Loxl2 (lysyl oxidase-like 2) - Rat Genome Database

Name: Loxl2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Loxl2 (lysyl oxidase-like 2) Rattus norvegicus

Analyze

Symbol:

Loxl2

Name:

lysyl oxidase-like 2

RGD ID:

1308435

Description:

Predicted to enable metal ion binding activity; oligosaccharide binding activity; and protein-lysine 6-oxidase activity. Predicted to be involved in several processes, including collagen fibril organization; positive regulation of cell differentiation; and response to copper ion. Located in basement membrane. Orthologous to human LOXL2 (lysyl oxidase like 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC290350; lysyl oxidase homolog 2; lysyl oxidase-like protein 2; MGC189171

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LOXL2 (lysyl oxidase like 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Loxl2 (lysyl oxidase-like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Loxl2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Loxl2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOXL2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Loxl2 (lysyl oxidase like 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KDR (kinase insert domain receptor)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	LOXL2 (lysyl oxidase like 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Loxl2 (lysyl oxidase-like 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	loxl2b (lysyl oxidase-like 2b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	loxl2a (lysyl oxidase-like 2a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Loxl1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Loxl2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	loxl2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,091,547 - 51,182,843 (+)	NCBI		GRCr8
mRatBN7.2	15	44,683,449 - 44,773,067 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	44,683,880 - 44,773,067 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	48,801,847 - 48,888,730 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	49,913,342 - 50,000,223 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	46,772,671 - 46,859,556 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	51,276,022 - 51,365,238 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	51,303,909 - 51,365,234 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,005,461 - 55,092,980 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	49,982,103 - 50,068,902 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,024,097 - 50,084,571 (+)	NCBI
Celera	15	44,366,507 - 44,453,187 (+)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

Breast Neoplasms (ISO)

Conotruncal Cardiac Defects (ISO)

esophagus squamous cell carcinoma (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

hepatitis B (ISO)

hepatitis C (ISO)

Neoplasm Invasiveness (ISO)

Neoplastic Cell Transformation (ISO)

primary biliary cholangitis (ISO)

Wilson disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzo[e]pyrene (ISO)

bexarotene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloroprene (EXP)

choline (ISO)

chromium(6+) (ISO)

cisplatin (EXP,ISO)

cobalt atom (ISO)

cobalt dichloride (EXP,ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-penicillamine (ISO)

dexamethasone (ISO)

diazinon (ISO)

dibutyl phthalate (ISO)

disodium selenite (ISO)

diuron (EXP)

dopamine (EXP)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

fenoldopam (EXP)

fenvalerate (EXP)

fipronil (EXP)

folic acid (ISO)

graphene oxide (ISO)

isotretinoin (ISO)

ivermectin (ISO)

L-ascorbic acid (ISO)

L-methionine (ISO)

methapyrilene (ISO)

methimazole (EXP)

methotrexate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-nitrosodimethylamine (EXP)

nickel dichloride (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

pentane-2,3-dione (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

PhIP (EXP)

progesterone (ISO)

rotenone (EXP,ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone enanthate (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

topotecan (ISO)

tributylstannane (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

Tungsten carbide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

collagen fibril organization (IBA,IEA,ISO,ISS)

endothelial cell migration (IEA,ISO,ISS)

endothelial cell proliferation (IEA,ISO,ISS)

epithelial to mesenchymal transition (IEA,ISO,ISS)

heterochromatin organization (IEA,ISO,ISS)

negative regulation of DNA-templated transcription (ISO,ISS)

negative regulation of stem cell population maintenance (IEA,ISO,ISS)

negative regulation of transcription by RNA polymerase II (IEA,ISO,ISS)

positive regulation of chondrocyte differentiation (IEA,ISO,ISS)

positive regulation of epithelial to mesenchymal transition (IEA,ISO,ISS)

protein modification process (IEA,ISO,ISS)

response to copper ion (IEA,ISO,ISS)

response to hypoxia (IEA,ISO,ISS)

sprouting angiogenesis (IEA,ISO,ISS)

Cellular Component

basement membrane (IDA,IEA)

chromatin (IEA,ISO,ISS)

chromosome (IEA)

collagen-containing extracellular matrix (IBA)

endoplasmic reticulum (IEA,ISO,ISS)

extracellular space (IBA,IEA,ISO,ISS)

membrane (IEA)

nucleoplasm (IEA,ISO)

nucleus (IEA,ISO,ISS)

Molecular Function

calcium ion binding (IEA,ISO,ISS)

copper ion binding (IEA,ISO,ISS)

oligosaccharide binding (IEA,ISO,ISS)

protein binding (ISO)

protein-lysine 6-oxidase activity (IBA,IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane.	Bignon M, etal., Blood. 2011 Oct 6;118(14):3979-89. doi: 10.1182/blood-2010-10-313296. Epub 2011 Aug 11.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:16096638	PMID:21071451	PMID:22204712	PMID:23319596	PMID:23979707	PMID:24006456	PMID:24239292	PMID:24414204	PMID:25959397	PMID:27735137	PMID:28332555
PMID:29581294	PMID:29966587	PMID:34426599

Genomics

Comparative Map Data

Loxl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	51,091,547 - 51,182,843 (+)	NCBI		GRCr8
mRatBN7.2	15	44,683,449 - 44,773,067 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	44,683,880 - 44,773,067 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	48,801,847 - 48,888,730 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	49,913,342 - 50,000,223 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	46,772,671 - 46,859,556 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	51,276,022 - 51,365,238 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	51,303,909 - 51,365,234 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	55,005,461 - 55,092,980 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	49,982,103 - 50,068,902 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	50,024,097 - 50,084,571 (+)	NCBI
Celera	15	44,366,507 - 44,453,187 (+)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

LOXL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	23,296,897 - 23,404,120 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	23,296,897 - 23,425,328 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	23,154,410 - 23,261,633 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	23,210,355 - 23,317,667 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	23,210,640 - 23,317,575	NCBI
Celera	8	22,116,981 - 22,224,289 (-)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	21,700,441 - 21,807,111 (-)	NCBI		HuRef
CHM1_1	8	23,356,541 - 23,463,832 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	23,571,770 - 23,679,001 (-)	NCBI		T2T-CHM13v2.0

Loxl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	69,846,085 - 69,933,283 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	69,846,517 - 69,933,283 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	69,608,692 - 69,695,834 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	69,609,068 - 69,695,834 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	70,009,283 - 70,095,641 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	68,344,556 - 68,428,775 (+)	NCBI		MGSCv36	mm8
Celera	14	67,164,771 - 67,231,456 (+)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI
cM Map	14	36.06	NCBI

Loxl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	46,504,440 - 46,584,016 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	46,503,226 - 46,583,807 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOXL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	41,802,508 - 41,909,114 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	17,529,707 - 17,636,058 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	22,547,303 - 22,653,676 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	19,483,331 - 19,589,522 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	19,483,335 - 19,589,522 (-)	Ensembl	panpan1.1		panPan2

LOXL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	34,095,858 - 34,186,775 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	34,126,335 - 34,185,969 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	34,684,511 - 34,775,173 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	34,303,470 - 34,394,384 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	34,303,481 - 34,394,388 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	34,249,922 - 34,341,273 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	34,104,318 - 34,195,732 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	34,259,681 - 34,351,266 (+)	NCBI		UU_Cfam_GSD_1.0

Loxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	11,704,822 - 11,789,837 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	6,781,321 - 6,865,768 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	6,781,563 - 6,865,662 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOXL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	7,435,867 - 7,540,704 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	7,435,861 - 7,540,699 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOXL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	21,416,821 - 21,516,923 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	21,416,787 - 21,516,854 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	20,707,763 - 20,805,731 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Loxl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	18,568,607 - 18,621,785 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	18,567,367 - 18,644,528 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Loxl2
199 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	82
Count of miRNA genes:	68
Interacting mature miRNAs:	71
Transcripts:	ENSRNOT00000058663
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
7411725	Strs7	Sensitivity to stroke QTL 7	3.8		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	15	40289901	49308583	Rat
2306968	Anxrr23	Anxiety related response QTL 23	4.83		reflex trait (VT:0001961)	amplitude of the acoustic startle response (CMO:0001520)	15	40631268	46187442	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat

Markers in Region

D15Mgh11

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	44,759,391 - 44,759,533 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	51,353,605 - 51,353,746	NCBI	Rnor6.0
Rnor_5.0	15	55,081,347 - 55,081,488	UniSTS	Rnor5.0
RGSC_v3.4	15	50,057,446 - 50,057,588	RGD	RGSC3.4
RGSC_v3.4	15	50,057,447 - 50,057,588	UniSTS	RGSC3.4
RGSC_v3.1	15	50,073,226 - 50,073,368	RGD
Celera	15	44,441,732 - 44,441,873	UniSTS
FHH x ACI Map	15	46.36	RGD
FHH x ACI Map	15	46.36	UniSTS
Cytogenetic Map	15	p11	UniSTS

D15Arb7

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	44,759,312 - 44,759,531 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	51,353,526 - 51,353,744	NCBI	Rnor6.0
Rnor_5.0	15	55,081,268 - 55,081,486	UniSTS	Rnor5.0
RGSC_v3.4	15	50,057,367 - 50,057,586	RGD	RGSC3.4
RGSC_v3.4	15	50,057,368 - 50,057,586	UniSTS	RGSC3.4
RGSC_v3.1	15	50,073,147 - 50,073,366	RGD
Celera	15	44,441,653 - 44,441,871	UniSTS
Cytogenetic Map	15	p11	UniSTS

D15Wox4

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	44,759,329 - 44,759,531 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	51,353,543 - 51,353,744	NCBI	Rnor6.0
Rnor_5.0	15	55,081,285 - 55,081,486	UniSTS	Rnor5.0
RGSC_v3.4	15	50,057,385 - 50,057,586	UniSTS	RGSC3.4
Celera	15	44,441,670 - 44,441,871	UniSTS
Cytogenetic Map	15	p11	UniSTS

RH124140

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	44,766,673 - 44,767,926 (+)	MAPPER	mRatBN7.2
mRatBN7.2	4	115,555,823 - 115,556,054 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	113,882,579 - 113,882,809	NCBI	Rnor6.0
Rnor_6.0	15	51,361,065 - 51,362,317	NCBI	Rnor6.0
Rnor_5.0	15	55,088,807 - 55,090,059	UniSTS	Rnor5.0
Rnor_5.0	4	178,567,679 - 178,567,909	UniSTS	Rnor5.0
RGSC_v3.4	4	117,261,114 - 117,261,344	UniSTS	RGSC3.4
RGSC_v3.4	15	50,064,728 - 50,065,980	UniSTS	RGSC3.4
Celera	15	44,449,013 - 44,450,265	UniSTS
Celera	4	104,550,500 - 104,550,730	UniSTS
Cytogenetic Map	4	q34	UniSTS
Cytogenetic Map	15	p11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	35	24	15	10	15	5	6	14	28	33	11	5
Low	1	8	33	26	9	26	3	5	60	7	8		3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093154	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000058663 ⟹ ENSRNOP00000055457

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	44,719,957 - 44,773,067 (+)	Ensembl
Rnor_6.0 Ensembl	15	51,304,059 - 51,365,124 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000085237 ⟹ ENSRNOP00000073118

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	44,683,880 - 44,773,064 (+)	Ensembl
Rnor_6.0 Ensembl	15	51,303,909 - 51,365,234 (+)	Ensembl

RefSeq Acc Id:

NM_001106047 ⟹ NP_001099517

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,738 - 51,180,624 (+)	NCBI
mRatBN7.2	15	44,683,944 - 44,770,848 (+)	NCBI
Rnor_6.0	15	51,276,022 - 51,365,238 (+)	NCBI
Rnor_5.0	15	55,005,461 - 55,092,980 (+)	NCBI
RGSC_v3.4	15	49,982,103 - 50,068,902 (+)	RGD
Celera	15	44,366,507 - 44,453,187 (+)	RGD

Sequence:

show sequence

CTGCATTTTCCCCTGGCTTCTCCGCGGGCGGGCCCTCGGCGATCGGCGTGGAGAGGGGCCACCG
CTGAGATCCCAGTCCCTGCCTGGCCACCACGGAGTCCAGCTACCAACACAGGACAAGGATGGAG
ATCCCTTTTGGCTCCTGCCTCTACAGCTGTTTGGCACTGCTTGTCTTGCTGCCCTCCCTGAGCC
TAGCACAATATGAGAGCTGGCCCTACCAGCTCCAATATCCCGAGTACTTCCAGCAGCCGCCTCC
CGAGCACCACCAGCATCAGGTGCCCTCCGACGTGGTGAAGATCCAGGTCCGCCTGGCGGGCCAG
AAGAGGAAACATAATGAAGGCCGTGTGGAGGTCTATTACGAAGGCCAGTGGGGCACTGTGTGCG
ATGATGATTTCTCTATCCATGCTGCCCATGTTGTCTGCCGGGAAGTGGGCTATGTGGAGGCCAA
GTCCTGGACTGCCAGCTCCTCCTACGGCCCAGGCGAAGGCCCCATCTGGTTGGACAACATCTAC
TGCACAGGCAAAGAGTCAACCCTGGCAGCTTGCTCCTCTAATGGCTGGGGTGTCACTGATTGCA
AGCACACTGAAGATGTTGGTGTGGTGTGCAGTGAAAAAAGAATTCCAGGCTTCAAATTTGACAA
TTCATTGATCAACCAAATAGAGAGCCTAAATATACAGGTGGAAGACATCCGGATTCGACCCATC
CTGTCTGCCTTCCGCCATCGCAAGCCTGTGACAGAGGGCTACGTGGAGGTAAAGGAGGGCAAGG
CCTGGAAGCAGATCTGTGACAAGCACTGGACAGCCAAGAATTCCCACGTGGTCTGTGGCATGTT
TGGCTTCCCAGCAGAGAAGACTTACAACCCCAAAGCCTACAAAACCTTTGCCTCAAGGAGGAAG
CTGCGCTACTGGAAGTTTTCTATGAACTGCACGGGAACTGAAGCACACATCTCCAGCTGTAAGC
TGGGCCCTCCCATGTTCCGGGACCCTGTGAAGAATGCCACCTGTGAGAACGGGCAGCCAGCTGT
GGTCAGTTGTGTGCCTAGCCAGATCTTCAGCCCTGATGGACCCTCAAGGTTCCGGAAAGCCTAT
AAGCCGGAGCAACCCTTGGTGCGACTGAGAGGTGGAGCCCAGGTCGGGGAGGGCCGCGTGGAGG
TGCTCAAGAATGGAGAATGGGGTACCGTCTGCGATGACAAGTGGGACCTGGTGTCTGCCAGCGT
GGTCTGCAGGGAGCTGGGCTTCGGCACAGCTAAAGAGGCTGTCACAGGCTCCAGGCTGGGGCAA
GGGATTGGGCCCATCCACCTCAACGAGGTCCAGTGCACAGGGACAGAGAAGTCCATCATAGACT
GCAAGCTCAACACAGAGTCGCAGGGCTGCAACCACGAGGAAGACGCCGGAGTGCGATGCAACAT
CCCCATCATGGGCTTCCAGAAAAAGGTGCGCCTGAATGGAGGCCGCAATCCCTATGAGGGTCGA
GTGGAGGTACTAACAGAGAGAAATGGGTCCCTCGTGTGGGGGAATGTATGTGGCCAGAACTGGG
GCATTGTGGAAGCCATGGTGGTCTGCCGGCAGCTAGGATTGGGCTTTGCCAGCAACGCCTTCCA
GGAAACCTGGTACTGGCATGGAAATATCTTCGCCAACAAAGTGATCATGAGTGGAGTGAAGTGC
TCAGGAACGGAGTTATCCCTGGCACACTGCCGCCATGACGAGGAGGTGGTCTGCCCCGAGGGTG
GGGTGCAGTATGGTGCTGGAGTCGCCTGCTCAGAAACTGCACCTGACCTGGTACTTAACGCCGA
GATTGTACAACAGACCGCCTATCTGGAGGACAGGCCCATGGCCTTGCTGCAGTGTGCCATGGAG
GAAAACTGCCTCTCAGCCTCCGCTGTGCACACCGATCCCACCAGAGGCCACCGTCGCCTTCTAC
GCTTCTCTTCCCAGATCCACAACAATGGCCAATCTGACTTCCGCCCCAAGAATGGCCGCCATGC
ATGGATTTGGCATGACTGCCACAGGCACTACCACAGCATGGAAGTATTCACTTACTATGACCTC
CTGAGCCTCAACGGCACCAAGGTGGCTGAGGGCCACAAGGCCAGCTTCTGCTTGGAGGACACTG
AGTGTGAGGGAGACATTCAGAAGAGTTACGAGTGTGCCAACTTCGGAGAACAAGGCATCACCAT
GGGCTGCTGGGACATGTATCGTCATGACATTGACTGCCAGTGGATAGACATCACCGATGTGCCC
CCTGGAGACTACCTGTTTCAGGTTGTCATTAACCCCAACTATGAGGTGCCAGAATCAGATTTCT
CTAACAACATCATGAAGTGCAGGAGCCGCTATGATGGCTACCGCATCTGGATGTACAATTGTCA
CGTAGGTGGAGCCTTCAGTGAGGAGACAGAACAGAAGTTCGAACACTTCAGTGGACTCCTAAAT
AATCAGCTCTCTGTGCAGTAAAGACGACTCTGGGCCAGGCATGATGGCTCATGCCTGTAATCCC
CGCACTCAGGCAGGAGGATTGCCACAAGATTTTCACTCTGGACACTAGACCAAGCTTCAGTCTC
AAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039093148 ⟹ XP_038949076

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,279 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,475 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093149 ⟹ XP_038949077

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,279 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,475 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093150 ⟹ XP_038949078

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,352 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,477 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093151 ⟹ XP_038949079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,654 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,839 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093152 ⟹ XP_038949080

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,653 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,838 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093153 ⟹ XP_038949081

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,251 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,449 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093154 ⟹ XP_038949082

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,352 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,479 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_039093155 ⟹ XP_038949083

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,091,547 - 51,182,843 (+)	NCBI
mRatBN7.2	15	44,683,481 - 44,773,067 (+)	NCBI

RefSeq Acc Id:

XM_063274138 ⟹ XP_063130208

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	51,093,564 - 51,182,843 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099517	(Get FASTA)	NCBI Sequence Viewer
	XP_038949076	(Get FASTA)	NCBI Sequence Viewer
	XP_038949077	(Get FASTA)	NCBI Sequence Viewer
	XP_038949078	(Get FASTA)	NCBI Sequence Viewer
	XP_038949079	(Get FASTA)	NCBI Sequence Viewer
	XP_038949080	(Get FASTA)	NCBI Sequence Viewer
	XP_038949081	(Get FASTA)	NCBI Sequence Viewer
	XP_038949082	(Get FASTA)	NCBI Sequence Viewer
	XP_038949083	(Get FASTA)	NCBI Sequence Viewer
	XP_063130208	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68900	(Get FASTA)	NCBI Sequence Viewer
	B5DF27	(Get FASTA)	NCBI Sequence Viewer
	EDM02189	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000055457.5
	ENSRNOP00000073118
	ENSRNOP00000073118.2

RefSeq Acc Id:	NP_001099517 ⟸ NM_001106047
- Peptide Label:	precursor
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot), A0A0G2K4P0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEIPFGSCLYSCLALLVLLPSLSLAQYESWPYQLQYPEYFQQPPPEHHQHQVPSDVVKIQVRLA GQKRKHNEGRVEVYYEGQWGTVCDDDFSIHAAHVVCREVGYVEAKSWTASSSYGPGEGPIWLDN IYCTGKESTLAACSSNGWGVTDCKHTEDVGVVCSEKRIPGFKFDNSLINQIESLNIQVEDIRIR PILSAFRHRKPVTEGYVEVKEGKAWKQICDKHWTAKNSHVVCGMFGFPAEKTYNPKAYKTFASR RKLRYWKFSMNCTGTEAHISSCKLGPPMFRDPVKNATCENGQPAVVSCVPSQIFSPDGPSRFRK AYKPEQPLVRLRGGAQVGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGTAKEAVTGSRL GQGIGPIHLNEVQCTGTEKSIIDCKLNTESQGCNHEEDAGVRCNIPIMGFQKKVRLNGGRNPYE GRVEVLTERNGSLVWGNVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGNIFANKVIMSGV KCSGTELSLAHCRHDEEVVCPEGGVQYGAGVACSETAPDLVLNAEIVQQTAYLEDRPMALLQCA MEENCLSASAVHTDPTRGHRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTYY DLLSLNGTKVAEGHKASFCLEDTECEGDIQKSYECANFGEQGITMGCWDMYRHDIDCQWIDITD VPPGDYLFQVVINPNYEVPESDFSNNIMKCRSRYDGYRIWMYNCHVGGAFSEETEQKFEHFSGL LNNQLSVQ hide sequence

RefSeq Acc Id:

ENSRNOP00000073118 ⟸ ENSRNOT00000085237

RefSeq Acc Id:

ENSRNOP00000055457 ⟸ ENSRNOT00000058663

RefSeq Acc Id:	XP_038949081 ⟸ XM_039093153
- Peptide Label:	isoform X4
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038949076 ⟸ XM_039093148
- Peptide Label:	isoform X1
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038949077 ⟸ XM_039093149
- Peptide Label:	isoform X2
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038949078 ⟸ XM_039093150
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038949082 ⟸ XM_039093154
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038949083 ⟸ XM_039093155
- Peptide Label:	isoform X6
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038949080 ⟸ XM_039093152
- Peptide Label:	isoform X4
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038949079 ⟸ XM_039093151
- Peptide Label:	isoform X4
- UniProtKB:	F1LPM2 (UniProtKB/Swiss-Prot), B5DF27 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063130208 ⟸ XM_063274138
- Peptide Label:	isoform X7

Protein Domains

SRCR

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DF27-F1-model_v2	AlphaFold	B5DF27	1-776	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308435	AgrOrtholog
BioCyc Gene	G2FUF-13255	BioCyc
Ensembl Genes	ENSRNOG00000016758	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000058663.5	UniProtKB/TrEMBL
	ENSRNOT00000085237	ENTREZGENE
	ENSRNOT00000085237.2	UniProtKB/TrEMBL
Gene3D-CATH	3.10.250.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Lysyl_oxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Lysyl_oxidase_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRCR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRCR-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRCR-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:290350	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	290350	ENTREZGENE
PANTHER	LYSYL OXIDASE HOMOLOG 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LYSYL OXIDASE-LIKE-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Lysyl_oxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRCR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Loxl2	PhenoGen
PRINTS	LYSYLOXIDASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SPERACTRCPTR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	LYSYL_OXIDASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRCR_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRCR_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016758	RatGTEx
SMART	SM00202	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56487	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2K4P0	ENTREZGENE, UniProtKB/TrEMBL
	B5DF27	ENTREZGENE
	F1LPM2	ENTREZGENE
	J3QTE1_RAT	UniProtKB/TrEMBL
	LOXL2_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	F1LPM2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Loxl2	lysyl oxidase-like 2	Loxl2_predicted	lysyl oxidase-like 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Loxl2_predicted	lysyl oxidase-like 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD