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Gene: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit) Mus musculus
Symbol: Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Description: Exhibits 3'-5' exonuclease activity and enzyme binding activity. Involved in DNA biosynthetic process; DNA replication proofreading; and base-excision repair, gap-filling. Localizes to delta DNA polymerase complex. Predicted to colocalize with nuclear chromosome, telomeric region. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human POLD1 (DNA polymerase delta 1, catalytic subunit); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; base excision repair pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 125kDa; 3'-5' exodeoxyribonuclease; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit
Homo sapiens (human) : POLD1 (DNA polymerase delta 1, catalytic subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pold1 (DNA polymerase delta 1, catalytic subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pold1 (DNA polymerase delta 1, catalytic subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLD1 (DNA polymerase delta 1, catalytic subunit)
Canis lupus familiaris (dog) : POLD1 (DNA polymerase delta 1, catalytic subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pold1 (DNA polymerase delta 1, catalytic subunit)
Sus scrofa (pig) : POLD1 (DNA polymerase delta 1, catalytic subunit)
Heterocephalus glaber (naked mole-rat) : Pold1 (DNA polymerase delta 1, catalytic subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl744,532,746 - 44,548,849 (-)EnsemblGRCm38mm10GRCm38
GRCm38744,532,744 - 44,548,815 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37751,788,114 - 51,804,185 (-)NCBIGRCm37mm9NCBIm37
MGSCv36744,400,791 - 44,416,858 (-)NCBImm8
Celera739,982,884 - 39,998,944 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pold1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734077
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.