![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | decreases expression | ISO | RGD:1313823 | 6480464 | Nicotine results in decreased expression of FBXW5 mRNA | CTD | PMID:17997037 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1313823 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBXW5 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1313823 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of FBXW5 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1313823 | 6480464 | Ethinyl Estradiol results in increased expression of FBXW5 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1313823 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FBXW5 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:1313822 | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA | CTD | PMID:20823114 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | RGD:1313823 | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1313823 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of FBXW5 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FBXW5 mRNA | CTD | PMID:33387578 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1313823 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of FBXW5 mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1313822 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of FBXW5 mRNA | CTD | PMID:36041667 | acrylamide | increases expression | ISO | RGD:1313823 | 6480464 | Acrylamide results in increased expression of FBXW5 mRNA | CTD | PMID:30807115 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FBXW5 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of FBXW5 mRNA | CTD | PMID:36041667 | bisphenol A | multiple interactions | ISO | RGD:1313822 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | ISO | RGD:1313822 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of FBXW5 mRNA | CTD | PMID:36041667 | bucladesine | multiple interactions | ISO | RGD:1313822 | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA | CTD | PMID:20823114 | C60 fullerene | increases expression | EXP | | 6480464 | fullerene C60 results in increased expression of FBXW5 mRNA | CTD | PMID:19167457 | cobalt atom | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | dexamethasone | multiple interactions | ISO | RGD:1313822 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | diazinon | increases methylation | ISO | RGD:1313822 | 6480464 | Diazinon results in increased methylation of FBXW5 gene | CTD | PMID:22964155 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of FBXW5 mRNA | CTD | PMID:21266533 | epoxiconazole | decreases expression | ISO | RGD:1313823 | 6480464 | epoxiconazole results in decreased expression of FBXW5 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | ISO | RGD:1313823 | 6480464 | Ethanol affects the splicing of FBXW5 mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | RGD:1313823 | 6480464 | Fenthion results in decreased expression of FBXW5 mRNA | CTD | PMID:34813904 | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of FBXW5 mRNA | CTD | PMID:23962444 | folic acid | multiple interactions | ISO | RGD:1313823 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FBXW5 mRNA | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | RGD:1313822 | 6480464 | Formaldehyde results in increased expression of FBXW5 mRNA | CTD | PMID:18045764 | hypochlorous acid | decreases expression | ISO | RGD:1313823 | 6480464 | Hypochlorous Acid results in decreased expression of FBXW5 mRNA | CTD | PMID:19376150 | indometacin | multiple interactions | ISO | RGD:1313822 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXW5 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FBXW5 mRNA | CTD | PMID:28628672 | irinotecan | increases expression | ISO | RGD:1313822 | 6480464 | Irinotecan results in increased expression of FBXW5 mRNA | CTD | PMID:20185912 | iron atom | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | iron(0) | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | isobutanol | multiple interactions | ISO | RGD:1313822 | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of FBXW5 mRNA | CTD | PMID:29432896 | kainic acid | decreases expression | ISO | RGD:1313823 | 6480464 | Kainic Acid results in decreased expression of FBXW5 mRNA | CTD | PMID:17997037 | medroxyprogesterone acetate | multiple interactions | ISO | RGD:1313822 | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA | CTD | PMID:20823114 | methidathion | decreases expression | ISO | RGD:1313823 | 6480464 | methidathion results in decreased expression of FBXW5 mRNA | CTD | PMID:34813904 | methyl methanesulfonate | increases expression | ISO | RGD:1313822 | 6480464 | Methyl Methanesulfonate results in increased expression of FBXW5 mRNA | CTD | PMID:23649840 | nickel atom | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA, [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | nicotine | decreases expression | ISO | RGD:1313823 | 6480464 | Nicotine results in decreased expression of FBXW5 mRNA | CTD | PMID:17997037 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of FBXW5 mRNA | CTD | PMID:33387578 | pirinixic acid | increases expression | ISO | RGD:1313823 | 6480464 | pirinixic acid results in increased expression of FBXW5 mRNA | CTD | PMID:18301758 | sodium tungstate | decreases expression | EXP | | 6480464 | sodium tungstate(VI) results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | sunitinib | increases expression | ISO | RGD:1313822 | 6480464 | Sunitinib results in increased expression of FBXW5 mRNA | CTD | PMID:31533062 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of FBXW5 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of FBXW5 mRNA | CTD | PMID:33387578 | tungsten | multiple interactions | EXP | | 6480464 | [Tungsten co-treated with Nickel co-treated with Cobalt] results in decreased expression of FBXW5 mRNA, [Tungsten co-treated with Nickel co-treated with Iron] results in decreased expression of FBXW5 mRNA | CTD | PMID:24619124 | valproic acid | increases methylation | ISO | RGD:1313822 | 6480464 | Valproic Acid results in increased methylation of FBXW5 gene | CTD | PMID:29154799 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of FBXW5 mRNA | CTD | PMID:21318169 | |