Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Epn1 (Epsin 1) Rattus norvegicus
Analyze
Symbol: Epn1
Name: Epsin 1
Description: Exhibits clathrin adaptor activity; ion channel binding activity; and transcription factor binding activity. Involved in endocytosis and positive regulation of clathrin coat assembly. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; extrinsic component of cytoplasmic side of plasma membrane; and extrinsic component of synaptic membrane. Biomarker of middle cerebral artery infarction. Orthologous to human EPN1 (epsin 1); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: EPS-15-interacting protein 1; epsin-1
Orthologs:
Homo sapiens (human) : EPN1 (epsin 1)  HGNC  Alliance
Mus musculus (house mouse) : Epn1 (epsin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epn1 (epsin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPN1 (epsin 1)
Canis lupus familiaris (dog) : EPN1 (epsin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epn1 (epsin 1)
Sus scrofa (pig) : EPN1 (epsin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0172,294,153 - 72,310,217 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl172,294,153 - 72,311,856 (-)Ensembl
Rnor_5.0176,226,173 - 76,242,237 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,479,998 - 67,496,066 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1167,558,113 - 67,574,177 (-)NCBI
Celera168,360,140 - 68,376,208 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Epn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619772
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.