Bmp1 (bone morphogenetic protein 1) - Rat Genome Database

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Gene: Bmp1 (bone morphogenetic protein 1) Rattus norvegicus
Analyze
Symbol: Bmp1
Name: bone morphogenetic protein 1
RGD ID: 620739
Description: Predicted to enable identical protein binding activity and metalloendopeptidase activity. Predicted to be involved in dorsal/ventral pattern formation and protein processing. Predicted to act upstream of or within positive regulation of cartilage development. Located in extracellular space and vesicle. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 13. Orthologous to human BMP1 (bone morphogenetic protein 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bone morphogenetic protein 1 (procollagen C-proteinase); procollagen C-proteinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,961,310 - 52,005,597 (-)NCBIGRCr8
mRatBN7.21545,551,603 - 45,595,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,669,483 - 49,713,645 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,780,998 - 50,825,151 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,640,279 - 47,684,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,166,401 - 52,210,786 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,889,918 - 55,934,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,878,144 - 50,922,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,910,779 - 50,923,437 (-)NCBI
Celera1545,230,611 - 45,274,179 (-)NCBICelera
Cytogenetic Map15p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aluminium oxide  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
astemizole  (EXP)
bacitracin  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
calciol  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroprene  (EXP)
chromium(6+)  (ISO)
cisplatin  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corn oil  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
fipronil  (EXP)
flutamide  (EXP)
gentamycin  (EXP)
glycerol 2-phosphate  (EXP)
graphene oxide  (ISO)
L-ascorbic acid  (EXP)
methotrexate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
nitric oxide  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenytoin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
simvastatin  (EXP)
Soman  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
extracellular space  (IBA,IDA)
vesicle  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Matrix vesicles are carriers of bone morphogenetic proteins (BMPs), vascular endothelial growth factor (VEGF), and noncollagenous matrix proteins. Nahar NN, etal., J Bone Miner Metab. 2008;26(5):514-9. Epub 2008 Aug 30.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tissue remodeling in the acute otitis media mouse model. Sautter NB, etal., Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1368-71. doi: 10.1016/j.ijporl.2011.07.026. Epub 2011 Sep 1.
Additional References at PubMed
PMID:3201241   PMID:12393877   PMID:16824737   PMID:17071617   PMID:19079247   PMID:19429706   PMID:21415150   PMID:24006456   PMID:28684382  


Genomics

Comparative Map Data
Bmp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81551,961,310 - 52,005,597 (-)NCBIGRCr8
mRatBN7.21545,551,603 - 45,595,862 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,669,483 - 49,713,645 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,780,998 - 50,825,151 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,640,279 - 47,684,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,166,401 - 52,210,786 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,889,918 - 55,934,263 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,878,144 - 50,922,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,910,779 - 50,923,437 (-)NCBI
Celera1545,230,611 - 45,274,179 (-)NCBICelera
Cytogenetic Map15p11NCBI
BMP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,165,372 - 22,212,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,165,140 - 22,212,326 (+)EnsemblGRCh38hg38GRCh38
GRCh37822,022,885 - 22,069,839 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,078,835 - 22,125,782 (+)NCBINCBI36Build 36hg18NCBI36
Celera820,984,783 - 21,032,542 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,564,967 - 20,612,031 (+)NCBIHuRef
CHM1_1822,224,312 - 22,271,500 (+)NCBICHM1_1
T2T-CHM13v2.0822,439,316 - 22,486,280 (+)NCBIT2T-CHM13v2.0
Bmp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,711,998 - 70,758,280 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,711,998 - 70,757,674 (-)EnsemblGRCm39 Ensembl
GRCm381470,474,555 - 70,520,716 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,474,558 - 70,520,234 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,874,362 - 70,920,067 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,209,638 - 69,255,268 (-)NCBIMGSCv36mm8
Celera1468,015,981 - 68,061,716 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Bmp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,660,588 - 45,693,724 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,660,591 - 45,693,724 (+)NCBIChiLan1.0ChiLan1.0
BMP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,666,831 - 40,714,042 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,392,228 - 16,439,248 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,410,139 - 21,457,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,349,836 - 18,396,796 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,349,836 - 18,396,796 (+)Ensemblpanpan1.1panPan2
BMP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,043,594 - 35,087,282 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,020,751 - 35,087,545 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,633,298 - 35,676,927 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,255,039 - 35,298,679 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,255,044 - 35,298,662 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,200,533 - 35,244,157 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,055,062 - 35,098,676 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,210,570 - 35,254,197 (-)NCBIUU_Cfam_GSD_1.0
Bmp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,546,649 - 12,579,706 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,990,836 - 6,023,878 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,990,822 - 6,023,864 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,443,912 - 6,489,063 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,443,773 - 6,489,066 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,881,220 - 6,923,093 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,234,242 - 20,281,768 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,234,184 - 20,283,467 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605221,954,309 - 22,001,797 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,744,821 - 17,788,510 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,745,344 - 17,788,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bmp1
91 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:122
Interacting mature miRNAs:141
Transcripts:ENSRNOT00000046054
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
7411725Strs7Sensitivity to stroke QTL 73.8cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)154028990149308583Rat
2306968Anxrr23Anxiety related response QTL 234.83reflex trait (VT:0001961)amplitude of the acoustic startle response (CMO:0001520)154063126846187442Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat

Markers in Region
BI278614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,551,817 - 45,551,986 (+)MAPPERmRatBN7.2
Rnor_6.01552,166,616 - 52,166,784NCBIRnor6.0
Rnor_5.01555,890,133 - 55,890,301UniSTSRnor5.0
RGSC_v3.41550,878,359 - 50,878,527UniSTSRGSC3.4
Celera1545,230,826 - 45,230,994UniSTS
Cytogenetic Map15p11UniSTS
RH94751  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,596,780 - 45,596,906 (+)MAPPERmRatBN7.2
Rnor_6.01552,211,751 - 52,211,876NCBIRnor6.0
Rnor_5.01555,935,268 - 55,935,393UniSTSRnor5.0
RGSC_v3.41550,923,318 - 50,923,443UniSTSRGSC3.4
Celera1545,275,184 - 45,275,309UniSTS
Cytogenetic Map15p11UniSTS
RH143871  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,556,132 - 45,556,291 (+)MAPPERmRatBN7.2
Rnor_6.01552,170,931 - 52,171,089NCBIRnor6.0
Rnor_5.01555,894,448 - 55,894,606UniSTSRnor5.0
RGSC_v3.41550,882,674 - 50,882,832UniSTSRGSC3.4
Celera1545,235,136 - 45,235,294UniSTS
Cytogenetic Map15p11UniSTS
RH136856  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21545,596,682 - 45,596,873 (+)MAPPERmRatBN7.2
Rnor_6.01552,211,653 - 52,211,843NCBIRnor6.0
Rnor_5.01555,935,170 - 55,935,360UniSTSRnor5.0
RGSC_v3.41550,923,220 - 50,923,410UniSTSRGSC3.4
Celera1545,275,086 - 45,275,276UniSTS
Cytogenetic Map15p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 54 41 16 41 4 5 70 24 41 11 4
Low 6 3 3 4 6 4 11 4
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000046054   ⟹   ENSRNOP00000040287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1545,551,603 - 45,595,776 (-)Ensembl
Rnor_6.0 Ensembl1552,166,401 - 52,210,746 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099340   ⟹   ENSRNOP00000083692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1545,583,813 - 45,595,776 (-)Ensembl
RefSeq Acc Id: NM_031323   ⟹   NP_112613
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,961,310 - 52,005,485 (-)NCBI
mRatBN7.21545,551,603 - 45,595,776 (-)NCBI
Rnor_6.01552,166,401 - 52,210,746 (-)NCBI
Rnor_5.01555,889,918 - 55,934,263 (-)NCBI
RGSC_v3.41550,878,144 - 50,922,313 (-)RGD
Celera1545,230,611 - 45,274,179 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252285   ⟹   XP_006252347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,961,312 - 51,994,213 (-)NCBI
mRatBN7.21545,551,605 - 45,584,510 (-)NCBI
Rnor_6.01552,166,403 - 52,199,169 (-)NCBI
Rnor_5.01555,889,918 - 55,934,263 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093689   ⟹   XP_038949617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,964,467 - 52,005,596 (-)NCBI
mRatBN7.21545,554,765 - 45,595,861 (-)NCBI
RefSeq Acc Id: XM_039093690   ⟹   XP_038949618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,961,312 - 51,994,213 (-)NCBI
mRatBN7.21545,551,605 - 45,584,510 (-)NCBI
RefSeq Acc Id: XM_063274694   ⟹   XP_063130764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,972,855 - 52,005,597 (-)NCBI
RefSeq Acc Id: XM_063274695   ⟹   XP_063130765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81551,974,490 - 52,005,596 (-)NCBI
RefSeq Acc Id: NP_112613   ⟸   NM_031323
- Peptide Label: precursor
- UniProtKB: F1M798 (UniProtKB/TrEMBL),   A6HTK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252347   ⟸   XM_006252285
- Peptide Label: isoform X2
- UniProtKB: A6HTK7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000040287   ⟸   ENSRNOT00000046054
RefSeq Acc Id: XP_038949618   ⟸   XM_039093690
- Peptide Label: isoform X3
- UniProtKB: A6HTK7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949617   ⟸   XM_039093689
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000083692   ⟸   ENSRNOT00000099340
RefSeq Acc Id: XP_063130764   ⟸   XM_063274694
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130765   ⟸   XM_063274695
- Peptide Label: isoform X5
Protein Domains
CUB   EGF-like   Peptidase M12A

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M798-F1-model_v2 AlphaFold F1M798 1-990 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699810
Promoter ID:EPDNEW_R10333
Type:initiation region
Name:Bmp1_1
Description:bone morphogenetic protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01552,210,683 - 52,210,743EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620739 AgrOrtholog
BioCyc Gene G2FUF-13214 BioCyc
Ensembl Genes ENSRNOG00000010890 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046054 ENTREZGENE
  ENSRNOT00000046054.5 UniProtKB/TrEMBL
  ENSRNOT00000099340.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.290 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro BMP_1/tolloid-like UniProtKB/TrEMBL
  CUB_dom UniProtKB/TrEMBL
  EG-like_dom UniProtKB/TrEMBL
  EGF-like_Ca-bd UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  Peptidase_M12A UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  sperma_CUB_dom UniProtKB/TrEMBL
  ZnMP_TLD/BMP1 UniProtKB/TrEMBL
KEGG Report rno:83470 UniProtKB/TrEMBL
NCBI Gene 83470 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 1 UniProtKB/TrEMBL
  DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING UniProtKB/TrEMBL
  METALLOENDOPEPTIDASE UniProtKB/TrEMBL
  OVOCHYMASE-RELATED UniProtKB/TrEMBL
Pfam Astacin UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/TrEMBL
PharmGKB BMP1 RGD
PhenoGen Bmp1 PhenoGen
PIRSF BMP_1/tolloid-like UniProtKB/TrEMBL
PRINTS ASTACIN UniProtKB/TrEMBL
PROSITE ASTACIN UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  CUB UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010890 RatGTEx
SMART CUB UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP CUB UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
  Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
UniProt A0A8I6A0H3_RAT UniProtKB/TrEMBL
  A6HTK6 ENTREZGENE, UniProtKB/TrEMBL
  A6HTK7 ENTREZGENE, UniProtKB/TrEMBL
  A6HTK8_RAT UniProtKB/TrEMBL
  F1M798 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Bmp1  bone morphogenetic protein 1    bone morphogenetic protein 1 (procollagen C-proetinase)  Name updated 1299863 APPROVED
2002-08-07 Bmp1  bone morphogenetic protein 1 (procollagen C-proetinase)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_product member of the TGF-beta superfamily 634636