Gene: Kcnk6 (potassium two pore domain channel subfamily K member 6) Rattus norvegicus
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Symbol: Kcnk6
Name: potassium two pore domain channel subfamily K member 6
Description: ENCODES a protein that exhibits potassium channel activity; INVOLVED IN negative regulation of systemic arterial blood pressure (ortholog); regulation of resting membrane potential (ortholog); regulation of systemic arterial blood pressure (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil
AGR Description: Exhibits potassium channel activity; predicted to be involved in several processes, including negative regulation of systemic arterial blood pressure, potassium ion transmembrane transport, and regulation of resting membrane potential; predicted to localize to the integral component of plasma membrane; orthologous to human KCNK6 (potassium two pore domain channel subfamily K member 6).
Merged Description: Exhibits potassium channel activity; predicted to be involved in several processes, including negative regulation of systemic arterial blood pressure, potassium ion transmembrane transport, and regulation of resting membrane potential; predicted to localize to the integral component of plasma membrane; orthologous to human KCNK6 (potassium two pore domain channel subfamily K member 6); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: potassium channel subfamily K member 6 (TWIK-2); potassium channel, subfamily K, member 6; potassium channel, subfamily K, member 6 (TWIK-2); potassium channel, two pore domain subfamily K, member 6; potassium inwardly-rectifying channel, subfamily K, member 6; Twik-2; Twik2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0188,168,438 - 88,176,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0189,343,864 - 89,352,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4184,359,738 - 84,367,910 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1184,404,339 - 84,446,021 (-)NCBI
Celera178,912,886 - 78,921,054 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnk6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621450
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.