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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | RGD:1332200 | 6480464 | ethylene dichloride results in decreased expression of TPD52L2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1332200 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TPD52L2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of TPD52L2 mRNA | CTD | PMID:29097150 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1332200 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TPD52L2 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1332200 | 6480464 | Tetrachlorodibenzodioxin affects the expression of TPD52L2 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of TPD52L2 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of TPD52L2 mRNA | CTD | PMID:21346803 | 2-amino-14,16-dimethyloctadecan-3-ol | decreases expression | ISO | RGD:1352243 | 6480464 | 2-amino-14, 16-dimethyloctadecan-3-ol results in decreased expression of TPD52L2 protein | CTD | PMID:32044396 | 2-methylcholine | affects expression | ISO | RGD:1352243 | 6480464 | beta-methylcholine affects the expression of TPD52L2 mRNA | CTD | PMID:21179406 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1352243 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1332200 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of TPD52L2 mRNA | CTD | PMID:18648102 | 4-tert-Octylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of TPD52L2 mRNA | CTD | PMID:17011747 | 4-tert-Octylphenol | decreases expression | EXP | | 6480464 | 4-tert-octylphenol results in decreased expression of TPD52L2 mRNA | CTD | PMID:17011747 | acetylsalicylic acid | decreases expression | ISO | RGD:1352243 | 6480464 | Aspirin results in decreased expression of TPD52L2 mRNA | CTD | PMID:15928584 | acrylamide | increases expression | ISO | RGD:1352243 | 6480464 | Acrylamide results in increased expression of TPD52L2 mRNA | CTD | PMID:32763439 | aristolochic acid | increases expression | ISO | RGD:1352243 | 6480464 | aristolochic acid I results in increased expression of TPD52L2 mRNA | CTD | PMID:33212167 | arsane | increases methylation | ISO | RGD:1352243 | 6480464 | Arsenic results in increased methylation of TPD52L2 promoter | CTD | PMID:21291286 | arsenic atom | increases methylation | ISO | RGD:1352243 | 6480464 | Arsenic results in increased methylation of TPD52L2 promoter | CTD | PMID:21291286 | arsenite(3-) | increases methylation | ISO | RGD:1352243 | 6480464 | arsenite results in increased methylation of TPD52L2 promoter | CTD | PMID:23974009 | arsenous acid | increases expression | ISO | RGD:1352243 | 6480464 | Arsenic Trioxide results in increased expression of TPD52L2 mRNA | CTD | PMID:20458559 | atrazine | decreases expression | ISO | RGD:1352243 | 6480464 | Atrazine results in decreased expression of TPD52L2 mRNA | CTD | PMID:22378314 | benzene | increases expression | ISO | RGD:1352243 | 6480464 | Benzene results in increased expression of TPD52L2 mRNA | CTD | PMID:19162166 | benzo[a]pyrene | increases expression | ISO | RGD:1332200 | 6480464 | Benzo(a)pyrene results in increased expression of TPD52L2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGD:1352243 | 6480464 | Benzo(a)pyrene results in increased expression of TPD52L2 mRNA | CTD | PMID:26238291 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TPD52L2 mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases expression | ISO | RGD:1332200 | 6480464 | bisphenol A results in increased expression of TPD52L2 mRNA | CTD | PMID:33221593 | bisphenol A | decreases methylation | ISO | RGD:1332200 | 6480464 | bisphenol A results in decreased methylation of TPD52L2 promoter | CTD | PMID:27312807 | bisphenol F | multiple interactions | ISO | RGD:1352243 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of TPD52L2 mRNA | CTD | PMID:21297351 | carbon nanotube | increases expression | ISO | RGD:1332200 | 6480464 | Nanotubes, Carbon results in increased expression of TPD52L2 mRNA | CTD | PMID:25554681 | cyclosporin A | increases expression | ISO | RGD:1352243 | 6480464 | Cyclosporine results in increased expression of TPD52L2 mRNA | CTD | PMID:20106945, PMID:25562108 | dexamethasone | multiple interactions | ISO | RGD:1352243 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | RGD:1352243 | 6480464 | Arsenic Trioxide results in increased expression of TPD52L2 mRNA | CTD | PMID:20458559 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of TPD52L2 mRNA | CTD | PMID:17011747 | enzyme inhibitor | multiple interactions | ISO | RGD:1352243 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TPD52L2 protein | CTD | PMID:23301498 | fenthion | decreases expression | ISO | RGD:1332200 | 6480464 | Fenthion results in decreased expression of TPD52L2 mRNA | CTD | PMID:34813904 | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of TPD52L2 mRNA | CTD | PMID:34044035 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TPD52L2 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1332200 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TPD52L2 mRNA | CTD | PMID:22206623 | hexadecanoic acid | increases phosphorylation | ISO | RGD:1352243 | 6480464 | Palmitic Acid results in increased phosphorylation of TPD52L2 protein | CTD | PMID:28073184 | indometacin | multiple interactions | ISO | RGD:1352243 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | isobutanol | multiple interactions | ISO | RGD:1352243 | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which affects the expression of TPD52L2 mRNA | CTD | PMID:29432896 | ivermectin | decreases expression | ISO | RGD:1352243 | 6480464 | Ivermectin results in decreased expression of TPD52L2 protein | CTD | PMID:32959892 | lead(0) | affects splicing | ISO | RGD:1352243 | 6480464 | Lead affects the splicing of TPD52L2 mRNA | CTD | PMID:28903495 | lead(2+) | affects splicing | ISO | RGD:1352243 | 6480464 | Lead affects the splicing of TPD52L2 mRNA | CTD | PMID:28903495 | p-tert-Amylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of TPD52L2 mRNA | CTD | PMID:17011747 | p-tert-Amylphenol | decreases expression | EXP | | 6480464 | 4-tert-octylphenol results in decreased expression of TPD52L2 mRNA | CTD | PMID:17011747 | paracetamol | affects expression | ISO | RGD:1332200 | 6480464 | Acetaminophen affects the expression of TPD52L2 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TPD52L2 mRNA | CTD | PMID:33387578 | phenethyl isothiocyanate | affects binding | ISO | RGD:1352243 | 6480464 | TPD52L2 protein binds to phenethyl isothiocyanate | CTD | PMID:21838287 | pirinixic acid | decreases expression | ISO | RGD:1332200 | 6480464 | pirinixic acid results in decreased expression of TPD52L2 mRNA | CTD | PMID:18445702 | pyrimidifen | decreases expression | ISO | RGD:1352243 | 6480464 | pyrimidifen results in decreased expression of TPD52L2 mRNA | CTD | PMID:33512557 | rotenone | decreases expression | ISO | RGD:1352243 | 6480464 | Rotenone results in decreased expression of TPD52L2 mRNA | CTD | PMID:33512557 | silver atom | decreases expression | ISO | RGD:1332200 | 6480464 | Silver results in decreased expression of TPD52L2 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:1332200 | 6480464 | Silver results in decreased expression of TPD52L2 mRNA | CTD | PMID:27131904 | testosterone enanthate | affects expression | ISO | RGD:1352243 | 6480464 | testosterone enanthate affects the expression of TPD52L2 mRNA | CTD | PMID:17440010 | Tributyltin oxide | increases phosphorylation | ISO | RGD:1332200 | 6480464 | bis(tri-n-butyltin)oxide results in increased phosphorylation of TPD52L2 protein | CTD | PMID:22174045 | triptonide | increases expression | ISO | RGD:1332200 | 6480464 | triptonide results in increased expression of TPD52L2 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | RGD:1352243 | 6480464 | Valproic Acid results in increased methylation of TPD52L2 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | RGD:1352243 | 6480464 | Valproic Acid results in increased expression of TPD52L2 mRNA | CTD | PMID:23179753 | |