation of AKT1 protein] CTD PMID:22949526 mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 AKT1 protein affects the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of BCL2L1 mRNA] more ... CTD PMID:18755736 , PMID:31009676 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:2081 6480464 mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:28526321 mono(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased phosphorylation of AKT1 protein CTD PMID:18755736 mono(2-ethylhexyl) phthalate increases activity EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased activity of AKT1 protein CTD PMID:18755736 mono(2-ethylhexyl) phthalate affects response to substance EXP 6480464 AKT1 protein affects the susceptibility to mono-(2-ethylhexyl)phthalate CTD PMID:18755736 Monobutylphthalate affects expression ISO RGD:2081 6480464 monobutyl phthalate affects the expression of AKT1 mRNA CTD PMID:20864626 monocrotaline decreases phosphorylation ISO RGD:2081 6480464 Monocrotaline results in decreased phosphorylation of AKT1 protein CTD PMID:18801959 monocrotaline multiple interactions ISO RGD:2081 6480464 Monocrotaline affects the expression of and affects the phosphorylation of AKT1 protein more ... CTD PMID:25460361 monodansylcadaverine decreases phosphorylation ISO RGD:732909 6480464 monodansylcadaverine results in decreased phosphorylation of AKT1 protein CTD PMID:16170020 morin multiple interactions ISO RGD:2081 6480464 morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of AKT1 protein], morin inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of AKT1 protein] CTD PMID:19201465 , PMID:26767949 morin increases expression ISO RGD:732909 6480464 morin results in increased expression of AKT1 mRNA CTD PMID:28689916 morphine multiple interactions ISO RGD:732909 6480464 ARRB2 protein inhibits the reaction [Morphine results in decreased expression of AKT1 protein modified form] CTD PMID:19239323 morphine increases expression EXP 6480464 Morphine results in increased expression of AKT1 protein modified form CTD PMID:20600172 morphine decreases expression ISO RGD:732909 6480464 Morphine results in decreased expression of AKT1 protein modified form CTD PMID:19239323 morphine multiple interactions EXP 6480464 Naloxone inhibits the reaction [Morphine results in increased expression of AKT1 protein modified form] CTD PMID:20600172 morpholines decreases phosphorylation ISO RGD:732909 6480464 Morpholines analog results in decreased phosphorylation of AKT1 protein CTD PMID:24875536 morpholines multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [Morpholines analog results in decreased phosphorylation of AKT1 protein] CTD PMID:24875536 mycophenolic acid increases expression ISO RGD:732909 6480464 Mycophenolic Acid results in increased expression of AKT1 protein CTD PMID:21396949 myo-inositol hexakisphosphate decreases activity ISO RGD:732909 6480464 Phytic Acid results in decreased activity of AKT1 protein CTD PMID:15868430 myrtenal multiple interactions ISO RGD:2081 6480464 myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein] CTD PMID:27417257 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:732909 6480464 SB 203580 inhibits the reaction [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the phosphorylation of AKT1 protein] CTD PMID:17640974 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide affects phosphorylation ISO RGD:732909 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the phosphorylation of AKT1 protein CTD PMID:17640974 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases activity ISO RGD:732909 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of AKT1 protein CTD PMID:10998351 N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide multiple interactions EXP 6480464 N-(3, 5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [Particulate Matter results in decreased phosphorylation of and results in decreased expression of AKT1 protein] CTD PMID:29635361 N-acetyl-L-cysteine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein] more ... CTD PMID:12168106 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein] more ... CTD PMID:16137721 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:2081 6480464 Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:21195169 more ... N-acetylsphingosine multiple interactions ISO RGD:732909 6480464 BCL2 protein inhibits the reaction [N-acetylsphingosine results in decreased phosphorylation of and results in decreased activity of AKT1 protein] more ... CTD PMID:12640124 , PMID:16215670 N-acetylsphingosine decreases phosphorylation ISO RGD:732909 6480464 N-acetylsphingosine results in decreased phosphorylation of AKT1 protein CTD PMID:21821001 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein] more ... CTD PMID:24449419 , PMID:24933620 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKT1 protein CTD PMID:24933620 N-formyl-L-methionyl-L-leucyl-L-phenylalanine increases phosphorylation ISO RGD:732909 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of AKT1 protein CTD PMID:15925284 N-formyl-L-methionyl-L-leucyl-L-phenylalanine increases phosphorylation EXP 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of AKT1 protein CTD PMID:16621998 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO RGD:732909 6480464 resveratrol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of AKT1 protein] CTD PMID:15925284 N-methyl-4-phenylpyridinium decreases phosphorylation ISO RGD:2081 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of AKT1 protein CTD PMID:15247282 , PMID:21800153 N-methyl-4-phenylpyridinium decreases activity EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased activity of AKT1 protein CTD PMID:22891246 N-methyl-4-phenylpyridinium increases activity ISO RGD:2081 6480464 1-Methyl-4-phenylpyridinium results in increased activity of AKT1 protein CTD PMID:26048653 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of AKT1 mRNA] CTD PMID:12710931 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Selegiline co-treated with 1-Methyl-4-phenylpyridinium] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:21800153 more ... N-methyl-N-nitrosourea multiple interactions ISO RGD:2081 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of AKT1 protein more ... CTD PMID:15581186 more ... N-nitrosodiethylamine increases phosphorylation ISO RGD:2081 6480464 Diethylnitrosamine results in increased phosphorylation of AKT1 protein CTD PMID:30779474 N-nitrosodiethylamine multiple interactions ISO RGD:2081 6480464 Hesperidin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein], neferine inhibits the reaction [Diethylnitrosamine results in increased expression of AKT1 mRNA] CTD PMID:30423403 , PMID:30779474 N-nitrosodiethylamine increases phosphorylation EXP 6480464 Diethylnitrosamine results in increased phosphorylation of AKT1 protein CTD PMID:20583210 N-nitrosodiethylamine increases expression ISO RGD:2081 6480464 Diethylnitrosamine results in increased expression of AKT1, Diethylnitrosamine results in increased expression of AKT1 mRNA CTD PMID:17055752 , PMID:30423403 N-nitrosodiethylamine multiple interactions EXP 6480464 CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein], Diethylnitrosamine inhibits the reaction [Cholic Acid results in increased activity of and results in increased phosphorylation of AKT1 protein] CTD PMID:20583210 , PMID:27151938 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO RGD:732909 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein] CTD PMID:17136479 N-Vinyl-2-pyrrolidone multiple interactions ISO RGD:2081 6480464 [N-vinyl-2-pyrrolidinone binds to N-vinyl-2-pyrrolidinone] which results in increased expression of AKT1 mRNA CTD PMID:22037397 NAD zwitterion multiple interactions ISO RGD:732909 6480464 6-chloro-2 more ... CTD PMID:25536389 NAD(+) multiple interactions ISO RGD:732909 6480464 6-chloro-2 more ... CTD PMID:25536389 naloxone multiple interactions EXP 6480464 Naloxone inhibits the reaction [Morphine results in increased expression of AKT1 protein modified form] CTD PMID:20600172 naphthalene affects response to substance EXP 6480464 AKT1 affects the susceptibility to naphthalene CTD PMID:22122896 naphthalene multiple interactions EXP 6480464 [naphthalene co-treated with AKT1] results in increased expression of EIF4E protein, [naphthalene co-treated with AKT1] results in increased phosphorylation of EIF4E protein CTD PMID:22122896 naringin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:19810018 more ... naringin multiple interactions EXP 6480464 naringin inhibits the reaction [Dexamethasone results in decreased phosphorylation of AKT1 protein], naringin inhibits the reaction [Dexamethasone results in increased expression of AKT1 mRNA] CTD PMID:30878453 naringin increases phosphorylation ISO RGD:2081 6480464 naringin results in increased phosphorylation of AKT1 protein CTD PMID:25773745 , PMID:29510123 neoastilbin multiple interactions ISO RGD:732909 6480464 astilbin inhibits the reaction [Cisplatin results in decreased phosphorylation of AKT1 protein] CTD PMID:29471006 nickel atom multiple interactions EXP 6480464 Nickel promotes the reaction [Particulate Matter results in decreased phosphorylation of AKT1 protein] CTD PMID:23788629 nickel atom multiple interactions ISO RGD:732909 6480464 [nickel chloride results in increased abundance of Nickel] which results in increased phosphorylation of AKT1 protein CTD PMID:30724446 nickel dichloride multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [nickel chloride results in increased phosphorylation of AKT1 protein] more ... CTD PMID:21837363 more ... nickel dichloride decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to nickel chloride CTD PMID:23828460 nickel dichloride multiple interactions EXP 6480464 AKT1 protein affects the reaction [nickel chloride results in increased expression of HIF1A protein], AKT1 protein affects the reaction [nickel chloride results in increased expression of NDRG1 protein] CTD PMID:14729612 nickel dichloride increases phosphorylation EXP 6480464 nickel chloride results in increased phosphorylation of AKT1 protein CTD PMID:14729612 nickel dichloride increases phosphorylation ISO RGD:732909 6480464 nickel chloride results in increased phosphorylation of AKT1 protein CTD PMID:21837363 nickel subsulfide multiple interactions EXP 6480464 AKT1 protein affects the reaction [nickel subsulfide results in increased expression of HIF1A protein], AKT1 protein affects the reaction [nickel subsulfide results in increased expression of NDRG1 protein] CTD PMID:14729612 nickel subsulfide increases phosphorylation EXP 6480464 nickel subsulfide results in increased phosphorylation of AKT1 protein CTD PMID:14729612 nickel sulfate increases phosphorylation EXP 6480464 nickel sulfate results in increased phosphorylation of AKT1 protein CTD PMID:23445166 Niclosamide multiple interactions ISO RGD:732909 6480464 Niclosamide inhibits the reaction [TNF protein results in increased activity of AKT1 protein], Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of AKT1 protein] CTD PMID:20215516 , PMID:26792726 Niclosamide increases expression ISO RGD:732909 6480464 Niclosamide results in increased expression of AKT1 mRNA CTD PMID:29843133 nicotine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:12511591 more ... nicotine increases phosphorylation ISO RGD:732909 6480464 Nicotine results in increased phosphorylation of AKT1 protein CTD PMID:30836163 nicotine increases phosphorylation ISO RGD:2081 6480464 Nicotine results in increased phosphorylation of AKT1 protein CTD PMID:15983034 nicotine increases expression ISO RGD:732909 6480464 Nicotine results in increased expression of AKT1 protein modified form CTD PMID:20727180 nicotinic acid multiple interactions ISO RGD:2081 6480464 [Niacin co-treated with Chromium] results in increased phosphorylation of AKT1 protein CTD PMID:19027847 nifedipine decreases expression ISO RGD:732909 6480464 Nifedipine results in decreased expression of AKT1 protein modified form CTD PMID:20530298 nifedipine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:20562903 nilutamide increases expression EXP 6480464 nilutamide results in increased expression of AKT1 protein CTD PMID:16616092 nitric oxide multiple interactions ISO RGD:2081 6480464 AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Nitric Oxide] CTD PMID:18245901 nitroprusside increases phosphorylation ISO RGD:2081 6480464 Nitroprusside results in increased phosphorylation of AKT1 protein CTD PMID:18276108 nitroprusside increases phosphorylation ISO RGD:732909 6480464 Nitroprusside results in increased phosphorylation of AKT1 protein CTD PMID:30296409 nitroprusside multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cilomilast promotes the reaction [Nitroprusside results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:18276108 nitroprusside multiple interactions ISO RGD:732909 6480464 [Nitroprusside results in increased expression of ITGB3 protein] which results in increased phosphorylation of and results in increased activity of AKT1 protein more ... CTD PMID:21332719 , PMID:30296409 nobiletin multiple interactions ISO RGD:732909 6480464 [nobiletin co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein CTD PMID:29687528 Nonylphenol decreases expression ISO RGD:2081 6480464 nonylphenol results in decreased expression of AKT1 mRNA CTD PMID:27832966 novobiocin increases degradation ISO RGD:732909 6480464 Novobiocin analog results in increased degradation of AKT1 protein CTD PMID:20711301 NSC 23766 multiple interactions ISO RGD:732909 6480464 NSC 23766 inhibits the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein] CTD PMID:31018152 nystatin multiple interactions ISO RGD:732909 6480464 Nystatin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 o-anisidine decreases expression ISO RGD:732909 6480464 2-anisidine results in decreased expression of AKT1 mRNA CTD PMID:28089782 o-cresol multiple interactions ISO RGD:2081 6480464 Sodium Selenite inhibits the reaction [2-cresol results in increased expression of AKT1 mRNA] CTD PMID:21705299 o-cresol increases expression ISO RGD:2081 6480464 2-cresol results in increased expression of AKT1 mRNA CTD PMID:21705299 Obacunone multiple interactions ISO RGD:732909 6480464 obacunone results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:25592883 Obacunone decreases expression ISO RGD:732909 6480464 obacunone results in decreased expression of AKT1 protein modified form CTD PMID:25592883 obeticholic acid decreases expression ISO RGD:732909 6480464 obeticholic acid results in decreased expression of AKT1 mRNA CTD PMID:27939613 obeticholic acid multiple interactions EXP 6480464 obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of AKT1 protein] CTD PMID:27865854 ochratoxin A increases expression ISO RGD:2081 6480464 ochratoxin A results in increased expression of AKT1 mRNA CTD PMID:16251485 ochratoxin A increases phosphorylation EXP 6480464 ochratoxin A results in increased phosphorylation of AKT1 protein CTD PMID:23172667 ochratoxin A increases phosphorylation ISO RGD:732909 6480464 ochratoxin A results in increased phosphorylation of AKT1 protein CTD PMID:25002221 , PMID:31154016 ochratoxin A multiple interactions ISO RGD:732909 6480464 5-((2 more ... CTD PMID:25002221 , PMID:30287338 octadecanoic acid multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [stearic acid results in increased phosphorylation of AKT1 protein] more ... CTD PMID:23880231 octadecanoic acid increases phosphorylation ISO RGD:732909 6480464 stearic acid results in increased phosphorylation of AKT1 protein CTD PMID:23880231 okadaic acid multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid results in decreased phosphorylation of AKT1 protein]], Quercetin inhibits the reaction [Okadaic Acid results in decreased phosphorylation of AKT1 protein] CTD PMID:27050422 okadaic acid increases phosphorylation ISO RGD:2081 6480464 Okadaic Acid results in increased phosphorylation of AKT1 protein CTD PMID:26437446 okadaic acid multiple interactions ISO RGD:732909 6480464 Okadaic Acid inhibits the reaction [Amiloride results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:16059913 more ... okadaic acid decreases phosphorylation EXP 6480464 Okadaic Acid results in decreased phosphorylation of AKT1 protein CTD PMID:27050422 olanzapine increases expression ISO RGD:732909 6480464 olanzapine results in increased expression of AKT1 mRNA, olanzapine results in increased expression of AKT1 protein CTD PMID:19440698 olanzapine increases response to substance ISO RGD:732909 6480464 AKT1 gene SNP results in increased susceptibility to olanzapine CTD PMID:21187413 olanzapine increases phosphorylation ISO RGD:732909 6480464 olanzapine results in increased phosphorylation of AKT1 protein CTD PMID:19440698 olaparib multiple interactions ISO RGD:732909 6480464 olaparib promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein], olaparib promotes the reaction [Nitroprusside results in increased phosphorylation of AKT1 protein] CTD PMID:30296409 oleanolic acid multiple interactions ISO RGD:2081 6480464 [Fructose co-treated with Oleanolic Acid] results in increased expression of AKT1 mRNA CTD PMID:24704288 oleanolic acid increases phosphorylation ISO RGD:732909 6480464 Oleanolic Acid analog results in increased phosphorylation of AKT1 protein CTD PMID:26612655 oleic acid multiple interactions ISO RGD:2081 6480464 Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:14604813 oleic acid decreases phosphorylation ISO RGD:732909 6480464 Oleic Acid results in decreased phosphorylation of AKT1 protein CTD PMID:25536389 oleic acid multiple interactions ISO RGD:732909 6480464 6-chloro-2 more ... CTD PMID:25536389 oligopeptide decreases phosphorylation ISO RGD:732909 6480464 Oligopeptides analog results in decreased phosphorylation of AKT1 protein CTD PMID:24875536 oligopeptide multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Oligopeptides analog results in decreased phosphorylation of AKT1 protein], Acetylcysteine inhibits the reaction [Oligopeptides analog results in decreased phosphorylation of AKT1 protein] CTD PMID:24875536 olmesartan multiple interactions ISO RGD:2081 6480464 [Pravastatin co-treated with olmesartan] results in increased phosphorylation of AKT1 protein CTD PMID:17170375 Olprinone hydrochloride increases activity ISO RGD:2081 6480464 olprinone results in increased activity of AKT1 protein CTD PMID:19387321 Olprinone hydrochloride multiple interactions ISO RGD:2081 6480464 zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of AKT1 protein] CTD PMID:19387321 organoselenium compound multiple interactions ISO RGD:2081 6480464 Organoselenium Compounds inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:18538761 organoselenium compound multiple interactions ISO RGD:732909 6480464 [Organoselenium Compounds binds to Copper] which results in decreased expression of AKT1 protein CTD PMID:25167922 orotic acid multiple interactions ISO RGD:732909 6480464 Orotic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein], PIK3CA protein inhibits the reaction [Orotic Acid inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]] CTD PMID:25601987 osimertinib multiple interactions ISO RGD:732909 6480464 osimertinib affects the reaction [EGF protein results in increased phosphorylation of AKT1 protein] more ... CTD PMID:30623574 , PMID:30993382 OSU-03012 decreases phosphorylation ISO RGD:732909 6480464 OSU 03012 results in decreased phosphorylation of AKT1 protein CTD PMID:15205346 OSU-03012 decreases response to substance ISO RGD:732909 6480464 AKT1 protein modified form results in decreased susceptibility to OSU 03012 CTD PMID:15205346 oxaliplatin affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to oxaliplatin CTD PMID:19147571 oxaliplatin increases phosphorylation ISO RGD:732909 6480464 oxaliplatin results in increased phosphorylation of AKT1 protein CTD PMID:19147571 oxaliplatin multiple interactions ISO RGD:732909 6480464 oxaliplatin results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:18790786 oxidopamine multiple interactions ISO RGD:2081 6480464 Clenbuterol inhibits the reaction [Oxidopamine results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:16339297 , PMID:21397656 oxidopamine decreases phosphorylation ISO RGD:2081 6480464 Oxidopamine results in decreased phosphorylation of AKT1 protein CTD PMID:16339297 ozone increases phosphorylation ISO RGD:732909 6480464 Ozone results in increased phosphorylation of AKT1 protein CTD PMID:19536146 ozone multiple interactions ISO RGD:2081 6480464 [Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA CTD PMID:18636392 p-menthan-3-ol decreases expression ISO RGD:732909 6480464 Menthol results in decreased expression of AKT1 mRNA CTD PMID:26760959 paclitaxel multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Paclitaxel results in increased activity of AKT1 protein] more ... CTD PMID:10075725 more ... paclitaxel increases phosphorylation ISO RGD:732909 6480464 Paclitaxel results in increased phosphorylation of AKT1 protein CTD PMID:19426673 , PMID:27769712 paclitaxel decreases response to substance ISO RGD:732909 6480464 AKT1 protein results in decreased susceptibility to Paclitaxel CTD PMID:16782806 paclitaxel increases activity ISO RGD:732909 6480464 Paclitaxel results in increased activity of AKT1 protein CTD PMID:16211241 paclitaxel affects response to substance ISO RGD:732909 6480464 AKT1 protein affects the susceptibility to Paclitaxel CTD PMID:18071906 paclitaxel decreases phosphorylation ISO RGD:732909 6480464 Paclitaxel results in decreased phosphorylation of AKT1 protein CTD PMID:17404021 , PMID:23956100 Paeonol multiple interactions EXP 6480464 paeonol inhibits the reaction [Epirubicin results in decreased phosphorylation of AKT1 protein] CTD PMID:26646421 Paeonol multiple interactions ISO RGD:2081 6480464 paeonol inhibits the reaction [Epirubicin results in increased phosphorylation of AKT1 protein] CTD PMID:29505745 palbociclib multiple interactions ISO RGD:732909 6480464 BMS 754807 inhibits the reaction [palbociclib results in increased phosphorylation of AKT1 protein], palbociclib promotes the reaction [idelalisib results in decreased phosphorylation of AKT1 protein] CTD PMID:23676220 , PMID:24986516 palbociclib increases phosphorylation ISO RGD:732909 6480464 palbociclib results in increased phosphorylation of AKT1 protein CTD PMID:24986516 panobinostat multiple interactions ISO RGD:732909 6480464 [Bortezomib co-treated with panobinostat] results in decreased activity of AKT1 protein CTD PMID:18445700 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of AKT1 mRNA CTD PMID:17562736 paracetamol increases activity ISO RGD:2081 6480464 Acetaminophen results in increased activity of AKT1 protein CTD PMID:25858767 paracetamol increases phosphorylation EXP 6480464 Acetaminophen results in increased phosphorylation of AKT1 protein CTD PMID:25752611 paracetamol multiple interactions EXP 6480464 PRKN gene mutant form affects the reaction [Acetaminophen results in increased phosphorylation of AKT1 protein] CTD PMID:25752611 paracetamol multiple interactions ISO RGD:2081 6480464 morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of AKT1 protein] CTD PMID:26767949 paracetamol decreases phosphorylation ISO RGD:2081 6480464 Acetaminophen results in decreased phosphorylation of AKT1 protein CTD PMID:26767949 paracetamol affects expression ISO RGD:2081 6480464 Acetaminophen affects the expression of AKT1 mRNA CTD PMID:16701773 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of AKT1 mRNA CTD PMID:16797015 paraquat affects phosphorylation ISO RGD:732909 6480464 Paraquat affects the phosphorylation of AKT1 protein CTD PMID:28428137 paraquat multiple interactions ISO RGD:732909 6480464 ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein] CTD PMID:28428137 paraquat affects phosphorylation EXP 6480464 Paraquat affects the phosphorylation of AKT1 protein CTD PMID:28428137 paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA more ... CTD PMID:23898955 more ... Parthenin decreases phosphorylation ISO RGD:732909 6480464 parthenin analog results in decreased phosphorylation of AKT1 protein CTD PMID:25196075 Parthenin multiple interactions ISO RGD:732909 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [parthenin analog results in decreased phosphorylation of AKT1 protein] CTD PMID:25196075 patulin decreases phosphorylation ISO RGD:732909 6480464 Patulin results in decreased phosphorylation of AKT1 protein CTD PMID:29604266 patulin multiple interactions ISO RGD:732909 6480464 Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of AKT1 protein] CTD PMID:29604266 Paxilline multiple interactions ISO RGD:732909 6480464 paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]] CTD PMID:12807996 PD 0325901 multiple interactions ISO RGD:732909 6480464 PD 0325901 promotes the reaction [dactolisib results in decreased phosphorylation of AKT1 protein] CTD PMID:22415236 PD 168393 multiple interactions ISO RGD:2081 6480464 PD168393 inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] CTD PMID:25398788 pentobarbital multiple interactions ISO RGD:2081 6480464 Pentobarbital results in decreased activity of and results in decreased phosphorylation of AKT1 protein CTD PMID:19346066 Pepstatin multiple interactions ISO RGD:732909 6480464 pepstatin inhibits the reaction [AKT1 protein modified form results in increased susceptibility to Etoposide] CTD PMID:17699715 perfluorodecanoic acid decreases phosphorylation ISO RGD:732909 6480464 perfluorodecanoic acid results in decreased phosphorylation of AKT1 protein CTD PMID:19135466 perfluorononanoic acid decreases expression ISO RGD:2081 6480464 perfluoro-n-nonanoic acid results in decreased expression of AKT1 protein modified form CTD PMID:22387981 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 perfluorooctane sulfonic acid promotes the reaction [ITPR1 protein binds to AKT1 protein] CTD PMID:28288859 perfluorooctane-1-sulfonic acid increases phosphorylation EXP 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of AKT1 protein CTD PMID:28288859 perifosine multiple interactions ISO RGD:732909 6480464 [perifosine co-treated with Butyrates] results in decreased activity of AKT1 protein more ... CTD PMID:15781658 , PMID:30265530 perifosine decreases phosphorylation ISO RGD:732909 6480464 perifosine results in decreased phosphorylation of AKT1 protein CTD PMID:31445927 perifosine multiple interactions EXP 6480464 [perifosine co-treated with temsirolimus] results in decreased activity of AKT1 protein CTD PMID:21267448 permethrin multiple interactions EXP 6480464 Permethrin inhibits the reaction [INS1 protein results in increased expression of and results in increased phosphorylation of AKT1 protein], Permethrin results in decreased expression of and results in increased phosphorylation of AKT1 protein CTD PMID:24911977 peroxynitrous acid multiple interactions ISO RGD:2081 6480464 BDNF protein promotes the reaction [Peroxynitrous Acid results in increased phosphorylation of AKT1 protein] more ... CTD PMID:17302912 peroxynitrous acid increases phosphorylation ISO RGD:2081 6480464 Peroxynitrous Acid results in increased phosphorylation of AKT1 protein CTD PMID:17302912 PHA-665752 multiple interactions ISO RGD:732909 6480464 5-((2 more ... CTD PMID:22040890 , PMID:25002221 phenformin increases phosphorylation EXP 6480464 Phenformin results in increased phosphorylation of AKT1 protein CTD PMID:19901985 phenobarbital increases expression ISO RGD:2081 6480464 Phenobarbital results in increased expression of AKT1 mRNA CTD PMID:22037397 phenol red multiple interactions ISO RGD:732909 6480464 Phenolsulfonphthalein results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:17203231 phenylephrine multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of AKT1 protein] CTD PMID:10679475 phenylephrine increases phosphorylation ISO RGD:2081 6480464 Phenylephrine results in increased phosphorylation of AKT1 protein CTD PMID:28759639 phenylephrine multiple interactions ISO RGD:2081 6480464 GRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of AKT1 protein] CTD PMID:28759639 phenylephrine increases phosphorylation EXP 6480464 Phenylephrine results in increased phosphorylation of AKT1 protein CTD PMID:10679475 phenylephrine affects phosphorylation ISO RGD:2081 6480464 Phenylephrine affects the phosphorylation of AKT1 protein CTD PMID:18084315 phloroglucinol decreases phosphorylation ISO RGD:732909 6480464 Phloroglucinol analog results in decreased phosphorylation of AKT1 protein CTD PMID:23178381 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of AKT1 protein more ... CTD PMID:20660715 , PMID:27432484 phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:732909 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein CTD PMID:20438634 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:732909 6480464 kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] more ... CTD PMID:20438634 more ... phorbol 13-acetate 12-myristate increases phosphorylation EXP 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein CTD PMID:20172950 phosphatidic acid multiple interactions EXP 6480464 alpha-cyano-(3, 4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of AKT1 protein] CTD PMID:16354768 phosphatidic acid multiple interactions ISO RGD:2081 6480464 R 59949 inhibits the reaction [Phosphatidic Acids results in increased phosphorylation of AKT1 protein] CTD PMID:15525798 phosphonoformic acid multiple interactions ISO RGD:732909 6480464 Foscarnet inhibits the reaction [Phosphates results in decreased expression of AKT1 mRNA] CTD PMID:23308213 phosphoramidon multiple interactions ISO RGD:732909 6480464 phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:15177934 phylloquinone multiple interactions ISO RGD:2081 6480464 [Warfarin co-treated with Vitamin K 1] results in decreased phosphorylation of AKT1 protein, Vitamin K 2 inhibits the reaction [[Warfarin co-treated with Vitamin K 1] results in decreased phosphorylation of AKT1 protein] CTD PMID:27212383 phytoestrogen increases phosphorylation ISO RGD:2081 6480464 Phytoestrogens results in increased phosphorylation of AKT1 protein CTD PMID:24726523 picropodophyllotoxin multiple interactions ISO RGD:732909 6480464 picropodophyllin inhibits the reaction [Cadmium Chloride results in increased cleavage of AKT1 protein] CTD PMID:25118938 piperine multiple interactions EXP 6480464 piperine inhibits the reaction [IL2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:25655587 pirinixic acid multiple interactions ISO RGD:2081 6480464 pirinixic acid results in increased expression of and results in increased phosphorylation of AKT1 protein CTD PMID:19151258 Plantamajoside multiple interactions EXP 6480464 plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein] CTD PMID:31009642 Plantamajoside multiple interactions ISO RGD:2081 6480464 plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of AKT1 protein] CTD PMID:31009642 platycodin D increases phosphorylation EXP 6480464 platycodin D results in increased phosphorylation of AKT1 protein CTD PMID:21847688 platycodin D decreases activity ISO RGD:732909 6480464 platycodin D results in decreased activity of AKT1 protein CTD PMID:18093727 platycodin D multiple interactions ISO RGD:2081 6480464 platycodin D inhibits the reaction [TNFSF11 protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:27739107 platycodin D multiple interactions ISO RGD:732909 6480464 [platycodin D co-treated with Imatinib Mesylate] results in decreased phosphorylation of and results in decreased expression of AKT1 protein, [platycodin D results in decreased activity of AKT1 protein] which results in decreased phosphorylation of and results in decreased localization of TERT protein CTD PMID:18093727 , PMID:29552859 platycodin D affects expression ISO RGD:732909 6480464 platycodin D affects the expression of AKT1 protein modified form CTD PMID:25532840 platycodin D decreases expression ISO RGD:732909 6480464 platycodin D results in decreased expression of AKT1 protein modified form CTD PMID:24048756 , PMID:26078792 platycodin D decreases phosphorylation ISO RGD:732909 6480464 platycodin D results in decreased phosphorylation of AKT1 protein CTD PMID:25250884 , PMID:26078792 plitidepsin multiple interactions ISO RGD:732909 6480464 AKT1 protein affects the reaction [plitidepsin results in increased activity of MAPK8 protein], plitidepsin results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:18089842 plumbagin increases phosphorylation ISO RGD:732909 6480464 plumbagin results in increased phosphorylation of AKT1 protein CTD PMID:20028456 Polygodial decreases phosphorylation ISO RGD:2081 6480464 polygodial results in decreased phosphorylation of AKT1 protein CTD PMID:27645309 ponatinib multiple interactions ISO RGD:732909 6480464 (+)-JQ1 compound promotes the reaction [ponatinib results in decreased phosphorylation of AKT1 protein], ponatinib promotes the reaction [(+)-JQ1 compound results in decreased phosphorylation of AKT1 protein] CTD PMID:25053825 ponatinib decreases phosphorylation ISO RGD:732909 6480464 ponatinib results in decreased phosphorylation of AKT1 protein CTD PMID:25053825 , PMID:25304212 potassium dichromate multiple interactions ISO RGD:2081 6480464 Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein] CTD PMID:21262251 potassium dichromate increases expression ISO RGD:732909 6480464 Potassium Dichromate results in increased expression of AKT1 protein CTD PMID:23718831 potassium dichromate decreases phosphorylation ISO RGD:2081 6480464 Potassium Dichromate results in decreased phosphorylation of AKT1 protein CTD PMID:21262251 pravastatin multiple interactions EXP 6480464 Pravastatin inhibits the reaction [Carboplatin results in increased activity of and results in increased phosphorylation of AKT1 protein] CTD PMID:18483861 pravastatin multiple interactions ISO RGD:2081 6480464 [Pravastatin co-treated with olmesartan] results in increased phosphorylation of AKT1 protein, [resveratrol co-treated with Pravastatin] results in increased phosphorylation of AKT1 protein CTD PMID:17170375 , PMID:17188708 pravastatin increases phosphorylation ISO RGD:2081 6480464 Pravastatin results in increased phosphorylation of AKT1 protein CTD PMID:17170375 , PMID:17188708 procyanidin B2 increases phosphorylation ISO RGD:732909 6480464 procyanidin B2 results in increased phosphorylation of AKT1 protein CTD PMID:21945981 progesterone multiple interactions ISO RGD:732909 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Progesterone results in increased phosphorylation of AKT1 protein] CTD PMID:15358673 progesterone increases phosphorylation ISO RGD:2081 6480464 Progesterone results in increased phosphorylation of AKT1 protein CTD PMID:28324061 progesterone multiple interactions ISO RGD:2081 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of AKT1 protein more ... CTD PMID:22465879 , PMID:28324061 progesterone multiple interactions EXP 6480464 Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein] CTD PMID:15845746 progesterone increases phosphorylation ISO RGD:732909 6480464 Progesterone results in increased phosphorylation of AKT1 protein CTD PMID:15358673 promegestone multiple interactions ISO RGD:2081 6480464 fulvestrant inhibits the reaction [Promegestone results in increased phosphorylation of AKT1 protein], Mifepristone inhibits the reaction [Promegestone results in increased phosphorylation of AKT1 protein] CTD PMID:16020483 promegestone increases phosphorylation ISO RGD:2081 6480464 Promegestone results in increased phosphorylation of AKT1 protein CTD PMID:16020483 propazine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [propazine results in decreased expression of and results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:27431321 propofol increases phosphorylation ISO RGD:2081 6480464 Propofol results in increased phosphorylation of AKT1 protein CTD PMID:24810525 propofol multiple interactions ISO RGD:2081 6480464 Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein] CTD PMID:24810525 propranolol decreases phosphorylation ISO RGD:732909 6480464 Propranolol results in decreased phosphorylation of AKT1 protein CTD PMID:30130526 prostaglandin E2 multiple interactions ISO RGD:732909 6480464 Dinoprostone inhibits the reaction [isoliquiritigenin results in decreased activity of AKT1 protein] more ... CTD PMID:17805209 more ... prostaglandin E2 increases phosphorylation EXP 6480464 Dinoprostone results in increased phosphorylation of AKT1 protein CTD PMID:30884126 prostaglandin E2 multiple interactions EXP 6480464 taiwanin C inhibits the reaction [Dinoprostone results in increased phosphorylation of AKT1 protein] CTD PMID:30884126 prostaglandin E2 multiple interactions ISO RGD:2081 6480464 Dinoprostone results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:16396944 prostaglandin E2 increases phosphorylation ISO RGD:732909 6480464 Dinoprostone results in increased phosphorylation of AKT1 protein CTD PMID:17805209 pterostilbene decreases expression ISO RGD:732909 6480464 pterostilbene results in decreased expression of AKT1 mRNA CTD PMID:20152895 pterostilbene multiple interactions ISO RGD:732909 6480464 pterostilbene results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:24154491 puerarin increases phosphorylation ISO RGD:732909 6480464 puerarin results in increased phosphorylation of AKT1 protein CTD PMID:21884717 puerarin multiple interactions ISO RGD:732909 6480464 fulvestrant inhibits the reaction [puerarin results in increased phosphorylation of AKT1 protein] CTD PMID:21884717 PX-866 decreases phosphorylation EXP 6480464 PX-866 results in decreased phosphorylation of AKT1 protein CTD PMID:25805502 PX-866 multiple interactions ISO RGD:732909 6480464 PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] more ... CTD PMID:28634229 PX-866 decreases phosphorylation ISO RGD:732909 6480464 PX-866 results in decreased phosphorylation of AKT1 protein CTD PMID:28634229 pyocyanine multiple interactions ISO RGD:732909 6480464 Glutathione inhibits the reaction [Pyocyanine results in increased phosphorylation of AKT1 protein], RTKI cpd inhibits the reaction [Pyocyanine results in increased phosphorylation of AKT1 protein] CTD PMID:24015256 pyocyanine increases phosphorylation ISO RGD:732909 6480464 Pyocyanine results in increased phosphorylation of AKT1 protein CTD PMID:24015256 pyrithione multiple interactions ISO RGD:2081 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of AKT1 protein, AKT1 protein promotes the reaction [[Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein] CTD PMID:17098228 pyrrolidine dithiocarbamate multiple interactions ISO RGD:732909 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [7 more ... CTD PMID:24431215 pyrvinium decreases phosphorylation EXP 6480464 pyrvinium results in decreased phosphorylation of AKT1 protein CTD PMID:27542212 pyrvinium decreases phosphorylation ISO RGD:732909 6480464 pyrvinium results in decreased phosphorylation of AKT1 protein CTD PMID:27542212 quercetagetin multiple interactions ISO RGD:2081 6480464 quercetagetin inhibits the reaction [lipoteichoic acid results in increased phosphorylation of AKT1 protein] CTD PMID:20685402 quercetin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:12826665 more ... quercetin decreases phosphorylation EXP 6480464 Quercetin results in decreased phosphorylation of AKT1 protein CTD PMID:22850125 quercetin multiple interactions ISO RGD:732909 6480464 2-methoxyestradiol inhibits the reaction [Quercetin results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:12888923 more ... quercetin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:11306697 more ... quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of AKT1 mRNA, Quercetin results in decreased expression of AKT1 protein CTD PMID:25658812 quercetin increases phosphorylation ISO RGD:2081 6480464 Quercetin results in increased phosphorylation of AKT1 protein CTD PMID:17045724 quercetin affects phosphorylation ISO RGD:732909 6480464 Quercetin affects the phosphorylation of AKT1 protein CTD PMID:24001813 quercetin decreases phosphorylation ISO RGD:732909 6480464 Quercetin results in decreased phosphorylation of AKT1 protein CTD PMID:12888923 more ... quercetin increases expression ISO RGD:732909 6480464 Quercetin results in increased expression of AKT1 mRNA CTD PMID:14715546 quercetin increases phosphorylation ISO RGD:732909 6480464 Quercetin results in increased phosphorylation of AKT1 protein CTD PMID:24275163 , PMID:26986492 quercetin decreases expression ISO RGD:732909 6480464 Quercetin results in decreased expression of AKT1 mRNA more ... CTD PMID:12653748 more ... quizartinib decreases phosphorylation ISO RGD:732909 6480464 quizartinib results in decreased phosphorylation of AKT1 protein CTD PMID:25053825 quizartinib multiple interactions ISO RGD:732909 6480464 (+)-JQ1 compound promotes the reaction [quizartinib results in decreased phosphorylation of AKT1 protein], quizartinib promotes the reaction [(+)-JQ1 compound results in decreased phosphorylation of AKT1 protein] CTD PMID:25053825 raffinose increases phosphorylation EXP 6480464 Raffinose results in increased phosphorylation of AKT1 protein CTD PMID:29458019 raffinose increases phosphorylation ISO RGD:2081 6480464 Raffinose results in increased phosphorylation of AKT1 protein CTD PMID:29458019 raloxifene decreases phosphorylation ISO RGD:732909 6480464 Raloxifene Hydrochloride results in decreased phosphorylation of AKT1 protein CTD PMID:15876410 raloxifene increases phosphorylation ISO RGD:2081 6480464 Raloxifene Hydrochloride results in increased phosphorylation of AKT1 protein CTD PMID:15590986 raloxifene increases phosphorylation ISO RGD:732909 6480464 Raloxifene Hydrochloride results in increased phosphorylation of AKT1 protein CTD PMID:16798746 razoxane increases activity ISO RGD:2081 6480464 Razoxane results in increased activity of AKT1 protein CTD PMID:18379782 reserpine multiple interactions EXP 6480464 arsenic trioxide promotes the reaction [Reserpine results in decreased phosphorylation of AKT1 protein] CTD PMID:26114099 reserpine decreases phosphorylation EXP 6480464 Reserpine results in decreased phosphorylation of AKT1 protein CTD PMID:26114099 resveratrol multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:15849355 more ... resveratrol affects binding ISO RGD:732909 6480464 resveratrol binds to AKT1 protein CTD PMID:24968355 resveratrol decreases activity ISO RGD:732909 6480464 resveratrol results in decreased activity of AKT1 protein CTD PMID:23229870 resveratrol decreases expression ISO RGD:732909 6480464 resveratrol results in decreased expression of AKT1 mRNA more ... CTD PMID:22234583 more ... resveratrol affects phosphorylation ISO RGD:732909 6480464 resveratrol affects the phosphorylation of AKT1 protein CTD PMID:24001813 resveratrol decreases phosphorylation ISO RGD:732909 6480464 resveratrol results in decreased phosphorylation of AKT1 protein CTD PMID:15829497 more ... resveratrol increases phosphorylation ISO RGD:732909 6480464 resveratrol results in increased phosphorylation of AKT1 protein CTD PMID:17499741 more ... resveratrol decreases phosphorylation ISO RGD:2081 6480464 resveratrol results in decreased phosphorylation of AKT1 protein CTD PMID:24304514 , PMID:26283207 resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of AKT1 protein CTD PMID:21980390 more ... resveratrol increases phosphorylation ISO RGD:2081 6480464 resveratrol results in increased phosphorylation of AKT1 protein CTD PMID:17188708 , PMID:17346750 resveratrol multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:15849355 more ... resveratrol multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:15925284 more ... ribavirin decreases phosphorylation ISO RGD:732909 6480464 Ribavirin results in decreased phosphorylation of AKT1 protein CTD PMID:29112301 riboflavin increases phosphorylation EXP 6480464 Riboflavin analog results in increased phosphorylation of AKT1 protein, Riboflavin results in increased phosphorylation of AKT1 protein CTD PMID:20688149 roflumilast increases phosphorylation ISO RGD:2081 6480464 Roflumilast results in increased phosphorylation of AKT1 protein CTD PMID:18276108 roflumilast multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Roflumilast promotes the reaction [Nitroprusside results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:18276108 rolipram increases phosphorylation ISO RGD:2081 6480464 Rolipram results in increased phosphorylation of AKT1 protein CTD PMID:18276108 rolipram multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Rolipram promotes the reaction [Nitroprusside results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:18276108 rosuvastatin calcium affects phosphorylation ISO RGD:2081 6480464 Rosuvastatin Calcium affects the phosphorylation of AKT1 protein CTD PMID:27815113 rotenone affects phosphorylation ISO RGD:2081 6480464 Rotenone affects the phosphorylation of AKT1 protein CTD PMID:19781600 rotenone multiple interactions EXP 6480464 Rotenone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of AKT1 protein] CTD PMID:30857887 rotenone multiple interactions ISO RGD:732909 6480464 1 more ... CTD PMID:28245986 rotenone decreases phosphorylation ISO RGD:732909 6480464 Rotenone results in decreased phosphorylation of AKT1 protein CTD PMID:28245986 rotenone increases expression EXP 6480464 Rotenone results in increased expression of AKT1 mRNA CTD PMID:26806867 rotenone decreases phosphorylation ISO RGD:2081 6480464 Rotenone results in decreased phosphorylation of AKT1 protein CTD PMID:25433145 more ... rotenone multiple interactions ISO RGD:2081 6480464 1 more ... CTD PMID:25433145 more ... rottlerin multiple interactions ISO RGD:732909 6480464 rottlerin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:15177934 rottlerin decreases phosphorylation ISO RGD:732909 6480464 rottlerin results in decreased phosphorylation of AKT1 protein CTD PMID:22902833 rottlerin decreases phosphorylation EXP 6480464 rottlerin results in decreased phosphorylation of AKT1 protein CTD PMID:19393235 rubimaillin multiple interactions ISO RGD:732909 6480464 dorsomorphin inhibits the reaction [rubimaillin results in decreased phosphorylation of AKT1 protein] CTD PMID:23466342 rubimaillin decreases phosphorylation ISO RGD:732909 6480464 rubimaillin results in decreased phosphorylation of AKT1 protein CTD PMID:23466342 Rutamarin multiple interactions EXP 6480464 rutamarin promotes the reaction [INS protein results in increased phosphorylation of AKT1 protein] CTD PMID:22384078 rutin multiple interactions ISO RGD:2081 6480464 Rutin inhibits the reaction [Fructose results in decreased phosphorylation of AKT1 protein] CTD PMID:22426011 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 Buthionine Sulfoximine promotes the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein], Buthionine Sulfoximine promotes the reaction [Cadmium results in increased phosphorylation of AKT1 protein] CTD PMID:24449419 S-nitroso-N-acetyl-D-penicillamine multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:21138475 S-nitroso-N-acetyl-D-penicillamine decreases phosphorylation EXP 6480464 S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein CTD PMID:21138475 Salidroside multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein]], rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein] CTD PMID:28465020 salubrinal multiple interactions ISO RGD:2081 6480464 salubrinal inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] CTD PMID:25398788 salvianolic acid B increases phosphorylation ISO RGD:2081 6480464 salvianolic acid B results in increased phosphorylation of AKT1 protein CTD PMID:22545124 salvianolic acid B multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvianolic acid B results in increased phosphorylation of AKT1 protein] CTD PMID:22545124 sarpogrelate multiple interactions EXP 6480464 [sarpogrelate results in increased activity of AKT1 protein] inhibits the reaction [Serotonin results in increased ubiquitination of and results in increased degradation of IRS1 protein] CTD PMID:22975078 SB 203580 multiple interactions ISO RGD:732909 6480464 SB 203580 inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of AKT1 protein] more ... CTD PMID:11788791 more ... SB 203580 decreases phosphorylation ISO RGD:732909 6480464 SB 203580 results in decreased phosphorylation of AKT1 protein CTD PMID:27032576 SB 203580 decreases activity ISO RGD:732909 6480464 SB 203580 results in decreased activity of AKT1 protein CTD PMID:10998351 SB 431542 multiple interactions ISO RGD:2081 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein] CTD PMID:23159718 SB 431542 multiple interactions EXP 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [LEPR gene mutant form results in increased phosphorylation of AKT1 protein] CTD PMID:23159718 selenium atom multiple interactions ISO RGD:732909 6480464 [Selenium results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin more ... CTD PMID:17339365 selenium atom increases phosphorylation ISO RGD:2081 6480464 Selenium results in increased phosphorylation of AKT1 protein CTD PMID:29324385 selenium atom multiple interactions ISO RGD:2081 6480464 Selenium inhibits the reaction [arsenite results in decreased expression of and results in decreased phosphorylation of AKT1 protein] CTD PMID:29324385 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein] CTD PMID:17997286 selenium atom increases expression ISO RGD:732909 6480464 Selenium results in increased expression of AKT1 mRNA CTD PMID:19244175 selenium atom decreases phosphorylation ISO RGD:732909 6480464 Selenium results in decreased phosphorylation of AKT1 protein CTD PMID:17339365 serotonin increases activity EXP 6480464 Serotonin results in increased activity of AKT1 protein CTD PMID:22975078 serotonin multiple interactions EXP 6480464 [[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein more ... CTD PMID:22975078 serpentine asbestos increases phosphorylation ISO RGD:732909 6480464 Asbestos, Serpentine results in increased phosphorylation of AKT1 protein CTD PMID:26685284 sertraline multiple interactions ISO RGD:2081 6480464 Sertraline inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:17728140 sevoflurane multiple interactions ISO RGD:2081 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sevoflurane results in increased phosphorylation of AKT1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Sevoflurane results in increased phosphorylation of AKT1 protein] CTD PMID:19881297 sevoflurane increases phosphorylation ISO RGD:2081 6480464 sevoflurane results in increased phosphorylation of AKT1 protein CTD PMID:19881297 Shikonin multiple interactions ISO RGD:732909 6480464 shikonin promotes the reaction [Oxygen deficiency results in increased phosphorylation of AKT1 protein] CTD PMID:28684144 Shikonin decreases phosphorylation ISO RGD:732909 6480464 shikonin results in decreased phosphorylation of AKT1 protein CTD PMID:24463199 sildenafil citrate increases phosphorylation ISO RGD:2081 6480464 Sildenafil Citrate results in increased phosphorylation of AKT1 protein CTD PMID:18373738 silibinin multiple interactions EXP 6480464 Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of AKT1 protein] CTD PMID:25559859 silicon dioxide decreases phosphorylation ISO RGD:2081 6480464 Silicon Dioxide analog results in decreased phosphorylation of AKT1 protein CTD PMID:27613482 simazine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simazine results in decreased expression of and results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:27431321 simazine multiple interactions EXP 6480464 Simazine results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:27431321 simvastatin decreases expression ISO RGD:732909 6480464 Simvastatin results in decreased expression of AKT1 mRNA, Simvastatin results in decreased expression of AKT1 protein CTD PMID:18031796 simvastatin decreases phosphorylation ISO RGD:732909 6480464 Simvastatin results in decreased phosphorylation of AKT1 protein CTD PMID:18031796 more ... simvastatin increases phosphorylation EXP 6480464 Simvastatin results in increased phosphorylation of AKT1 protein CTD PMID:22082490 simvastatin decreases phosphorylation EXP 6480464 Simvastatin results in decreased phosphorylation of AKT1 protein CTD PMID:22144680 , PMID:27734117 simvastatin multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:17327694 , PMID:27734117 simvastatin increases phosphorylation ISO RGD:732909 6480464 Simvastatin results in increased phosphorylation of AKT1 protein CTD PMID:20594940 simvastatin decreases activity ISO RGD:732909 6480464 Simvastatin results in decreased activity of AKT1 protein CTD PMID:21059805 simvastatin multiple interactions ISO RGD:2081 6480464 Simvastatin inhibits the reaction [Glucose results in decreased expression of AKT1 protein modified form] more ... CTD PMID:17335931 more ... simvastatin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]] more ... CTD PMID:12438947 more ... sirolimus multiple interactions ISO RGD:732909 6480464 [Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of BCL2L11 protein more ... CTD PMID:18622747 more ... sirolimus increases phosphorylation ISO RGD:2081 6480464 Sirolimus results in increased phosphorylation of AKT1 protein CTD PMID:24304514 , PMID:28108221 sirolimus increases phosphorylation ISO RGD:732909 6480464 [Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein, Sirolimus results in increased phosphorylation of AKT1 protein CTD PMID:21092744 more ... sirolimus multiple interactions ISO RGD:2081 6480464 resveratrol inhibits the reaction [Sirolimus results in increased phosphorylation of AKT1 protein], Sirolimus inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] CTD PMID:24304514 , PMID:25597859 sirolimus affects phosphorylation ISO RGD:732909 6480464 Sirolimus affects the phosphorylation of AKT1 protein CTD PMID:25758096 sirolimus decreases phosphorylation ISO RGD:732909 6480464 Sirolimus results in decreased phosphorylation of AKT1 protein CTD PMID:19176369 , PMID:21976531 sirolimus multiple interactions EXP 6480464 [Sirolimus co-treated with Resveratrol] promotes the reaction [TSC2 gene mutant form results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:15806154 more ... sirtinol multiple interactions EXP 6480464 sirtinol inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein]] CTD PMID:26450947 sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of AKT1 mRNA CTD PMID:21795629 sodium arsenite multiple interactions ISO RGD:732909 6480464 [Estradiol co-treated with sodium arsenite] results in increased phosphorylation of AKT1 protein more ... CTD PMID:12482858 more ... sodium arsenite decreases phosphorylation ISO RGD:2081 6480464 sodium arsenite results in decreased phosphorylation of AKT1 protein CTD PMID:27966075 sodium arsenite decreases phosphorylation ISO RGD:732909 6480464 sodium arsenite results in decreased phosphorylation of AKT1 protein CTD PMID:29039521 sodium arsenite decreases expression ISO RGD:2081 6480464 sodium arsenite results in decreased expression of AKT1 protein CTD PMID:29657918 , PMID:31163222 sodium arsenite increases phosphorylation ISO RGD:732909 6480464 sodium arsenite results in increased phosphorylation of AKT1 protein CTD PMID:12482858 more ... sodium arsenite multiple interactions ISO RGD:2081 6480464 [Hydrogen Peroxide co-treated with sodium arsenite] results in increased phosphorylation of AKT1 protein more ... CTD PMID:12472888 more ... sodium arsenite decreases phosphorylation EXP 6480464 sodium arsenite results in decreased phosphorylation of AKT1 protein CTD PMID:16166651 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of AKT1 mRNA CTD PMID:19822182 , PMID:31233874 sodium arsenite multiple interactions EXP 6480464 CDKN1B protein inhibits the reaction [sodium arsenite results in increased activity of AKT1 protein] more ... CTD PMID:12529330 more ... sodium arsenite increases activity ISO RGD:732909 6480464 sodium arsenite results in increased activity of AKT1 protein CTD PMID:22872060 sodium arsenite decreases expression ISO RGD:732909 6480464 sodium arsenite results in decreased expression of AKT1 mRNA CTD PMID:12760830 sodium dichromate decreases expression ISO RGD:732909 6480464 sodium bichromate results in decreased expression of AKT1 mRNA CTD PMID:12760830 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of AKT1 mRNA CTD PMID:22155349 sodium dichromate increases expression ISO RGD:2081 6480464 sodium bichromate results in increased expression of AKT1 mRNA CTD PMID:22561333 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of AKT1 mRNA CTD PMID:22155349 sodium dodecyl sulfate increases phosphorylation EXP 6480464 Sodium Dodecyl Sulfate results in increased phosphorylation of AKT1 protein CTD PMID:23445166 sodium fluoride decreases phosphorylation ISO RGD:732909 6480464 Sodium Fluoride results in decreased phosphorylation of AKT1 protein CTD PMID:21708216 sodium fluoride increases phosphorylation ISO RGD:2081 6480464 Sodium Fluoride results in increased phosphorylation of AKT1 protein CTD PMID:24300170 sodium fluoride multiple interactions ISO RGD:2081 6480464 DKK1 protein inhibits the reaction [Sodium Fluoride results in increased phosphorylation of AKT1 protein] CTD PMID:24300170 sodium nitrite increases expression ISO RGD:2081 6480464 Sodium Nitrite results in increased expression of AKT1 protein CTD PMID:28266762 sodium nitrite multiple interactions ISO RGD:2081 6480464 Carnosine inhibits the reaction [Sodium Nitrite results in increased expression of AKT1 protein] CTD PMID:28266762 solasodine decreases phosphorylation ISO RGD:732909 6480464 solasodine results in decreased phosphorylation of AKT1 protein CTD PMID:28283413 sorafenib multiple interactions ISO RGD:732909 6480464 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3 more ... CTD PMID:16985072 , PMID:23036488 sorafenib decreases phosphorylation ISO RGD:732909 6480464 sorafenib results in decreased phosphorylation of AKT1 protein CTD PMID:23036488 sphingosine 1-phosphate multiple interactions ISO RGD:732909 6480464 sphingosine 1-phosphate results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:16365044 sphingosine 1-phosphate increases phosphorylation EXP 6480464 sphingosine 1-phosphate results in increased phosphorylation of AKT1 protein CTD PMID:15946935 stattic multiple interactions ISO RGD:732909 6480464 stattic inhibits the reaction [Arsenicals results in increased phosphorylation of AKT1 protein] CTD PMID:23255093 staurosporine multiple interactions ISO RGD:732909 6480464 Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:15177934 staurosporine increases phosphorylation ISO RGD:2081 6480464 Staurosporine results in increased phosphorylation of AKT1 protein CTD PMID:11306697 staurosporine multiple interactions ISO RGD:2081 6480464 Staurosporine promotes the reaction [INS1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:11306697 stilbenoid multiple interactions ISO RGD:732909 6480464 Stilbenes analog results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:18449500 streptozocin multiple interactions ISO RGD:2081 6480464 [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein more ... CTD PMID:16595661 more ... streptozocin decreases expression ISO RGD:2081 6480464 Streptozocin results in decreased expression of AKT1 mRNA, Streptozocin results in decreased expression of AKT1 protein CTD PMID:26071184 , PMID:27417257 streptozocin decreases phosphorylation ISO RGD:2081 6480464 Streptozocin results in decreased phosphorylation of AKT1 protein CTD PMID:19002579 more ... succimer multiple interactions ISO RGD:2081 6480464 Succimer inhibits the reaction [sodium arsenite results in decreased expression of AKT1 protein] CTD PMID:31163222 sulfadimethoxine multiple interactions ISO RGD:2081 6480464 [Complex Mixtures co-treated with Sulfadimethoxine] results in increased expression of AKT1 mRNA CTD PMID:22687987 sulforaphane multiple interactions ISO RGD:732909 6480464 NGF protein inhibits the reaction [sulforafan results in decreased phosphorylation of AKT1 protein], sulforafan results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:15896333 , PMID:29407470 sulforaphane increases phosphorylation ISO RGD:732909 6480464 sulforafan results in increased phosphorylation of AKT1 protein CTD PMID:30965051 sulforaphane decreases phosphorylation ISO RGD:732909 6480464 sulforafan results in decreased phosphorylation of AKT1 protein CTD PMID:29407470 sulforaphane decreases phosphorylation EXP 6480464 sulforafan results in decreased phosphorylation of AKT1 protein CTD PMID:17942926 sulforaphane multiple interactions EXP 6480464 [dibenzoylmethane co-treated with sulforafan] results in decreased phosphorylation of AKT1 protein CTD PMID:17942926 sulindac multiple interactions ISO RGD:732909 6480464 [AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein]] which affects the susceptibility to Oxygen, AKT1 protein affects the reaction [Sulindac analog results in decreased expression of HIF1A protein] CTD PMID:18924134 sulindac multiple interactions ISO RGD:2081 6480464 [Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of AKT1 mRNA CTD PMID:20371263 sulindac decreases phosphorylation ISO RGD:732909 6480464 Sulindac analog results in decreased phosphorylation of AKT1 protein CTD PMID:18924134 sulindac sulfone affects phosphorylation EXP 6480464 sulindac sulfone affects the phosphorylation of AKT1 protein CTD PMID:15570007 sulindac sulfone multiple interactions ISO RGD:2081 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of AKT1 protein, [Celecoxib co-treated with sulindac sulfone] results in decreased expression of AKT1 protein modified form CTD PMID:17908994 T-2 Toxin decreases expression ISO RGD:2081 6480464 T-2 Toxin results in decreased expression of AKT1 mRNA CTD PMID:26141394 tamarixetin decreases phosphorylation EXP 6480464 tamarixetin results in decreased phosphorylation of AKT1 protein CTD PMID:12826665 tamoxifen multiple interactions ISO RGD:732909 6480464 AKT1 protein inhibits the reaction [Tamoxifen analog results in increased activity of CASP3 protein] more ... CTD PMID:14990993 more ... tamoxifen decreases phosphorylation ISO RGD:732909 6480464 Tamoxifen results in decreased phosphorylation of AKT1 protein CTD PMID:20549698 , PMID:23921149 tamoxifen multiple interactions EXP 6480464 Tamoxifen results in decreased phosphorylation of and results in decreased activity of AKT1 protein CTD PMID:19393235 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of AKT1 mRNA CTD PMID:17555576 tamoxifen increases activity ISO RGD:732909 6480464 [Tamoxifen results in increased activity of AKT1 protein] which results in increased activity of MYC protein more ... CTD PMID:20372086 tamoxifen increases phosphorylation ISO RGD:732909 6480464 Tamoxifen analog results in increased phosphorylation of AKT1 protein CTD PMID:19549922 tanespimycin multiple interactions ISO RGD:732909 6480464 arsenic trioxide promotes the reaction [tanespimycin results in decreased expression of AKT1 protein], tanespimycin promotes the reaction [arsenic trioxide results in decreased expression of AKT1 protein] CTD PMID:18566239 tanespimycin decreases expression ISO RGD:732909 6480464 tanespimycin results in decreased expression of AKT1 protein CTD PMID:16923571 more ... taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein] CTD PMID:30362509 taurine multiple interactions ISO RGD:732909 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein] CTD PMID:30362509 taurocholic acid multiple interactions ISO RGD:2081 6480464 Taurocholic Acid inhibits the reaction [Carbon Tetrachloride results in decreased phosphorylation of AKT1 protein], wortmannin inhibits the reaction [Taurocholic Acid inhibits the reaction [Carbon Tetrachloride results in decreased phosphorylation of AKT1 protein]] CTD PMID:12388182 taurolithocholic acid multiple interactions ISO RGD:2081 6480464 JTE 013 inhibits the reaction [Taurolithocholic Acid results in increased phosphorylation of AKT1 protein] more ... CTD PMID:31300867 taurolithocholic acid increases phosphorylation ISO RGD:2081 6480464 Taurolithocholic Acid results in increased phosphorylation of AKT1 protein CTD PMID:31300867 tauroursodeoxycholic acid multiple interactions ISO RGD:2081 6480464 tauroursodeoxycholic acid inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein], tauroursodeoxycholic acid results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:12721362 , PMID:25398788 temozolomide multiple interactions ISO RGD:732909 6480464 AKT1 protein inhibits the reaction [temozolomide results in increased phosphorylation of and results in decreased activity of CDC25C protein] more ... CTD PMID:15930307 Temsirolimus multiple interactions ISO RGD:732909 6480464 arsenic trioxide affects the reaction [temsirolimus results in increased phosphorylation of AKT1 protein] CTD PMID:24392034 Temsirolimus multiple interactions EXP 6480464 [perifosine co-treated with temsirolimus] results in decreased activity of AKT1 protein CTD PMID:21267448 Temsirolimus increases phosphorylation ISO RGD:732909 6480464 temsirolimus results in increased phosphorylation of AKT1 protein CTD PMID:24392034 terbutylazine multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [terbutylazine results in decreased expression of and results in decreased phosphorylation of AKT1 protein] more ... CTD PMID:27431321 Terfenadine multiple interactions ISO RGD:732909 6480464 11 more ... CTD PMID:19289568 Terfenadine decreases phosphorylation ISO RGD:732909 6480464 Terfenadine analog results in decreased phosphorylation of AKT1 protein CTD PMID:19289568 teriflunomide decreases phosphorylation ISO RGD:732909 6480464 A 771726 results in decreased phosphorylation of AKT1 protein CTD PMID:19174558 terpinolene decreases expression ISO RGD:732909 6480464 terpinolene results in decreased expression of AKT1 protein CTD PMID:22740904 tert-butyl hydroperoxide multiple interactions ISO RGD:732909 6480464 3, 4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of AKT1 protein] CTD PMID:29128606 tert-butyl hydroperoxide decreases phosphorylation ISO RGD:732909 6480464 tert-Butylhydroperoxide results in decreased phosphorylation of AKT1 protein CTD PMID:29128606 testosterone multiple interactions ISO RGD:732909 6480464 Flutamide inhibits the reaction [Testosterone inhibits the reaction [Phosphates results in decreased phosphorylation of AKT1 protein]], Testosterone inhibits the reaction [Phosphates results in decreased phosphorylation of AKT1 protein] CTD PMID:20048160 testosterone increases phosphorylation ISO RGD:2081 6480464 Testosterone results in increased phosphorylation of AKT1 protein CTD PMID:26437446 , PMID:26492952 testosterone multiple interactions ISO RGD:2081 6480464 [Estradiol co-treated with Testosterone] results in increased expression of AKT1 mRNA more ... CTD PMID:11375906 more ... testosterone increases activity ISO RGD:2081 6480464 Testosterone deficiency results in increased activity of AKT1 protein CTD PMID:20850791 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Testosterone deficiency results in decreased phosphorylation of AKT1 protein] CTD PMID:21045173 testosterone decreases phosphorylation EXP 6480464 Testosterone deficiency results in decreased phosphorylation of AKT1 protein, Testosterone results in decreased phosphorylation of AKT1 protein CTD PMID:20403060 , PMID:21045173 testosterone increases phosphorylation ISO RGD:732909 6480464 Testosterone results in increased phosphorylation of AKT1 protein CTD PMID:21632903 testosterone enanthate increases phosphorylation ISO RGD:732909 6480464 testosterone enanthate results in increased phosphorylation of AKT1 protein CTD PMID:17440010 Tetrachlorobisphenol A increases acetylation ISO RGD:2081 6480464 tetrachlorodian results in increased acetylation of AKT1 protein CTD PMID:31332466 tetrachloromethane multiple interactions ISO RGD:2081 6480464 AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Cyclic GMP] more ... CTD PMID:12388182 more ... tetrachloromethane increases phosphorylation EXP 6480464 Carbon Tetrachloride results in increased phosphorylation of AKT1 protein CTD PMID:27865854 tetrachloromethane multiple interactions EXP 6480464 obeticholic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of AKT1 protein] CTD PMID:27865854 tetrachloromethane increases phosphorylation ISO RGD:2081 6480464 Carbon Tetrachloride results in increased phosphorylation of AKT1 protein CTD PMID:18317400 more ... tetrachloromethane decreases phosphorylation ISO RGD:2081 6480464 Carbon Tetrachloride results in decreased phosphorylation of AKT1 protein CTD PMID:12388182 , PMID:12891555 thalidomide decreases phosphorylation ISO RGD:732909 6480464 Thalidomide analog results in decreased phosphorylation of AKT1 protein CTD PMID:15858615 thalidomide decreases activity ISO RGD:732909 6480464 Thalidomide results in decreased activity of AKT1 protein CTD PMID:15067094 thalidomide increases phosphorylation ISO RGD:732909 6480464 Thalidomide analog results in increased phosphorylation of AKT1 protein CTD PMID:15858615 thapsigargin multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein] more ... CTD PMID:15339911 , PMID:22378314 thapsigargin increases phosphorylation ISO RGD:2081 6480464 Thapsigargin results in increased phosphorylation of AKT1 protein CTD PMID:25398788 thapsigargin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein], Wortmannin inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein] CTD PMID:25398788 thapsigargin decreases phosphorylation ISO RGD:732909 6480464 Thapsigargin results in decreased phosphorylation of AKT1 protein CTD PMID:22378314 thapsigargin multiple interactions EXP 6480464 [Thapsigargin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein CTD PMID:24898257 thapsigargin decreases expression ISO RGD:2081 6480464 Thapsigargin results in decreased expression of AKT1 protein modified form CTD PMID:16338971 thapsigargin increases phosphorylation ISO RGD:732909 6480464 Thapsigargin results in increased phosphorylation of AKT1 protein CTD PMID:15339911 thiamine(1+) chloride multiple interactions ISO RGD:2081 6480464 Thiamine inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein] CTD PMID:31419397 thiamine(1+) chloride multiple interactions EXP 6480464 Thiamine inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein] CTD PMID:31419397 thimerosal decreases phosphorylation EXP 6480464 Thimerosal results in decreased phosphorylation of AKT1 protein CTD PMID:23145070 thimerosal multiple interactions EXP 6480464 Thimerosal promotes the reaction [wortmannin results in decreased phosphorylation of AKT1 protein], wortmannin promotes the reaction [Thimerosal results in decreased phosphorylation of AKT1 protein] CTD PMID:23145070 thioacetamide increases expression ISO RGD:2081 6480464 Thioacetamide results in increased expression of AKT1 mRNA CTD PMID:28181416 thioacetamide increases phosphorylation ISO RGD:2081 6480464 Thioacetamide results in increased phosphorylation of AKT1 protein CTD PMID:30138605 thioacetamide multiple interactions ISO RGD:2081 6480464 Berberine inhibits the reaction [Thioacetamide results in increased phosphorylation of AKT1 protein] CTD PMID:30138605 Thiorphan decreases phosphorylation ISO RGD:732909 6480464 Thiorphan results in decreased phosphorylation of AKT1 protein CTD PMID:16405511 Thiorphan multiple interactions ISO RGD:732909 6480464 [Thiorphan results in decreased activity of MME protein] which affects the activity of AKT1 protein CTD PMID:16405511 tipifarnib multiple interactions ISO RGD:732909 6480464 tipifarnib inhibits the reaction [CSF2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:22315502 titanium dioxide increases phosphorylation ISO RGD:732909 6480464 titanium dioxide results in increased phosphorylation of AKT1 protein CTD PMID:31068539 titanium dioxide decreases phosphorylation EXP 6480464 titanium dioxide results in decreased phosphorylation of AKT1 protein CTD PMID:31298478 titanium dioxide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [titanium dioxide results in decreased phosphorylation of AKT1 protein] CTD PMID:31298478 titanium dioxide multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [titanium dioxide results in increased phosphorylation of AKT1 protein], Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of AKT1 protein] CTD PMID:31068539 tofacitinib multiple interactions EXP 6480464 tofacitinib inhibits the reaction [IL2 protein results in increased phosphorylation of AKT1 protein] CTD PMID:21383241 toluene 2,4-diisocyanate multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Toluene 2, 4-Diisocyanate results in increased phosphorylation of AKT1 protein] CTD PMID:26089345 toluene 2,4-diisocyanate increases phosphorylation EXP 6480464 Toluene 2, 4-Diisocyanate results in increased phosphorylation of AKT1 protein CTD PMID:26089345 topiramate multiple interactions ISO RGD:2081 6480464 topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of AKT1 protein] CTD PMID:29753867 trametinib increases phosphorylation ISO RGD:732909 6480464 trametinib results in increased phosphorylation of AKT1 protein CTD PMID:22733540 trametinib multiple interactions ISO RGD:732909 6480464 [2, 4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide co-treated with trametinib] results in decreased phosphorylation of AKT1 protein CTD PMID:22733540 trans-anethole decreases phosphorylation ISO RGD:732909 6480464 anethole results in decreased phosphorylation of AKT1 protein CTD PMID:21212515 triamcinolone decreases phosphorylation ISO RGD:2081 6480464 Triamcinolone results in decreased phosphorylation of AKT1 protein CTD PMID:15187100 tributylstannane increases phosphorylation EXP 6480464 tributyltin results in increased phosphorylation of AKT1 protein CTD PMID:30172001 tributylstannane increases expression ISO RGD:2081 6480464 tributyltin results in increased expression of AKT1 protein CTD PMID:30172001 Tributyltin oxide decreases expression ISO RGD:2081 6480464 bis(tri-n-butyltin)oxide results in decreased expression of AKT1 mRNA CTD PMID:17553608 trichostatin A multiple interactions ISO RGD:732909 6480464 [perifosine co-treated with trichostatin A] results in decreased activity of AKT1 protein more ... CTD PMID:15781658 , PMID:26509796 triciribine decreases phosphorylation ISO RGD:732909 6480464 triciribine results in decreased phosphorylation of AKT1 protein CTD PMID:20857426 triclosan decreases phosphorylation EXP 6480464 Triclosan results in decreased phosphorylation of AKT1 protein CTD PMID:28973666 triclosan decreases phosphorylation ISO RGD:2081 6480464 Triclosan results in decreased phosphorylation of AKT1 protein CTD PMID:31381933 triclosan multiple interactions EXP 6480464 [rosiglitazone results in increased activity of PPARG protein] inhibits the reaction [Triclosan results in decreased phosphorylation of AKT1 protein] CTD PMID:28973666 trifluoperazine multiple interactions ISO RGD:2081 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein], Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19233221 , PMID:21544200 trifluoperazine multiple interactions EXP 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:21544200 triphenylstannane multiple interactions ISO RGD:2081 6480464 [triphenyltin co-treated with ethylene dimethanesulfonate] affects the phosphorylation of AKT1 protein CTD PMID:30772500 Triptolide multiple interactions ISO RGD:2081 6480464 triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein] CTD PMID:21717513 triptonide multiple interactions ISO RGD:732909 6480464 triptonide results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:28666825 tris(2-chloroethyl) phosphate multiple interactions ISO RGD:732909 6480464 tris(chloroethyl)phosphate results in decreased expression of and results in decreased phosphorylation of AKT1 protein CTD PMID:26378621 troglitazone multiple interactions ISO RGD:732909 6480464 [troglitazone co-treated with Aspirin] results in decreased expression of AKT1 protein, [troglitazone co-treated with Aspirin] results in decreased expression of AKT1 protein modified form CTD PMID:19908241 tunicamycin multiple interactions EXP 6480464 [Tunicamycin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein, HSPA5 protein affects the reaction [[Tunicamycin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein] CTD PMID:24898257 tunicamycin increases phosphorylation ISO RGD:2081 6480464 Tunicamycin results in increased phosphorylation of AKT1 protein CTD PMID:25398788 tunicamycin multiple interactions ISO RGD:732909 6480464 MT2A protein inhibits the reaction [Tunicamycin results in decreased phosphorylation of AKT1 protein] CTD PMID:24680926 tunicamycin decreases phosphorylation ISO RGD:2081 6480464 Tunicamycin results in decreased phosphorylation of AKT1 protein CTD PMID:24680926 tunicamycin multiple interactions ISO RGD:2081 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [MT2A protein inhibits the reaction [Tunicamycin results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:24680926 , PMID:25398788 tunicamycin decreases phosphorylation ISO RGD:732909 6480464 Tunicamycin results in decreased phosphorylation of AKT1 protein CTD PMID:22378314 Tylophorine multiple interactions ISO RGD:732909 6480464 tylophorine analog inhibits the reaction [TNF results in increased activity of AKT1 protein], tylophorine analog results in decreased phosphorylation of and results in decreased expression of AKT1 CTD PMID:19284764 tyrphostin AG 1478 multiple interactions ISO RGD:2081 6480464 RTKI cpd inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] more ... CTD PMID:15849355 more ... tyrphostin AG 1478 multiple interactions ISO RGD:732909 6480464 RTKI cpd inhibits the reaction [Cadmium Chloride results in increased cleavage of AKT1 protein] more ... CTD PMID:11309286 more ... U-73122 multiple interactions ISO RGD:732909 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:15177934 ursodeoxycholic acid multiple interactions ISO RGD:732909 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased phosphorylation of AKT1 protein] CTD PMID:19073151 ursodeoxycholic acid increases phosphorylation ISO RGD:732909 6480464 Ursodeoxycholic Acid results in increased phosphorylation of AKT1 protein CTD PMID:19073151 ursolic acid decreases phosphorylation ISO RGD:732909 6480464 ursolic acid results in decreased phosphorylation of AKT1 protein CTD PMID:19344998 , PMID:24802810 usnic acid multiple interactions ISO RGD:732909 6480464 usnic acid results in decreased phosphorylation of and results in decreased expression of AKT1 protein CTD PMID:25078063 valproic acid increases expressi 
Gene-Chemical Interaction Annotations