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Gene: Marchf6 (membrane associated ring-CH-type finger 6) Rattus norvegicus
Symbol: Marchf6
Name: membrane associated ring-CH-type finger 6
RGD ID: 1565757
Description: Predicted to have ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and ubiquitin-specific protease binding activity. Predicted to be involved in protein K48-linked ubiquitination and ubiquitin-dependent ERAD pathway. Predicted to localize to endoplasmic reticulum and integral component of endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 3. Orthologous to human MARCHF6 (membrane associated ring-CH-type finger 6); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase MARCH6; LOC294862; March6; membrane-associated ring finger (C3HC4) 6; membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase; RGD1310927; RGD1565757; similar to KIAA0597 protein
Homo sapiens (human) : MARCHF6 (membrane associated ring-CH-type finger 6)  HGNC  Alliance
Mus musculus (house mouse) : Marchf6 (membrane associated ring-CH-type finger 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Marchf6 (membrane associated ring-CH-type finger 6)
Pan paniscus (bonobo/pygmy chimpanzee) : MARCHF6 (membrane associated ring-CH-type finger 6)
Canis lupus familiaris (dog) : MARCHF6 (membrane associated ring-CH-type finger 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Marchf6 (membrane associated ring-CH-type finger 6)
Sus scrofa (pig) : MARCHF6 (membrane associated ring-CH-type finger 6)
Chlorocebus sabaeus (African green monkey) : MARCHF6 (membrane associated ring-CH-type finger 6)
Heterocephalus glaber (naked mole-rat) : Marchf6 (membrane associated ring-CH-type finger 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0284,533,546 - 84,608,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl284,536,669 - 84,608,712 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02104,206,630 - 104,281,918 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4283,544,604 - 83,622,254 (-)NCBIRGSC3.4rn4RGSC3.4
Celera277,979,979 - 78,056,887 (-)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Marchf6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565757
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.