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Gene: Gabrb1 (gamma-aminobutyric acid type A receptor beta 1 subunit) Rattus norvegicus
Symbol: Gabrb1
Name: gamma-aminobutyric acid type A receptor beta 1 subunit
Description: Exhibits GABA receptor binding activity; GABA-A receptor activity; and ion channel activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Involved in several processes, including cellular response to histamine; central nervous system neuron development; and response to progesterone. Localizes to several cellular components, including the GABA-A receptor complex; GABA-ergic synapse; and nuclear envelope. Biomarker of hepatic encephalopathy. Human ortholog(s) of this gene implicated in autistic disorder and early infantile epileptic encephalopathy 45. Orthologous to human GABRB1 (gamma-aminobutyric acid type A receptor beta1 subunit); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
Also known as: GABA(A) receptor subunit beta-1; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1; Gamma-aminobutyric acid receptor beta 1; gamma-aminobutyric acid receptor subunit beta-1; gamma-aminobutyric acid receptor, subunit beta 1; GARB1
Allele / Splice: Gabrb1Tn(pb-Bhr2)1Wmukf  
Is Marker For: Strains:   SD   WKY-Tg(Gabrb1Tn(pb-Bhr2)1Wmukf)  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01438,631,192 - 39,112,598 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01438,453,142 - 38,924,073 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41438,530,259 - 39,005,615 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11438,532,649 - 39,008,000 (-)NCBI
Celera1435,310,585 - 35,771,142 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gabrb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2649
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.