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Gene: Cstb (cystatin B) Rattus norvegicus
Symbol: Cstb
Name: cystatin B
Description: Predicted to have cysteine-type endopeptidase inhibitor activity and protease binding activity. Predicted to be involved in adult locomotory behavior and negative regulation of peptidase activity. Predicted to localize to cytosol; extracellular space; and nucleolus. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in Unverricht-Lundborg syndrome and progressive myoclonus epilepsy 1A. Orthologous to human CSTB (cystatin B); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CYB; cystatin B (stefin B); Cystatin beta; cystatin-B; cystatin-beta; EPM1; liver thiol proteinase inhibitor; MGC105499; stefin-B; Stfb
Homo sapiens (human) : CSTB (cystatin B)  HGNC  Alliance
Mus musculus (house mouse) : Cstb (cystatin B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cstb (cystatin B)
Pan paniscus (bonobo/pygmy chimpanzee) : CSTB (cystatin B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cstb (cystatin B)
Sus scrofa (pig) : CSTB (cystatin B)
Chlorocebus sabaeus (African green monkey) : CSTB (cystatin B)
Heterocephalus glaber (naked mole-rat) : Cstb (cystatin B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02010,966,357 - 10,968,399 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2010,966,331 - 10,968,432 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,137,896 - 13,139,938 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,576,664 - 10,578,706 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12010,576,891 - 10,578,923 (-)NCBI
Celera2011,756,111 - 11,758,153 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cstb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2435
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.