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Gene: Atp2b2 (ATPase plasma membrane Ca2+ transporting 2) Rattus norvegicus
Symbol: Atp2b2
Name: ATPase plasma membrane Ca2+ transporting 2
RGD ID: 2176
Description: Exhibits several functions, including ATP binding activity; PDZ domain binding activity; and calcium transmembrane transporter activity, phosphorylative mechanism. Involved in brain development and neural retina development. Localizes to several cellular components, including glutamatergic synapse; integral component of postsynaptic density membrane; and neuronal cell body membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
Also known as: ATPase isoform 2 Na+K+ transporting beta polypeptide 2; ATPase isoform 2, Na+K+ transporting, beta polypeptide 2; ATPase, Ca++ transporting, plasma membrane 2; plasma membrane Ca++-ATPase; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 2; PMCA2
Homo sapiens (human) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)  HGNC  Alliance
Mus musculus (house mouse) : Atp2b2 (ATPase, Ca++ transporting, plasma membrane 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Canis lupus familiaris (dog) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Sus scrofa (pig) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Chlorocebus sabaeus (African green monkey) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Heterocephalus glaber (naked mole-rat) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04145,704,779 - 145,948,997 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4145,703,046 - 146,016,325 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04209,001,178 - 209,242,860 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,655,651 - 149,907,813 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14149,903,289 - 150,220,388 (-)NCBI
Celera4135,451,009 - 135,760,704 (-)NCBICelera
Cytogenetic Map4q42NCBI
RH 3.4 Map4948.3RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Atp2b2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2176
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.