Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Zc3h4 | Rat | 1,2-dichloroethane | increases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of ZC3H4 mRNA | CTD | PMID:28960355 | Zc3h4 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Zc3h4 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Zc3h4 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of ZC3H4 protein | CTD | PMID:31675489 | Zc3h4 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of ZC3H4 protein | CTD | PMID:34915118 | Zc3h4 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Decitabine affects the expression of ZC3H4 mRNA | CTD | PMID:23300844 | Zc3h4 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ZC3H4 mRNA | CTD | PMID:30047161 | Zc3h4 | Rat | acrylamide | decreases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of ZC3H4 mRNA | CTD | PMID:30807115 | Zc3h4 | Rat | acrylamide | increases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of ZC3H4 mRNA | CTD | PMID:32763439 | Zc3h4 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ZC3H4 mRNA | CTD | PMID:30047161 | Zc3h4 | Rat | arsane | affects methylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZC3H4 gene | CTD | PMID:25304211 | Zc3h4 | Rat | arsenic atom | affects methylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZC3H4 gene | CTD | PMID:25304211 | Zc3h4 | Rat | benzo[a]pyrene | increases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ZC3H4 mRNA | CTD | PMID:22228805 | Zc3h4 | Rat | benzo[a]pyrene | affects methylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ZC3H4 promoter | CTD | PMID:27901495 | Zc3h4 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20382639 | Zc3h4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZC3H4 mRNA | CTD | PMID:25181051 | Zc3h4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZC3H4 mRNA | CTD | PMID:32528016 and PMID:34947998 | Zc3h4 | Rat | bisphenol A | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ZC3H4 protein | CTD | PMID:31675489 and PMID:33376534 | Zc3h4 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of ZC3H4 mRNA | CTD | PMID:30816183 | Zc3h4 | Rat | butanal | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of ZC3H4 mRNA | CTD | PMID:26079696 | Zc3h4 | Rat | cadmium dichloride | increases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ZC3H4 mRNA | CTD | PMID:38382870 | Zc3h4 | Rat | caffeine | decreases phosphorylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ZC3H4 protein | CTD | PMID:35688186 | Zc3h4 | Rat | carbamazepine | affects expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ZC3H4 mRNA | CTD | PMID:25979313 | Zc3h4 | Rat | chlorpyrifos | decreases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ZC3H4 mRNA | CTD | PMID:37019170 | Zc3h4 | Rat | cisplatin | affects expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Cisplatin affects the expression of ZC3H4 mRNA | CTD | PMID:23300844 | Zc3h4 | Rat | cisplatin | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ZC3H4 mRNA | CTD | PMID:27392435 and PMID:27594783 | Zc3h4 | Rat | coumarin | affects phosphorylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of ZC3H4 protein | CTD | PMID:35688186 | Zc3h4 | Rat | cyclosporin A | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ZC3H4 mRNA | CTD | PMID:25562108 | Zc3h4 | Rat | decabromodiphenyl ether | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of ZC3H4 protein | CTD | PMID:31675489 | Zc3h4 | Rat | Dibutyl phosphate | affects expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ZC3H4 mRNA | CTD | PMID:37042841 | Zc3h4 | Rat | dicrotophos | increases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of ZC3H4 mRNA | CTD | PMID:28302478 | Zc3h4 | Rat | dioxygen | multiple interactions | ISO | Zc3h4 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZC3H4 mRNA | CTD | PMID:30529165 | Zc3h4 | Rat | enzyme inhibitor | multiple interactions | ISO | ZC3H4 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ZC3H4 protein | CTD | PMID:23301498 | Zc3h4 | Rat | ethanol | multiple interactions | ISO | ZC3H4 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of ZC3H4 mRNA | CTD | PMID:29432896 | Zc3h4 | Rat | ethanol | affects splicing | ISO | Zc3h4 (Mus musculus) | 6480464 | Ethanol affects the splicing of ZC3H4 mRNA | CTD | PMID:30319688 | Zc3h4 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of ZC3H4 mRNA | CTD | PMID:34044035 | Zc3h4 | Rat | formaldehyde | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ZC3H4 mRNA | CTD | PMID:20655997 | Zc3h4 | Rat | FR900359 | affects phosphorylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ZC3H4 protein | CTD | PMID:37730182 | Zc3h4 | Rat | gentamycin | affects expression | EXP | | 6480464 | Gentamicins affects the expression of ZC3H4 mRNA | CTD | PMID:33387578 | Zc3h4 | Rat | iron dichloride | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of ZC3H4 mRNA | CTD | PMID:35984750 | Zc3h4 | Rat | isobutanol | multiple interactions | ISO | ZC3H4 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of ZC3H4 mRNA | CTD | PMID:29432896 | Zc3h4 | Rat | ivermectin | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ZC3H4 protein | CTD | PMID:32959892 | Zc3h4 | Rat | lead(0) | affects expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Lead affects the expression of ZC3H4 mRNA | CTD | PMID:28903495 | Zc3h4 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ZC3H4 mRNA | CTD | PMID:30047161 | Zc3h4 | Rat | methyl methanesulfonate | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ZC3H4 mRNA | CTD | PMID:23649840 | Zc3h4 | Rat | ozone | multiple interactions | ISO | ZC3H4 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of ZC3H4 mRNA | CTD | PMID:35430440 | Zc3h4 | Rat | paracetamol | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ZC3H4 mRNA | CTD | PMID:21420995 | Zc3h4 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ZC3H4 mRNA | CTD | PMID:33387578 | Zc3h4 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of ZC3H4 mRNA | CTD | PMID:25812627 | Zc3h4 | Rat | perfluorononanoic acid | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of ZC3H4 mRNA | CTD | PMID:25812627 | Zc3h4 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ZC3H4 mRNA | CTD | PMID:25812627 | Zc3h4 | Rat | perfluorooctanoic acid | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of ZC3H4 mRNA | CTD | PMID:25812627 | Zc3h4 | Rat | potassium dichromate | decreases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of ZC3H4 mRNA | CTD | PMID:23608068 | Zc3h4 | Rat | procymidone | decreases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | procymidone results in decreased expression of ZC3H4 mRNA and procymidone results in decreased expression of ZC3H4 mRNA alternative form | CTD | PMID:35913088 | Zc3h4 | Rat | quercetin | affects phosphorylation | ISO | ZC3H4 (Homo sapiens) | 6480464 | Quercetin affects the phosphorylation of ZC3H4 protein | CTD | PMID:35688186 | Zc3h4 | Rat | sodium arsenite | increases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ZC3H4 mRNA | CTD | PMID:34032870 | Zc3h4 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of ZC3H4 mRNA | CTD | PMID:30047161 | Zc3h4 | Rat | sulforaphane | multiple interactions | ISO | Zc3h4 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of ZC3H4 mRNA | CTD | PMID:30529165 | Zc3h4 | Rat | thiram | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Thiram results in decreased expression of ZC3H4 mRNA | CTD | PMID:38568856 | Zc3h4 | Rat | titanium dioxide | decreases methylation | ISO | Zc3h4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of ZC3H4 promoter | CTD | PMID:35295148 | Zc3h4 | Rat | trichostatin A | affects expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | trichostatin A affects the expression of ZC3H4 mRNA | CTD | PMID:28542535 | Zc3h4 | Rat | troglitazone | decreases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | troglitazone results in decreased expression of ZC3H4 mRNA | CTD | PMID:28973697 | Zc3h4 | Rat | tungsten | decreases expression | ISO | Zc3h4 (Mus musculus) | 6480464 | Tungsten results in decreased expression of ZC3H4 mRNA | CTD | PMID:30912803 | Zc3h4 | Rat | urethane | increases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Urethane results in increased expression of ZC3H4 mRNA | CTD | PMID:28818685 | Zc3h4 | Rat | valproic acid | affects expression | ISO | Zc3h4 (Mus musculus) | 6480464 | Valproic Acid affects the expression of ZC3H4 mRNA | CTD | PMID:17292431 | Zc3h4 | Rat | valproic acid | decreases expression | ISO | ZC3H4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZC3H4 mRNA | CTD | PMID:29154799 | |