Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pgm2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PGM2 mRNA | CTD | PMID:22206623 | Pgm2 | Rat | 17beta-estradiol | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PGM2 mRNA | CTD | PMID:30165855 | Pgm2 | Rat | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Metribolone results in increased expression of PGM2 protein | CTD | PMID:17152098 | Pgm2 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of PGM2 mRNA | CTD | PMID:29581250 | Pgm2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Pgm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PGM2 mRNA | CTD | PMID:17101203 | Pgm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PGM2 mRNA | CTD | PMID:26232522 and PMID:34747641 | Pgm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pgm2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PGM2 mRNA | CTD | PMID:21570461 | Pgm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PGM2 mRNA | CTD | PMID:19770486 | Pgm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of PGM2 gene | CTD | PMID:21212295 | Pgm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases methylation | ISO | Pgm2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased methylation of PGM2 gene | CTD | PMID:21212295 | Pgm2 | Rat | 2,4,6-tribromophenol | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Pgm2 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of PGM2 protein | CTD | PMID:31675489 | Pgm2 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of PGM2 mRNA | CTD | PMID:31881176 | Pgm2 | Rat | acrylamide | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of PGM2 mRNA | CTD | PMID:32763439 | Pgm2 | Rat | aflatoxin B1 | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of PGM2 mRNA | CTD | PMID:27153756 | Pgm2 | Rat | antirheumatic drug | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of PGM2 mRNA | CTD | PMID:24449571 | Pgm2 | Rat | aristolochic acid A | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PGM2 mRNA | CTD | PMID:33212167 | Pgm2 | Rat | arsenous acid | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of PGM2 mRNA | CTD | PMID:29095437 | Pgm2 | Rat | arsenous acid | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PGM2 protein | CTD | PMID:25419056 | Pgm2 | Rat | arsenous acid | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of PGM2 mRNA] | CTD | PMID:29095437 | Pgm2 | Rat | atrazine | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of PGM2 mRNA | CTD | PMID:22378314 | Pgm2 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | PGM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of PGM2 gene | CTD | PMID:25435355 | Pgm2 | Rat | benzo[a]pyrene | increases methylation | ISO | PGM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PGM2 promoter | CTD | PMID:27901495 | Pgm2 | Rat | benzo[a]pyrene | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PGM2 mRNA | CTD | PMID:22228805 | Pgm2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Pgm2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PGM2 mRNA | CTD | PMID:25181051 | Pgm2 | Rat | bisphenol A | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PGM2 protein | CTD | PMID:35999755 | Pgm2 | Rat | bisphenol A | decreases methylation | ISO | PGM2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of PGM2 gene | CTD | PMID:31601247 | Pgm2 | Rat | bisphenol A | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PGM2 gene | CTD | PMID:31601247 | Pgm2 | Rat | bisphenol A | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PGM2 protein | CTD | PMID:31675489 and PMID:34186270 | Pgm2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PGM2 mRNA | CTD | PMID:34947998 | Pgm2 | Rat | Bisphenol B | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of PGM2 protein | CTD | PMID:34186270 | Pgm2 | Rat | bisphenol F | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PGM2 protein | CTD | PMID:34186270 | Pgm2 | Rat | caffeine | increases phosphorylation | ISO | PGM2 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of PGM2 protein | CTD | PMID:35688186 | Pgm2 | Rat | captan | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Captan results in increased expression of PGM2 mRNA | CTD | PMID:31558096 | Pgm2 | Rat | carbon nanotube | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of PGM2 mRNA | CTD | PMID:25554681 | Pgm2 | Rat | carmustine | affects response to substance | ISO | PGM2 (Homo sapiens) | 6480464 | PGM2 mRNA affects the susceptibility to Carmustine | CTD | PMID:16365179 | Pgm2 | Rat | CGP 52608 | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PGM2 gene] | CTD | PMID:28238834 | Pgm2 | Rat | clofibrate | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of PGM2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PGM2 mRNA] | CTD | PMID:17585979 | Pgm2 | Rat | cobalt dichloride | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of PGM2 mRNA | CTD | PMID:19320972 | Pgm2 | Rat | cyclosporin A | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PGM2 mRNA | CTD | PMID:20106945 | Pgm2 | Rat | cyclosporin A | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PGM2 mRNA | CTD | PMID:25562108 | Pgm2 | Rat | DDE | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of PGM2 mRNA | CTD | PMID:38568856 | Pgm2 | Rat | decabromodiphenyl ether | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of PGM2 protein | CTD | PMID:31675489 | Pgm2 | Rat | dextran sulfate | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of PGM2 protein | CTD | PMID:35999755 | Pgm2 | Rat | diarsenic trioxide | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of PGM2 mRNA] | CTD | PMID:29095437 | Pgm2 | Rat | diarsenic trioxide | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of PGM2 protein | CTD | PMID:25419056 | Pgm2 | Rat | diarsenic trioxide | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of PGM2 mRNA | CTD | PMID:29095437 | Pgm2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PGM2 mRNA | CTD | PMID:21266533 | Pgm2 | Rat | dicrotophos | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of PGM2 mRNA | CTD | PMID:28302478 | Pgm2 | Rat | disodium selenite | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of PGM2 mRNA | CTD | PMID:18175754 | Pgm2 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of PGM2 mRNA | CTD | PMID:21551480 | Pgm2 | Rat | dorsomorphin | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PGM2 mRNA | CTD | PMID:27188386 | Pgm2 | Rat | ethanol | affects splicing | ISO | Pgm2 (Mus musculus) | 6480464 | Ethanol affects the splicing of PGM2 mRNA | CTD | PMID:30319688 | Pgm2 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of PGM2 mRNA | CTD | PMID:23962444 | Pgm2 | Rat | fluoranthene | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of PGM2 mRNA | CTD | PMID:28329830 | Pgm2 | Rat | folpet | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | folpet results in increased expression of PGM2 mRNA | CTD | PMID:31558096 | Pgm2 | Rat | FR900359 | increases phosphorylation | ISO | PGM2 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of PGM2 protein | CTD | PMID:37730182 | Pgm2 | Rat | fulvestrant | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PGM2 gene | CTD | PMID:31601247 | Pgm2 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of PGM2 mRNA | CTD | PMID:27387713 | Pgm2 | Rat | hydrogen peroxide | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of PGM2 mRNA | CTD | PMID:18951874 | Pgm2 | Rat | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Arbutin results in increased expression of PGM2 mRNA | CTD | PMID:17103032 | Pgm2 | Rat | ivermectin | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PGM2 protein | CTD | PMID:32959892 | Pgm2 | Rat | kojic acid | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | kojic acid results in increased expression of PGM2 mRNA | CTD | PMID:16595896 | Pgm2 | Rat | lipopolysaccharide | decreases methylation | ISO | Pgm2 (Mus musculus) | 6480464 | Lipopolysaccharides results in decreased methylation of PGM2 gene | CTD | PMID:21212295 | Pgm2 | Rat | lipopolysaccharide | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of PGM2 gene | CTD | PMID:21212295 | Pgm2 | Rat | maneb | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PGM2 mRNA | CTD | PMID:36117858 | Pgm2 | Rat | metformin | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | Metformin inhibits the reaction [Arsenic Trioxide results in decreased expression of PGM2 mRNA] | CTD | PMID:29095437 | Pgm2 | Rat | nickel atom | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of PGM2 mRNA | CTD | PMID:23195993 | Pgm2 | Rat | nickel atom | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Nickel results in increased expression of PGM2 mRNA | CTD | PMID:25583101 | Pgm2 | Rat | paracetamol | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of PGM2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PGM2 mRNA] | CTD | PMID:17585979 | Pgm2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PGM2 mRNA | CTD | PMID:33387578 | Pgm2 | Rat | paracetamol | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PGM2 mRNA | CTD | PMID:21420995 | Pgm2 | Rat | paraquat | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of PGM2 mRNA | CTD | PMID:36117858 | Pgm2 | Rat | perfluorooctane-1-sulfonic acid | affects expression | ISO | Pgm2 (Mus musculus) | 6480464 | perfluorooctane sulfonic acid affects the expression of PGM2 mRNA | CTD | PMID:19429403 | Pgm2 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | Pgm2 (Mus musculus) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PGM2 protein | CTD | PMID:26178269 | Pgm2 | Rat | perfluorooctanoic acid | affects expression | ISO | Pgm2 (Mus musculus) | 6480464 | perfluorooctanoic acid affects the expression of PGM2 mRNA | CTD | PMID:19429403 | Pgm2 | Rat | perfluorooctanoic acid | multiple interactions | ISO | Pgm2 (Mus musculus) | 6480464 | Dietary Fats and Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of PGM2 mRNA] | CTD | PMID:23626681 | Pgm2 | Rat | phenylmercury acetate | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of PGM2 mRNA | CTD | PMID:26272509 | Pgm2 | Rat | phenylmercury acetate | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PGM2 mRNA | CTD | PMID:27188386 | Pgm2 | Rat | pirinixic acid | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PGM2 mRNA | CTD | PMID:19710929 | Pgm2 | Rat | pirinixic acid | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PGM2 mRNA | CTD | PMID:17426115 and PMID:18301758 | Pgm2 | Rat | quercetin | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of PGM2 mRNA | CTD | PMID:21632981 | Pgm2 | Rat | resveratrol | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PGM2 mRNA | CTD | PMID:23557933 | Pgm2 | Rat | SB 431542 | multiple interactions | ISO | PGM2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | Pgm2 | Rat | sunitinib | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of PGM2 mRNA | CTD | PMID:31533062 | Pgm2 | Rat | temozolomide | affects response to substance | ISO | PGM2 (Homo sapiens) | 6480464 | PGM2 mRNA affects the susceptibility to temozolomide | CTD | PMID:16365179 | Pgm2 | Rat | temozolomide | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of PGM2 mRNA | CTD | PMID:31758290 | Pgm2 | Rat | tert-butyl hydroperoxide | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in increased expression of PGM2 mRNA | CTD | PMID:15003993 | Pgm2 | Rat | tetrachloromethane | increases expression | ISO | Pgm2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PGM2 mRNA | CTD | PMID:31919559 | Pgm2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PGM2 mRNA | CTD | PMID:34492290 | Pgm2 | Rat | thiram | decreases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Thiram results in decreased expression of PGM2 mRNA | CTD | PMID:38568856 | Pgm2 | Rat | titanium dioxide | increases methylation | ISO | Pgm2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of PGM2 gene | CTD | PMID:35295148 | Pgm2 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of PGM2 mRNA | CTD | PMID:33387578 | Pgm2 | Rat | triphenyl phosphate | affects expression | ISO | PGM2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PGM2 mRNA | CTD | PMID:37042841 | Pgm2 | Rat | valproic acid | affects expression | ISO | PGM2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PGM2 mRNA | CTD | PMID:25979313 | Pgm2 | Rat | valproic acid | increases expression | ISO | PGM2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PGM2 mRNA | CTD | PMID:23179753 more ... | |