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Gene: Unc5b (unc-5 netrin receptor B) Rattus norvegicus
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Symbol: Unc5b
Name: unc-5 netrin receptor B
Description: Exhibits netrin receptor activity. Involved in axon guidance and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand. Localizes to the membrane raft. Orthologous to human UNC5B (unc-5 netrin receptor B); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: netrin receptor UNC5B; transmembrane receptor Unc5H2; unc-5 homolog 2; unc-5 homolog B; unc-5 homolog B (C. elegans); Unc5h2
Orthologs:
Homo sapiens (human) : UNC5B (unc-5 netrin receptor B)  HGNC  Alliance
Mus musculus (house mouse) : Unc5b (unc-5 netrin receptor B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Unc5b (unc-5 netrin receptor B)
Pan paniscus (bonobo/pygmy chimpanzee) : UNC5B (unc-5 netrin receptor B)
Canis lupus familiaris (dog) : UNC5B (unc-5 netrin receptor B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Unc5b (unc-5 netrin receptor B)
Sus scrofa (pig) : UNC5B (unc-5 netrin receptor B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02030,339,680 - 30,406,593 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02032,148,315 - 32,215,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,095,243 - 28,162,204 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12028,109,042 - 28,176,004 (-)NCBI
Celera2030,138,282 - 30,201,182 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Unc5b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621756
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.