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Gene: Fbxw5 (F-box and WD-40 domain protein 5) Mus musculus
Symbol: Fbxw5
Name: F-box and WD-40 domain protein 5
Description: Predicted to have protein kinase binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and regulation of mitotic nuclear division. Localizes to the SCF ubiquitin ligase complex. Is expressed in central nervous system; embryo; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human FBXW5 (F-box and WD repeat domain containing 5); INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI159739; F-box and WD-40 domain-containing protein 5; F-box protein Fbw5; F-box/WD repeat-containing protein 5; Fbw5
Homo sapiens (human) : FBXW5 (F-box and WD repeat domain containing 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fbxw5 (F-box and WD repeat domain containing 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxw5 (F-box and WD repeat domain containing 5)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXW5 (F-box and WD repeat domain containing 5)
Canis lupus familiaris (dog) : FBXW5 (F-box and WD repeat domain containing 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxw5 (F-box and WD repeat domain containing 5)
Sus scrofa (pig) : FBXW5 (F-box and WD repeat domain containing 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38225,500,750 - 25,505,470 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37225,356,298 - 25,360,990 (+)NCBIGRCm37mm9NCBIm37
MGSCv36225,322,787 - 25,327,479 (+)NCBImm8
Celera225,228,300 - 25,232,992 (+)NCBICelera
Cytogenetic Map2 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fbxw5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313823
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.