Slc40a1 (solute carrier family 40 (iron-regulated transporter), member 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Slc40a1 (solute carrier family 40 (iron-regulated transporter), member 1) Mus musculus
Analyze
Symbol: Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
RGD ID: 733073
MGI Page MGI
Description: Exhibits ferrous iron transmembrane transporter activity; identical protein binding activity; and peptide hormone binding activity. Involved in several processes, including iron ion export across plasma membrane; multicellular organismal iron ion homeostasis; and regulation of transcription by RNA polymerase II. Localizes to basolateral plasma membrane and synaptic vesicle. Is expressed in several structures, including central nervous system; extraembryonic component; genitourinary system; gut; and hemolymphoid system gland. Used to study hemochromatosis type 4. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1); PARTICIPATES IN iron efflux pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: duodenal-specific; Dus; Dusg; ferroportin 1; ferroportin-1; ferroportin1; FP; Fpn1; IRE; IREG1; iron-regulated transporter 1; metal transporter protein 1; metal transporting protein 1; MTP; MTP1; O; Ol5; Pc; Pcm; polycythaemia; Slc1; Slc11a3; SLC11A3 iron transporter; Slc39a1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 member 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39145,947,230 - 45,965,690 (-)NCBIGRCm39mm39
GRCm39 Ensembl145,947,228 - 45,965,683 (-)Ensembl
GRCm38145,908,070 - 45,926,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl145,908,068 - 45,926,523 (-)EnsemblGRCm38mm10GRCm38
MGSCv37145,964,915 - 45,982,439 (-)NCBIGRCm37mm9NCBIm37
MGSCv36145,852,630 - 45,870,079 (-)NCBImm8
Celera146,240,344 - 46,257,933 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-tert-butylhydroquinone  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-dihydroxybenzoate  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-tert-Octylphenol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
alcohol  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
apocynin  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
busulfan  (EXP)
buta-1,3-diene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cannabidiol  (EXP)
carbon nanotube  (EXP)
chloroprene  (EXP)
chlorpyrifos  (ISO)
chromium(6+)  (EXP,ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
cobalt atom  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cytarabine  (ISO)
desferrioxamine B  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
ethanol  (EXP)
ferric ammonium citrate  (EXP,ISO)
ferrostatin-1  (EXP)
flutamide  (ISO)
folic acid  (ISO)
gadolinium trichloride  (ISO)
Gastrodin  (EXP)
glycidol  (ISO)
hexane  (EXP)
hypochlorous acid  (EXP)
indometacin  (ISO)
iron atom  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP)
iron(III) nitrilotriacetate  (ISO)
isoprenaline  (EXP)
L-glutamic acid  (EXP)
lamivudine  (EXP)
lead diacetate  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
maneb  (EXP)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
mithramycin  (ISO)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nitric oxide  (ISO)
omeprazole  (EXP)
oxidopamine  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
p-tert-Amylphenol  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
pentachlorophenol  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenacetin  (ISO)
phenobarbital  (EXP)
phenylhydrazine  (ISO)
phenylmercury acetate  (ISO)
phorone  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
reactive oxygen species  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
succimer  (EXP)
sulforaphane  (EXP)
tamoxifen  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triptonide  (EXP)
tunicamycin  (EXP)
valproic acid  (EXP,ISO)
zidovudine  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal enzyme/coenzyme level  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal forebrain development  (IAGP)
abnormal iron homeostasis  (IAGP)
abnormal liver iron level  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver physiology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal pancreas morphology  (IAGP)
abnormal pancreatic acinar cell morphology  (IAGP)
abnormal spleen development  (IAGP)
abnormal spleen physiology  (IAGP)
anemia  (IAGP)
anisocytosis  (IAGP)
cachexia  (IAGP)
decreased body size  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased circulating iron level  (IAGP)
decreased circulating unsaturated transferrin level  (IAGP)
decreased embryo size  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased intestinal iron level  (IAGP)
decreased liver iron level  (IAGP)
decreased mean corpuscular hemoglobin  (IAGP)
decreased mean corpuscular volume  (IAGP)
decreased spleen iron level  (IAGP)
decreased thermal nociceptive threshold  (IEA)
edema  (IAGP)
embryonic lethality between implantation and somite formation, incomplete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IEA)
embryonic lethality prior to tooth bud stage  (IEA)
hemochromatosis  (IAGP)
hypochromic microcytic anemia  (IAGP)
increased brain iron level  (IAGP)
increased circulating ferritin level  (IAGP)
increased circulating iron level  (IAGP)
increased circulating lipase level  (IAGP)
increased circulating triglyceride level  (IEA)
increased circulating unsaturated transferrin level  (IAGP)
increased erythrocyte cell number  (IAGP)
increased heart iron level  (IAGP)
increased hematocrit  (IAGP)
increased hemoglobin content  (IAGP)
increased intestinal iron level  (IAGP)
increased kidney iron level  (IAGP)
increased liver iron level  (IAGP)
increased mean corpuscular volume  (IAGP)
increased pancreas iron level  (IAGP)
increased spleen iron level  (IAGP)
increased splenocyte apoptosis  (IAGP)
leptocytosis  (IAGP)
microphthalmia  (IAGP)
oxidative stress  (IAGP)
pallor  (IAGP)
poikilocytosis  (IAGP)
polycythemia  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
reticulocytosis  (IAGP)
small spleen  (IAGP)
References

Additional References at PubMed
PMID:7671812   PMID:9765983   PMID:10349636   PMID:10693807   PMID:10747949   PMID:10828623   PMID:10882071   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11175792   PMID:12161425  
PMID:12477932   PMID:12730111   PMID:12743117   PMID:12907459   PMID:14568251   PMID:14618243   PMID:14681479   PMID:14972659   PMID:14973193   PMID:14988440   PMID:15084469   PMID:15342464  
PMID:15469906   PMID:15489334   PMID:15514116   PMID:15665091   PMID:15667655   PMID:15764147   PMID:15888661   PMID:15932798   PMID:15933050   PMID:15935710   PMID:15956209   PMID:16054062  
PMID:16081696   PMID:16081760   PMID:16141072   PMID:16141073   PMID:16418170   PMID:16787915   PMID:17077321   PMID:17289807   PMID:17299088   PMID:17475779   PMID:17919498   PMID:18072938  
PMID:18159948   PMID:18369153   PMID:18586980   PMID:18653481   PMID:19141705   PMID:19234114   PMID:19252486   PMID:19252488   PMID:19416716   PMID:19596281   PMID:20015204   PMID:20065295  
PMID:20530874   PMID:20589901   PMID:20688958   PMID:20702562   PMID:20817278   PMID:21212186   PMID:21267068   PMID:21303654   PMID:21419768   PMID:21700773   PMID:21705499   PMID:21873635  
PMID:21907140   PMID:22492039   PMID:22921471   PMID:22992020   PMID:22996660   PMID:23064962   PMID:23375831   PMID:23395172   PMID:23630227   PMID:23656253   PMID:23837981   PMID:23846698  
PMID:24045836   PMID:24121729   PMID:24194600   PMID:24252754   PMID:24316081   PMID:24454764   PMID:24497831   PMID:24776745   PMID:24896847   PMID:24904115   PMID:24952961   PMID:25096756  
PMID:25100063   PMID:25662334   PMID:25713362   PMID:25758223   PMID:25782988   PMID:25824831   PMID:26301810   PMID:26506980   PMID:26693922   PMID:26929359   PMID:27465531   PMID:27483296  
PMID:27626380   PMID:27667162   PMID:28004654   PMID:28008752   PMID:28219768   PMID:28338217   PMID:28495746   PMID:28499927   PMID:29453656   PMID:29470856   PMID:29599243   PMID:29724825  
PMID:29923765   PMID:30073618   PMID:30115660   PMID:30213870   PMID:30352047   PMID:30776900   PMID:30888356   PMID:31011744   PMID:31152133   PMID:31166618   PMID:31416832   PMID:31761321  
PMID:32273468   PMID:32374849   PMID:32380257   PMID:32553114  


Genomics

Comparative Map Data
Slc40a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39145,947,230 - 45,965,690 (-)NCBIGRCm39mm39
GRCm39 Ensembl145,947,228 - 45,965,683 (-)Ensembl
GRCm38145,908,070 - 45,926,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl145,908,068 - 45,926,523 (-)EnsemblGRCm38mm10GRCm38
MGSCv37145,964,915 - 45,982,439 (-)NCBIGRCm37mm9NCBIm37
MGSCv36145,852,630 - 45,870,079 (-)NCBImm8
Celera146,240,344 - 46,257,933 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
SLC40A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2189,560,590 - 189,583,758 (-)EnsemblGRCh38hg38GRCh38
GRCh382189,560,590 - 189,580,811 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372190,425,316 - 190,445,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362190,133,561 - 190,153,858 (-)NCBINCBI36hg18NCBI36
Build 342190,250,823 - 190,271,119NCBI
Celera2184,020,234 - 184,040,455 (-)NCBI
Cytogenetic Map2q32.2NCBI
HuRef2182,284,805 - 182,305,032 (-)NCBIHuRef
CHM1_12190,431,102 - 190,451,326 (-)NCBICHM1_1
Slc40a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2948,033,526 - 48,053,876 (-)NCBI
Rnor_6.0 Ensembl952,894,365 - 52,912,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0952,819,451 - 52,830,461 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0952,560,116 - 52,579,079 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4944,977,430 - 44,995,358 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1944,979,984 - 44,996,778 (-)NCBI
Celera945,700,875 - 45,718,803 (-)NCBICelera
Cytogenetic Map9q22NCBI
Slc40a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554039,253,734 - 9,271,916 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554039,253,734 - 9,271,732 (+)NCBIChiLan1.0ChiLan1.0
SLC40A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B194,787,575 - 194,808,129 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B194,787,575 - 194,810,993 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B76,867,908 - 76,888,403 (-)NCBIMhudiblu_PPA_v0panPan3
SLC40A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.137308,054 - 329,037 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl37303,104 - 368,865 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha371,278,631 - 1,299,609 (-)NCBI
ROS_Cfam_1.037196,731 - 217,705 (-)NCBI
UMICH_Zoey_3.137209,278 - 230,249 (-)NCBI
UNSW_CanFamBas_1.037177,455 - 198,429 (-)NCBI
UU_Cfam_GSD_1.037205,666 - 226,640 (-)NCBI
Slc40a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303148,421,846 - 148,441,474 (-)NCBI
SpeTri2.0NW_0049365068,396,593 - 8,415,069 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC40A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1594,140,725 - 94,168,210 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11594,140,635 - 94,161,793 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215105,177,377 - 105,198,528 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC40A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11075,076,286 - 75,097,742 (-)NCBI
ChlSab1.1 Ensembl1075,075,971 - 75,096,271 (-)Ensembl
Vero_WHO_p1.0NW_023666040124,382,259 - 124,402,681 (+)NCBI
Slc40a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624899685,166 - 701,725 (+)NCBI

Position Markers
Slc40a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37145,968,198 - 45,968,291UniSTSGRCm37
Celera146,243,622 - 46,243,715UniSTS
Cytogenetic Map1BUniSTS
cM Map1 UniSTS
UniSTS:234123  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38145,908,577 - 45,908,821UniSTSGRCm38
MGSCv37145,965,422 - 45,965,666UniSTSGRCm37
Celera146,240,851 - 46,241,095UniSTS
Cytogenetic Map1BUniSTS
BB284629  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38145,908,477 - 45,908,600UniSTSGRCm38
MGSCv37145,965,322 - 45,965,445UniSTSGRCm37
Celera146,240,751 - 46,240,874UniSTS
Cytogenetic Map1BUniSTS
Whitehead/MRC_RH1750.63UniSTS
Slc40a1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38145,911,353 - 45,911,446UniSTSGRCm38
MGSCv37145,968,198 - 45,968,291UniSTSGRCm37
Celera146,243,622 - 46,243,715UniSTS
Cytogenetic Map1BUniSTS
cM Map1 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301240Sluc15_msusceptibility to lung cancer 15 (mouse)Not determined11902627053026373Mouse
1301073Orch5_mautoimmune orchitis resistance 5 (mouse)Not determined11902627053026373Mouse
1301756Pgia1_mproteoglycan induced arthritis 1 (mouse)Not determined11902627053026373Mouse
12880407V125Dq2_mvitamin D active form serum level QTL 2 (mouse)11930000053300000Mouse
1357475w3q13_mweight 3 weeks QTL 13 (mouse)Not determined12307051073937756Mouse
4142433Hbnr1_mHeligmosomoides bakeri nematode resistance 1 (mouse)Not determined2551111058234112Mouse
11100001Col4a1m1_mcollagen, type IV, alpha 1 modifier 1 (mouse)12551111062907723Mouse
12880409V125Dq1_mvitamin D active form serum level QTL 1 (mouse)12600000060000000Mouse
1357822Lvrq3_mliver weight QTL 3 (mouse)Not determined13472105773937756Mouse
1357759W3q12_mweight 3 weeks QTL 12 (mouse)Not determined13472105773937756Mouse
1357651Lgq5_mlate growth QTL 5 (mouse)Not determined13472105773937756Mouse
1357506W10q6_mweight 10 weeks QTL 6 (mouse)Not determined13472105773937756Mouse
1357524W6q14_mweight 6 weeks QTL 14 (mouse)Not determined13472105773937756Mouse
1357824Estoq4_membryo survival total QTL 4 (mouse)Not determined13472105773937756Mouse
39128207Lwq16_mliver weight QTL 16 (mouse)13472105773937756Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1301954Lrnx11_mlearning-contextual 11 (mouse)Not determined13909372774477206Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139093727126517573Mouse
12910780Pwgrq11_mpost-weaning growth rate QTL 11 (mouse)14082884867231097Mouse
12910786Pwgrq10_mpost-weaning growth rate QTL 10 (mouse)14082884867231097Mouse
12910788Pwgrq9_mpost-weaning growth rate QTL 9 (mouse)14082884867231097Mouse
1301166Thypr2_mthymocyte proliferative response 2 (mouse)Not determined14123396575234112Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14123624075236240Mouse
4141032Wbcc1_mwhite blood cell count 1 (mouse)Not determined4222050876220508Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14289887276899008Mouse
12050090Shm1_msperm head morphology 1 (mouse)14414774450777776Mouse
12879917Shm3_msperm head morphology 3 (mouse)14414774462907723Mouse
10412179Habiir1_mhyperoxic acute lung injury imprinted region 1 (mouse)Not determined14537861351924960Mouse
1558855Eae30_mexperimental allergic encephalomyelitis susceptibility 30 (mouse)Not determined14537861372935898Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
1301670Ssta1_msusceptibility to Salmonella typhimurium antigens 1 (mouse)Not determined14590759679907723Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:457
Count of miRNA genes:306
Interacting mature miRNAs:364
Transcripts:ENSMUST00000027137
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_016917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006496137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF215637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF216834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF226613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF231120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB625854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ207421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ207422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ207423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027137   ⟹   ENSMUSP00000027137
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,908,068 - 45,925,582 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186755
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,923,732 - 45,926,523 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186804   ⟹   ENSMUSP00000140969
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,921,217 - 45,926,519 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186822
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,918,936 - 45,925,262 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187406   ⟹   ENSMUSP00000140734
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,921,217 - 45,926,519 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187420   ⟹   ENSMUSP00000140549
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,921,217 - 45,926,519 (-)Ensembl
RefSeq Acc Id: ENSMUST00000188252
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,918,928 - 45,923,309 (-)Ensembl
RefSeq Acc Id: ENSMUST00000191247
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl145,915,241 - 45,925,609 (-)Ensembl
RefSeq Acc Id: NM_016917   ⟹   NP_058613
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39145,947,230 - 45,964,754 (-)NCBI
GRCm38145,908,070 - 45,925,594 (-)NCBI
MGSCv37145,964,915 - 45,982,439 (-)RGD
Celera146,240,344 - 46,257,933 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006496137   ⟹   XP_006496200
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39145,947,240 - 45,965,689 (-)NCBI
GRCm38145,908,080 - 45,926,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017321709   ⟹   XP_017177198
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39145,947,240 - 45,965,690 (-)NCBI
GRCm38145,908,080 - 45,926,532 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058613   ⟸   NM_016917
- UniProtKB: Q9JHI9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006496200   ⟸   XM_006496137
- Peptide Label: isoform X1
- UniProtKB: Q9JHI9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017177198   ⟸   XM_017321709
- Peptide Label: isoform X1
- UniProtKB: Q9JHI9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000027137   ⟸   ENSMUST00000027137
RefSeq Acc Id: ENSMUSP00000140969   ⟸   ENSMUST00000186804
RefSeq Acc Id: ENSMUSP00000140549   ⟸   ENSMUST00000187420
RefSeq Acc Id: ENSMUSP00000140734   ⟸   ENSMUST00000187406

Promoters
RGD ID:6873640
Promoter ID:EPDNEW_M271
Type:multiple initiation site
Name:Slc40a1_1
Description:Mus musculus solute carrier family 40 (iron-regulated transporter),member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M272  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38145,925,582 - 45,925,642EPDNEW
RGD ID:6873642
Promoter ID:EPDNEW_M272
Type:initiation region
Name:Slc40a1_2
Description:Mus musculus solute carrier family 40 (iron-regulated transporter),member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M271  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38145,926,526 - 45,926,586EPDNEW
RGD ID:6818482
Promoter ID:MM_KWN:642
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver
Transcripts:NM_016917,   UC007AWV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36145,982,166 - 45,982,666 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1315204 AgrOrtholog
Ensembl Genes ENSMUSG00000025993 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000027137 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000140549 UniProtKB/TrEMBL
  ENSMUSP00000140734 UniProtKB/TrEMBL
  ENSMUSP00000140969 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000027137 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000186804 UniProtKB/TrEMBL
  ENSMUST00000187406 UniProtKB/TrEMBL
  ENSMUST00000187420 UniProtKB/TrEMBL
InterPro Ferroportin-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:53945 UniProtKB/Swiss-Prot
MGD MGI:1315204 ENTREZGENE
NCBI Gene 53945 ENTREZGENE
PANTHER PTHR11660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FPN1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc40a1 PhenoGen
Superfamily-SCOP SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt C5H8V4_MOUSE UniProtKB/TrEMBL
  Q3TJ33_MOUSE UniProtKB/TrEMBL
  Q9JHI9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3UHZ9 UniProtKB/Swiss-Prot
  Q8BME5 UniProtKB/Swiss-Prot
  Q8BUM5 UniProtKB/Swiss-Prot
  Q9JIM9 UniProtKB/Swiss-Prot
  Q9JKP4 UniProtKB/Swiss-Prot