Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sec61a1 (SEC61 translocon subunit alpha 1) Rattus norvegicus
Symbol: Sec61a1
Name: SEC61 translocon subunit alpha 1
RGD ID: 68321
Description: Predicted to have ribosome binding activity; signal sequence binding activity; and transmembrane transporter activity. Involved in response to interferon-gamma. Localizes to rough endoplasmic reticulum. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human SEC61A1 (SEC61 translocon subunit alpha 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; phagocytosis pathway; INTERACTS WITH acrylamide; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: protein transport protein Sec61 subunit alpha; protein transport protein Sec61 subunit alpha isoform 1; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha subunit homolog; sec61 alpha-1; Sec61 translocon alpha 1 subunit; SEC61, alpha subunit; SEC61, alpha subunit (S. cerevisiae); Sec61a
Homo sapiens (human) : SEC61A1 (SEC61 translocon subunit alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Sec61a1 (Sec61 alpha 1 subunit (S. cerevisiae))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sec61a1 (SEC61 translocon alpha 1 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SEC61A1 (SEC61 translocon subunit alpha 1)
Canis lupus familiaris (dog) : SEC61A1 (SEC61 translocon subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sec61a1 (SEC61 translocon subunit alpha 1)
Sus scrofa (pig) : SEC61A1 (SEC61 translocon subunit alpha 1)
Chlorocebus sabaeus (African green monkey) : SEC61A1 (SEC61 translocon subunit alpha 1)
Heterocephalus glaber (naked mole-rat) : Sec61a1 (SEC61 translocon subunit alpha 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04120,453,577 - 120,467,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4120,453,581 - 120,467,932 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04185,693,504 - 185,707,859 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44122,597,889 - 122,612,245 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14122,842,369 - 122,856,726 (-)NCBI
Celera4109,929,352 - 109,943,708 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Sec61a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68321
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.