Mir107 (microRNA 107) - Rat Genome Database

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Gene: Mir107 (microRNA 107) Rattus norvegicus
Analyze
Symbol: Mir107
Name: microRNA 107
RGD ID: 2325578
Description: Predicted to enable mRNA base-pairing translational repressor activity. Involved in several processes, including cellular response to oxygen-glucose deprivation; positive regulation of angiogenesis; and positive regulation of endothelial cell migration. Predicted to be located in neuronal cell body. Biomarker of middle cerebral artery infarction. Orthologous to human MIR107 (microRNA 107); INTERACTS WITH atrazine; bis(2-ethylhexyl) phthalate; bleomycin A2.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-107
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21232,337,767 - 232,337,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,337,767 - 232,337,853 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,733,793 - 240,733,879 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01247,646,828 - 247,646,914 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01240,485,014 - 240,485,100 (-)NCBIRnor_WKY
Rnor_6.01253,128,250 - 253,128,336 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1253,128,250 - 253,128,336 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01260,347,511 - 260,347,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1229,451,547 - 229,451,633 (-)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Depleted tumor suppressor miR-107 in plasma relates to tumor progression and is a novel therapeutic target in pancreatic cancer. Imamura T, etal., Sci Rep. 2017 Jul 18;7(1):5708. doi: 10.1038/s41598-017-06137-8.
2. MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1. Li Y, etal., Sci Rep. 2015 Aug 21;5:13316. doi: 10.1038/srep13316.
3. Murine hepatic miRNAs expression and regulation of gene expression in diet-induced obese mice. Park JH, etal., Mol Cells. 2011 Jan;31(1):33-8. doi: 10.1007/s10059-011-0009-7. Epub 2010 Nov 25.
4. LncRNA H19 serves as a ceRNA and participates in non-small cell lung cancer development by regulating microRNA-107. Qian B, etal., Eur Rev Med Pharmacol Sci. 2018 Sep;22(18):5946-5953. doi: 10.26355/eurrev_201809_15925.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis. Sarma NJ, etal., J Virol. 2014 Apr;88(7):3733-43. doi: 10.1128/JVI.03060-13. Epub 2014 Jan 15.
7. Biomarkers Associated With Response to Regorafenib in Patients With Hepatocellular Carcinoma. Teufel M, etal., Gastroenterology. 2019 May;156(6):1731-1741. doi: 10.1053/j.gastro.2019.01.261. Epub 2019 Feb 6.
8. MiR-107 suppresses proliferation of hepatoma cells through targeting HMGA2 mRNA 3'UTR. Wang Y, etal., Biochem Biophys Res Commun. 2016 Nov 18;480(3):455-460. doi: 10.1016/j.bbrc.2016.10.070. Epub 2016 Oct 20.
9. miR-107 promotes hepatocellular carcinoma cell proliferation by targeting Axin2. Zhang JJ, etal., Int J Clin Exp Pathol. 2015 May 1;8(5):5168-74. eCollection 2015.
10. Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. Zhang Y, etal., Medicine (Baltimore). 2017 Jan;96(2):e5642. doi: 10.1097/MD.0000000000005642.
11. Characteristic MicroRNA Expression Induced by δ-Opioid Receptor Activation in the Rat Liver Under Prolonged Hypoxia. Zhi F, etal., Cell Physiol Biochem. 2017;44(6):2296-2309. doi: 10.1159/000486067. Epub 2017 Dec 14.
Additional References at PubMed
PMID:16381832   PMID:17604727   PMID:18320040   PMID:18723672   PMID:18762567   PMID:20403161   PMID:20548288   PMID:21415270   PMID:22482882   PMID:22792280   PMID:23646144   PMID:24205035  
PMID:24943094   PMID:26610560   PMID:26827991   PMID:30308117   PMID:33785379   PMID:35093630  


Genomics

Comparative Map Data
Mir107
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21232,337,767 - 232,337,853 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,337,767 - 232,337,853 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,733,793 - 240,733,879 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01247,646,828 - 247,646,914 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01240,485,014 - 240,485,100 (-)NCBIRnor_WKY
Rnor_6.01253,128,250 - 253,128,336 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1253,128,250 - 253,128,336 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01260,347,511 - 260,347,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1229,451,547 - 229,451,633 (-)NCBICelera
Cytogenetic Map1q53NCBI
MIR107
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381089,592,747 - 89,592,827 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1089,592,747 - 89,592,827 (-)EnsemblGRCh38hg38GRCh38
GRCh371091,352,504 - 91,352,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361091,342,483 - 91,342,563 (-)NCBINCBI36Build 36hg18NCBI36
Celera1085,099,321 - 85,099,401 (-)NCBICelera
Cytogenetic Map10q23.31NCBI
HuRef1084,986,456 - 84,986,536 (-)NCBIHuRef
CHM1_11091,634,601 - 91,634,681 (-)NCBICHM1_1
T2T-CHM13v2.01090,476,644 - 90,476,724 (-)NCBIT2T-CHM13v2.0
Mir107
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,798,087 - 34,798,173 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1934,798,087 - 34,798,173 (-)EnsemblGRCm39 Ensembl
GRCm381934,820,687 - 34,820,773 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,820,687 - 34,820,773 (-)EnsemblGRCm38mm10GRCm38
MGSCv371934,895,177 - 34,895,263 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1935,597,534 - 35,597,620 (-)NCBICelera
Cytogenetic Map19C1NCBI
MIR107
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,484,653 - 4,484,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,484,646 - 4,484,718 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha284,719,130 - 4,719,187 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0284,706,547 - 4,706,604 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1284,456,978 - 4,457,035 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0284,499,421 - 4,499,478 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0284,635,242 - 4,635,299 (-)NCBIUU_Cfam_GSD_1.0
MIR107
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14101,420,743 - 101,420,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114101,420,743 - 101,420,829 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214110,407,095 - 110,407,181 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:15750
Count of gene targets:8233
Count of transcripts:8960
Interacting mature miRNAs:rno-miR-107-3p, rno-miR-107-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210702053240947965Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
2292216Bw80Body weight QTL 803.230.0019body mass (VT:0001259)body weight (CMO:0000012)1213533809243914901Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1218753689245907899Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1224054293243747962Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1224054293243747962Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228985440245907899Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 4 18 7 9 7 6 6 6 8 8 2 6
Below cutoff 3 2 2 1 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000053762
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1232,337,767 - 232,337,853 (-)Ensembl
Rnor_6.0 Ensembl1253,128,250 - 253,128,336 (-)Ensembl
RefSeq Acc Id: NR_031863
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21232,337,767 - 232,337,853 (-)NCBI
Rnor_6.01253,128,250 - 253,128,336 (-)NCBI
Rnor_5.01260,347,511 - 260,347,597 (-)NCBI
Celera1229,451,547 - 229,451,633 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325578 AgrOrtholog
BioCyc Gene G2FUF-55862 BioCyc
Ensembl Genes ENSRNOG00000035639 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053762 ENTREZGENE
miRBase MI0000890 ENTREZGENE
NCBI Gene 100314022 ENTREZGENE
PhenoGen Mir107 PhenoGen
RNAcentral URS00005743AE RNACentral
  URS000075E00A RNACentral
  URS000075E2AC RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir107  microRNA 107  Mir107  microRNA mir-107  Name updated 61478 APPROVED
2010-06-02 Mir107  microRNA mir-107      Symbol and Name status set to provisional 70820 PROVISIONAL