Gene: Npc1 (NPC intracellular cholesterol transporter 1) Rattus norvegicus
Symbol: Npc1
Name: NPC intracellular cholesterol transporter 1
Description: ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN negative regulation of cell death; response to cadmium ion; adult walking behavior (ortholog); ASSOCIATED WITH Ataxia (ortholog); atherosclerosis (ortholog); brucellosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); endosome (ortholog); extracellular region (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cdig2; Niemann-Pick disease, type C1; SLC66A1; solute carrier family 66 member 1
Homo sapiens (human) : NPC1 (NPC intracellular cholesterol transporter 1)  HGNC  Alliance
Mus musculus (house mouse) : Npc1 (NPC intracellular cholesterol transporter 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npc1 (NPC intracellular cholesterol transporter 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NPC1 (NPC intracellular cholesterol transporter 1)
Canis lupus familiaris (dog) : NPC1 (NPC intracellular cholesterol transporter 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npc1 (NPC intracellular cholesterol transporter 1)
Sus scrofa (pig) : NPC1 (NPC intracellular cholesterol transporter 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0183,616,878 - 3,662,656 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,626,015 - 3,671,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,725,415 - 3,777,707 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1183,725,710 - 3,726,684 (-)NCBI
Celera183,239,322 - 3,285,547 (-)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Npc1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628693
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE