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Gene: Atp2b2 (ATPase, Ca++ transporting, plasma membrane 2) Mus musculus
Symbol: Atp2b2
Name: ATPase, Ca++ transporting, plasma membrane 2
RGD ID: 10211
Description: Exhibits calcium-dependent ATPase activity. Involved in several processes, including animal organ development; cGMP metabolic process; and detection of mechanical stimulus involved in sensory perception of sound. Localizes to several cellular components, including apical plasma membrane; endoplasmic reticulum; and neuronal cell body. Is expressed in heart; liver; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D6Abb2; D6Abb2e; deaf waddler; dfw; Gena3; Gena300; jo; jog; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-transporting ATPase 2; PMC; PMCA2; Tmy; wm; wms; wri; wriggle
Homo sapiens (human) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Canis lupus familiaris (dog) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
Sus scrofa (pig) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Chlorocebus sabaeus (African green monkey) : ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Heterocephalus glaber (naked mole-rat) : Atp2b2 (ATPase plasma membrane Ca2+ transporting 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl6113,743,831 - 114,042,613 (-)EnsemblGRCm38mm10GRCm38
GRCm386113,743,831 - 114,042,613 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376113,695,662 - 113,992,020 (-)NCBIGRCm37mm9NCBIm37
MGSCv366113,711,445 - 114,007,621 (-)NCBImm8
Celera6115,571,179 - 115,799,955 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Atp2b2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10211
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.