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Gene: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit) Mus musculus
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Symbol: Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Description: Exhibits 3'-5' exonuclease activity and enzyme binding activity. Involved in DNA biosynthetic process; DNA replication proofreading; and base-excision repair, gap-filling. Localizes to delta DNA polymerase complex. Predicted to colocalize with nuclear chromosome, telomeric region. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human POLD1 (DNA polymerase delta 1, catalytic subunit); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; base excision repair pathway; INTERACTS WITH 1,2-dichloroethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 125kDa; 3'-5' exodeoxyribonuclease; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit
Orthologs:
Homo sapiens (human) : POLD1 (DNA polymerase delta 1, catalytic subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pold1 (DNA polymerase delta 1, catalytic subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pold1 (DNA polymerase delta 1, catalytic subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : POLD1 (DNA polymerase delta 1, catalytic subunit)
Canis lupus familiaris (dog) : POLD1 (DNA polymerase delta 1, catalytic subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pold1 (DNA polymerase delta 1, catalytic subunit)
Sus scrofa (pig) : POLD1 (DNA polymerase delta 1, catalytic subunit)
Heterocephalus glaber (naked mole-rat) : Pold1 (DNA polymerase delta 1, catalytic subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl744,532,746 - 44,548,849 (-)EnsemblGRCm38mm10GRCm38
GRCm38744,532,744 - 44,548,815 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37751,788,114 - 51,804,185 (-)NCBIGRCm37mm9NCBIm37
MGSCv36744,400,791 - 44,416,858 (-)NCBImm8
Celera739,982,884 - 39,998,944 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pold1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734077
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.