Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tpd52l2 | Rat | 1,2-dichloroethane | decreases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TPD52L2 mRNA | CTD | PMID:28960355 | Tpd52l2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tpd52l2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TPD52L2 mRNA | CTD | PMID:22206623 | Tpd52l2 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of TPD52L2 mRNA | CTD | PMID:29097150 | Tpd52l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TPD52L2 mRNA | CTD | PMID:19465110 | Tpd52l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TPD52L2 mRNA | CTD | PMID:21570461 | Tpd52l2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of TPD52L2 mRNA | CTD | PMID:21346803 | Tpd52l2 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of TPD52L2 mRNA | CTD | PMID:21346803 | Tpd52l2 | Rat | 2-amino-14,16-dimethyloctadecan-3-ol | decreases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of TPD52L2 protein | CTD | PMID:32044396 | Tpd52l2 | Rat | 2-methylcholine | affects expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of TPD52L2 mRNA | CTD | PMID:21179406 | Tpd52l2 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of TPD52L2 protein | CTD | PMID:34915118 | Tpd52l2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | Tpd52l2 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of TPD52L2 mRNA | CTD | PMID:18648102 | Tpd52l2 | Rat | 4-tert-Octylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of TPD52L2 mRNA | CTD | PMID:17011747 | Tpd52l2 | Rat | 4-tert-Octylphenol | decreases expression | EXP | | 6480464 | 4-tert-octylphenol results in decreased expression of TPD52L2 mRNA | CTD | PMID:17011747 | Tpd52l2 | Rat | acetylsalicylic acid | decreases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Aspirin results in decreased expression of TPD52L2 mRNA | CTD | PMID:15928584 | Tpd52l2 | Rat | acrylamide | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TPD52L2 mRNA | CTD | PMID:32763439 | Tpd52l2 | Rat | aristolochic acid A | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TPD52L2 mRNA | CTD | PMID:33212167 | Tpd52l2 | Rat | arsane | increases methylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of TPD52L2 promoter | CTD | PMID:21291286 | Tpd52l2 | Rat | arsenic atom | increases methylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of TPD52L2 promoter | CTD | PMID:21291286 | Tpd52l2 | Rat | arsenite(3-) | increases methylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | arsenite results in increased methylation of TPD52L2 promoter | CTD | PMID:23974009 | Tpd52l2 | Rat | arsenous acid | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TPD52L2 mRNA | CTD | PMID:20458559 | Tpd52l2 | Rat | atrazine | decreases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of TPD52L2 mRNA | CTD | PMID:22378314 | Tpd52l2 | Rat | benzene | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Benzene results in increased expression of TPD52L2 mRNA | CTD | PMID:19162166 | Tpd52l2 | Rat | benzo[a]pyrene | increases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TPD52L2 mRNA | CTD | PMID:22228805 | Tpd52l2 | Rat | benzo[a]pyrene | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of TPD52L2 mRNA | CTD | PMID:26238291 | Tpd52l2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TPD52L2 mRNA | CTD | PMID:25181051 more ... | Tpd52l2 | Rat | bisphenol A | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TPD52L2 protein | CTD | PMID:34186270 and PMID:37567409 | Tpd52l2 | Rat | bisphenol A | increases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TPD52L2 mRNA | CTD | PMID:33221593 | Tpd52l2 | Rat | bisphenol A | decreases methylation | ISO | Tpd52l2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of TPD52L2 promoter | CTD | PMID:27312807 | Tpd52l2 | Rat | Bisphenol B | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of TPD52L2 protein | CTD | PMID:34186270 | Tpd52l2 | Rat | bisphenol F | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | Tpd52l2 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of TPD52L2 mRNA | CTD | PMID:21297351 | Tpd52l2 | Rat | caffeine | affects phosphorylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of TPD52L2 protein | CTD | PMID:35688186 | Tpd52l2 | Rat | carbon nanotube | increases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of TPD52L2 mRNA | CTD | PMID:25554681 | Tpd52l2 | Rat | coumarin | increases phosphorylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of TPD52L2 protein | CTD | PMID:35688186 | Tpd52l2 | Rat | cyclosporin A | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TPD52L2 mRNA | CTD | PMID:20106945 and PMID:25562108 | Tpd52l2 | Rat | dexamethasone | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | Tpd52l2 | Rat | diarsenic trioxide | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TPD52L2 mRNA | CTD | PMID:20458559 | Tpd52l2 | Rat | Dibutyl phosphate | affects expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TPD52L2 mRNA | CTD | PMID:37042841 | Tpd52l2 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of TPD52L2 mRNA | CTD | PMID:17011747 | Tpd52l2 | Rat | enzyme inhibitor | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TPD52L2 protein | CTD | PMID:23301498 | Tpd52l2 | Rat | fenthion | decreases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Fenthion results in decreased expression of TPD52L2 mRNA | CTD | PMID:34813904 | Tpd52l2 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of TPD52L2 mRNA | CTD | PMID:34044035 | Tpd52l2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TPD52L2 mRNA | CTD | PMID:24136188 | Tpd52l2 | Rat | folic acid | multiple interactions | ISO | Tpd52l2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TPD52L2 mRNA | CTD | PMID:22206623 | Tpd52l2 | Rat | FR900359 | affects phosphorylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TPD52L2 protein | CTD | PMID:37730182 | Tpd52l2 | Rat | hexadecanoic acid | increases phosphorylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of TPD52L2 protein | CTD | PMID:28073184 | Tpd52l2 | Rat | indometacin | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TPD52L2 mRNA | CTD | PMID:28628672 | Tpd52l2 | Rat | isobutanol | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which affects the expression of TPD52L2 mRNA | CTD | PMID:29432896 | Tpd52l2 | Rat | ivermectin | decreases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TPD52L2 protein | CTD | PMID:32959892 | Tpd52l2 | Rat | lead(0) | affects splicing | ISO | TPD52L2 (Homo sapiens) | 6480464 | Lead affects the splicing of TPD52L2 mRNA | CTD | PMID:28903495 | Tpd52l2 | Rat | ozone | multiple interactions | ISO | Tpd52l2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of TPD52L2 mRNA | CTD | PMID:34911549 | Tpd52l2 | Rat | ozone | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of TPD52L2 mRNA | CTD | PMID:35430440 | Tpd52l2 | Rat | p-tert-Amylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of TPD52L2 mRNA | CTD | PMID:17011747 | Tpd52l2 | Rat | p-tert-Amylphenol | decreases expression | EXP | | 6480464 | 4-tert-octylphenol results in decreased expression of TPD52L2 mRNA | CTD | PMID:17011747 | Tpd52l2 | Rat | paracetamol | affects expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TPD52L2 mRNA | CTD | PMID:17562736 | Tpd52l2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TPD52L2 mRNA | CTD | PMID:33387578 | Tpd52l2 | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of TPD52L2 mRNA | CTD | PMID:37995155 | Tpd52l2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tpd52l2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of TPD52L2 mRNA | CTD | PMID:36331819 | Tpd52l2 | Rat | phenethyl isothiocyanate | affects binding | ISO | TPD52L2 (Homo sapiens) | 6480464 | TPD52L2 protein binds to phenethyl isothiocyanate | CTD | PMID:21838287 | Tpd52l2 | Rat | pirinixic acid | decreases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TPD52L2 mRNA | CTD | PMID:18445702 | Tpd52l2 | Rat | pyrimidifen | decreases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | pyrimidifen results in decreased expression of TPD52L2 mRNA | CTD | PMID:33512557 | Tpd52l2 | Rat | rotenone | decreases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TPD52L2 mRNA | CTD | PMID:33512557 | Tpd52l2 | Rat | SB 431542 | multiple interactions | ISO | TPD52L2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of TPD52L2 protein | CTD | PMID:37664457 | Tpd52l2 | Rat | silver atom | decreases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Silver results in decreased expression of TPD52L2 mRNA | CTD | PMID:27131904 | Tpd52l2 | Rat | silver(0) | decreases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | Silver results in decreased expression of TPD52L2 mRNA | CTD | PMID:27131904 | Tpd52l2 | Rat | sodium arsenite | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TPD52L2 mRNA | CTD | PMID:38568856 | Tpd52l2 | Rat | testosterone enanthate | affects expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of TPD52L2 mRNA | CTD | PMID:17440010 | Tpd52l2 | Rat | Tributyltin oxide | increases phosphorylation | ISO | Tpd52l2 (Mus musculus) | 6480464 | bis(tri-n-butyltin)oxide results in increased phosphorylation of TPD52L2 protein | CTD | PMID:22174045 | Tpd52l2 | Rat | triphenyl phosphate | affects expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TPD52L2 mRNA | CTD | PMID:37042841 | Tpd52l2 | Rat | triptonide | increases expression | ISO | Tpd52l2 (Mus musculus) | 6480464 | triptonide results in increased expression of TPD52L2 mRNA | CTD | PMID:33045310 | Tpd52l2 | Rat | valproic acid | increases methylation | ISO | TPD52L2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TPD52L2 gene | CTD | PMID:29154799 | Tpd52l2 | Rat | valproic acid | increases expression | ISO | TPD52L2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TPD52L2 mRNA | CTD | PMID:23179753 | |