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Gene: Dmpk (DM1 protein kinase) Rattus norvegicus
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Symbol: Dmpk
Name: DM1 protein kinase
Description: Predicted to have ATP binding activity; myosin phosphatase regulator activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including muscle cell apoptotic process; regulation of skeletal muscle contraction; and regulation of synapse structural plasticity. Localizes to the membrane. Human ortholog(s) of this gene implicated in myotonic dystrophy type 1. Orthologous to human DMPK (DM1 protein kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5-triiodo-L-thyronine; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Dm15; dystrophia myotonica kinase, B15; dystrophia myotonica-protein kinase; LOC308405; myotonin-protein kinase
Orthologs:
Homo sapiens (human) : DMPK (DM1 protein kinase)  HGNC  Alliance
Mus musculus (house mouse) : Dmpk (dystrophia myotonica-protein kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dmpk (DM1 protein kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : DMPK (DM1 protein kinase)
Canis lupus familiaris (dog) : DMPK (DM1 protein kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dmpk (DM1 protein kinase)
Sus scrofa (pig) : DMPK (DM1 protein kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0179,988,096 - 79,999,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,257,000 - 81,267,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,449,324 - 78,450,578 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1178,518,239 - 78,529,227 (+)NCBI
Celera173,194,993 - 73,206,254 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dmpk
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309825
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.