Prdx1 (peroxiredoxin 1) - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Prdx1 (peroxiredoxin 1) Mus musculus
Symbol: Prdx1
Name: peroxiredoxin 1
RGD ID: 733745
Description: Enables identical protein binding activity. Acts upstream of or within several processes, including natural killer cell mediated cytotoxicity; regulation of intracellular signal transduction; and removal of superoxide radicals. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; metanephros; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human PRDX1 (peroxiredoxin 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: macrophage 23 Kd stress protein; macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; MSP; MSP23; NkefA; OSF; OSF-3; OSF3; osteoblast specific factor 3; osteoblast-specific factor 3; P; PAG; Paga; peroxiredoxin-1; pr; PrdxI; proliferation-associated gene A; prx1; PrxI; Tdpx; Tdpx2; TDX2; thioredoxin dependent peroxide reductase 2; thioredoxin peroxidase 2; thioredoxin-dependent peroxide reductase 2; thioredoxin-dependent peroxiredoxin 1; TPxA; Trx dependent peroxide reductase 2
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm17915   Gm21399   Gm7204   Prdx1-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394116,542,796 - 116,557,197 (+)NCBIGRCm39mm39
GRCm39 Ensembl4116,542,741 - 116,558,019 (+)Ensembl
GRCm384116,685,599 - 116,700,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,685,544 - 116,700,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,358,204 - 116,372,605 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,183,531 - 116,197,932 (+)NCBImm8
Celera4115,419,593 - 115,433,994 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(S)-naringenin  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrabromodibenzodioxine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-tert-butylhydroquinone  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dihydrocoumarin  (EXP)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4-hydroxynon-2-enal  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP)
8-hydroxy-2'-deoxyguanosine  (EXP)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphibole asbestos  (ISO)
antimonite  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite ion  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
astaxanthin  (EXP)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
butyric acid  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
calycosin  (ISO)
capsaicin  (ISO)
captan  (EXP)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
chloramine T  (ISO)
chlordecone  (EXP)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
clobetasol  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
cumene hydroperoxide  (ISO)
Cuprizon  (ISO)
cylindrospermopsin  (EXP)
D-glucose  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP,ISO)
dicrotophos  (ISO)
diethyl maleate  (EXP,ISO)
dihydroartemisinin  (ISO)
dioscin  (EXP)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (EXP)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
ethoxyquin  (EXP)
etoposide  (EXP)
fenthion  (EXP)
finasteride  (ISO)
fipronil  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
frenolicin B  (ISO)
furan  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glucose  (ISO)
glutathione  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
herbicide  (EXP)
hexadecanoic acid  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
hypochlorous acid  (EXP)
indole-3-methanol  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP,ISO)
maneb  (ISO)
menadione  (EXP)
mercury dibromide  (ISO)
metam  (EXP)
methidathion  (EXP)
methimazole  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP,ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nickel atom  (ISO)
nimesulide  (ISO)
Nonylphenol  (ISO)
obeticholic acid  (ISO)
oleanolic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (EXP)
permethrin  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
phlorizin  (EXP)
picloram  (EXP)
picoxystrobin  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
procymidone  (ISO)
Propiverine  (ISO)
Pyridostigmine bromide  (ISO)
pyrogallol  (EXP)
quartz  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (EXP,ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
rottlerin  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
SB 203580  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (EXP)
staurosporine  (EXP)
streptozocin  (EXP,ISO)
styrene  (ISO)
sulfasalazine  (EXP,ISO)
sulforaphane  (ISO)
sulindac  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP)
titanium dioxide  (ISO)
Tomentosin  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (EXP)
trichlopyr  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenylstannane  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
tungsten  (EXP)
tunicamycin  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell cycle  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal lymphocyte morphology  (IEA)
abnormal NK T cell number  (IAGP)
abnormal redox activity  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal tumor morphology  (IAGP)
anisocytosis  (IAGP)
decreased cell proliferation  (IAGP)
decreased circulating haptoglobin level  (IAGP)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
hemolytic anemia  (IAGP)
impaired natural killer cell mediated cytotoxicity  (IAGP)
increased adenoma incidence  (IAGP)
increased B cell derived lymphoma incidence  (IAGP)
increased carcinoma incidence  (IAGP)
increased cellular sensitivity to hydrogen peroxide  (IAGP)
increased cellular sensitivity to oxidative stress  (IAGP)
increased circulating lactate dehydrogenase level  (IAGP)
increased fibrosarcoma incidence  (IAGP)
increased hemangiosarcoma incidence  (IAGP)
increased hemoglobin concentration distribution width  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased histiocytic sarcoma incidence  (IAGP)
increased keratinocyte apoptosis  (IAGP)
increased lung adenocarcinoma incidence  (IAGP)
increased lymphoma incidence  (IAGP)
increased malignant tumor incidence  (IAGP)
increased mammary adenocarcinoma incidence  (IAGP)
increased osteosarcoma incidence  (IAGP)
increased pancreatic islet cell adenoma incidence  (IAGP)
increased sarcoma incidence  (IAGP)
increased spleen weight  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased tumor incidence  (IAGP)
microcytosis  (IAGP)
poikilocytosis  (IAGP)
polychromatophilia  (IAGP)
premature death  (IAGP)
reticulocytosis  (IAGP)
thin skin  (IAGP)

References - curated
# Reference Title Reference Citation
1. Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. Pfisterer P, etal., J Biol Chem 2002 Feb 22;277(8):6637-44. Epub 2001 Dec 10.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8026862   PMID:8089076   PMID:8360158   PMID:8889548   PMID:9507200   PMID:10349636   PMID:10501973   PMID:10548725   PMID:10632718   PMID:10725249   PMID:10922068   PMID:11042159  
PMID:11076861   PMID:11796722   PMID:12107731   PMID:12196529   PMID:12477932   PMID:12519079   PMID:12520002   PMID:12627171   PMID:12714748   PMID:12891360   PMID:12904583   PMID:12960165  
PMID:14610273   PMID:14681479   PMID:15161859   PMID:15237445   PMID:15448164   PMID:15489334   PMID:15741177   PMID:15782199   PMID:15858817   PMID:16141072   PMID:16141073   PMID:16170382  
PMID:16278420   PMID:16297875   PMID:16880205   PMID:16888816   PMID:17408621   PMID:17609286   PMID:17634366   PMID:17640558   PMID:17697936   PMID:17921138   PMID:18070609   PMID:18544346  
PMID:18614015   PMID:18689572   PMID:18799693   PMID:19098005   PMID:19369943   PMID:19521566   PMID:19647805   PMID:19766572   PMID:19941984   PMID:20018613   PMID:20178744   PMID:20683885  
PMID:20697350   PMID:21239607   PMID:21319188   PMID:21434354   PMID:21516123   PMID:21565611   PMID:21677750   PMID:21873635   PMID:22099303   PMID:22496890   PMID:22794259   PMID:23019345  
PMID:23101509   PMID:23185615   PMID:23186333   PMID:23237955   PMID:23375831   PMID:23479738   PMID:23487789   PMID:23602274   PMID:23665500   PMID:24295341   PMID:24457600   PMID:24715692  
PMID:25975898   PMID:26336360   PMID:26370502   PMID:26496610   PMID:27434733   PMID:27507650   PMID:27517622   PMID:27605010   PMID:27689697   PMID:27752147   PMID:27786251   PMID:27821296  
PMID:27926878   PMID:28378742   PMID:28485790   PMID:28605287   PMID:28659575   PMID:28671696   PMID:28893373   PMID:29032183   PMID:29048427   PMID:29215052   PMID:29382714   PMID:29503398  
PMID:29582423   PMID:29901182   PMID:30032718   PMID:30097850   PMID:30111318   PMID:30185517   PMID:30333137   PMID:30550785   PMID:30562941   PMID:30595499   PMID:30696882   PMID:30713523  
PMID:30894323   PMID:30991142   PMID:31026770   PMID:31028193   PMID:31257950   PMID:31419957   PMID:31526567   PMID:32325033   PMID:32423810   PMID:32531679   PMID:32682987   PMID:32705184  
PMID:32736685   PMID:33254076   PMID:33813037   PMID:34076143   PMID:34133714   PMID:34322898   PMID:34853030   PMID:35338481   PMID:35441400   PMID:35688114  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm394116,542,796 - 116,557,197 (+)NCBIGRCm39mm39
GRCm39 Ensembl4116,542,741 - 116,558,019 (+)Ensembl
GRCm384116,685,599 - 116,700,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,685,544 - 116,700,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv374116,358,204 - 116,372,605 (+)NCBIGRCm37mm9NCBIm37
MGSCv364116,183,531 - 116,197,932 (+)NCBImm8
Celera4115,419,593 - 115,433,994 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.28NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38145,511,051 - 45,522,890 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl145,510,914 - 45,542,732 (-)EnsemblGRCh38hg38GRCh38
GRCh37145,976,723 - 45,988,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,749,294 - 45,760,196 (-)NCBINCBI36hg18NCBI36
Build 34145,645,800 - 45,656,702NCBI
Celera144,260,797 - 44,271,582 (-)NCBI
Cytogenetic Map1p34.1NCBI
HuRef144,088,373 - 44,099,940 (-)NCBIHuRef
CHM1_1146,093,972 - 46,105,688 (-)NCBICHM1_1
T2T-CHM13v2.0145,383,419 - 45,395,258 (-)NCBI
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.25130,147,276 - 130,162,850 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl5130,147,204 - 130,162,856 (+)Ensembl
Rnor_6.05135,536,413 - 135,551,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,536,413 - 135,551,990 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,332,556 - 139,348,210 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,975,780 - 136,991,630 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15136,981,005 - 136,996,856 (+)NCBI
Celera5128,674,439 - 128,690,018 (+)NCBICelera
Cytogenetic Map5q35NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495546412,761,401 - 12,773,146 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546412,761,390 - 12,773,413 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
PanPan1.1146,171,453 - 46,182,018 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,171,453 - 46,182,018 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0144,813,508 - 44,824,430 (-)NCBIMhudiblu_PPA_v0panPan3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.11514,834,009 - 14,855,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,838,652 - 14,862,971 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,959,792 - 14,976,803 (+)NCBI
ROS_Cfam_1.01514,988,879 - 15,010,844 (+)NCBI
ROS_Cfam_1.0 Ensembl1514,993,508 - 15,018,355 (+)Ensembl
UMICH_Zoey_3.11514,790,828 - 14,808,277 (+)NCBI
UNSW_CanFamBas_1.01514,858,579 - 14,875,829 (+)NCBI
UU_Cfam_GSD_1.01514,930,831 - 14,947,857 (+)NCBI
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440505860,816,994 - 60,828,561 (-)NCBI
SpeTri2.0NW_00493647426,641,776 - 26,653,291 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl6165,824,395 - 165,861,442 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16165,847,390 - 165,859,918 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26153,253,841 - 153,265,947 (+)NCBISscrofa10.2Sscrofa10.2susScr3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.12087,267,026 - 87,277,634 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2087,267,044 - 87,279,978 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603329,683,931 - 29,694,719 (-)NCBIVero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_0046249061,405,253 - 1,414,926 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046249061,405,253 - 1,414,980 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381648,218,836 - 48,219,300UniSTSGRCm38
GRCm388129,253,229 - 129,253,700UniSTSGRCm38
MGSCv371648,218,949 - 48,219,413UniSTSGRCm37
Celera8133,554,923 - 133,555,394UniSTS
Celera1648,579,770 - 48,580,234UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map16B5UniSTS
cM Map447.0UniSTS
cM Map447.0UniSTS
cM Map749.0UniSTS
cM Map832.0UniSTS
cM Map866.0UniSTS
cM Map1636.0UniSTS
cM Map1748.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384116,684,984 - 116,685,250UniSTSGRCm38
MGSCv374116,357,589 - 116,357,855UniSTSGRCm37
Celera4115,418,978 - 115,419,244UniSTS
Cytogenetic Map4D1UniSTS
cM Map447.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384116,699,288 - 116,699,440UniSTSGRCm38
GRCm388129,253,629 - 129,253,781UniSTSGRCm38
MGSCv374116,371,893 - 116,372,045UniSTSGRCm37
Celera4115,433,282 - 115,433,434UniSTS
Celera8133,555,323 - 133,555,475UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map4D1UniSTS
cM Map447.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm388129,253,763 - 129,254,303UniSTSGRCm38
GRCm384116,699,423 - 116,699,963UniSTSGRCm38
MGSCv374116,372,028 - 116,372,568UniSTSGRCm37
Celera8133,555,457 - 133,555,997UniSTS
Celera4115,433,417 - 115,433,957UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map4D1UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381648,218,605 - 48,219,204UniSTSGRCm38
GRCm388129,252,998 - 129,253,597UniSTSGRCm38
MGSCv371648,218,718 - 48,219,317UniSTSGRCm37
Celera8133,554,692 - 133,555,291UniSTS
Celera1648,579,539 - 48,580,138UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map16B5UniSTS
Cytogenetic Map8E2UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map16B5UniSTS
cM Map1636.0UniSTS
cM Map749.0UniSTS
cM Map832.0UniSTS
cM Map1748.0UniSTS
cM Map447.0UniSTS
cM Map866.0UniSTS

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483604870117605006Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485428838119429037Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485781167119781279Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485781167119781279Mouse
27226716Metcl2_mmetatarsal-calcaneal length 2, 5 week (mouse)488118237118557197Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13824982Svwq1_mseminal vesicle weight QTL 1 (mouse)489888237118857197Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
13208565Bmiq6_mbody mass index QTL 6 (mouse)4110857197125893793Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301996Mmtg2_mmodifier of mammary tumor growth 2 (mouse)Not determined4116270979124055180Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1528
Count of miRNA genes:680
Interacting mature miRNAs:847
Transcripts:ENSMUST00000030454, ENSMUST00000106470, ENSMUST00000129315, ENSMUST00000135573, ENSMUST00000151129, ENSMUST00000156145
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.



Nucleotide Sequences
RefSeq Transcripts NM_011034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB023564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH008006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK002287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL831786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D16142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D21252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000030454   ⟹   ENSMUSP00000030454
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,544,509 - 116,556,383 (+)Ensembl
GRCm38.p6 Ensembl4116,687,312 - 116,699,186 (+)Ensembl
RefSeq Acc Id: ENSMUST00000106470   ⟹   ENSMUSP00000102078
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,543,084 - 116,556,469 (+)Ensembl
GRCm38.p6 Ensembl4116,685,887 - 116,699,272 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129315   ⟹   ENSMUSP00000117007
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,543,058 - 116,550,189 (+)Ensembl
GRCm38.p6 Ensembl4116,685,861 - 116,692,992 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135573   ⟹   ENSMUSP00000114159
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,542,741 - 116,558,019 (+)Ensembl
GRCm38.p6 Ensembl4116,685,544 - 116,700,822 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151129   ⟹   ENSMUSP00000119794
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,542,796 - 116,551,039 (+)Ensembl
GRCm38.p6 Ensembl4116,685,599 - 116,693,842 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156145
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4116,542,796 - 116,545,094 (+)Ensembl
GRCm38.p6 Ensembl4116,685,599 - 116,687,897 (+)Ensembl
RefSeq Acc Id: NM_011034   ⟹   NP_035164
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm394116,542,796 - 116,557,197 (+)NCBI
GRCm384116,685,599 - 116,700,000 (+)ENTREZGENE
MGSCv374116,358,204 - 116,372,605 (+)RGD
Celera4115,419,593 - 115,433,994 (+)RGD
Reference Sequences
RefSeq Acc Id: NP_035164   ⟸   NM_011034
- UniProtKB: P35700 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000102078   ⟸   ENSMUST00000106470
RefSeq Acc Id: ENSMUSP00000119794   ⟸   ENSMUST00000151129
RefSeq Acc Id: ENSMUSP00000114159   ⟸   ENSMUST00000135573
RefSeq Acc Id: ENSMUSP00000117007   ⟸   ENSMUST00000129315
RefSeq Acc Id: ENSMUSP00000030454   ⟸   ENSMUST00000030454
Protein Domains

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35700-F1-model_v2 AlphaFold P35700 1-199 view protein structure

RGD ID:6835909
Promoter ID:MM_KWN:39177
SO ACC ID:SO:0000170
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000106470,   OTTMUST00000021822,   OTTMUST00000021823,   OTTMUST00000021825,   OTTMUST00000021826
Mouse AssemblyChrPosition (strand)Source
MGSCv364116,358,029 - 116,358,529 (+)MPROMDB
RGD ID:6835908
Promoter ID:MM_KWN:39179
SO ACC ID:SO:0000170
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day4,   BoneMarrow_0Hour,   MEF_B6
Mouse AssemblyChrPosition (strand)Source
MGSCv364116,359,096 - 116,360,182 (+)MPROMDB
RGD ID:6884322
Promoter ID:EPDNEW_M5612
Type:initiation region
Description:Mus musculus peroxiredoxin 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm384116,685,599 - 116,685,659EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99523 AgrOrtholog
Ensembl Genes ENSMUSG00000028691 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000030454.6 UniProtKB/TrEMBL
  ENSMUSP00000102078 UniProtKB/Swiss-Prot
  ENSMUSP00000114159 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117007.2 UniProtKB/TrEMBL
  ENSMUSP00000119794.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030454.6 UniProtKB/TrEMBL
  ENSMUST00000106470 UniProtKB/Swiss-Prot
  ENSMUST00000129315.8 UniProtKB/TrEMBL
  ENSMUST00000135573 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000151129.8 UniProtKB/TrEMBL
InterPro AhpC/TSA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peroxiredoxin_AhpC-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peroxiredoxin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18477 UniProtKB/Swiss-Prot
Pfam 1-cysPrx_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AhpC-TSA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prdx1 PhenoGen
PIRSF AHPC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P35700 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3UBV4 UniProtKB/Swiss-Prot
  Q9CWI2 UniProtKB/Swiss-Prot