Aldh1a3 (aldehyde dehydrogenase family 1, subfamily A3) - Rat Genome Database

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Gene: Aldh1a3 (aldehyde dehydrogenase family 1, subfamily A3) Mus musculus
Analyze
Symbol: Aldh1a3
Name: aldehyde dehydrogenase family 1, subfamily A3
RGD ID: 733398
MGI Page MGI
Description: Enables NAD+ binding activity; aldehyde dehydrogenase (NAD+) activity; and thyroid hormone binding activity. Involved in Harderian gland development; embryonic camera-type eye development; and nose development. Acts upstream of or within several processes, including embryonic organ morphogenesis; nucleus accumbens development; and olfactory pit development. Located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in isolated microphthalmia 8. Orthologous to human ALDH1A3 (aldehyde dehydrogenase 1 family member A3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ALD; aldehyde dehydrogenase 6; aldehyde dehydrogenase family 1 member A3; aldehyde dehydrogenase-6; ALDH6; RAL; RALDH-3; RALDH3; retinaldehyde dehydrogenase 3; V; V1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39766,040,640 - 66,077,225 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl766,040,638 - 66,077,265 (-)EnsemblGRCm39 Ensembl
GRCm38766,390,892 - 66,427,477 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl766,390,890 - 66,427,517 (-)EnsemblGRCm38mm10GRCm38
MGSCv37773,535,778 - 73,572,363 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36766,269,842 - 66,313,378 (-)NCBIMGSCv36mm8
Celera763,845,586 - 63,882,073 (-)NCBICelera
Cytogenetic Map7CNCBI
cM Map735.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-dichloroaniline  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
adefovir pivoxil  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinal  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
butan-1-ol  (ISO)
butanal  (ISO)
butane-2,3-dione  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
carbon nanotube  (EXP,ISO)
carmustine  (ISO)
carnosic acid  (EXP)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
choline  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt dichloride  (ISO)
crotonaldehyde  (ISO)
cycloheximide  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (EXP,ISO)
diquat  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
Erionite  (EXP)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
fonofos  (ISO)
formaldehyde  (ISO)
furan  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
glycidyl methacrylate  (ISO)
glyphosate  (ISO)
graphite  (ISO)
hypochlorous acid  (ISO)
ifosfamide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
isoflavones  (ISO)
L-methionine  (EXP)
lithium atom  (ISO)
lithium chloride  (ISO)
lithium hydride  (ISO)
menadione  (EXP)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
monosodium L-glutamate  (EXP)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-nitrosodiethylamine  (ISO)
nitrofen  (ISO)
Nutlin-3  (ISO)
omeprazole  (ISO)
ozone  (EXP,ISO)
panobinostat  (ISO)
paraquat  (ISO)
parathion  (ISO)
pentanal  (ISO)
pentane-2,3-dione  (ISO)
phenylmercury acetate  (ISO)
PhIP  (ISO)
picene  (ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pravastatin  (EXP,ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
Tanshinone I  (ISO)
tebuconazole  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
thapsigargin  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
Yessotoxin  (ISO)
zaragozic acid A  (EXP,ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Immunolocalization of retinoic acid biosynthesis systems in selected sites in rat. Everts HB, etal., Exp Cell Res. 2005 Aug 15;308(2):309-19.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Physiological insights into all-trans-retinoic acid biosynthesis. Napoli JL Biochim Biophys Acta. 2012 Jan;1821(1):152-67. Epub 2011 May 19.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Toresson H and Campbell K, Development 2001 Dec;128(23):4769-80.
12. Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes. Wang C, etal., J Biol Chem. 2011 Feb 25;286(8):6542-53. Epub 2010 Dec 7.
Additional References at PubMed
PMID:10349636   PMID:10906479   PMID:11013254   PMID:11025231   PMID:11042159   PMID:11044606   PMID:11076861   PMID:11217851   PMID:11744377   PMID:11959834   PMID:12427676   PMID:12454286  
PMID:12477932   PMID:12808103   PMID:14623956   PMID:14681479   PMID:15161092   PMID:15245423   PMID:15269172   PMID:15489334   PMID:15531370   PMID:15766748   PMID:16026781   PMID:16141072  
PMID:16141073   PMID:16207763   PMID:16241904   PMID:16280085   PMID:16368932   PMID:16611695   PMID:16615129   PMID:16836633   PMID:16854970   PMID:16973151   PMID:17184764   PMID:17207476  
PMID:17270348   PMID:17880938   PMID:18287559   PMID:18331719   PMID:18393306   PMID:18399539   PMID:18443282   PMID:18561907   PMID:18832390   PMID:18971422   PMID:18985738   PMID:19386638  
PMID:19448158   PMID:19449303   PMID:19464179   PMID:19519663   PMID:19549509   PMID:19618468   PMID:19700620   PMID:19737349   PMID:19766701   PMID:19854269   PMID:20040494   PMID:20122913  
PMID:20236931   PMID:20503368   PMID:20735826   PMID:21148184   PMID:21224842   PMID:21267068   PMID:21309073   PMID:21436255   PMID:21532733   PMID:21539829   PMID:21565611   PMID:21677750  
PMID:21752936   PMID:21873635   PMID:21895658   PMID:21930923   PMID:21982646   PMID:22461561   PMID:22869719   PMID:22930583   PMID:23012458   PMID:23077214   PMID:23142317   PMID:23201021  
PMID:23484127   PMID:23536097   PMID:23696569   PMID:23720040   PMID:23806210   PMID:23829703   PMID:24005908   PMID:24161570   PMID:24194600   PMID:24699546   PMID:24780627   PMID:24952961  
PMID:25261715   PMID:25577283   PMID:25715397   PMID:25800090   PMID:26352270   PMID:26427057   PMID:26446231   PMID:26511239   PMID:26885858   PMID:27025388   PMID:27572106   PMID:27845622  
PMID:28245920   PMID:28250050   PMID:28274610   PMID:28715412   PMID:28790015   PMID:28864008   PMID:29093497   PMID:29467333   PMID:29609731   PMID:29986869   PMID:30166332   PMID:30487180  
PMID:30649340   PMID:30868103   PMID:30916783   PMID:31241463   PMID:31515492   PMID:31896743   PMID:31913463   PMID:32001436   PMID:32253237   PMID:32404350   PMID:32494737   PMID:32665247  
PMID:32798765   PMID:33201874   PMID:33428890   PMID:33564883   PMID:33764154   PMID:34003106   PMID:34321999   PMID:34599305   PMID:34623260   PMID:35020897   PMID:35156680   PMID:35175194  
PMID:35315776   PMID:35830795   PMID:35905011   PMID:36094016   PMID:36732513   PMID:37610090   PMID:37904003   PMID:38011284   PMID:38078651   PMID:38355793   PMID:38505613  


Genomics

Comparative Map Data
Aldh1a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39766,040,640 - 66,077,225 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl766,040,638 - 66,077,265 (-)EnsemblGRCm39 Ensembl
GRCm38766,390,892 - 66,427,477 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl766,390,890 - 66,427,517 (-)EnsemblGRCm38mm10GRCm38
MGSCv37773,535,778 - 73,572,363 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36766,269,842 - 66,313,378 (-)NCBIMGSCv36mm8
Celera763,845,586 - 63,882,073 (-)NCBICelera
Cytogenetic Map7CNCBI
cM Map735.73NCBI
ALDH1A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3815100,879,831 - 100,916,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl15100,877,714 - 100,916,626 (+)EnsemblGRCh38hg38GRCh38
GRCh3715101,420,036 - 101,456,831 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361599,237,532 - 99,274,354 (+)NCBINCBI36Build 36hg18NCBI36
Build 341599,237,583 - 99,274,352NCBI
Celera1577,832,935 - 77,870,170 (+)NCBICelera
Cytogenetic Map15q26.3NCBI
HuRef1577,542,416 - 77,578,726 (+)NCBIHuRef
CHM1_115101,260,984 - 101,297,814 (+)NCBICHM1_1
T2T-CHM13v2.01598,634,889 - 98,671,163 (+)NCBIT2T-CHM13v2.0
Aldh1a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81129,392,516 - 129,436,552 (-)NCBIGRCr8
mRatBN7.21119,982,272 - 120,017,416 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1119,982,277 - 120,017,436 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1127,975,926 - 128,009,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01135,147,379 - 135,180,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,957,727 - 127,991,000 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,302,920 - 127,337,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,301,128 - 127,337,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01128,382,914 - 128,415,160 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41120,847,746 - 120,881,883 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11120,926,088 - 120,960,226 (-)NCBI
Celera1112,188,129 - 112,221,404 (-)NCBICelera
Cytogenetic Map1q22NCBI
Aldh1a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541627,823,611 - 27,858,173 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541627,823,611 - 27,858,112 (+)NCBIChiLan1.0ChiLan1.0
ALDH1A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21690,469,977 - 90,506,962 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11594,170,122 - 94,207,128 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01579,603,893 - 79,640,866 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11598,891,776 - 98,928,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1598,891,770 - 98,928,396 (+)Ensemblpanpan1.1panPan2
ALDH1A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1340,130,904 - 40,168,686 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl340,132,726 - 40,168,664 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha342,820,112 - 42,857,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0340,522,454 - 40,560,130 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl340,522,340 - 40,560,113 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1340,054,895 - 40,092,579 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0340,292,280 - 40,329,945 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0340,494,117 - 40,531,822 (-)NCBIUU_Cfam_GSD_1.0
Aldh1a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640143,367,150 - 143,403,705 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364832,930,789 - 2,967,346 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364832,930,781 - 2,967,309 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDH1A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1139,451,049 - 139,491,511 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11139,451,080 - 139,491,514 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21155,732,334 - 155,751,055 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALDH1A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12919,347,101 - 19,383,600 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605927,159,145 - 27,196,034 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldh1a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247683,851,257 - 3,885,609 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247683,851,361 - 3,885,609 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aldh1a3
1275 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2060
Count of miRNA genes:794
Interacting mature miRNAs:1011
Transcripts:ENSMUST00000015278, ENSMUST00000173756, ENSMUST00000174209, ENSMUST00000174215, ENSMUST00000174701
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
13506761Tbthq1_mtrabecular bone thickness QTL 1 (mouse)76234974867749748Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
13432171Rosd1_mrotarod saline difference 1 (mouse)75919437869004862Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
12738423Lfibq6_mliver fibrosis QTL 6 (mouse)74769437866704862Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
13506750Tbthq2_mtrabecular bone thickness QTL 2 (mouse)76565974877549748Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
25314302Vmm2_mvariable multisystem mineralization 2, heart (mouse)74714974874149748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse

Markers in Region
20.MMHAP47FLG2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38766,393,684 - 66,393,758UniSTSGRCm38
MGSCv37773,538,570 - 73,538,644UniSTSGRCm37
Celera763,848,378 - 63,848,452UniSTS
Cytogenetic Map7CUniSTS
Whitehead_YAC7 UniSTS
Aldh1a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38766,391,284 - 66,392,222UniSTSGRCm38
MGSCv37773,536,170 - 73,537,108UniSTSGRCm37
Celera763,845,978 - 63,846,916UniSTS
Cytogenetic Map7CUniSTS
cM Map7 UniSTS
PMC283541P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38766,407,889 - 66,408,140UniSTSGRCm38
MGSCv37773,552,775 - 73,553,026UniSTSGRCm37
Celera763,862,587 - 63,862,838UniSTS
Cytogenetic Map7CUniSTS
Aldh1a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38766,427,314 - 66,427,431UniSTSGRCm38
MGSCv37773,572,200 - 73,572,317UniSTSGRCm37
Celera763,881,910 - 63,882,027UniSTS
Cytogenetic Map7CUniSTS
Aldh1a3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7CUniSTS


Expression


Sequence


Ensembl Acc Id: ENSMUST00000015278   ⟹   ENSMUSP00000015278
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl766,040,638 - 66,077,265 (-)Ensembl
GRCm38.p6 Ensembl766,390,890 - 66,427,517 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173756
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl766,049,643 - 66,055,750 (-)Ensembl
GRCm38.p6 Ensembl766,399,895 - 66,406,002 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174209   ⟹   ENSMUSP00000146806
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl766,058,259 - 66,076,337 (-)Ensembl
GRCm38.p6 Ensembl766,408,511 - 66,426,589 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174215   ⟹   ENSMUSP00000146703
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl766,058,705 - 66,075,449 (-)Ensembl
GRCm38.p6 Ensembl766,408,957 - 66,425,701 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174701   ⟹   ENSMUSP00000133370
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl766,051,797 - 66,068,983 (-)Ensembl
GRCm38.p6 Ensembl766,402,049 - 66,419,235 (-)Ensembl
RefSeq Acc Id: NM_053080   ⟹   NP_444310
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39766,040,640 - 66,077,225 (-)NCBI
GRCm38766,390,892 - 66,427,477 (-)ENTREZGENE
MGSCv37773,535,778 - 73,572,363 (-)RGD
Celera763,845,586 - 63,882,073 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_444310   ⟸   NM_053080
- UniProtKB: Q9EQP7 (UniProtKB/Swiss-Prot),   Q9JI72 (UniProtKB/Swiss-Prot),   Q9JHW9 (UniProtKB/Swiss-Prot),   Q3UIA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000015278   ⟸   ENSMUST00000015278
Ensembl Acc Id: ENSMUSP00000133370   ⟸   ENSMUST00000174701
Ensembl Acc Id: ENSMUSP00000146703   ⟸   ENSMUST00000174215
Ensembl Acc Id: ENSMUSP00000146806   ⟸   ENSMUST00000174209
Protein Domains
Aldehyde dehydrogenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHW9-F1-model_v2 AlphaFold Q9JHW9 1-512 view protein structure

Promoters
RGD ID:8664383
Promoter ID:EPDNEW_M10222
Type:multiple initiation site
Name:Aldh1a3_1
Description:Mus musculus aldehyde dehydrogenase family 1, subfamily A3 ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38766,427,477 - 66,427,537EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1861722 AgrOrtholog
Ensembl Genes ENSMUSG00000015134 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000015278 ENTREZGENE
  ENSMUST00000015278.15 UniProtKB/Swiss-Prot
  ENSMUST00000174209.8 UniProtKB/TrEMBL
  ENSMUST00000174215.2 UniProtKB/TrEMBL
  ENSMUST00000174701.2 UniProtKB/TrEMBL
InterPro Ald_DH/histidinol_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_CS_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ald_DH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldehyde_DH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldehyde_DH_NAD(P) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56847 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1861722 ENTREZGENE
NCBI Gene 56847 ENTREZGENE
PANTHER ALDEHYDE DEHYDROGENASE FAMILY 1 MEMBER A3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDEHYDE DEHYDROGENASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldedh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aldh1a3 PhenoGen
PIRSF ALDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ALDEHYDE_DEHYDR_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALDEHYDE_DEHYDR_GLU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140LIF9_MOUSE UniProtKB/TrEMBL
  AL1A3_MOUSE UniProtKB/Swiss-Prot
  G3UWP3_MOUSE UniProtKB/TrEMBL
  Q3UIA4 ENTREZGENE, UniProtKB/TrEMBL
  Q810V9_MOUSE UniProtKB/TrEMBL
  Q8R345_MOUSE UniProtKB/TrEMBL
  Q9EQP7 ENTREZGENE
  Q9JHW9 ENTREZGENE
  Q9JI72 ENTREZGENE
UniProt Secondary Q9EQP7 UniProtKB/Swiss-Prot
  Q9JI72 UniProtKB/Swiss-Prot