Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: FBXW5 (F-box and WD repeat domain containing 5) Homo sapiens
Symbol: FBXW5
Name: F-box and WD repeat domain containing 5
Description: Exhibits protein kinase binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of centrosome duplication. Localizes to the Cul4-RING E3 ubiquitin ligase complex; SCF ubiquitin ligase complex; and cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp434B205; F-box and WD-40 domain protein 5; F-box and WD-40 domain-containing protein 5; F-box/WD repeat-containing protein 5; Fbw5; MGC20962; RP11-229P13.10; WD repeat-containing F-box protein FBW5
Mus musculus (house mouse) : Fbxw5 (F-box and WD-40 domain protein 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxw5 (F-box and WD repeat domain containing 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw5 (F-box and WD repeat domain containing 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW5 (F-box and WD repeat domain containing 5)
Canis lupus familiaris (dog) : FBXW5 (F-box and WD repeat domain containing 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw5 (F-box and WD repeat domain containing 5)
Sus scrofa (pig) : FBXW5 (F-box and WD repeat domain containing 5)
Chlorocebus sabaeus (African green monkey) : FBXW5 (F-box and WD repeat domain containing 5)
Heterocephalus glaber (naked mole-rat) : Fbxw5 (F-box and WD repeat domain containing 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl9136,940,435 - 136,944,738 (-)EnsemblGRCh38hg38GRCh38
GRCh389136,940,435 - 136,944,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379139,834,885 - 139,839,298 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,954,708 - 138,958,994 (-)NCBINCBI36hg18NCBI36
Celera9110,349,118 - 110,353,404 (-)NCBI
Cytogenetic Map9q34.3NCBI
HuRef9109,294,320 - 109,297,993 (-)NCBIHuRef
CHM1_19139,983,564 - 139,987,884 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXW5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313822
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.