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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:brain ischemia
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Accession:DOID:2316 term browser browse the term
Definition:An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand. (DO)
Synonyms:exact_synonym: Cerebral Hypoperfusion;   Cerebral Ischemias;   Ischaemic encephalopathy;   brain ischemias;   cerebral ischemia;   ischemic encephalopathies;   ischemic encephalopathy
 primary_id: MESH:D002545
 xref: EFO:0003883;   MONDO:0005299
For additional species annotation, visit the Alliance of Genome Resources.


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brain ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, sub-family B member 1B IEP RGD PMID:15049514 RGD:1598554 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:15534175 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP mRNA:increased expression:brain RGD PMID:17073862 RGD:9681750 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Add3 adducin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Adk adenosine kinase ISO RGD PMID:21427729 PMID:17457365 RGD:6482652, RGD:6482655 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP mRNA:increased expression:pyramidal cell, hippocampus RGD PMID:12618340 RGD:1625348 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:cerebral cortex (rat) RGD PMID:18301954 RGD:2313032 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akap1 A-kinase anchoring protein 1 IEP protein:altered expression:parietal cortex, hippocampus (rat) RGD PMID:18323779 RGD:2313128 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896 		JBrowse link
G Akap12 A-kinase anchoring protein 12 IEP RGD PMID:21334414 RGD:14348963 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IEP protein:decreased serine phosphorylation:cerebral cortex RGD PMID:21596097 RGD:5509066 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: therapeutic CTD PMID:16809570 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase IEP mRNA, protein:increased expression:brain RGD PMID:20167207 RGD:5509598 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20204486 RGD:2317525 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Angpt1 angiopoietin 1 ISO RGD PMID:17637706 RGD:1643339 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Angpt2 angiopoietin 2 IDA RGD PMID:17494864 RGD:2314206 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Anxa1 annexin A1 treatment ISO
IMP		 RGD PMID:1830327 PMID:1830327 RGD:7421662, RGD:7421662 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 IEP protein:increased expression:striatum RGD PMID:17640469 RGD:2325742 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:decreased expression:hippocampus CA1, neuron RGD PMID:9030714 RGD:2315686 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) IEP RGD PMID:19616516 RGD:5490152 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:19616516 RGD:5490152 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp5 aquaporin 5 IEP RGD PMID:19616516 RGD:5490152 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Aqp8 aquaporin 8 IEP RGD PMID:19616516 RGD:5490152 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21307247 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541 		JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:decreased serine phosphorylation:brain RGD PMID:18078455 PMID:22843461 RGD:2292681, RGD:10053716 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bbc3 Bcl-2 binding component 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19095966 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA RGD PMID:15585409 RGD:11522731 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 IEP protein:increased expression:cerebral cortex RGD PMID:17706879 PMID:22843461 RGD:1643491, RGD:10053716 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19922383 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 IMP
IEP		 protein:increased expression:hippocampus, frontal cortex RGD PMID:19574998 PMID:17936001 RGD:6483094, RGD:6483313 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP RGD PMID:11245809 RGD:2289024 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:forebrain (rat) RGD PMID:7684483 RGD:2289081 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C3 complement C3 IEP protein:increased expression:brain RGD PMID:14561876 RGD:5129543 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp12 caspase 12 IEP mRNA, protein:increased expresssion:brain RGD PMID:12598725 RGD:1299333 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 PMID:17901229 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 IEP mRNA:increased expression:cerebral cortex RGD PMID:11311984 RGD:2301331 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp9 caspase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cast calpastatin IDA RGD PMID:16467455 RGD:5509813 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17564305 PMID:21213399 RGD:5130891 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 IEP RGD PMID:16417587 RGD:1581152 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15829914 PMID:17394460 PMID:19260320 RGD:2306998 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IEP mRNA:increased expression:cerebral cortex RGD PMID:9916893 RGD:69987 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 PMID:17394460 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:brain (rat) RGD PMID:9670989 RGD:632396 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:20360550 RGD:6893498 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 IMP RGD PMID:14502288 RGD:734740 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17394460 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18501976 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 IEP RGD PMID:16434029 RGD:1581188 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Clu clusterin IEP RGD PMID:12782389 RGD:727237 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cp ceruloplasmin IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus RGD PMID:18273071 RGD:2314688 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP mRNA,protein:decreased expression,decreased phosphorylation:brain: RGD PMID:23644141 RGD:10059580 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:8541482 RGD:1581300 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta IEP mRNA:increased expression:brain RGD PMID:7643220 RGD:632531 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Csf3 colony stimulating factor 3 ISO associated with Diabetes Mellitus, Experimental RGD PMID:18832793 RGD:2311241 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IEP RGD PMID:21864831 RGD:5686850 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Cst3 cystatin C ISO protein:decreased expression:cerebrospinal fluid RGD PMID:18261165 RGD:2314349 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:cerebrum (rat) RGD PMID:18404379 RGD:2315571 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsc cathepsin C IEP mRNA:increased expression:cerebral cortex RGD PMID:12843783 RGD:1599640 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsl cathepsin L IEP protein:increased activity:cerebrum (rat) RGD PMID:18404379 RGD:2315571 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP
ISO		 mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15829914 PMID:17549754 RGD:2311381 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP mRNA, protein:increased expression:brain RGD PMID:18206136 RGD:2306577 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cycs cytochrome c, somatic ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Dbh dopamine beta-hydroxylase IEP protein:decreased expression:forebrain (rat) RGD PMID:18356740 RGD:5129691 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IEP Protein:increased expression:brain RGD PMID:15921666 RGD:1599731 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:11756504 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 IEP mRNA:increased expression:brain RGD PMID:19524114 RGD:2316241 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Drd2 dopamine receptor D2 IEP RGD PMID:11474153 RGD:1580883 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dusp6 dual specificity phosphatase 6 IEP mRNA:increased expression:brain RGD PMID:10908038 RGD:2316092 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9522364 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Edn1 endothelin 1 IEP protein:increased expression:cerebral cortex (rat) RGD PMID:8113329 RGD:4144887 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egr1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17394460 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Endog endonuclease G IEP RGD PMID:18568342 RGD:9685367 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Epor erythropoietin receptor IEP protein:increased expression:brain: RGD PMID:14732457 RGD:11041652 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Esr2 estrogen receptor 2 IEP mRNA:decreased expression:cerebral cortex, ipsilateral side (rat) RGD PMID:10414967 RGD:8694344 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14753426 PMID:15534175 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F2r coagulation factor II (thrombin) receptor IEP RGD PMID:14705148 RGD:1302269 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F5 coagulation factor V ISO CTD Direct Evidence: marker/mechanism CTD PMID:15534175 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G Fas Fas cell surface death receptor IEP protein:increased expression:brain RGD PMID:16796407 RGD:1600333 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand IEP protein:increased expression:brain RGD PMID:18410517 RGD:2311437 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fga fibrinogen alpha chain treatment IDA RGD PMID:22737923 RGD:11040923 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgf1 fibroblast growth factor 1 IDA
ISO		 Rat model using human FGF1 RGD PMID:19497570 PMID:16635575 RGD:5509879, RGD:5509881 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Gal galanin and GMAP prepropeptide IEP RGD PMID:16458372 RGD:1624341 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gc GC, vitamin D binding protein IEP protein:increased expression:urine RGD PMID:11239198 RGD:1625796 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 IEP protein:increased expression:cerebral cortex RGD PMID:10407114 RGD:6218981 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gja1 gap junction protein, alpha 1 IEP protein:increased expression:cerebral cortex RGD PMID:21718970 RGD:6480433 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:decreased activity:brain RGD PMID:7808037 RGD:6484655 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha exacerbates ISO associated with Pneumococcal Infections RGD PMID:24644058 RGD:42722626 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:12531513 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:increased expression:plasma RGD PMID:30025402 RGD:401827828 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO
IDA
IEP		 protein:increased expression:brain
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:cerebral cortex (rat)		 CTD
RGD		 PMID:19429140 PMID:17554006 PMID:18369388 PMID:17101276 RGD:1626331, RGD:9068895, RGD:9068892 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 IEP
IMP		 RGD PMID:16464361 PMID:21276833 RGD:1582709, RGD:10755576 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO associated with advanced age and Diabetes Mellitus, Type 2 (MeSH:D003924) RGD PMID:15992611 RGD:1626649 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:16805800 RGD:6480229 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 IEP mRNA:increased expression:brain RGD PMID:7629893 RGD:6784525 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17394460 PMID:19417757 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igf1 insulin-like growth factor 1 IDA
ISO		 RGD PMID:16882007 PMID:19332057 RGD:1598411, RGD:2306694 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769 		JBrowse link
G Il17a interleukin 17A IEP
ISO		 protein, mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism
protein:increased expression:brain		 CTD
RGD		 PMID:15829914 PMID:16305645 PMID:16305645 RGD:4846398, RGD:4846398 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17ra interleukin 17 receptor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174 		JBrowse link
G Il18 interleukin 18 IEP
ISO		 mRNA:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15829914 PMID:11807395 RGD:4889510 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:9236716 PMID:15737438 PMID:15756928 PMID:17394460 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:9236716 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 PMID:17394460 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer IEP mRNA:increased expression:brain, astrocyte RGD PMID:15469886 RGD:1627568 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:21925238 RGD:7495802 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:21925238 RGD:7495802 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Itgam integrin subunit alpha M IEP associated with Hypotension;protein:increased expression:pyramidal layer of CA1 (rat) RGD PMID:19019197 RGD:329853772 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnk10 potassium two pore domain channel subfamily K member 10 IEP mRNA, protein:increased expression:cerebral cortex, hippocampus (rat) RGD PMID:15652517 RGD:9831167 NCBI chr 6:117,690,052...117,826,120
Ensembl chr 6:117,694,222...117,825,695 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IEP mRNA:increased expression:hippocampus (rat) RGD PMID:14741413 RGD:9831127 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:18951929 RGD:5684407 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lgals3 galectin 3 IEP RGD PMID:10931529 RGD:9685227 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lif LIF, interleukin 6 family cytokine IEP mRNA:increased expression:brain RGD PMID:20221422 RGD:2326053 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial IDA RGD PMID:12082077 RGD:633879 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Map2 microtubule-associated protein 2 IEP protein:increased expression:serum RGD PMID:21948028 RGD:6483082 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17901229 PMID:10536014 RGD:1582169 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 treatment ISO RGD PMID:21475303 RGD:155882442 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17901229 PMID:15669185 RGD:1582281 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:15797868 RGD:1582325 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapt microtubule-associated protein tau IDA protein:increased phosphorylation RGD PMID:15353210 RGD:1599927 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mdh2 malate dehydrogenase 2 IDA RGD PMID:6282622 RGD:1582465 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Mdk midkine ISO RGD PMID:12127679 RGD:1582476 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mir223 microRNA 223 treatment IMP RGD PMID:31791013 RGD:26884340 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:16112096 RGD:1582554 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP RGD PMID:15963646 RGD:1582577 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:15963646 RGD:1582577 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15060315 PMID:16846501 RGD:1582611 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19417757 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Msi1 musashi RNA-binding protein 1 IEP RGD PMID:12205668 RGD:633285 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15534175 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 IEP protein:increased expression:thalamus (rat) RGD PMID:9288726 RGD:2317254 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nes nestin IEP protein:increased expression:hippocampus RGD PMID:17697621 RGD:1642071 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO CTD Direct Evidence: therapeutic CTD PMID:18628779 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18628779 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos1 nitric oxide synthase 1 IMP
IEP		 protein:decreased expression:hippocampus RGD PMID:17451676 PMID:21718970 RGD:1642142, RGD:6480433 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9778187 PMID:17394460 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 IDA
IMP		 RGD PMID:21212863 PMID:17600658 RGD:4891961, RGD:2292134 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox4 NADPH oxidase 4 ISO mRNA, protein:increased expression:cerebral cortex (human) RGD PMID:15802177 RGD:1580980 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nppa natriuretic peptide A no_association ISO RGD PMID:11706124 RGD:1626244 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nptxr neuronal pentraxin receptor IEP mRNA:decreased expression:neocortex RGD PMID:12242102 RGD:1642302 NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP protein:decreased expression:brain cortex RGD PMID:17344647 RGD:4892115 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 IEP mRNA:altered expression:cerebral cortex (rat) RGD PMID:19531214 RGD:401851038 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310 		JBrowse link
G Oprm1 opioid receptor, mu 1 IEP RGD PMID:16176345 RGD:2316630 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IEP protein:increased expression:brain RGD PMID:17997827 RGD:2299171 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17640816 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen IEP protein:increased expression:brain RGD PMID:12099899 RGD:729592 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pgf placental growth factor ISO RGD PMID:16901914 RGD:6483783 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685 		JBrowse link
G Pla2g4a phospholipase A2 group 4A IEP mRNA:increased expression:hippocampus RGD PMID:15306117 RGD:1642465 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plat plasminogen activator, tissue type no_association ISO DNA:polymorphism:-7351C>T (human)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:7477192 PMID:9259745 PMID:9400355 PMID:9479658 PMID:9566367 More... RGD:1580879 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:9731615 PMID:10472989 PMID:10512912 PMID:17927297 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Ppbp pro-platelet basic protein ISO RGD PMID:26307429 RGD:11553187 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130 		JBrowse link
G Ppid peptidylprolyl isomerase D ISO RGD PMID:16103352 RGD:1580699 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IEP protein:increased expression:cerebral cortex, caudate nucleus (rat) RGD PMID:15713259 RGD:9999408 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEP protein:decreased expression:hippocampus, cerebral cortex, nucleus RGD PMID:12150772 RGD:7327190 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEP protein:decreased expression:hippocampus, cerebral cortex, cytosol, nucleus RGD PMID:12150772 RGD:7327190 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkca protein kinase C, alpha IEP associated with Subarachnoid Hemorrhage;protein:increased phosphorylation:cerebral artery RGD PMID:18032736 RGD:2293301 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:17350602 RGD:1642524 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Proz protein Z, vitamin K-dependent plasma glycoprotein ISO RGD PMID:14671240 RGD:1358564 NCBI chr16:76,450,013...76,463,558
Ensembl chr16:76,450,013...76,463,480 		JBrowse link
G Ptgis prostaglandin I2 synthase IDA RGD PMID:16094316 RGD:8693629 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO protein:increased expression:microglia, macrophage RGD PMID:11740205 PMID:10867793 RGD:5688240, RGD:5688247 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO
IDA		 protein:increased expression:hippocampus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15737438 PMID:17394460 PMID:17564305 PMID:19417757 PMID:21718970 More... RGD:6480433, RGD:5688292, RGD:1581286 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IDA protein:increased tyrosine phosphorylation:cerebral cortex RGD PMID:10964954 RGD:1642647 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: therapeutic CTD PMID:18628779 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ret ret proto-oncogene IEP protein:increased expression:cerebral cortex RGD PMID:10407114 RGD:6218981 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:serum RGD PMID:21695352 RGD:5508764 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IEP RGD PMID:19471098 RGD:6484225 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Sele selectin E ISO associated with Hypertension
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17394460 PMID:19107136 RGD:2313600 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:27108052 RGD:11073613 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 IEP protein:increased expression:brain RGD PMID:21325818 RGD:5688411 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 IMP RGD PMID:15829178 RGD:2316942 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 IMP RGD PMID:15084665 RGD:1643209 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP
IMP		 protein:increased expression:brain
mRNA:decreased expression:cerebral cortex (rat)		 RGD PMID:17662498 PMID:22036625 PMID:12377375 RGD:1642717, RGD:6771236, RGD:727449 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 IEP RGD PMID:16107787 RGD:2316979 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 IEP RGD PMID:16107787 RGD:2316979 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:11756504 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15060315 PMID:17901229 PMID:19429140 PMID:10212301 RGD:1625695 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:10833313 RGD:1580852 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 IDA RGD PMID:26442853 RGD:155630597 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IDA RGD PMID:15854740 RGD:1581411 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17901229 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tek TEK receptor tyrosine kinase IEP RGD PMID:11919509 RGD:634324 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP mRNA:increased expression:brain RGD PMID:14997937 RGD:2302105 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase IEP protein:decreased expression:solitary tract nucleus, medulla oblongata, locus coeruleus (rat) RGD PMID:18356740 RGD:5129691 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tjp1 tight junction protein 1 IEP protein:decreased expression:brain RGD PMID:19712057 RGD:2325131 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tlr4 toll-like receptor 4 no_association ISO DNA:polymorphisms: :p.N299G, p.T399I (human) RGD PMID:15258789 RGD:1580737 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15756928 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15829914 PMID:16442237 RGD:1624184 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tp53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19095966 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ttr transthyretin IEP RGD PMID:15469881 RGD:1580523 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ucp2 uncoupling protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17052689 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Vip vasoactive intestinal peptide IDA RGD PMID:18158987 RGD:5685617 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta IEP protein:increased expression:cerebrospinal fluid RGD PMID:15902199 RGD:2306031 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105 		JBrowse link
Brain Hypoxia-Ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2b activin A receptor type 2B severity ISO mRNA, protein:increased expression:umbilical cord blood (human) RGD PMID:27957679 RGD:329849106 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Ada adenosine deaminase IEP protein:increased activity:brain: RGD PMID:25720338 RGD:152995398 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adk adenosine kinase IEP protein:decreased expression:brain: RGD PMID:25720338 RGD:152995398 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Adnp activity-dependent neuroprotector homeobox IDA RGD PMID:16938277 RGD:2312775 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312 		JBrowse link
G Adora1 adenosine A1 receptor IEP protein:decreased expression:brain: RGD PMID:25720338 RGD:152995398 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:22569153 RGD:6903872 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:right cerebral hemisphere (rat) RGD PMID:19447505 RGD:2313021 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP protein:increased expression:nucleus: RGD PMID:12871572 PMID:28108258 RGD:10053564, RGD:13524865 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21189961 PMID:24089674 PMID:29635023 RGD:10054502, RGD:155882465, RGD:13782292 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcan brevican IEP RGD PMID:15817274 RGD:14392799 NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:21189961 PMID:24089674 PMID:29635023 RGD:10054502, RGD:155882465, RGD:13782292 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 IDA RGD PMID:24195677 RGD:10053669 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:cerebral cortex
protein:increased expression:brain		 RGD PMID:22449108 PMID:25919564 RGD:6483050, RGD:11558017 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 IEP protein:increased expression:pineal gland RGD PMID:23336172 RGD:10043348 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IEP mRNA,protein:decreased expression:brain: RGD PMID:23236544 RGD:8699519 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Casp1 caspase 1 IEP RGD PMID:23046993 RGD:13782359 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 IDA protein:increased activity:cerebral cortex, hippocampus RGD PMID:18603371 RGD:2311455 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 treatment IDA
IEP		 protein:increased activity:cerebral cortex, hippocampus RGD PMID:18603371 PMID:24089674 PMID:23046993 PMID:29635023 PMID:27216999 More... RGD:2311455, RGD:155882465, RGD:13782359, RGD:13782292, RGD:13782279, RGD:10054502 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:29635023 PMID:23046993 RGD:13782292, RGD:13782359 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:23046993 PMID:24089674 RGD:13782359, RGD:155882465 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cast calpastatin IEP RGD PMID:10318818 RGD:5683321 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase treatment ISO RGD PMID:21978706 RGD:9068474 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP protein:increased expression:forebrain (rat) RGD PMID:9270493 RGD:8549543 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 IEP mRNA, protein:increased expression:brain RGD PMID:18095591 RGD:4144890 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IEP mRNA:increased expression:cerebral hemisphere (rat) RGD PMID:16516309 RGD:4890442 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 treatment IMP RGD PMID:25665755 RGD:13782373 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Clock clock circadian regulator IEP protein:increased expression:pineal gland RGD PMID:23336172 RGD:10043348 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase IEP RGD PMID:19747899 RGD:6483337 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Crp C-reactive protein ISO RGD PMID:20220110 RGD:9585994 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cs citrate synthase treatment IDA RGD PMID:15132986 PMID:15569775 RGD:243048479, RGD:243048481 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Csf1r colony stimulating factor 1 receptor exacerbates IMP
IEP		 protein:increased expression:right cerebral hemisphere, astrocyte, neuron (rat) RGD PMID:32522286 PMID:33101590 RGD:151665765, RGD:151665766 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IEP mRNA:increased expression:brain RGD PMID:17549754 RGD:2311381 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:21843499 RGD:9587791 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha IEP protein:decreased expression:brain: RGD PMID:23716065 RGD:9588620 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Egr1 early growth response 1 IEP mRNA:increased expression:forebrain (rat) RGD PMID:7684483 RGD:2289081 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:8092984 RGD:10395352 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Epha4 Eph receptor A4 IEP protein:increased expression:brain RGD PMID:21736568 RGD:5688765 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Epo erythropoietin treatment IEP
ISO		 RGD PMID:24034924 PMID:22156696 RGD:10400911, RGD:10401072 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha IEP mRNA:increased expression:hippocampus RGD PMID:12694393 RGD:632668 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:29635023 RGD:13782292 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor IEP RGD PMID:21843499 RGD:9587791 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP protein:decreased expression:hippocampus RGD PMID:25262910 RGD:405650622 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxo3 forkhead box O3 IEP protein:increased expression:cerebral cortex,nucleus: RGD PMID:24229603 RGD:10402203 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fst follistatin IEP mRNA:decreased expression:brain (rat) RGD PMID:10415398 RGD:329322882 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Ghr growth hormone receptor IEP protein:increased expression:brain RGD PMID:19524466 RGD:2315620 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:19761817 RGD:2325954 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:19761817 RGD:2325954 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:19761817 RGD:2325954 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gsn gelsolin severity ISO protein:decreased expression:blood plasma (human) RGD PMID:29466895 RGD:329333029 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP mRNA:decreased expression:hippocampus,cortex: RGD PMID:19892002 RGD:9686395 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hdac3 histone deacetylase 3 IEP protein:decreased expression:brain: RGD PMID:23716065 RGD:9588620 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
ISO
IDA		 protein:increased expression:brain (rat)
mRNA, protein:increased expression:brain,kidney (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23694759 PMID:18210138 PMID:31784544 PMID:19595151 RGD:9068873, RGD:155882534, RGD:9068901 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:25447631 RGD:10766440 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A IEP RGD PMID:22526757 RGD:7257595 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Igf1 insulin-like growth factor 1 treatment ISO
IDA
IEP		 RGD PMID:11672597 PMID:23694759 PMID:19766709 RGD:8549456, RGD:12904932, RGD:10046049 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 disease_progression ISO RGD PMID:16787587 RGD:5510005 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 IEP RGD PMID:10709766 RGD:10402756 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:brain (rat) RGD PMID:23110519 RGD:7204438 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 severity ISO DNA:polymorphism: :174G>C(human) RGD PMID:22117975 RGD:12792241 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A severity
treatment		 IEP
ISO		 mRNA:increased expression:brain (rat)
mRNA, protein:increased expression:umbilical cord blood (human)
human construct in rat model		 RGD PMID:10415398 PMID:27957679 PMID:10415398 RGD:329322882, RGD:329849106, RGD:329322882 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21925238 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak4 interleukin-1 receptor-associated kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21925238 NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837 		JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP mRNA:increased expression:brain (rat) RGD PMID:27602087 RGD:12903962 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:21277350 RGD:5684383 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:25919564 RGD:11558017 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map2 microtubule-associated protein 2 IDA RGD PMID:21300124 RGD:6483088 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP RGD PMID:21843499 RGD:9587791 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ameliorates ISO
IEP		 protein:increased expression:brain (rat) RGD PMID:29138854 PMID:32734729 RGD:155804273, RGD:155804275 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapt microtubule-associated protein tau treatment IDA RGD PMID:25665755 RGD:13782373 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IEP protein:increased expression:brain: RGD PMID:23716065 RGD:9588620 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mbp myelin basic protein IEP protein:decreased expression:white matter: RGD PMID:23715956 RGD:7327196 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mir140 microRNA 140 severity ISO miRNA:decreased expression:blood serum (human) RGD PMID:34331407 RGD:329347831 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir17 microRNA 17 ISO RGD PMID:35085690 RGD:329349305 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir210 microRNA 210 treatment
disease_progression		 IMP
ISO		 miRNA:decreased expression:blood serum (human)
associated with Brain Injuries;miRNA:increased expression:brain, cerebral hemisphere (human)		 RGD PMID:26875527 PMID:24089674 PMID:29568675 PMID:33402183 RGD:11572290, RGD:155882465, RGD:155598592, RGD:155582222 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mmp3 matrix metallopeptidase 3 treatment IEP RGD PMID:21038694 RGD:8694100 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mpo myeloperoxidase IEP protein:increased activity:brain: RGD PMID:25720338 RGD:152995398 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase IEP protein:increased activity:brain: RGD PMID:25720338 RGD:152995398 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23694759 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nrf1 nuclear respiratory factor 1 IEP mRNA, protein:increase expression:cerebral cortex RGD PMID:18723421 RGD:2302400 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IEP mRNA:increased expression:brain RGD PMID:19633950 RGD:5684358 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP RGD PMID:10215166 RGD:10449494 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Plat plasminogen activator, tissue type onset IEP RGD PMID:18467699 RGD:6483831 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase IDA
IEP		 mRNA, protein:increased expression, increased activity:hippocampus (rat) RGD PMID:19587273 PMID:18467699 RGD:2316117, RGD:6483831 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B IEP RGD PMID:23153068 RGD:13515077 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit treatment IMP RGD PMID:30485360 RGD:39938998 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prkdcem1Sage protein kinase, DNA-activated, catalytic subunit; ZFN induced mutant 1, Sage treatment IMP RGD PMID:30485360 RGD:39938998
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IEP STEP33;protein:increased expression:forebrain (rat) RGD PMID:10537057 RGD:9835021 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IEP RGD PMID:16041802 RGD:9590116 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G Rnf146 ring finger protein 146 IEP RGD PMID:28108258 RGD:13524865 NCBI chr 1:28,458,864...28,475,758
Ensembl chr 1:28,458,887...28,475,923 		JBrowse link
G Robo1 roundabout guidance receptor 1 exacerbates IMP RGD PMID:31356825 RGD:242905191 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G S100b S100 calcium binding protein B severity ISO associated with Asphyxia Neonatorum;protein:increased expression:urine
protein:increased expression:blood serum (human)		 RGD PMID:14707571 PMID:29568675 RGD:5508819, RGD:155598592 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:19587273 RGD:2316117 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP RGD PMID:20883671 RGD:6771331 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Slit2 slit guidance ligand 2 treatment IEP RGD PMID:31356825 RGD:242905191 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Spi1 Spi-1 proto-oncogene IEP protein:increased expression:CA1 field of hippocampus RGD PMID:10713349 RGD:9586724 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Srgap1 SLIT-ROBO Rho GTPase activating protein 1 exacerbates IMP RGD PMID:31356825 RGD:242905191 NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196 		JBrowse link
G Tert telomerase reverse transcriptase treatment IDA RGD PMID:21940960 RGD:11038672 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tf transferrin treatment ISO RGD PMID:22736466 RGD:7244383 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfam transcription factor A, mitochondrial IEP mRNA:increased expression:cerebral cortex RGD PMID:18723421 RGD:2302400 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:28139935 RGD:15090829 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 IEP mRNA:increased expression:glomerular podocytes (rat) RGD PMID:31784544 RGD:155882534 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:23694759 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 IEP
IMP		 mRNA:increased expression:glomerular podocytes (rat) RGD PMID:31784544 PMID:34852714 RGD:155882534, RGD:155882542 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
brain infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing IDA RGD PMID:19362080 RGD:5686830 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adk adenosine kinase ISO
IMP		 RGD PMID:16685255 PMID:9731623 RGD:6482657, RGD:6482667 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Adm adrenomedullin treatment ISO RGD PMID:21695352 RGD:5508764 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adnp activity-dependent neuroprotector homeobox IDA RGD PMID:11935065 RGD:1358226 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312 		JBrowse link
G Aif1 allograft inflammatory factor 1 IEP
ISO		 protein:increased expression:brain subventricular zone (rat)
protein:increased expression:brain white matter (human)		 RGD PMID:19053043 PMID:10683518 RGD:2313025, RGD:2313026 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO RGD PMID:17388993 RGD:1601161 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO associated with Metabolic Syndrome X; DNA:polymorphism:g.162A>C rs4769055 (human) RGD PMID:18506375 RGD:2311309 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Arrb2 arrestin, beta 2 IEP protein:increased expression:spleen RGD PMID:29636059 RGD:401938621 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 IEP mRNA:decreased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:22227058 RGD:6483057 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IEP mRNA:decreased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Calcrl calcitonin receptor like receptor IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910 		JBrowse link
G Cd8a CD8 subunit alpha IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040 		JBrowse link
G Cfh complement factor H treatment ISO RGD PMID:21695352 RGD:5508764 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cort cortistatin IEP mRNA:decreased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Ctsb cathepsin B IEP protein:increased expression:cerebral cortical segment, cytoplasm (rat) RGD PMID:19941836 RGD:2315502 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP protein:increased expression:brain (rat) RGD PMID:19895873 RGD:2325193 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19417757 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 IEP mRNA:decreased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO DNA:variants:CDS:multiple (human) RGD PMID:36762557 RGD:401901151 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Dcx doublecortin IEP protein:altered expression:brain (rat) RGD PMID:12161747 RGD:155630606 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:15485550 RGD:1580908 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:17524524 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Gpnmb glycoprotein nmb IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr17 G protein-coupled receptor 17 ISO CTD Direct Evidence: therapeutic CTD PMID:18974869 NCBI chr18:23,576,232...23,583,153
Ensembl chr18:23,577,242...23,582,966 		JBrowse link
G Gzmb granzyme B IEP protein:increased expression:brain (rat) RGD PMID:19895873 RGD:2325193 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Hgf hepatocyte growth factor treatment IDA RGD PMID:16421510 RGD:8548626 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha exacerbates IMP RGD PMID:30052311 RGD:155663378 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 IMP RGD PMID:19944723 RGD:2316741 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hnmt histamine N-methyltransferase severity IMP RGD PMID:21131122 PMID:16330002 RGD:5509772, RGD:5509773 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:18692933 RGD:2313474 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA, protein:increased expression:brain RGD PMID:7770004 RGD:5509999 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Il15 interleukin 15 ISO associated with Hypertension;protein:increased expression:serum RGD PMID:16109314 RGD:1626610 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:cerebral cortex (rat) RGD PMID:17678971 RGD:1626644 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 IEP protein:increased expression:brain (rat) RGD PMID:19895873 RGD:2325193 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 1:84,525,613...84,533,948
Ensembl chr 1:84,525,590...84,534,677 		JBrowse link
G Mdk midkine IDA RGD PMID:15450683 RGD:1582478 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Meis2 Meis homeobox 2 IEP protein:altered expression:brain (rat) RGD PMID:12161747 RGD:155630606 NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696 		JBrowse link
G Mgp matrix Gla protein IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667 		JBrowse link
G Mir223 microRNA 223 IEP RNA:increased expression:brain,blood RGD PMID:31342956 RGD:25824952 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mmp14 matrix metallopeptidase 14 IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp8 matrix metallopeptidase 8 IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO RGD PMID:16599837 RGD:1582617 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Msi1 musashi RNA-binding protein 1 IEP RGD PMID:15250238 RGD:1582664 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076 		JBrowse link
G Nes nestin IEP associated with Hypertension RGD PMID:16321245 RGD:1642069 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase IMP associated with Reperfusion Injury RGD PMID:12834903 RGD:2316742 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Pbx1 PBX homeobox 1 IEP protein:altered expression:brain (rat) RGD PMID:12161747 RGD:155630606 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IMP RGD PMID:14980813 RGD:1581758 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: therapeutic CTD PMID:16190367 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B IEP protein:altered expression:brain (rat) RGD PMID:12161747 RGD:155630606 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Prcp prolylcarboxypeptidase IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 1:146,931,487...146,983,891
Ensembl chr 1:146,930,561...146,984,530 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 IEP protein:altered expression:brain (rat) RGD PMID:12161747 RGD:155630606 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935 		JBrowse link
G RT1-Ba RT1 class II, locus Ba ISO DNA:polymorphisms (human) RGD PMID:11798899 RGD:5147807 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22878646 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA RGD PMID:14650360 RGD:1601455 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096 		JBrowse link
G Tnf tumor necrosis factor IEP protein:increased expression:brain (rat) RGD PMID:19895873 RGD:2325193 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tpcn2 two pore segment channel 2 IEP mRNA:increased expression:brain (rat) RGD PMID:23251410 RGD:329845556 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236 		JBrowse link
Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htra1 HtrA serine peptidase 1 ISO ClinVar Annotator: match by term: CARASIL | ClinVar Annotator: match by term: CARASIL syndrome | ClinVar Annotator: match by term: Cerebrovascular disease with thin skin, alopecia, and disc disease | ClinVar Annotator: match by term: HTRA1-related cerebral small vessel disease
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:11889251 PMID:18316707 PMID:19387015 PMID:20437615 PMID:21115960 More... NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Pura purine rich element binding protein A ISO ClinVar Annotator: match by term: Cerebrovascular disease with thin skin, alopecia, and disc disease ClinVar PMID:24500651 PMID:25342064 NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513 		JBrowse link
cerebral infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin disease_progression ISO RGD PMID:28266892 RGD:13702087 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Ace angiotensin I converting enzyme ISO DNA:deletion:intron:IVS16+1464-1751del (human)
ClinVar Annotator: match by term: Ischemic stroke, susceptibility to		 ClinVar
RGD		 PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... RGD:11038922 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adora1 adenosine A1 receptor IDA RGD PMID:17067559 RGD:1625229 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO protein:increased expression:plasma RGD PMID:23288172 RGD:8696004 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 onset ISO DNA:missense mutation:cds:V498L (rs16899974) (human) RGD PMID:26984639 RGD:329961314 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
G Ahsp alpha hemoglobin stabilizing protein ISO mRNA:increased expression:venous blood (human) RGD PMID:29284304 RGD:329961296 NCBI chr 1:182,879,901...182,885,508
Ensembl chr 1:182,880,076...182,885,506 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein susceptibility ISO OMIM NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Ang angiogenin severity ISO protein:increased expression:serum RGD PMID:17823536 RGD:6892714 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Anxa1 annexin A1 treatment IEP associated with Ischemic Attack, Transient RGD PMID:22617647 RGD:7483559 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apoa5 apolipoprotein A5 ISO associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :-1131T>C (human) RGD PMID:19107359 RGD:2313314 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816 		JBrowse link
G Apob apolipoprotein B ISO protein:increased expression:serum RGD PMID:2352345 RGD:2313973 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoe apolipoprotein E susceptibility ISO DNA:polymorphism: :3932T>C (human) RGD PMID:17016617 RGD:1601237 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase susceptibility ISO DNA:SNPs,haplotypes:multiple RGD PMID:20458436 RGD:401794454 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO associated with diabetes mellitus;mRNA:protein:increased expression:blood mononuclear cell: RGD PMID:26717922 RGD:14398486 NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770 		JBrowse link
G Cbs cystathionine beta synthase susceptibility ISO DNA:SNPs,haplotypes:multiple RGD PMID:20458436 RGD:401794454 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:29111308 RGD:155260331 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 treatment ISO RGD PMID:29111308 RGD:155260331 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 ISO RGD PMID:23602964 RGD:8552262 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd36 CD36 molecule ISO associated with Hyperlipidemias RGD PMID:22718544 RGD:6893487 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Ephx2 epoxide hydrolase 2 IDA RGD PMID:16306811 RGD:1580986 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G F2 coagulation factor II, thrombin susceptibility ISO ClinVar Annotator: match by term: Ischemic stroke | ClinVar Annotator: match by term: Ischemic stroke, susceptibility to ClinVar
OMIM		 PMID:2222810 PMID:2429850 PMID:2825773 PMID:6305407 PMID:8696333 More... NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F5 coagulation factor V susceptibility ISO ClinVar Annotator: match by term: Ischemic stroke, susceptibility to ClinVar
OMIM		 PMID:7586244 PMID:7803250 PMID:7877648 PMID:7910348 PMID:7911872 More... NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G F7 coagulation factor VII treatment ISO protein:increased expression, increased activity:plasma (human)
human protein in a mouse model		 RGD PMID:14733777 PMID:21998055 RGD:11049518, RGD:11049520 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Fbn1 fibrillin 1 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:7611299 PMID:8894692 PMID:9401003 PMID:9536098 PMID:10533071 More... NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889 		JBrowse link
G Folh1 folate hydrolase 1 susceptibility ISO DNA:SNPs,haplotypes:multiple RGD PMID:20458436 RGD:401794454 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
G Gch1 GTP cyclohydrolase 1 exacerbates
treatment		 ISO
IMP		 DNA:SNP:3' UTR:+243C>T (human)
DNA:SNP, haplotype:rs841 (human)		 RGD PMID:21181356 PMID:16282548 PMID:21963893 RGD:329961322, RGD:329961574, RGD:329961572 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gp6 glycoprotein VI ameliorates ISO RGD PMID:34237320 RGD:401794450 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Gpx3 glutathione peroxidase 3 susceptibility ISO DNA, protein:SNP,decreased expression:promoter,plasma:-861A>T (human)
DNA:SNPs, haplotypes:promoter:rs8177412, rs870407, rs870406 (human)
DNA:SNPs, haplotype:promoter:-942 A>C, -927 T>C, -861 A>T, -302 A>T, -284 T>A, -568 T>C, -518 T>C, -65 T>C (human)		 RGD PMID:25126700 PMID:20946167 PMID:17122425 RGD:401827128, RGD:401827165, RGD:401827163 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 severity ISO RGD PMID:23723305 RGD:13792693 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grn granulin precursor ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:18723524 PMID:28492532 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Gsn gelsolin severity ISO protein:decreased expression:blood plasma (human) RGD PMID:21481565 RGD:329337334 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G H19 H19 imprinted maternally expressed transcript disease_progression
susceptibility
ameliorates		 ISO RNA:increased expression:blood plasma, plasma exosome (human)
DNA:SNP::(rs217727) (human)
DNA:SNPs,haplotypes: (rs217727,rs4929984) (human)
associated with atherosclerosis		 RGD PMID:36453417 PMID:33541284 PMID:28203482 PMID:30778327 PMID:36453417 RGD:155882574, RGD:156430336, RGD:155900760, RGD:155900761, RGD:155882574 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:1634355 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha severity ISO protein:increased expression:blood serum (human) RGD PMID:34708885 RGD:155260326 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:plasma RGD PMID:23288172 RGD:8696004 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:23311871 RGD:10755574 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf1a HNF1 homeobox A susceptibility ISO DNA:SNPs,haplotypes:multiple RGD PMID:28035729 RGD:329901837 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:20083630 RGD:8547724 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifnb1 interferon beta 1 susceptibility
no_association		 ISO
IDA		 DNA:SNP,haplotype: rs9333358(human) RGD PMID:31810024 PMID:16514094 RGD:401851921, RGD:401854228 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il10 interleukin 10 treatment ISO RGD PMID:29111308 RGD:155260331 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 treatment IEP RGD PMID:20584315 RGD:8655991 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:29111308 RGD:155260331 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:29111308 RGD:155260331 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf8 interferon regulatory factor 8 exacerbates ISO RGD PMID:24528256 RGD:329902074 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Itga9 integrin subunit alpha 9 susceptibility ISO DNA:SNPs,haplotype:rs189897,rs2212020(human) RGD PMID:21764681 RGD:13602007 NCBI chr 8:118,307,424...118,615,527
Ensembl chr 8:118,307,381...118,613,754 		JBrowse link
G Itgam integrin subunit alpha M ISO protein:increased expression:neutrophil (human) RGD PMID:31355307 RGD:329901831 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Kalrn kalirin, RhoGEF kinase susceptibility
sexual_dimorphism		 ISO DNA:SNP:intron: (rs6438833) (human)
DNA:SNPs, haplotypes:intron,cds: (rs7620580, rs1708303) (human)		 RGD PMID:25917671 PMID:28706949 RGD:11085239, RGD:329956420 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO RGD PMID:29037241 RGD:329969881 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Lipg lipase G, endothelial type susceptibility ISO DNA:polymorphism: :584C>T (human) RGD PMID:17016617 RGD:1601237 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260 		JBrowse link
G Lta lymphotoxin alpha ISO RGD PMID:14593215 RGD:1580416 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Map2 microtubule-associated protein 2 IDA RGD PMID:22444278 RGD:6483079 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:23968852 RGD:10412642 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mir145 microRNA 145 ameliorates ISO miRNA:increased expression:blood (human) RGD PMID:22370881 PMID:26722607 RGD:155260291, RGD:155260295 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:brain RGD PMID:20840605 RGD:41410884 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir210 microRNA 210 severity
treatment		 ISO miRNA:decreased expression:blood (human)
miRNA:decreased expression:blood serum (human)		 RGD PMID:21622133 PMID:29111308 PMID:34708885 RGD:155260318, RGD:155260331, RGD:155260326 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir223 microRNA 223 treatment IEP RGD PMID:28469772 RGD:35668865 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir30a microRNA 30a treatment IEP RGD PMID:28469772 RGD:35668865 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir383 microRNA 383 treatment IEP RGD PMID:28469772 RGD:35668865 NCBI chr16:54,040,340...54,040,413
Ensembl chr16:54,040,340...54,040,413 		JBrowse link
G Mir494 microRNA 494 disease_progression ISO RGD PMID:32239566 RGD:155883173 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16846501 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16846501 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:transition:cds:g.677C>T (human) RGD PMID:10929044 RGD:1580590 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility ISO DNA:SNPs,haplotypes:multiple RGD PMID:20458436 RGD:401794454 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Myrf myelin regulatory factor ISO DNA:SNP:exon:rs174535(human) RGD PMID:36193932 RGD:213230151 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 IEP protein:increased expression:brain, neuron, astrocyte: RGD PMID:17523870 RGD:401854233 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 More... NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch3 notch receptor 3 ISO ClinVar Annotator: match by term: Ischemic stroke ClinVar PMID:9388399 PMID:10371548 PMID:10802804 PMID:10854111 PMID:11102981 More... NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Npy neuropeptide Y IEP
ISO		 protein:increased expression:cerebral cortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11821007 PMID:17123484 RGD:10448931 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 susceptibility ISO DNA:SNPs, haplotype:promoter:c.-115G>A, c.-840C>A (rs12221497, rs61896015) (human) RGD PMID:21903943 RGD:401842365 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Park7 Parkinsonism associated deglycase treatment ISO RGD PMID:18003894 PMID:18003894 RGD:13462069, RGD:13462069 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO associated with Metabolic Syndrome; DNA:duplication:5' utr:-108 3G>4G (human) RGD PMID:18506375 RGD:2311309 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 ISO DNA:SNP:intron: (rs12526453) (human) RGD PMID:23042660 RGD:401900685 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831 		JBrowse link
G Pla2g7 phospholipase A2 group VII ISO RGD PMID:18201705 RGD:6482775 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:1579960 PMID:1899364 PMID:9183334 PMID:16148626 PMID:18195371 More... NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:12133459 PMID:16773802 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:20138161 RGD:6483804 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pon1 paraoxonase 1 susceptibility ISO DNA:missense mutation:cds:p.Q192R (human) RGD PMID:10729395 RGD:1580196 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pon2 paraoxonase 2 susceptibility ISO DNA:SNPs,haplotypes: (rs11545941, rs6954345) (human) RGD PMID:20458436 RGD:401794454 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248 		JBrowse link
G Prkch protein kinase C, eta susceptibility ISO ClinVar Annotator: match by term: Cerebral infarction, susceptibility to | ClinVar Annotator: match by term: Ischemic stroke ClinVar
OMIM		 PMID:12958323 PMID:17206144 PMID:25741868 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:33761690 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Pros1 protein S ISO DNA:missense mutation:exon:p.R355C (1063C>T) (human) RGD PMID:21172841 RGD:11250416 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286 		JBrowse link
G Ptgis prostaglandin I2 synthase exacerbates
treatment		 ISO
IMP		 DNA:SNP, haplotype:3' utr: (rs5602) (human)
DNA:SNPs:exon, 3' utr: (rs5629, rs5602) (human)
DNA:repeat:promoter:g.-6(CCGCCAGCC)3-7 (human)		 RGD PMID:28478978 PMID:28108096 PMID:11130769 PMID:11997284 RGD:401901149, RGD:401959400, RGD:401901269, RGD:401901194 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Rbp4 retinol binding protein 4 exacerbates
severity		 ISO protein:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)
associated with diabetes mellitus; protein:increased expression:blood serum (human)		 RGD PMID:19846170 PMID:30030781 PMID:30038059 RGD:329845582, RGD:329853305, RGD:329845588 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 susceptibility ISO DNA:polymorphism::HLA-A31:01 (human) RGD PMID:24767290 RGD:401827096 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 susceptibility ISO DNA:polymorphism,haplotype::HLA-B37:01 (human) RGD PMID:24767290 RGD:401827096 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:25702149 RGD:11075081 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO associated with Venous Thrombosis RGD PMID:10446335 RGD:8661653 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 IEP mRNA:increased expression:cerebral cortex, neuron RGD PMID:15349978 RGD:1643205 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO mRNA:increased expression:blood (human) RGD PMID:35041140 RGD:155598600 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Tbxas1 thromboxane A synthase 1 susceptibility ISO DNA:polymorphisms: : RGD PMID:19403042 RGD:11059536 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096 		JBrowse link
G Thbd thrombomodulin susceptibility ISO DNA:missense mutation:cds:p.A455V (human) RGD PMID:15574195 RGD:5685021 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:16173529 PMID:29111308 RGD:1580315, RGD:155260331 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B disease_progression ISO RGD PMID:19895657 RGD:7205492 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 ISO DNA:SNP: :rs2075650 (human) RGD PMID:26171154 RGD:13464126 NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915 		JBrowse link
G Tyms thymidylate synthetase susceptibility ISO DNA:SNPs,haplotypes: (rs502396,rs16430,rs8423) RGD PMID:20458436 RGD:401794454 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Vim vimentin IEP RGD PMID:18802758 RGD:6480442 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Chronic Cerebral Hypoperfusion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 IEP protein:decreased expression:hippocampus RGD PMID:22639386 RGD:11541085 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Apoe apolipoprotein E IEP protein:increased expression:cerebral cortex, synapse RGD PMID:28620701 RGD:13703133 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein IEP protein:increased expression:cerebral white matter: RGD PMID:11743996 RGD:10054250 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bace1 beta-secretase 1 IEP protein:increased expression:hippocampus RGD PMID:28683457 RGD:13782142 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like IEP mRNA:increased expression:hippocampus RGD PMID:24072673 RGD:10402542 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Dag1 dystroglycan 1 IEP RGD PMID:21192954 RGD:11541061 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Fth1 ferritin heavy chain 1 IEP protein:increased expression:hippocampus RGD PMID:22639386 RGD:11541085 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 treatment IDA RGD PMID:16645134 RGD:10401930 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP RGD PMID:24838625 RGD:9686415 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 IEP RGD PMID:24838625 RGD:9686415 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:hippocampus RGD PMID:24072673 RGD:10402542 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO protein:hyperphosphorylation:brain: RGD PMID:24371084 RGD:10412307 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO protein:hyperphosphorylation:corpus callosum, endothelial cell, astrocyte: RGD PMID:24371084 RGD:10412307 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 IEP protein:increased expression:dentate gyrus RGD PMID:17931356 RGD:10412049 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Nos3 nitric oxide synthase 3 IMP RGD PMID:15703700 RGD:13824977 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox1 NADPH oxidase 1 ameliorates IMP RGD PMID:24294978 RGD:329955573 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Tfrc transferrin receptor IEP protein:increased expression:hippocampus RGD PMID:22639386 RGD:11541085 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
lateral medullary syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fshb follicle stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17344003 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
middle cerebral artery infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:23149556 PMID:24602692 RGD:12790979, RGD:12791996 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Ace angiotensin I converting enzyme treatment IMP RGD PMID:24471927 RGD:11039026 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 IEP mRNA, protein:increased expression:brain RGD PMID:24090950 RGD:9685436 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acvr1 activin A receptor type 1 ISO RGD PMID:33345977 RGD:329845521 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Acvr2b activin A receptor type 2B ISO mRNA:increased expression:brain (mouse) RGD PMID:33763412 RGD:329849104 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23437309 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP
ISO		 associated with Diabetes Mellitus, Experimental
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25446913 PMID:24211797 RGD:8696008 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen IEP protein:increased expression:brain, serum RGD PMID:24090950 RGD:9685436 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP protein:altered localization: : RGD PMID:15181376 RGD:10047403 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ak1 adenylate kinase 1 IEP protein:decreased expression:cerebral cortex (rat) RGD PMID:16468349 RGD:5508760 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Alb albumin treatment ISO RGD PMID:22227456 RGD:11036100 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19309543 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 IEP protein:increased degradation:brain RGD PMID:19240038 RGD:13461853 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment IEP RGD PMID:24012531 RGD:13703113 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apoe apolipoprotein E IDA RGD PMID:19623195 RGD:6903926 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein treatment IEP RGD PMID:28963051 RGD:13782054 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp4 aquaporin 4 treatment IEP
IMP		 RGD PMID:20815926 PMID:33127515 RGD:8695955, RGD:155646130 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein IEP RGD PMID:22645329 RGD:10395314 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Atf3 activating transcription factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:22200499 PMID:21891976 RGD:10053665, RGD:10053704 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23143152 RGD:10054501 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcan brevican IEP RGD PMID:15869933 RGD:9590118 NCBI chr 2:173,454,479...173,467,717
Ensembl chr 2:173,454,482...173,467,460 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:23143152 RGD:10054501 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP RGD PMID:20417695 PMID:35218623 RGD:4891138, RGD:401960864 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 treatment IMP RGD PMID:22108007 RGD:11561900 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP protein:increased expression:brain RGD PMID:17379825 RGD:9685412 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like IEP RGD PMID:15902200 PMID:21029239 RGD:2314138, RGD:9068917 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G C1qtnf6 C1q and TNF related 6 ameliorates IEP RGD PMID:35322553 RGD:242905190 NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412 		JBrowse link
G C3 complement C3 IEP
ISO		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23199288 PMID:22103620 RGD:7175514 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Calca calcitonin-related polypeptide alpha treatment IEP RGD PMID:30531687 RGD:329849008 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha IEP RGD PMID:14688616 RGD:1358416 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Casp3 caspase 3 treatment IDA
IEP		 RGD PMID:21891976 PMID:26868427 PMID:23143152 RGD:10053704, RGD:13782346, RGD:10054501 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 IEP RGD PMID:26868427 RGD:13782346 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:26868427 RGD:13782346 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12374626 PMID:23043544 PMID:25257527 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Cd36 CD36 molecule treatment ISO RGD PMID:25216018 RGD:11041113 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd86 CD86 molecule IEP protein:increased expression:brain subventricular zone, microglial cell (rat) RGD PMID:19053043 RGD:2313025 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO RGD PMID:24920629 RGD:13782375 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cldn5 claudin 5 treatment IEP RGD PMID:24842554 RGD:13204729 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IDA RGD PMID:35218623 RGD:401960864 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone IEP protein:decreased expression:median eminence of hypothalamus (rat) RGD PMID:21741032 RGD:5490538 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crp C-reactive protein ISO RGD PMID:15545914 RGD:9585995 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 treatment IEP RGD PMID:20417695 RGD:4891138 NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO
IEP		 mRNA, protein:increased expression:brain: RGD PMID:19298757 PMID:15530654 RGD:11039420, RGD:11039425 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO RGD PMID:10825390 RGD:632989 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IEP mRNA:increased expression:cerebral cortex RGD PMID:10825390 RGD:632989 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP RGD PMID:23002367 RGD:14700877 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Dicer1 dicer 1 ribonuclease III IEP mRNA:decreased expression:brain: RGD PMID:26294080 RGD:11553310 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:11726790 RGD:9588643 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha IMP RGD PMID:23516428 RGD:9589049 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 IEP RGD PMID:9522364 RGD:13208524 NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17197033 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Egr1 early growth response 1 IEP RGD PMID:22645329 RGD:10395314 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 IEP RGD PMID:22645329 RGD:10395314 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr4 early growth response 4 IEP RGD PMID:22645329 RGD:10395314 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha treatment IDA
IMP		 RGD PMID:23669639 PMID:19763736 RGD:10395346, RGD:10755569 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:10700596 RGD:10450546 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Eng endoglin ISO RGD PMID:24876084 RGD:11041171 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Epcam epithelial cell adhesion molecule IEP RGD PMID:15950761 RGD:11038820 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephb2 Eph receptor B2 treatment IEP
ISO		 mRNA,protein:increased expression: cortex, cerebral cortex subventricular zone RGD PMID:16321245 PMID:16321245 RGD:1642069, RGD:1642069 NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059 		JBrowse link
G Epn1 Epsin 1 IEP protein:increased degradation:brain RGD PMID:19240038 RGD:13461853 NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:20833153 PMID:20547143 RGD:10400898, RGD:10401066 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IEP RGD PMID:9974119 RGD:10401103 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G F11 coagulation factor XI ISO RGD PMID:16533887 RGD:11041786 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F12 coagulation factor XII treatment ISO RGD PMID:16533887 PMID:16533887 RGD:11041786, RGD:11041786 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:29651748 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fadd Fas associated via death domain treatment ISO
IEP		 RGD PMID:18950622 PMID:23378241 RGD:11341807, RGD:11344885 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fgf2 fibroblast growth factor 2 treatment IEP RGD PMID:30531687 RGD:329849008 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf21 fibroblast growth factor 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769 		JBrowse link
G Gap43 growth associated protein 43 treatment IEP RGD PMID:30531687 RGD:329849008 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase IDA RGD PMID:25882840 RGD:13792686 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment IEP RGD PMID:24956890 RGD:401717568 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment IMP RGD PMID:29497380 RGD:40925919 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide treatment IDA RGD PMID:19352052 RGD:9850083 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:19352052 RGD:9850083 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Glul glutamate-ammonia ligase treatment IEP protein:increased expression:eye
protein:increased expression:cerebrum, astrocyte		 RGD PMID:24518488 PMID:23595285 PMID:26024074 PMID:26093193 RGD:401794420, RGD:401794586, RGD:401794592, RGD:401794587 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 treatment IEP RGD PMID:26674869 RGD:11068571 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grn granulin precursor treatment ISO RGD PMID:23972823 RGD:10401661 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial IEP mRNA:increased expression:cerebral cortex RGD PMID:12505684 RGD:632868 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA RGD PMID:28440874 RGD:13792734 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin ameliorates ISO RGD PMID:18234195 PMID:9927495 RGD:329333031, RGD:329333033 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates IEP
ISO
IMP		 RNA:increased expression:brain (rat)
RNA:increased expression:brain (mouse)		 RGD PMID:28203482 PMID:28630232 PMID:35322553 PMID:31170091 PMID:32335212 RGD:155900760, RGD:242905192, RGD:242905190, RGD:242905188, RGD:156451661 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA, protein:increased expression:cerebral cortex, hippocampus, corpus striatum RGD PMID:21957487 RGD:11041635 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Has2 hyaluronan synthase 2 IEP mRNA:increased expression:brain RGD PMID:11283406 RGD:9588631 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hdac2 histone deacetylase 2 exacerbates ISO RGD PMID:32239566 RGD:155883173 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hdac4 histone deacetylase 4 treatment IEP mRNA,protein:decreased expression:brain: RGD PMID:23480850 RGD:9681449 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac5 histone deacetylase 5 treatment IEP mRNA,protein:decreased expression:brain: RGD PMID:23480850 RGD:9681449 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Hdac9 histone deacetylase 9 IEP mRNA:increased expression:brain: RGD PMID:23480850 RGD:9681449 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IDA RGD PMID:21029239 RGD:9068917 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:23480850 RGD:9681449 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP
IDA
ISO		 RGD PMID:24252362 PMID:23870531 PMID:20888632 RGD:10755587, RGD:10755755, RGD:10755588 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hp haptoglobin IEP RGD PMID:22103620 RGD:7175514 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IMP
ISO		 rat gene in mouse model RGD PMID:17473852 PMID:21709150 RGD:5688754, RGD:6218961 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htra2 HtrA serine peptidase 2 IEP
ISO		 protein:increased expression:brain, cytosol (rat)
protein:increased expression:brain, cytosol (mouse)		 RGD PMID:16978742 PMID:15306124 RGD:2314385, RGD:5688372 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 IMP RGD PMID:31250553 RGD:14985213 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141 		JBrowse link
G Hvcn1em2Mcwi hydrogen voltage-gated channel 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:31250553 RGD:14985213
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:16286924 RGD:10045955 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 ameliorates ISO RGD PMID:28630232 RGD:242905192 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il13 interleukin 13 IEP protein:increased expression:cerebral cortex RGD PMID:23028794 RGD:7204480 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il1b interleukin 1 beta ameliorates
treatment		 IEP
ISO		 protein:increased expression:cerebral cortex (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25257527 PMID:23028794 PMID:35322553 PMID:29498696 PMID:24916922 RGD:7204480, RGD:242905190, RGD:13792833, RGD:10450594 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human gene in a rat model RGD PMID:7790404 RGD:8551708 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il22 interleukin 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Il4 interleukin 4 IEP protein:increased expression:cerebral cortex RGD PMID:23028794 RGD:7204480 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 IEP RGD PMID:23028794 RGD:7204480 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12374626 PMID:21940958 PMID:25257527 PMID:29498696 RGD:13792833 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Il7r interleukin 7 receptor IEP protein:increased expression:brain: RGD PMID:30676545 RGD:151347693 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha ISO RGD PMID:29967576 RGD:27226878 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330 		JBrowse link
G Inhba inhibin subunit beta A ISO RGD PMID:33345977 RGD:329845521 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Irf4 interferon regulatory factor 4 IEP RGD PMID:25652434 RGD:11530061 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO
IMP		 RGD PMID:26661208 PMID:25477223 PMID:21750563 RGD:329955572, RGD:401700383, RGD:329955444 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Mag myelin-associated glycoprotein treatment IMP RGD PMID:15678116 RGD:9685232 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:27152455 PMID:35218623 RGD:13800881, RGD:401960864 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA RGD PMID:27152455 PMID:35218623 RGD:13800881, RGD:401960864 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapt microtubule-associated protein tau treatment IEP
IDA
ISO		 RGD PMID:28886009 PMID:25903928 PMID:28886009 RGD:13800886, RGD:13800913, RGD:13800886 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mir107 microRNA 107 IEP RNA:increased expression:brain RGD PMID:26294080 RGD:11553310 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853 		JBrowse link
G Mir132 microRNA 132 treatment ISO mRNA:decreased expression:brain (mouse) RGD PMID:33763412 PMID:33763412 RGD:329849104, RGD:329849104 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir140 microRNA 140 ameliorates ISO
IEP		 miRNA:decreased expression:cerebral cortex (rat) RGD PMID:33246036 PMID:27035554 RGD:329337375, RGD:329337377 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir19a microRNA 19a ISO RNA:decreased expression:brain (mouse) RGD PMID:32335212 RGD:156451661 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir210 microRNA 210 treatment IEP RGD PMID:34337881 RGD:155269103 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir29b1 microRNA 29b-1 exacerbates IMP RGD PMID:35322553 RGD:242905190 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir494 microRNA 494 ameliorates ISO RGD PMID:32239566 PMID:31465536 RGD:155883173, RGD:156430320 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19309543 PMID:24842554 RGD:13204729 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mt3 metallothionein 3 IEP protein:decreased expression:brain RGD PMID:8869568 RGD:9685807 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IEP
IDA		 RGD PMID:24583056 PMID:21185267 PMID:23777415 RGD:10040971, RGD:10041016, RGD:10040974 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 IEP RGD PMID:21386696 RGD:13801046 NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase treatment IMP RGD PMID:28495827 RGD:13781880 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 treatment ISO
IMP		 RGD PMID:32962079 PMID:29497380 RGD:40924633, RGD:40925919 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Nefh neurofilament heavy chain ISO RGD PMID:29967576 RGD:27226878 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nefl neurofilament light chain ISO protein:increased expression:brain RGD PMID:29967576 RGD:27226878 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nefm neurofilament medium chain ISO protein:altered expression:brain RGD PMID:29967576 RGD:27226878 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IDA RGD PMID:23880501 PMID:24466583 RGD:10412696, RGD:10412714 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:21122797 RGD:10413868 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor treatment ISO
IMP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:10408807 PMID:29409115 RGD:402463967 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor treatment IDA RGD PMID:22678884 RGD:10413900 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 treatment IEP RGD PMID:24842554 RGD:13204729 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO		 protein:increased expression:brain (rat)
mRNA:increased expression:brain (mouse)		 RGD PMID:21959178 PMID:22020035 RGD:5508751, RGD:5509037 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox1 NADPH oxidase 1 treatment IEP RGD PMID:30816157 RGD:329955567 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP protein:increased expression:brain RGD PMID:21120604 PMID:25069640 RGD:5133239, RGD:11035212 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrg1 neuregulin 1 treatment
ameliorates		 ISO RGD PMID:20691195 PMID:30206770 RGD:10449015, RGD:405650589 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase treatment IEP associated with Hypertension RGD PMID:17920569 RGD:8657395 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Park7 Parkinsonism associated deglycase treatment ISO RGD PMID:17882163 RGD:13463450 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment ISO
IDA
IEP		 RGD PMID:21311064 PMID:25882840 PMID:23143152 PMID:23801245 RGD:5683909, RGD:13792686, RGD:10054501, RGD:11073732 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pawr pro-apoptotic WT1 regulator treatment ISO
IEP		 protein:increased expression:brain: RGD PMID:16403464 PMID:19352052 PMID:11323519 RGD:9835380, RGD:9850083, RGD:9835381 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha treatment IDA RGD PMID:16917016 RGD:11084934 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta treatment IDA RGD PMID:16917016 RGD:11084934 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Plat plasminogen activator, tissue type IEP
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12297567 PMID:17690543 PMID:18453163 PMID:20547619 PMID:29651748 More... RGD:1580876 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: therapeutic CTD PMID:11677890 PMID:15181847 PMID:17702958 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pld1 phospholipase D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Prkcg protein kinase C, gamma ISO RGD PMID:14688616 RGD:1358416 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:24159062 RGD:11100027 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 IEP mRNA:increased expression:cerebral cortex RGD PMID:15869933 RGD:9590118 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 treatment IEP RGD PMID:30531687 RGD:329849008 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935 		JBrowse link
G Reln reelin severity ISO RGD PMID:16438965 RGD:13207538 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a treatment IEP
IMP		 RGD PMID:21840379 PMID:23275173 RGD:9850121, RGD:9850122 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Rpl28 ribosomal protein L28 IEP RGD PMID:16805800 RGD:6480229 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032 		JBrowse link
G Runx1 RUNX family transcription factor 1 IAGP mRNA:increased expression:brain RGD PMID:24672479 RGD:11251714 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G S100a5 S100 calcium binding protein A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25257527 NCBI chr 2:176,095,332...176,099,546
Ensembl chr 2:176,097,539...176,099,546 		JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:cerebrum, astrocyte RGD PMID:23595285 RGD:401794586 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Serpine1 serpin family E member 1 IEP RGD PMID:14512838 RGD:1580876 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf1 serpin family F member 1 treatment IDA RGD PMID:22714093 RGD:8655545 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Serpinh1 serpin family H member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Shh sonic hedgehog signaling molecule treatment ISO RGD PMID:22324418 RGD:12879461 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sirt1 sirtuin 1 treatment IMP
ISO		 RGD PMID:23600725 PMID:23600725 RGD:9585664, RGD:9585664 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 treatment IMP
ISO		 protein:increased expression:brain: RGD PMID:12535773 PMID:27798271 RGD:1580583, RGD:14398833 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 treatment IEP RGD PMID:20423712 RGD:401794585 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 treatment IEP RGD PMID:9419067 RGD:12879855 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 treatment IMP RGD PMID:31250553 RGD:14985213 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor treatment IEP RGD PMID:14500739 RGD:9999390 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Smo smoothened, frizzled class receptor treatment IMP RGD PMID:23696546 PMID:23499832 RGD:12832759, RGD:12879404 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Smox spermine oxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:30576531 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710 		JBrowse link
G Snap91 synaptosome associated protein 91 IEP protein:increased degradation:brain RGD PMID:19240038 RGD:13461853 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367 		JBrowse link
G Sod1 superoxide dismutase 1 treatment IDA
IEP		 mRNA, protein:increased expression:cerebral cortex (rat) RGD PMID:22001340 PMID:22133807 RGD:8657021, RGD:8657023 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sphk2 sphingosine kinase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:23043544 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ameliorates IEP
ISO		 RGD PMID:31409163 PMID:28630232 RGD:14995477, RGD:242905192 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase IEP protein:decreased expression:substantia nigra pars compacta, neuron (rat) RGD PMID:21366664 RGD:5128609 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor treatment
ameliorates		 IEP
ISO
IMP		 RGD PMID:24916922 PMID:28630232 PMID:35322553 PMID:15647744 PMID:29498696 RGD:10450594, RGD:242905192, RGD:242905190, RGD:13825261, RGD:13792833 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IMP RGD PMID:15647744 RGD:13825261 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates IDA RGD PMID:32736673 RGD:127284860 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Upp1 uridine phosphorylase 1 IEP mRNA, protein:increased expression:brain (rat) RGD PMID:18457515 RGD:2317094 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment IMP
IEP		 mRNA,protein:increased expression:cerebral cortex (rat) RGD PMID:29497380 PMID:30531687 PMID:27035554 RGD:40925919, RGD:329849008, RGD:329337377 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12374626 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Multi-Infarct Dementia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO protein:decreased expression:cerebrospinal fluid: RGD PMID:1677459 RGD:10054257 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:18938189 RGD:10054050 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18938189 RGD:10054050 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:21279683 RGD:10449132 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Il2 interleukin 2 severity ISO protein:increased secretion:mononuclear cell: RGD PMID:8586980 RGD:10047081 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
pyridoxamine 5'-phosphate oxidase deficiency term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpo pyridoxamine 5'-phosphate oxidase ISO ClinVar Annotator: match by term: Pyridoxal phosphate-responsive seizures
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:9536098 PMID:15182361 PMID:15772097 PMID:16199547 PMID:17216302 More... NCBI chr10:81,924,584...81,930,844
Ensembl chr10:81,924,569...81,930,871 		JBrowse link
transient cerebral ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 IEP RGD PMID:15781474 RGD:1579751 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP mRNA, protein:increased expression:brain RGD PMID:16630594 RGD:9681747 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 IEP RGD PMID:16630594 RGD:9681747 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 IMP RGD PMID:16504947 RGD:10755337 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23437309 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP
ISO		 protein:altered expression:cerebral cortex, striatum (rat)
protein:increased expression:brain, plasma		 RGD PMID:22528836 PMID:23288172 RGD:7245542, RGD:8696004 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen IEP RGD PMID:21934531 RGD:8549480 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor treatment IMP RGD PMID:32913241 RGD:401793747 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO		 mRNA:decreased expression, altered localization:CA1 pyramidal layer, nucleus:
protein:increased expression:nucleus:		 RGD PMID:14526224 PMID:15087715 RGD:10047409, RGD:10053562 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ang angiogenin treatment IEP RGD PMID:30258350 RGD:155663419 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Ank1 ankyrin 1 IEP RGD PMID:9202331 RGD:1599109 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ank2 ankyrin 2 IEP RGD PMID:9202331 RGD:1599109 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Apoe apolipoprotein E IEP RGD PMID:19623195 RGD:6903926 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Aqp4 aquaporin 4 treatment IEP RGD PMID:24773551 RGD:13207320 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Atf2 activating transcription factor 2 IDA
IEP		 RGD PMID:10077326 PMID:9813301 RGD:10047405, RGD:10047413 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta IEP protein:increased expression:cerebrum (rat) RGD PMID:21950801 RGD:13792582 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Axin2 axin 2 treatment IEP RGD PMID:31650542 RGD:151356749 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bace1 beta-secretase 1 IEP protein:increased activity,increased expression:brain cortex RGD PMID:15120577 RGD:13782170 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bad BCL2-associated agonist of cell death ISO CTD Direct Evidence: marker/mechanism CTD PMID:12629175 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21167243 RGD:10054102 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 IEP protein:increased expression:hippocampus CA1, pyramidal cell RGD PMID:12913114 RGD:634629 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA		 protein:decreased expression:brain RGD PMID:18083315 PMID:22509406 PMID:16732092 RGD:2290557, RGD:11561910, RGD:11522725 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l2 Bcl2-like 2 treatment IEP
ISO		 protein:increased expression:cortex and caudate putamen RGD PMID:10724126 PMID:12571640 RGD:14394498, RGD:14394500 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:22509406 RGD:11561910 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bex3 brain expressed X-linked 3 IEP RGD PMID:11124986 RGD:9743974 NCBI chr  X:99,273,270...99,274,799
Ensembl chr  X:99,273,161...99,274,800 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP RGD PMID:14972662 RGD:2314028 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G C3 complement C3 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23199288 PMID:22004711 RGD:7411628 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cab39 calcium binding protein 39 IEP protein:increased expression:brain RGD PMID:27798271 RGD:14398833 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha IEP
ISO		 protein:increased expression:hippocampus RGD PMID:12951199 PMID:12199152 RGD:7241547, RGD:13681927 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Casp3 caspase 3 IDA RGD PMID:21712070 RGD:10053706 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:25872160 RGD:13782285 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 treatment IEP protein:increased expression:cerebral cortex: RGD PMID:30148677 PMID:18096138 RGD:13782286, RGD:4142863 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 IEP
ISO		 associated with Diabetes Mellitus, Experimental;protein:increased expression:neocortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11333366 PMID:15246841 PMID:21712070 RGD:2311321, RGD:10053706 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cav1 caveolin 1 treatment IEP
ISO		 RGD PMID:22007835 PMID:22007835 RGD:8661794, RGD:8661794 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cbl Cbl proto-oncogene treatment IDA RGD PMID:18773943 RGD:4108486 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cbs cystathionine beta synthase treatment ISO XCO:0000348
XCO:0000807		 RGD PMID:22212488 PMID:22212488 RGD:41410880, RGD:41410880 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA
IEP		 mRNA:increased expression:brain (rat) RGD PMID:21487414 PMID:7860708 RGD:8549519, RGD:8549729 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IMP RGD PMID:19428685 RGD:7488896 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccnh cyclin H IEP mRNA, protein:increased expression:hippocampus RGD PMID:10501206 RGD:69371 NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 IEP mRNA:increased expression:brain RGD PMID:19428685 RGD:7488896 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Cd40 CD40 molecule severity ISO RGD PMID:15795333 RGD:11352234 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:15795333 RGD:11352234 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IEP RGD PMID:28254431 RGD:13506925 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO protein:decreased expression:striatum, neuron RGD PMID:11438580 RGD:8552691 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha IEP mRNA, protein:increased expression:hippocampal pyramidal cell layer (rat) RGD PMID:9795105 RGD:10401192 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Chka choline kinase alpha IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:16300643 RGD:10401831 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase severity ISO RGD PMID:20170652 RGD:10402096 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IDA RGD PMID:10077326 RGD:10047405 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12437578 RGD:632385 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:12624302 RGD:10450512 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP protein:decreased expression:hippocampus RGD PMID:24447880 RGD:9491776 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA,protein:decreased expression:hippocampus RGD PMID:24447880 RGD:9491776 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:hippocampus: RGD PMID:24924806 RGD:11352662 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cycs cytochrome c, somatic ISO CTD Direct Evidence: marker/mechanism CTD PMID:11333366 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Daxx death-domain associated protein treatment IDA
IEP		 mRNA,protein:increased expression:cerebral cortex: RGD PMID:17967739 PMID:18096138 RGD:9587802, RGD:4142863 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dbn1 drebrin 1 IEP RGD PMID:8583659 RGD:10398814 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dffb DNA fragmentation factor subunit beta IEP mRNA, protein:increased expression:hippocampus CA1 RGD PMID:11425895 RGD:628524 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 ameliorates
treatment
disease_progression		 ISO
IEP		 RGD PMID:31927543 PMID:30258350 PMID:30653356 RGD:155663354, RGD:155663419, RGD:155663383 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP protein:increased expression:brain RGD PMID:22197701 RGD:7771582 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp16 dual specificity phosphatase 16 IEP protein:increased expression, altered localization:hippocampus, cytosol, nucleus RGD PMID:23280045 RGD:7775014 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Eed embryonic ectoderm development IDA RGD PMID:24007266 RGD:9588303 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha ISO
IEP		 associated with Heart Arrest RGD PMID:11520898 PMID:10541873 RGD:10395353, RGD:11041881 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:19168036 RGD:10450558 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Elk1 ETS transcription factor ELK1 treatment IEP RGD PMID:17091294 RGD:7488902 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEP mRNA:increased expression:brain: RGD PMID:9634555 RGD:9685492 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Ep300 E1A binding protein p300 IEP mRNA:increased expression:cerebrum, ipsilateral side (rat) RGD PMID:22196858 RGD:7349341 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epo erythropoietin treatment IEP
ISO		 RGD PMID:22282883 PMID:24702327 RGD:10401060, RGD:11041699 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO human gene in a rat model RGD PMID:19440222 RGD:2313668 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:10437118 RGD:10401104 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Esr1 estrogen receptor 1 treatment IDA RGD PMID:24548484 PMID:25098259 RGD:10045843, RGD:10045845 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:23593292 RGD:7364962 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F11r F11 receptor treatment IEP RGD PMID:22868201 RGD:7488943 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G F12 coagulation factor XII treatment ISO RGD PMID:16533887 PMID:16533887 RGD:11041786, RGD:11041786 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Fadd Fas associated via death domain IEP mRNA,protein:increased expression:cerebral cortex: RGD PMID:18096138 RGD:4142863 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP
IDA
ISO		 protein:increased expression:brain
protein:increased expression:brain (rat)		 RGD PMID:18410517 PMID:30301943 PMID:18981705 PMID:10972965 RGD:2311437, RGD:153297779, RGD:8686422, RGD:8662928 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP mRNA:increased expression:cerebral cortex: RGD PMID:8858623 RGD:10402044 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 treatment IEP associated with Experimental Diabetes Mellitus RGD PMID:22432030 RGD:155882598 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 treatment ISO RGD PMID:17077813 RGD:10402150 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IEP mRNA, protein:increased expression:striatum (rat) RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase IEP
ISO		 protein:decreased expression:cerebral cortex
mRNA:decreased expression:cerebral cortex
mRNA:decreased expression:heart		 RGD PMID:32426101 PMID:36479246 PMID:34413770 RGD:329901764, RGD:329951019, RGD:329901768 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:22580330 RGD:10449127 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gad1 glutamate decarboxylase 1 disease_progression IEP RGD PMID:20659561 RGD:401900597 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 disease_progression IEP RGD PMID:20659561 RGD:401900597 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase ameliorates ISO DNA:deletion RGD PMID:24004504 RGD:329955375 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gatm glycine amidinotransferase exacerbates ISO DNA:deletion RGD PMID:24004504 RGD:329955375 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment IMP RGD PMID:9920651 RGD:329961573 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA,protein:decreased expression:brain: RGD PMID:17560544 RGD:12907500 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gja1 gap junction protein, alpha 1 treatment ISO
IEP		 protein:increased expression:brain RGD PMID:22812228 PMID:23328809 RGD:7207263, RGD:8662426 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjb6 gap junction protein, beta 6 IEP protein:increased expression:hippocampus: RGD PMID:21718970 RGD:6480433 NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Glrx glutaredoxin IEP mRNA,protein:decreased expression:brain: RGD PMID:10329397 RGD:9686043 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Glul glutamate-ammonia ligase treatment IEP associated with carotid artery occlusion
protein:increased expression:hippocampus		 RGD PMID:27664163 PMID:25365917 PMID:21272618 PMID:21371894 RGD:401794415, RGD:401794591, RGD:401794590, RGD:401794419 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 treatment ISO
IDA		 human protein in a rat model RGD PMID:24407245 PMID:21361730 PMID:20145654 RGD:13504852, RGD:13504855, RGD:13504854 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gp6 glycoprotein VI ameliorates ISO RGD PMID:34237320 RGD:401794450 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO RGD PMID:30098076 RGD:401827833 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ameliorates
treatment		 IMP
IDA
ISO		 associated with hyperhomocysteinemia RGD PMID:30885791 PMID:12932824 PMID:30885791 RGD:401940141, RGD:401950480, RGD:401940141 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ameliorates IMP RGD PMID:30885791 RGD:401940141 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IDA RGD PMID:15525350 RGD:10401855 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:20830300 RGD:8693742 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 treatment IEP RGD PMID:24771108 RGD:9686115 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP protein:increased expression:cerebral cortex, caudoputamen (rat) RGD PMID:20417628 PMID:30258350 RGD:9068877, RGD:155663419 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:brain, plasma RGD PMID:23288172 RGD:8696004 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP protein:altered expression:cerebral cortex, hippocampus (rat) RGD PMID:20421594 RGD:10041006 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B treatment IDA RGD PMID:22366221 RGD:9999181 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344 		JBrowse link
G Hrh2 histamine receptor H 2 IEP protein:decreased expression:caudate putamen (rat) RGD PMID:16181737 RGD:9685533 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hsf1 heat shock transcription factor 1 treatment IEP
IDA		 protein:increased expression:brain, nucleus (rat)
associated with Heart Arrest		 RGD PMID:26070787 PMID:23528677 RGD:10402389, RGD:10402772 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:25632565 RGD:11354959 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP protein:increased expression:brain, postsynaptic density (rat) RGD PMID:9425004 RGD:10059344 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP protein:increased expression:brain,astrocyte: RGD PMID:10559386 RGD:10402577 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Htra2 HtrA serine peptidase 2 treatment IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15306124 PMID:19462455 RGD:10402932 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Htt huntingtin IEP protein:increased degradation:brain RGD PMID:12957494 RGD:1304431 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22379785 RGD:8547729 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifnb1 interferon beta 1 ameliorates IDA RGD PMID:12973019 RGD:401851924 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Igf1 insulin-like growth factor 1 severity IEP protein:decreased expression:serum (rat) RGD PMID:25098324 RGD:12904924 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IEP RGD PMID:24261295 RGD:7495766 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:24053818 RGD:7364868 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta IDA
ISO		 RGD PMID:23147509 PMID:22284622 RGD:7175551, RGD:7175554 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IDA
ISO		 human protein in a rat model RGD PMID:15837124 PMID:20412072 RGD:1626674, RGD:8551852 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Ilk integrin-linked kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15472100 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Itgam integrin subunit alpha M treatment ISO
IEP
IMP		 mRNA:increased expression:cerebral cortex (mouse)
mRNA:increased expression:brain (rat)		 RGD PMID:30123113 PMID:23844255 PMID:22082476 PMID:32407868 PMID:19563786 More... RGD:329853754, RGD:329902067, RGD:329902058, RGD:329901940, RGD:329901933, RGD:329901921, RGD:329901917, RGD:329901916 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb3 integrin subunit beta 3 IEP RGD PMID:18638458 RGD:6907424 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEP mRNA:decreased expression:cerebral cortex (rat) RGD PMID:7500836 RGD:6482813 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jak1 Janus kinase 1 IEP RGD PMID:10756075 RGD:19165138 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 IDA RGD PMID:23764464 RGD:8694326 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP protein:decreased expression:CA1 field of hippocampus, astrocyte, astrocyte projection RGD PMID:20833221 RGD:8662899 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 severity
treatment		 ISO
IDA
IEP		 protein:increased expression:cerebral cortex (rat) RGD PMID:15175651 PMID:24154701 PMID:25062759 RGD:9831121, RGD:9831178, RGD:9831122 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kdm1a lysine demethylase 1A IEP protein:increased expression:cerebral cortex, hippocampus, dentate gyrus (rat) RGD PMID:20542065 RGD:9588301 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO protein:decreased expression:brain (mouse) RGD PMID:21075092 RGD:6893270 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klf5 KLF transcription factor 5 ameliorates IMP RGD PMID:32272873 RGD:45073134 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Kmt2a lysine methyltransferase 2A treatment IMP RGD PMID:34694864 RGD:155888565 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Lcn2 lipocalin 2 IEP protein:increased expression:brain RGD PMID:29122651 PMID:24916903 RGD:126781757, RGD:126790489 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lmna lamin A/C IDA RGD PMID:17683050 RGD:2293745 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 treatment IDA RGD PMID:17173873 RGD:9850154 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 treatment IEP RGD PMID:11720783 RGD:10412057 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349 		JBrowse link
G Madd MAP-kinase activating death domain IEP RGD PMID:12625816 RGD:9588641 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:22509406 RGD:11561910 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA protein:increased threonine phosphorylation:heart, nucleus RGD PMID:9195981 RGD:7495830 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP protein:increased nitrosylation, activity:hippocampus: RGD PMID:23137546 RGD:10412334 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ameliorates ISO RGD PMID:32078472 PMID:32349637 PMID:34628598 PMID:32382778 RGD:155791642, RGD:155804284, RGD:155804283, RGD:155804272 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 treatment IDA RGD PMID:18498770 PMID:18382279 RGD:7495845, RGD:7495847 NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 IEP mRNA:decreased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165 		JBrowse link
G Mbp myelin basic protein IEP mRNA:increased expression:oligodendrocyte: RGD PMID:11460777 RGD:7349336 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2, ER cargo receptor complex subunit IEP mRNA:increased expression:hippocampus RGD PMID:17610559 RGD:11062141 NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841 		JBrowse link
G Mdm2 MDM2 proto-oncogene treatment IDA RGD PMID:24334056 RGD:10412310 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mff mitochondrial fission factor treatment IDA RGD PMID:26116440 RGD:12879457 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039 		JBrowse link
G Mfn2 mitofusin 2 IEP protein:decreased expression:brain (rat) RGD PMID:25147362 RGD:13204807 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir126a microRNA 126a exacerbates ISO RGD PMID:28101763 RGD:401850574 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir155 microRNA 155 treatment IEP RGD PMID:33081480 RGD:151347423 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir195 microRNA 195 severity IMP RGD PMID:32272873 RGD:45073134 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir223 microRNA 223 IMP RGD PMID:31237865 RGD:25824937 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IDA
IEP		 protein:increased activity, increased expression:brain RGD PMID:11592852 PMID:24828425 RGD:8547930, RGD:8657086 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO
IEP
IDA		 protein:increased activity, increased expression:brain RGD PMID:16197500 PMID:24773551 PMID:23046750 PMID:11592852 RGD:8547921, RGD:13207320, RGD:13207323, RGD:8547930 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mt1 metallothionein 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:10884303 RGD:10412650 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A IEP mRNA:increased expression:cerebral cortex RGD PMID:10884303 RGD:10412650 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 IEP mRNA, protein:increased expression:brain RGD PMID:10069533 RGD:9685804 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IEP RGD PMID:30712471 RGD:155791663 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myb MYB proto-oncogene, transcription factor IEP mRNA:increased expression:brain: RGD PMID:24828495 RGD:11532683 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase treatment IMP
ISO		 RGD PMID:28528966 PMID:25603815 RGD:13781879, RGD:13781895 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Ndrg2 NDRG family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23451161 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Ndrg4 NDRG family member 4 ISO RGD PMID:21636852 RGD:7247728 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Nefh neurofilament heavy chain IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nefl neurofilament light chain IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nefm neurofilament medium chain IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755 		JBrowse link
G Nf1 neurofibromin 1 IEP mRNA,protein:increased expression:astrocyte: RGD PMID:8820972 RGD:12789703 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEP protein:increased expression:hippocampal pyramidal neuron, nucleus (rat) RGD PMID:9158652 RGD:10045943 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ngb neuroglobin treatment IEP
ISO
IMP		 associated with Hypertension;mRNA, protein:decreased expression:brain RGD PMID:16647691 PMID:23342777 PMID:12621155 PMID:12621155 RGD:9743952, RGD:9743965, RGD:9743964, RGD:9743964 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830 		JBrowse link
G Ngfr nerve growth factor receptor IEP RGD PMID:11124986 RGD:9743974 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO mRNA, protein:increased expression:brain RGD PMID:20863826 RGD:5508733 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nono non-POU domain containing, octamer-binding ISO protein:altered localization:cerebral cortex (mouse) RGD PMID:29426953 RGD:155883175 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Nos1 nitric oxide synthase 1 IDA protein:increased serine phosphorylation:dentate gyrus RGD PMID:23806217 RGD:7257600 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
IDA		 protein:increased expression:serum (rat) RGD PMID:28944915 PMID:29298658 PMID:29312485 RGD:13450951, RGD:13503353, RGD:13503330 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:30258350 RGD:155663419 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nox1 NADPH oxidase 1 ameliorates IMP RGD PMID:25617620 RGD:329955357 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP protein:increased expression:cerebral cortex (rat)
protein:increased expression:brain (rat)		 RGD PMID:29017857 PMID:28169530 PMID:28552673 RGD:13439718, RGD:13442499, RGD:13439727 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrg1 neuregulin 1 treatment
ameliorates		 ISO RGD PMID:31560696 PMID:30206770 RGD:405649728, RGD:405650589 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrp1 neuropilin 1 IEP mRNA:increased expression:brain RGD PMID:33675584 RGD:401901171 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrxn1 neurexin 1 IEP associated with Hypertension;mRNA:decreased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP protein:increased expression:cerebral cortex RGD PMID:14600440 RGD:8657406 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment ISO
IDA		 protein:altered expression:brain RGD PMID:22345048 PMID:24633199 RGD:7800722, RGD:13208946 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Optn optineurin IEP protein:decreased expression:cerebral cortex (rat) RGD PMID:24235151 RGD:13434905 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Parl presenilin associated, rhomboid-like severity ISO RGD PMID:23921894 RGD:12902620 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment IDA
IEP		 RGD PMID:19840223 PMID:19840223 RGD:2325713, RGD:2325713 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP
ISO		 mRNA:increased expression:brain:
protein:increased expression:cortex,striatum:		 RGD PMID:14705148 PMID:11323519 RGD:1302269, RGD:9835381 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pax6 paired box 6 IEP protein:increased expression:cerebral cortex, striatum, astroglial cell (rat) RGD PMID:24114637 RGD:8552354 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pcna proliferating cell nuclear antigen IEP RGD PMID:9757027 RGD:10448974 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pde4d phosphodiesterase 4D IEP protein:increased expression:hippocampus CA1 RGD PMID:22860212 RGD:7327148 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pdyn prodynorphin IEP mRNA:decreased expression:dentate gyrus, granule cell RGD PMID:8914861 RGD:401851049 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:brain (mouse) RGD PMID:22382321 RGD:6766379 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plat plasminogen activator, tissue type IEP Protein:increased expression, increased activity:hippocampus (rat) RGD PMID:15882815 RGD:1580875 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase IEP
IDA		 protein:increased expression:cerebral cortex (rat) RGD PMID:21375013 PMID:19952306 RGD:7241584, RGD:7241795 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plxnd1 plexin D1 ameliorates IMP RGD PMID:30653356 RGD:155663383 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP
IEP		 RGD PMID:18378216 PMID:19221220 PMID:18973594 RGD:2301892, RGD:8553032, RGD:2301866 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IEP protein:increased expression:cerebral cortex (rat) RGD PMID:15255948 RGD:9999154 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A treatment IDA RGD PMID:21278085 RGD:10043805 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon treatment IEP RGD PMID:30712471 RGD:155791663 NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO protein:decreased expression:cerebral cortex, striatum: RGD PMID:12415119 RGD:10413862 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptafr platelet-activating factor receptor treatment IEP
IMP		 mRNA:decreased expression:cerebral cortex (rat) RGD PMID:17268849 PMID:8158141 RGD:9999221, RGD:10043297 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Pten phosphatase and tensin homolog IEP RGD PMID:12414116 RGD:1358425 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IEP protein:increased expression:hippocampus (rat) RGD PMID:16437207 RGD:10043375 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgis prostaglandin I2 synthase treatment IMP RGD PMID:27834752 RGD:401960086 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptn pleiotrophin IEP mRNA:increased expression:cerebral cortex, vasculature, macrophage (rat) RGD PMID:9570800 RGD:9831440 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 IEP mRNA,protein:increased expression:cerebral cortex: RGD PMID:18096138 RGD:4142863 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 severity
treatment		 IEP
ISO
IDA		 protein:decreased phosphorylation, decreased expression:striatum (rat) RGD PMID:24198371 PMID:24198371 PMID:24198371 RGD:9835010, RGD:9835010, RGD:9835010 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Rack1 receptor for activated C kinase 1 IDA RGD PMID:24007266 RGD:9588303 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Robo1 roundabout guidance receptor 1 disease_progression IEP
ISO		 protein:increased expression:hippocampus
protein:increased expression:brain, astrocyte		 RGD PMID:26764532 PMID:23473743 PMID:27686659 RGD:11573340, RGD:243048431, RGD:243048429 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 IEP protein:increased expression:brain, astrocyte RGD PMID:27686659 RGD:243048429 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Robo4 roundabout guidance receptor 4 IEP protein:increased expression:hippocampus RGD PMID:26764532 RGD:11573340 NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519 		JBrowse link
G Rps6 ribosomal protein S6 IDA RGD PMID:26556340 RGD:11041643 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Sema3e semaphorin 3E disease_progression IEP RGD PMID:30653356 RGD:155663383 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:26851971 RGD:11073692 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO human gene in a rat model RGD PMID:18624913 RGD:8613878 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IEP mRNA:increased expression:hippocampus, pyramidal cell RGD PMID:15046873 RGD:1580967 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sin3a SIN3 transcription regulator family member A IDA RGD PMID:24063527 RGD:9495912 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Sirt6 sirtuin 6 IEP mRNA, protein:decreased expression:brain RGD PMID:23899523 RGD:9586062 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 IEP RGD PMID:27798271 RGD:14398833 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 IEP RGD PMID:23458738 RGD:9999193 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 IEP RGD PMID:23458738 RGD:9999193 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 IEP RGD PMID:23458738 RGD:9999193 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slit2 slit guidance ligand 2 IEP protein:increased expression:hippocampus
protein:increased expression:brain, astrocyte		 RGD PMID:26764532 PMID:27686659 RGD:11573340, RGD:243048429 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IDA RGD PMID:24007266 RGD:9588303 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 treatment IEP RGD PMID:33081480 RGD:151347423 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human protein in a rat model
CTD Direct Evidence: therapeutic
human gene in a rat model		 CTD
RGD		 PMID:12629175 PMID:15829915 PMID:16538228 PMID:16868554 PMID:21531066 More... RGD:8655885, RGD:8655986 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11333366 PMID:30716316 RGD:27095883 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 exacerbates IDA
IMP		 RGD PMID:23764464 PMID:23884942 RGD:8694326, RGD:8694331 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tert telomerase reverse transcriptase treatment IDA RGD PMID:21914402 RGD:11038669 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO RGD PMID:18067952 RGD:11062087 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein IEP RGD PMID:16055272 RGD:10059581 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586 		JBrowse link
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 IEP RGD PMID:10700014 RGD:1357161 NCBI chr 1:183,008,358...183,045,092
Ensembl chr 1:183,009,253...183,031,637 		JBrowse link
G Tnf tumor necrosis factor treatment IDA
IEP		 mRNA:increased expression:striatum,hippocampus: RGD PMID:24053818 PMID:11412877 RGD:7364868, RGD:13825263 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment IEP mRNA:increased expression:striatum,hippocampus: RGD PMID:21868309 PMID:11412877 RGD:8661762, RGD:13825263 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 treatment IDA
ISO		 RGD PMID:23435869 PMID:20811149 PMID:23043486 RGD:7247582, RGD:7247585, RGD:7247583 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IEP mRNA:increased expression:cerebral cortex RGD PMID:16777714 RGD:10003026 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 ISO RGD PMID:22284622 RGD:7175554 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
G Ucp2 uncoupling protein 2 treatment IDA RGD PMID:19772611 RGD:7204428 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Vwf von Willebrand factor treatment IDA RGD PMID:22771326 RGD:7207039 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 IEP RGD PMID:27798271 RGD:14398833 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 IEP RGD PMID:27798271 RGD:14398833 NCBI chr17:15,503,672...15,612,479
Ensembl chr17:15,504,261...15,612,479 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 IEP RGD PMID:27798271 RGD:14398833 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 treatment IEP RGD PMID:19840223 RGD:2325713 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21126
    Pathological Conditions, Signs and Symptoms 13335
      Pathologic Processes 7990
        ischemia 1499
          brain ischemia 641
            Brain Hypoxia-Ischemia + 105
            Chronic Cerebral Hypoperfusion 17
            brain infarction + 317
            transient cerebral ischemia + 241
Path 2
Term Annotations click to browse term
  disease 21126
    disease of anatomical entity 18216
      nervous system disease 14065
        central nervous system disease 12403
          brain disease 11639
            cerebrovascular disease 1000
              brain ischemia 641
                Brain Hypoxia-Ischemia + 105
                Chronic Cerebral Hypoperfusion 17
                brain infarction + 317
                transient cerebral ischemia + 241
paths to the root