Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fbxw5 | Rat | (S)-nicotine | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Nicotine results in decreased expression of FBXW5 mRNA | CTD | PMID:17997037 | Fbxw5 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Fbxw5 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBXW5 mRNA | CTD | PMID:22206623 | Fbxw5 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of FBXW5 mRNA | CTD | PMID:22206623 | Fbxw5 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of FBXW5 mRNA | CTD | PMID:17942748 | Fbxw5 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Fbxw5 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FBXW5 mRNA | CTD | PMID:17942748 | Fbxw5 | Rat | 17beta-estradiol | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA | CTD | PMID:20823114 | Fbxw5 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Fbxw5 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | Fbxw5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Fbxw5 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FBXW5 mRNA | CTD | PMID:17942748 | Fbxw5 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FBXW5 mRNA | CTD | PMID:33387578 | Fbxw5 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of FBXW5 mRNA | CTD | PMID:20188158 | Fbxw5 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | Fbxw5 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of FBXW5 mRNA | CTD | PMID:36041667 | Fbxw5 | Rat | acrylamide | increases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Acrylamide results in increased expression of FBXW5 mRNA | CTD | PMID:30807115 | Fbxw5 | Rat | arsenous acid | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of FBXW5 mRNA | CTD | PMID:35676786 | Fbxw5 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FBXW5 mRNA | CTD | PMID:25181051 | Fbxw5 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of FBXW5 mRNA | CTD | PMID:36041667 | Fbxw5 | Rat | bisphenol A | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | Fbxw5 | Rat | bisphenol F | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | Fbxw5 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of FBXW5 mRNA | CTD | PMID:36041667 | Fbxw5 | Rat | bucladesine | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA | CTD | PMID:20823114 | Fbxw5 | Rat | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of FBXW5 mRNA | CTD | PMID:19167457 | Fbxw5 | Rat | chlorpyrifos | increases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of FBXW5 mRNA | CTD | PMID:37019170 | Fbxw5 | Rat | cobalt atom | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | dexamethasone | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | Fbxw5 | Rat | diarsenic trioxide | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of FBXW5 mRNA | CTD | PMID:35676786 | Fbxw5 | Rat | diazinon | increases methylation | ISO | FBXW5 (Homo sapiens) | 6480464 | Diazinon results in increased methylation of FBXW5 gene | CTD | PMID:22964155 | Fbxw5 | Rat | Dibutyl phosphate | affects expression | ISO | FBXW5 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of FBXW5 mRNA | CTD | PMID:37042841 | Fbxw5 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FBXW5 mRNA | CTD | PMID:21266533 | Fbxw5 | Rat | epoxiconazole | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of FBXW5 mRNA | CTD | PMID:35436446 | Fbxw5 | Rat | ethanol | affects splicing | ISO | Fbxw5 (Mus musculus) | 6480464 | Ethanol affects the splicing of FBXW5 mRNA | CTD | PMID:30319688 | Fbxw5 | Rat | fenthion | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Fenthion results in decreased expression of FBXW5 mRNA | CTD | PMID:34813904 | Fbxw5 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of FBXW5 mRNA | CTD | PMID:23962444 | Fbxw5 | Rat | folic acid | multiple interactions | ISO | Fbxw5 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBXW5 mRNA | CTD | PMID:22206623 | Fbxw5 | Rat | formaldehyde | increases expression | ISO | FBXW5 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of FBXW5 mRNA | CTD | PMID:18045764 | Fbxw5 | Rat | FR900359 | decreases phosphorylation | ISO | FBXW5 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FBXW5 protein | CTD | PMID:37730182 | Fbxw5 | Rat | hypochlorous acid | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of FBXW5 mRNA | CTD | PMID:19376150 | Fbxw5 | Rat | indometacin | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | Fbxw5 | Rat | irinotecan | increases expression | ISO | FBXW5 (Homo sapiens) | 6480464 | Irinotecan results in increased expression of FBXW5 mRNA | CTD | PMID:20185912 | Fbxw5 | Rat | iron atom | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | iron(0) | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | isobutanol | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of FBXW5 mRNA | CTD | PMID:29432896 | Fbxw5 | Rat | kainic acid | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Kainic Acid results in decreased expression of FBXW5 mRNA | CTD | PMID:17997037 | Fbxw5 | Rat | medroxyprogesterone acetate | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA | CTD | PMID:20823114 | Fbxw5 | Rat | methidathion | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | methidathion results in decreased expression of FBXW5 mRNA | CTD | PMID:34813904 | Fbxw5 | Rat | methyl methanesulfonate | increases expression | ISO | FBXW5 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of FBXW5 mRNA | CTD | PMID:23649840 | Fbxw5 | Rat | nickel atom | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA and [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | nicotine | decreases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | Nicotine results in decreased expression of FBXW5 mRNA | CTD | PMID:17997037 | Fbxw5 | Rat | ozone | multiple interactions | ISO | FBXW5 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of FBXW5 mRNA | CTD | PMID:35430440 | Fbxw5 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of FBXW5 mRNA | CTD | PMID:33387578 | Fbxw5 | Rat | pirinixic acid | increases expression | ISO | Fbxw5 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of FBXW5 mRNA | CTD | PMID:18301758 | Fbxw5 | Rat | sodium arsenite | decreases expression | ISO | FBXW5 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of FBXW5 mRNA | CTD | PMID:38568856 | Fbxw5 | Rat | sodium tungstate | decreases expression | EXP | | 6480464 | sodium tungstate(VI) results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | sunitinib | increases expression | ISO | FBXW5 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of FBXW5 mRNA | CTD | PMID:31533062 | Fbxw5 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of FBXW5 mRNA | CTD | PMID:34492290 | Fbxw5 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of FBXW5 mRNA | CTD | PMID:33387578 | Fbxw5 | Rat | tungsten | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA and [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | Fbxw5 | Rat | valproic acid | increases methylation | ISO | FBXW5 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of FBXW5 gene | CTD | PMID:29154799 | Fbxw5 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of FBXW5 mRNA | CTD | PMID:21318169 | |