fipronil - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	fipronil	go back to main search page
Accession:	CHEBI:5063	browse the term
Definition:	A racemate comprising equimolar amounts of (R)- and (S)-fipronil.
Synonyms:	exact_synonym:	rac-5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile
	related_synonym:	(+-)-5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile; 5-amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-[(trifluoromethyl)sulfinyl]pyrazole-3-carbonitrile; rac-fipronil
	xref:	CAS:120068-37-3; KEGG:C11099; KEGG:D01042
	xref_mesh:	MESH:C082360
	xref:	PMID:14667049; PMID:17562454; PMID:17687584; PMID:18155147; PMID:18835630; PMID:19215184; PMID:19355792; PMID:20821427; PMID:22502899; PMID:23109279; PMID:23576335; PMID:23618775; PMID:24742550; PMID:24899256; PMID:24938819; PMID:25077813; PMID:25096486; PMID:25131894; Patent:EP295117; Patent:US5232940; Pesticides:fipronil; Reaxys:8090115; Wikipedia:Fipronil

show annotations for term's descendants Sort by:
Rat (1161) Mouse (1163) Human (1437) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (1161)

fipronil

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 1700009N14 gene like

decreases expression

fipronil results in decreased expression of 1700009N14RIKL mRNA

NCBI chr 5:54,456,005...54,457,381
Ensembl chr 5:54,455,893...54,457,677

G

AP2 associated kinase 1

decreases expression

fipronil results in decreased expression of AAK1 mRNA

NCBI chr 4:119,300,128...119,451,834
Ensembl chr 4:119,295,257...119,450,969

G

apoptosis antagonizing transcription factor

increases expression

fipronil results in increased expression of AATF mRNA

NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201

G

ATP binding cassette subfamily B member 1A

increases expression

fipronil results in increased expression of ABCB1A mRNA

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP-binding cassette, sub-family B member 1B

increases expression

fipronil results in increased expression of ABCB1B mRNA

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily C member 2

increases expression

fipronil results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression
multiple interactions

fipronil results in increased expression of ABCC3 mRNA
NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of ABCC3 mRNA]

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

increases expression

fipronil results in increased expression of ABCC4 mRNA

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily G member 5

increases expression

fipronil results in increased expression of ABCG5 mRNA

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

ATP binding cassette subfamily G member 8

increases expression

fipronil results in increased expression of ABCG8 mRNA

NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912

G

acetyl-CoA carboxylase alpha

multiple interactions
increases expression
decreases expression

AICA ribonucleotide inhibits the reaction [fipronil results in increased expression of and results in decreased phosphorylation of ACACA protein]; fipronil results in increased expression of and results in decreased phosphorylation of ACACA protein
fipronil results in increased expression of ACACA mRNA
fipronil results in decreased expression of ACACA mRNA

PMID:27103584 PMID:38050659

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acetyl-CoA carboxylase beta

affects expression

fipronil affects the expression of ACACB mRNA

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

alkaline ceramidase 2

increases expression

fipronil results in increased expression of ACER2 mRNA

NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614

G

acid phosphatase 1

increases expression

fipronil results in increased expression of ACP1 mRNA

NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021

G

acid phosphatase 2, lysosomal

increases expression

fipronil results in increased expression of ACP2 mRNA

NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680

G

actin, beta

increases expression

fipronil results in increased expression of ACTB mRNA

PMID:31881178 PMID:34044035

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin gamma 2, smooth muscle

increases expression

fipronil results in increased expression of ACTG2 mRNA

NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465

G

actin related protein 1B

decreases expression

fipronil results in decreased expression of ACTR1B mRNA

NCBI chr 9:38,928,819...38,938,483
Ensembl chr 9:38,929,912...38,938,507

G

adenosine deaminase

increases expression

fipronil results in increased expression of ADA mRNA

NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase domain 1a

decreases expression
multiple interactions

fipronil results in decreased expression of ADAM1A mRNA
[fipronil co-treated with DEET] results in decreased expression of ADAM1A mRNA

NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

decreases expression

fipronil results in decreased expression of ADAMTS1 mRNA

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

ADAMTS-like 2

increases expression

fipronil results in increased expression of ADAMTSL2 mRNA

NCBI chr 3:10,397,774...10,434,557
Ensembl chr 3:10,404,626...10,434,554

G

adhesion G protein-coupled receptor F5

increases expression

fipronil results in increased expression of ADGRF5 mRNA

NCBI chr 9:17,517,596...17,624,107
Ensembl chr 9:17,520,009...17,623,968

G

adhesion G protein-coupled receptor G1

increases expression

fipronil results in increased expression of ADGRG1 mRNA

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

alcohol dehydrogenase 4 (class II), pi polypeptide

increases expression

fipronil results in increased expression of ADH4 mRNA

NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591

G

adrenoceptor alpha 1A

decreases expression
multiple interactions

fipronil results in decreased expression of ADRA1A mRNA
[fipronil co-treated with DEET] results in decreased expression of ADRA1A mRNA

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

G

adrenoceptor alpha 1B

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of ADRA1B mRNA

NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919

G

adrenoceptor alpha 2A

increases expression

fipronil results in increased expression of ADRA2A mRNA

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

G

adrenoceptor alpha 2C

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of ADRA2C mRNA
fipronil results in increased expression of ADRA2C mRNA

NCBI chr14:75,470,884...75,472,846
Ensembl chr14:75,471,143...75,472,846

G

adrenoceptor beta 1

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of ADRB1 mRNA
fipronil results in increased expression of ADRB1 mRNA

NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259

G

adrenoceptor beta 2

increases expression
multiple interactions

fipronil results in increased expression of ADRB2 mRNA
[fipronil co-treated with DEET] results in increased expression of ADRB2 mRNA

NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512

G

apoptosis enhancing nuclease

decreases expression

fipronil results in decreased expression of AEN mRNA

NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523

G

AFG2 AAA ATPase homolog A

decreases expression

fipronil results in decreased expression of AFG2A mRNA

NCBI chr 2:120,306,417...120,497,707
Ensembl chr 2:120,306,412...120,497,705

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

increases expression

fipronil results in increased expression of AGAP2 mRNA

NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295

G

argonaute RISC catalytic component 2

increases expression

fipronil results in increased expression of AGO2 mRNA

NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974

G

alkylglycerone phosphate synthase

increases expression

fipronil results in increased expression of AGPS mRNA

NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830

G

ATP/GTP binding carboxypeptidase 1

increases expression

fipronil results in increased expression of AGTPBP1 mRNA

NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869

G

alanine--glyoxylate aminotransferase

decreases expression

fipronil results in decreased expression of AGXT mRNA

NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336

G

AT hook, DNA binding motif, containing 1

increases expression

fipronil results in increased expression of AHDC1 mRNA

NCBI chr 5:145,228,228...145,294,170
Ensembl chr 5:145,228,227...145,294,145

G

Abelson helper integration site 1

increases expression

fipronil results in increased expression of AHI1 mRNA

NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041

G

aryl hydrocarbon receptor

affects expression

fipronil affects the expression of AHR mRNA

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

activator of Hsp90 ATPase activity 1

decreases expression

fipronil results in decreased expression of AHSA1 mRNA

NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345

G

axin interactor, dorsalization associated

decreases expression

fipronil results in decreased expression of AIDA mRNA

NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

decreases expression

fipronil results in decreased expression of AIMP2 mRNA

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

A-kinase anchoring protein 13

decreases expression

fipronil results in decreased expression of AKAP13 mRNA

NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646

G

aldo-keto reductase family 1 member B1

increases expression

fipronil results in increased expression of AKR1B1 mRNA

NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157

G

aldo-keto reductase family 1, member C12-like 1

increases expression

fipronil results in increased expression of AKR1C12L1 mRNA

NCBI chr17:65,937,834...65,948,344
Ensembl chr17:65,937,814...65,997,595

G

aldo-keto reductase family 1, member C15

decreases expression
multiple interactions

fipronil results in decreased expression of AKR1C8 mRNA
[fipronil co-treated with DEET] results in decreased expression of AKR1C8 mRNA

NCBI chr17:66,181,493...66,208,090
Ensembl chr17:66,181,493...66,208,061

G

aldo-keto reductase family 1 member C3-like 1

increases expression

fipronil results in increased expression of AKR1C3L1 mRNA

NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488

G

aldo-keto reductase family 1, member E2

increases expression

fipronil results in increased expression of AKR1E2 mRNA

NCBI chr17:65,735,909...65,750,441
Ensembl chr17:65,735,943...65,750,441

G

aldo-keto reductase family 7 member A3

increases expression

fipronil results in increased expression of AKR7A3 mRNA

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

albumin

decreases expression
multiple interactions

fipronil results in decreased expression of ALB protein
Plant Extracts inhibits the reaction [fipronil results in decreased expression of ALB protein]

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 1 family, member A1

increases expression

fipronil results in increased expression of ALDH1A1 mRNA

PMID:23962444 PMID:31881178

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member B1

decreases expression

fipronil results in decreased expression of ALDH1B1 mRNA

NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378

G

aldehyde dehydrogenase 7 family, member A1

increases expression

fipronil results in increased expression of ALDH7A1 mRNA

NCBI chr18:50,003,242...50,042,193
Ensembl chr18:50,009,934...50,042,193

G

alkaline phosphatase, intestinal

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of ALPI mRNA
fipronil results in increased expression of ALPI mRNA

NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877

G

alkaline phosphatase, biomineralization associated

multiple interactions

fipronil inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA]

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

adenosylmethionine decarboxylase 1

decreases expression

fipronil results in decreased expression of AMD1 mRNA

NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476

G

antagonist of mitotic exit network 1 homolog

increases expression

fipronil results in increased expression of AMN1 mRNA

NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016

G

archaelysin family metallopeptidase 2

increases expression

fipronil results in increased expression of AMZ2 mRNA

NCBI chr10:94,401,546...94,412,116
Ensembl chr10:94,401,579...94,412,114

G

angiopoietin-like 2

decreases expression

fipronil results in decreased expression of ANGPTL2 mRNA

NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178

G

angiopoietin-like 3

increases expression

fipronil results in increased expression of ANGPTL3 mRNA

NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957

G

anoctamin 10

increases expression

fipronil results in increased expression of ANO10 mRNA

NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670

G

aldehyde oxidase 1

increases expression

fipronil results in increased expression of AOX1 mRNA

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

adaptor related protein complex 1 subunit gamma 2

decreases expression

fipronil results in decreased expression of AP1G2 mRNA

NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004

G

adaptor related protein complex 1 subunit sigma 3

decreases expression

fipronil results in decreased expression of AP1S3 mRNA

NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798

G

adaptor related protein complex 2 subunit alpha 2

decreases expression

fipronil results in decreased expression of AP2A2 mRNA

NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603

G

adaptor related protein complex 2 subunit mu 1

increases expression

fipronil results in increased expression of AP2M1 mRNA

NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140

G

adaptor related protein complex 3 subunit delta 1

increases expression

fipronil results in increased expression of AP3D1 mRNA

NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643

G

amyloid beta precursor protein binding family A member 3

increases expression

fipronil results in increased expression of APBA3 mRNA

NCBI chr 7:8,446,212...8,451,310
Ensembl chr 7:8,446,216...8,451,241

G

adipocyte plasma membrane associated protein

decreases expression

fipronil results in decreased expression of APMAP mRNA

NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341

G

apolipoprotein B mRNA editing enzyme catalytic subunit 3

decreases expression

fipronil results in decreased expression of APOBEC3 mRNA

NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922

G

amyloid beta precursor protein

increases expression

fipronil results in increased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 9

decreases expression

fipronil results in decreased expression of AQP9 mRNA

PMID:23962444 PMID:34044035

NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395

G

androgen receptor

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of AR mRNA; fipronil inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]

PMID:27091632 PMID:28728110

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

amphiregulin

increases expression

fipronil results in increased expression of AREG mRNA

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

apoptosis resistant E3 ubiquitin protein ligase 1

decreases expression

fipronil results in decreased expression of AREL1 mRNA

NCBI chr 6:104,560,556...104,617,712
Ensembl chr 6:104,564,986...104,617,628

G

ARF GTPase 4

decreases expression

fipronil results in decreased expression of ARF4 mRNA

NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261

G

arginase 1

decreases expression

fipronil results in decreased expression of ARG1 mRNA

PMID:32194361 PMID:34044035

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho GDP dissociation inhibitor alpha

decreases expression

fipronil results in decreased expression of ARHGDIA mRNA

NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023

G

Rho guanine nucleotide exchange factor 19

decreases expression

fipronil results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203

G

Rho guanine nucleotide exchange factor 28

increases expression

fipronil results in increased expression of ARHGEF28 mRNA

NCBI chr 2:29,263,888...29,560,595
Ensembl chr 2:29,263,886...29,560,672

G

ARF like GTPase 6 interacting protein 5

increases expression

fipronil results in increased expression of ARL6IP5 mRNA

NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608

G

asialoglycoprotein receptor 1

decreases expression

fipronil results in decreased expression of ASGR1 mRNA

NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631

G

asparaginase

increases expression

fipronil results in increased expression of ASPG mRNA

NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268

G

activating transcription factor 6

increases expression

fipronil results in increased expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

ATPase phospholipid transporting 11C

increases expression

fipronil results in increased expression of ATP11C mRNA

NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204

G

ATPase Na+/K+ transporting subunit beta 3

decreases expression

fipronil results in decreased expression of ATP1B3 mRNA

NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598

G

ATP synthase inhibitory factor subunit 1

increases expression

fipronil results in increased expression of ATP5IF1 mRNA

NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668

G

ATP synthase membrane subunit c locus 1

decreases expression

fipronil results in decreased expression of ATP5MC1 mRNA

NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124

G

ATP synthase membrane subunit c locus 1 like 2

decreases expression

fipronil results in decreased expression of ATP5MC1L2 mRNA

NCBI chr 6:66,654,187...66,654,763
Ensembl chr 6:66,654,294...66,654,692

G

ATPase H+ transporting V1 subunit E1

increases expression

fipronil results in increased expression of ATP6V1E1 mRNA

NCBI chr 4:154,022,358...154,044,486
Ensembl chr 4:154,022,358...154,044,584

G

ATR serine/threonine kinase

increases expression

fipronil results in increased expression of ATR mRNA

NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136

G

ataxin 7-like 1

decreases expression

fipronil results in decreased expression of ATXN7L1 mRNA

NCBI chr 6:49,759,876...49,982,323
Ensembl chr 6:49,759,883...49,982,320

G

ataxin 7-like 3B

affects expression

fipronil affects the expression of ATXN7L3B mRNA

NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878

G

AU RNA binding methylglutaconyl-CoA hydratase

increases expression

fipronil results in increased expression of AUH mRNA

NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

fipronil results in increased expression of AUP1 mRNA

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

G

aurora kinase A

decreases expression

fipronil results in decreased expression of AURKA mRNA

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

arginine vasopressin-induced 1

increases expression

fipronil results in increased expression of AVPI1 mRNA

NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154

G

arginine vasopressin receptor 1B

decreases expression

fipronil results in decreased expression of AVPR1B mRNA

NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792

G

alpha-2-glycoprotein 1, zinc-binding

decreases expression

fipronil results in decreased expression of AZGP1 mRNA

NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091

G

beta-1,4-galactosyltransferase 1

decreases expression

fipronil results in decreased expression of B4GALT1 mRNA

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

BAR/IMD domain containing adaptor protein 2 like 1

decreases expression

fipronil results in decreased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

Allopurinol inhibits the reaction [fipronil results in increased expression of BAX mRNA]; Plant Extracts inhibits the reaction [fipronil results in increased expression of BAX mRNA]

PMID:30777931 PMID:36916050

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCAS2, pre-mRNA processing factor

decreases expression

fipronil results in decreased expression of BCAS2 mRNA

NCBI chr 2:190,692,503...190,700,386
Ensembl chr 2:190,692,461...190,700,389

G

BCL2, apoptosis regulator

decreases expression
multiple interactions

fipronil results in decreased expression of BCL2 protein
fipronil results in decreased expression of BCL2 mRNA
Allopurinol inhibits the reaction [fipronil results in decreased expression of BCL2 mRNA]

PMID:21296133 PMID:34352653 PMID:36916050

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

brain-enriched guanylate kinase-associated

increases expression

fipronil results in increased expression of BEGAIN mRNA

NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841

G

BICD family like cargo adaptor 1

increases expression

fipronil results in increased expression of BICDL1 mRNA

NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130

G

BICD family like cargo adaptor 2

increases expression

fipronil results in increased expression of BICDL2 mRNA

NCBI chr10:12,691,610...12,700,049
Ensembl chr10:12,691,610...12,700,049

G

bridging integrator 1

increases expression

fipronil results in increased expression of BIN1 mRNA

NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263

G

bone morphogenetic protein 1

decreases expression

fipronil results in decreased expression of BMP1 mRNA

NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776

G

bone morphogenetic protein 2

increases expression

fipronil results in increased expression of BMP2 mRNA

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

brain protein I3

decreases expression

fipronil results in decreased expression of BRI3 mRNA

NCBI chr12:10,341,007...10,364,655
Ensembl chr12:10,341,011...10,364,735

G

BMP/retinoic acid inducible neural specific 2

multiple interactions

[fipronil co-treated with DEET] results in increased expression of BRINP2 mRNA

NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810

G

BRO1 domain and CAAX motif containing

decreases expression

fipronil results in decreased expression of BROX mRNA

NCBI chr13:94,920,107...94,940,189
Ensembl chr13:94,920,112...94,940,227

G

BTB domain containing 3

increases expression

fipronil results in increased expression of BTBD3 mRNA

NCBI chr 3:125,591,427...125,621,660
Ensembl chr 3:125,591,490...125,619,038

G

BTG anti-proliferation factor 1

increases expression

fipronil results in increased expression of BTG1 mRNA

NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649

G

BTG anti-proliferation factor 3

decreases expression

fipronil results in decreased expression of BTG3 mRNA

NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170

G

BUD31 homolog

decreases expression

fipronil results in decreased expression of BUD31 mRNA

NCBI chr12:9,462,838...9,470,387
Ensembl chr12:9,462,441...9,470,509

G

chromosome 11 C3orf85 homolog

decreases expression

fipronil results in decreased expression of C3ORF85 mRNA

G

similar to human chromosome 1 open reading frame 53

increases expression

fipronil results in increased expression of C13H1ORF53 mRNA

NCBI chr13:50,413,785...50,418,974
Ensembl chr13:50,413,785...50,419,120

G

similar to human chromosome 10 open reading frame 143

decreases expression
multiple interactions

fipronil results in decreased expression of C10ORF143 mRNA
[fipronil co-treated with DEET] results in decreased expression of C10ORF143 mRNA

NCBI chr 1:192,184,440...192,222,676
Ensembl chr 1:192,184,445...192,222,398

G

similar to human chromosome 15 open reading frame 40

increases expression

fipronil results in increased expression of C1H15ORF40 mRNA

NCBI chr 1:135,725,869...135,732,028
Ensembl chr 1:135,717,545...135,732,039

G

similar to human chromosome 2 open reading frame 42

decreases expression

fipronil results in decreased expression of C4H2ORF42 mRNA

NCBI chr 4:118,887,688...118,916,808
Ensembl chr 4:118,888,112...118,916,936

G

complement C8 gamma chain

increases expression

fipronil results in increased expression of C8G mRNA

NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495

G

similar to human chromosome 11 open reading frame 54

increases expression

fipronil results in increased expression of C8H11ORF54 mRNA

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 2 open reading frame 92

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of C2ORF92 mRNA
fipronil results in decreased expression of C2ORF92 mRNA

NCBI chr 9:38,943,927...38,984,878
Ensembl chr 9:38,944,526...38,985,127

G

calcium binding protein 4

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of CABP4 mRNA
fipronil results in decreased expression of CABP4 mRNA

NCBI chr 1:201,428,671...201,442,950
Ensembl chr 1:201,428,672...201,433,172

G

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

decreases expression

fipronil results in decreased expression of CAD mRNA

NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861

G

calcitonin-related polypeptide, beta

increases expression
multiple interactions

fipronil results in increased expression of CALCB mRNA
[fipronil co-treated with DEET] results in increased expression of CALCB mRNA

NCBI chr 1:168,965,383...168,970,259
Ensembl chr 1:168,966,465...168,970,125

G

calcium homeostasis modulator family member 4

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of CALHM4 mRNA
fipronil results in increased expression of CALHM4 mRNA

NCBI chr20:25,990,164...25,993,173
Ensembl chr20:25,990,462...25,993,173

G

calmodulin-like 4

increases expression

fipronil results in increased expression of CALML4 mRNA

NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234

G

calcyon neuron-specific vesicular protein

decreases expression

fipronil results in decreased expression of CALY mRNA

NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

increases expression

fipronil results in increased expression of CAMK2N1 mRNA

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

G

calpain 2

increases expression

fipronil results in increased expression of CAPN2 mRNA

NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969

G

calpain 5

increases expression

fipronil results in increased expression of CAPN5 mRNA

NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923

G

carbonic anhydrase 12

increases expression
multiple interactions

fipronil results in increased expression of CA12 mRNA
[fipronil co-treated with DEET] results in increased expression of CA12 mRNA

NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440

G

carbonic anhydrase 4

decreases expression

fipronil results in decreased expression of CA4 mRNA

NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501

G

carbonic anhydrase 8

increases expression

fipronil results in increased expression of CAR8 mRNA

NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374

G

calcium regulated heat stable protein 1

decreases expression

fipronil results in decreased expression of CARHSP1 mRNA

NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019

G

caspase 3

multiple interactions
increases activity
increases expression

kenpaullone inhibits the reaction [fipronil results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [fipronil results in increased activity of CASP3 protein]
Allopurinol inhibits the reaction [fipronil results in increased expression of CASP3 mRNA]; Plant Extracts inhibits the reaction [fipronil results in increased expression of CASP3 mRNA]
fipronil results in increased expression of CASP3 mRNA; fipronil results in increased expression of CASP3 protein

PMID:17084830 PMID:21296133 PMID:21621551 PMID:22421270 PMID:30777931 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 7

increases activity

fipronil results in increased activity of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 9

increases activity

fipronil results in increased activity of CASP9 protein

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions
decreases activity
decreases expression
affects binding
increases activity

Ascorbic Acid inhibits the reaction [fipronil results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [fipronil results in decreased activity of CAT protein]
fipronil results in decreased expression of CAT mRNA
Allopurinol inhibits the reaction [fipronil results in increased activity of CAT protein]; Plant Extracts inhibits the reaction [fipronil results in decreased activity of CAT protein]
fipronil binds to CAT protein
fipronil results in decreased expression of CAT protein

PMID:25721553 PMID:30777931 PMID:32278787 PMID:32651782 PMID:36113622 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

decreases expression

fipronil results in decreased expression of CAV1 mRNA

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

Cbl proto-oncogene

increases expression

fipronil results in increased expression of CBL mRNA

NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176

G

Cbl proto-oncogene like 1

increases expression

fipronil results in increased expression of CBLL1 mRNA

PMID:23962444 PMID:31881178

NCBI chr 6:48,071,190...48,086,174
Ensembl chr 6:48,071,190...48,086,444

G

coiled-coil domain containing 102A

increases expression

fipronil results in increased expression of CCDC102A mRNA

PMID:31881178 PMID:34044035

NCBI chr19:10,102,543...10,118,657
Ensembl chr19:10,103,361...10,118,657

G

coiled-coil domain containing 120

increases expression

fipronil results in increased expression of CCDC120 mRNA

NCBI chr X:14,753,594...14,772,745
Ensembl chr X:14,753,696...14,772,743

G

coiled-coil domain containing 136

increases expression

fipronil results in increased expression of CCDC136 mRNA

NCBI chr 4:57,997,825...58,027,598
Ensembl chr 4:57,997,853...58,027,646

G

coiled-coil domain containing 17

increases expression
decreases expression

fipronil results in increased expression of CCDC17 mRNA
fipronil results in decreased expression of CCDC17 mRNA

PMID:23962444 PMID:34044035

NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673

G

coiled-coil domain containing 200

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of CCDC200 mRNA

NCBI chr10:86,517,704...86,523,106
Ensembl chr10:86,517,683...86,523,038

G

coiled-coil domain containing 80

increases expression

fipronil results in increased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 2

decreases expression

fipronil results in decreased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

cellular communication network factor 2

increases expression

fipronil results in increased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 3

decreases expression

fipronil results in decreased expression of CCN3 mRNA

NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019

G

cyclin B1

increases expression

fipronil results in increased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin Q

increases expression

fipronil results in increased expression of CCNQ mRNA

NCBI chr10:63,646,532...63,647,695
Ensembl chr10:63,646,527...63,647,961

G

chaperonin containing TCP1 subunit 6A

decreases expression

fipronil results in decreased expression of CCT6A mRNA

NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337

G

CD14 molecule

increases expression

fipronil results in increased expression of CD14 mRNA

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD151 molecule (Raph blood group)

increases expression

fipronil results in increased expression of CD151 mRNA

NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753

G

CD302 molecule

increases expression

fipronil results in increased expression of CD302 mRNA

PMID:23962444 PMID:34044035

NCBI chr 3:44,722,324...44,756,045
Ensembl chr 3:44,722,325...44,756,045

G

CD36 molecule

decreases expression
affects expression

fipronil results in decreased expression of CD36 mRNA
fipronil affects the expression of CD36 mRNA

PMID:23962444 PMID:38050659

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD44 molecule

increases expression

fipronil results in increased expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

CD59b molecule

increases expression

fipronil results in increased expression of CD59 mRNA

NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847

G

cytidine deaminase

increases expression

fipronil results in increased expression of CDA mRNA

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

G

cyclin-dependent kinase 1

increases expression

fipronil results in increased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 11B

increases expression

fipronil results in increased expression of CDK11B mRNA

NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:166,212,829...166,238,876

G

cyclin dependent kinase 2

decreases expression

fipronil results in decreased expression of CDK2 mRNA

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 7

decreases expression

fipronil results in decreased expression of CDK7 mRNA

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

cyclin-dependent kinase inhibitor 3

increases expression

fipronil results in increased expression of CDKN3 mRNA

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CCAAT/enhancer binding protein alpha

multiple interactions
increases expression

AICA ribonucleotide inhibits the reaction [fipronil results in increased expression of CEBPA protein]
fipronil results in increased expression of CEBPA mRNA; fipronil results in increased expression of CEBPA protein

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein delta

increases expression

fipronil results in increased expression of CEBPD mRNA

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

G

centromere protein S

decreases expression

fipronil results in decreased expression of CENPS mRNA

NCBI chr 5:159,563,917...159,573,534

G

centromere protein V

decreases expression

fipronil results in decreased expression of CENPV mRNA

NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761

G

centrosomal protein 15

increases expression

fipronil results in increased expression of CEP15 mRNA

NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838

G

centrosomal protein 20

increases expression
decreases expression

fipronil results in increased expression of CEP20 mRNA
fipronil results in decreased expression of CEP20 mRNA

PMID:23962444 PMID:34044035

NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837

G

centrosomal protein 44

decreases expression

fipronil results in decreased expression of CEP44 mRNA

NCBI chr16:33,711,548...33,733,226
Ensembl chr16:33,711,559...33,733,225

G

ceramide transporter 1

increases expression

fipronil results in increased expression of CERT1 mRNA

NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074

G

carboxylesterase 2C

increases expression

fipronil results in increased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790

G

carboxylesterase 2H

increases expression

fipronil results in increased expression of CES2H mRNA

NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830

G

cilia and flagella associated protein 36

increases expression

fipronil results in increased expression of CFAP36 mRNA

NCBI chr14:102,966,006...102,991,693
Ensembl chr14:102,966,001...102,991,555

G

coiled-coil-helix-coiled-coil-helix domain containing 6

increases expression

fipronil results in increased expression of CHCHD6 mRNA

NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216

G

chromodomain helicase DNA binding protein 4

increases expression

fipronil results in increased expression of CHD4 mRNA

NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541

G

chimerin 1

increases expression

fipronil results in increased expression of CHN1 mRNA

NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490

G

chondrolectin

increases expression

fipronil results in increased expression of CHODL mRNA

NCBI chr11:17,654,137...17,676,450
Ensembl chr11:17,654,206...17,676,441

G

cholinergic receptor, muscarinic 3

increases expression

fipronil results in increased expression of CHRM3 mRNA

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

carbohydrate sulfotransferase 1

decreases expression

fipronil results in decreased expression of CHST1 mRNA

NCBI chr 3:78,552,059...78,574,740
Ensembl chr 3:78,548,525...78,574,883

G

chromatin target of PRMT1

increases expression

fipronil results in increased expression of CHTOP mRNA

NCBI chr 2:175,981,266...175,992,820
Ensembl chr 2:175,981,271...175,992,748

G

cell death-inducing DFFA-like effector a

increases expression

fipronil results in increased expression of CIDEA mRNA

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

ciliary microtubule associated protein 1B

decreases expression

fipronil results in decreased expression of CIMAP1B mRNA

NCBI chr 7:120,444,232...120,447,294
Ensembl chr 7:120,444,232...120,446,749

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

decreases expression

fipronil results in decreased expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

CDC28 protein kinase regulatory subunit 1B

decreases expression

fipronil results in decreased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

cardiotrophin-like cytokine factor 1

increases expression

fipronil results in increased expression of CLCF1 mRNA

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

G

claudin 9

increases expression

fipronil results in increased expression of CLDN9 mRNA

NCBI chr10:12,714,137...12,715,568

G

C-type lectin domain containing 14A

increases expression

fipronil results in increased expression of CLEC14A mRNA

NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612

G

C-type lectin domain family 1, member B

increases expression

fipronil results in increased expression of CLEC1B mRNA

NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291

G

CAP-GLY domain containing linker protein 1

increases expression

fipronil results in increased expression of CLIP1 mRNA

NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884

G

cytidine monophospho-N-acetylneuraminic acid hydroxylase

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of CMAHP mRNA
fipronil results in decreased expression of CMAHP mRNA

NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275

G

c-Maf-inducing protein

increases expression

fipronil results in increased expression of CMIP mRNA

NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709

G

CCHC-type zinc finger, nucleic acid binding protein

decreases expression

fipronil results in decreased expression of CNBP mRNA

NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637

G

CTD nuclear envelope phosphatase 1 regulatory subunit 1

decreases expression

fipronil results in decreased expression of CNEP1R1 mRNA

NCBI chr19:18,932,631...18,947,667
Ensembl chr19:18,932,682...18,947,667

G

cannabinoid receptor 2

increases expression

fipronil results in increased expression of CNR2 mRNA

NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548

G

collagen type IV alpha 1 chain

increases expression

fipronil results in increased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

COPI coat complex subunit epsilon

decreases expression

fipronil results in decreased expression of COPE mRNA

NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907

G

COPI coat complex subunit gamma 2

increases expression

fipronil results in increased expression of COPG2 mRNA

NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618

G

coenzyme Q4

increases expression

fipronil results in increased expression of COQ4 mRNA

NCBI chr 3:13,060,054...13,070,502
Ensembl chr 3:13,060,455...13,068,799

G

copine 4

increases expression

fipronil results in increased expression of CPNE4 mRNA

NCBI chr 8:105,177,376...105,653,075
Ensembl chr 8:105,177,376...105,653,068

G

calcineurin-like phosphoesterase domain containing 1

increases expression

fipronil results in increased expression of CPPED1 mRNA

NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054

G

carnitine palmitoyltransferase 1A

decreases expression

fipronil results in decreased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

decreases expression

fipronil results in decreased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

crumbs cell polarity complex component 3

increases expression

fipronil results in increased expression of CRB3 mRNA

NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859

G

cysteine-rich protein 2

decreases expression

fipronil results in decreased expression of CRIP2 mRNA

NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065

G

cysteine-rich protein 3

increases expression

fipronil results in increased expression of CRIP3 mRNA

NCBI chr 9:14,554,450...14,557,344
Ensembl chr 9:14,554,450...14,557,302

G

CXXC repeat containing interactor of PDZ3 domain

decreases expression

fipronil results in decreased expression of CRIPT mRNA

NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression

fipronil results in decreased expression of CRISPLD2 mRNA

NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465

G

crystallin, lambda 1

increases expression

fipronil results in increased expression of CRYL1 mRNA

NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997

G

crystallin zeta like 2

decreases expression
multiple interactions

fipronil results in decreased expression of CRYZL2P mRNA
[fipronil co-treated with DEET] results in decreased expression of CRYZL2P mRNA

NCBI chr13:69,612,605...69,655,018
Ensembl chr13:69,620,792...69,652,475

G

casein kinase 1, epsilon

increases expression

fipronil results in increased expression of CSNK1E mRNA

NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794

G

casein kinase 1, gamma 1

increases expression

fipronil results in increased expression of CSNK1G1 mRNA

NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826

G

cysteine and serine rich nuclear protein 2

decreases expression

fipronil results in decreased expression of CSRNP2 mRNA

NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075

G

cystatin C

increases expression

fipronil results in increased expression of CST3 mRNA

NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822

G

cystatin B

increases expression

fipronil results in increased expression of CSTB mRNA

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

cleavage stimulation factor subunit 2, tau variant

decreases expression

fipronil results in decreased expression of CSTF2T mRNA

NCBI chr 1:228,952,617...228,956,183
Ensembl chr 1:228,952,504...228,955,873

G

CCCTC-binding factor like 1

increases expression

fipronil results in increased expression of CTCFL mRNA

NCBI chr 3:161,868,306...161,890,949
Ensembl chr 3:161,868,306...161,890,949

G

catenin beta 1

decreases expression

fipronil results in decreased expression of CTNNB1 mRNA

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

cathepsin B

increases expression

fipronil results in increased expression of CTSB mRNA

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin H

decreases expression

fipronil results in decreased expression of CTSH mRNA

NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824

G

cortexin 1

decreases expression

fipronil results in decreased expression of CTXN1 mRNA

NCBI chr12:2,610,465...2,612,076

G

C-X3-C motif chemokine ligand 1

increases expression

fipronil results in increased expression of CX3CL1 mRNA

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X-C motif chemokine ligand 12

decreases expression

fipronil results in decreased expression of CXCL12 mRNA

PMID:23962444 PMID:34044035

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

cytochrome b5 type A

increases expression
multiple interactions

fipronil results in increased expression of CYB5A mRNA
[fipronil co-treated with DEET] results in increased expression of CYB5A mRNA

PMID:23962444 PMID:27091632

NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535

G

cytochrome c, somatic

affects localization

fipronil affects the localization of CYCS protein

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome P450, family 1, subfamily a, polypeptide 1

affects activity
multiple interactions
increases expression

fipronil affects the activity of CYP1A1 protein
[fipronil co-treated with DEET] results in increased expression of CYP1A1 mRNA
fipronil results in increased expression of CYP1A1 mRNA

PMID:17084830 PMID:27091632

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

[fipronil co-treated with DEET] results in increased expression of CYP1A2 mRNA

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 20, subfamily a, polypeptide 1

increases expression
multiple interactions
decreases expression

fipronil results in increased expression of CYP20A1 mRNA
[fipronil co-treated with DEET] results in decreased expression of CYP20A1 mRNA
fipronil results in decreased expression of CYP20A1 mRNA

PMID:23962444 PMID:27091632

NCBI chr 9:61,755,804...61,805,123
Ensembl chr 9:61,755,790...61,805,123

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of CYP26A1 mRNA
fipronil results in increased expression of CYP26A1 mRNA

NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204

G

cytochrome P450, family 26, subfamily b, polypeptide 1

increases expression
multiple interactions

fipronil results in increased expression of CYP26B1 mRNA
[fipronil co-treated with DEET] results in increased expression of CYP26B1 mRNA

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 2, subfamily a, polypeptide 1

increases expression

fipronil results in increased expression of CYP2A1 mRNA

NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887

G

cytochrome P450, family 2, subfamily a, polypeptide 3

multiple interactions

[fipronil co-treated with DEET] results in increased expression of CYP2A7 mRNA

NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979

G

cytochrome P450, family 2, subfamily b, polypeptide 1

increases expression

fipronil results in increased expression of CYP2B1 mRNA

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 2

increases expression

fipronil results in increased expression of CYP2B2 mRNA

PMID:22447239 PMID:23962444

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression
multiple interactions

fipronil results in increased expression of CYP2B6 mRNA
[fipronil co-treated with DEET] results in increased expression of CYP2B6 mRNA
fipronil results in increased expression of CYP2B10 mRNA
NR1I3 gene mutant form inhibits the reaction [fipronil results in increased expression of CYP2B10 mRNA]

PMID:17084830 PMID:23962444 PMID:27091632

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily c, polypeptide 22

increases expression

fipronil results in increased expression of CYP2C22 mRNA

NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions
increases expression

[fipronil co-treated with DEET] results in decreased expression of CYP2C19 mRNA
fipronil results in increased expression of CYP2C29 mRNA

PMID:23962444 PMID:27091632

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily c, polypeptide 79

increases expression
multiple interactions

fipronil results in increased expression of CYP2C8 mRNA
[fipronil co-treated with DEET] results in increased expression of CYP2C8 mRNA

G

cytochrome P450, family 2, subfamily d, polypeptide 1

increases expression

fipronil results in increased expression of CYP2D7 mRNA

NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084

G

cytochrome P450, family 2, subfamily d, polypeptide 2

increases expression

fipronil results in increased expression of CYP2D2 mRNA

NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases activity

fipronil results in decreased activity of CYP2D6 protein

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression
decreases expression
multiple interactions
affects expression

fipronil results in increased expression of CYP2E1 mRNA
fipronil results in decreased expression of CYP2E1 mRNA
[fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA
fipronil affects the expression of CYP2E1 mRNA

PMID:23962444 PMID:27091632 PMID:38050659

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 18

increases expression
multiple interactions

fipronil results in increased expression of CYP3A18 mRNA
fipronil results in increased expression of CYP3A43 mRNA
[fipronil co-treated with DEET] results in increased expression of CYP3A43 mRNA

PMID:23962444 PMID:27091632

NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression
multiple interactions

fipronil results in increased expression of CYP3A2 mRNA
[fipronil co-treated with DEET] results in increased expression of CYP3A4 mRNA; fipronil promotes the reaction [[CYP3A4 protein results in increased metabolism of Testosterone] which results in increased chemical synthesis of 6 beta-hydroxytestosterone]; fipronil results in increased expression of and results in increased activity of CYP3A4 protein
fipronil results in increased expression of CYP3A4 mRNA
fipronil results in increased expression of CYP3A11 mRNA
NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of CYP3A11 mRNA]

PMID:17084830 PMID:23962444 PMID:27091632

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

increases expression

fipronil results in increased expression of CYP3A23-3A1 mRNA

PMID:22447239 PMID:23962444

NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030

G

cytochrome P450, family 3, subfamily a, polypeptide 62

increases expression

fipronil results in increased expression of CYP3A62 mRNA

NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases expression
multiple interactions

fipronil results in increased expression of CYP3A9 mRNA
fipronil results in increased expression of CYP3A5 mRNA
[fipronil co-treated with DEET] results in increased expression of CYP3A5 mRNA

PMID:17084830 PMID:23962444 PMID:27091632

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 46, subfamily a, polypeptide 1

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of CYP46A1 mRNA

NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760

G

cytochrome P450, family 4, subfamily a, polypeptide 1

decreases expression
multiple interactions

fipronil results in decreased expression of CYP4A1 mRNA
[fipronil co-treated with DEET] results in decreased expression of CYP4A22 mRNA
fipronil results in decreased expression of CYP4A22 mRNA

PMID:23962444 PMID:27091632

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 4, subfamily a, polypeptide 3

decreases expression

fipronil results in decreased expression of CYP4A3 mRNA

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

G

cytochrome P450, family 4, subfamily a, polypeptide 8

decreases expression

fipronil results in decreased expression of CYP4A8 mRNA

NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476

G

cytochrome P450, family 4, subfamily f, polypeptide 1

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of CYP4F12 mRNA

NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046

G

cytochrome P450, family 4, subfamily f, polypeptide 39

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of CYP4F22 mRNA
fipronil results in increased expression of CYP4F22 mRNA

NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181

G

cytochrome P450, family 4, subfamily v, polypeptide 3

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of CYP4V2 mRNA
fipronil results in decreased expression of CYP4V2 mRNA

NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395

G

cytochrome P450, family 51

increases expression

fipronil results in increased expression of CYP51A1 mRNA

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410

G

cytochrome P450 family 7 subfamily A member 1

decreases expression
increases expression

fipronil results in decreased expression of CYP7A1 protein
fipronil results in increased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 8 subfamily B member 1

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of CYP8B1 mRNA
fipronil results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

cysteine and tyrosine rich 1

increases expression

fipronil results in increased expression of CYYR1 mRNA

NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961

G

DAB adaptor protein 2

increases expression

fipronil results in increased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

dystroglycan 1

increases expression

fipronil results in increased expression of DAG1 mRNA

NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325

G

differentiation antagonizing non-protein coding RNA

increases expression
multiple interactions

fipronil results in increased expression of DANCR mRNA
[fipronil co-treated with DEET] results in increased expression of DANCR mRNA

NCBI chr14:34,126,956...34,127,936

G

death-associated protein

increases expression

fipronil results in increased expression of DAP mRNA

NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

increases expression

fipronil results in increased expression of DAPP1 mRNA

NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423

G

death-domain associated protein

decreases expression

fipronil results in decreased expression of DAXX mRNA

NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843

G

dysbindin domain containing 2

increases expression

fipronil results in increased expression of DBNDD2 mRNA

NCBI chr 3:153,216,300...153,220,651
Ensembl chr 3:153,191,090...153,220,651

G

D-box binding PAR bZIP transcription factor

increases expression

fipronil results in increased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

DDB1 and CUL4 associated factor 13

decreases expression

fipronil results in decreased expression of DCAF13 mRNA

NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142

G

dachsous cadherin-related 1

increases expression

fipronil results in increased expression of DCHS1 mRNA

NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808

G

DEAD-box helicase 17

increases expression

fipronil results in increased expression of DDX17 mRNA

NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193

G

DExD-box helicase 52

decreases expression

fipronil results in decreased expression of DDX52 mRNA

NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266

G

DENN domain containing 2A

increases expression

fipronil results in increased expression of DENND2A mRNA

NCBI chr 4:68,233,016...68,332,235
Ensembl chr 4:68,233,958...68,332,105

G

DENN domain containing 2B

increases expression

fipronil results in increased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

DEP domain containing 5, GATOR1 subcomplex subunit

decreases expression

fipronil results in decreased expression of DEPDC5 mRNA

NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794

G

Dexi homolog

increases expression

fipronil results in increased expression of DEXI mRNA

NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738

G

diacylglycerol kinase, alpha

increases expression

fipronil results in increased expression of DGKA mRNA

NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110

G

diacylglycerol kinase, delta

increases expression

fipronil results in increased expression of DGKD mRNA

NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345

G

iodothyronine deiodinase 1

decreases expression
increases expression
multiple interactions
decreases activity

fipronil results in decreased expression of DIO1 mRNA
fipronil results in increased expression of DIO1 mRNA
[fipronil co-treated with DEET] results in increased expression of DIO1 mRNA
fipronil results in decreased activity of DIO1 protein

PMID:23962444 PMID:27091632 PMID:29228274 PMID:30561685

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

iodothyronine deiodinase 2

decreases activity

fipronil results in decreased activity of DIO2 protein

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

iodothyronine deiodinase 3

increases expression
decreases activity

fipronil results in increased expression of DIO3 mRNA
fipronil results in decreased activity of DIO3 protein

PMID:23962444 PMID:30561685

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

DIO3 opposite strand upstream RNA

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of DIO3OS mRNA

G

disco-interacting protein 2 homolog A

increases expression

fipronil results in increased expression of DIP2A mRNA

NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217

G

dispatched RND transporter family member 1

decreases expression

fipronil results in decreased expression of DISP1 mRNA

NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702

G

discs large MAGUK scaffold protein 1

increases expression

fipronil results in increased expression of DLG1 mRNA

NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689

G

discs large MAGUK scaffold protein 5 like 17

decreases expression

fipronil results in decreased expression of DLG5L17 mRNA

NCBI chr 8:38,165,288...38,171,353
Ensembl chr 8:38,167,231...38,192,620

G

delta like non-canonical Notch ligand 1

increases expression

fipronil results in increased expression of DLK1 mRNA

NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522

G

DM1 protein kinase

increases expression

fipronil results in increased expression of DMPK mRNA

NCBI chr 1:78,730,255...78,740,585
Ensembl chr 1:78,730,275...78,740,593

G

dynein axonemal assembly factor 10

decreases expression

fipronil results in decreased expression of DNAAF10 mRNA

NCBI chr14:91,618,649...91,639,828
Ensembl chr14:91,636,157...91,639,831

G

dynein, axonemal, assembly factor 2

decreases expression

fipronil results in decreased expression of DNAAF2 mRNA

NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199

G

DnaJ heat shock protein family (Hsp40) member B11

decreases expression

fipronil results in decreased expression of DNAJB11 mRNA

NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407

G

deoxyribonuclease 1L3

increases expression

fipronil results in increased expression of DNASE1L3 mRNA

NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317

G

dedicator of cytokinesis 6

increases expression

fipronil results in increased expression of DOCK6 mRNA

NCBI chr 8:20,342,430...20,394,660
Ensembl chr 8:20,342,089...20,394,552

G

DNA replication fork stabilization factor DONSON

increases expression

fipronil results in increased expression of DONSON mRNA

NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889

G

dpy-30 histone methyltransferase complex regulatory subunit

decreases expression

fipronil results in decreased expression of DPY30 mRNA

NCBI chr 6:21,120,947...21,141,720
Ensembl chr 6:21,120,947...21,141,432

G

DNA replication and sister chromatid cohesion 1

decreases expression

fipronil results in decreased expression of DSCC1 mRNA

NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212

G

dermatan sulfate epimerase

increases expression

fipronil results in increased expression of DSE mRNA

NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992

G

desmoplakin

increases expression

fipronil results in increased expression of DSP mRNA

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

destrin, actin depolymerizing factor

decreases expression

fipronil results in decreased expression of DSTN mRNA

NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379

G

deltex E3 ubiquitin ligase 3L

decreases expression

fipronil results in decreased expression of DTX3L mRNA

NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538

G

dual oxidase maturation factor 1

increases expression

fipronil results in increased expression of DUOXA1 mRNA

NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499

G

dual specificity phosphatase 16

increases expression

fipronil results in increased expression of DUSP16 mRNA

NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980

G

dynein cytoplasmic 1 heavy chain 1

increases expression

fipronil results in increased expression of DYNC1H1 mRNA

NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883

G

dynein, cytoplasmic 1 light intermediate chain 2

increases expression

fipronil results in increased expression of DYNC1LI2 mRNA

NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670

G

dynein 2 intermediate chain 2

increases expression

fipronil results in increased expression of DYNC2I2 mRNA

NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121

G

dynein light chain Tctex-type 1

increases expression

fipronil results in increased expression of DYNLT1 mRNA

NCBI chr 1:46,887,017...46,893,956
Ensembl chr 1:46,887,017...46,893,881

G

EBNA1 binding protein 2

decreases expression

fipronil results in decreased expression of EBNA1BP2 mRNA

NCBI chr 5:132,148,164...132,152,730
Ensembl chr 5:132,148,143...132,153,267

G

extracellular matrix protein 1

increases expression

fipronil results in increased expression of ECM1 mRNA

NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671

G

embryonic ectoderm development

decreases expression

fipronil results in decreased expression of EED mRNA

NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974

G

EEF1A lysine methyltransferase 2

increases expression

fipronil results in increased expression of EEF1AKMT2 mRNA

NCBI chr 1:187,616,156...187,640,934
Ensembl chr 1:187,500,744...187,640,937

G

eukaryotic translation elongation factor 1 delta

decreases expression

fipronil results in decreased expression of EEF1D mRNA

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

EF-hand calcium binding domain 6

decreases expression

fipronil results in decreased expression of EFCAB6 mRNA

NCBI chr 7:115,018,971...115,200,121
Ensembl chr 7:115,019,010...115,206,092

G

EGF-like-domain, multiple 7

increases expression

fipronil results in increased expression of EGFL7 mRNA

NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879

G

eukaryotic translation initiation factor 1A, X-linked

decreases expression

fipronil results in decreased expression of EIF1AX mRNA

NCBI chr X:35,498,698...35,513,402
Ensembl chr X:35,498,517...35,513,335

G

eukaryotic translation initiation factor 3, subunit F

increases expression

fipronil results in increased expression of EIF3F mRNA

NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204

G

eukaryotic translation initiation factor 4A3

decreases expression

fipronil results in decreased expression of EIF4A3 mRNA

NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057

G

eukaryotic translation initiation factor 6

decreases expression

fipronil results in decreased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

extracellular leucine-rich repeat and fibronectin type III domain containing 2

decreases expression

fipronil results in decreased expression of ELFN2 mRNA

NCBI chr 7:110,220,293...110,272,770
Ensembl chr 7:110,225,919...110,272,433

G

elongation factor 1

decreases expression

fipronil results in decreased expression of ELOF1 mRNA

NCBI chr 8:20,645,336...20,650,888
Ensembl chr 8:20,645,336...20,650,579

G

ELOVL fatty acid elongase 2

increases expression

fipronil results in increased expression of ELOVL2 mRNA

NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848

G

ELOVL fatty acid elongase 5

decreases expression

fipronil results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

endomucin

increases expression

fipronil results in increased expression of EMCN mRNA

NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

increases expression

fipronil results in increased expression of ENPP1 mRNA

NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715

G

ectonucleoside triphosphate diphosphohydrolase 6

increases expression

fipronil results in increased expression of ENTPD6 mRNA

NCBI chr 3:139,575,659...139,598,163
Ensembl chr 3:139,575,686...139,598,154

G

endosomal transmembrane epsin interactor 3

decreases expression

fipronil results in decreased expression of ENTREP3 mRNA

NCBI chr 2:174,588,984...174,595,281
Ensembl chr 2:174,589,337...174,595,281

G

exosomal polycystin 1 interacting protein

decreases expression
multiple interactions

fipronil results in decreased expression of EPCIP mRNA
[fipronil co-treated with DEET] results in decreased expression of EPCIP mRNA

NCBI chr11:30,307,842...30,325,829
Ensembl chr11:30,310,350...30,325,439

G

epoxide hydrolase 1

increases expression

fipronil results in increased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

erb-b2 receptor tyrosine kinase 2

increases expression

fipronil results in increased expression of ERBB2 mRNA

NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078

G

esterase D

increases expression

fipronil results in increased expression of ESD mRNA

NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144

G

estrogen receptor 1

decreases expression
multiple interactions

fipronil results in decreased expression of ESR1 mRNA
[fipronil co-treated with DEET] results in decreased expression of ESR1 mRNA
fipronil inhibits the reaction [Estradiol results in increased activity of ESR1 protein]

PMID:27091632 PMID:28531659 PMID:38050659

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of ESR2 mRNA
fipronil results in decreased expression of ESR2 mRNA

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

electron transfer flavoprotein subunit beta

decreases expression

fipronil results in decreased expression of ETFB mRNA

NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068

G

ETHE1, persulfide dioxygenase

increases expression

fipronil results in increased expression of ETHE1 mRNA

NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052

G

ethanolamine kinase 2

increases expression

fipronil results in increased expression of ETNK2 mRNA

NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037

G

eva-1 homolog A, regulator of programmed cell death

increases expression

fipronil results in increased expression of EVA1A mRNA

NCBI chr 4:114,593,773...114,643,011
Ensembl chr 4:114,593,341...114,643,011

G

exocyst complex component 2

decreases expression

fipronil results in decreased expression of EXOC2 mRNA

NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289

G

ezrin

decreases expression

fipronil results in decreased expression of EZR mRNA

NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505

G

coagulation factor VIII

increases expression

fipronil results in increased expression of F8 mRNA

PMID:23962444 PMID:31881178

NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857

G

fatty acid binding protein 4

increases expression

fipronil results in increased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

family with sequence similarity 118, member A

increases expression

fipronil results in increased expression of FAM118A mRNA

NCBI chr 7:116,152,448...116,178,976
Ensembl chr 7:116,146,716...116,178,971

G

family with sequence similarity 162, member A

decreases expression

fipronil results in decreased expression of FAM162A mRNA

NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239

G

family with sequence similarity 171, member A1

increases expression

fipronil results in increased expression of FAM171A1 mRNA

NCBI chr17:75,024,582...75,148,348
Ensembl chr17:75,024,575...75,150,255

G

family with sequence similarity 174 member C

decreases expression

fipronil results in decreased expression of FAM174C mRNA

NCBI chr 7:9,531,995...9,533,705

G

FAM20C, golgi associated secretory pathway kinase

decreases expression

fipronil results in decreased expression of FAM20C mRNA

NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543

G

family with sequence similarity 210, member B

increases expression

fipronil results in increased expression of FAM210B mRNA

NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397

G

FAM3 metabolism regulating signaling molecule C

decreases expression

fipronil results in decreased expression of FAM3C mRNA

NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078

G

phenylalanyl-tRNA synthetase subunit alpha

decreases expression

fipronil results in decreased expression of FARSA mRNA

NCBI chr19:23,291,409...23,300,985
Ensembl chr19:23,268,869...23,300,980

G

fatty acid synthase

increases expression

fipronil results in increased expression of FASN mRNA; fipronil results in increased expression of FASN protein

PMID:27103584 PMID:38050659

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

Fas binding factor 1

increases expression

fipronil results in increased expression of FBF1 mRNA

NCBI chr10:101,375,769...101,401,624
Ensembl chr10:101,375,775...101,401,644

G

fibrillarin-like 1

increases expression
multiple interactions

fipronil results in increased expression of FBLL1 mRNA
[fipronil co-treated with DEET] results in increased expression of FBLL1 mRNA

NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299

G

fructose-bisphosphatase 1

decreases expression

fipronil results in decreased expression of FBP1 mRNA

NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071

G

F-box and leucine-rich repeat protein 4

increases expression

fipronil results in increased expression of FBXL4 mRNA

NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443

G

F-box protein 27

increases expression

fipronil results in increased expression of FBXO27 mRNA

NCBI chr 1:83,965,426...83,987,781
Ensembl chr 1:83,965,986...83,987,778

G

F-box and WD repeat domain containing 5

decreases expression

fipronil results in decreased expression of FBXW5 mRNA

NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092

G

Fc alpha receptor

decreases expression

fipronil results in decreased expression of FCAR mRNA

NCBI chr 1:69,626,458...69,660,558

G

Fc gamma receptor 2A

increases expression

fipronil results in increased expression of FCGR2A mRNA

PMID:23962444 PMID:34044035

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

Fc gamma receptor 2B

increases expression

fipronil results in increased expression of FCGR2B mRNA

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

G

Fc gamma receptor and transporter

decreases expression

fipronil results in decreased expression of FCGRT mRNA

NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084

G

FERM domain containing kindlin 2

increases expression

fipronil results in increased expression of FERMT2 mRNA

NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811

G

fibroblast growth factor 1

increases expression

fipronil results in increased expression of FGF1 mRNA

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fumarate hydratase

decreases expression

fipronil results in decreased expression of FH mRNA

NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266

G

fat storage-inducing transmembrane protein 2

decreases expression

fipronil results in decreased expression of FITM2 mRNA

NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858

G

flotillin 1

increases expression

fipronil results in increased expression of FLOT1 mRNA

NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978

G

Fms related receptor tyrosine kinase 1

increases expression

fipronil results in increased expression of FLT1 mRNA

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

formin binding protein 1

increases expression

fipronil results in increased expression of FNBP1 mRNA

NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881

G

fibronectin type III domain containing 5

increases expression

fipronil results in increased expression of FNDC5 mRNA

NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731

G

folliculin interacting protein 2

increases expression

fipronil results in increased expression of FNIP2 mRNA

NCBI chr 2:164,596,557...164,708,147
Ensembl chr 2:164,598,906...164,707,901

G

forkhead box M1

increases expression

fipronil results in increased expression of FOXM1 mRNA

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O4

decreases expression

fipronil results in decreased expression of FOXO4 mRNA

NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115

G

follistatin

decreases expression

fipronil results in decreased expression of FST mRNA

NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571

G

ferritin heavy chain 1

increases expression

fipronil results in increased expression of FTH1 mRNA

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

increases expression

fipronil results in increased expression of FTL1 mRNA

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

FTX transcript, XIST regulator

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of FTX mRNA

NCBI chr X:68,588,349...68,630,338

G

alpha-L-fucosidase 2

increases expression

fipronil results in increased expression of FUCA2 mRNA

NCBI chr 1:7,885,986...7,900,777
Ensembl chr 1:7,885,918...7,900,776

G

fucosyltransferase 4

increases expression

fipronil results in increased expression of FUT4 mRNA

NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

fipronil results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

alpha glucosidase

increases expression

fipronil results in increased expression of GAA mRNA

NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836

G

gamma-aminobutyric acid type A receptor subunit alpha 1

multiple interactions

fipronil promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]

NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864

G

gamma-aminobutyric acid type A receptor subunit alpha 2

multiple interactions

fipronil results in decreased activity of [GABRA2 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB3]

NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944

G

gamma-aminobutyric acid type A receptor subunit alpha 4

multiple interactions

fipronil results in decreased activity of [GABRA4 protein binds to GABRB3 binds to GABRD protein]; fipronil results in decreased activity of [GABRA4 protein binds to GABRB3 binds to GABRG2 protein alternative form]

NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844

G

gamma-aminobutyric acid type A receptor subunit alpha6

multiple interactions

fipronil results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]

NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769

G

gamma-aminobutyric acid type A receptor subunit beta1

affects binding
multiple interactions

fipronil binds to GABRB1 protein
fipronil results in decreased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]

PMID:11489356 PMID:29038840

NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

fipronil promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

G

gamma-aminobutyric acid type A receptor subunit beta 3

affects binding
multiple interactions
decreases phosphorylation

fipronil binds to GABRB3 protein
fipronil inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB3]; fipronil results in decreased activity of [GABRA4 protein binds to GABRB3 binds to GABRD protein]; fipronil results in decreased activity of [GABRA4 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]
fipronil results in decreased phosphorylation of GABRB3 protein

PMID:11312652 PMID:11489356 PMID:16537435 PMID:29038840 PMID:32294523

NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961

G

gamma-aminobutyric acid type A receptor subunit delta

multiple interactions

fipronil results in decreased activity of [GABRA4 protein binds to GABRB3 binds to GABRD protein]

NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411

G

gamma-aminobutyric acid type A receptor subunit gamma 2

multiple interactions

fipronil promotes the reaction [tetramethylenedisulfotetramine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]]]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA4 protein binds to GABRB3 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB1 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]; fipronil results in decreased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

growth arrest and DNA-damage-inducible, beta

increases expression

fipronil results in increased expression of GADD45B mRNA

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

growth arrest-specific 2

increases expression

fipronil results in increased expression of GAS2 mRNA

NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619

G

growth arrest specific 5

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of GAS5 mRNA
fipronil results in increased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

growth arrest specific 6

decreases expression

fipronil results in decreased expression of GAS6 mRNA

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

golgi associated kinase 1A

decreases expression

fipronil results in decreased expression of GASK1A mRNA

NCBI chr 8:121,610,779...121,643,742
Ensembl chr 8:121,610,787...121,642,942

G

glycine amidinotransferase

increases expression

fipronil results in increased expression of GATM mRNA

NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129

G

GC-rich sequence DNA-binding factor 2

decreases expression

fipronil results in decreased expression of GCFC2 mRNA

NCBI chr 4:114,481,613...114,519,268
Ensembl chr 4:114,481,607...114,519,962

G

glucagon

increases expression

fipronil results in increased expression of GCG mRNA

NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929

G

glutamate-cysteine ligase, catalytic subunit

increases expression

fipronil results in increased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

growth differentiation factor 6

decreases expression

fipronil results in decreased expression of GDF6 mRNA

NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567

G

gem (nuclear organelle) associated protein 6

decreases expression

fipronil results in decreased expression of GEMIN6 mRNA

NCBI chr 6:14,786,090...14,790,617
Ensembl chr 6:14,786,070...14,790,612

G

glial fibrillary acidic protein

increases expression

fipronil results in increased expression of GFAP protein

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

glutamine fructose-6-phosphate transaminase 1

increases expression

fipronil results in increased expression of GFPT1 mRNA

NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471

G

gamma-glutamyl cyclotransferase

increases expression

fipronil results in increased expression of GGCT mRNA

NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277

G

gamma-glutamyltransferase 1

increases expression

fipronil results in increased expression of GGT1 mRNA

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

G

growth hormone inducible transmembrane protein

increases expression

fipronil results in increased expression of GHITM mRNA

NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879

G

growth hormone receptor

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

GID complex subunit 8 homolog

decreases expression

fipronil results in decreased expression of GID8 mRNA

NCBI chr 3:167,826,006...167,836,759
Ensembl chr 3:167,826,060...167,834,814

G

GIPC PDZ domain containing family, member 2

decreases expression

fipronil results in decreased expression of GIPC2 mRNA

NCBI chr 2:241,030,764...241,110,236
Ensembl chr 2:241,030,770...241,110,236

G

galactosidase, beta 1

increases expression

fipronil results in increased expression of GLB1 mRNA

NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127

G

golgi glycoprotein 1

increases expression

fipronil results in increased expression of GLG1 mRNA

NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178

G

glycosylated lysosomal membrane protein

increases expression

fipronil results in increased expression of GLMP mRNA

NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960

G

glycine receptor, alpha 1

decreases activity

fipronil results in decreased activity of GLRA1 protein

NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162

G

glycine receptor, alpha 2

decreases activity

fipronil results in decreased activity of GLRA2 protein

NCBI chr X:29,020,377...29,241,666
Ensembl chr X:29,020,557...29,241,666

G

glycine receptor, alpha 3

decreases activity

fipronil results in decreased activity of GLRA3 protein

NCBI chr16:34,199,937...34,848,773
Ensembl chr16:34,204,811...34,848,753

G

glutaredoxin 5

decreases expression

fipronil results in decreased expression of GLRX5 mRNA

NCBI chr 6:123,988,461...123,998,545
Ensembl chr 6:123,988,134...123,998,545

G

glycine-N-acyltransferase

decreases expression

fipronil results in decreased expression of GLYAT mRNA

NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942

G

guanosine monophosphate reductase 2

increases expression

fipronil results in increased expression of GMPR2 mRNA

NCBI chr15:29,165,421...29,175,933
Ensembl chr15:29,165,783...29,174,935

G

G protein subunit alpha 12

increases expression

fipronil results in increased expression of GNA12 mRNA

NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255

G

G protein subunit alpha transducin 3

decreases expression

fipronil results in decreased expression of GNAT3 mRNA

NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283

G

G protein subunit beta 1

increases expression

fipronil results in increased expression of GNB1 mRNA

NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

fipronil results in decreased expression of GNE mRNA

NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499

G

G protein subunit gamma 12

decreases expression

fipronil results in decreased expression of GNG12 mRNA

NCBI chr 4:96,011,118...96,134,767
Ensembl chr 4:96,010,952...96,134,712

G

glucose-6-phosphate isomerase

increases expression

fipronil results in increased expression of GPI mRNA

NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

fipronil results in decreased expression of GPLD1 mRNA

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

G

G-protein signaling modulator 1

increases expression

fipronil results in increased expression of GPSM1 mRNA

NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827

G

glutamic--pyruvic transaminase

increases expression
increases activity
multiple interactions

fipronil results in increased expression of GPT protein
fipronil results in increased activity of GPT protein
Plant Extracts inhibits the reaction [fipronil results in increased activity of GPT protein]
[imidacloprid co-treated with fipronil co-treated with Glyphosate] results in increased activity of and results in increased secretion of GPT protein; fipronil results in increased activity of and results in increased secretion of GPT protein

PMID:25721553 PMID:32651782 PMID:35850439

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

increases expression

fipronil results in increased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

growth regulating estrogen receptor binding 1

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of GREB1 mRNA
fipronil results in decreased expression of GREB1 mRNA

NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633

G

glycine rich extracellular protein 1

decreases expression
multiple interactions

fipronil results in decreased expression of GREP1 mRNA
[fipronil co-treated with DEET] results in decreased expression of GREP1 mRNA

NCBI chr10:12,727,164...12,748,629
Ensembl chr10:12,727,166...12,741,819

G

G protein-coupled receptor kinase 5

increases expression

fipronil results in increased expression of GRK5 mRNA

NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701

G

germ cell associated 1

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of GSG1 mRNA

NCBI chr 4:168,090,773...168,107,039
Ensembl chr 4:168,090,776...168,107,039

G

glycogen synthase kinase 3 beta

decreases phosphorylation
multiple interactions
affects response to substance

fipronil results in decreased phosphorylation of GSK3B protein
kenpaullone inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein]
GSK3B protein affects the susceptibility to fipronil

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

GSK3B interacting protein

decreases expression

fipronil results in decreased expression of GSKIP mRNA

NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100

G

gelsolin

decreases expression

fipronil results in decreased expression of GSN mRNA

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

G

G1 to S phase transition 1

decreases expression

fipronil results in decreased expression of GSPT1 mRNA

NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198

G

glutathione-disulfide reductase

increases expression

fipronil results in increased expression of GSR mRNA

PMID:23962444 PMID:38050659

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 2

increases expression
multiple interactions

fipronil results in increased expression of GSTA2 mRNA
[fipronil co-treated with DEET] results in increased expression of GSTA2 mRNA

PMID:23962444 PMID:27091632

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 4

increases expression

fipronil results in increased expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase alpha 5

increases expression

fipronil results in increased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

increases expression

fipronil results in increased expression of GSTM1 mRNA

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

increases expression

fipronil results in increased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

increases expression

fipronil results in increased expression of GSTP1 mRNA

PMID:23962444 PMID:31881178

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 2

decreases expression

fipronil results in decreased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

general transcription factor 2A subunit 2

decreases expression

fipronil results in decreased expression of GTF2A2 mRNA

NCBI chr 8:70,662,447...70,675,576
Ensembl chr 8:70,662,428...70,675,569

G

GTF2I repeat domain containing 2

decreases expression

fipronil results in decreased expression of GTF2IRD2 mRNA

NCBI chr12:22,497,767...22,536,455
Ensembl chr12:22,498,091...22,536,263

G

GTP binding protein 2

increases expression

fipronil results in increased expression of GTPBP2 mRNA

NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241

G

guanylate cyclase 1 soluble subunit beta 2

increases expression

fipronil results in increased expression of GUCY1B2 mRNA

NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441

G

glycogenin 1

increases expression

fipronil results in increased expression of GYG1 mRNA

NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797

G

glycophorin C

increases expression

fipronil results in increased expression of GYPC mRNA

NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204

G

H19 imprinted maternally expressed transcript

increases expression
multiple interactions

fipronil results in increased expression of H19 mRNA
[fipronil co-treated with DEET] results in increased expression of H19 mRNA

NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134

G

H1.0 linker histone

increases expression

fipronil results in increased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.4 linker histone, cluster member

increases expression

fipronil results in increased expression of H1F4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

H2A clustered histone 25

decreases expression

fipronil results in decreased expression of H2AC25 mRNA

NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874

G

H2A.Z variant histone 1

decreases expression

fipronil results in decreased expression of H2AZ1 mRNA

NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485

G

H2A.Z variant histone 2

decreases expression

fipronil results in decreased expression of H2AZ2 mRNA

NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144

G

H3.3 histone A

decreases expression

fipronil results in decreased expression of H3F3A mRNA

NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908

G

3-hydroxyacyl-CoA dehydratase 3

decreases expression

fipronil results in decreased expression of HACD3 mRNA

NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

fipronil results in decreased expression of HADHA mRNA

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

histidine ammonia lyase

decreases expression

fipronil results in decreased expression of HAL mRNA

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hyaluronan and proteoglycan link protein 2

decreases expression

fipronil results in decreased expression of HAPLN2 mRNA

NCBI chr 2:173,488,909...173,496,824
Ensembl chr 2:173,491,160...173,496,588

G

histone acetyltransferase 1

increases expression

fipronil results in increased expression of HAT1 mRNA

NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517

G

HAUS augmin like complex subunit 2

increases expression

fipronil results in increased expression of HAUS2 mRNA

NCBI chr 3:107,553,146...107,565,982
Ensembl chr 3:107,553,161...107,565,157

G

hemoglobin subunit gamma 1

decreases expression

fipronil results in decreased expression of HBG1 mRNA

NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425

G

host cell factor C1 regulator 1

increases expression

fipronil results in increased expression of HCFC1R1 mRNA

NCBI chr10:12,705,139...12,706,852
Ensembl chr10:12,705,077...12,706,850

G

histidine decarboxylase

increases expression

fipronil results in increased expression of HDC mRNA

NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341

G

hematopoietically expressed homeobox

increases expression

fipronil results in increased expression of HHEX mRNA

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

hypoxia inducible factor 1 subunit alpha

decreases expression

fipronil results in decreased expression of HIF1A mRNA

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

huntingtin interacting protein 1 related

increases expression

fipronil results in increased expression of HIP1R mRNA

NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734

G

histone cluster 1 H2A family member C

decreases expression

fipronil results in decreased expression of HIST1H2AC mRNA

NCBI chr17:42,478,836...42,479,306
Ensembl chr17:41,534,691...41,539,869
Ensembl chr17:41,534,691...41,539,869

G

histone cluster 1, H2an

decreases expression

fipronil results in decreased expression of HIST1H2AN mRNA

NCBI chr17:41,534,653...41,535,259
Ensembl chr17:41,534,691...41,539,869

G

3-hydroxy-3-methylglutaryl-CoA lyase

decreases expression

fipronil results in decreased expression of HMGCL mRNA

NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression
multiple interactions

fipronil results in decreased expression of HMGCS2 mRNA
[fipronil co-treated with DEET] results in decreased expression of HMGCS2 mRNA

PMID:23962444 PMID:27091632

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

high mobility group nucleosomal binding domain 2

decreases expression

fipronil results in decreased expression of HMGN2 mRNA

NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
Ensembl chr16:146,192,126...146,195,521

G

high mobility group nucleosomal binding domain 3

increases expression

fipronil results in increased expression of HMGN3 mRNA

NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976

G

heterogeneous nuclear ribonucleoprotein K

decreases expression

fipronil results in decreased expression of HNRNPK mRNA

NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997

G

homeobox and leucine zipper encoding

decreases expression

fipronil results in decreased expression of HOMEZ mRNA

NCBI chr15:28,321,633...28,339,486
Ensembl chr15:28,320,819...28,339,745

G

hypoxanthine phosphoribosyltransferase 1

increases expression

fipronil results in increased expression of HPRT1 mRNA

NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154

G

HRas proto-oncogene, GTPase

decreases expression

fipronil results in decreased expression of HRAS mRNA

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

harakiri, BCL2 interacting protein

increases expression

fipronil results in increased expression of HRK mRNA

NCBI chr12:38,387,484...38,409,652

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid (17-beta) dehydrogenase 11

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of HSD17B11 mRNA
fipronil results in increased expression of HSD17B11 mRNA

NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161

G

hydroxysteroid (17-beta) dehydrogenase 12

decreases expression

fipronil results in decreased expression of HSD17B12 mRNA

NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617

G

hydroxysteroid (17-beta) dehydrogenase 13

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of HSD17B13 mRNA

NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166

G

hydroxysteroid (17-beta) dehydrogenase 14

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of HSD17B14 mRNA
fipronil results in increased expression of HSD17B14 mRNA

NCBI chr 1:96,029,224...96,039,577
Ensembl chr 1:96,029,284...96,039,883

G

hydroxysteroid (17-beta) dehydrogenase 2

decreases expression

fipronil results in decreased expression of HSD17B2 mRNA

NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of HSD17B3 mRNA
fipronil results in decreased expression of HSD17B3 mRNA

NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554

G

hydroxysteroid (17-beta) dehydrogenase 6

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of HSD17B6 mRNA
fipronil results in decreased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

hydroxysteroid (17-beta) dehydrogenase 7

increases expression

fipronil results in increased expression of HSD17B7 mRNA

NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression
multiple interactions

fipronil results in decreased expression of HSD3B1 mRNA
[fipronil co-treated with DEET] results in decreased expression of HSD3B1 mRNA

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

increases expression

fipronil results in increased expression of HSD3B7 mRNA

NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442

G

hydroxysteroid dehydrogenase like 1

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of HSDL1 mRNA
fipronil results in increased expression of HSDL1 mRNA

NCBI chr19:47,615,794...47,631,892
Ensembl chr19:47,615,796...47,631,846

G

heat shock transcription factor 1

decreases expression

fipronil results in decreased expression of HSF1 mRNA

NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011

G

HIV-1 Tat interactive protein 2

increases expression

fipronil results in increased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

5-hydroxytryptamine receptor 3A

increases expression
multiple interactions

fipronil results in increased expression of HTR3A mRNA
[fipronil co-treated with DEET] results in increased expression of HTR3A mRNA

NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389

G

HtrA serine peptidase 2

increases expression

fipronil results in increased expression of HTRA2 mRNA

NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095

G

HtrA serine peptidase 3

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of HTRA3 mRNA
fipronil results in increased expression of HTRA3 mRNA

NCBI chr14:75,068,917...75,097,315
Ensembl chr14:75,068,917...75,097,315

G

HtrA serine peptidase 4

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of HTRA4 mRNA

NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074

G

Huntingtin interacting protein K

decreases expression

fipronil results in decreased expression of HYPK mRNA

NCBI chr 3:108,434,997...108,436,370
Ensembl chr 3:108,432,539...108,436,370

G

intraflagellar transport 25

increases expression

fipronil results in increased expression of IFT25 mRNA

NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421

G

insulin-like growth factor 1

decreases expression
multiple interactions

fipronil results in decreased expression of IGF1 mRNA
[fipronil co-treated with DEET] results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 2 receptor

increases expression

fipronil results in increased expression of IGF2R mRNA

PMID:31881178 PMID:34044035

NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501

G

insulin-like growth factor binding protein 6

decreases expression

fipronil results in decreased expression of IGFBP6 mRNA

NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966

G

Indian hedgehog signaling molecule

decreases expression

fipronil results in decreased expression of IHH mRNA

NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532

G

interleukin 13 receptor subunit alpha 1

increases expression
decreases expression

fipronil results in increased expression of IL13RA1 mRNA
fipronil results in decreased expression of IL13RA1 mRNA

PMID:23962444 PMID:34044035

NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681

G

interleukin 17B

decreases expression

fipronil results in decreased expression of IL17B mRNA

NCBI chr18:55,141,194...55,145,565
Ensembl chr18:55,141,194...55,145,565

G

interleukin 1 receptor accessory protein

decreases expression

fipronil results in decreased expression of IL1RAP mRNA

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

G

IMP U3 small nucleolar ribonucleoprotein 3

decreases expression

fipronil results in decreased expression of IMP3 mRNA

NCBI chr 8:57,339,528...57,340,416
Ensembl chr 8:57,339,496...57,340,414

G

indolethylamine N-methyltransferase

increases expression

fipronil results in increased expression of INMT mRNA

NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493

G

inositol polyphosphate phosphatase-like 1

decreases expression

fipronil results in decreased expression of INPPL1 mRNA

NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500

G

insulin 2

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of INS mRNA
fipronil results in decreased expression of INS mRNA

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

G

insulin induced gene 2

increases expression

fipronil results in increased expression of INSIG2 mRNA

NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923

G

importin 5

increases expression

fipronil results in increased expression of IPO5 mRNA

NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126

G

IQ motif and ankyrin repeat containing 1

decreases expression
multiple interactions

fipronil results in decreased expression of IQANK1 mRNA
[fipronil co-treated with DEET] results in decreased expression of IQANK1 mRNA

NCBI chr 7:107,724,962...107,759,163
Ensembl chr 7:107,724,997...107,759,162

G

interferon regulatory factor 2 binding protein 2

increases expression

fipronil results in increased expression of IRF2BP2 mRNA

NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642

G

interferon regulatory factor 2 binding protein-like

increases expression

fipronil results in increased expression of IRF2BPL mRNA

NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401

G

isochorismatase domain containing 1

increases expression

fipronil results in increased expression of ISOC1 mRNA

NCBI chr18:52,158,790...52,179,206
Ensembl chr18:52,158,790...52,178,703

G

inositol-3-phosphate synthase 1

decreases expression

fipronil results in decreased expression of ISYNA1 mRNA

NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979

G

integrin subunit alpha 7

decreases expression

fipronil results in decreased expression of ITGA7 mRNA

NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450

G

integrin subunit beta 4

decreases expression

fipronil results in decreased expression of ITGB4 mRNA

NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012

G

inter-alpha-trypsin inhibitor heavy chain 2

increases expression

fipronil results in increased expression of ITIH2 mRNA

NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841

G

integral membrane protein 2B

increases expression

fipronil results in increased expression of ITM2B mRNA

NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917

G

inositol 1,4,5-trisphosphate receptor, type 3

increases expression

fipronil results in increased expression of ITPR3 mRNA

NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337

G

intersectin 1

increases expression

fipronil results in increased expression of ITSN1 mRNA

NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645

G

jagged canonical Notch ligand 2

increases expression

fipronil results in increased expression of JAG2 mRNA

NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818

G

junctional adhesion molecule 3

increases expression

fipronil results in increased expression of JAM3 mRNA

NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355

G

Jupiter microtubule associated homolog 2

decreases expression

fipronil results in decreased expression of JPT2 mRNA

NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170

G

KN motif and ankyrin repeat domains 2

increases expression

fipronil results in increased expression of KANK2 mRNA

NCBI chr 8:20,311,676...20,341,107
Ensembl chr 8:20,311,676...20,340,900

G

katanin catalytic subunit A1 like 1

decreases expression

fipronil results in decreased expression of KATNAL1 mRNA

NCBI chr12:6,094,663...6,156,114
Ensembl chr12:6,102,836...6,157,553

G

potassium voltage-gated channel subfamily B member 1

decreases expression

fipronil results in decreased expression of KCNB1 mRNA

NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194

G

potassium inwardly-rectifying channel, subfamily J, member 16

increases expression

fipronil results in increased expression of KCNJ16 mRNA

NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702

G

potassium two pore domain channel subfamily K member 2

decreases expression

fipronil results in decreased expression of KCNK2 mRNA

NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435

G

potassium channel tetramerization domain containing 6

decreases expression

fipronil results in decreased expression of KCTD6 mRNA

NCBI chr15:16,695,297...16,712,460
Ensembl chr15:16,695,297...16,698,699

G

lysine demethylase 4B

decreases expression

fipronil results in decreased expression of KDM4B mRNA

NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543

G

kinesin family member 20A

increases expression

fipronil results in increased expression of KIF20A mRNA

NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780

G

kinesin family member 22

increases expression

fipronil results in increased expression of KIF22 mRNA

NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401

G

kallikrein related-peptidase 14

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of KLK14 mRNA
fipronil results in decreased expression of KLK14 mRNA

NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240

G

kynurenine 3-monooxygenase

increases expression

fipronil results in increased expression of KMO mRNA

NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881

G

keratin 18

decreases expression

fipronil results in decreased expression of KRT18 mRNA

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

keratin 23

decreases expression

fipronil results in decreased expression of KRT23 mRNA

NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983

G

keratin 8

decreases expression

fipronil results in decreased expression of KRT8 mRNA

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

lactamase, beta 2

increases expression

fipronil results in increased expression of LACTB2 mRNA

NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429

G

laminin subunit alpha 5

increases expression

fipronil results in increased expression of LAMA5 mRNA

NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451

G

laminin subunit beta 1

increases expression

fipronil results in increased expression of LAMB1 mRNA

NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585

G

laminin subunit beta 3

decreases expression

fipronil results in decreased expression of LAMB3 mRNA

NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405

G

LanC like glutathione S-transferase 2

decreases expression

fipronil results in decreased expression of LANCL2 mRNA

NCBI chr 4:87,441,821...87,483,707
Ensembl chr 4:87,441,823...87,482,800

G

La ribonucleoprotein 1B

decreases expression

fipronil results in decreased expression of LARP1B mRNA

NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896

G

leukocyte cell-derived chemotaxin 2

decreases expression

fipronil results in decreased expression of LECT2 mRNA

NCBI chr17:8,044,759...8,050,983
Ensembl chr17:8,044,759...8,050,983

G

galectin 1

decreases expression

fipronil results in decreased expression of LGALS1 mRNA

NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345

G

LHFPL tetraspan subfamily member 2

increases expression

fipronil results in increased expression of LHFPL2 mRNA

NCBI chr 2:25,281,771...25,428,128
Ensembl chr 2:25,281,901...25,427,950

G

leukocyte immunoglobulin like receptor A5

decreases expression

fipronil results in decreased expression of LILRA5 mRNA

NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718

G

Lck interacting transmembrane adaptor 1

decreases expression

fipronil results in decreased expression of LIME1 mRNA

NCBI chr 3:168,490,535...168,496,627
Ensembl chr 3:168,490,074...168,493,127

G

LIM domain kinase 1

increases expression

fipronil results in increased expression of LIMK1 mRNA

NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606

G

lipase C, hepatic type

increases expression

fipronil results in increased expression of LIPC mRNA

NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464

G

LLGL scribble cell polarity complex component 2

decreases expression

fipronil results in decreased expression of LLGL2 mRNA

NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525

G

lectin, mannose-binding 2

increases expression

fipronil results in increased expression of LMAN2 mRNA

NCBI chr17:9,269,236...9,286,923
Ensembl chr17:9,269,022...9,287,265

G

lysyl oxidase-like 2

increases expression

fipronil results in increased expression of LOXL2 mRNA

NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067

G

leupaxin

decreases expression

fipronil results in decreased expression of LPXN mRNA

NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084

G

LDL receptor related protein 1

decreases expression
increases expression

fipronil results in decreased expression of LRP1 mRNA
fipronil results in increased expression of LRP1 mRNA

PMID:23962444 PMID:34044035

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

G

LDL receptor related protein 8

decreases expression

fipronil results in decreased expression of LRP8 mRNA

NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352

G

leucine rich repeat containing 20

decreases expression

fipronil results in decreased expression of LRRC20 mRNA

NCBI chr20:29,422,858...29,528,372
Ensembl chr20:29,422,925...29,528,369

G

leucine rich repeat containing 42

increases expression

fipronil results in increased expression of LRRC42 mRNA

NCBI chr 5:122,014,678...122,035,792
Ensembl chr 5:122,014,678...122,035,829

G

leucine rich repeat containing 51

increases expression

fipronil results in increased expression of LRRC51 mRNA

NCBI chr 1:156,278,617...156,297,838
Ensembl chr 1:156,278,618...156,297,773

G

leucine rich repeat containing 59

decreases expression

fipronil results in decreased expression of LRRC59 mRNA

NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533

G

leucine rich repeat containing 8 VRAC subunit D

decreases expression

fipronil results in decreased expression of LRRC8D mRNA

NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877

G

leucine rich repeat neuronal 3

increases expression

fipronil results in increased expression of LRRN3 mRNA

NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330

G

LSM1 homolog, mRNA degradation associated

decreases expression

fipronil results in decreased expression of LSM1 mRNA

NCBI chr16:66,277,345...66,288,852
Ensembl chr16:66,277,345...66,288,852

G

lanosterol synthase

increases expression

fipronil results in increased expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

leucine zipper tumor suppressor 2

increases expression

fipronil results in increased expression of LZTS2 mRNA

NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423

G

mono-ADP ribosylhydrolase 1

decreases expression

fipronil results in decreased expression of MACROD1 mRNA

NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716

G

mitotic arrest deficient 2 like 1

increases expression

fipronil results in increased expression of MAD2L1 mRNA

NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470

G

mal, T-cell differentiation protein 2

increases expression

fipronil results in increased expression of MAL2 mRNA

NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429

G

mannosidase, alpha, class 2A, member 1

decreases expression
increases expression

fipronil results in decreased expression of MAN2A1 mRNA
fipronil results in increased expression of MAN2A1 mRNA

PMID:23962444 PMID:31881178

NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349

G

mannosidase beta

increases expression

fipronil results in increased expression of MANBA mRNA

NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983

G

microtubule-associated protein 1B

increases expression

fipronil results in increased expression of MAP1B mRNA

NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317

G

mitogen activated protein kinase kinase 1

decreases activity

fipronil results in decreased activity of MAP2K1 protein

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

decreases activity
increases expression

fipronil results in decreased activity of MAP2K2 protein
fipronil results in increased expression of MAP2K2 mRNA

PMID:21167920 PMID:34044035

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase kinase 5

increases expression

fipronil results in increased expression of MAP2K5 mRNA

NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983

G

mitogen activated protein kinase 1

decreases activity

fipronil results in decreased activity of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases activity

fipronil results in decreased activity of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

MAPK activated protein kinase 2

decreases expression

fipronil results in decreased expression of MAPKAPK2 mRNA

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

G

membrane associated ring-CH-type finger 6

increases expression

fipronil results in increased expression of MARCHF6 mRNA

NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910

G

microtubule affinity regulating kinase 1

increases expression

fipronil results in increased expression of MARK1 mRNA

NCBI chr13:96,450,189...96,555,304
Ensembl chr13:96,451,487...96,555,173

G

MBL associated serine protease 1

increases expression

fipronil results in increased expression of MASP1 mRNA

NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974

G

MBL associated serine protease 2

decreases expression

fipronil results in decreased expression of MASP2 mRNA

NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580

G

methionine adenosyltransferase 2A

increases expression

fipronil results in increased expression of MAT2A mRNA

NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493

G

mannose binding lectin 1

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of MBL1P mRNA
fipronil results in decreased expression of MBL1P mRNA

NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174

G

mucolipin TRP cation channel 1

increases expression

fipronil results in increased expression of MCOLN1 mRNA

NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252

G

MDM2 proto-oncogene

increases expression

fipronil results in increased expression of MDM2 mRNA

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

malic enzyme 1

increases expression

fipronil results in increased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

mediator complex subunit 25

increases expression

fipronil results in increased expression of MED25 mRNA

NCBI chr 1:95,359,961...95,375,827
Ensembl chr 1:95,360,284...95,375,877

G

mediator complex subunit 4

decreases expression

fipronil results in decreased expression of MED4 mRNA

NCBI chr15:48,696,542...48,706,818
Ensembl chr15:48,696,511...48,706,820

G

maternally expressed 3

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of MEG3 mRNA
fipronil results in decreased expression of MEG3 mRNA

NCBI chr 6:128,491,808...128,524,010

G

multiple EGF-like-domains 11

decreases expression

fipronil results in decreased expression of MEGF11 mRNA

NCBI chr 8:64,892,312...65,218,984
Ensembl chr 8:64,892,387...65,216,061

G

Meis homeobox 3

increases expression

fipronil results in increased expression of MEIS3 mRNA

NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691

G

mesoderm specific transcript

increases expression

fipronil results in increased expression of MEST mRNA

NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145

G

methionyl aminopeptidase 1

increases expression

fipronil results in increased expression of METAP1 mRNA

NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434

G

matrix Gla protein

increases expression

fipronil results in increased expression of MGP mRNA

NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667

G

MIA SH3 domain ER export factor 2

increases expression

fipronil results in increased expression of MIA2 mRNA

NCBI chr 6:76,787,508...76,885,246
Ensembl chr 6:76,787,508...76,885,211

G

mitotic deacetylase associated SANT domain protein

increases expression

fipronil results in increased expression of MIDEAS mRNA

NCBI chr 6:103,784,779...103,854,470
Ensembl chr 6:103,787,873...103,829,178

G

migration and invasion inhibitory protein

increases expression

fipronil results in increased expression of MIIP mRNA

NCBI chr 5:158,292,510...158,299,533
Ensembl chr 5:158,292,511...158,299,694

G

makorin ring finger protein 1

increases expression

fipronil results in increased expression of MKRN1 mRNA

NCBI chr 4:68,175,908...68,197,216
Ensembl chr 4:68,175,909...68,197,165

G

melan-A

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of MLANA mRNA

NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343

G

malonyl-CoA decarboxylase

increases expression

fipronil results in increased expression of MLYCD mRNA

NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793

G

membrane metallo-endopeptidase

increases expression

fipronil results in increased expression of MME mRNA

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

meiotic nuclear divisions 1

increases expression

fipronil results in increased expression of MND1 mRNA

NCBI chr 2:169,433,523...169,496,081
Ensembl chr 2:169,433,540...169,496,096

G

MON1 homolog A, secretory trafficking associated

decreases expression

fipronil results in decreased expression of MON1A mRNA

NCBI chr 8:108,574,272...108,593,163
Ensembl chr 8:108,574,388...108,593,156

G

muscle RAS oncogene homolog

increases expression

fipronil results in increased expression of MRAS mRNA

NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408

G

mitochondrial ribosomal protein L12

decreases expression

fipronil results in decreased expression of MRPL12 mRNA

PMID:23962444 PMID:34044035

NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913

G

mitochondrial ribosomal protein L23

increases expression

fipronil results in increased expression of MRPL23 mRNA

NCBI chr 1:197,687,452...197,695,222
Ensembl chr 1:197,687,347...197,695,222

G

mitochondrial ribosomal protein S12

decreases expression

fipronil results in decreased expression of MRPS12 mRNA

NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780

G

mitochondrial ribosomal protein S21-like

decreases expression

fipronil results in decreased expression of MRPS21L mRNA

NCBI chr18:73,412,080...73,412,549
Ensembl chr18:73,412,141...73,412,443

G

mitochondrial ribosomal protein S34

decreases expression

fipronil results in decreased expression of MRPS34 mRNA

NCBI chr10:13,916,024...13,917,155
Ensembl chr10:13,916,026...13,918,406

G

male-specific lethal 3-like 2

increases expression
multiple interactions

fipronil results in increased expression of MSL3B mRNA
[fipronil co-treated with DEET] results in increased expression of MSL3B mRNA

NCBI chr20:35,468,877...35,477,025
Ensembl chr20:35,468,888...35,477,757

G

methionine sulfoxide reductase B1

increases expression

fipronil results in increased expression of MSRB1 mRNA

NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609

G

metallothionein 3

increases expression
multiple interactions

fipronil results in increased expression of MT3 mRNA
[fipronil co-treated with DEET] results in increased expression of MT3 mRNA

NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158

G

MDM2 binding protein

decreases expression

fipronil results in decreased expression of MTBP mRNA

NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827

G

mitochondrial ribosome-associated GTPase 1

increases expression

fipronil results in increased expression of MTG1 mRNA

NCBI chr 1:194,931,543...194,944,278
Ensembl chr 1:194,931,531...194,944,277

G

mitoregulin

multiple interactions

[fipronil co-treated with DEET] results in increased expression of MTLN mRNA

NCBI chr 3:115,018,810...115,019,668
Ensembl chr 3:115,019,473...115,019,643
Ensembl chr 3:115,019,473...115,019,643

G

myotubularin related protein 3

increases expression

fipronil results in increased expression of MTMR3 mRNA

NCBI chr14:79,340,523...79,460,947
Ensembl chr14:79,340,513...79,461,041

G

mitochondrial transcription rescue factor 1

increases expression

fipronil results in increased expression of MTRES1 mRNA

NCBI chr20:47,022,343...47,038,888
Ensembl chr20:47,022,342...47,038,805

G

mitochondrial translation release factor in rescue

increases expression

fipronil results in increased expression of MTRFR mRNA

NCBI chr12:32,261,569...32,275,258
Ensembl chr12:32,258,435...32,275,258

G

MYB proto-oncogene like 2

decreases expression

fipronil results in decreased expression of MYBL2 mRNA

PMID:23962444 PMID:34044035

NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708

G

MYC proto-oncogene, bHLH transcription factor

decreases expression

fipronil results in decreased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

Myc binding protein

decreases expression

fipronil results in decreased expression of MYCBP mRNA

NCBI chr 5:136,135,955...136,143,163
Ensembl chr 5:136,135,931...136,145,616

G

myosin heavy chain 14

increases expression

fipronil results in increased expression of MYH14 mRNA

NCBI chr 1:95,096,266...95,158,861
Ensembl chr 1:95,096,266...95,158,836

G

myosin, light chain 4

decreases expression

fipronil results in decreased expression of MYL4 mRNA

NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363

G

myosin light chain 6

decreases expression

fipronil results in decreased expression of MYL6 mRNA

NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791

G

myosin VIIA

increases expression

fipronil results in increased expression of MYO7A mRNA

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

G

NEDD4 binding protein 2-like 1

increases expression

fipronil results in increased expression of N4BP2L1 mRNA

NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257

G

N-acetylneuraminate synthase

decreases expression

fipronil results in decreased expression of NANS mRNA

NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950

G

nucleosome assembly protein 1-like 1

increases expression

fipronil results in increased expression of NAP1L1 mRNA

NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593

G

NSF attachment protein gamma

increases expression

fipronil results in increased expression of NAPG mRNA

NCBI chr18:56,439,620...56,459,159
Ensembl chr18:56,440,505...56,459,153

G

neural cell adhesion molecule 1

increases expression

fipronil results in increased expression of NCAM1 mRNA

NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014

G

non-SMC condensin II complex, subunit D3

decreases expression

fipronil results in decreased expression of NCAPD3 mRNA

NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373

G

nuclear cap binding protein subunit 2

decreases expression

fipronil results in decreased expression of NCBP2 mRNA

NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885

G

NCBP2 antisense 2 (head to head)

multiple interactions

[fipronil co-treated with DEET] results in increased expression of NCBP2AS2 mRNA

NCBI chr11:68,829,950...68,830,715
Ensembl chr11:68,829,983...68,830,708

G

nuclear receptor coactivator 5

decreases expression

fipronil results in decreased expression of NCOA5 mRNA

NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553

G

nuclear receptor co-repressor 2

decreases expression

fipronil results in decreased expression of NCOR2 mRNA

NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319

G

nicastrin

increases expression

fipronil results in increased expression of NCSTN mRNA

NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454

G

NADH:ubiquinone oxidoreductase complex assembly factor 1

increases expression

fipronil results in increased expression of NDUFAF1 mRNA

NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212

G

NADH:ubiquinone oxidoreductase core subunit S7

decreases expression

fipronil results in decreased expression of NDUFS7 mRNA

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

G

nectin cell adhesion molecule 2

increases expression

fipronil results in increased expression of NECTIN2 mRNA

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

G

neudesin neurotrophic factor

increases expression

fipronil results in increased expression of NENF mRNA

NCBI chr13:102,888,004...102,894,804
Ensembl chr13:102,888,004...102,894,804

G

neuroepithelial cell transforming 1

increases expression

fipronil results in increased expression of NET1 mRNA

NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441

G

neuralized E3 ubiquitin protein ligase 2

increases expression

fipronil results in increased expression of NEURL2 mRNA

NCBI chr 3:153,566,659...153,569,380
Ensembl chr 3:153,566,660...153,569,380

G

nuclear factor of activated T-cells 2 interacting protein

decreases expression

fipronil results in decreased expression of NFATC2IP mRNA

NCBI chr 1:180,954,834...180,971,847
Ensembl chr 1:180,955,043...180,971,747

G

nuclear factor, erythroid 2

increases expression

fipronil results in increased expression of NFE2 mRNA

NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108

G

nuclear factor I X

decreases expression

fipronil results in decreased expression of NFIX mRNA

NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265

G

NFKB inhibitor zeta

decreases expression

fipronil results in decreased expression of NFKBIZ mRNA

NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723

G

NFS1 cysteine desulfurase

decreases expression

fipronil results in decreased expression of NFS1 mRNA

NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666

G

nicolin 1, tubulin polyglutamylase complex subunit

increases expression

fipronil results in increased expression of NICN1 mRNA

NCBI chr 8:108,976,393...108,981,620
Ensembl chr 8:108,976,464...108,981,067

G

ninjurin 2

decreases expression

fipronil results in decreased expression of NINJ2 mRNA

NCBI chr 4:153,306,439...153,408,618
Ensembl chr 4:153,306,553...153,408,617

G

nucleolar pre-rRNA processing protein NIP7

decreases expression

fipronil results in decreased expression of NIP7 mRNA

NCBI chr19:34,962,557...34,964,700
Ensembl chr19:34,962,557...34,964,711

G

nipsnap homolog 1

increases expression

fipronil results in increased expression of NIPSNAP1 mRNA

NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098

G

neurolysin

decreases expression

fipronil results in decreased expression of NLN mRNA

NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914

G

nicotinamide nucleotide adenylyltransferase 3

decreases expression

fipronil results in decreased expression of NMNAT3 mRNA

NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645

G

nucleolar and coiled-body phosphoprotein 1

decreases expression

fipronil results in decreased expression of NOLC1 mRNA

NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088

G

NOP53 ribosome biogenesis factor

increases expression

fipronil results in increased expression of NOP53 mRNA

NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902

G

NOP protein chaperone 1

decreases expression

fipronil results in decreased expression of NOPCHAP1 mRNA

NCBI chr 7:20,353,626...20,359,685
Ensembl chr 7:20,353,634...20,359,690

G

nitric oxide synthase 2

increases expression

fipronil results in increased expression of NOS2 protein

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

increases expression

fipronil results in increased expression of NOS3 mRNA

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

nitric oxide synthase trafficking

increases expression

fipronil results in increased expression of NOSTRIN mRNA

NCBI chr 3:53,904,746...53,970,995
Ensembl chr 3:53,904,827...53,970,988

G

NPC intracellular cholesterol transporter 1

decreases expression

fipronil results in decreased expression of NPC1 mRNA

NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049

G

nephrocystin 1

increases expression

fipronil results in increased expression of NPHP1 mRNA

NCBI chr 3:114,960,650...115,016,234
Ensembl chr 3:114,960,650...115,016,234

G

nucleophosmin/nucleoplasmin, 3

decreases expression

fipronil results in decreased expression of NPM3 mRNA

NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591

G

neuropeptide W

increases expression

fipronil results in increased expression of NPW mRNA

NCBI chr10:13,680,275...13,681,618
Ensembl chr10:13,680,321...13,681,586

G

NAD(P)H quinone dehydrogenase 1

increases expression

fipronil results in increased expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 0, group B, member 2

multiple interactions

[fipronil co-treated with DEET] results in increased expression of NR0B2 mRNA

NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609

G

nuclear receptor subfamily 1, group I, member 2

increases activity
multiple interactions
decreases expression

fipronil results in increased activity of NR1I2 protein
NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of ABCC3 mRNA]; NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of CES2A mRNA]; NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of CYP3A11 mRNA]; NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of GSTA2 mRNA]; NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of SLCO1A4 mRNA]
fipronil results in decreased expression of NR1I2 mRNA

PMID:16565514 PMID:20143881 PMID:23962444 PMID:27091632 PMID:28728110

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor subfamily 1, group I, member 3

multiple interactions
affects expression

NR1I3 gene mutant form inhibits the reaction [fipronil results in increased expression of CYP2B10 mRNA]; NR1I3 gene mutant form inhibits the reaction [fipronil results in increased expression of GSTA2 mRNA]
fipronil affects the expression of NR1I3 mRNA

PMID:23962444 PMID:38050659

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

nuclear receptor subfamily 3, group C, member 2

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of NR3C2 mRNA; fipronil inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]

PMID:27091632 PMID:29149346

NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885

G

neuronal regeneration related protein

increases expression

fipronil results in increased expression of NREP mRNA

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

neuregulin 2

increases expression

fipronil results in increased expression of NRG2 mRNA

NCBI chr18:27,616,542...27,798,505
Ensembl chr18:27,619,661...27,798,505

G

nuclear receptor interacting protein 3

increases expression

fipronil results in increased expression of NRIP3 mRNA

NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600

G

nuclear receptor binding SET domain protein 2

increases expression

fipronil results in increased expression of NSD2 mRNA

NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641

G

neutral sphingomyelinase activation associated factor

decreases expression

fipronil results in decreased expression of NSMAF mRNA

NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627

G

NMDA receptor synaptonuclear signaling and neuronal migration factor

increases expression

fipronil results in increased expression of NSMF mRNA

NCBI chr 3:7,861,846...7,870,615
Ensembl chr 3:7,861,872...7,870,614

G

5'-nucleotidase, cytosolic IB

decreases expression

fipronil results in decreased expression of NT5C1B mRNA

NCBI chr 6:33,139,053...33,156,489
Ensembl chr 6:33,139,064...33,156,481

G

5'-nucleotidase, cytosolic IIIA

increases expression

fipronil results in increased expression of NT5C3 mRNA

NCBI chr 4:86,161,642...86,204,656
Ensembl chr 4:86,161,643...86,204,628

G

5'-nucleotidase domain containing 1

increases expression

fipronil results in increased expression of NT5DC1 mRNA

NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591

G

5'-nucleotidase domain containing 2

decreases expression

fipronil results in decreased expression of NT5DC2 mRNA

PMID:23962444 PMID:34044035

NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537

G

neurotrophic receptor tyrosine kinase 2

decreases expression

fipronil results in decreased expression of NTRK2 mRNA

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

G

nucleobindin 2

increases expression

fipronil results in increased expression of NUCB2 mRNA

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

nuclear casein kinase and cyclin-dependent kinase substrate 1

decreases expression

fipronil results in decreased expression of NUCKS1 mRNA

NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229

G

nudix hydrolase 2

increases expression

fipronil results in increased expression of NUDT2 mRNA

NCBI chr 5:56,628,265...56,643,104
Ensembl chr 5:56,628,265...56,643,104

G

nudix hydrolase 7

decreases expression

fipronil results in decreased expression of NUDT7 mRNA

NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081

G

nudix hydrolase 8

decreases expression

fipronil results in decreased expression of NUDT8 mRNA

NCBI chr 1:201,293,660...201,295,233
Ensembl chr 1:201,292,619...201,295,224

G

nuclear mitotic apparatus protein 1

decreases expression

fipronil results in decreased expression of NUMA1 mRNA

NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855

G

nucleoporin 210

increases expression

fipronil results in increased expression of NUP210 mRNA

NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874

G

nucleoporin 50, pseudogene 1

increases expression

fipronil results in increased expression of SPG7 mRNA

NCBI chr 4:128,787,567...128,789,296
Ensembl chr 4:128,787,100...128,789,312

G

nucleoporin 54

increases expression

fipronil results in increased expression of NUP54 mRNA

NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028

G

out at first homolog

decreases expression

fipronil results in decreased expression of OAF mRNA

NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334

G

ornithine aminotransferase

increases expression

fipronil results in increased expression of OAT mRNA

NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682

G

ornithine decarboxylase antizyme 1

decreases expression

fipronil results in decreased expression of OAZ1 mRNA

NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310

G

OCIA domain containing 1

increases expression

fipronil results in increased expression of OCIAD1 mRNA

NCBI chr14:34,897,851...34,915,291
Ensembl chr14:34,897,847...34,915,286

G

oxoglutarate dehydrogenase

increases expression

fipronil results in increased expression of OGDH mRNA

NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479

G

olfactomedin-like 3

increases expression

fipronil results in increased expression of OLFML3 mRNA

NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050

G

olfactory receptor family 8 subfamily B member 46C

decreases expression

fipronil results in decreased expression of OR8B46C mRNA

NCBI chr 8:38,662,256...38,663,176

G

origin recognition complex, subunit 3

increases expression

fipronil results in increased expression of ORC3 mRNA

NCBI chr 5:49,123,758...49,181,552
Ensembl chr 5:49,126,955...49,181,633

G

oxysterol binding protein-like 1A

decreases expression
increases expression

fipronil results in decreased expression of OSBPL1A mRNA
fipronil results in increased expression of OSBPL1A mRNA

PMID:23962444 PMID:34044035

NCBI chr18:3,904,006...4,094,635
Ensembl chr18:3,904,006...4,094,585

G

oxysterol binding protein-like 6

increases expression

fipronil results in increased expression of OSBPL6 mRNA

NCBI chr 3:61,343,776...61,541,170
Ensembl chr 3:61,343,809...61,537,102

G

oxysterol binding protein-like 7

increases expression

fipronil results in increased expression of OSBPL7 mRNA

NCBI chr10:82,035,995...82,053,566
Ensembl chr10:82,036,042...82,053,557

G

osteoclastogenesis associated transmembrane protein 1

increases expression

fipronil results in increased expression of OSTM1 mRNA

NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023

G

phosphofurin acidic cluster sorting protein 1

increases expression

fipronil results in increased expression of PACS1 mRNA

NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 2

decreases expression

fipronil results in decreased expression of PAFAH1B2 mRNA

NCBI chr 8:46,260,069...46,312,073
Ensembl chr 8:46,261,064...46,279,833

G

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3

decreases expression

fipronil results in decreased expression of PAFAH1B3 mRNA

NCBI chr 1:80,881,263...80,883,789
Ensembl chr 1:80,881,309...80,883,893

G

paralemmin A kinase anchor protein

increases expression

fipronil results in increased expression of PAKAP mRNA

NCBI chr 5:72,536,986...72,648,524
NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524

G

peptidylglycine alpha-amidating monooxygenase

increases expression

fipronil results in increased expression of PAM mRNA

NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965

G

pantothenate kinase 2

increases expression

fipronil results in increased expression of PANK2 mRNA

NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320

G

pannexin 2

increases expression

fipronil results in increased expression of PANX2 mRNA

PMID:23962444 PMID:31881178

NCBI chr 7:120,139,259...120,153,056
Ensembl chr 7:120,139,294...120,152,361

G

progestin and adipoQ receptor family member 3

decreases expression

fipronil results in decreased expression of PAQR3 mRNA

NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994

G

progestin and adipoQ receptor family member 4

decreases expression

fipronil results in decreased expression of PAQR4 mRNA

NCBI chr10:12,758,970...12,762,649
Ensembl chr10:12,758,972...12,762,584

G

progestin and adipoQ receptor family member 9

decreases expression

fipronil results in decreased expression of PAQR9 mRNA

NCBI chr 8:96,114,249...96,116,546

G

pyruvate carboxylase

decreases expression

fipronil results in decreased expression of PC mRNA

NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380

G

protocadherin 18

decreases expression

fipronil results in decreased expression of PCDH18 mRNA

NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

fipronil results in increased expression of PCK2 mRNA

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

G

proliferating cell nuclear antigen

increases expression

fipronil results in increased expression of PCNA mRNA

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

Purkinje cell protein 2

decreases expression

fipronil results in decreased expression of PCP2 mRNA

NCBI chr12:1,681,659...1,683,899
Ensembl chr12:1,681,659...1,683,899

G

proprotein convertase subtilisin/kexin type 4

increases expression

fipronil results in increased expression of PCSK4 mRNA

NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585

G

phosphatidylcholine transfer protein

decreases expression

fipronil results in decreased expression of PCTP mRNA

NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867

G

programmed cell death 6

decreases expression

fipronil results in decreased expression of PDCD6 mRNA

NCBI chr 1:28,966,518...28,982,188
Ensembl chr 1:28,966,518...28,982,189

G

programmed cell death 7

decreases expression

fipronil results in decreased expression of PDCD7 mRNA

NCBI chr 8:65,862,606...65,877,333
Ensembl chr 8:65,862,387...65,877,333

G

phosphodiesterase 2A

increases expression

fipronil results in increased expression of PDE2A mRNA

NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434

G

phosphodiesterase 4B

decreases expression

fipronil results in decreased expression of PDE4B mRNA

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

peptide deformylase (mitochondrial)

increases expression

fipronil results in increased expression of PDF mRNA

NCBI chr19:34,949,408...34,951,621
Ensembl chr19:34,948,256...34,951,515

G

pyruvate dehydrogenase kinase 1

decreases expression

fipronil results in decreased expression of PDK1 mRNA

NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038

G

pyridoxal phosphatase

decreases expression

fipronil results in decreased expression of PDXP mRNA

NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963

G

pseudopodium-enriched atypical kinase 1

increases expression

fipronil results in increased expression of PEAK1 mRNA

NCBI chr 8:56,605,040...56,819,748
Ensembl chr 8:56,609,015...56,819,096

G

penta-EF hand domain containing 1

increases expression

fipronil results in increased expression of PEF1 mRNA

NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067

G

peroxisomal biogenesis factor 19

decreases expression

fipronil results in decreased expression of PEX19 mRNA

NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608

G

peroxisomal biogenesis factor 3

decreases expression

fipronil results in decreased expression of PEX3 mRNA

NCBI chr 1:7,912,508...7,954,474
Ensembl chr 1:7,912,506...7,954,518

G

peroxisomal biogenesis factor 7

increases expression

fipronil results in increased expression of PEX7 mRNA

NCBI chr 1:14,582,698...14,646,686
Ensembl chr 1:14,582,699...14,646,748

G

prefoldin subunit 5

decreases expression

fipronil results in decreased expression of PFDN5 mRNA

NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516

G

phosphoglycerate mutase 1

decreases expression

fipronil results in decreased expression of PGAM1 mRNA

NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452

G

post-GPI attachment to proteins phospholipase 3

decreases expression

fipronil results in decreased expression of PGAP3 mRNA

NCBI chr10:83,387,113...83,399,357
Ensembl chr10:83,387,113...83,398,628

G

phosphoglucomutase 2

increases expression

fipronil results in increased expression of PGM2 mRNA

NCBI chr14:44,166,314...44,199,828
Ensembl chr14:44,164,425...44,199,967

G

progesterone receptor membrane component 1

increases expression

fipronil results in increased expression of PGRMC1 mRNA

NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682

G

progesterone receptor membrane component 2

decreases expression

fipronil results in decreased expression of PGRMC2 mRNA

NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155

G

PHD finger protein 20

decreases expression

fipronil results in decreased expression of PHF20 mRNA

NCBI chr 3:144,710,253...144,816,696
Ensembl chr 3:144,710,353...144,814,439

G

PHD finger protein 20-like 1

increases expression

fipronil results in increased expression of PHF20L1 mRNA

NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526

G

PHD finger protein 5A

decreases expression

fipronil results in decreased expression of PHF5A mRNA

NCBI chr 7:113,378,469...113,385,035
Ensembl chr 7:113,378,471...113,385,460

G

pleckstrin homology-like domain, family B, member 1

decreases expression

fipronil results in decreased expression of PHLDB1 mRNA

NCBI chr 8:45,003,543...45,051,541
Ensembl chr 8:45,003,538...45,051,522

G

putative homeodomain transcription factor 1

increases expression

fipronil results in increased expression of PHTF1 mRNA

NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078

G

phosphoinositide-3-kinase regulatory subunit 3

increases expression

fipronil results in increased expression of PIK3R3 mRNA

NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583

G

pirin

increases expression

fipronil results in increased expression of PIR mRNA

PMID:23962444 PMID:31881178

NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218

G

phosphatidylinositol transfer protein, membrane-associated 1

increases expression

fipronil results in increased expression of PITPNM1 mRNA

NCBI chr 1:201,394,099...201,407,523
Ensembl chr 1:201,394,149...201,407,522

G

plakophilin 1

increases expression

fipronil results in increased expression of PKP1 mRNA

NCBI chr13:47,309,607...47,357,432
Ensembl chr13:47,309,614...47,357,465

G

phospholipase A2, group IIE

decreases expression

fipronil results in decreased expression of PLA2G2E mRNA

NCBI chr 5:151,121,363...151,127,147
Ensembl chr 5:151,121,439...151,126,821

G

phospholipase C beta 1

increases expression

fipronil results in increased expression of PLCB1 mRNA

NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869

G

phospholipase D family, member 3

decreases expression

fipronil results in decreased expression of PLD3 mRNA

NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072

G

pleckstrin homology domain containing A5

increases expression

fipronil results in increased expression of PLEKHA5 mRNA

NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546

G

pleckstrin homology and RhoGEF domain containing G3

decreases expression

fipronil results in decreased expression of PLEKHG3 mRNA

NCBI chr 6:95,265,756...95,308,952
Ensembl chr 6:95,266,058...95,310,359

G

polo-like kinase 3

increases expression

fipronil results in increased expression of PLK3 mRNA

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

phospholipid phosphatase 1

increases expression

fipronil results in increased expression of PLPP1 mRNA

NCBI chr 2:44,439,002...44,500,430
Ensembl chr 2:44,438,994...44,501,268

G

phospholipid phosphatase 3

decreases expression
increases expression

fipronil results in decreased expression of PLPP3 mRNA
fipronil results in increased expression of PLPP3 mRNA

PMID:23962444 PMID:31881178

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

G

phospholipid scramblase 2

decreases expression

fipronil results in decreased expression of PLSCR2 mRNA

NCBI chr 8:92,809,422...92,845,947
Ensembl chr 8:92,808,398...92,845,932

G

pregnancy up-regulated nonubiquitous CaM kinase

decreases expression

fipronil results in decreased expression of PNCK mRNA

NCBI chr X:151,369,406...151,373,508
Ensembl chr X:151,369,410...151,373,446

G

patatin-like phospholipase domain containing 5

decreases expression

fipronil results in decreased expression of PNPLA5 mRNA

NCBI chr 7:115,246,050...115,257,039
Ensembl chr 7:115,246,050...115,257,039

G

DNA polymerase epsilon 3, accessory subunit

decreases expression

fipronil results in decreased expression of POLE3 mRNA

NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
Ensembl chr 7:75,974,717...75,977,231

G

DNA polymerase gamma, catalytic subunit

increases expression

fipronil results in increased expression of POLG mRNA

NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567

G

RNA polymerase I subunit A

decreases expression

fipronil results in decreased expression of POLR1A mRNA

NCBI chr 4:103,950,051...104,014,022
Ensembl chr 4:103,950,051...104,014,020

G

protein-O-mannosyltransferase 2

decreases expression

fipronil results in decreased expression of POMT2 mRNA

NCBI chr 6:106,755,462...106,794,849
Ensembl chr 6:106,755,462...106,794,849

G

cytochrome p450 oxidoreductase

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of POR mRNA
fipronil results in increased expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

porcupine O-acyltransferase

increases expression

fipronil results in increased expression of PORCN mRNA

NCBI chr X:14,285,864...14,298,481
Ensembl chr X:14,285,871...14,298,481

G

POU class 2 homeobox associating factor 1

decreases expression

fipronil results in decreased expression of POU2AF1 mRNA

NCBI chr 8:51,521,813...51,548,819
Ensembl chr 8:51,474,015...51,548,819

G

peroxisome proliferator activated receptor alpha

affects expression

fipronil affects the expression of PPARA mRNA

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

increases expression

fipronil results in increased expression of PPARG mRNA; fipronil results in increased expression of PPARG protein

PMID:27103584 PMID:38050659

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PTPRF interacting protein alpha 1

increases expression

fipronil results in increased expression of PPFIA1 mRNA

NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277

G

PPFIA binding protein 2

increases expression

fipronil results in increased expression of PPFIBP2 mRNA

NCBI chr 1:161,504,774...161,687,339
Ensembl chr 1:161,504,890...161,655,212

G

peptidylprolyl isomerase A

decreases expression

fipronil results in decreased expression of PPIA mRNA

NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601

G

peptidylprolyl isomerase like 3

decreases expression

fipronil results in decreased expression of PPIL3 mRNA

NCBI chr 9:59,966,405...59,980,147
Ensembl chr 9:59,964,919...59,979,886

G

protein phosphatase 1, regulatory subunit 12C

decreases expression

fipronil results in decreased expression of PPP1R12C mRNA

NCBI chr 1:69,320,240...69,343,200
Ensembl chr 1:69,320,255...69,343,200

G

protein phosphatase 1, regulatory (inhibitor) subunit 14B

increases expression
decreases expression

fipronil results in increased expression of PPP1R14B mRNA
fipronil results in decreased expression of PPP1R14B mRNA

PMID:31881178 PMID:34044035

NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319

G

protein phosphatase 2 scaffold subunit A beta

decreases expression

fipronil results in decreased expression of PPP2R1B mRNA

NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485

G

protein phosphatase 2, regulatory subunit B'', gamma

increases expression

fipronil results in increased expression of PPP2R3C mRNA

NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491

G

protein phosphatase 6, regulatory subunit 3

decreases expression

fipronil results in decreased expression of PPP6R3 mRNA

NCBI chr 1:200,693,128...200,807,578
Ensembl chr 1:200,693,440...200,807,548

G

protease-associated domain containing 1

decreases expression

fipronil results in decreased expression of PRADC1 mRNA

NCBI chr 4:117,984,732...117,989,710
Ensembl chr 4:117,984,742...117,989,886

G

PRAME family member 8

multiple interactions
increases expression

[fipronil co-treated with DEET] results in increased expression of PRAMEF8 mRNA
fipronil results in increased expression of PRAMEF8 mRNA

NCBI chr 5:155,778,156...155,793,935
Ensembl chr 5:155,778,201...155,793,932

G

peroxiredoxin 1

increases expression
decreases expression

fipronil results in increased expression of PRDX1 mRNA
fipronil results in decreased expression of PRDX1 mRNA

PMID:23962444 PMID:34044035

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

prickle planar cell polarity protein 3

decreases expression

fipronil results in decreased expression of PRICKLE3 mRNA

NCBI chr X:14,837,647...14,849,305
Ensembl chr X:14,837,650...14,848,218

G

protein kinase cAMP-activated catalytic subunit beta

increases expression

fipronil results in increased expression of PRKACB mRNA

NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198

G

protein kinase cAMP-dependent type I regulatory subunit beta

decreases expression

fipronil results in decreased expression of PRKAR1B mRNA

NCBI chr12:15,492,233...15,624,942
Ensembl chr12:15,511,801...15,624,942

G

protein kinase D2

decreases expression

fipronil results in decreased expression of PRKD2 mRNA

NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376

G

protein kinase D3

increases expression

fipronil results in increased expression of PRKD3 mRNA

NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443

G

protein activator of interferon induced protein kinase EIF2AK2

increases expression

fipronil results in increased expression of PRKRA mRNA

NCBI chr 3:61,575,447...61,594,393
Ensembl chr 3:61,575,447...61,594,347

G

protein arginine methyltransferase 1

decreases expression

fipronil results in decreased expression of PRMT1 mRNA

NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345

G

prolyl-tRNA synthetase associated domain containing 1

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of PRORSD1P mRNA

NCBI chr14:103,257,979...103,260,248
Ensembl chr14:103,257,979...103,260,248

G

protein S

increases expression

fipronil results in increased expression of PROS1 mRNA

NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286

G

proline and serine rich 2

increases expression

fipronil results in increased expression of PROSER2 mRNA

NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825

G

pre-mRNA processing factor 3

decreases expression

fipronil results in decreased expression of PRPF3 mRNA

NCBI chr 2:183,379,041...183,403,526
Ensembl chr 2:183,378,718...183,403,489

G

proline-rich coiled-coil 1

increases expression

fipronil results in increased expression of PRRC1 mRNA

NCBI chr18:50,812,548...50,846,273
Ensembl chr18:50,812,552...50,849,476

G

phosphoribosyl transferase domain containing 1

increases expression

fipronil results in increased expression of PRTFDC1 mRNA

NCBI chr17:83,549,608...83,654,517
Ensembl chr17:83,548,803...83,655,179

G

proteasome 20S subunit alpha 1

increases expression
decreases expression

fipronil results in increased expression of PSMA1 mRNA
fipronil results in decreased expression of PSMA1 mRNA

PMID:23962444 PMID:34044035

NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472

G

proteasome 20S subunit alpha 5

decreases expression

fipronil results in decreased expression of PSMA5 mRNA

NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731

G

proteasome 20S subunit alpha 7

decreases expression

fipronil results in decreased expression of PSMA7 mRNA

NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672

G

proteasome 20S subunit beta 10

decreases expression

fipronil results in decreased expression of PSMB10 mRNA

NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626

G

proteasome 20S subunit beta 2

decreases expression

fipronil results in decreased expression of PSMB2 mRNA

NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137

G

proteasome 20S subunit beta 3

decreases expression

fipronil results in decreased expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 26S subunit, ATPase 6

increases expression

fipronil results in increased expression of PSMC6 mRNA

NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055

G

proteasome 26S subunit, non-ATPase 1

increases expression

fipronil results in increased expression of PSMD1 mRNA

NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211

G

prostaglandin reductase 1

increases expression

fipronil results in increased expression of PTGR1 mRNA

NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666

G

prostaglandin-endoperoxide synthase 1

increases expression

fipronil results in increased expression of PTGS1 mRNA

NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586

G

parathyroid hormone 2 receptor

increases expression

fipronil results in increased expression of PTH2R mRNA

NCBI chr 9:66,706,050...66,810,601
Ensembl chr 9:66,706,050...66,810,036

G

prothymosin alpha

decreases expression

fipronil results in decreased expression of PTMA mRNA

NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333

G

protein tyrosine phosphatase 4A1

increases expression
decreases expression

fipronil results in increased expression of PTP4A1 mRNA
fipronil results in decreased expression of PTP4A1 mRNA

PMID:23962444 PMID:34044035

NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964

G

protein tyrosine phosphatase, receptor type, A

increases expression

fipronil results in increased expression of PTPRA mRNA

PMID:23962444 PMID:34044035

NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728

G

protein tyrosine phosphatase, receptor type, F

increases expression

fipronil results in increased expression of PTPRF mRNA

NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023

G

protein tyrosine phosphatase, receptor type, N

increases expression

fipronil results in increased expression of PTPRN mRNA

NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190

G

peptidyl-tRNA hydrolase domain containing 1

decreases expression

fipronil results in decreased expression of PTRHD1 mRNA

NCBI chr 6:27,218,417...27,221,805
Ensembl chr 6:27,218,417...27,221,805

G

pseudouridine synthase like 1

increases expression

fipronil results in increased expression of PUSL1 mRNA

NCBI chr 5:166,497,643...166,500,647
Ensembl chr 5:166,496,755...166,500,611

G

parvalbumin

decreases expression

fipronil results in decreased expression of PVALB mRNA

NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561

G

Pvt1 oncogene

decreases expression

fipronil results in decreased expression of PVT1 mRNA

NCBI chr 7:93,656,528...93,879,938

G

PWWP domain containing 2B

increases expression

fipronil results in increased expression of PWWP2B mRNA

NCBI chr 1:194,040,395...194,059,979
Ensembl chr 1:194,041,341...194,059,958

G

glutaminyl-tRNA synthetase 1

increases expression

fipronil results in increased expression of QARS1 mRNA

NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739

G

Q-nucleotide N-glycosylase 1

increases expression

fipronil results in increased expression of QNG1 mRNA

NCBI chr17:6,281,377...6,288,976
Ensembl chr17:6,281,400...6,288,975

G

quiescin sulfhydryl oxidase 1

decreases expression

fipronil results in decreased expression of QSOX1 mRNA

NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459

G

RAB11a, member RAS oncogene family

increases expression

fipronil results in increased expression of RAB11A mRNA

PMID:23962444 PMID:31881178

NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525

G

RAB36, member RAS oncogene family

decreases expression

fipronil results in decreased expression of RAB36 mRNA

NCBI chr20:13,606,700...13,624,304
Ensembl chr20:13,608,136...13,624,170

G

RAB6B, member RAS oncogene family

increases expression

fipronil results in increased expression of RAB6B mRNA

NCBI chr 8:103,695,328...103,764,023
Ensembl chr 8:103,695,631...103,805,732

G

ral guanine nucleotide dissociation stimulator like 1

increases expression

fipronil results in increased expression of RGL1 mRNA

NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191

G

RAP1B, member of RAS oncogene family

decreases expression

fipronil results in decreased expression of RAP1B mRNA

NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370

G

RASD family, member 2

decreases expression

fipronil results in decreased expression of RASD2 mRNA

NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016

G

RAS protein-specific guanine nucleotide-releasing factor 1

increases expression

fipronil results in increased expression of RASGRF1 mRNA

NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269

G

Ras association domain family member 7

decreases expression

fipronil results in decreased expression of RASSF7 mRNA

NCBI chr 1:196,319,600...196,323,787
Ensembl chr 1:196,320,902...196,323,770

G

RNA binding motif protein 38

increases expression

fipronil results in increased expression of RBM38 mRNA

NCBI chr 3:161,801,577...161,814,381
Ensembl chr 3:161,801,577...161,814,381

G

Rbmx like 1

decreases expression

fipronil results in decreased expression of RBMXL1 mRNA

NCBI chr19:29,407,902...29,411,519
Ensembl chr19:29,407,912...29,412,859

G

ring-box 1

decreases expression

fipronil results in decreased expression of RBX1 mRNA

NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051

G

RCAN family member 3

increases expression

fipronil results in increased expression of RCAN3 mRNA

NCBI chr 5:147,650,935...147,671,881
Ensembl chr 5:147,655,085...147,671,937

G

RCC1 and BTB domain containing protein 2

increases expression

fipronil results in increased expression of RCBTB2 mRNA

NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750

G

ring finger and CHY zinc finger domain containing 1

increases expression
multiple interactions

fipronil results in increased expression of RCHY1 mRNA
[fipronil co-treated with DEET] results in increased expression of RCHY1 mRNA

NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167

G

retinol dehydrogenase 10

increases expression

fipronil results in increased expression of RDH10 mRNA

NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572

G

RELT-like 1

increases expression

fipronil results in increased expression of RELL1 mRNA

NCBI chr14:44,318,640...44,378,541
Ensembl chr14:44,303,009...44,378,500

G

RELT-like 2

increases expression

fipronil results in increased expression of RELL2 mRNA

NCBI chr18:29,789,996...29,793,986
Ensembl chr18:29,790,415...29,793,986

G

arginine-glutamic acid dipeptide repeats

increases expression

fipronil results in increased expression of RERE mRNA

NCBI chr 5:160,765,855...161,097,678
Ensembl chr 5:160,765,934...161,097,677

G

regulated endocrine-specific protein 18

decreases expression

fipronil results in decreased expression of RESP18 mRNA

NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722

G

RNA exonuclease 1 homolog

decreases expression

fipronil results in decreased expression of REXO1 mRNA

NCBI chr 7:9,154,050...9,174,035
Ensembl chr 7:9,154,061...9,173,454

G

regulator of G-protein signaling 5

increases expression

fipronil results in increased expression of RGS5 mRNA

PMID:23962444 PMID:31881178

NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518

G

ras homolog family member A

increases expression

fipronil results in increased expression of RHOA mRNA

NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746

G

ras homolog family member B

decreases expression

fipronil results in decreased expression of RHOB mRNA

NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108

G

ras homolog family member Q

increases expression

fipronil results in increased expression of RHOQ mRNA

NCBI chr 6:7,613,632...7,652,047

G

Rhox homeobox family member 2B

decreases expression

fipronil results in decreased expression of RHOXF2B mRNA

NCBI chr X:116,507,488...116,514,240
Ensembl chr X:116,507,488...116,513,870

G

RIO kinase 3

decreases expression

fipronil results in decreased expression of RIOK3 mRNA

NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343

G

receptor-interacting serine-threonine kinase 2

decreases expression

fipronil results in decreased expression of RIPK2 mRNA

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

G

RHO family interacting cell polarization regulator 2

increases expression

fipronil results in increased expression of RIPOR2 mRNA

NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092

G

ripply transcriptional repressor 3

increases expression

fipronil results in increased expression of RIPPLY3 mRNA

NCBI chr11:33,648,471...33,656,587
Ensembl chr11:33,648,486...33,656,584

G

5.8S ribosomal RNA

increases expression

fipronil results in increased expression of RN5-8S mRNA

G

ring finger protein 103

increases expression

fipronil results in increased expression of RNF103 mRNA

NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919

G

ring finger protein 150

decreases expression

fipronil results in decreased expression of RNF150 mRNA

NCBI chr19:25,006,978...25,229,273
Ensembl chr19:25,006,611...25,228,678

G

ring finger protein 170

increases expression

fipronil results in increased expression of RNF170 mRNA

NCBI chr16:65,928,886...65,954,092
Ensembl chr16:65,928,895...65,954,083

G

ring finger protein 182

decreases expression

fipronil results in decreased expression of RNF182 mRNA

NCBI chr17:21,026,110...21,081,760
Ensembl chr17:21,030,214...21,094,911

G

ring finger protein 216

decreases expression

fipronil results in decreased expression of RNF216 mRNA

NCBI chr12:11,454,752...11,576,305
Ensembl chr12:11,454,797...11,576,304

G

roundabout guidance receptor 2

increases expression

fipronil results in increased expression of ROBO2 mRNA

NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536

G

ribosomal protein L13A

increases expression

fipronil results in increased expression of RPL13A mRNA

NCBI chr 1:95,609,374...95,612,557
Ensembl chr 1:95,609,370...95,620,463

G

ribosomal protein L14

decreases expression

fipronil results in decreased expression of RPL14 mRNA

NCBI chr 8:120,286,035...120,289,160
Ensembl chr 8:120,284,645...120,289,064

G

ribosomal protein L15 like 1

decreases expression

fipronil results in decreased expression of RPL15L1 mRNA

NCBI chr12:10,227,181...10,227,989
Ensembl chr12:10,227,171...10,228,000

G

ribosomal protein L18A

increases expression

fipronil results in increased expression of RPL18A mRNA

NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546

G

ribosomal protein L32

decreases expression

fipronil results in decreased expression of RPL32 mRNA

NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612

G

ribosomal protein L36A like 1

decreases expression

fipronil results in decreased expression of RPL36AL mRNA

NCBI chr 6:87,654,808...87,656,202
Ensembl chr X:97,766,179...97,768,892
Ensembl chr10:97,766,179...97,768,892

G

ribosomal protein L7

increases expression

fipronil results in increased expression of RPL7 mRNA

NCBI chr 5:3,217,184...3,220,192

G

ribosomal protein L7A

decreases expression

fipronil results in decreased expression of RPL7A mRNA

NCBI chr 3:10,239,026...10,241,703
Ensembl chr 3:10,239,001...10,241,716

G

ribosomal protein L9

decreases expression

fipronil results in decreased expression of RPL9 mRNA

NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136
Ensembl chr 3:42,893,942...42,897,136

G

ribonuclease P/MRP subunit p38

decreases expression

fipronil results in decreased expression of RPP38 mRNA

NCBI chr17:74,914,066...74,917,742
Ensembl chr17:74,908,932...74,927,431

G

reprimo-like

decreases expression

fipronil results in decreased expression of RPRML mRNA

NCBI chr10:88,560,248...88,561,252
Ensembl chr10:88,560,248...88,561,252

G

ribosomal protein S20 like 2

increases expression

fipronil results in increased expression of RPS20L2 mRNA

NCBI chr 7:17,946,546...17,947,198
Ensembl chr 7:17,946,575...17,946,946

G

ribosomal protein s25

decreases expression

fipronil results in decreased expression of RPS25 mRNA

NCBI chr 8:44,733,623...44,735,999
Ensembl chr 8:44,733,029...44,737,271

G

ribosomal protein S27a

decreases expression

fipronil results in decreased expression of RPS27A mRNA

NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011

G

ribosomal protein S27-like

decreases expression

fipronil results in decreased expression of RPS27L mRNA

NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418

G

ribosomal protein SA

decreases expression

fipronil results in decreased expression of RPSA mRNA

NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247

G

Ras-related GTP binding C

increases expression

fipronil results in increased expression of RRAGC mRNA

NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767

G

ribonucleotide reductase regulatory subunit M2

decreases expression

fipronil results in decreased expression of RRM2 mRNA

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

RRN3 homolog, RNA polymerase I transcription factor

decreases expression

fipronil results in decreased expression of RRN3 mRNA

NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663

G

ribosomal L24 domain containing 1

decreases expression

fipronil results in decreased expression of RSL24D1 mRNA

NCBI chr 8:73,852,991...73,861,996
Ensembl chr 8:73,852,996...73,862,001

G

rubicon autophagy regulator

decreases expression
multiple interactions

fipronil results in decreased expression of RUBCN mRNA
[fipronil co-treated with DEET] results in decreased expression of RUBCN mRNA

NCBI chr11:67,907,534...67,964,347
Ensembl chr11:67,907,516...67,964,314

G

RUN and SH3 domain containing 2

increases expression

fipronil results in increased expression of RUSC2 mRNA

NCBI chr 5:57,628,397...57,675,524
Ensembl chr 5:57,629,904...57,675,524

G

retinoid X receptor alpha

decreases expression

fipronil results in decreased expression of RXRA mRNA

NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712

G

sterile alpha motif domain containing 11

decreases expression

fipronil results in decreased expression of SAMD11 mRNA

NCBI chr 5:166,831,681...166,859,805
Ensembl chr 5:166,831,663...166,850,009

G

SAP30 binding protein

decreases expression

fipronil results in decreased expression of SAP30BP mRNA

NCBI chr10:101,165,777...101,198,503
Ensembl chr10:101,165,856...101,198,502

G

sarcosine dehydrogenase

increases expression

fipronil results in increased expression of SARDH mRNA

NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874

G

SH3 domain binding kinase 1

increases expression

fipronil results in increased expression of SBK1 mRNA

NCBI chr 1:180,807,092...180,851,910
Ensembl chr 1:180,807,099...180,851,885

G

somatomedin B and thrombospondin, type 1 domain containing

increases expression

fipronil results in increased expression of SBSPON mRNA

NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420

G

sterol-C5-desaturase

increases expression

fipronil results in increased expression of SC5D mRNA

NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273

G

scavenger receptor class A, member 3

increases expression

fipronil results in increased expression of SCARA3 mRNA

NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894

G

small Cajal body-specific RNA 17

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of SCARNA17 mRNA
fipronil results in decreased expression of SCARNA17 mRNA

NCBI chr18:68,344,475...68,344,553
Ensembl chr18:68,344,475...68,344,553

G

scavenger receptor family member expressed on T-cells 1

decreases expression
multiple interactions

fipronil results in decreased expression of SCART1 mRNA
[fipronil co-treated with DEET] results in decreased expression of SCART1 mRNA

NCBI chr 1:195,020,750...195,031,807
Ensembl chr 1:195,020,750...195,031,807

G

stearoyl-CoA desaturase

increases expression

fipronil results in increased expression of SCD mRNA

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

secretoglobin family 1A member 1

decreases expression

fipronil results in decreased expression of SCGB1A1 mRNA

NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610

G

sodium voltage-gated channel beta subunit 2

decreases expression

fipronil results in decreased expression of SCN2B mRNA

NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765

G

synthesis of cytochrome C oxidase 1

decreases expression

fipronil results in decreased expression of SCO1 mRNA

NCBI chr10:51,744,656...51,757,246
Ensembl chr10:51,744,656...51,757,237

G

secernin 3

increases expression

fipronil results in increased expression of SCRN3 mRNA

NCBI chr 3:58,188,820...58,213,623
Ensembl chr 3:58,188,889...58,213,623

G

succinate dehydrogenase complex assembly factor 1

decreases expression

fipronil results in decreased expression of SDHAF1 mRNA

NCBI chr 1:85,576,207...85,577,156
Ensembl chr 1:85,576,041...85,577,366
Ensembl chr 1:85,576,041...85,577,366

G

SEC61 translocon subunit alpha 1

decreases expression

fipronil results in decreased expression of SEC61A1 mRNA

NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925

G

SEC61 translocon subunit alpha 2

increases expression

fipronil results in increased expression of SEC61A2 mRNA

NCBI chr17:72,407,574...72,445,630
Ensembl chr17:72,407,671...72,434,494

G

SECIS binding protein 2

decreases expression

fipronil results in decreased expression of SECISBP2 mRNA

NCBI chr17:13,538,513...13,569,573
Ensembl chr17:13,538,513...13,569,523

G

SEL1L family member 3

decreases expression

fipronil results in decreased expression of SEL1L3 mRNA

NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644

G

selenoprotein H

increases expression

fipronil results in increased expression of SELENOH mRNA

NCBI chr 3:69,751,850...69,753,417
Ensembl chr 3:69,752,757...69,753,417

G

selenoprotein T

increases expression

fipronil results in increased expression of SELENOT mRNA

NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427

G

stress-associated endoplasmic reticulum protein 1

decreases expression

fipronil results in decreased expression of SERP1 mRNA

NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116

G

serpin family A member 10

increases expression

fipronil results in increased expression of SERPINA10 mRNA

NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544

G

serpin family B member 6A

increases expression

fipronil results in increased expression of SERPINB6A mRNA

NCBI chr17:30,871,468...30,989,703
Ensembl chr17:30,871,468...31,014,427

G

serpin family B member 9

increases expression

fipronil results in increased expression of SERPINB9 mRNA

NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230

G

serpin family E member 1

increases expression

fipronil results in increased expression of SERPINE1 mRNA

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

SERTA domain containing 1

decreases expression

fipronil results in decreased expression of SERTAD1 mRNA

NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091

G

SEC14 and spectrin domain containing 1

decreases expression

fipronil results in decreased expression of SESTD1 mRNA

NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546

G

SET domain containing 4

increases expression

fipronil results in increased expression of SETD4 mRNA

NCBI chr11:32,829,509...32,859,162
Ensembl chr11:32,838,063...32,858,243

G

SET domain containing 5

decreases expression

fipronil results in decreased expression of SETD5 mRNA

NCBI chr 4:146,217,172...146,294,896
Ensembl chr 4:146,217,180...146,294,894

G

seizure related 6 homolog like

decreases expression

fipronil results in decreased expression of SEZ6L mRNA

NCBI chr12:44,064,901...44,221,814
Ensembl chr12:44,064,935...44,219,663

G

sideroflexin 3

increases expression

fipronil results in increased expression of SFXN3 mRNA

NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073

G

sphingosine-1-phosphate lyase 1

increases expression

fipronil results in increased expression of SGPL1 mRNA

NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084

G

SH3-domain binding protein 5

increases expression

fipronil results in increased expression of SH3BP5 mRNA

NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975

G

SH3 and multiple ankyrin repeat domains 2

increases expression

fipronil results in increased expression of SHANK2 mRNA

NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394

G

Sh3kbp1 binding protein 1

increases expression

fipronil results in increased expression of SHKBP1 mRNA

NCBI chr 1:82,636,797...82,650,330
Ensembl chr 1:82,636,797...82,650,375

G

signal-regulatory protein alpha

increases expression

fipronil results in increased expression of SIRPA mRNA

NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098

G

SIVA1, apoptosis-inducing factor

decreases expression

fipronil results in decreased expression of SIVA1 mRNA

NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690

G

S-phase kinase-associated protein 1

increases expression

fipronil results in increased expression of SKP1 mRNA

NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388

G

solute carrier family 10 member 1

increases expression

fipronil results in increased expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 12 member 5

increases expression

fipronil results in increased expression of SLC12A5 mRNA

NCBI chr 3:153,696,517...153,735,801
Ensembl chr 3:153,696,517...153,735,765

G

solute carrier family 12 member 7

increases expression

fipronil results in increased expression of SLC12A7 mRNA

NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302

G

solute carrier family 15 member 4

decreases expression

fipronil results in decreased expression of SLC15A4 mRNA

NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480

G

solute carrier family 16, member 11

decreases expression

fipronil results in decreased expression of SLC16A11 mRNA

NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915

G

solute carrier family 16, member 13

decreases expression

fipronil results in decreased expression of SLC16A13 mRNA

NCBI chr10:54,925,973...54,937,860
Ensembl chr10:54,926,760...54,937,788

G

solute carrier family 16 member 2

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of SLC16A2 mRNA
fipronil results in decreased expression of SLC16A2 mRNA

NCBI chr X:68,725,365...68,848,572
Ensembl chr X:68,723,261...68,848,771

G

solute carrier family 19 member 1

decreases expression

fipronil results in decreased expression of SLC19A1 mRNA

NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972

G

solute carrier family 20 member 2

increases expression

fipronil results in increased expression of SLC20A2 mRNA

NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711

G

solute carrier family 22, member 23

decreases expression

fipronil results in decreased expression of SLC22A23 mRNA

NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790

G

solute carrier family 25 member 32

decreases expression

fipronil results in decreased expression of SLC25A32 mRNA

NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:70,142,964...70,160,770

G

solute carrier family 25, member 51

increases expression

fipronil results in increased expression of SLC25A51 mRNA

NCBI chr 5:59,649,980...59,663,454
Ensembl chr 5:59,649,744...59,663,581

G

solute carrier family 29 member 3

decreases expression

fipronil results in decreased expression of SLC29A3 mRNA

NCBI chr20:28,645,265...28,685,388
Ensembl chr20:28,647,391...28,685,388

G

solute carrier family 2 member 4

increases expression

fipronil results in increased expression of SLC2A4 mRNA

NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565

G

solute carrier family 35 member B3

increases expression

fipronil results in increased expression of SLC35B3 mRNA

NCBI chr17:25,846,590...25,873,115
Ensembl chr17:25,846,748...25,872,557

G

solute carrier family 35 member B4

decreases expression

fipronil results in decreased expression of SLC35B4 mRNA

NCBI chr 4:62,776,993...62,799,013
Ensembl chr 4:62,776,993...62,799,003

G

solute carrier family 35, member F6

decreases expression

fipronil results in decreased expression of SLC35F6 mRNA

NCBI chr 6:25,725,822...25,737,720
Ensembl chr 6:25,725,819...25,737,730

G

solute carrier family 38, member 2

decreases expression

fipronil results in decreased expression of SLC38A2 mRNA

NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436

G

solute carrier family 3 member 2

increases expression

fipronil results in increased expression of SLC3A2 mRNA

NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 51 member A

increases expression

fipronil results in increased expression of SLC51A mRNA

NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485

G

SLC51 subunit beta

increases expression
multiple interactions

fipronil results in increased expression of SLC51B mRNA
[fipronil co-treated with DEET] results in increased expression of SLC51B mRNA

NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145

G

solute carrier family 5 member 5

decreases expression
increases expression

fipronil results in decreased expression of SLC5A5 mRNA
fipronil results in increased expression of SLC5A5 mRNA

PMID:23962444 PMID:31881178

NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697

G

solute carrier family 6 member 9

decreases expression

fipronil results in decreased expression of SLC6A9 mRNA

NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728

G

solute carrier family 8 member B1

increases expression

fipronil results in increased expression of SLC8B1 mRNA

NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031

G

solute carrier organic anion transporter family, member 1a4

multiple interactions
increases expression

NR1I2 gene mutant form inhibits the reaction [fipronil results in increased expression of SLCO1A4 mRNA]

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

solute carrier organic anion transporter family, member 1A5

increases expression

fipronil results in increased expression of SLCO1A5 mRNA

NCBI chr 4:175,172,390...175,254,598
Ensembl chr 4:174,710,004...175,254,573

G

SRA stem-loop interacting RNA binding protein

decreases expression

fipronil results in decreased expression of SLIRP mRNA

NCBI chr 6:107,088,760...107,097,791
Ensembl chr 6:107,088,403...107,097,791

G

SMAD family member 3

decreases expression

fipronil results in decreased expression of SMAD3 mRNA

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

SWI/SNF related BAF chromatin remodeling complex subunit E1

decreases expression

fipronil results in decreased expression of SMARCE1 mRNA

NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989

G

SMG7 nonsense mediated mRNA decay factor

decreases expression

fipronil results in decreased expression of SMG7 mRNA

NCBI chr13:64,986,145...65,050,698
Ensembl chr13:64,987,434...65,050,582

G

small integral membrane protein 30

multiple interactions

[fipronil co-treated with DEET] results in increased expression of SMIM30 mRNA

NCBI chr X:34,443,180...34,443,365

G

sphingomyelin phosphodiesterase 3

increases expression

fipronil results in increased expression of SMPD3 mRNA

NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749

G

small nuclear RNA activating complex, polypeptide 3

decreases expression

fipronil results in decreased expression of SNAPC3 mRNA

NCBI chr 5:97,817,827...97,868,494
Ensembl chr 5:97,817,947...97,844,650

G

small nuclear ribonucleoprotein polypeptide A

decreases expression

fipronil results in decreased expression of SNRPA mRNA

NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538

G

small nuclear ribonucleoprotein polypeptides B and B1

decreases expression

fipronil results in decreased expression of SNRPB mRNA

NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339

G

small nuclear ribonucleoprotein polypeptide C

decreases expression

fipronil results in decreased expression of SNRPC mRNA

NCBI chr20:5,888,453...5,906,638
Ensembl chr20:5,888,453...5,906,638

G

small nuclear ribonucleoprotein polypeptide G

decreases expression

fipronil results in decreased expression of SNRPG mRNA

NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826

G

sorting nexin 10

increases expression

fipronil results in increased expression of SNX10 mRNA

NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996

G

sorting nexin 14

increases expression

fipronil results in increased expression of SNX14 mRNA

NCBI chr 8:89,283,673...89,390,597
Ensembl chr 8:89,298,114...89,390,580

G

sorting nexin 15

decreases expression

fipronil results in decreased expression of SNX15 mRNA

NCBI chr 1:203,417,029...203,426,173
Ensembl chr 1:203,417,029...203,426,247

G

sorting nexin family member 21

increases expression

fipronil results in increased expression of SNX21 mRNA

NCBI chr 3:153,522,474...153,532,235
Ensembl chr 3:153,522,486...153,532,221

G

sorting nexin 8

increases expression

fipronil results in increased expression of SNX8 mRNA

PMID:23962444 PMID:34044035

NCBI chr12:14,251,829...14,300,435
Ensembl chr12:14,251,859...14,300,432

G

sterol O-acyltransferase 2

decreases expression

fipronil results in decreased expression of SOAT2 mRNA

NCBI chr 7:133,281,818...133,294,915
Ensembl chr 7:133,281,818...133,294,915

G

suppressor of cytokine signaling 3

increases expression

fipronil results in increased expression of SOCS3 mRNA

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

superoxide dismutase 1

decreases expression

fipronil results in decreased expression of SOD1 mRNA
fipronil results in decreased expression of SOD1 protein

PMID:25721553 PMID:36113622

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

sortilin related receptor 1

increases expression

fipronil results in increased expression of SORL1 mRNA

NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513

G

SRY-box transcription factor 13

increases expression

fipronil results in increased expression of SOX13 mRNA

NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762

G

secreted protein acidic and cysteine rich

increases expression

fipronil results in increased expression of SPARC mRNA

NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396

G

SPATA31 subfamily D member 1

increases expression

fipronil results in increased expression of SPATA31D1 mRNA

NCBI chr17:4,942,754...4,948,640
Ensembl chr17:4,942,754...4,948,640

G

SPC25 component of NDC80 kinetochore complex

increases expression

fipronil results in increased expression of SPC25 mRNA

NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959

G

signal peptidase complex subunit 2

decreases expression

fipronil results in decreased expression of SPCS2 mRNA

NCBI chr 1:154,163,724...154,183,152
Ensembl chr 1:154,163,724...154,183,186

G

serine peptidase inhibitor, Kazal type 1

increases expression

fipronil results in increased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

SPNS lysolipid transporter 2, sphingosine-1-phosphate

decreases expression

fipronil results in decreased expression of SPNS2 mRNA

NCBI chr10:57,067,348...57,105,969
Ensembl chr10:57,066,897...57,105,957

G

sprouty RTK signaling antagonist 1

decreases expression

fipronil results in decreased expression of SPRY1 mRNA

NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189

G

SPRY domain containing 7

increases expression

fipronil results in increased expression of SPRYD7 mRNA

NCBI chr15:35,707,185...35,727,704
Ensembl chr15:35,707,060...35,727,509

G

sequestosome 1

increases expression

fipronil results in increased expression of SQSTM1 protein

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

steroid 5 alpha-reductase 3

decreases expression

fipronil results in decreased expression of SRD5A3 mRNA

NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747

G

SLIT-ROBO Rho GTPase activating protein 2

increases expression

fipronil results in increased expression of SRGAP2 mRNA

NCBI chr13:42,745,956...42,967,091
Ensembl chr13:42,745,947...42,967,058

G

signal recognition particle 14

decreases expression

fipronil results in decreased expression of SRP14 mRNA

NCBI chr 3:105,442,184...105,445,875
Ensembl chr 3:105,442,198...105,445,859

G

signal recognition particle 68

increases expression

fipronil results in increased expression of SRP68 mRNA

NCBI chr10:101,481,213...101,508,035
Ensembl chr10:101,481,212...101,508,035

G

SRSF protein kinase 3

increases expression

fipronil results in increased expression of SRPK3 mRNA

NCBI chr X:151,510,452...151,515,208
Ensembl chr X:151,510,539...151,515,198

G

serine and arginine rich splicing factor 5

increases expression

fipronil results in increased expression of SRSF5 mRNA

NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177

G

single-stranded DNA binding protein 2

decreases expression

fipronil results in decreased expression of SSBP2 mRNA

NCBI chr 2:22,650,488...22,938,669
Ensembl chr 2:22,651,258...22,933,696

G

signal sequence receptor subunit 2

decreases expression

fipronil results in decreased expression of SSR2 mRNA

NCBI chr 2:174,048,291...174,057,043
Ensembl chr 2:174,048,460...174,057,042

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 4

increases expression

fipronil results in increased expression of ST3GAL4 mRNA

NCBI chr 8:33,415,666...33,465,319
Ensembl chr 8:33,415,671...33,524,389

G

SH3 and cysteine rich domain 3

decreases expression

fipronil results in decreased expression of STAC3 mRNA

NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589

G

STAG3 cohesin complex component

increases expression

fipronil results in increased expression of STAG3 mRNA

NCBI chr12:17,284,677...17,314,936
Ensembl chr12:17,284,794...17,314,935

G

stanniocalcin 1

increases expression

fipronil results in increased expression of STC1 mRNA

NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264

G

serine/threonine kinase 24

decreases expression

fipronil results in decreased expression of STK24 mRNA

NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553

G

stathmin 1

increases expression

fipronil results in increased expression of STMN1 mRNA

NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154

G

stathmin 3

decreases expression

fipronil results in decreased expression of STMN3 mRNA

NCBI chr 3:168,416,810...168,424,946
Ensembl chr 3:168,416,810...168,425,056

G

spermatid perinuclear RNA binding protein

increases expression

fipronil results in increased expression of STRBP mRNA

NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949

G

syntaxin 18

increases expression

fipronil results in increased expression of STX18 mRNA

NCBI chr14:72,670,683...72,761,423
Ensembl chr14:72,670,411...72,761,464

G

syntaxin 2

increases expression

fipronil results in increased expression of STX2 mRNA

NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751

G

SUB1 regulator of transcription

decreases expression

fipronil results in decreased expression of SUB1 mRNA

NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436

G

sulfotransferase family 1A member 1

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in increased expression of SULT1A1 mRNA
fipronil results in decreased expression of SULT1A1 mRNA

PMID:27091632 PMID:31881178

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

sulfotransferase family 1B member 1

increases expression
decreases expression
multiple interactions

fipronil results in increased expression of SULT1B1 mRNA
fipronil results in decreased expression of SULT1B1 mRNA
[fipronil co-treated with DEET] results in decreased expression of SULT1B1 mRNA

PMID:22447239 PMID:23962444 PMID:27091632

NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483

G

sulfotransferase family 1C member 2A

increases expression
multiple interactions

fipronil results in increased expression of SULT1C2 mRNA
[fipronil co-treated with DEET] results in increased expression of SULT1C2 mRNA

PMID:23962444 PMID:27091632

NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734

G

sulfotransferase family 1E member 1

decreases expression
multiple interactions

fipronil results in decreased expression of SULT1E1 mRNA
[fipronil co-treated with DEET] results in decreased expression of SULT1E1 mRNA

NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275

G

sulfotransferase family 2A member 1

multiple interactions

[fipronil co-treated with DEET] results in increased expression of SULT2A1 mRNA

NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134

G

sulfotransferase family 4A, member 1

decreases expression

fipronil results in decreased expression of SULT4A1 mRNA

NCBI chr 7:115,216,066...115,240,156
Ensembl chr 7:115,216,066...115,240,085

G

sulfite oxidase

decreases expression

fipronil results in decreased expression of SUOX mRNA

NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038

G

supervillin

increases expression

fipronil results in increased expression of SVIL mRNA

NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404

G

spectrin repeat containing, nuclear envelope family member 3

multiple interactions

[fipronil co-treated with DEET] results in decreased expression of SYNE3 mRNA

NCBI chr 6:123,872,895...123,964,773
Ensembl chr 6:123,873,174...123,953,409

G

transcriptional adaptor 1

decreases expression

fipronil results in decreased expression of TADA1 mRNA

NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504

G

transgelin

increases expression

fipronil results in increased expression of TAGLN mRNA

NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668

G

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

increases expression

fipronil results in increased expression of TANC1 mRNA

NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627

G

TBC1 domain family, member 16

decreases expression

fipronil results in decreased expression of TBC1D16 mRNA

NCBI chr10:104,400,963...104,486,698
Ensembl chr10:104,402,398...104,486,670

G

TATA box binding protein

decreases expression

fipronil results in decreased expression of TBP mRNA

NCBI chr 1:56,463,330...56,480,430
Ensembl chr 1:56,463,618...56,510,016

G

transforming growth factor beta regulator 4

decreases expression

fipronil results in decreased expression of TBRG4 mRNA

NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756

G

T cell activation inhibitor, mitochondrial

increases expression

fipronil results in increased expression of TCAIM mRNA

NCBI chr 8:122,414,827...122,446,105
Ensembl chr 8:122,414,818...122,446,092

G

tectonin beta-propeller repeat containing 1

increases expression

fipronil results in increased expression of TECPR1 mRNA

NCBI chr12:10,391,587...10,420,462
Ensembl chr12:10,391,696...10,419,611

G

TEF transcription factor, PAR bZIP family member

increases expression

fipronil results in increased expression of TEF mRNA

NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783

G

teneurin transmembrane protein 4

increases expression

fipronil results in increased expression of TENM4 mRNA

NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144

G

terminal nucleotidyltransferase 4A

increases expression

fipronil results in increased expression of TENT4A mRNA

NCBI chr 1:33,765,949...33,799,405
Ensembl chr 1:33,765,672...33,799,433

G

terminal nucleotidyltransferase 5A

decreases expression
increases expression

fipronil results in decreased expression of TENT5A mRNA
fipronil results in increased expression of TENT5A mRNA

PMID:23962444 PMID:31881178

NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045

G

testis expressed 2

increases expression

fipronil results in increased expression of TEX2 mRNA

NCBI chr10:91,436,629...91,546,240
Ensembl chr10:91,436,694...91,546,270

G

transcription factor AP-2 epsilon

increases expression

fipronil results in increased expression of TFAP2E mRNA

NCBI chr 5:139,009,447...139,030,695
Ensembl chr 5:139,009,453...139,031,108

G

tissue factor pathway inhibitor

decreases expression

fipronil results in decreased expression of TFPI mRNA

NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880

G

transferrin receptor

increases expression

fipronil results in increased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

thyroglobulin

increases expression

fipronil results in increased expression of TG mRNA

NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210

G

tyrosine hydroxylase

decreases expression

fipronil results in decreased expression of TH protein

NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767

G

thyroid hormone receptor alpha

increases expression

fipronil results in increased expression of THRA mRNA

NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936

G

thyroid hormone responsive

increases expression
multiple interactions

fipronil results in increased expression of THRSP mRNA
[fipronil co-treated with DEET] results in increased expression of THRSP mRNA

NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075

G

THUMPD3 antisense RNA 1

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of THUMPD3-AS1 mRNA
fipronil results in decreased expression of THUMPD3-AS1 mRNA

NCBI chr 4:146,210,520...146,217,026

G

TRAF-interacting protein with forkhead-associated domain

decreases expression

fipronil results in decreased expression of TIFA mRNA

NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841

G

tigger transposable element derived 2

increases expression

fipronil results in increased expression of TIGD2 mRNA

NCBI chr 4:88,414,366...88,417,458
Ensembl chr 4:88,414,518...88,417,785

G

translocase of inner mitochondrial membrane 23

decreases expression

fipronil results in decreased expression of TIMM23 mRNA

NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379

G

tubulointerstitial nephritis antigen-like 1

increases expression

fipronil results in increased expression of TINAGL1 mRNA

NCBI chr 5:142,513,710...142,523,730
Ensembl chr 5:142,513,714...142,523,720

G

TERF1 interacting nuclear factor 2

increases expression

fipronil results in increased expression of TINF2 mRNA

NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984

G

toll-like receptor 2

decreases expression

fipronil results in decreased expression of TLR2 mRNA

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

T-cell leukemia, homeobox 3

decreases expression

fipronil results in decreased expression of TLX3 mRNA

NCBI chr10:17,789,706...17,792,207
Ensembl chr10:17,790,053...17,792,207

G

transmembrane and coiled-coil domains 1

decreases expression

fipronil results in decreased expression of TMCO1 mRNA

NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555

G

transmembrane protein 104

decreases expression

fipronil results in decreased expression of TMEM104 mRNA

NCBI chr10:100,427,244...100,485,890
Ensembl chr10:100,427,307...100,483,354

G

transmembrane protein 106B

decreases expression

fipronil results in decreased expression of TMEM106B mRNA

NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619

G

transmembrane protein 115

decreases expression

fipronil results in decreased expression of TMEM115 mRNA

NCBI chr 8:108,207,463...108,212,327
Ensembl chr 8:108,207,654...108,212,298

G

transmembrane protein 129, E3 ubiquitin ligase

decreases expression

fipronil results in decreased expression of TMEM129 mRNA

NCBI chr14:77,065,391...77,070,871
Ensembl chr14:77,065,841...77,070,865

G

transmembrane protein 150A

increases expression

fipronil results in increased expression of TMEM150A mRNA

NCBI chr 4:104,410,271...104,414,630
Ensembl chr 4:104,410,516...104,429,349

G

transmembrane protein 184C

decreases expression

fipronil results in decreased expression of TMEM184C mRNA

NCBI chr19:30,345,183...30,361,275
Ensembl chr19:30,345,290...30,361,269

G

transmembrane protein 204

increases expression

fipronil results in increased expression of TMEM204 mRNA

NCBI chr10:14,076,518...14,104,849
Ensembl chr10:14,076,519...14,101,920

G

transmembrane protein 212

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of TMEM212 mRNA
fipronil results in decreased expression of TMEM212 mRNA

NCBI chr 2:110,775,950...110,813,313
Ensembl chr 2:110,775,953...110,813,273

G

transmembrane protein 222

decreases expression

fipronil results in decreased expression of TMEM222 mRNA

NCBI chr 5:145,465,847...145,477,932
Ensembl chr 5:145,465,847...145,484,491

G

transmembrane protein 240

decreases expression

fipronil results in decreased expression of TMEM240 mRNA

NCBI chr 5:166,344,000...166,350,210
Ensembl chr 5:166,344,386...166,350,636

G

transmembrane protein 62

increases expression

fipronil results in increased expression of TMEM62 mRNA

NCBI chr 3:107,921,940...107,961,830
Ensembl chr 3:107,927,307...107,961,795

G

TMEM9 domain family, member B

increases expression

fipronil results in increased expression of TMEM9B mRNA

NCBI chr 1:163,755,307...163,783,880
Ensembl chr 1:163,764,433...163,783,278

G

transmembrane serine protease 4

increases expression

fipronil results in increased expression of TMPRSS4 mRNA

NCBI chr 8:45,475,819...45,508,409
Ensembl chr 8:45,476,053...45,508,409

G

tumor necrosis factor

increases expression

fipronil results in increased expression of TNF mRNA

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 8

increases expression

fipronil results in increased expression of TNFAIP8 mRNA

NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517

G

TNF receptor superfamily member 12A

decreases expression

fipronil results in decreased expression of TNFRSF12A mRNA

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

tyrosine kinase, non-receptor, 2

increases expression

fipronil results in increased expression of TNK2 mRNA

NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009

G

tenascin N

decreases expression

fipronil results in decreased expression of TNN mRNA

NCBI chr13:72,319,160...72,386,362
Ensembl chr13:72,319,155...72,408,156

G

target of myb1 like 2 membrane trafficking protein

increases expression

fipronil results in increased expression of TOM1L2 mRNA

NCBI chr10:45,036,034...45,158,168
Ensembl chr10:45,036,035...45,158,032

G

translocase of outer mitochondrial membrane 40 like

increases expression

fipronil results in increased expression of TOMM40L mRNA

NCBI chr13:83,636,692...83,641,654
Ensembl chr13:83,638,195...83,641,654

G

tumor protein p53

affects localization

fipronil affects the localization of TP53 protein

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tumor protein p53 inducible protein 3

increases expression

fipronil results in increased expression of TP53I3 mRNA

NCBI chr 6:27,818,327...27,825,753

G

TPD52 like 2

decreases expression

fipronil results in decreased expression of TPD52L2 mRNA

NCBI chr 3:168,598,449...168,618,201
Ensembl chr 3:168,594,609...168,619,762

G

tripeptidyl peptidase 1

increases expression

fipronil results in increased expression of TPP1 mRNA

NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129

G

tubulin polymerization-promoting protein family member 3

decreases expression

fipronil results in decreased expression of TPPP3 mRNA

NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577

G

tripartite motif-containing 21

decreases expression

fipronil results in decreased expression of TRIM21 mRNA

NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440

G

tripartite motif-containing 25

increases expression

fipronil results in increased expression of TRIM25 mRNA

NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257

G

tripartite motif-containing 32

increases expression

fipronil results in increased expression of TRIM32 mRNA

NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018

G

tripartite motif-containing 37

increases expression

fipronil results in increased expression of TRIM37 mRNA

NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558

G

thyroid hormone receptor interactor 10

increases expression

fipronil results in increased expression of TRIP10 mRNA

NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799

G

telomerase RNA component interacting RNase

decreases expression

fipronil results in decreased expression of TRIR mRNA

NCBI chr19:23,125,083...23,128,502
Ensembl chr19:23,125,083...23,128,510

G

tRNA methyltransferase 10A

increases expression

fipronil results in increased expression of TRMT10A mRNA

NCBI chr 2:226,669,445...226,684,166
Ensembl chr 2:226,669,832...226,684,151

G

tRNA methyltransferase 12

decreases expression

fipronil results in decreased expression of TRMT12 mRNA

NCBI chr 7:90,417,846...90,419,472
Ensembl chr 7:90,417,862...90,419,867

G

trophinin associated protein

increases expression

fipronil results in increased expression of TROAP mRNA

NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365

G

transient receptor potential cation channel, subfamily V, member 4

decreases expression

fipronil results in decreased expression of TRPV4 mRNA

NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517

G

TruB pseudouridine synthase family member 2

increases expression

fipronil results in increased expression of TRUB2 mRNA

NCBI chr 3:13,049,220...13,059,836
Ensembl chr 3:13,033,745...13,059,930

G

TSC22 domain family, member 1

decreases expression

fipronil results in decreased expression of TSC22D1 mRNA

NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958

G

TSC22 domain family, member 4

increases expression

fipronil results in increased expression of TSC22D4 mRNA

NCBI chr12:18,939,150...18,952,008
Ensembl chr12:18,914,398...18,952,008

G

tRNA splicing endonuclease subunit 54

decreases expression

fipronil results in decreased expression of TSEN54 mRNA

NCBI chr10:101,041,607...101,050,088
Ensembl chr10:101,042,503...101,050,087

G

tetraspanin 18

increases expression

fipronil results in increased expression of TSPAN18 mRNA

NCBI chr 3:79,160,060...79,299,907
Ensembl chr 3:79,161,662...79,299,852

G

tetraspanin 4

decreases expression

fipronil results in decreased expression of TSPAN4 mRNA

NCBI chr 1:196,571,307...196,593,842
Ensembl chr 1:196,572,228...196,617,448

G

TSR2, ribosome maturation factor

decreases expression

fipronil results in decreased expression of TSR2 mRNA

NCBI chr X:20,064,102...20,072,673
Ensembl chr X:20,064,103...20,072,620

G

tumor suppressing subtransferable candidate 4

decreases expression

fipronil results in decreased expression of TSSC4 mRNA

NCBI chr 1:198,251,986...198,254,810
Ensembl chr 1:198,235,487...198,254,980

G

tetratricopeptide repeat domain 13

increases expression

fipronil results in increased expression of TTC13 mRNA

NCBI chr19:52,637,599...52,692,196
Ensembl chr19:52,637,431...52,692,198

G

tetratricopeptide repeat domain 38

increases expression

fipronil results in increased expression of TTC38 mRNA

NCBI chr 7:116,925,273...116,948,616
Ensembl chr 7:116,925,257...116,948,611

G

tetratricopeptide repeat domain 7A

increases expression

fipronil results in increased expression of TTC7A mRNA

NCBI chr 6:7,159,285...7,261,826
Ensembl chr 6:7,159,061...7,261,892

G

tubulin tyrosine ligase like 9

increases expression

fipronil results in increased expression of TTLL9 mRNA

NCBI chr 3:141,429,351...141,475,965
Ensembl chr 3:141,429,444...141,475,865

G

tweety family member 1

decreases expression

fipronil results in decreased expression of TTYH1 mRNA

NCBI chr 1:70,053,312...70,071,872
Ensembl chr 1:70,053,324...70,071,845

G

tubulin, beta 6 class V

increases expression

fipronil results in increased expression of TUBB6 mRNA

NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418

G

tumor suppressor candidate 3

increases expression

fipronil results in increased expression of TUSC3 mRNA

NCBI chr16:53,196,195...53,345,241
Ensembl chr16:53,196,195...53,344,781

G

thioredoxin 1

increases expression
decreases expression

fipronil results in increased expression of TXN1 mRNA
fipronil results in decreased expression of TXN1 mRNA

PMID:31881178 PMID:34044035

NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629

G

thioredoxin interacting protein

decreases expression

fipronil results in decreased expression of TXNIP mRNA

NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886

G

thymidine phosphorylase

decreases expression

fipronil results in decreased expression of TYMP mRNA

NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874

G

thymidylate synthetase

increases expression

fipronil results in increased expression of TYMS mRNA

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

TYRO3 protein tyrosine kinase

increases expression

fipronil results in increased expression of TYRO3 mRNA

NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142

G

ubiquitin-like modifier activating enzyme 2

decreases expression

fipronil results in decreased expression of UBA2 mRNA

NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682

G

ubiquitin associated protein 2-like

increases expression

fipronil results in increased expression of UBAP2L mRNA

NCBI chr 2:175,438,703...175,494,085
Ensembl chr 2:175,438,703...175,493,998

G

ubiquitin B

decreases expression

fipronil results in decreased expression of UBB mRNA

NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333

G

ubiquitin-conjugating enzyme E2E 2

decreases expression

fipronil results in decreased expression of UBE2E2 mRNA

NCBI chr15:6,980,241...7,257,912
Ensembl chr15:6,980,474...7,257,532

G

ubiquitin-conjugating enzyme E2I

decreases expression

fipronil results in decreased expression of UBE2I mRNA

NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443

G

ubiquitin-conjugating enzyme E2, J2

decreases expression

fipronil results in decreased expression of UBE2J2 mRNA

NCBI chr 5:166,533,374...166,547,811
Ensembl chr 5:166,533,418...166,547,804

G

ubiquitin-conjugating enzyme E2Z

decreases expression

fipronil results in decreased expression of UBE2Z mRNA

NCBI chr10:80,997,816...81,016,936
Ensembl chr10:80,997,817...81,016,936

G

ubiquitin protein ligase E3B

increases expression

fipronil results in increased expression of UBE3B mRNA

NCBI chr12:42,183,756...42,230,094
Ensembl chr12:42,183,760...42,230,094

G

ubiquitin protein ligase E3D

decreases expression

fipronil results in decreased expression of UBE3D mRNA

NCBI chr 8:87,245,503...87,413,104
Ensembl chr 8:87,245,589...87,413,057

G

ubiquitin protein ligase E3 component n-recognin 4

increases expression

fipronil results in increased expression of UBR4 mRNA

NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784

G

UBX domain protein 8

increases expression

fipronil results in increased expression of UBXN8 mRNA

NCBI chr16:58,536,086...58,557,684
Ensembl chr16:58,536,086...58,557,684

G

urocortin

decreases expression

fipronil results in decreased expression of UCN mRNA

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

G

ubiquitin-fold modifier 1

decreases expression

fipronil results in decreased expression of UFM1 mRNA

NCBI chr 2:137,969,476...137,977,620
Ensembl chr 2:137,966,678...137,978,089
Ensembl chr 2:137,966,678...137,978,089

G

UDP glucuronosyltransferase family 1 member A1

increases expression

fipronil results in increased expression of UGT1A1 mRNA

PMID:22447239 PMID:23962444

NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases expression

fipronil results in increased expression of UGT1A2 mRNA

NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A6

increases expression

fipronil results in increased expression of UGT1A6 mRNA

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 1 member A9

increases expression

fipronil results in increased expression of UGT1A9 mRNA

NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

UDP glucuronosyltransferase family 2 member A3

increases expression

fipronil results in increased expression of UGT2A3 mRNA

NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729

G

UDP glucuronosyltransferase 2 family, polypeptide B1

increases expression

fipronil results in increased expression of UGT2B1 mRNA

NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986

G

UDP glucuronosyltransferase family 2 member B15

increases expression

fipronil results in increased expression of UGT2B15 mRNA

NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589

G

unc-5 netrin receptor B

increases expression

fipronil results in increased expression of UNC5B mRNA

NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537

G

uroplakin 1A

decreases expression

fipronil results in decreased expression of UPK1A mRNA

NCBI chr 1:85,859,672...85,870,147
Ensembl chr 1:85,859,671...85,870,354

G

ubiquinol-cytochrome c reductase core protein 1

decreases expression

fipronil results in decreased expression of UQCRC1 mRNA

NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480

G

ubiquitin related modifier 1

decreases expression

fipronil results in decreased expression of URM1 mRNA

NCBI chr 3:13,100,340...13,117,064
Ensembl chr 3:13,092,200...13,117,642
Ensembl chr 3:13,092,200...13,117,642

G

ubiquitin specific peptidase 9, X-linked

increases expression

fipronil results in increased expression of USP9X mRNA

NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711

G

UDP-glucuronate decarboxylase 1

increases expression

fipronil results in increased expression of UXS1 mRNA

NCBI chr 9:653,740...731,121
Ensembl chr 9:653,659...756,334

G

VANGL planar cell polarity protein 1

increases expression

fipronil results in increased expression of VANGL1 mRNA

PMID:23962444 PMID:34044035

NCBI chr 2:189,586,681...189,637,609
Ensembl chr 2:189,589,229...189,637,619

G

vasodilator-stimulated phosphoprotein

increases expression

fipronil results in increased expression of VASP mRNA

NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061

G

vav guanine nucleotide exchange factor 2

decreases expression

fipronil results in decreased expression of VAV2 mRNA

NCBI chr 3:10,584,688...10,754,128
Ensembl chr 3:10,584,688...10,754,052

G

vav guanine nucleotide exchange factor 3

increases expression
decreases expression

fipronil results in increased expression of VAV3 mRNA
fipronil results in decreased expression of VAV3 mRNA

PMID:23962444 PMID:34044035

NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321

G

vascular endothelial growth factor B

increases expression

fipronil results in increased expression of VEGFB mRNA

NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944

G

vitamin K epoxide reductase complex, subunit 1

decreases expression

fipronil results in decreased expression of VKORC1 mRNA

NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008

G

vanin 1

increases expression

fipronil results in increased expression of VNN1 mRNA

NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395

G

vomeronasal 1 receptor 10

multiple interactions
decreases expression

[fipronil co-treated with DEET] results in decreased expression of VN1R2 mRNA
fipronil results in decreased expression of VN1R2 mRNA

NCBI chr 1:60,064,704...60,065,639
Ensembl chr 1:60,064,501...60,082,218

G

vomeronasal 2 receptor, 35

decreases expression

fipronil results in decreased expression of VOM2R35 mRNA

NCBI chr 1:73,210,417...73,227,703
Ensembl chr 1:73,167,047...73,293,895

G

VPS29 retromer complex component

increases expression

fipronil results in increased expression of VPS29 mRNA

NCBI chr12:34,208,911...34,217,977
Ensembl chr12:34,207,263...34,217,964

G

VPS37B subunit of ESCRT-I

increases expression

fipronil results in increased expression of VPS37B mRNA

NCBI chr12:32,560,047...32,589,015
Ensembl chr12:32,560,047...32,589,014

G

vacuolar protein sorting 72 homolog

decreases expression

fipronil results in decreased expression of VPS72 mRNA

NCBI chr 2:182,678,594...182,690,185
Ensembl chr 2:182,678,609...182,690,182

G

VRK serine/threonine kinase 1

decreases expression

fipronil results in decreased expression of VRK1 mRNA

NCBI chr 6:124,914,770...124,981,508
Ensembl chr 6:124,914,855...124,981,436

G

vexin

decreases expression

fipronil results in decreased expression of VXN mRNA

NCBI chr 5:9,659,213...9,684,684
Ensembl chr 5:9,659,213...9,684,684

G

WASP family member 1

decreases expression

fipronil results in decreased expression of WASF1 mRNA

NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996

G

WASH complex subunit 5

increases expression

fipronil results in increased expression of WASHC5 mRNA

NCBI chr 7:90,884,192...90,936,096
Ensembl chr 7:90,884,197...90,936,103

G

WD repeat and FYVE domain containing 1

increases expression

fipronil results in increased expression of WDFY1 mRNA

NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775

G

WD repeat domain 1

increases expression

fipronil results in increased expression of WDR1 mRNA

NCBI chr14:72,258,032...72,291,768
Ensembl chr14:72,257,956...72,291,766

G

WD repeat domain 43

decreases expression

fipronil results in decreased expression of WDR43 mRNA

NCBI chr 6:23,845,499...23,884,846
Ensembl chr 6:23,845,499...23,884,846

G

WD repeat domain 74

decreases expression

fipronil results in decreased expression of WDR74 mRNA

NCBI chr 1:205,631,769...205,636,558
Ensembl chr 1:205,631,824...205,636,563

G

WD and tetratricopeptide repeats 1

decreases expression

fipronil results in decreased expression of WDTC1 mRNA

NCBI chr 5:145,491,460...145,559,631
Ensembl chr 5:145,491,466...145,540,408

G

whirlin

decreases expression

fipronil results in decreased expression of WHRN mRNA

NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223

G

WD repeat domain, phosphoinositide interacting 2

decreases expression

fipronil results in decreased expression of WIPI2 mRNA

NCBI chr12:11,911,369...11,939,799
Ensembl chr12:11,911,337...11,939,794

G

Wnt family member 7B

decreases expression

fipronil results in decreased expression of WNT7B mRNA

NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581

G

xanthine dehydrogenase

increases activity
multiple interactions

fipronil results in increased activity of XDH protein
Allopurinol inhibits the reaction [fipronil results in increased activity of XDH protein]

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

X inactive specific transcript

decreases expression
multiple interactions

fipronil results in decreased expression of XIST mRNA
[fipronil co-treated with DEET] results in decreased expression of XIST mRNA

NCBI chr X:68,474,987...68,492,500

G

exportin 7

decreases expression

fipronil results in decreased expression of XPO7 mRNA

NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050

G

X-ray repair cross complementing 1

increases expression

fipronil results in increased expression of XRCC1 mRNA

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

Yes1 associated transcriptional regulator

increases expression

fipronil results in increased expression of YAP1 mRNA

NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010

G

tyrosyl-tRNA synthetase 2

increases expression

fipronil results in increased expression of YARS2 mRNA

NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125

G

yrdC N(6)-threonylcarbamoyltransferase domain containing

decreases expression

fipronil results in decreased expression of YRDC mRNA

NCBI chr 5:137,110,244...137,115,127
Ensembl chr 5:137,110,279...137,115,120

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreases expression

fipronil results in decreased expression of YWHAZ mRNA

NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668

G

zinc finger and BTB domain containing 1

decreases expression

fipronil results in decreased expression of ZBTB1 mRNA

NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996

G

zinc finger and BTB domain containing 4

increases expression

fipronil results in increased expression of ZBTB4 mRNA

NCBI chr10:54,480,698...54,501,492
Ensembl chr10:54,485,071...54,501,492

G

zinc finger and BTB domain containing 49

decreases expression

fipronil results in decreased expression of ZBTB49 mRNA

NCBI chr14:72,590,692...72,612,404
Ensembl chr14:72,590,708...72,612,404

G

zinc finger CCCH type containing 12A

decreases expression

fipronil results in decreased expression of ZC3H12A mRNA

NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351

G

zinc finger CCCH-type containing 4

decreases expression

fipronil results in decreased expression of ZC3H4 mRNA

NCBI chr 1:77,106,309...77,143,827
Ensembl chr 1:77,106,250...77,142,691

G

zinc finger CCHC-type containing 24

decreases expression

fipronil results in decreased expression of ZCCHC24 mRNA

NCBI chr16:1,274,544...1,326,664
Ensembl chr16:1,274,548...1,326,696

G

zinc finger DHHC-type palmitoyltransferase 2

increases expression

fipronil results in increased expression of ZDHHC2 mRNA

NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060

G

zinc finger protein 217

increases expression

fipronil results in increased expression of ZFP217 mRNA

NCBI chr 3:158,890,464...158,931,148
Ensembl chr 3:158,892,265...158,913,040

G

zinc finger protein 251

increases expression

fipronil results in increased expression of ZFP251 mRNA

NCBI chr 7:108,568,564...108,598,593
Ensembl chr 7:108,568,597...108,598,623

G

zinc finger protein 362

increases expression

fipronil results in increased expression of ZFP362 mRNA

NCBI chr 5:141,119,073...141,153,304
Ensembl chr 5:141,119,898...141,156,716

G

zinc finger protein 365

increases expression

fipronil results in increased expression of ZFP365 mRNA

NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238

G

zinc finger protein 637

decreases expression

fipronil results in decreased expression of ZFP637 mRNA

NCBI chr 4:150,984,940...151,010,079
Ensembl chr 4:150,984,541...151,011,874

G

zinc finger protein 706

decreases expression

fipronil results in decreased expression of ZFP706 mRNA

NCBI chr 7:68,167,496...68,174,121
Ensembl chr 7:68,166,323...68,174,148

G

zinc finger protein 84

decreases expression

fipronil results in decreased expression of ZFP84 mRNA

NCBI chr 1:84,987,352...85,015,478
Ensembl chr 1:85,004,920...85,015,478
Ensembl chr 1:85,004,920...85,015,478

G

zinc finger protein, multitype 1

decreases expression

fipronil results in decreased expression of ZFPM1 mRNA

NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591

G

zona pellucida binding protein 2

increases expression

fipronil results in increased expression of ZPBP2 mRNA

NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508

G

ZPR1 zinc finger

increases expression

fipronil results in increased expression of ZPR1 mRNA

NCBI chr 8:46,564,898...46,574,719
Ensembl chr 8:46,565,146...46,574,719

G

ZW10 interacting kinetochore protein

decreases expression

fipronil results in decreased expression of ZWINT mRNA

NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19898
role	19868
application	19714
agrochemical	16885
fipronil	1161
Path 2
Term	Annotations
CHEBI ontology	19898
subatomic particle	19896
composite particle	19896
hadron	19896
baryon	19896
nucleon	19896
atomic nucleus	19896
atom	19896
main group element atom	19835
p-block element atom	19835
carbon group element atom	19774
carbon atom	19771
organic molecular entity	19771
organic molecule	19724
organic cyclic compound	19515
organic heterocyclic compound	18890
heteroarene	17169
monocyclic heteroarene	14995
azole	14515
diazole	10781
pyrazoles	2332
pyrazole	1601
1H-pyrazole	1601
1-phenylpyrazole	1161
phenylpyrazole insecticide	1161
fipronil	1161

paths to the root