Gene: Arhgef28 (Rho guanine nucleotide exchange factor 28) Rattus norvegicus
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Symbol: Arhgef28
Name: Rho guanine nucleotide exchange factor 28
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN central nervous system neuron axonogenesis (ortholog); neurofilament cytoskeleton organization (ortholog); FOUND IN cytoplasm (inferred); plasma membrane (inferred); INTERACTS WITH acrylamide; bisphenol A; C60 fullerene
AGR Description: Predicted to have guanyl-nucleotide exchange factor activity; predicted to be involved in central nervous system neuron axonogenesis and neurofilament cytoskeleton organization; predicted to localize to the cytoplasm and plasma membrane; orthologous to human ARHGEF28 (Rho guanine nucleotide exchange factor 28).
Merged Description: Predicted to have guanyl-nucleotide exchange factor activity; predicted to be involved in central nervous system neuron axonogenesis and neurofilament cytoskeleton organization; predicted to localize to the cytoplasm and plasma membrane; orthologous to human ARHGEF28 (Rho guanine nucleotide exchange factor 28); INTERACTS WITH acrylamide; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 190 kDa guanine nucleotide exchange factor; LOC361882; p190-RhoGEF; p190RhoGEF; Rgnef; rho guanine nucleotide exchange factor; Rho guanine nucleotide exchange factor (GEF) 28; Rho-guanine nucleotide exchange factor
Orthologs:
Homo sapiens (human) : ARHGEF28 (Rho guanine nucleotide exchange factor 28)  HGNC  Alliance
Mus musculus (house mouse) : Arhgef28 (Rho guanine nucleotide exchange factor (GEF) 28)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef28 (Rho guanine nucleotide exchange factor 28)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF28 (Rho guanine nucleotide exchange factor 28)
Canis lupus familiaris (dog) : ARHGEF28 (Rho guanine nucleotide exchange factor 28)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef28 (Rho guanine nucleotide exchange factor 28)
Sus scrofa (pig) : ARHGEF28 (Rho guanine nucleotide exchange factor 28)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0225,738,514 - 26,011,429 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0244,892,452 - 45,152,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4228,492,591 - 28,767,567 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1228,408,913 - 28,695,327 (-)NCBI
Celera225,305,647 - 25,567,110 (-)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef28
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307061
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.