Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Spryd7 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SPRYD7 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Spryd7 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SPRYD7 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Estradiol results in increased expression of SPRYD7 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Spryd7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SPRYD7 mRNA | CTD | PMID:24680724 | 2-hydroxypropanoic acid | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SPRYD7 mRNA | CTD | PMID:30851411 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SPRYD7 mRNA | CTD | PMID:30047161 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SPRYD7 mRNA | CTD | PMID:31881176 | all-trans-retinoic acid | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SPRYD7 mRNA | CTD | PMID:33167477 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SPRYD7 mRNA | CTD | PMID:30047161 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of SPRYD7 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SPRYD7 mRNA | CTD | PMID:33212167 | arsenous acid | multiple interactions | ISO | SPRYD7 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to SPRYD7 protein] | CTD | PMID:26598702 | benzo[a]pyrene | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SPRYD7 mRNA | CTD | PMID:22316170 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SPRYD7 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SPRYD7 mRNA | CTD | PMID:36232920 | carbon nanotube | increases expression | ISO | Spryd7 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of SPRYD7 mRNA | CTD | PMID:25554681 | chlorpyrifos | decreases expression | ISO | Spryd7 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SPRYD7 mRNA | CTD | PMID:37019170 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of SPRYD7 mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SPRYD7 mRNA | CTD | PMID:19549813 | diarsenic trioxide | multiple interactions | ISO | SPRYD7 (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to SPRYD7 protein] | CTD | PMID:26598702 | diethylstilbestrol | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of SPRYD7 mRNA | CTD | PMID:36621641 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of SPRYD7 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | SPRYD7 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPRYD7 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SPRYD7 mRNA | CTD | PMID:29803840 | entinostat | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | entinostat results in increased expression of SPRYD7 mRNA | CTD | PMID:27188386 | epoxiconazole | increases expression | ISO | Spryd7 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of SPRYD7 mRNA | CTD | PMID:35436446 | ethanol | increases expression | ISO | Spryd7 (Mus musculus) | 6480464 | Ethanol results in increased expression of SPRYD7 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of SPRYD7 mRNA | CTD | PMID:23649840 | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of SPRYD7 mRNA | CTD | PMID:23962444 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SPRYD7 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Spryd7 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SPRYD7 mRNA | CTD | PMID:22206623 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SPRYD7 mRNA | CTD | PMID:33387578 | inulin | multiple interactions | ISO | Spryd7 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SPRYD7 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SPRYD7 protein | CTD | PMID:32959892 | lead(0) | affects expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Lead affects the expression of SPRYD7 mRNA | CTD | PMID:28903495 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SPRYD7 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of SPRYD7 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of SPRYD7 mRNA | CTD | PMID:28001369 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of SPRYD7 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of SPRYD7 mRNA | CTD | PMID:24136188 | paracetamol | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SPRYD7 mRNA | CTD | PMID:29067470 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SPRYD7 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Spryd7 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SPRYD7 mRNA more ... | CTD | PMID:36331819 | propiconazole | increases expression | EXP | | 6480464 | propiconazole results in increased expression of SPRYD7 mRNA | CTD | PMID:30047161 | rac-lactic acid | decreases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SPRYD7 mRNA | CTD | PMID:30851411 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SPRYD7 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | SPRYD7 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPRYD7 mRNA | CTD | PMID:27188386 | sodium arsenite | affects expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of SPRYD7 mRNA | CTD | PMID:29319823 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SPRYD7 mRNA | CTD | PMID:30047161 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SPRYD7 mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Spryd7 (Mus musculus) | 6480464 | triptonide results in increased expression of SPRYD7 mRNA | CTD | PMID:33045310 | troglitazone | increases expression | ISO | Spryd7 (Mus musculus) | 6480464 | troglitazone results in increased expression of SPRYD7 mRNA | CTD | PMID:28973697 | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of SPRYD7 mRNA | CTD | PMID:24136188 | valproic acid | affects expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SPRYD7 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | SPRYD7 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SPRYD7 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | SPRYD7 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPRYD7 mRNA | CTD | PMID:27188386 | |