Mir383 (microRNA 383) - Rat Genome Database

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Gene: Mir383 (microRNA 383) Rattus norvegicus
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Symbol: Mir383
Name: microRNA 383
RGD ID: 2325533
Description: Predicted to enable mRNA base-pairing post-transcriptional repressor activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing and negative regulation of interleukin-17 production. Predicted to act upstream of or within cellular response to lipopolysaccharide; long-term synaptic potentiation; and sensory perception of sound. Predicted to be part of RISC complex. Biomarker of cerebral infarction. Orthologous to human MIR383 (microRNA 383); INTERACTS WITH atrazine; bis(2-ethylhexyl) phthalate; cadmium dichloride.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-383
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81660,743,764 - 60,743,837 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1660,743,764 - 60,743,837 (+)EnsemblGRCr8
mRatBN7.21654,040,340 - 54,040,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1654,040,340 - 54,040,413 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1659,345,559 - 59,345,632 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01662,762,511 - 62,762,584 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01657,979,548 - 57,979,621 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1660,661,877 - 60,661,950 (+)NCBI
Lyon_Normotensive1662,048,361 - 62,048,434 (+)NCBI
Lyon_Hypertensive1662,522,321 - 62,522,394 (+)NCBI
F344_StmMcwi1658,690,613 - 58,690,686 (+)NCBI
Rnor_6.01657,519,675 - 57,519,748 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1657,519,675 - 57,519,748 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01657,201,649 - 57,201,722 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1651,913,639 - 51,913,712 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. EPO-cyclosporine combination therapy reduced brain infarct area in rat after acute ischemic stroke: role of innate immune-inflammatory response, micro-RNAs and MAPK family signaling pathway. Yuen CM, etal., Am J Transl Res. 2017 Apr 15;9(4):1651-1666. eCollection 2017.
Additional References at PubMed
PMID:16274478   PMID:16381832   PMID:20403161   PMID:21247879   PMID:23646144   PMID:25858512   PMID:27607022   PMID:29909059   PMID:32090391   PMID:33819732   PMID:33927285   PMID:35927544  


Genomics

Comparative Map Data
Mir383
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81660,743,764 - 60,743,837 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1660,743,764 - 60,743,837 (+)EnsemblGRCr8
mRatBN7.21654,040,340 - 54,040,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1654,040,340 - 54,040,413 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1659,345,559 - 59,345,632 (+)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01662,762,511 - 62,762,584 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01657,979,548 - 57,979,621 (+)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1660,661,877 - 60,661,950 (+)NCBI
Lyon_Normotensive1662,048,361 - 62,048,434 (+)NCBI
Lyon_Hypertensive1662,522,321 - 62,522,394 (+)NCBI
F344_StmMcwi1658,690,613 - 58,690,686 (+)NCBI
Rnor_6.01657,519,675 - 57,519,748 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1657,519,675 - 57,519,748 (+)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01657,201,649 - 57,201,722 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1651,913,639 - 51,913,712 (+)NCBICelera
Cytogenetic Map16q12.1NCBI
MIR383
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38814,853,438 - 14,853,510 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl814,853,438 - 14,853,510 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37814,710,947 - 14,711,019 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36814,755,317 - 14,755,389 (-)NCBIBuild 36Build 36hg18NCBI36
Celera813,675,794 - 13,675,866 (-)NCBICelera
Cytogenetic Map8p22NCBI
HuRef813,253,306 - 13,253,378 (-)NCBIHuRef
CHM1_1814,912,423 - 14,912,495 (-)NCBICHM1_1
T2T-CHM13v2.0815,119,396 - 15,119,468 (-)NCBIT2T-CHM13v2.0
Mir383
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39838,719,287 - 38,719,356 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl838,719,287 - 38,719,356 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38838,252,133 - 38,252,202 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl838,252,133 - 38,252,202 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37839,315,187 - 39,315,256 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera840,936,617 - 40,936,686 (-)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.89NCBI
MIR383
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11638,173,722 - 38,173,783 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1638,173,693 - 38,173,803 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1638,644,674 - 38,644,735 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01640,214,645 - 40,214,706 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.11638,302,940 - 38,303,001 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01638,867,325 - 38,867,386 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01638,991,209 - 38,991,270 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
MIR383
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl172,698,041 - 2,698,122 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1172,698,041 - 2,698,122 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2172,603,744 - 2,603,825 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir383
1 total Variants
miRNA Target Status (No longer updated)

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Neurod1rno-miR-383-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)18258830

Predicted Targets
Summary Value
Count of predictions:9322
Count of gene targets:5467
Count of transcripts:5876
Interacting mature miRNAs:rno-miR-383-3p, rno-miR-383-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)164445512389455123Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)163692878281928782Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)164199206486992064Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162846870173468701Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164909919691442908Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)163236104377361043Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165942871491442908Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)163105803976058039Rat
1298529Arunc1Aerobic running capacity QTL 14exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)163439829479398294Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)163188527176885271Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)164445512389455123Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165942871491442908Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165942871491442908Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat


Expression

RNA-SEQ Expression

ectoderm
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
11 1 1 8 7 11 7 7 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_032106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000053712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1660,743,764 - 60,743,837 (+)Ensembl
mRatBN7.2 Ensembl1654,040,340 - 54,040,413 (+)Ensembl
Rnor_6.0 Ensembl1657,519,675 - 57,519,748 (+)Ensembl
RefSeq Acc Id: NR_032106
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81660,743,764 - 60,743,837 (+)NCBI
mRatBN7.21654,040,340 - 54,040,413 (+)NCBI
Dahl_SR_JrHsd1660,661,877 - 60,661,950 (+)NCBI
Lyon_Normotensive1662,048,361 - 62,048,434 (+)NCBI
Lyon_Hypertensive1662,522,321 - 62,522,394 (+)NCBI
F344_StmMcwi1658,690,613 - 58,690,686 (+)NCBI
Rnor_6.01657,519,675 - 57,519,748 (+)NCBI
Rnor_5.01657,201,649 - 57,201,722 (+)NCBI
Celera1651,913,639 - 51,913,712 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325533 AgrOrtholog
BioCyc Gene G2FUF-11211 BioCyc
Ensembl Genes ENSRNOG00000035589 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053712 ENTREZGENE
miRBase MI0003478 ENTREZGENE
NCBI Gene 100314072 ENTREZGENE
PhenoGen Mir383 PhenoGen
RatGTEx ENSRNOG00000035589 RatGTEx
RNAcentral URS0000406128 RNACentral
  URS000075C5C2 RNACentral
  URS000075D80E RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir383  microRNA 383  Mir383  microRNA mir-383  Name updated 61478 APPROVED
2010-06-02 Mir383  microRNA mir-383      Symbol and Name status set to provisional 70820 PROVISIONAL