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Gene: Ubxn8 (UBX domain protein 8) Rattus norvegicus

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Symbol:

Ubxn8

Name:

UBX domain protein 8

RGD ID:

1306023

Description:

Predicted to enable ubiquitin binding activity. Predicted to be involved in ERAD pathway. Predicted to be located in endoplasmic reticulum membrane; nucleolus; and nucleoplasm. Orthologous to human UBXN8 (UBX domain protein 8); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC290802; RGD1306023; similar to reproduction 8; UBX domain containing 6; UBX domain-containing protein 8; Ubxd6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UBXN8 (UBX domain protein 8)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther
Mus musculus (house mouse):	Ubxn8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ubxn8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UBXN8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UBXN8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ubxn8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UBXN8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UBXN8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ubxn8 (UBX domain protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	UBXN8 (UBX domain protein 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ubxn8 (UBX domain protein 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ubxn8 (UBX domain protein 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ubxn8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	65,239,149 - 65,260,743 (+)	NCBI		GRCr8
mRatBN7.2	16	58,536,086 - 58,557,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	58,536,086 - 58,557,684 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	63,873,647 - 63,895,266 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	67,287,312 - 67,308,931 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	62,507,878 - 62,529,497 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	62,251,243 - 62,272,838 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	62,251,243 - 62,272,838 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	61,911,951 - 61,933,546 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	62,308,482 - 62,330,075 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	62,309,492 - 62,328,941 (+)	NCBI
Celera	16	56,572,162 - 56,593,770 (+)	NCBI		Celera
Cytogenetic Map	16	q12.3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ubxn8	Rat	(+)-schisandrin B	multiple interactions	EXP		6480464	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBXN8 mRNA]	CTD	PMID:31150632
Ubxn8	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	RGD:1622160	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UBXN8 mRNA	CTD	PMID:36331819
Ubxn8	Rat	1,2-dimethylhydrazine	increases expression	ISO	RGD:1622160	6480464	1,2-Dimethylhydrazine results in increased expression of UBXN8 mRNA	CTD	PMID:22206623
Ubxn8	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of UBXN8 mRNA	CTD	PMID:33387578
Ubxn8	Rat	acrylamide	increases expression	ISO	RGD:1603319	6480464	Acrylamide results in increased expression of UBXN8 mRNA	CTD	PMID:32763439
Ubxn8	Rat	all-trans-retinoic acid	decreases expression	ISO	RGD:1603319	6480464	Tretinoin results in decreased expression of UBXN8 mRNA	CTD	PMID:23724009
Ubxn8	Rat	aristolochic acid A	decreases expression	ISO	RGD:1603319	6480464	aristolochic acid I results in decreased expression of UBXN8 mRNA	CTD	PMID:33212167
Ubxn8	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1603319	6480464	Benzo(a)pyrene results in increased expression of UBXN8 mRNA	CTD	PMID:26238291
Ubxn8	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1603319	6480464	Benzo(a)pyrene results in increased methylation of UBXN8 promoter	CTD	PMID:27901495
Ubxn8	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1622160	6480464	Diethylhexyl Phthalate results in decreased expression of UBXN8 mRNA	CTD	PMID:34319233
Ubxn8	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of UBXN8 mRNA	CTD	PMID:25181051\|PMID:34947998
Ubxn8	Rat	bisphenol A	decreases expression	ISO	RGD:1622160	6480464	bisphenol A results in decreased expression of UBXN8 mRNA	CTD	PMID:33221593
Ubxn8	Rat	cadmium dichloride	decreases methylation	EXP		6480464	Cadmium Chloride results in decreased methylation of UBXN8 promoter	CTD	PMID:22457795
Ubxn8	Rat	carbon nanotube	increases expression	ISO	RGD:1622160	6480464	Nanotubes, Carbon analog results in increased expression of UBXN8 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681
Ubxn8	Rat	chlordecone	decreases expression	ISO	RGD:1622160	6480464	Chlordecone results in decreased expression of UBXN8 mRNA	CTD	PMID:29980752
Ubxn8	Rat	clofibrate	multiple interactions	ISO	RGD:1622160	6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of UBXN8 mRNA; PPARA affects the reaction [[Clofibrate more ...	CTD	PMID:17585979
Ubxn8	Rat	cobalt dichloride	increases expression	EXP		6480464	cobaltous chloride results in increased expression of UBXN8 mRNA	CTD	PMID:24386269
Ubxn8	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1603319	6480464	di-n-butylphosphoric acid affects the expression of UBXN8 mRNA	CTD	PMID:37042841
Ubxn8	Rat	dicrotophos	decreases expression	ISO	RGD:1603319	6480464	dicrotophos results in decreased expression of UBXN8 mRNA	CTD	PMID:28302478
Ubxn8	Rat	endosulfan	increases expression	EXP		6480464	Endosulfan results in increased expression of UBXN8 mRNA	CTD	PMID:29391264
Ubxn8	Rat	epoxiconazole	decreases expression	ISO	RGD:1622160	6480464	epoxiconazole results in decreased expression of UBXN8 mRNA	CTD	PMID:35436446
Ubxn8	Rat	fenthion	increases expression	ISO	RGD:1622160	6480464	Fenthion results in increased expression of UBXN8 mRNA	CTD	PMID:34813904
Ubxn8	Rat	fipronil	increases expression	EXP		6480464	fipronil results in increased expression of UBXN8 mRNA	CTD	PMID:23962444
Ubxn8	Rat	flutamide	increases expression	EXP		6480464	Flutamide results in increased expression of UBXN8 mRNA	CTD	PMID:24136188
Ubxn8	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of UBXN8 mRNA	CTD	PMID:33387578
Ubxn8	Rat	glyphosate	decreases expression	EXP		6480464	Glyphosate results in decreased expression of UBXN8 mRNA	CTD	PMID:26302742
Ubxn8	Rat	GSK-J4	decreases expression	ISO	RGD:1603319	6480464	GSK-J4 results in decreased expression of UBXN8 mRNA	CTD	PMID:29301935
Ubxn8	Rat	hydrogen peroxide	affects expression	ISO	RGD:1603319	6480464	Hydrogen Peroxide affects the expression of UBXN8 mRNA	CTD	PMID:20044591
Ubxn8	Rat	nitrates	multiple interactions	ISO	RGD:1622160	6480464	[Particulate Matter results in increased abundance of Nitrates] which results in increased expression of UBXN8 more ...	CTD	PMID:35964746
Ubxn8	Rat	paracetamol	multiple interactions	ISO	RGD:1622160	6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of UBXN8 mRNA; PPARA affects the reaction [[Clofibrate more ...	CTD	PMID:17585979
Ubxn8	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of UBXN8 mRNA	CTD	PMID:33387578
Ubxn8	Rat	paracetamol	decreases expression	ISO	RGD:1603319	6480464	Acetaminophen results in decreased expression of UBXN8 mRNA	CTD	PMID:29067470
Ubxn8	Rat	paracetamol	affects expression	ISO	RGD:1622160	6480464	Acetaminophen affects the expression of UBXN8 mRNA	CTD	PMID:17562736
Ubxn8	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	RGD:1622160	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UBXN8 mRNA; [perfluorooctane sulfonic more ...	CTD	PMID:36331819
Ubxn8	Rat	phenobarbital	affects expression	ISO	RGD:1603319	6480464	Phenobarbital affects the expression of UBXN8 mRNA	CTD	PMID:19159669
Ubxn8	Rat	propiconazole	increases expression	ISO	RGD:1622160	6480464	propiconazole results in increased expression of UBXN8 mRNA	CTD	PMID:21278054
Ubxn8	Rat	silicon dioxide	decreases expression	ISO	RGD:1603319	6480464	Silicon Dioxide results in decreased expression of UBXN8 mRNA	CTD	PMID:25351596
Ubxn8	Rat	silver atom	decreases expression	ISO	RGD:1622160	6480464	Silver results in decreased expression of UBXN8 mRNA	CTD	PMID:27131904
Ubxn8	Rat	silver(0)	decreases expression	ISO	RGD:1622160	6480464	Silver results in decreased expression of UBXN8 mRNA	CTD	PMID:27131904
Ubxn8	Rat	tetrachloromethane	increases expression	EXP		6480464	Carbon Tetrachloride results in increased expression of UBXN8 mRNA	CTD	PMID:31150632
Ubxn8	Rat	tetrachloromethane	multiple interactions	EXP		6480464	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of UBXN8 mRNA]	CTD	PMID:31150632
Ubxn8	Rat	thapsigargin	increases expression	ISO	RGD:1603319	6480464	Thapsigargin results in increased expression of UBXN8 mRNA	CTD	PMID:29453283
Ubxn8	Rat	titanium dioxide	decreases methylation	ISO	RGD:1622160	6480464	titanium dioxide results in decreased methylation of UBXN8 promoter	CTD	PMID:35295148
Ubxn8	Rat	trichostatin A	decreases expression	ISO	RGD:1603319	6480464	trichostatin A results in decreased expression of UBXN8 mRNA	CTD	PMID:28542535
Ubxn8	Rat	triphenyl phosphate	affects expression	ISO	RGD:1603319	6480464	triphenyl phosphate affects the expression of UBXN8 mRNA	CTD	PMID:37042841
Ubxn8	Rat	Triptolide	increases expression	EXP		6480464	triptolide results in increased expression of UBXN8 protein	CTD	PMID:32519852
Ubxn8	Rat	urethane	decreases expression	ISO	RGD:1603319	6480464	Urethane results in decreased expression of UBXN8 mRNA	CTD	PMID:28818685
Ubxn8	Rat	valproic acid	affects expression	ISO	RGD:1622160	6480464	Valproic Acid affects the expression of UBXN8 mRNA	CTD	PMID:17292431
Ubxn8	Rat	valproic acid	decreases expression	ISO	RGD:1622160	6480464	Valproic Acid results in decreased expression of UBXN8 mRNA	CTD	PMID:21427059
Ubxn8	Rat	valproic acid	affects expression	ISO	RGD:1603319	6480464	Valproic Acid affects the expression of UBXN8 mRNA	CTD	PMID:25979313
Ubxn8	Rat	valproic acid	decreases expression	ISO	RGD:1603319	6480464	Valproic Acid results in decreased expression of UBXN8 mRNA	CTD	PMID:24935251\|PMID:29154799

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ubxn8	Rat	ERAD pathway	involved_in	ISO	RGD:1603319	1624291	PMID:21949850	RGD	PMID:21949850
Ubxn8	Rat	ERAD pathway	involved_in	IEA	InterPro:IPR017247	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ubxn8	Rat	endoplasmic reticulum	located_in	ISO	RGD:1603319\|UniProtKB:O00124-3	1624291		RGD	GO_REF:0000052
Ubxn8	Rat	endoplasmic reticulum	located_in	IEA	UniProtKB:A0A087WV67\|ensembl:ENSP00000479216	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ubxn8	Rat	endoplasmic reticulum membrane	located_in	ISO	RGD:1603319	1624291	PMID:21949850	RGD	PMID:21949850
Ubxn8	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ubxn8	Rat	nucleolus	located_in	ISO	RGD:1603319\|UniProtKB:O00124-3	1624291		RGD	GO_REF:0000052
Ubxn8	Rat	nucleolus	located_in	IEA	UniProtKB:A0A087WV67\|ensembl:ENSP00000479216	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ubxn8	Rat	nucleoplasm	located_in	ISO	RGD:1603319\|UniProtKB:O00124-3	1624291		RGD	GO_REF:0000052
Ubxn8	Rat	nucleoplasm	located_in	IEA	UniProtKB:A0A087WV67\|ensembl:ENSP00000479216	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ubxn8	Rat	protein binding	enables	ISO	RGD:1603319	1624291	UniProtKB:O15173\|UniProtKB:P14136\|UniProtKB:P48165\|UniProtKB:P55072\|UniProtKB:Q13520\|UniProtKB:Q6FHY5\|UniProtKB:Q7Z5P4\|UniProtKB:Q86TM6\|UniProtKB:Q9NUH8 PMID:18775313, PMID:21949850, PMID:29997244, PMID:32296183, PMID:32814053, PMID:35271311	RGD	PMID:18775313\|PMID:21949850\|PMID:29997244\|PMID:32296183\|PMID:32814053\|PMID:35271311
Ubxn8	Rat	ubiquitin binding	enables	IBA	PANTHER:PTN000594988\|PomBase:SPAC2C4.15c\|TAIR:locus:2132751\|UniProtKB:O94888\|UniProtKB:Q96CS3\|UniProtKB:Q9UNN5	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:21949850

Ubxn8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	65,239,149 - 65,260,743 (+)	NCBI		GRCr8
mRatBN7.2	16	58,536,086 - 58,557,684 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	58,536,086 - 58,557,684 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	63,873,647 - 63,895,266 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	67,287,312 - 67,308,931 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	62,507,878 - 62,529,497 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	62,251,243 - 62,272,838 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	62,251,243 - 62,272,838 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	61,911,951 - 61,933,546 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	62,308,482 - 62,330,075 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	62,309,492 - 62,328,941 (+)	NCBI
Celera	16	56,572,162 - 56,593,770 (+)	NCBI		Celera
Cytogenetic Map	16	q12.3	NCBI

UBXN8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	30,729,135 - 30,767,006 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	30,729,131 - 30,767,006 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	30,601,681 - 30,624,522 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	30,721,232 - 30,744,064 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	8	29,561,773 - 29,584,614 (+)	NCBI		Celera
Cytogenetic Map	8	p12	NCBI
HuRef	8	29,148,014 - 29,170,971 (+)	NCBI		HuRef
CHM1_1	8	30,803,863 - 30,825,966 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	31,008,589 - 31,048,026 (+)	NCBI		T2T-CHM13v2.0

Ubxn8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	34,109,614 - 34,135,515 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	34,109,614 - 34,131,995 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	33,619,586 - 33,645,476 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	33,619,586 - 33,641,967 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	34,730,058 - 34,752,448 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	35,085,521 - 35,107,911 (-)	NCBI		MGSCv36	mm8
Celera	8	36,253,546 - 36,278,148 (-)	NCBI		Celera
Cytogenetic Map	8	A4	NCBI
cM Map	8	20.65	NCBI

Ubxn8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955463	7,190,390 - 7,217,254 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955463	7,189,822 - 7,213,083 (+)	NCBI	ChiLan1.0	ChiLan1.0

UBXN8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	49,300,668 - 49,340,043 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	25,016,584 - 25,056,067 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	30,057,469 - 30,080,778 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	27,247,044 - 27,269,348 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	27,234,039 - 27,268,741 (+)	Ensembl	panpan1.1		panPan2

UBXN8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	16	33,590,905 - 33,622,752 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	16	33,591,273 - 33,679,673 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	16	34,050,244 - 34,145,336 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	35,616,980 - 35,711,899 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	35,616,283 - 35,648,690 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	16	33,715,579 - 33,810,676 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	16	34,288,046 - 34,382,336 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	34,406,943 - 34,501,444 (-)	NCBI		UU_Cfam_GSD_1.0

Ubxn8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	56,747,356 - 56,804,646 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936792	588,474 - 618,030 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936792	588,698 - 616,288 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBXN8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	54,339,563 - 54,367,605 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	54,342,575 - 54,367,610 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	61,714,643 - 61,740,032 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBXN8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	28,862,081 - 28,884,985 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	28,862,069 - 28,885,415 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	13,213,916 - 13,237,134 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ubxn8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624780	13,378,206 - 13,409,745 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Ubxn8
106 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	152
Count of miRNA genes:	107
Interacting mature miRNAs:	127
Transcripts:	ENSRNOT00000020347
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300163	Bmd64	Bone mineral density QTL 64	5.3	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	16	37752156	82752156	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
70215	Niddm29	Non-insulin dependent diabetes mellitus QTL 29	3.54		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	16	19004435	75226532	Rat
1578768	Stresp22	Stress response QTL 22	2.8		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	16	35288870	80288870	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	60252231	Rat
2302057	Pia29	Pristane induced arthritis QTL 29	3.6	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	16	21735975	66735975	Rat
7205510	Activ5	Activity QTL 5	3.78	0.00028	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	42396345	84729064	Rat
631525	Pia14	Pristane induced arthritis QTL 14	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	16	55711087	83402471	Rat
8694453	Bw172	Body weight QTL 172	8.33	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	16	24325513	69325513	Rat
7411648	Foco22	Food consumption QTL 22	15	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	52726464	84729064	Rat
1298529	Arunc1	Aerobic running capacity QTL 1	4		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	31951520	60148445	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	832236	59492508	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	832236	59492508	Rat
6903294	Stl30	Serum triglyceride level QTL 30	2.6	0.0013	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	16	25152793	70152793	Rat
2293690	Bss45	Bone structure and strength QTL 45	5.13	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	16	37752156	82752156	Rat
8694364	Abfw7	Abdominal fat weight QTL 7	12.22	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	16	52726464	84729064	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	832236	59492508	Rat
8694429	Bw164	Body weight QTL 164	5	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	16	52726464	84729064	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	832236	59492508	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001106086	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020347 ⟹ ENSRNOP00000020347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	58,536,086 - 58,557,684 (+)	Ensembl
Rnor_6.0 Ensembl	16	62,251,243 - 62,272,838 (+)	Ensembl

RefSeq Acc Id:

NM_001106086 ⟹ NP_001099556

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	65,239,149 - 65,260,743 (+)	NCBI
mRatBN7.2	16	58,536,086 - 58,557,684 (+)	NCBI
Rnor_6.0	16	62,251,243 - 62,272,838 (+)	NCBI
Rnor_5.0	16	61,911,951 - 61,933,546 (+)	NCBI
RGSC_v3.4	16	62,308,482 - 62,330,075 (+)	RGD
Celera	16	56,572,162 - 56,593,770 (+)	RGD

Sequence:

show sequence

CAAGACCAGAACCTCCTCAGGAGCAGTGGAGTTCGTTTACTGTTGCTGGGCTCTCTTCTCCTTACAGGTAGTGACTTCCTTGGAGAGTGAATTTTTATTTGCGAGTGGTTATCAATTGGAGATCATCT
GGGTTAGGGATGGAGAGAGGAGTCCACTTCTTTGGGCCCTAGGACCTTATCTGGTGACGATCCATGCAGGCCCTGTTCAGGCTGCCTCAGTTCTCCCAGTTCATGTTCATCGACCTTTTTTGATTTAG
AGGGCCTTGTCTTCTTGGTGTTCTTCATCCCTCTGGTTCTTAATCTTTCTGCCTCGGCTCTGAGGGGAGGAATTTGATAGACATCCATTTAGGGCTCACTGTTCCAAGGTCTCTCTCTCATGCTCTTC
TGTATACCTTTTCTCTCTCGTTAGTTTTTTTTTTTTTTTTTTTTTTTTGGTTGGTTTGTTTTTGTTTTTTTTTTTTCAACACAGGGTTTCTCTATGGAGATCCACCTGCCACTGCCTCCCTCGTGTAA
GAGTAAAGGCATACTCTAACCTTCACACTTCAGTCCGGAAATACTTCTCCACACTGCACAATGTGGTTCTGTAGCACTATATACACACATTCTTTATATCATGGCACCAGACATCATATAGTCTCTGT
ACAGGACATCTATCCCAGAGCTGAGTCTGTTCGGGGCAAAAACCAATGACTTACACATACTTGAAGCCAGGTACGCTGTGGGACATAATAAGTGGAACTTGAGTTAAACTTGAAACGTGATTGTGGTT
ATTGAGGGTTGAGGATTTGCAAAGTCAGTGGGGAGGCCCTCCACACCTGAGCTCTAAGTTACCAGAGCTGAGTCATGGAGTGAGAGTGAAGTCACTGTGAGGCCGAGGTTAAGTCATAACAGTAACAC
ATGTAGGCAAACTGACAGGGAGGACAGTAAGGGGGAGCAGGTCTAGGGGGATCTCCACGCGGGGGTGGGGCAGGAAAGGCATTCAGCAGCAGGCCCCACTTTTAAGCTTCTCGAAGGACCTGTTAGGG
AGAGAAGATGCTTAATAACTTGTAAGCTAGGAACCAAAAGCCCAGTTACCCCCAAGTGCCGCAAGGCCACGGGGCCTCGCAGAGTCAACTGCCCCTTTTAAGTCATTTCAGTCTTCTGAGTACCATCT
TTTAGACCTGCACAGTGGGACAATCCAGTCATCGCGGCCATCATCAGATCCACAGGACAAGGACCTCCCTGGACCTTCCCAGCCGAAAGAGATGACCCGCGCCGTCTGAGCACGGGCTATGGGTTTAT
CTCATTCAGGCCCACGCCCCAGCCTCAGGGCCTAAAATCCTCTCTCGGTCCCTCACAGCGGGAGCCCTCCGCTCCAAGCTCGCGGAAGGCACGGCCGGAAGGGGCGGCCCTACGCCCGGTGAATCCTT
CTCGCCATGGCTTCTCGTGGCGTCGTTGGCATTTTCTTGCTCTCTGCTCTCCCTCTCTTGTGTCTGGAGCTCCGGCGCGGGATCCCGAGTCTCGGAATTAAAGATCTCATTTTGCTCAGTGGCCGGGT
ATTCCTACTGCTGGCCCTGCTTACGATCGTCATTTCCGTGACCACCTCCTGGTTTAGCTCACTTAAACCTCCCCAAGTTCATCCGAAAGAAGGAGAAGAAGAGAATGCGAAAAGACAAAAACTCGCGA
GGGAGAGGCAACAAGAAGCCCAGGGTGAGAAGGCCAGCAGATATATACAGAATGTTTTAAAGCCTCAGCAGGAAATGAAGTTGAAAAAACTGGAAGAGCGGTTTTACCAGATGACGGGGGAGACCTGG
AAGCTGAGCACCGGCCACAGACTGGAGGAGGATGAAGATTCGGAGTTTGAAAATTCAAGTCAAGCGTCTTTTGAAACAGTTAACGGAGAGGCAGCAAGAAGACAGAACTTGCCTAAGTTTTTGACTGA
AATTTCACCACCCGCTCAGCCGCCCTCAAGGAAGGAGGTTCCTGACTTACCTGAAGAACCATCAGAAACAGCTGAAGGGGTGGTTACTGTTGCCCTCCGATGCCCAAGTGGACATCTTTTGAGGAGAA
GATTTTTCAAGTCGTGGAATTCACAGGTCTTATTTGACTGGATGATGAAAATTGGGTACCACAGATCCCTATACGGCCTCTCCACTTCCTTTCCCAGAAGGCCTTTGGAAGTGGGGGGAGGCTCGTCA
CTGGAGGACATAGGAATAACTGTGGATACTGTACTTAATGTGGAAGAGAGAGAGCAGAGCAGCCAGTAAGGAGAAGTACCTGAGTCCTTCAACACAGTGCTGTTCACAGTAAAGCCATGCTGTACCTT
GAGCTCCTCTTGTCCACAGGCGTGTACTGCGGATGAGGACCGCCATGTGATGGTGTGTGTCTCTGTCATCTTATAATGTGAAGAGGTAAAAAGCACATATCGTAAGACAGGCAGGCATCTGATGTTAC
TGCCTCAACTCCCAGGATTTCTGAGTTAATTAGACTATCTTCAAACCAAACCAAACCAAACCAAACCACACCACACCACACCACACCACACCCTAGCTTATGTAAGAACTATGATTTCTGCTTGAGTC
TACCTTACCATATACTATTTCACAATTCAGTCAAAATCTAAGGAGGAATGTAGATTCTATTGTATTTCTAAAAATTTAAAGAAATTCCACAGCCAACTGATCCTATATAATTTTGACTTAAATCTGGA
GATAAAGTTTGTATTACATGAACTTTGGGGAATATATTGAAACTGCAGTAAACAAGGCCATTGTTCTAAGTGCATTTGAAATGTGAGCTGTTGTTTGTGTGTGTACTGATGCCCTTAGCAGAGCATGT
CAACCTGTGGGGTCCTGTGGGGCTCCAAACAACCCTCTCACAGGGGTGCACCTAAGACCATCTGCAGTAGCAAAATTATTTTTTTTTCTTTTCTTTTTTTTGAAGCTGGGGACTGAACCCAGGGCCTT
GCGCTCGCTAGGCAAGCACTCTACCACTGAGCTAAATCCCCAACCCACAAAATTATTTATAAAGTAGCGACAAAATAATTTCATGGTTGGGTATTACCACAAATGAGGGCCTGTATTAAACAGCCTCA
GTATTACAGAGGTTGACAACTGCTGCCTTAGTCTGTCTTAAGGTATATTTCTTAATTTTTTTGGAGAGAGTTTCATGTAGCCTTGAATTTCCTGATCCTCTCCTGCCCCCTTCCAAGATCCTGGGATT
ACCAGGCTGAGCTACTGCATCCCGTTAATGAACCGGTAGACGGACCCTTGTGCCTCATCATGCACGGCAAGTACGCTATATCAATTGAGCTCCTTCCCAGGCCCCATGATTTCTATCCTTCAATTTCC
AAACTACCCAAGGCTCTACTTGTGGTGTGTGTCTTCAAATCACTCTACAGACAGATGTTAAGTAAACCCTGGCGATGGTATGCATGACCTCGGAATCTCATCATTACCACTGCTACTAAACAACAAAC
AGGTCAATTCCCACCTCTAGGTCAAAGGAGACAATCAGCTTTTAAAGTTTCTTGTGTTA

hide sequence


Protein RefSeqs	NP_001099556	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09141	(Get FASTA)	NCBI Sequence Viewer
	EDM09142	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020347.5
	ENSRNOP00000111844

RefSeq Acc Id:

NP_001099556 ⟸ NM_001106086

- UniProtKB:

D3ZUE3 (UniProtKB/TrEMBL), A6IVT0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASRGVVGIFLLSALPLLCLELRRGIPSLGIKDLILLSGRVFLLLALLTIVISVTTSWFSSLKPPQVHPKEGEEENAKRQKLARERQQEAQGEKASRYIQNVLKPQQEMKLKKLEERFYQMTGETWKL
STGHRLEEDEDSEFENSSQASFETVNGEAARRQNLPKFLTEISPPAQPPSRKEVPDLPEEPSETAEGVVTVALRCPSGHLLRRRFFKSWNSQVLFDWMMKIGYHRSLYGLSTSFPRRPLEVGGGSSLE
DIGITVDTVLNVEEREQSSQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000020347 ⟸ ENSRNOT00000020347

Protein Domains

UBX

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZUE3-F1-model_v2	AlphaFold	D3ZUE3	1-276	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13700141

Promoter ID:

EPDNEW_R10665

Type:

initiation region

Name:

Ubxn8_1

Description:

UBX domain protein 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	62,252,648 - 62,252,708	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-11119	BioCyc
Ensembl Genes	ENSRNOG00000015109	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00000091028	ENTREZGENE
Ensembl Transcript	ENSRNOT00000020347.6	UniProtKB/TrEMBL
	ENSRNOT00000165631	ENTREZGENE
Gene3D-CATH	Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1	UniProtKB/TrEMBL
InterPro	Ubiquitin-rel_dom	UniProtKB/TrEMBL
	UBX	UniProtKB/TrEMBL
	UBX_domain-protein	UniProtKB/TrEMBL
	UBXN8	UniProtKB/TrEMBL
KEGG Report	rno:290802	UniProtKB/TrEMBL
NCBI Gene	290802	ENTREZGENE
PANTHER	FAS-ASSOCIATED PROTEIN	UniProtKB/TrEMBL
	UBX DOMAIN-CONTAINING PROTEIN 8	UniProtKB/TrEMBL
Pfam	UBX	UniProtKB/TrEMBL
PhenoGen	Ubxn8	PhenoGen
PIRSF	UBX_Rep6	UniProtKB/TrEMBL
PROSITE	UBX	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000015109	RatGTEx
	ENSRNOG00000091028	RatGTEx
Superfamily-SCOP	SSF54236	UniProtKB/TrEMBL
UniProt	A6IVT0	ENTREZGENE, UniProtKB/TrEMBL
	A6IVT1_RAT	UniProtKB/TrEMBL
	D3ZUE3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-05-07	Ubxn8	UBX domain protein 8	Ubxd6	UBX domain containing 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ubxd6	UBX domain containing 6	Ubxd6_predicted	UBX domain containing 6 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Ubxd6_predicted	UBX domain containing 6 (predicted)	RGD1306023_predicted	similar to reproduction 8 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1306023_predicted	similar to reproduction 8 (predicted)	LOC290802_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC290802_predicted	similar to reproduction 8 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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