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Gene: Fbxw5 (F-box and WD-40 domain protein 5) Mus musculus
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Symbol: Fbxw5
Name: F-box and WD-40 domain protein 5
Description: Predicted to have protein kinase binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of mitotic nuclear division. Localizes to the SCF ubiquitin ligase complex. Is expressed in central nervous system; embryo; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FBXW5 (F-box and WD repeat domain containing 5); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI159739; F-box and WD-40 domain-containing protein 5; F-box protein Fbw5; F-box/WD repeat-containing protein 5; Fbw5
Orthologs:
Homo sapiens (human) : FBXW5 (F-box and WD repeat domain containing 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxw5 (F-box and WD repeat domain containing 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw5 (F-box and WD repeat domain containing 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW5 (F-box and WD repeat domain containing 5)
Canis lupus familiaris (dog) : FBXW5 (F-box and WD repeat domain containing 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw5 (F-box and WD repeat domain containing 5)
Sus scrofa (pig) : FBXW5 (F-box and WD repeat domain containing 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38225,500,750 - 25,505,470 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37225,356,298 - 25,360,990 (+)NCBIGRCm37mm9NCBIm37
MGSCv36225,322,787 - 25,327,479 (+)NCBImm8
Celera225,228,300 - 25,232,992 (+)NCBICelera
Cytogenetic Map2 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fbxw5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313823
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.