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Gene: Marchf6 (membrane associated ring-CH-type finger 6) Rattus norvegicus
Symbol: Marchf6
Name: membrane associated ring-CH-type finger 6
Description: Predicted to have ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and ubiquitin-specific protease binding activity. Predicted to be involved in protein K48-linked ubiquitination and ubiquitin-dependent ERAD pathway. Predicted to localize to the endoplasmic reticulum and integral component of endoplasmic reticulum membrane. Orthologous to human MARCHF6 (membrane associated ring-CH-type finger 6); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 4,4'-diaminodiphenylmethane; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase MARCH6; LOC294862; March6; membrane-associated ring finger (C3HC4) 6; membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase; RGD1310927; RGD1565757; similar to KIAA0597 protein
Homo sapiens (human) : MARCHF6 (membrane associated ring-CH-type finger 6)  HGNC  Alliance
Mus musculus (house mouse) : March6 (membrane-associated ring finger (C3HC4) 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Marchf6 (membrane associated ring-CH-type finger 6)
Pan paniscus (bonobo/pygmy chimpanzee) : MARCHF6 (membrane associated ring-CH-type finger 6)
Canis lupus familiaris (dog) : MARCHF6 (membrane associated ring-CH-type finger 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Marchf6 (membrane associated ring-CH-type finger 6)
Sus scrofa (pig) : MARCHF6 (membrane associated ring-CH-type finger 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0284,533,546 - 84,608,743 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl284,536,669 - 84,608,712 (-)Ensembl
Rnor_5.02104,206,630 - 104,281,918 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4283,544,604 - 83,622,254 (-)NCBIRGSC3.4rn4RGSC3.4
Celera277,979,979 - 78,056,887 (-)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Marchf6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565757
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.