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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antidyskinesia agent
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Accession:CHEBI:66956 term browser browse the term
Definition:Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
Synonyms:related_synonym: antidyskinesia agents;   antidyskinesia drug;   antidyskinesia drugs;   antidyskinetic agent;   antidyskinetic agents;   antidyskinetic drug;   antidyskinetic drugs



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(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd1 dopamine receptor D1 multiple interactions
affects localization
ISO A 77636 binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein] CTD PMID:15985612 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
amantadine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor multiple interactions ISO [Fluoxetine co-treated with Amantadine] results in increased expression of BDNF mRNA CTD PMID:19211973 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO Amantadine results in increased expression of IFI27 mRNA CTD PMID:16756086 NCBI chr12:103,400,448...103,406,504
Ensembl chr12:103,400,470...103,406,498
JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 affects expression ISO Amantadine affects the expression of IFNAR1 mRNA CTD PMID:16756086 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Amantadine results in increased expression of JAK1 protein CTD PMID:16756086 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Amantadine results in decreased activity of KCNH2 protein CTD PMID:21158687 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO Amantadine results in decreased expression of MAP2 mRNA CTD PMID:34748853 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Amantadine results in increased expression of OAS2 mRNA CTD PMID:16756086 NCBI chr 5:120,868,398...120,887,949
Ensembl chr 5:120,868,398...120,887,918
JBrowse link
G Slc47a1 solute carrier family 47, member 1 multiple interactions ISO Amantadine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc47a2 solute carrier family 47, member 2 multiple interactions ISO Amantadine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr11:61,192,453...61,233,686
Ensembl chr11:61,192,457...61,233,686
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Amantadine co-treated with Ursodeoxycholic Acid co-treated with 7,7'-dimethoxy-(4,4'-bi-1,3-benzodioxole)-5,5'-dicarboxylic acid dimethyl ester] results in increased activity of STAT1 CTD PMID:15918519 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 decreases activity ISO Amantadine analog results in decreased activity of TDP1 protein CTD PMID:29248742 NCBI chr12:99,850,767...99,921,482
Ensembl chr12:99,850,776...99,921,478
JBrowse link
apomorphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin increases expression
multiple interactions
ISO Apomorphine results in increased expression of AVP protein
Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein]
CTD PMID:16575035 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form] CTD PMID:25633564 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Bmpr1a bone morphogenetic protein receptor, type 1A decreases expression ISO Apomorphine results in decreased expression of BMPR1A mRNA CTD PMID:25633564 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298
JBrowse link
G Cck cholecystokinin multiple interactions
decreases activity
ISO Naloxone inhibits the reaction [CCK protein results in decreased activity of Apomorphine] CTD PMID:3561887 NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760
JBrowse link
G Cckbr cholecystokinin B receptor affects response to substance EXP CCKBR protein affects the susceptibility to Apomorphine CTD PMID:11702094 NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Apomorphine results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO
EXP
Apomorphine binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
CTD PMID:8103921 PMID:15985612 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects response to substance
increases response to substance
EXP
ISO
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein]
DRD2 protein affects the susceptibility to Apomorphine
DRD2 protein results in increased susceptibility to Apomorphine
CTD PMID:2571179 PMID:7520908 PMID:8103596 PMID:8103921 PMID:14639100 More... NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 increases response to substance EXP DRD3 protein results in increased susceptibility to Apomorphine CTD PMID:19497322 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO Apomorphine results in increased expression of FOS protein CTD PMID:10904129 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Furin furin, paired basic amino acid cleaving enzyme decreases expression ISO Apomorphine results in decreased expression of FURIN mRNA CTD PMID:25633564 NCBI chr 7:80,038,942...80,055,188
Ensembl chr 7:80,038,333...80,055,184
JBrowse link
G Gdnf glial cell line derived neurotrophic factor multiple interactions ISO GDNF protein affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Gh growth hormone increases secretion
increases expression
ISO Apomorphine results in increased secretion of GH1 protein
Apomorphine results in increased expression of GH1 protein
CTD PMID:993808 PMID:8889285 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases secretion
decreases expression
ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]; Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Apomorphine results in decreased secretion of HAMP protein modified form
Apomorphine results in decreased expression of HAMP mRNA
CTD PMID:25633564 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions ISO [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] CTD PMID:8539317 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Htr6 5-hydroxytryptamine (serotonin) receptor 6 increases response to substance
multiple interactions
ISO HTR6 protein results in increased susceptibility to Apomorphine
Ro4368554 inhibits the reaction [HTR6 protein results in increased susceptibility to Apomorphine]
CTD PMID:17920665 NCBI chr 4:138,787,017...138,802,881
Ensembl chr 4:138,788,419...138,802,881
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO Apomorphine inhibits the reaction [Oxidopamine results in increased phosphorylation of JUN protein] CTD PMID:14599342 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 increases activity EXP Apomorphine results in increased activity of ODC1 protein CTD PMID:10354516 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
JBrowse link
G Penk preproenkephalin multiple interactions ISO Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA] CTD PMID:17719177 NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819
JBrowse link
G Prl prolactin decreases expression ISO Apomorphine results in decreased expression of PRL protein CTD PMID:8889285 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Pvalb parvalbumin affects expression ISO Apomorphine affects the expression of PVALB protein CTD PMID:15238432 NCBI chr15:78,075,312...78,090,600
Ensembl chr15:78,075,314...78,090,600
JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance EXP RGS9 affects the susceptibility to Apomorphine CTD PMID:15728856 NCBI chr11:109,116,174...109,189,013
Ensembl chr11:109,116,181...109,188,955
JBrowse link
G Shh sonic hedgehog multiple interactions ISO SHH protein modified form affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Apomorphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Syt7 synaptotagmin VII multiple interactions ISO [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544
JBrowse link
G Tac1 tachykinin 1 multiple interactions ISO Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:17719177 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
benserazide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of Benserazide CTD PMID:11160877 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Ddc dopa decarboxylase multiple interactions ISO Benserazide binds to and results in decreased activity of DDC protein CTD PMID:35151785 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO [Oxidopamine co-treated with levodopa methyl ester] promotes the reaction [Benserazide results in increased expression of DRD1 protein] CTD PMID:19399396 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO [Oxidopamine co-treated with levodopa methyl ester] inhibits the reaction [Benserazide results in increased expression of DRD2 protein] CTD PMID:19399396 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
benzatropine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A930009A15Rik RIKEN cDNA A930009A15 gene decreases expression ISO Benztropine results in decreased expression of DCD protein CTD PMID:34122009 NCBI chr10:115,399,555...115,418,359
Ensembl chr10:115,405,891...115,418,353
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases activity ISO Benztropine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Benztropine results in increased expression of ACOT2 protein CTD PMID:34122009 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Benztropine results in increased expression of ACTBL2 protein CTD PMID:34122009 NCBI chr13:111,391,547...111,394,283
Ensembl chr13:111,391,547...111,394,283
JBrowse link
G Actr1a ARP1 actin-related protein 1A, centractin alpha multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ACTR1A protein CTD PMID:34122009 NCBI chr19:46,365,252...46,384,180
Ensembl chr19:46,365,250...46,384,187
JBrowse link
G Actr3 ARP3 actin-related protein 3 decreases expression ISO Benztropine results in decreased expression of ACTR3 protein CTD PMID:34122009 NCBI chr 1:125,320,642...125,363,464
Ensembl chr 1:125,320,642...125,363,464
JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr15:80,832,691...80,855,148
Ensembl chr15:80,832,691...80,855,147
JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 2:75,662,477...75,761,694
Ensembl chr 2:75,662,521...75,761,694
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Benztropine results in decreased expression of AK1 protein CTD PMID:34122009 NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070
JBrowse link
G Anxa1 annexin A1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ANXA1 protein CTD PMID:34122009 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
JBrowse link
G Anxa5 annexin A5 decreases expression ISO Benztropine results in decreased expression of ANXA5 protein CTD PMID:34122009 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Anxa6 annexin A6 decreases expression ISO Benztropine results in decreased expression of ANXA6 protein CTD PMID:34122009 NCBI chr11:54,869,779...54,924,297
Ensembl chr11:54,869,934...54,924,271
JBrowse link
G Anxa7 annexin A7 increases expression ISO Benztropine results in increased expression of ANXA7 protein CTD PMID:34122009 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201
JBrowse link
G Armt1 acidic residue methyltransferase 1 increases expression ISO Benztropine results in increased expression of ARMT1 protein CTD PMID:34122009 NCBI chr10:4,382,572...4,405,140
Ensembl chr10:4,382,467...4,405,141
JBrowse link
G Asns asparagine synthetase decreases expression ISO Benztropine results in decreased expression of ASNS protein CTD PMID:34122009 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Benztropine results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 4:9,449,085...9,669,344
Ensembl chr 4:9,448,069...9,669,344
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous increases expression ISO Benztropine results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ATP5F1C protein CTD PMID:34122009 NCBI chr 2:10,060,841...10,085,321
Ensembl chr 2:10,060,827...10,085,321
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 decreases expression ISO Benztropine results in decreased expression of ATP6V1B2 protein CTD PMID:34122009 NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
JBrowse link
G Atxn10 ataxin 10 increases expression ISO Benztropine results in increased expression of ATXN10 protein CTD PMID:34122009 NCBI chr15:85,220,456...85,348,038
Ensembl chr15:85,220,446...85,347,413
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BAZ1B protein CTD PMID:34122009 NCBI chr 5:135,214,094...135,274,985
Ensembl chr 5:135,216,118...135,274,983
JBrowse link
G Bcar1 breast cancer anti-estrogen resistance 1 decreases expression ISO Benztropine results in decreased expression of BCAR1 protein CTD PMID:34122009 NCBI chr 8:112,437,106...112,470,481
Ensembl chr 8:112,437,106...112,470,441
JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BLTP1 protein CTD PMID:34122009 NCBI chr 3:36,917,212...37,107,182
Ensembl chr 3:36,917,253...37,107,182
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Benztropine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Brd2 bromodomain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of BRD2 protein CTD PMID:34122009 NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608
JBrowse link
G Bsg basigin decreases expression ISO Benztropine results in decreased expression of BSG protein CTD PMID:34122009 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803
JBrowse link
G Cald1 caldesmon 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CALD1 protein
Benztropine results in decreased expression of CALD1 protein
CTD PMID:34122009 NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408
JBrowse link
G Calu calumenin decreases expression ISO Benztropine results in decreased expression of CALU protein CTD PMID:34122009 NCBI chr 6:29,348,105...29,376,674
Ensembl chr 6:29,348,068...29,377,109
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CAMK2D protein CTD PMID:34122009 NCBI chr 3:126,389,136...126,639,975
Ensembl chr 3:126,389,951...126,639,975
JBrowse link
G Caprin1 cell cycle associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CAPRIN1 protein CTD PMID:34122009 NCBI chr 2:103,593,292...103,627,946
Ensembl chr 2:103,593,286...103,627,994
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CASP8AP2 protein CTD PMID:34122009 NCBI chr 4:32,615,462...32,653,271
Ensembl chr 4:32,615,451...32,653,265
JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr15:103,099,973...103,148,337
Ensembl chr15:103,099,971...103,148,243
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Benztropine results in increased expression of CCAR1 protein CTD PMID:34122009 NCBI chr10:62,579,707...62,628,147
Ensembl chr10:62,579,707...62,628,065
JBrowse link
G Ccdc121 coiled-coil domain containing 121 increases expression ISO Benztropine results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr 5:31,643,205...31,645,820
Ensembl chr 5:31,643,084...31,645,820
JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT6A protein CTD PMID:34122009 NCBI chr 5:129,864,420...129,875,284
Ensembl chr 5:129,864,062...129,875,212
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Benztropine results in decreased expression of CCT7 protein CTD PMID:34122009 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr16:87,280,213...87,292,757
Ensembl chr16:87,280,214...87,292,761
JBrowse link
G Cd276 CD276 antigen decreases expression ISO Benztropine results in decreased expression of CD276 protein CTD PMID:34122009 NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720
JBrowse link
G Cenpv centromere protein V increases expression ISO Benztropine results in increased expression of CENPV protein CTD PMID:34122009 NCBI chr11:62,415,770...62,430,695
Ensembl chr11:62,415,772...62,430,087
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases expression ISO Benztropine results in decreased expression of CHD4 protein CTD PMID:34122009 NCBI chr 6:125,073,144...125,107,554
Ensembl chr 6:125,072,944...125,107,554
JBrowse link
G Ckb creatine kinase, brain multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of CKB protein CTD PMID:34122009 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression
multiple interactions
ISO Benztropine results in decreased expression of CNP protein
[Cuprizone co-treated with Benztropine] results in decreased expression of CNP protein
CTD PMID:34122009 NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555
JBrowse link
G Col14a1 collagen, type XIV, alpha 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL14A1 protein CTD PMID:34122009 NCBI chr15:55,171,040...55,384,199
Ensembl chr15:55,171,146...55,384,199
JBrowse link
G Col5a2 collagen, type V, alpha 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of COL5A2 protein CTD PMID:34122009 NCBI chr 1:45,413,491...45,542,442
Ensembl chr 1:45,413,481...45,542,442
JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Benztropine results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr 5:100,666,223...100,695,668
Ensembl chr 5:100,666,175...100,695,669
JBrowse link
G Coro1b coronin, actin binding protein 1B decreases expression ISO Benztropine results in decreased expression of CORO1B protein CTD PMID:34122009 NCBI chr19:4,198,610...4,204,034
Ensembl chr19:4,198,618...4,204,034
JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CORO7 protein CTD PMID:34122009 NCBI chr16:4,444,748...4,497,584
Ensembl chr16:4,443,997...4,497,641
JBrowse link
G Cpne3 copine III decreases expression ISO Benztropine results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 4:19,519,252...19,570,108
Ensembl chr 4:19,519,254...19,570,108
JBrowse link
G Cpsf3 cleavage and polyadenylation specificity factor 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CPSF3 protein CTD PMID:34122009 NCBI chr12:21,336,298...21,365,057
Ensembl chr12:21,335,392...21,365,057
JBrowse link
G Crtap cartilage associated protein increases expression ISO Benztropine results in increased expression of CRTAP protein CTD PMID:34122009 NCBI chr 9:114,204,204...114,219,743
Ensembl chr 9:114,204,202...114,219,743
JBrowse link
G Cryz crystallin, zeta multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CRYZ protein CTD PMID:34122009 NCBI chr 3:154,302,348...154,328,819
Ensembl chr 3:154,302,348...154,328,819
JBrowse link
G Csde1 cold shock domain containing E1, RNA binding multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CSDE1 protein CTD PMID:34122009 NCBI chr 3:102,927,347...102,965,502
Ensembl chr 3:102,927,742...102,965,502
JBrowse link
G Cstf2 cleavage stimulation factor, 3' pre-RNA subunit 2 decreases expression ISO Benztropine results in decreased expression of CSTF2 protein CTD PMID:34122009 NCBI chr  X:132,959,925...132,987,571
Ensembl chr  X:132,959,936...132,987,568
JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CTBP1 protein CTD PMID:34122009 NCBI chr 5:33,405,067...33,432,348
Ensembl chr 5:33,405,067...33,432,338
JBrowse link
G Cul2 cullin 2 increases expression ISO Benztropine results in increased expression of CUL2 protein CTD PMID:34122009 NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
JBrowse link
G Cul4b cullin 4B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of CUL4B protein CTD PMID:34122009 NCBI chr  X:37,620,493...37,665,073
Ensembl chr  X:37,622,151...37,665,073
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO Benztropine results in increased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DARS2 protein CTD PMID:34122009 NCBI chr 1:160,868,171...160,898,236
Ensembl chr 1:160,868,171...160,898,228
JBrowse link
G Dazap1 DAZ associated protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DAZAP1 protein CTD PMID:34122009 NCBI chr10:80,097,168...80,124,242
Ensembl chr10:80,097,320...80,124,242
JBrowse link
G Dctn2 dynactin 2 increases expression ISO Benztropine results in increased expression of DCTN2 protein CTD PMID:34122009 NCBI chr10:127,102,131...127,117,828
Ensembl chr10:127,102,237...127,117,819
JBrowse link
G Ddx17 DEAD box helicase 17 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX17 protein CTD PMID:34122009 NCBI chr15:79,411,897...79,430,976
Ensembl chr15:79,411,937...79,430,942
JBrowse link
G Ddx3x DEAD box helicase 3, X-linked multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DDX3X protein CTD PMID:34122009 NCBI chr  X:13,147,261...13,160,222
Ensembl chr  X:13,147,209...13,160,291
JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Benztropine results in decreased expression of DGCR6 protein CTD PMID:34122009 NCBI chr16:17,870,736...17,889,497
Ensembl chr16:17,870,724...17,889,496
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Benztropine results in increased expression of DHCR24 protein CTD PMID:34122009 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhx8 DEAH-box helicase 8 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DHX8 protein CTD PMID:34122009 NCBI chr11:101,623,782...101,658,184
Ensembl chr11:101,623,745...101,658,184
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase increases expression
multiple interactions
ISO Benztropine results in increased expression of DLAT protein
[Cuprizone co-treated with Benztropine] results in decreased expression of DLAT protein
CTD PMID:34122009 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Benztropine results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 7:90,125,399...92,098,454
Ensembl chr 7:90,125,880...92,098,455
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Benztropine results in increased expression of DNAJB11 protein CTD PMID:34122009 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384
JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of DPP3 protein CTD PMID:34122009 NCBI chr19:4,957,257...4,978,315
Ensembl chr19:4,957,257...4,978,315
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Benztropine results in decreased expression of DPYSL2 protein CTD PMID:34122009 NCBI chr14:67,040,313...67,148,490
Ensembl chr14:67,040,313...67,106,137
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of DPYSL3 protein CTD PMID:34122009 NCBI chr18:43,454,044...43,571,354
Ensembl chr18:43,454,049...43,571,351
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression ISO Benztropine results in decreased expression of DYNC1LI1 protein CTD PMID:34122009 NCBI chr 9:114,517,899...114,552,856
Ensembl chr 9:114,517,858...114,553,370
JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EBNA1BP2 protein CTD PMID:34122009 NCBI chr 4:118,477,996...118,484,973
Ensembl chr 4:118,477,996...118,484,973
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843
JBrowse link
G Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked increases expression ISO Benztropine results in increased expression of EIF2S3 protein CTD PMID:34122009 NCBI chr  X:93,232,315...93,256,257
Ensembl chr  X:93,232,313...93,256,468
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3B protein CTD PMID:34122009 NCBI chr 5:140,405,060...140,429,113
Ensembl chr 5:140,405,083...140,429,115
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF3C protein CTD PMID:34122009 NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583
JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H decreases expression ISO Benztropine results in decreased expression of EIF3H protein CTD PMID:34122009 NCBI chr15:51,649,956...51,728,901
Ensembl chr15:51,649,954...51,728,919
JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L increases expression
multiple interactions
ISO Benztropine results in increased expression of EIF3L protein
[Cuprizone co-treated with Benztropine] results in decreased expression of EIF3L protein
CTD PMID:34122009 NCBI chr15:78,959,423...78,978,600
Ensembl chr15:78,959,379...78,978,605
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5 protein CTD PMID:34122009 NCBI chr12:111,504,535...111,513,187
Ensembl chr12:111,504,450...111,513,186
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B multiple interactions
increases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EIF5B protein
Benztropine results in increased expression of EIF5B protein
CTD PMID:34122009 NCBI chr 1:38,037,091...38,094,660
Ensembl chr 1:38,037,091...38,094,660
JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Benztropine results in decreased expression of EIF6 protein CTD PMID:34122009 NCBI chr 2:155,661,757...155,668,845
Ensembl chr 2:155,661,752...155,668,845
JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression ISO Benztropine results in decreased expression of ENO1 protein CTD PMID:34122009 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
JBrowse link
G Ephb3 Eph receptor B3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EPHB3 protein CTD PMID:34122009 NCBI chr16:21,023,530...21,042,054
Ensembl chr16:21,023,505...21,042,055
JBrowse link
G Epn1 epsin 1 decreases expression ISO Benztropine results in decreased expression of EPN1 protein CTD PMID:34122009 NCBI chr 7:5,083,207...5,101,178
Ensembl chr 7:5,083,234...5,101,177
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO Benztropine results in decreased expression of EPS8 protein CTD PMID:34122009 NCBI chr 6:137,454,242...137,626,262
Ensembl chr 6:137,454,243...137,631,874
JBrowse link
G Erh ERH mRNA splicing and mitosis factor increases expression ISO Benztropine results in increased expression of ERH protein CTD PMID:34122009 NCBI chr12:80,680,799...80,690,616
Ensembl chr12:80,680,796...80,691,115
JBrowse link
G Erlin2 ER lipid raft associated 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of ERLIN2 protein CTD PMID:34122009 NCBI chr 8:27,513,399...27,529,465
Ensembl chr 8:27,513,289...27,530,356
JBrowse link
G Ewsr1 Ewing sarcoma breakpoint region 1 decreases expression ISO Benztropine results in decreased expression of EWSR1 protein CTD PMID:34122009 NCBI chr11:5,019,687...5,049,314
Ensembl chr11:5,019,689...5,049,266
JBrowse link
G Exosc9 exosome component 9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of EXOSC9 protein CTD PMID:34122009 NCBI chr 3:36,606,755...36,619,876
Ensembl chr 3:36,606,755...36,619,876
JBrowse link
G Ezr ezrin decreases expression ISO Benztropine results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart increases expression ISO Benztropine results in increased expression of FABP3 protein CTD PMID:34122009 NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256
JBrowse link
G Fdps farnesyl diphosphate synthetase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FDPS protein CTD PMID:34122009 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266
JBrowse link
G Flot2 flotillin 2 increases expression ISO Benztropine results in increased expression of FLOT2 protein CTD PMID:34122009 NCBI chr11:77,928,757...77,951,260
Ensembl chr11:77,928,757...77,951,260
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 decreases expression ISO Benztropine results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Fyco1 FYVE and coiled-coil domain containing 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of FYCO1 protein CTD PMID:34122009 NCBI chr 9:123,618,565...123,681,110
Ensembl chr 9:123,618,565...123,680,964
JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of G3BP2 protein CTD PMID:34122009 NCBI chr 5:92,200,004...92,285,584
Ensembl chr 5:92,200,005...92,231,578
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked decreases expression ISO Benztropine results in decreased expression of G6PD protein CTD PMID:34122009 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr 8:124,958,133...125,072,461
Ensembl chr 8:124,958,130...125,072,463
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GART protein CTD PMID:34122009 NCBI chr16:91,418,283...91,444,505
Ensembl chr16:91,418,074...91,443,840
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GATAD2B protein CTD PMID:34122009 NCBI chr 3:90,200,488...90,270,712
Ensembl chr 3:90,200,485...90,270,714
JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GDA protein CTD PMID:34122009 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 decreases expression ISO Benztropine results in decreased expression of GFPT1 protein CTD PMID:34122009 NCBI chr 6:87,019,828...87,069,189
Ensembl chr 6:87,019,828...87,069,179
JBrowse link
G Ggct gamma-glutamyl cyclotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GGCT protein CTD PMID:34122009 NCBI chr 6:54,962,080...54,969,947
Ensembl chr 6:54,959,565...54,969,935
JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Benztropine results in increased expression of GLRX3 protein CTD PMID:34122009 NCBI chr 7:137,039,302...137,071,360
Ensembl chr 7:137,039,343...137,070,323
JBrowse link
G Gls glutaminase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GLS protein CTD PMID:34122009 NCBI chr 1:52,202,608...52,274,168
Ensembl chr 1:52,202,607...52,272,391
JBrowse link
G Gna12 guanine nucleotide binding protein, alpha 12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GNA12 protein CTD PMID:34122009 NCBI chr 5:140,745,699...140,816,186
Ensembl chr 5:140,744,163...140,816,186
JBrowse link
G Golga4 golgin A4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOLGA4 protein CTD PMID:34122009 NCBI chr 9:118,335,280...118,411,587
Ensembl chr 9:118,335,335...118,411,587
JBrowse link
G Golgb1 golgin B1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GOLGB1 protein CTD PMID:34122009 NCBI chr16:36,695,455...36,753,447
Ensembl chr16:36,695,502...36,753,447
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of GOT2 protein CTD PMID:34122009 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpi1 glucose-6-phosphate isomerase 1 increases expression ISO Benztropine results in increased expression of GPI protein CTD PMID:34122009 NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761
JBrowse link
G Gpkow G patch domain and KOW motifs multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GPKOW protein CTD PMID:34122009 NCBI chr  X:7,563,373...7,576,500
Ensembl chr  X:7,563,370...7,576,501
JBrowse link
G Gtf2e1 general transcription factor II E, polypeptide 1 (alpha subunit) decreases expression ISO Benztropine results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr16:37,330,158...37,360,151
Ensembl chr16:37,330,152...37,360,151
JBrowse link
G Gtf2f1 general transcription factor IIF, polypeptide 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GTF2F1 protein CTD PMID:34122009 NCBI chr17:57,310,402...57,318,398
Ensembl chr17:57,310,405...57,318,288
JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO Benztropine results in increased expression of GTPBP4 protein CTD PMID:34122009 NCBI chr13:9,016,039...9,046,080
Ensembl chr13:9,016,367...9,046,119
JBrowse link
G Gys1 glycogen synthase 1, muscle multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of GYS1 protein CTD PMID:34122009 NCBI chr 7:45,084,263...45,106,041
Ensembl chr 7:45,084,268...45,106,043
JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Benztropine results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 3:96,127,728...96,128,209
Ensembl chr 3:96,127,677...96,128,196
JBrowse link
G H2aj H2J.A histone increases expression ISO Benztropine results in increased expression of H2AJ protein CTD PMID:34122009 NCBI chr 6:136,785,246...136,787,072
Ensembl chr 6:136,785,242...136,787,072
JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression ISO Benztropine results in increased expression of HACD3 protein CTD PMID:34122009 NCBI chr 9:64,894,265...64,929,014
Ensembl chr 9:64,894,265...64,928,975
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Benztropine results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Benztropine results in increased expression of HARS1 protein CTD PMID:34122009 NCBI chr18:36,899,581...36,916,258
Ensembl chr18:36,899,581...36,916,258
JBrowse link
G Hat1 histone aminotransferase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HAT1 protein CTD PMID:34122009 NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:72,986,400...73,011,430
Ensembl chr  X:72,986,398...73,009,963
JBrowse link
G Hmcn2 hemicentin 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HMCN2 protein CTD PMID:34122009 NCBI chr 2:31,204,273...31,350,751
Ensembl chr 2:31,204,427...31,350,750
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Benztropine results in decreased expression of HNRNPD protein CTD PMID:34122009 NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157
JBrowse link
G Hps3 HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HPS3 protein CTD PMID:34122009 NCBI chr 3:20,050,109...20,089,478
Ensembl chr 3:20,050,109...20,089,479
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO Benztropine results in increased expression of HSD17B12 protein CTD PMID:34122009 NCBI chr 2:93,863,042...93,988,254
Ensembl chr 2:93,863,034...93,988,309
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of HSP90B1 protein CTD PMID:34122009 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase decreases expression ISO Benztropine results in decreased expression of IDI1 protein CTD PMID:34122009 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Benztropine results in decreased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Benztropine results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il24 interleukin 24 increases expression ISO Benztropine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Jam3 junction adhesion molecule 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of JAM3 protein CTD PMID:34122009 NCBI chr 9:27,008,680...27,066,739
Ensembl chr 9:27,008,680...27,066,717
JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of JPT2 protein CTD PMID:34122009 NCBI chr17:25,161,444...25,179,597
Ensembl chr17:25,156,393...25,179,663
JBrowse link
G Kars1 lysyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KARS1 protein CTD PMID:34122009 NCBI chr 8:112,720,071...112,737,986
Ensembl chr 8:112,720,075...112,737,955
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Benztropine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kctd12 potassium channel tetramerisation domain containing 12 decreases expression ISO Benztropine results in decreased expression of KCTD12 protein CTD PMID:34122009 NCBI chr14:103,214,017...103,220,073
Ensembl chr14:103,214,017...103,220,073
JBrowse link
G Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 decreases expression ISO Benztropine results in decreased expression of KHDRBS1 protein CTD PMID:34122009 NCBI chr 4:129,596,143...129,637,402
Ensembl chr 4:129,596,957...129,636,096
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Benztropine results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 2:49,509,298...49,664,790
Ensembl chr 2:49,509,310...49,664,790
JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr12:69,343,455...69,357,461
Ensembl chr12:69,343,455...69,357,461
JBrowse link
G Klhl41 kelch-like 41 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of KLHL41 protein CTD PMID:34122009 NCBI chr 2:69,500,464...69,514,583
Ensembl chr 2:69,500,464...69,514,574
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Benztropine results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 3:68,979,554...69,034,425
Ensembl chr 3:68,974,482...69,034,446
JBrowse link
G Ktn1 kinectin 1 decreases expression
multiple interactions
ISO Benztropine results in decreased expression of KTN1 protein
[Cuprizone co-treated with Benztropine] results in increased expression of KTN1 protein
CTD PMID:34122009 NCBI chr14:47,886,551...47,974,021
Ensembl chr14:47,885,905...47,977,351
JBrowse link
G Lactb2 lactamase, beta 2 increases expression ISO Benztropine results in increased expression of LACTB2 protein CTD PMID:34122009 NCBI chr 1:13,695,069...13,730,749
Ensembl chr 1:13,693,554...13,730,770
JBrowse link
G Lamb1 laminin B1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMB1 protein CTD PMID:34122009 NCBI chr12:31,315,230...31,379,643
Ensembl chr12:31,315,233...31,379,643
JBrowse link
G Lamc1 laminin, gamma 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LAMC1 protein CTD PMID:34122009 NCBI chr 1:153,094,668...153,208,532
Ensembl chr 1:153,094,668...153,208,532
JBrowse link
G Lima1 LIM domain and actin binding 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of LIMA1 protein CTD PMID:34122009 NCBI chr15:99,676,351...99,773,292
Ensembl chr15:99,676,351...99,773,337
JBrowse link
G Lipa lysosomal acid lipase A increases expression ISO Benztropine results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
JBrowse link
G Lmod2 leiomodin 2 (cardiac) increases expression ISO Benztropine results in increased expression of LMOD2 protein CTD PMID:34122009 NCBI chr 6:24,597,770...24,605,413
Ensembl chr 6:24,597,761...24,605,413
JBrowse link
G Lss lanosterol synthase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LSS protein CTD PMID:34122009 NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LTA4H protein CTD PMID:34122009 NCBI chr10:93,289,258...93,320,758
Ensembl chr10:93,289,273...93,320,737
JBrowse link
G Luc7l Luc7-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of LUC7L protein CTD PMID:34122009 NCBI chr17:26,471,874...26,504,484
Ensembl chr17:26,471,870...26,504,478
JBrowse link
G Magea1 MAGE family member A1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGEA9B protein CTD PMID:34122009 NCBI chr  X:153,871,515...153,872,786
Ensembl chr  X:153,871,682...153,872,789
JBrowse link
G Magea9 MAGE family member A9 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGEA9 protein CTD PMID:34122009 NCBI chr  X:63,217,154...63,222,385
Ensembl chr  X:63,217,154...63,222,384
JBrowse link
G Maged2 MAGE family member D2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MAGED2 protein CTD PMID:34122009 NCBI chr  X:149,589,417...149,597,358
Ensembl chr  X:149,589,366...149,597,341
JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO Benztropine results in increased expression of MAP1S protein CTD PMID:34122009 NCBI chr 8:71,358,618...71,370,173
Ensembl chr 8:71,358,576...71,370,173
JBrowse link
G Map4 microtubule-associated protein 4 decreases expression ISO Benztropine results in decreased expression of MAP4 protein CTD PMID:34122009 NCBI chr 9:109,758,909...109,913,018
Ensembl chr 9:109,760,528...109,913,023
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 decreases expression ISO Benztropine results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 2:153,583,131...153,615,237
Ensembl chr 2:153,583,194...153,615,230
JBrowse link
G Marcksl1 MARCKS-like 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MARCKSL1 protein CTD PMID:34122009 NCBI chr 4:129,407,374...129,409,774
Ensembl chr 4:129,407,374...129,409,778
JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit methionine multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MAT2B protein CTD PMID:34122009 NCBI chr11:40,570,141...40,586,030
Ensembl chr11:40,570,141...40,586,030
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 decreases expression ISO Benztropine results in decreased expression of MBOAT7 protein CTD PMID:34122009 NCBI chr 7:3,680,788...3,696,188
Ensembl chr 7:3,680,788...3,696,522
JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) decreases expression ISO Benztropine results in decreased expression of MDH1 protein CTD PMID:34122009 NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367
JBrowse link
G Met met proto-oncogene increases expression ISO Benztropine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Metap2 methionine aminopeptidase 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of METAP2 protein CTD PMID:34122009 NCBI chr10:93,694,351...93,732,952
Ensembl chr10:93,694,351...93,732,955
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) increases expression ISO Benztropine results in increased expression of MIF protein CTD PMID:34122009 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074
JBrowse link
G Mtdh metadherin multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of MTDH protein CTD PMID:34122009 NCBI chr15:34,082,613...34,143,683
Ensembl chr15:34,082,840...34,145,770
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of MTHFD1L protein CTD PMID:34122009 NCBI chr10:3,918,282...4,117,081
Ensembl chr10:3,923,118...4,117,081
JBrowse link
G Myh3 myosin, heavy polypeptide 3, skeletal muscle, embryonic increases expression ISO Benztropine results in increased expression of MYH3 protein CTD PMID:34122009 NCBI chr11:66,969,101...66,993,117
Ensembl chr11:66,969,126...66,993,112
JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO Benztropine results in decreased expression of NAT10 protein CTD PMID:34122009 NCBI chr 2:103,551,603...103,593,292
Ensembl chr 2:103,551,601...103,591,615
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 decreases expression ISO Benztropine results in decreased expression of NCBP1 protein CTD PMID:34122009 NCBI chr 4:46,138,732...46,172,403
Ensembl chr 4:46,138,613...46,172,403
JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Benztropine results in decreased expression of NECTIN2 protein CTD PMID:34122009 NCBI chr 7:19,450,569...19,483,498
Ensembl chr 7:19,450,569...19,484,408
JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Benztropine results in increased expression of NNMT protein CTD PMID:34122009 NCBI chr 9:48,448,905...48,518,958
Ensembl chr 9:48,503,177...48,516,453
JBrowse link
G Noc2l NOC2 like nucleolar associated transcriptional repressor increases expression ISO Benztropine results in increased expression of NOC2L protein CTD PMID:34122009 NCBI chr 4:156,319,112...156,332,078
Ensembl chr 4:156,320,376...156,332,073
JBrowse link
G Nsf N-ethylmaleimide sensitive fusion protein decreases expression ISO Benztropine results in decreased expression of NSF protein CTD PMID:34122009 NCBI chr11:103,712,608...103,844,882
Ensembl chr11:103,712,608...103,844,882
JBrowse link
G Nsfl1c NSFL1 (p97) cofactor (p47) decreases expression ISO Benztropine results in decreased expression of NSFL1C protein CTD PMID:34122009 NCBI chr 2:151,336,102...151,353,230
Ensembl chr 2:151,336,102...151,353,334
JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of NUMA1 protein CTD PMID:34122009 NCBI chr 7:101,583,169...101,664,166
Ensembl chr 7:101,583,318...101,664,171
JBrowse link
G Nup153 nucleoporin 153 increases expression ISO Benztropine results in increased expression of NUP153 protein CTD PMID:34122009 NCBI chr13:46,833,369...46,890,682
Ensembl chr13:46,833,381...46,881,416
JBrowse link
G Nup50 nucleoporin 50 increases expression ISO Benztropine results in increased expression of NUP50 protein CTD PMID:34122009 NCBI chr15:84,800,100...84,827,164
Ensembl chr15:84,807,612...84,827,164
JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Benztropine results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr 5:92,563,399...92,583,117
Ensembl chr 5:92,563,399...92,583,078
JBrowse link
G Nup93 nucleoporin 93 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NUP93 protein CTD PMID:34122009 NCBI chr 8:94,941,203...95,043,858
Ensembl chr 8:94,941,192...95,043,855
JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of NXF1 protein CTD PMID:34122009 NCBI chr19:8,734,467...8,748,274
Ensembl chr19:8,734,437...8,748,286
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) decreases expression ISO Benztropine results in decreased expression of OGDH protein CTD PMID:34122009 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642
JBrowse link
G Ola1 Obg-like ATPase 1 increases expression ISO Benztropine results in increased expression of OLA1 protein CTD PMID:34122009 NCBI chr 2:72,923,145...73,044,791
Ensembl chr 2:72,923,145...73,049,268
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide decreases expression ISO Benztropine results in decreased expression of P4HB protein CTD PMID:34122009 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PA2G4 protein CTD PMID:34122009 NCBI chr10:128,393,635...128,401,803
Ensembl chr10:128,393,635...128,401,856
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PAFAH1B1 protein CTD PMID:34122009 NCBI chr11:74,564,775...74,615,210
Ensembl chr11:74,564,775...74,615,496
JBrowse link
G Pag1 phosphoprotein associated with glycosphingolipid microdomains 1 decreases expression ISO Benztropine results in decreased expression of PAG1 protein CTD PMID:34122009 NCBI chr 3:9,752,539...9,898,744
Ensembl chr 3:9,752,539...9,898,739
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in increased expression of PARP1 protein
Benztropine results in decreased expression of PARP1 protein
CTD PMID:34122009 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pcbp1 poly(rC) binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PCBP1 protein CTD PMID:34122009 NCBI chr 6:86,501,462...86,503,171
Ensembl chr 6:86,501,474...86,503,303
JBrowse link
G Pcbp2 poly(rC) binding protein 2 decreases expression ISO Benztropine results in decreased expression of PCBP2 protein CTD PMID:34122009 NCBI chr15:102,378,974...102,408,503
Ensembl chr15:102,378,974...102,408,496
JBrowse link
G Pcdhga2 protocadherin gamma subfamily A, 2 decreases expression ISO Benztropine results in decreased expression of PCDHGA2 protein CTD PMID:34122009 NCBI chr18:37,801,980...37,974,923
Ensembl chr18:37,802,006...37,974,923
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr10:7,503,608...7,556,922
Ensembl chr10:7,505,137...7,556,900
JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein increases expression ISO Benztropine results in increased expression of PCNP protein CTD PMID:34122009 NCBI chr16:55,835,870...55,851,590
Ensembl chr16:55,827,608...55,850,102
JBrowse link
G Pcx pyruvate carboxylase multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PC protein CTD PMID:34122009 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
JBrowse link
G Pdcl3 phosducin-like 3 decreases expression ISO Benztropine results in decreased expression of PDCL3 protein CTD PMID:34122009 NCBI chr 1:39,026,895...39,036,317
Ensembl chr 1:39,024,689...39,036,319
JBrowse link
G Pdia3 protein disulfide isomerase associated 3 decreases expression ISO Benztropine results in decreased expression of PDIA3 protein CTD PMID:34122009 NCBI chr 2:121,244,383...121,269,168
Ensembl chr 2:121,244,256...121,269,168
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PDIA6 protein CTD PMID:34122009 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Benztropine results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 3:141,945,346...142,101,480
Ensembl chr 3:141,945,351...142,101,454
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Benztropine results in decreased expression of PEBP1 protein CTD PMID:34122009 NCBI chr 5:117,420,716...117,425,629
Ensembl chr 5:117,420,719...117,425,690
JBrowse link
G Pfn1 profilin 1 increases expression ISO Benztropine results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470
JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Benztropine results in decreased expression of PGK1 protein CTD PMID:34122009 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305
JBrowse link
G Pgm3 phosphoglucomutase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PGM3 protein CTD PMID:34122009 NCBI chr 9:86,423,997...86,453,927
Ensembl chr 9:86,436,430...86,453,895
JBrowse link
G Phf14 PHD finger protein 14 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PHF14 protein CTD PMID:34122009 NCBI chr 6:11,907,728...12,100,155
Ensembl chr 6:11,907,808...12,081,204
JBrowse link
G Phgdh 3-phosphoglycerate dehydrogenase decreases expression ISO Benztropine results in decreased expression of PHGDH protein CTD PMID:34122009 NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Benztropine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Pin1 peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PIN1 protein CTD PMID:34122009 NCBI chr 9:20,563,335...20,575,008
Ensembl chr 9:20,563,391...20,577,880
JBrowse link
G Pmpca peptidase (mitochondrial processing) alpha increases expression ISO Benztropine results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 2:26,275,554...26,287,134
Ensembl chr 2:26,279,351...26,287,134
JBrowse link
G Pnma1 paraneoplastic antigen MA1 increases expression ISO Benztropine results in increased expression of PNMA1 protein CTD PMID:34122009 NCBI chr12:84,192,905...84,195,263
Ensembl chr12:84,192,905...84,195,263
JBrowse link
G Pnma8a PNMA family member 8A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PNMA8A protein CTD PMID:34122009 NCBI chr 7:16,683,325...16,698,532
Ensembl chr 7:16,693,604...16,698,532
JBrowse link
G Pon3 paraoxonase 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PON3 protein CTD PMID:34122009 NCBI chr 6:5,216,253...5,256,236
Ensembl chr 6:5,220,852...5,256,286
JBrowse link
G Ppa1 pyrophosphatase (inorganic) 1 increases expression
multiple interactions
ISO Benztropine results in increased expression of PPA1 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of PPA1 protein
CTD PMID:34122009 NCBI chr10:61,484,400...61,509,944
Ensembl chr10:61,484,331...61,509,947
JBrowse link
G Ppm1f protein phosphatase 1F (PP2C domain containing) decreases expression ISO Benztropine results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr16:16,714,314...16,745,239
Ensembl chr16:16,714,333...16,745,228
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PPP1R12A protein CTD PMID:34122009 NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr19:6,952,416...6,954,692
Ensembl chr19:6,952,336...6,954,692
JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform increases expression ISO Benztropine results in increased expression of PPP3CA protein CTD PMID:34122009 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488
JBrowse link
G Prkar2a protein kinase, cAMP dependent regulatory, type II alpha multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRKAR2A protein CTD PMID:34122009 NCBI chr 9:108,569,342...108,627,643
Ensembl chr 9:108,566,513...108,627,635
JBrowse link
G Prkcsh protein kinase C substrate 80K-H multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 9:21,914,314...21,925,521
Ensembl chr 9:21,914,102...21,925,518
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 decreases expression ISO Benztropine results in decreased expression of PRMT1 protein CTD PMID:34122009 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Prpf6 pre-mRNA splicing factor 6 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of PRPF6 protein CTD PMID:34122009 NCBI chr 2:181,243,112...181,297,454
Ensembl chr 2:181,233,661...181,297,453
JBrowse link
G Psma1 proteasome subunit alpha 1 decreases expression ISO Benztropine results in decreased expression of PSMA1 protein CTD PMID:34122009 NCBI chr 7:113,863,785...113,875,351
Ensembl chr 7:113,863,841...113,875,353
JBrowse link
G Psmb7 proteasome (prosome, macropain) subunit, beta type 7 decreases expression ISO Benztropine results in decreased expression of PSMB7 protein CTD PMID:34122009 NCBI chr 2:38,478,058...38,533,964
Ensembl chr 2:38,478,048...38,534,099
JBrowse link
G Psmc1 protease (prosome, macropain) 26S subunit, ATPase 1 decreases expression ISO Benztropine results in decreased expression of PSMC1 protein CTD PMID:34122009 NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664
JBrowse link
G Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 increases expression ISO Benztropine results in increased expression of PSMC3 protein CTD PMID:34122009 NCBI chr 2:90,884,361...90,889,783
Ensembl chr 2:90,884,354...90,896,714
JBrowse link
G Psmd7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 increases expression ISO Benztropine results in increased expression of PSMD7 protein CTD PMID:34122009 NCBI chr 8:108,307,012...108,315,114
Ensembl chr 8:108,307,013...108,315,096
JBrowse link
G Ptcd3 pentatricopeptide repeat domain 3 increases expression
multiple interactions
ISO Benztropine results in increased expression of PTCD3 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of PTCD3 protein
CTD PMID:34122009 NCBI chr 6:71,857,622...71,886,080
Ensembl chr 6:71,857,622...71,885,734
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Benztropine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptk7 PTK7 protein tyrosine kinase 7 decreases expression ISO Benztropine results in decreased expression of PTK7 protein CTD PMID:34122009 NCBI chr17:46,875,377...46,940,975
Ensembl chr17:46,875,397...46,940,430
JBrowse link
G Puf60 poly-U binding splicing factor 60 decreases expression ISO Benztropine results in decreased expression of PUF60 protein CTD PMID:34122009 NCBI chr15:75,942,031...75,954,386
Ensembl chr15:75,942,031...75,952,773
JBrowse link
G Pwp2 PWP2 periodic tryptophan protein homolog (yeast) increases expression ISO Benztropine results in increased expression of PWP2 protein CTD PMID:34122009 NCBI chr10:78,006,743...78,021,005
Ensembl chr10:78,006,743...78,020,983
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Benztropine results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr11:120,527,591...120,534,602
Ensembl chr11:120,526,538...120,534,595
JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Benztropine results in decreased expression of QDPR protein CTD PMID:34122009 NCBI chr 5:45,591,374...45,607,571
Ensembl chr 5:45,591,363...45,607,578
JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Benztropine results in decreased expression of RACK1 protein CTD PMID:34122009 NCBI chr11:48,691,187...48,697,068
Ensembl chr11:48,691,159...48,697,261
JBrowse link
G Rbm15 RNA binding motif protein 15 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RBM15 protein CTD PMID:34122009 NCBI chr 3:107,212,827...107,244,102
Ensembl chr 3:107,232,737...107,240,989
JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of RIC8A protein CTD PMID:34122009 NCBI chr 7:140,437,310...140,443,644
Ensembl chr 7:140,436,870...140,444,285
JBrowse link
G Rpl10a ribosomal protein L10A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL10A protein CTD PMID:34122009 NCBI chr17:28,547,557...28,550,007
Ensembl chr17:28,547,445...28,550,007
JBrowse link
G Rpl19 ribosomal protein L19 increases expression ISO Benztropine results in increased expression of RPL19 protein CTD PMID:34122009 NCBI chr11:97,912,829...97,921,319
Ensembl chr11:97,917,536...97,921,318
JBrowse link
G Rpl24 ribosomal protein L24 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPL24 protein CTD PMID:34122009 NCBI chr16:55,786,638...55,791,800
Ensembl chr16:55,786,638...55,791,798
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Benztropine results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr15:34,440,649...34,443,405
Ensembl chr15:34,440,651...34,443,786
JBrowse link
G Rpl7a ribosomal protein L7A decreases expression ISO Benztropine results in decreased expression of RPL7A protein CTD PMID:34122009 NCBI chr 2:26,800,697...26,803,330
Ensembl chr 2:26,800,776...26,803,330
JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPLP1 protein CTD PMID:34122009 NCBI chr 9:61,820,565...61,821,792
Ensembl chr 9:61,820,566...61,821,824
JBrowse link
G Rps12 ribosomal protein S12 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS12 protein CTD PMID:34122009 NCBI chr10:23,661,042...23,664,297
Ensembl chr10:23,661,081...23,663,173
JBrowse link
G Rps18 ribosomal protein S18 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of RPS18 protein CTD PMID:34122009 NCBI chr17:34,170,972...34,174,639
Ensembl chr17:34,170,973...34,174,975
JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Benztropine results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 3:90,119,974...90,120,955
Ensembl chr 3:90,119,829...90,120,958
JBrowse link
G Rps27a ribosomal protein S27A increases expression ISO Benztropine results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr11:29,495,842...29,498,040
Ensembl chr11:29,495,846...29,498,109
JBrowse link
G Rps3 ribosomal protein S3 decreases expression ISO Benztropine results in decreased expression of RPS3 protein CTD PMID:34122009 NCBI chr 7:99,127,103...99,132,916
Ensembl chr 7:99,127,103...99,132,945
JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 increases expression ISO Benztropine results in increased expression of RUVBL2 protein CTD PMID:34122009 NCBI chr 7:45,071,320...45,084,817
Ensembl chr 7:45,071,184...45,087,520
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SAE1 protein CTD PMID:34122009 NCBI chr 7:16,054,161...16,121,821
Ensembl chr 7:16,054,159...16,121,731
JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Benztropine results in decreased expression of SARS1 protein CTD PMID:34122009 NCBI chr 3:108,332,180...108,352,575
Ensembl chr 3:108,332,181...108,352,525
JBrowse link
G Satb2 special AT-rich sequence binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SATB2 protein CTD PMID:34122009 NCBI chr 1:56,833,145...57,019,350
Ensembl chr 1:56,833,140...57,017,809
JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression ISO Benztropine results in decreased expression of SCCPDH protein CTD PMID:34122009 NCBI chr 1:179,495,796...179,514,754
Ensembl chr 1:179,495,775...179,514,754
JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Benztropine results in decreased expression of SDCBP protein CTD PMID:34122009 NCBI chr 4:6,365,713...6,396,120
Ensembl chr 4:6,365,650...6,408,423
JBrowse link
G Sec23a SEC23 homolog A, COPII coat complex component multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SEC23A protein CTD PMID:34122009 NCBI chr12:59,005,170...59,058,803
Ensembl chr12:59,005,169...59,058,803
JBrowse link
G Sec61b SEC61 translocon subunit beta increases expression ISO Benztropine results in increased expression of SEC61B protein CTD PMID:34122009 NCBI chr 4:47,474,661...47,483,233
Ensembl chr 4:47,474,658...47,483,242
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Benztropine results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr10:42,637,492...42,708,510
Ensembl chr10:42,637,492...42,708,510
JBrowse link
G Serbp1 serpine1 mRNA binding protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SERBP1 protein CTD PMID:34122009 NCBI chr 6:67,243,963...67,266,286
Ensembl chr 6:67,215,160...67,274,720
JBrowse link
G Serpinb3a serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A increases expression ISO Benztropine results in increased expression of SERPINB4 protein CTD PMID:34122009 NCBI chr 1:106,973,317...106,980,033
Ensembl chr 1:106,973,317...106,980,033
JBrowse link
G Sf1 splicing factor 1 decreases expression ISO Benztropine results in decreased expression of SF1 protein CTD PMID:34122009 NCBI chr19:6,413,952...6,428,060
Ensembl chr19:6,413,720...6,428,060
JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 decreases expression ISO Benztropine results in decreased expression of SF3B3 protein CTD PMID:34122009 NCBI chr 8:111,537,123...111,573,578
Ensembl chr 8:111,536,871...111,573,419
JBrowse link
G Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) decreases expression ISO Benztropine results in decreased expression of SGCA protein CTD PMID:34122009 NCBI chr11:94,853,603...94,867,153
Ensembl chr11:94,853,617...94,867,153
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr11:32,297,777...32,378,189
Ensembl chr11:32,297,820...32,378,173
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 (soluble) multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SHMT1 protein CTD PMID:34122009 NCBI chr11:60,679,723...60,702,062
Ensembl chr11:60,678,930...60,702,544
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Benztropine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 decreases expression ISO Benztropine results in decreased expression of SLC2A1 protein CTD PMID:34122009 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
JBrowse link
G Slc38a2 solute carrier family 38, member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC38A2 protein CTD PMID:34122009 NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of SLC3A2 protein CTD PMID:34122009 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 multiple interactions ISO Benztropine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine] CTD PMID:17250655 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Benztropine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 decreases expression ISO Benztropine results in decreased expression of SMARCB1 protein CTD PMID:34122009 NCBI chr10:75,732,603...75,757,448
Ensembl chr10:75,732,603...75,757,451
JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMC3 protein CTD PMID:34122009 NCBI chr19:53,588,827...53,634,262
Ensembl chr19:53,588,829...53,634,264
JBrowse link
G Smu1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SMU1 protein CTD PMID:34122009 NCBI chr 4:40,735,649...40,757,885
Ensembl chr 4:40,736,542...40,757,923
JBrowse link
G Snrnp200 small nuclear ribonucleoprotein 200 (U5) increases expression
multiple interactions
ISO Benztropine results in increased expression of SNRNP200 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of SNRNP200 protein
CTD PMID:34122009 NCBI chr 2:127,050,306...127,082,373
Ensembl chr 2:127,050,306...127,082,371
JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Benztropine results in increased expression of SNRPA protein CTD PMID:34122009 NCBI chr 7:26,886,431...26,895,696
Ensembl chr 7:26,886,430...26,895,696
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 increases expression ISO Benztropine results in increased expression of SNRPD2 protein CTD PMID:34122009 NCBI chr 7:18,883,370...18,886,659
Ensembl chr 7:18,883,647...18,887,467
JBrowse link
G Srek1 splicing regulatory glutamine/lysine-rich protein 1 decreases expression ISO Benztropine results in decreased expression of SREK1 protein CTD PMID:34122009 NCBI chr13:103,873,291...103,911,379
Ensembl chr13:103,875,856...103,911,116
JBrowse link
G Srsf5 serine and arginine-rich splicing factor 5 increases expression ISO Benztropine results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr12:80,992,308...80,997,277
Ensembl chr12:80,992,278...80,997,281
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of STAT3 protein CTD PMID:34122009 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stim1 stromal interaction molecule 1 decreases expression ISO Benztropine results in decreased expression of STIM1 protein CTD PMID:34122009 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Benztropine results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335
JBrowse link
G Strap serine/threonine kinase receptor associated protein decreases expression ISO Benztropine results in decreased expression of STRAP protein CTD PMID:34122009 NCBI chr 6:137,712,080...137,728,928
Ensembl chr 6:137,712,076...137,728,930
JBrowse link
G Stub1 STIP1 homology and U-Box containing protein 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of STUB1 protein CTD PMID:34122009 NCBI chr17:26,049,608...26,051,893
Ensembl chr17:26,049,479...26,052,378
JBrowse link
G Suclg1 succinate-CoA ligase, GDP-forming, alpha subunit decreases expression ISO Benztropine results in decreased expression of SUCLG1 protein CTD PMID:34122009 NCBI chr 6:73,225,488...73,253,890
Ensembl chr 6:73,225,365...73,253,894
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 decreases expression ISO Benztropine results in decreased expression of SUMO2 protein CTD PMID:34122009 NCBI chr11:115,413,935...115,427,056
Ensembl chr11:115,413,928...115,427,102
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of SUN1 protein CTD PMID:34122009 NCBI chr 5:139,186,313...139,235,594
Ensembl chr 5:139,186,392...139,235,595
JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO Benztropine results in decreased expression of SYNCRIP protein CTD PMID:34122009 NCBI chr 9:88,331,417...88,364,645
Ensembl chr 9:88,329,062...88,364,627
JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Benztropine results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr 1:172,327,813...172,334,942
Ensembl chr 1:172,327,614...172,334,947
JBrowse link
G Tbcb tubulin folding cofactor B decreases expression ISO Benztropine results in decreased expression of TBCB protein CTD PMID:34122009 NCBI chr 7:29,923,554...29,931,622
Ensembl chr 7:29,923,556...29,931,697
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TCAF1 protein
Benztropine results in decreased expression of TCAF1 protein
CTD PMID:34122009 NCBI chr 6:42,644,933...42,687,065
Ensembl chr 6:42,644,936...42,687,022
JBrowse link
G Tgoln1 trans-golgi network protein multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 6:72,585,403...72,593,983
Ensembl chr 6:72,585,415...72,593,983
JBrowse link
G Tln2 talin 2 decreases expression ISO Benztropine results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 9:67,124,371...67,541,357
Ensembl chr 9:67,124,369...67,466,985
JBrowse link
G Tmpo thymopoietin decreases expression ISO Benztropine results in decreased expression of TMPO protein CTD PMID:34122009 NCBI chr10:90,983,433...91,017,614
Ensembl chr10:90,983,433...91,017,177
JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 decreases expression
multiple interactions
ISO Benztropine results in decreased expression of TNKS1BP1 protein
[Cuprizone co-treated with Benztropine] results in decreased expression of TNKS1BP1 protein
CTD PMID:34122009 NCBI chr 2:84,878,356...84,903,392
Ensembl chr 2:84,878,366...84,903,392
JBrowse link
G Tomm34 translocase of outer mitochondrial membrane 34 decreases expression
multiple interactions
ISO Benztropine results in decreased expression of TOMM34 protein
[Cuprizone co-treated with Benztropine] results in increased expression of TOMM34 protein
CTD PMID:34122009 NCBI chr 2:163,895,458...163,913,168
Ensembl chr 2:163,895,460...163,913,089
JBrowse link
G Top1mt DNA topoisomerase 1, mitochondrial increases expression ISO Benztropine results in increased expression of TOP1MT protein CTD PMID:34122009 NCBI chr15:75,528,878...75,551,184
Ensembl chr15:75,528,884...75,550,649
JBrowse link
G Tpm2 tropomyosin 2, beta decreases expression ISO Benztropine results in decreased expression of TPM2 protein CTD PMID:34122009 NCBI chr 4:43,513,726...43,523,583
Ensembl chr 4:43,514,711...43,523,765
JBrowse link
G Tpm3 tropomyosin 3, gamma decreases expression ISO Benztropine results in decreased expression of TPM3 protein CTD PMID:34122009 NCBI chr 3:89,979,958...90,008,209
Ensembl chr 3:89,979,956...90,008,209
JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO Benztropine results in decreased expression of TPR protein CTD PMID:34122009 NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686
JBrowse link
G Trim28 tripartite motif-containing 28 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Benztropine] results in increased expression of TRIM28 protein
Benztropine results in decreased expression of TRIM28 protein
CTD PMID:34122009 NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962
JBrowse link
G Tspan3 tetraspanin 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TSPAN3 protein CTD PMID:34122009 NCBI chr 9:56,043,168...56,068,354
Ensembl chr 9:56,039,009...56,072,761
JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of TTC21A protein CTD PMID:34122009 NCBI chr 9:119,766,656...119,798,496
Ensembl chr 9:119,766,672...119,796,859
JBrowse link
G Ttyh2 tweety family member 2 increases expression ISO Benztropine results in increased expression of TTYH2 protein CTD PMID:34122009 NCBI chr11:114,566,294...114,611,810
Ensembl chr11:114,566,257...114,611,803
JBrowse link
G Ttyh3 tweety family member 3 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TTYH3 protein CTD PMID:34122009 NCBI chr 5:140,606,332...140,634,826
Ensembl chr 5:140,606,333...140,634,786
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Benztropine results in increased expression of TUBB protein CTD PMID:34122009 NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198
JBrowse link
G Twf2 twinfilin actin binding protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of TWF2 protein CTD PMID:34122009 NCBI chr 9:106,080,307...106,092,586
Ensembl chr 9:106,080,307...106,092,588
JBrowse link
G Txlna taxilin alpha decreases expression ISO Benztropine results in decreased expression of TXLNA protein CTD PMID:34122009 NCBI chr 4:129,519,870...129,534,867
Ensembl chr 4:129,519,871...129,534,858
JBrowse link
G Tyms thymidylate synthase increases expression ISO Benztropine results in increased expression of TYMS protein CTD PMID:34122009 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
JBrowse link
G U2af2 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 decreases expression ISO Benztropine results in decreased expression of U2AF2 protein CTD PMID:34122009 NCBI chr 7:5,063,884...5,082,937
Ensembl chr 7:5,065,142...5,082,937
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UBA2 protein CTD PMID:34122009 NCBI chr 7:33,840,121...33,868,014
Ensembl chr 7:33,840,113...33,869,024
JBrowse link
G Ubap2l ubiquitin-associated protein 2-like decreases expression ISO Benztropine results in decreased expression of UBAP2L protein CTD PMID:34122009 NCBI chr 3:89,906,896...89,959,867
Ensembl chr 3:89,907,447...89,959,935
JBrowse link
G Ubc ubiquitin C increases expression ISO Benztropine results in increased expression of UBC protein CTD PMID:34122009 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266
JBrowse link
G Ubqln2 ubiquilin 2 decreases expression ISO Benztropine results in decreased expression of UBQLN2 protein CTD PMID:34122009 NCBI chr  X:152,281,228...152,284,558
Ensembl chr  X:152,281,223...152,284,566
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UCHL1 protein CTD PMID:34122009 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
JBrowse link
G Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) decreases expression ISO Benztropine results in decreased expression of UCHL3 protein CTD PMID:34122009 NCBI chr14:101,891,387...101,933,561
Ensembl chr14:101,891,403...101,933,561
JBrowse link
G Ugdh UDP-glucose dehydrogenase decreases expression ISO Benztropine results in decreased expression of UGDH protein CTD PMID:34122009 NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292
JBrowse link
G Unc45b unc-45 myosin chaperone B multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of UNC45B protein CTD PMID:34122009 NCBI chr11:82,802,112...82,834,284
Ensembl chr11:82,801,376...82,834,229
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of UQCRC2 protein CTD PMID:34122009 NCBI chr 7:120,234,412...120,258,746
Ensembl chr 7:120,234,399...120,258,747
JBrowse link
G Uso1 USO1 vesicle docking factor decreases expression ISO Benztropine results in decreased expression of USO1 protein CTD PMID:34122009 NCBI chr 5:92,285,770...92,350,659
Ensembl chr 5:92,285,797...92,350,657
JBrowse link
G Usp10 ubiquitin specific peptidase 10 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of USP10 protein CTD PMID:34122009 NCBI chr 8:120,637,099...120,684,299
Ensembl chr 8:120,637,099...120,684,299
JBrowse link
G Usp14 ubiquitin specific peptidase 14 increases expression ISO Benztropine results in increased expression of USP14 protein CTD PMID:34122009 NCBI chr18:9,993,615...10,030,149
Ensembl chr18:9,993,066...10,045,119
JBrowse link
G Utp18 UTP18 small subunit processome component increases expression ISO Benztropine results in increased expression of UTP18 protein CTD PMID:34122009 NCBI chr11:93,750,069...93,776,592
Ensembl chr11:93,750,069...93,776,592
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression ISO Benztropine results in decreased expression of VASP protein CTD PMID:34122009 NCBI chr 7:18,990,854...19,005,779
Ensembl chr 7:18,990,854...19,005,742
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase1 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr12:108,825,956...108,860,095
Ensembl chr12:108,825,956...108,860,100
JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Benztropine results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 1:60,110,520...60,137,659
Ensembl chr 1:60,108,944...60,137,804
JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Benztropine results in decreased expression of XIRP2 protein CTD PMID:34122009 NCBI chr 2:67,276,343...67,356,964
Ensembl chr 2:67,004,178...67,356,959
JBrowse link
G Xpo7 exportin 7 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in increased expression of XPO7 protein CTD PMID:34122009 NCBI chr14:70,899,566...71,004,075
Ensembl chr14:70,891,686...71,004,068
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta increases expression ISO Benztropine results in increased expression of YWHAQ protein CTD PMID:34122009 NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638
JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 multiple interactions ISO [Cuprizone co-treated with Benztropine] results in decreased expression of ZBTB42 protein CTD PMID:34122009 NCBI chr12:112,645,042...112,649,181
Ensembl chr12:112,645,262...112,649,181
JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Benztropine results in decreased expression of ZFR protein CTD PMID:34122009 NCBI chr15:12,117,649...12,185,535
Ensembl chr15:12,117,917...12,185,769
JBrowse link
G Zkscan7 zinc finger with KRAB and SCAN domains 7 decreases expression ISO Benztropine results in decreased expression of ZKSCAN7 protein CTD PMID:34122009 NCBI chr 9:122,715,883...122,727,684
Ensembl chr 9:122,714,750...122,727,683
JBrowse link
biperiden term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases activity ISO Biperiden results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Biperiden results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions ISO Biperiden binds to and results in decreased activity of CHRM1 protein CTD PMID:21336581 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO Biperiden results in increased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Ereg epiregulin increases expression ISO Biperiden results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Biperiden results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Biperiden results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il24 interleukin 24 increases expression ISO Biperiden results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Met met proto-oncogene increases expression ISO Biperiden results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Biperiden results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Biperiden results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
bromocriptine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A increases expression
multiple interactions
ISO Bromocriptine results in increased expression of ABCB1 protein
Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]; Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]
CTD PMID:9111066 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases activity
increases expression
multiple interactions
ISO Bromocriptine results in increased activity of ABCB1B promoter
Bromocriptine results in increased expression of ABCB1B mRNA
Clozapine inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; eticlopride inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Pertussis Toxin inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Spiperone inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]
CTD PMID:9111066 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 increases expression
multiple interactions
ISO Bromocriptine results in increased expression of AKR1C3 mRNA
methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA]
CTD PMID:21427058 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Bromocriptine results in increased expression of ATF3 mRNA; Bromocriptine results in increased expression of ATF3 protein CTD PMID:21867702 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Bax BCL2-associated X protein increases expression
multiple interactions
ISO Bromocriptine results in increased expression of BAX protein
[Bromocriptine co-treated with Octreotide] results in increased expression of BAX protein
CTD PMID:15046398 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bdnf brain derived neurotrophic factor decreases secretion EXP Bromocriptine results in decreased secretion of BDNF protein CTD PMID:12770616 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP [Bromocriptine co-treated with Estradiol] results in decreased expression of CTNNB1 protein CTD PMID:11786374 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of CYP11A1 mRNA]
Bromocriptine results in decreased expression of CYP11A1 protein
CTD PMID:12742521 PMID:21427058 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Bromocriptine results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Bromocriptine results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Dbh dopamine beta hydroxylase decreases activity ISO Bromocriptine results in decreased activity of DBH protein CTD PMID:501350 NCBI chr 2:27,055,519...27,073,216
Ensembl chr 2:27,055,245...27,073,212
JBrowse link
G Drd2 dopamine receptor D2 affects expression
affects response to substance
multiple interactions
decreases expression
increases expression
increases response to substance
ISO
EXP
Bromocriptine affects the expression of DRD2 mRNA
DRD2 protein affects the susceptibility to Bromocriptine
Bromocriptine binds to and results in increased activity of DRD2 mRNA; Bromocriptine promotes the reaction [Clozapine results in decreased expression of DRD2 mRNA]
Bromocriptine results in decreased expression of DRD2 mRNA
[Clozapine co-treated with Bromocriptine] results in decreased expression of DRD2 mRNA
Bromocriptine results in increased expression of DRD2 mRNA
DRD2 polymorphism results in increased susceptibility to Bromocriptine
CTD PMID:1534540 PMID:8103596 PMID:15781964 PMID:16901644 PMID:20063113 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions
decreases expression
ISO [1-Methyl-4-phenylpyridinium co-treated with Bromocriptine] results in decreased expression of DRD3 mRNA
Bromocriptine results in decreased expression of DRD3 mRNA
CTD PMID:17000468 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions EXP [Bromocriptine co-treated with Estradiol] results in increased expression of ESR1 protein CTD PMID:11786374 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Fshb follicle stimulating hormone beta increases expression ISO Bromocriptine results in increased expression of FSHB protein CTD PMID:86031 NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001
JBrowse link
G Gdnf glial cell line derived neurotrophic factor decreases expression
decreases secretion
EXP Bromocriptine results in decreased expression of GDNF mRNA
Bromocriptine results in decreased secretion of GDNF protein
CTD PMID:12770616 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Gh growth hormone increases expression
decreases expression
ISO Bromocriptine results in increased expression of GH1 protein
Bromocriptine results in decreased expression of GH1 protein
CTD PMID:772175 PMID:3226523 PMID:3745407 PMID:7293648 PMID:19420816 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Bromocriptine results in increased expression of HMOX1 mRNA; Bromocriptine results in increased expression of HMOX1 protein CTD PMID:21867702 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 multiple interactions ISO [Bromocriptine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Bromocriptine binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 NCBI chr19:35,935,815...36,035,533
Ensembl chr19:35,936,134...36,034,907
JBrowse link
G Ins2 insulin II decreases expression ISO Bromocriptine results in decreased expression of INS protein CTD PMID:16803851 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Lhb luteinizing hormone beta increases expression ISO Bromocriptine results in increased expression of LHB protein CTD PMID:86031 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Bromocriptine promotes the reaction [Estrogens results in increased phosphorylation of and affects the localization of MAPK1 protein] CTD PMID:19595700 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Bromocriptine promotes the reaction [Estrogens results in increased phosphorylation of and affects the localization of MAPK3 protein] CTD PMID:19595700 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases localization ISO Bromocriptine results in increased localization of NFE2L2 protein CTD PMID:21867702 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Ngf nerve growth factor increases secretion EXP Bromocriptine results in increased secretion of NGF protein CTD PMID:12770616 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of NOS2 protein] CTD PMID:21867702 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions ISO Bromocriptine affects the reaction [methyl cellosolve results in increased expression of NR5A2 mRNA] CTD PMID:21427058 NCBI chr 1:136,770,300...136,888,186
Ensembl chr 1:136,770,309...136,888,186
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of PCNA protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PCNA protein] CTD PMID:15677882 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression
increases expression
multiple interactions
ISO Bromocriptine results in decreased expression of POMC protein alternative form
Bromocriptine results in increased expression of POMC mRNA; Bromocriptine results in increased expression of POMC protein modified form
Bromocriptine inhibits the reaction [POMC protein results in decreased secretion of Corticosterone]
CTD PMID:1325994 PMID:6274577 PMID:12742521 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Prkcd protein kinase C, delta multiple interactions
affects localization
ISO Bromocriptine promotes the reaction [Estrogens results in increased expression of and results in increased cleavage of PRKCD protein]
Bromocriptine affects the localization of PRKCD protein
CTD PMID:19595700 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Prl prolactin multiple interactions
decreases secretion
decreases expression
ISO
EXP
Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Nalorphine results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein]
Bromocriptine results in decreased secretion of PRL protein
Bromocriptine results in decreased expression of PRL protein
Bromocriptine inhibits the reaction [Amisulpride results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; Bromocriptine inhibits the reaction [Estradiol results in increased expression of PRL protein]; Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of PRL protein]; Estradiol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Ethanol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]
CTD PMID:86031 PMID:86795 PMID:90217 PMID:1407345 PMID:1874184 More... NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of SCARB1 mRNA] CTD PMID:21427058 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions EXP Bromocriptine inhibits the reaction [[SOD1 protein mutant form co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of NOS2 protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of TNF protein] CTD PMID:21867702 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO Bromocriptine results in decreased expression of STAR protein CTD PMID:12742521 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Stat5a signal transducer and activator of transcription 5A affects localization EXP Bromocriptine affects the localization of STAT5A protein CTD PMID:17884938 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO Bromocriptine inhibits the reaction [Estradiol results in increased expression of TGFA mRNA] CTD PMID:1534540 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of TGFB1 protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in decreased expression of TGFB1 protein] CTD PMID:15677882 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Bromocriptine inhibits the reaction [[SOD1 protein mutant form co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Bromocriptine inhibits the reaction [SOD1 mutant form results in increased expression of TNF protein]
Bromocriptine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:11752888 PMID:21867702 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VEGFA protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in decreased expression of VEGFA protein] CTD PMID:15677882 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vip vasoactive intestinal polypeptide multiple interactions ISO Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein]
[Bromocriptine co-treated with vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)-] inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP mRNA]; Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of VIP protein]
CTD PMID:6441721 PMID:15677882 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617
JBrowse link
cabergoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor increases expression ISO Cabergoline results in increased expression of BDNF protein CTD PMID:35104500 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO Cabergoline results in increased expression of CREB1 protein modified form CTD PMID:35104500 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO Cabergoline binds to and results in increased activity of DRD2 protein CTD PMID:35104500 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Gdnf glial cell line derived neurotrophic factor increases expression
increases secretion
EXP cabergoline results in increased expression of GDNF mRNA
cabergoline results in increased secretion of GDNF protein
CTD PMID:12770616 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Ngf nerve growth factor increases expression
increases secretion
EXP cabergoline results in increased expression of NGF mRNA
cabergoline results in increased secretion of NGF protein
CTD PMID:12770616 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Prl prolactin decreases expression
multiple interactions
decreases secretion
ISO cabergoline results in decreased expression of PRL protein
Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [cabergoline results in decreased secretion of PRL protein]
CTD PMID:2570719 PMID:3745407 PMID:7670571 PMID:15377706 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
carbidopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein multiple interactions ISO
EXP
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Carbidopa inhibits the reaction [Cisplatin results in increased expression of BAX protein]
Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of BAX protein]]
CTD PMID:34560070 PMID:35202708 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions EXP
ISO
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of BCL2 protein]]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Carbidopa inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]
CTD PMID:34560070 PMID:35202708 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP3 protein]]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]
CTD PMID:34560070 PMID:35202708 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 multiple interactions ISO
EXP
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased cleavage of CASP9 protein]]
CTD PMID:34560070 PMID:35202708 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Comt catechol-O-methyltransferase increases methylation ISO COMT protein results in increased methylation of Carbidopa CTD PMID:11160877 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Ddc dopa decarboxylase multiple interactions EXP
ISO
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of DDC mRNA]
Carbidopa binds to and results in decreased activity of DDC protein
CTD PMID:35151785 PMID:35202708 NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
JBrowse link
G Dnm1l dynamin 1-like multiple interactions EXP Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of DNM1L protein]] CTD PMID:35202708 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Fis1 fission, mitochondrial 1 multiple interactions EXP Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of FIS1 protein]] CTD PMID:35202708 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]] CTD PMID:35202708 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased secretion of IL1B protein]; Carbidopa inhibits the reaction [Cisplatin results in increased secretion of IL1B protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of IL1B protein]
CTD PMID:34560070 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Maoa monoamine oxidase A multiple interactions EXP
ISO
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of MAOA protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA mRNA]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]; Carbidopa inhibits the reaction [Cisplatin results in increased expression of MAOA protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in increased expression of MAOA protein]] CTD PMID:34560070 PMID:35202708 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057
JBrowse link
G Mfn1 mitofusin 1 multiple interactions EXP [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of MFN1 protein]] CTD PMID:35202708 NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388
JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial multiple interactions EXP Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ATP6 protein]] CTD PMID:35202708 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607
JBrowse link
G mt-Cytb cytochrome b, mitochondrial multiple interactions EXP Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]]; sarpogrelate promotes the reaction [Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYTB protein]] CTD PMID:35202708 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288
JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial multiple interactions EXP [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]] CTD PMID:35202708 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP
ISO
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein]; Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of RELA protein] CTD PMID:34560070 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein]; Carbidopa inhibits the reaction [Cisplatin results in increased phosphorylation of STAT3 protein] CTD PMID:34560070 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased expression of TNF protein]
[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Cisplatin results in increased secretion of TNF protein]; Carbidopa inhibits the reaction [Cisplatin results in increased secretion of TNF protein]
CTD PMID:34560070 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions EXP [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of TPH1 mRNA]; [sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in increased expression of TPH1 protein] CTD PMID:35202708 NCBI chr 7:46,294,065...46,321,961
Ensembl chr 7:46,294,065...46,321,961
JBrowse link
carbinoxamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO carbinoxamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO carbinoxamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
dimenhydrinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO Dimenhydrinate results in decreased activity of BCHE protein CTD PMID:236606 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Dimenhydrinate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
diphenhydramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 affects response to substance EXP ATG5 protein affects the susceptibility to Diphenhydramine CTD PMID:22310178 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
ISO Protons affects the reaction [Diphenhydramine results in decreased activity of BCHE protein] CTD PMID:236606 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Diphenhydramine results in decreased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
decreases expression
decreases response to substance
ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of CXCL8 mRNA]; Diphenhydramine inhibits the reaction [Histamine results in increased expression of CXCL8 protein]; HRH1 protein promotes the reaction [Diphenhydramine results in decreased susceptibility to CXCL8 protein]
Diphenhydramine results in decreased expression of CXCL8 mRNA
CTD PMID:7522859 PMID:9609743 PMID:11336536 PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Ereg epiregulin decreases expression ISO Diphenhydramine results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G F3 coagulation factor III multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of F3] CTD PMID:16009787 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Gnai1 G protein subunit alpha i1 increases response to substance EXP GNAI1 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
JBrowse link
G Gnai2 G protein subunit alpha i2 increases response to substance EXP GNAI2 results in increased susceptibility to Diphenhydramine CTD PMID:14614911 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Hrh1 histamine receptor H1 multiple interactions ISO Diphenhydramine binds to and results in decreased activity of HRH1 protein; Diphenhydramine binds to and results in increased activity of HRH1 protein; Diphenhydramine inhibits the reaction [Pyrilamine binds to HRH1 protein]; HRH1 protein promotes the reaction [Diphenhydramine results in decreased susceptibility to CXCL8 protein]
[Diphenhydramine results in decreased activity of HRH1 protein] which results in decreased susceptibility to Erythromycin
CTD PMID:1912125 PMID:2419744 PMID:2461127 PMID:7522859 PMID:9609743 More... NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
ISO Diphenhydramine results in increased expression of IL1B mRNA
Diphenhydramine results in decreased expression of IL1B mRNA
CTD PMID:28138970 PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il24 interleukin 24 decreases expression ISO Diphenhydramine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of IL6 protein] CTD PMID:11336536 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Diphenhydramine co-treated with PK 11195] binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) multiple interactions ISO Diphenhydramine inhibits the reaction [Histamine results in increased expression of PLA2G4A mRNA] CTD PMID:9609743 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Diphenhydramine results in decreased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Diphenhydramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc22a3 solute carrier family 22 (organic cation transporter), member 3 multiple interactions ISO Diphenhydramine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr17:12,638,859...12,726,591
Ensembl chr17:12,637,847...12,726,591
JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 multiple interactions EXP Diphenhydramine affects the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine]; Diphenhydramine inhibits the reaction [SLC22A5 gene mutant form affects the transport of and affects the abundance of Pyrilamine] CTD PMID:19821448 NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 decreases expression ISO Diphenhydramine results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Diphenhydramine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
entacapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox3 acyl-Coenzyme A oxidase 3, pristanoyl affects binding ISO entacapone binds to ACOX3 protein CTD PMID:19783845 NCBI chr 5:35,740,293...35,772,397
Ensembl chr 5:35,740,384...35,772,696
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects binding ISO entacapone binds to ACSL1 protein CTD PMID:19783845 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects binding ISO entacapone binds to ADPRHL1 protein CTD PMID:19783845 NCBI chr 8:13,268,449...13,304,079
Ensembl chr 8:13,271,663...13,304,162
JBrowse link
G Auh AU RNA binding protein/enoyl-coenzyme A hydratase affects binding ISO entacapone binds to AUH protein CTD PMID:19783845 NCBI chr13:52,989,155...53,083,742
Ensembl chr13:52,989,155...53,083,717
JBrowse link
G Cltc clathrin heavy chain affects binding ISO entacapone binds to CLTC protein CTD PMID:19783845 NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
affects binding
multiple interactions
ISO
EXP
entacapone results in decreased activity of COMT protein
entacapone binds to COMT protein
[entacapone results in decreased activity of COMT protein] which results in increased abundance of Dopamine; entacapone inhibits the reaction [COMT protein results in increased methylation of Levodopa]
CTD PMID:12898346 PMID:15566291 PMID:19783845 PMID:20334432 PMID:23206800 More... NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO entacapone results in increased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial affects binding ISO entacapone binds to ECHS1 protein CTD PMID:19783845 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
JBrowse link
G Ereg epiregulin increases expression ISO entacapone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO entacapone results in decreased expression of GPAM protein CTD PMID:29688484 NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain affects binding ISO entacapone binds to HBB protein CTD PMID:19783845
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 affects binding ISO entacapone binds to HSD17B13 protein CTD PMID:19783845 NCBI chr 5:104,103,308...104,125,254
Ensembl chr 5:104,103,306...104,125,276
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects binding ISO entacapone binds to HSD17B4 protein CTD PMID:19783845 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO entacapone results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression ISO entacapone results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Met met proto-oncogene increases expression ISO entacapone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Pcx pyruvate carboxylase affects binding ISO entacapone binds to PC protein CTD PMID:19783845 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 decreases expression ISO entacapone results in decreased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO entacapone results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 decreases expression ISO entacapone results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO entacapone results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Snca synuclein, alpha multiple interactions ISO entacapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 affects binding ISO entacapone binds to SULT2A1 protein CTD PMID:19783845 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 decreases expression ISO entacapone results in decreased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of entacapone CTD PMID:15802387 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation
decreases glucuronidation
ISO UGT1A9 protein results in increased glucuronidation of entacapone
UGT1A9 protein mutant form results in decreased glucuronidation of entacapone
CTD PMID:15044611 PMID:15802387 PMID:16344532 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
decreases activity
decreases expression
ISO Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased activity of ABCB1 protein
Haloperidol results in decreased expression of ABCB1 mRNA
CTD PMID:15946544 PMID:16810505 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions
decreases expression
ISO Haloperidol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCC1 mRNA
CTD PMID:15946544 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions ISO Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Acadvl acyl-Coenzyme A dehydrogenase, very long chain decreases expression ISO Haloperidol results in decreased expression of ACADVL protein CTD PMID:34122009 NCBI chr11:69,901,009...69,906,254
Ensembl chr11:69,901,009...69,906,237
JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of ACAT1 protein CTD PMID:34122009 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO Haloperidol inhibits the reaction [potassium bromate results in increased activity of ACHE protein] CTD PMID:37865952 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ACSL3 protein CTD PMID:34122009 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Ada adenosine deaminase multiple interactions ISO Haloperidol inhibits the reaction [potassium bromate results in increased activity of ADA protein] CTD PMID:37865952 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159
JBrowse link
G Adam1a a disintegrin and metallopeptidase domain 1a decreases expression ISO Haloperidol results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr 5:121,656,667...121,659,758
Ensembl chr 5:121,656,639...121,660,134
JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions
EXP ADCY5 protein affects the susceptibility to Haloperidol
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol]
CTD PMID:12223546 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
JBrowse link
G Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 affects expression ISO Haloperidol affects the expression of ADCYAP1R1 mRNA CTD PMID:27900577 NCBI chr 6:55,428,486...55,478,440
Ensembl chr 6:55,428,963...55,478,436
JBrowse link
G Adora2a adenosine A2a receptor affects response to substance EXP ADORA2A protein affects the susceptibility to Haloperidol CTD PMID:11172060 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr15:80,832,691...80,855,148
Ensembl chr15:80,832,691...80,855,147
JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 decreases expression EXP Haloperidol results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr17:34,823,164...34,832,392
Ensembl chr17:34,823,236...34,832,423
JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 2:75,662,477...75,761,694
Ensembl chr 2:75,662,521...75,761,694
JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of AK4 protein CTD PMID:34122009 NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases expression ISO Haloperidol results in decreased expression of AKT1 mRNA CTD PMID:15860345 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Akt2 thymoma viral proto-oncogene 2 increases expression ISO Haloperidol results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO Haloperidol results in decreased expression of ALDH18A1 protein CTD PMID:34122009 NCBI chr19:40,538,701...40,576,907
Ensembl chr19:40,538,701...40,576,907
JBrowse link
G Aldoc aldolase C, fructose-bisphosphate increases expression ISO Haloperidol results in increased expression of ALDOC mRNA CTD PMID:15860345 NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ANKHD1 protein CTD PMID:34122009 NCBI chr18:36,693,656...36,791,961
Ensembl chr18:36,693,040...36,791,966
JBrowse link
G Ap2a2 adaptor-related protein complex 2, alpha 2 subunit decreases expression ISO Haloperidol results in decreased expression of AP2A2 mRNA CTD PMID:15860345 NCBI chr 7:141,142,093...141,212,924
Ensembl chr 7:141,142,086...141,212,924
JBrowse link
G Ap2b1 adaptor-related protein complex 2, beta 1 subunit affects expression ISO Haloperidol affects the expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr11:83,189,545...83,295,861
Ensembl chr11:83,189,850...83,295,861
JBrowse link
G Ap2m1 adaptor-related protein complex 2, mu 1 subunit increases expression ISO Haloperidol results in increased expression of AP2M1 protein CTD PMID:34122009 NCBI chr16:20,354,230...20,363,659
Ensembl chr16:20,354,228...20,363,659
JBrowse link
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit increases expression ISO Haloperidol results in increased expression of AP3B1 protein CTD PMID:34122009 NCBI chr13:94,492,332...94,702,838
Ensembl chr13:94,495,468...94,702,825
JBrowse link
G Apod apolipoprotein D increases expression EXP Haloperidol results in increased expression of APOD mRNA CTD PMID:14647396 NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of APPL1 protein CTD PMID:34122009 NCBI chr14:26,640,943...26,692,567
Ensembl chr14:26,640,945...26,693,189
JBrowse link
G Arc activity regulated cytoskeletal-associated protein increases expression
multiple interactions
ISO Haloperidol results in increased expression of ARC mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of ARC mRNA]
CTD PMID:18208916 PMID:19695244 NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression ISO Haloperidol results in decreased expression of ARF1 mRNA CTD PMID:15860345 NCBI chr11:59,102,237...59,119,042
Ensembl chr11:59,102,238...59,119,096
JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression ISO Haloperidol results in decreased expression of ARF3 mRNA CTD PMID:15860345 NCBI chr15:98,635,505...98,660,999
Ensembl chr15:98,634,515...98,661,095
JBrowse link
G Arl3 ADP-ribosylation factor-like 3 decreases expression ISO Haloperidol results in decreased expression of ARL3 mRNA CTD PMID:15860345 NCBI chr19:46,519,548...46,561,621
Ensembl chr19:46,519,535...46,561,637
JBrowse link
G Arl5a ADP-ribosylation factor-like 5A decreases expression ISO Haloperidol results in decreased expression of ARL5A mRNA CTD PMID:15860345 NCBI chr 2:52,287,961...52,314,886
Ensembl chr 2:52,287,963...52,314,913
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression EXP Haloperidol results in increased expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409
JBrowse link
G Asns asparagine synthetase decreases expression ISO Haloperidol results in decreased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254
JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Haloperidol results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 4:9,449,085...9,669,344
Ensembl chr 4:9,448,069...9,669,344
JBrowse link
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide decreases expression ISO Haloperidol results in decreased expression of ATP1A1 mRNA CTD PMID:15860345 NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
JBrowse link
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide decreases expression ISO Haloperidol results in decreased expression of ATP1A3 mRNA CTD PMID:15860345 NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383
JBrowse link
G Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide increases expression ISO Haloperidol results in increased expression of ATP1B1 mRNA CTD PMID:15860345 NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924
JBrowse link
G Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide decreases expression ISO Haloperidol results in decreased expression of ATP1B2 mRNA CTD PMID:15860345 NCBI chr11:69,490,554...69,496,786
Ensembl chr11:69,490,562...69,496,768
JBrowse link
G Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide increases expression ISO Haloperidol results in increased expression of ATP1B3 mRNA CTD PMID:15860345 NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
JBrowse link
G Atp6v1b1 ATPase, H+ transporting, lysosomal V1 subunit B1 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B1 protein CTD PMID:34122009 NCBI chr 6:83,719,999...83,735,837
Ensembl chr 6:83,719,972...83,735,837
JBrowse link
G Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 decreases expression EXP Haloperidol results in decreased expression of ATP6V1B2 mRNA CTD PMID:16465460 NCBI chr 8:69,541,388...69,566,370
Ensembl chr 8:69,541,298...69,566,363
JBrowse link
G Axin2 axin 2 decreases expression ISO Haloperidol results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609
JBrowse link
G Bax BCL2-associated X protein decreases expression
increases expression
ISO Haloperidol results in decreased expression of BAX protein
Haloperidol results in increased expression of BAX mRNA; Haloperidol results in increased expression of BAX protein
CTD PMID:16462815 PMID:17069804 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcat2 branched chain aminotransferase 2, mitochondrial decreases expression ISO Haloperidol results in decreased expression of BCAT2 protein CTD PMID:34122009 NCBI chr 7:45,219,773...45,239,134
Ensembl chr 7:45,219,577...45,239,135
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Haloperidol results in increased expression of BCL2 protein CTD PMID:17069804 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions
increases expression
decreases expression
ISO EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]
Haloperidol results in increased expression of BCL2L1 protein
CTD PMID:16462815 PMID:17805306 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
increases expression
decreases expression
ISO
EXP
BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; Haloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]
Haloperidol results in increased expression of BDNF mRNA
Haloperidol results in increased expression of BDNF protein
Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Haloperidol results in decreased expression of BDNF mRNA; Haloperidol results in decreased expression of BDNF protein
CTD PMID:11488957 PMID:12393228 PMID:12478621 PMID:15168214 PMID:17442543 More... NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein like affects expression ISO Haloperidol affects the expression of BET1L mRNA CTD PMID:15860345 NCBI chr 7:140,433,297...140,437,306
Ensembl chr 7:140,433,307...140,437,490
JBrowse link
G Bop1 block of proliferation 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of BOP1 protein CTD PMID:34122009 NCBI chr15:76,337,188...76,361,449
Ensembl chr15:76,337,189...76,361,477
JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression EXP Haloperidol results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953
JBrowse link
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit decreases expression ISO
EXP
Haloperidol results in decreased expression of CACNA1A mRNA CTD PMID:14647396 PMID:16715494 NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha affects activity ISO Haloperidol affects the activity of CALCA protein CTD PMID:10075105 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Calm2 calmodulin 2 increases expression ISO Haloperidol results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr17:87,740,829...87,754,363
Ensembl chr17:87,740,840...87,754,363
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
increases expression
decreases expression
ISO Haloperidol results in decreased expression of and results in decreased phosphorylation of CAMK2A protein
Haloperidol results in increased expression of CAMK2A mRNA
Haloperidol results in decreased expression of CAMK2A protein
CTD PMID:15860345 PMID:18061412 PMID:19289156 NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II, beta decreases expression ISO Haloperidol results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II, delta decreases expression ISO Haloperidol results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 3:126,389,136...126,639,975
Ensembl chr 3:126,389,951...126,639,975
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression
increases expression
ISO Haloperidol results in decreased expression of CAMK4 protein
Haloperidol results in increased expression of CAMK4 mRNA
CTD PMID:15860345 PMID:19289156 NCBI chr18:33,067,995...33,328,820
Ensembl chr18:33,067,984...33,324,281
JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1, alpha decreases expression ISO Haloperidol results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr11:72,906,869...72,932,899
Ensembl chr11:72,909,834...72,932,899
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta decreases expression ISO Haloperidol results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr 5:122,856,064...122,918,295
Ensembl chr 5:122,869,233...122,917,472
JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CAP1 protein CTD PMID:34122009 NCBI chr 4:122,752,841...122,779,869
Ensembl chr 4:122,752,840...122,779,849
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
ISO BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:15168214 PMID:17805306 PMID:18590723 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
ISO
EXP
Carvedilol inhibits the reaction [Haloperidol results in decreased expression of CAT protein]; Haloperidol results in decreased activity of and results in decreased expression of CAT protein; Zolpidem inhibits the reaction [Haloperidol results in decreased activity of CAT]
Cannabidiol inhibits the reaction [Haloperidol results in decreased activity of CAT protein]
CTD PMID:12010767 PMID:12482469 PMID:16564057 PMID:17513028 PMID:30217539 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr15:103,099,973...103,148,337
Ensembl chr15:103,099,971...103,148,243
JBrowse link
G Ccdc121 coiled-coil domain containing 121 increases expression ISO Haloperidol results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr 5:31,643,205...31,645,820
Ensembl chr 5:31,643,084...31,645,820
JBrowse link
G Cck cholecystokinin increases expression ISO Haloperidol results in increased expression of CCK mRNA CTD PMID:10974607 NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Haloperidol results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd3 cyclin D3 increases expression ISO Haloperidol results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Ccnl1 cyclin L1 increases expression ISO Haloperidol results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 3:65,853,333...65,869,451
Ensembl chr 3:65,853,572...65,865,670
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr16:87,280,213...87,292,757
Ensembl chr16:87,280,214...87,292,761
JBrowse link
G Cdc42 cell division cycle 42 increases expression ISO Haloperidol results in increased expression of CDC42 mRNA CTD PMID:15860345 NCBI chr 4:137,047,011...137,085,007
Ensembl chr 4:137,047,007...137,085,031
JBrowse link
G Cdk4 cyclin dependent kinase 4 increases expression ISO Haloperidol results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
JBrowse link
G Cdk5 cyclin dependent kinase 5 increases expression ISO Haloperidol results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528
JBrowse link
G Cfap161 cilia and flagella associated protein 161 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CFAP161 protein CTD PMID:34122009 NCBI chr 7:83,424,820...83,447,528
Ensembl chr 7:83,423,309...83,444,088
JBrowse link
G Cfdp1 craniofacial development protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CFDP1 protein CTD PMID:34122009 NCBI chr 8:112,493,314...112,580,969
Ensembl chr 8:112,495,123...112,580,923
JBrowse link
G Cfl1 cofilin 1, non-muscle increases expression ISO Haloperidol results in increased expression of CFL1 protein CTD PMID:34122009 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression EXP Haloperidol results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 6:103,487,372...103,709,999
Ensembl chr 6:103,487,547...103,727,172
JBrowse link
G Chn1 chimerin 1 decreases expression EXP Haloperidol results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 2:73,441,004...73,605,723
Ensembl chr 2:73,441,004...73,605,690
JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO Haloperidol results in increased expression of CHORDC1 protein CTD PMID:34122009 NCBI chr 9:18,203,563...18,225,296
Ensembl chr 9:18,203,421...18,228,738
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects response to substance EXP CHRM4 affects the susceptibility to Haloperidol CTD PMID:21269601 NCBI chr 2:91,752,531...91,760,180
Ensembl chr 2:91,757,594...91,759,033
JBrowse link
G Cldn11 claudin 11 decreases expression EXP Haloperidol results in decreased expression of CLDN11 mRNA CTD PMID:17177202 NCBI chr 3:31,204,069...31,218,475
Ensembl chr 3:31,204,069...31,218,473
JBrowse link
G Clta clathrin light chain A affects expression ISO Haloperidol affects the expression of CLTA mRNA CTD PMID:15860345 NCBI chr 4:44,003,816...44,032,846
Ensembl chr 4:44,004,452...44,032,846
JBrowse link
G Cltb clathrin light chain B decreases expression ISO Haloperidol results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr13:54,740,199...54,759,186
Ensembl chr13:54,740,214...54,759,157
JBrowse link
G Cmya5 cardiomyopathy associated 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CMYA5 protein CTD PMID:34122009 NCBI chr13:93,177,221...93,281,278
Ensembl chr13:93,177,221...93,281,232
JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 decreases expression ISO Haloperidol results in decreased expression of CNOT3 protein CTD PMID:34122009 NCBI chr 7:3,646,717...3,664,108
Ensembl chr 7:3,648,267...3,664,108
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression EXP Haloperidol results in decreased expression of CNP mRNA CTD PMID:17177202 NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases methylation
EXP
ISO
CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]
Haloperidol results in increased methylation of CNR1 promoter
Haloperidol inhibits the reaction [Methylazoxymethanol Acetate results in decreased methylation of CNR1 promoter]
CTD PMID:28017790 PMID:30496751 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Coil coilin increases expression ISO Haloperidol results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr11:88,864,761...88,882,439
Ensembl chr11:88,861,078...88,882,439
JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of COPS3 protein CTD PMID:34122009 NCBI chr11:59,708,621...59,739,080
Ensembl chr11:59,708,621...59,730,664
JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Haloperidol results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr 5:100,666,223...100,695,668
Ensembl chr 5:100,666,175...100,695,669
JBrowse link
G Cpn1 carboxypeptidase N, polypeptide 1 increases expression ISO Haloperidol results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr19:43,944,746...43,974,990
Ensembl chr19:43,944,746...43,974,995
JBrowse link
G Cpne3 copine III decreases expression ISO Haloperidol results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 4:19,519,252...19,570,108
Ensembl chr 4:19,519,254...19,570,108
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases expression
increases activity
increases phosphorylation
EXP
ISO
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Haloperidol results in increased expression of CREB1 mRNA; Haloperidol results in increased expression of CREB1 protein
Amphetamine affects the reaction [Haloperidol results in increased activity of CREB1 protein modified form]
CTD PMID:12125044 PMID:12871586 PMID:26894264 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Haloperidol results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression ISO Haloperidol results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr13:95,567,884...95,581,339
Ensembl chr13:95,567,879...95,581,432
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Haloperidol results in decreased expression of CRY1 mRNA CTD PMID:27746588 NCBI chr10:84,967,564...85,020,918
Ensembl chr10:84,967,564...85,020,928
JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide decreases expression ISO Haloperidol results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772
JBrowse link
G Cst3 cystatin C increases expression EXP Haloperidol results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
G Ctnna1 catenin alpha 1 decreases expression ISO Haloperidol results in decreased expression of CTNNA1 protein CTD PMID:34122009 NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
increases expression
multiple interactions
EXP
ISO
Haloperidol results in decreased expression of CTNNB1 mRNA
Haloperidol results in increased expression of CTNNB1 protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]
CTD PMID:16144542 PMID:18797397 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctrl chymotrypsin-like increases expression ISO Haloperidol results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr 8:106,658,626...106,660,494
Ensembl chr 8:106,658,635...106,660,494
JBrowse link
G Ctsk cathepsin K increases expression ISO Haloperidol results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CYB5R1 protein CTD PMID:34122009 NCBI chr 1:134,333,519...134,339,476
Ensembl chr 1:134,333,297...134,339,478
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 affects response to substance ISO CYP2D6 protein polymorphism affects the susceptibility to Haloperidol CTD PMID:15538130 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions ISO CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression EXP Haloperidol results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr 1:165,157,069...165,288,475
Ensembl chr 1:165,156,267...165,288,044
JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression EXP
ISO
Haloperidol results in increased expression of DCLK1 mRNA CTD PMID:15860345 PMID:18797397 NCBI chr 3:55,149,724...55,446,489
Ensembl chr 3:55,149,785...55,446,489
JBrowse link
G Ddx27 DEAD box helicase 27 increases expression ISO Haloperidol results in increased expression of DDX27 protein CTD PMID:34122009 NCBI chr 2:166,857,233...166,876,865
Ensembl chr 2:166,857,113...166,876,867
JBrowse link
G Ddx46 DEAD box helicase 46 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of DDX46 protein CTD PMID:34122009 NCBI chr13:55,782,790...55,829,080
Ensembl chr13:55,782,841...55,829,069
JBrowse link
G Ddx5 DEAD box helicase 5 decreases expression ISO Haloperidol results in decreased expression of DDX5 protein CTD PMID:34122009 NCBI chr11:106,671,181...106,680,011
Ensembl chr11:106,671,181...106,680,011
JBrowse link
G Dennd10 DENN domain containing 10 increases expression ISO Haloperidol results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr19:60,800,029...60,824,673
Ensembl chr19:60,800,023...60,824,665
JBrowse link
G Depp1 DEPP1 autophagy regulator increases expression ISO Haloperidol results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755
JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression ISO Haloperidol results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr10:128,556,000...128,581,002
Ensembl chr10:128,556,003...128,580,724
JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression ISO Haloperidol results in decreased expression of DHX36 protein CTD PMID:34122009 NCBI chr 3:62,375,436...62,414,464
Ensembl chr 3:62,375,434...62,414,425
JBrowse link
G Dhx38 DEAH-box helicase 38 decreases expression ISO Haloperidol results in decreased expression of DHX38 protein CTD PMID:34122009 NCBI chr 8:110,274,631...110,292,493
Ensembl chr 8:110,274,643...110,292,493
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Haloperidol results in decreased expression of DLAT mRNA CTD PMID:15860345 NCBI chr 9:50,545,933...50,571,080
Ensembl chr 9:50,545,933...50,571,080
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Haloperidol results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 7:90,125,399...92,098,454
Ensembl chr 7:90,125,880...92,098,455
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of DNAH1 protein CTD PMID:34122009 NCBI chr14:30,982,332...31,045,926
Ensembl chr14:30,982,332...31,045,853
JBrowse link
G Dnah3 dynein, axonemal, heavy chain 3 increases expression ISO Haloperidol results in increased expression of DNAH3 protein CTD PMID:34122009 NCBI chr 7:119,520,555...119,694,520
Ensembl chr 7:119,521,894...119,694,503
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of DNAJB1 protein CTD PMID:34122009 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression
multiple interactions
ISO Haloperidol results in increased expression of DNAJB11 protein
[Cuprizone co-treated with Haloperidol] results in increased expression of DNAJB11 protein
CTD PMID:34122009 NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384
JBrowse link
G Dpf1 double PHD fingers 1 increases expression EXP Haloperidol results in increased expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 7:29,003,366...29,017,017
Ensembl chr 7:29,003,376...29,017,668
JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO Haloperidol results in decreased expression of DR1 protein CTD PMID:34122009 NCBI chr 5:108,416,763...108,428,387
Ensembl chr 5:108,416,763...108,428,392
JBrowse link
G Drd1 dopamine receptor D1 affects binding
increases expression
decreases expression
affects activity
ISO
EXP
Haloperidol binds to DRD1 protein
Haloperidol results in increased expression of DRD1 protein
Haloperidol results in decreased expression of DRD1 mRNA
Haloperidol affects the activity of DRD1 protein
CTD PMID:8750706 PMID:8794996 PMID:12887421 PMID:16983399 PMID:23611293 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 affects binding
affects activity
multiple interactions
increases expression
affects response to substance
ISO
EXP
DRD2 protein binds to Haloperidol; DRD2 protein binds to Haloperidol analog; Haloperidol binds to DRD2 protein
Haloperidol affects the activity of DRD2 protein
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; cyclo(leucylglycine) inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]; felbamate inhibits the reaction [Haloperidol affects the activity of DRD2 protein]; Haloperidol binds to and results in decreased activity of DRD2 protein; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [iodosulpride binds to DRD2 protein]; Haloperidol inhibits the reaction [Spiperone binds to DRD2 protein]; Haloperidol promotes the reaction [Dopamine binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein]
Haloperidol results in increased expression of DRD2; Haloperidol results in increased expression of DRD2 mRNA; Haloperidol results in increased expression of DRD2 protein
Haloperidol binds to DRD2; Haloperidol binds to DRD2 protein; Haloperidol binds to DRD2 protein alternative form
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Ethanol; [Haloperidol results in increased expression of DRD2 protein] which results in decreased susceptibility to Pentobarbital; Haloperidol binds to and results in decreased activity of DRD2 protein
DRD2 affects the susceptibility to Haloperidol; DRD2 protein affects the susceptibility to Haloperidol
Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 mRNA]; Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]
CTD PMID:1351265 PMID:1361536 PMID:1380082 PMID:2945998 PMID:7845605 More... NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 affects binding
multiple interactions
ISO DRD3 protein binds to Haloperidol analog
Haloperidol affects the reaction [Methylazoxymethanol Acetate results in increased expression of DRD3 mRNA]
CTD PMID:14552778 PMID:32360362 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Drd4 dopamine receptor D4 affects activity
affects binding
ISO Haloperidol affects the activity of DRD4 protein
Haloperidol binds to Drd4 protein
CTD
RGD
PMID:23611293 PMID:8078498 RGD:7248459 NCBI chr 7:140,871,931...140,874,868
Ensembl chr 7:140,871,919...140,876,377
JBrowse link
G Drp2 dystrophin related protein 2 increases expression ISO Haloperidol results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:133,304,868...133,357,323
Ensembl chr  X:133,305,300...133,357,322
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance
ISO DTNBP1 gene polymorphism results in increased susceptibility to Haloperidol
DTNBP1 protein affects the susceptibility to Haloperidol
CTD PMID:19369910 NCBI chr13:45,075,552...45,155,614
Ensembl chr13:45,075,551...45,155,623
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO Haloperidol results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO Haloperidol results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 multiple interactions
increases expression
ISO DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein] CTD PMID:16144542 NCBI chr16:20,335,694...20,352,763
Ensembl chr16:20,335,732...20,352,760
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr19:8,944,405...8,955,544
Ensembl chr19:8,944,405...8,955,843
JBrowse link
G Egr1 early growth response 1 affects expression
multiple interactions
increases expression
ISO
EXP
Haloperidol affects the expression of EGR1 protein
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
Haloperidol results in increased expression of EGR1 mRNA; Haloperidol results in increased expression of EGR1 protein
CTD PMID:12243769 PMID:16452686 PMID:17028028 PMID:17913375 PMID:18208916 More... NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 affects expression
increases expression
decreases expression
EXP
ISO
Haloperidol affects the expression of EGR2 mRNA
Haloperidol results in increased expression of EGR2 mRNA
Haloperidol results in decreased expression of EGR2 protein
CTD PMID:17028028 PMID:18208916 PMID:19401217 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B, subunit 5 epsilon increases expression ISO Haloperidol results in increased expression of EIF2B5 protein CTD PMID:34122009 NCBI chr16:20,317,544...20,328,073
Ensembl chr16:20,317,567...20,328,073
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of EIF5A protein CTD PMID:34122009 NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784
JBrowse link
G Elk1 ELK1, member of ETS oncogene family increases phosphorylation
multiple interactions
EXP
ISO
Haloperidol results in increased phosphorylation of ELK1 protein
Nifedipine affects the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
CTD PMID:12871586 PMID:17913375 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847
JBrowse link
G Eno1 enolase 1, alpha non-neuron increases expression ISO Haloperidol results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:17805306 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 decreases expression ISO Haloperidol results in decreased expression of ERAP1 protein CTD PMID:34122009 NCBI chr13:74,787,692...74,841,321
Ensembl chr13:74,787,687...74,841,320
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO Haloperidol results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression
multiple interactions
ISO Haloperidol results in increased expression of ERBB4 protein
Haloperidol results in increased expression of and results in increased phosphorylation of ERBB4 protein
CTD PMID:18184445 PMID:26961615 NCBI chr 1:68,071,063...69,147,756
Ensembl chr 1:68,071,345...69,147,218
JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of ERGIC1 protein CTD PMID:34122009 NCBI chr17:26,779,736...26,875,908
Ensembl chr17:26,780,463...26,875,908
JBrowse link
G Ezr ezrin decreases expression ISO Haloperidol results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183
JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart affects response to substance
increases expression
EXP
ISO
FABP3 affects the susceptibility to Haloperidol
Haloperidol results in increased expression of FABP3 protein
CTD PMID:20181611 PMID:34122009 NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256
JBrowse link
G Fasn fatty acid synthase increases expression ISO Haloperidol results in increased expression of FASN mRNA CTD PMID:16027736 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 decreases expression ISO Haloperidol results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Haloperidol results in increased expression of FNDC4 mRNA CTD PMID:17175557 NCBI chr 5:31,449,589...31,453,279
Ensembl chr 5:31,449,586...31,453,424
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
decreases expression
EXP
ISO
8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; ifenprodil inhibits the reaction [Haloperidol results in increased expression of FOS protein]; tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; traxoprodil mesylate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]]
Haloperidol results in increased expression of FOS mRNA; Haloperidol results in increased expression of FOS protein
Haloperidol results in decreased expression of FOS mRNA; Haloperidol results in decreased expression of FOS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Dronabinol promotes the reaction [Haloperidol results in increased expression of FOS protein]; Nifedipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Nimodipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Theophylline inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]
CTD PMID:1393566 PMID:9571656 PMID:9748542 PMID:10199625 PMID:10435392 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosb FBJ osteosarcoma oncogene B increases expression
multiple interactions
EXP
ISO
Haloperidol results in increased expression of FOSB protein alternative form
Haloperidol results in increased expression of FOSB modified form; Haloperidol results in increased expression of FOSB mRNA; Haloperidol results in increased expression of FOSB protein
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOSB mRNA]
CTD PMID:8714707 PMID:11180499 PMID:12243769 PMID:15579174 PMID:19695244 More... NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Fosl1 fos-like antigen 1 multiple interactions
increases expression
ISO Amphetamine affects the reaction [Haloperidol results in increased expression of FOSL1 protein]
Haloperidol results in increased expression of FOSL1 mRNA; Haloperidol results in increased expression of FOSL1 protein
CTD PMID:12125044 PMID:18208916 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Fosl2 fos-like antigen 2 increases expression ISO Haloperidol results in increased expression of FOSL2 mRNA CTD PMID:12243769 NCBI chr 5:32,292,599...32,315,184
Ensembl chr 5:32,293,145...32,315,186
JBrowse link
G Fyn Fyn proto-oncogene multiple interactions
increases phosphorylation
affects response to substance
EXP FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein]
Haloperidol results in increased phosphorylation of FYN protein
FYN protein affects the susceptibility to Haloperidol
CTD PMID:16407246 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression EXP Haloperidol results in decreased expression of GABRA1 mRNA CTD PMID:18797397 NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta 1 increases expression ISO Haloperidol results in increased expression of GABRB1 mRNA; Haloperidol results in increased expression of GABRB1 protein CTD PMID:26894264 NCBI chr 5:71,815,264...72,306,915
Ensembl chr 5:71,815,456...72,306,380
JBrowse link
G Gabrb3 GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3 increases expression ISO Haloperidol results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
increases expression
decreases expression
ISO [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein
Haloperidol results in increased expression of GAD1 mRNA
Haloperidol results in decreased expression of GAD1 mRNA; Haloperidol results in decreased expression of GAD1 protein
CTD PMID:12887421 PMID:14519413 PMID:15061247 PMID:15967061 PMID:18923069 More... NCBI chr 2:70,392,109...70,432,358
Ensembl chr 2:70,383,416...70,432,358
JBrowse link
G Gad2 glutamic acid decarboxylase 2 decreases expression
increases expression
ISO Haloperidol results in decreased expression of GAD2 mRNA; Haloperidol results in decreased expression of GAD2 protein
Haloperidol results in increased expression of GAD2 mRNA
CTD PMID:18923069 PMID:19359144 NCBI chr 2:22,512,262...22,583,889
Ensembl chr 2:22,512,217...22,583,886
JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr 8:124,958,133...125,072,461
Ensembl chr 8:124,958,130...125,072,463
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Haloperidol results in increased expression of GAPDH mRNA CTD PMID:15860345 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of GDA protein CTD PMID:34122009 NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Haloperidol results in increased expression of GDPD3 mRNA CTD PMID:17175557 NCBI chr 7:126,365,586...126,374,817
Ensembl chr 7:126,365,506...126,374,821
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Haloperidol results in decreased expression of GFAP protein CTD PMID:34122009 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression ISO Haloperidol results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 6:48,723,131...48,731,134
Ensembl chr 6:48,723,131...48,731,144
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO Haloperidol results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GLO1 protein CTD PMID:34122009 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845
JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO Haloperidol results in decreased expression of GLUL mRNA CTD PMID:15860345 NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469
JBrowse link
G Gna12 guanine nucleotide binding protein, alpha 12 decreases expression ISO Haloperidol results in decreased expression of GNA12 mRNA CTD PMID:15860345 NCBI chr 5:140,745,699...140,816,186
Ensembl chr 5:140,744,163...140,816,186
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression ISO Haloperidol results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression ISO Haloperidol results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression ISO Haloperidol results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 3:108,014,591...108,053,468
Ensembl chr 3:108,014,596...108,053,462
JBrowse link
G Gnao1 guanine nucleotide binding protein, alpha O multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GNAO1 protein CTD PMID:34122009 NCBI chr 8:94,537,213...94,696,016
Ensembl chr 8:94,536,594...94,696,016
JBrowse link
G Gnas GNAS complex locus decreases expression ISO Haloperidol results in decreased expression of GNAS mRNA CTD PMID:15860345 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein] CTD PMID:18603625 NCBI chr14:67,982,717...67,986,889
Ensembl chr14:67,982,630...67,986,888
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial affects expression
multiple interactions
ISO Haloperidol affects the expression of GOT2 mRNA
[Cuprizone co-treated with Haloperidol] results in increased expression of GOT2 protein
CTD PMID:15860345 PMID:34122009 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP Haloperidol results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) decreases expression ISO Haloperidol results in decreased expression of GRIA1 mRNA CTD PMID:15860345 NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070
JBrowse link
G Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) increases expression ISO Haloperidol results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr10:48,969,776...49,666,523
Ensembl chr10:48,970,929...49,664,862
JBrowse link
G Grik4 glutamate receptor, ionotropic, kainate 4 increases expression ISO Haloperidol results in increased expression of GRIK4 mRNA CTD PMID:15860345 NCBI chr 9:42,431,708...42,856,296
Ensembl chr 9:42,429,431...42,855,789
JBrowse link
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) increases expression EXP
ISO
Haloperidol results in increased expression of GRIK5 mRNA CTD PMID:14647396 PMID:15860345 NCBI chr 7:24,709,274...24,775,421
Ensembl chr 7:24,709,274...24,771,771
JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) decreases expression
increases expression
ISO Haloperidol results in decreased expression of GRIN1 mRNA
Haloperidol results in increased expression of GRIN1 mRNA
CTD PMID:12020038 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) decreases expression ISO Haloperidol results in decreased expression of GRIN2A mRNA; Haloperidol results in decreased expression of GRIN2A protein CTD PMID:12608697 PMID:15860345 PMID:18061412 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions
increases phosphorylation
EXP FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein] CTD PMID:16407246 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) increases expression ISO Haloperidol results in increased expression of GRIN2C mRNA CTD PMID:15860345 NCBI chr11:115,139,995...115,158,123
Ensembl chr11:115,139,995...115,158,069
JBrowse link
G Grin2d glutamate receptor, ionotropic, NMDA2D (epsilon 4) decreases expression ISO Haloperidol results in decreased expression of GRIN2D mRNA CTD PMID:18923069 NCBI chr 7:45,481,307...45,520,708
Ensembl chr 7:45,481,307...45,527,802
JBrowse link
G Grin3b glutamate receptor, ionotropic, NMDA3B increases expression ISO Haloperidol results in increased expression of GRIN3B mRNA CTD PMID:15860345 NCBI chr10:79,806,227...79,813,024
Ensembl chr10:79,806,549...79,813,024
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression ISO Haloperidol results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr13:55,592,865...55,608,740
Ensembl chr13:55,592,885...55,608,740
JBrowse link
G Grm1 glutamate receptor, metabotropic 1 increases expression ISO Haloperidol results in increased expression of GRM1 mRNA CTD PMID:15860345 NCBI chr10:10,561,803...10,958,126
Ensembl chr10:10,561,803...10,958,100
JBrowse link
G Grm2 glutamate receptor, metabotropic 2 increases expression ISO Haloperidol results in increased expression of GRM2 mRNA CTD PMID:18923069 NCBI chr 9:106,521,733...106,533,308
Ensembl chr 9:106,520,294...106,533,281
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions
ISO Haloperidol results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]
CTD PMID:16144542 NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression
ISO DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]
Haloperidol results in increased expression of GSK3B mRNA; Haloperidol results in increased expression of GSK3B protein
CTD PMID:16144542 PMID:19359144 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 increases expression ISO Haloperidol results in increased expression of GSTM1 mRNA CTD PMID:15860345 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm2 glutathione S-transferase, mu 2 decreases expression ISO Haloperidol results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions
decreases expression
ISO Haloperidol inhibits the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of GSTP1 mRNA
CTD PMID:15946544 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gtf2e1 general transcription factor II E, polypeptide 1 (alpha subunit) decreases expression ISO Haloperidol results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr16:37,330,158...37,360,151
Ensembl chr16:37,330,152...37,360,151
JBrowse link
G H2ac18 H2A clustered histone 18 increases expression EXP Haloperidol results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 3:96,152,853...96,153,439
Ensembl chr 3:96,152,813...96,153,398
JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Haloperidol results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 3:96,127,728...96,128,209
Ensembl chr 3:96,127,677...96,128,196
JBrowse link
G H2aj H2J.A histone increases expression ISO Haloperidol results in increased expression of H2AJ protein CTD PMID:34122009 NCBI chr 6:136,785,246...136,787,072
Ensembl chr 6:136,785,242...136,787,072
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 5:30,360,251...30,389,591
Ensembl chr 5:30,360,246...30,389,591
JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Haloperidol results in increased expression of HARS1 protein CTD PMID:34122009 NCBI chr18:36,899,581...36,916,258
Ensembl chr18:36,899,581...36,916,258
JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:72,986,400...73,011,430
Ensembl chr  X:72,986,398...73,009,963
JBrowse link
G Higd1a HIG1 domain family, member 1A increases expression EXP Haloperidol results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 9:121,677,623...121,686,862
Ensembl chr 9:121,677,629...121,687,428
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases activity
increases expression
multiple interactions
ISO Haloperidol results in increased activity of HMGCR protein
Haloperidol results in increased expression of HMGCR mRNA
[Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides
CTD PMID:16027736 PMID:17052361 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 increases expression ISO Haloperidol results in increased expression of HMGCS1 mRNA CTD PMID:16027736 PMID:17052361 NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of HNRNPC protein CTD PMID:34122009 NCBI chr14:52,310,834...52,341,462
Ensembl chr14:52,310,834...52,341,485
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression ISO Haloperidol results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157
JBrowse link
G Homer1 homer scaffolding protein 1 multiple interactions
increases expression
ISO Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 PMID:15860345 PMID:20147574 NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637
JBrowse link
G Hpcal4 hippocalcin-like 4 decreases expression ISO Haloperidol results in decreased expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 4:123,077,297...123,088,492
Ensembl chr 4:123,077,020...123,088,494
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO Haloperidol results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Hspg2 perlecan (heparan sulfate proteoglycan 2) decreases expression
multiple interactions
EXP Haloperidol results in decreased expression of HSPG2 mRNA
HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine]
CTD PMID:20072119 NCBI chr 4:137,196,062...137,297,941
Ensembl chr 4:137,196,080...137,297,941
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HSPH1 protein CTD PMID:34122009 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
JBrowse link
G Htr1d 5-hydroxytryptamine (serotonin) receptor 1D decreases expression ISO Haloperidol results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 4:136,150,835...136,171,716
Ensembl chr 4:136,150,835...136,171,709
JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A affects binding
multiple interactions
ISO Haloperidol binds to HTR2A protein
[Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein
CTD PMID:7520908 PMID:12191584 PMID:15380371 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C decreases expression ISO Haloperidol results in decreased expression of HTR2C mRNA CTD PMID:17868938 NCBI chr  X:145,745,509...145,980,273
Ensembl chr  X:145,745,509...145,980,273
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
increases expression
ISO Haloperidol results in decreased expression of ID2 mRNA
Haloperidol results in increased expression of ID2 mRNA
CTD PMID:12437575 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
JBrowse link
G Ikbip IKBKB interacting protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of IKBIP protein CTD PMID:34122009 NCBI chr10:90,918,667...90,938,475
Ensembl chr10:90,918,802...90,938,469
JBrowse link
G Il10 interleukin 10 multiple interactions EXP [Cannabidiol co-treated with Haloperidol] results in increased expression of IL10 protein CTD PMID:30217539 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP Haloperidol results in increased expression of IL1B protein
Cannabidiol inhibits the reaction [Haloperidol results in increased expression of IL1B protein]
CTD PMID:30217539 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP Cannabidiol inhibits the reaction [Haloperidol results in increased expression of IL6 mRNA] CTD PMID:30217539 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ilkap integrin-linked kinase-associated serine/threonine phosphatase 2C decreases expression ISO Haloperidol results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 1:91,301,568...91,326,566
Ensembl chr 1:91,301,583...91,326,537
JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of IMPDH1 protein CTD PMID:34122009 NCBI chr 6:29,200,435...29,216,363
Ensembl chr 6:29,200,433...29,216,363
JBrowse link
G Inha inhibin alpha decreases expression ISO Haloperidol results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 1:75,483,872...75,487,010
Ensembl chr 1:75,483,721...75,487,010
JBrowse link
G Inhbe inhibin beta-E increases expression ISO Haloperidol results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280
JBrowse link
G Jun jun proto-oncogene increases expression
decreases expression
ISO Haloperidol results in increased expression of JUN mRNA; Haloperidol results in increased expression of JUN protein
Haloperidol results in decreased expression of JUN mRNA
CTD PMID:12093589 PMID:12125044 PMID:15860345 PMID:18208916 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene multiple interactions
increases expression
decreases expression
ISO 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]
Haloperidol results in decreased expression of JUNB mRNA
CTD PMID:12093589 PMID:19695244 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 increases expression EXP Haloperidol results in increased expression of KCNA1 mRNA; Haloperidol results in increased expression of KCNA1 protein CTD PMID:18797397 NCBI chr 6:126,613,426...126,622,764
Ensembl chr 6:126,617,360...126,623,347
JBrowse link
G Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 decreases expression EXP Haloperidol results in decreased expression of KCNAB1 mRNA CTD PMID:18797397 NCBI chr 3:64,856,636...65,285,643
Ensembl chr 3:64,856,617...65,285,644
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions
decreases activity
ISO Haloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Haloperidol results in decreased activity of KCNH2 protein
CTD PMID:15671647 PMID:16278312 PMID:16494862 PMID:19583963 PMID:21158687 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kcnip3 Kv channel interacting protein 3, calsenilin decreases expression EXP Haloperidol results in decreased expression of KCNIP3 mRNA; Haloperidol results in decreased expression of KCNIP3 protein CTD PMID:18797397 NCBI chr 2:127,298,418...127,364,014
Ensembl chr 2:127,298,418...127,364,014
JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KDM1A protein CTD PMID:34122009 NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034
JBrowse link
G Kdr kinase insert domain protein receptor increases expression ISO Haloperidol results in increased expression of KDR protein CTD PMID:34122009 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Haloperidol results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 2:49,509,298...49,664,790
Ensembl chr 2:49,509,310...49,664,790
JBrowse link
G Kiz kizuna centrosomal protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of KIZ protein CTD PMID:34122009 NCBI chr 2:146,697,743...146,812,018
Ensembl chr 2:146,697,784...146,812,017
JBrowse link
G Klc1 kinesin light chain 1 decreases expression EXP Haloperidol results in decreased expression of KLC1 mRNA CTD PMID:18797397 NCBI chr12:111,724,869...111,774,278
Ensembl chr12:111,725,283...111,774,278
JBrowse link
G Klc4 kinesin light chain 4 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KLC4 protein CTD PMID:34122009 NCBI chr17:46,941,550...46,957,115
Ensembl chr17:46,941,550...46,956,948
JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr12:69,343,455...69,357,461
Ensembl chr12:69,343,455...69,357,461
JBrowse link
G Kmt2a lysine (K)-specific methyltransferase 2A decreases expression EXP Haloperidol results in decreased expression of KMT2A mRNA CTD PMID:14647396 NCBI chr 9:44,714,652...44,793,492
Ensembl chr 9:44,714,652...44,792,594
JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Haloperidol results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 3:68,979,554...69,034,425
Ensembl chr 3:68,974,482...69,034,446
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog increases expression ISO Haloperidol results in increased expression of KRAS mRNA CTD PMID:15860345 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 multiple interactions
increases expression
ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of KREMEN1 protein
Haloperidol results in increased expression of KREMEN1 protein
CTD PMID:34122009 NCBI chr11:5,141,551...5,212,220
Ensembl chr11:5,141,552...5,211,558
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression EXP Haloperidol results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 3:137,624,316...137,634,523
Ensembl chr 3:137,624,267...137,634,661
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression
increases expression
EXP
ISO
Haloperidol results in decreased expression of LDHB mRNA
Haloperidol results in increased expression of LDHB mRNA
CTD PMID:15860345 PMID:16465460 NCBI chr 6:142,435,975...142,453,683
Ensembl chr 6:142,435,975...142,453,683
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of LGALS1 protein CTD PMID:34122009 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
JBrowse link
G Lipa lysosomal acid lipase A increases expression ISO Haloperidol results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
JBrowse link
G Mag myelin-associated glycoprotein decreases expression EXP Haloperidol results in decreased expression of MAG mRNA CTD PMID:17177202 NCBI chr 7:30,598,600...30,614,347
Ensembl chr 7:30,598,601...30,614,298
JBrowse link
G Map1a microtubule-associated protein 1 A increases expression
decreases expression
ISO Haloperidol results in increased expression of MAP1A mRNA
Haloperidol results in decreased expression of MAP1A protein
CTD PMID:15860345 PMID:34122009 NCBI chr 2:121,119,608...121,141,313
Ensembl chr 2:121,120,081...121,141,313
JBrowse link
G Map2 microtubule-associated protein 2 increases expression ISO Haloperidol results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 decreases expression ISO Haloperidol results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 decreases expression
increases expression
ISO
EXP
Haloperidol results in decreased expression of MAP2K2 mRNA
Haloperidol results in increased expression of MAP2K2 mRNA
CTD PMID:14647396 PMID:15860345 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Map2k5 mitogen-activated protein kinase kinase 5 decreases expression ISO Haloperidol results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 9:63,071,050...63,288,964
Ensembl chr 9:63,071,050...63,285,184
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO Haloperidol results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr13:111,882,962...111,954,803
Ensembl chr13:111,882,962...111,945,527
JBrowse link
G Map3k12 mitogen-activated protein kinase kinase kinase 12 increases expression ISO Haloperidol results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr15:102,406,079...102,425,311
Ensembl chr15:102,406,081...102,425,499
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
decreases expression
multiple interactions
EXP
ISO
Haloperidol results in increased phosphorylation of MAPK1 protein
Haloperidol results in decreased expression of MAPK1 mRNA
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]
CTD PMID:12871586 PMID:15860345 PMID:28017790 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 affects expression ISO Haloperidol affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
EXP Haloperidol results in increased phosphorylation of MAPK3 protein
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]
CTD PMID:12871586 PMID:28017790 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression ISO Haloperidol affects the expression of MAPK6 mRNA CTD PMID:15860345 NCBI chr 9:75,294,064...75,317,303
Ensembl chr 9:75,276,344...75,317,287
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 affects expression ISO Haloperidol affects the expression of MAPK9 mRNA CTD PMID:15860345 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 2:153,583,131...153,615,237
Ensembl chr 2:153,583,194...153,615,230
JBrowse link
G Mas1 MAS1 oncogene decreases expression ISO Haloperidol results in decreased expression of MAS1 mRNA CTD PMID:16715494 NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030
JBrowse link
G Mbp myelin basic protein decreases expression EXP Haloperidol results in decreased expression of MBP mRNA CTD PMID:17177202 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Haloperidol results in increased expression of MCAM protein CTD PMID:34122009 NCBI chr 9:44,045,958...44,054,024
Ensembl chr 9:44,045,766...44,054,024
JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 affects binding ISO Haloperidol binds to MCHR1 protein CTD PMID:16983399 NCBI chr15:81,119,700...81,123,165
Ensembl chr15:81,119,700...81,123,165
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Haloperidol results in decreased expression of MMP10 protein CTD PMID:34122009 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mog myelin oligodendrocyte glycoprotein decreases expression EXP Haloperidol results in decreased expression of MOG mRNA CTD PMID:17177202 NCBI chr17:37,321,632...37,334,290
Ensembl chr17:37,321,635...37,334,290
JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 increases expression ISO Haloperidol results in increased expression of MRPS31 protein CTD PMID:34122009 NCBI chr 8:22,901,356...22,919,685
Ensembl chr 8:22,901,377...22,919,681
JBrowse link
G Myadm myeloid-associated differentiation marker multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of MYADM protein CTD PMID:34122009 NCBI chr 7:3,337,563...3,347,871
Ensembl chr 7:3,337,605...3,348,958
JBrowse link
G Myo5b myosin VB decreases expression ISO Haloperidol results in decreased expression of MYO5B protein CTD PMID:34122009 NCBI chr18:74,575,435...74,905,769
Ensembl chr18:74,574,007...74,904,564
JBrowse link
G Nap1l3 nucleosome assembly protein 1-like 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NAP1L3 protein CTD PMID:34122009 NCBI chr  X:121,304,257...121,307,082
Ensembl chr  X:121,304,262...121,307,098
JBrowse link
G Ncan neurocan decreases expression EXP Haloperidol results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr 8:70,545,735...70,573,494
Ensembl chr 8:70,545,735...70,573,523
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Haloperidol results in decreased expression of NCAPH protein CTD PMID:34122009 NCBI chr 2:126,945,729...126,975,857
Ensembl chr 2:126,945,729...126,975,874
JBrowse link
G Ncl nucleolin increases expression EXP Haloperidol results in increased expression of NCL mRNA CTD PMID:14647396 NCBI chr 1:86,272,441...86,287,177
Ensembl chr 1:86,272,441...86,287,122
JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of NDUFV1 protein CTD PMID:34122009 NCBI chr19:4,057,499...4,062,755
Ensembl chr19:4,057,384...4,062,806
JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 decreases expression EXP Haloperidol results in decreased expression of NEDD4 mRNA CTD PMID:18797397 NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 decreases expression ISO Haloperidol results in decreased expression of NFKB1 protein CTD PMID:16500086 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) decreases expression ISO Haloperidol results in decreased expression of NGFR mRNA CTD PMID:16513140 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561
JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 decreases expression ISO Haloperidol results in decreased expression of NIFK protein CTD PMID:34122009 NCBI chr 1:118,249,573...118,261,561
Ensembl chr 1:118,249,569...118,261,552
JBrowse link
G Nop14 NOP14 nucleolar protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NOP14 protein CTD PMID:34122009 NCBI chr 5:34,795,880...34,817,566
Ensembl chr 5:34,795,880...34,817,492
JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression EXP Haloperidol results in increased expression of NOP53 mRNA CTD PMID:14647396 NCBI chr 7:15,671,760...15,680,033
Ensembl chr 7:15,670,108...15,679,999
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression
EXP Cannabidiol inhibits the reaction [Haloperidol results in increased expression of NOS2 mRNA] CTD PMID:30217539 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nppa natriuretic peptide type A affects activity ISO Haloperidol affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nptx2 neuronal pentraxin 2 decreases expression ISO Haloperidol results in decreased expression of NPTX2 mRNA CTD PMID:18208916 NCBI chr 5:144,482,697...144,494,288
Ensembl chr 5:144,482,712...144,494,288
JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
decreases expression
ISO Haloperidol promotes the reaction [Amphetamine results in decreased expression of NPY protein]
Haloperidol results in increased expression of NPY protein
Haloperidol results in decreased expression of NPY mRNA
CTD PMID:7644023 PMID:15985714 PMID:16516965 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NQO1 protein CTD PMID:34122009 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Haloperidol results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO Haloperidol results in increased expression of NR1D1 mRNA CTD PMID:11564422 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects response to substance
multiple interactions
increases expression
decreases expression
EXP
ISO
NR4A1 affects the susceptibility to Haloperidol
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]
Haloperidol results in decreased expression of NR4A1 mRNA
CTD PMID:10987852 PMID:11564422 PMID:14603264 PMID:19695244 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Haloperidol results in increased expression of NR4A3 mRNA CTD PMID:19695244 NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Haloperidol results in increased expression of NRG1 protein CTD PMID:18184445 PMID:26961615 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Nsf N-ethylmaleimide sensitive fusion protein decreases expression ISO Haloperidol results in decreased expression of NSF mRNA
Haloperidol results in decreased expression of NSF protein
CTD PMID:15860345 PMID:34122009 NCBI chr11:103,712,608...103,844,882
Ensembl chr11:103,712,608...103,844,882
JBrowse link
G Nts neurotensin multiple interactions
increases expression
EXP
ISO
SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of NTS mRNA; Haloperidol results in increased expression of NTS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]; Theophylline inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]
CTD PMID:10199625 PMID:11120399 PMID:11602683 PMID:12887421 PMID:14603264 More... NCBI chr10:102,317,617...102,326,294
Ensembl chr10:102,317,617...102,326,347
JBrowse link
G Numbl numb-like decreases expression EXP Haloperidol results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 7:26,957,884...26,981,570
Ensembl chr 7:26,957,858...26,981,569
JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Haloperidol results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr 5:92,563,399...92,583,117
Ensembl chr 5:92,563,399...92,583,078
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 increases expression ISO Haloperidol results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Oprl1 opioid receptor-like 1 affects response to substance EXP OPRL1 affects the susceptibility to Haloperidol CTD PMID:16237164 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:20184921 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198
JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression EXP Haloperidol results in increased expression of OSBPL8 mRNA CTD PMID:14647396 NCBI chr10:111,000,663...111,133,110
Ensembl chr10:111,000,613...111,133,110
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 increases expression EXP Haloperidol results in increased expression of PARK7 mRNA CTD PMID:14647396 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr10:7,503,608...7,556,922
Ensembl chr10:7,505,137...7,556,900
JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor increases expression EXP Haloperidol results in increased expression of PCSK1N mRNA CTD PMID:14647396 NCBI chr  X:7,786,061...7,790,649
Ensembl chr  X:7,786,061...7,790,649
JBrowse link
G Pde10a phosphodiesterase 10A increases expression ISO Haloperidol results in increased expression of PDE10A mRNA; Haloperidol results in increased expression of PDE10A protein CTD PMID:18222493 NCBI chr17:8,742,719...9,205,480
Ensembl chr17:8,744,204...9,205,480
JBrowse link
G Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent increases expression ISO
EXP
Haloperidol results in increased expression of PDE1B mRNA; Haloperidol results in increased expression of PDE1B protein CTD PMID:14647396 PMID:18222493 NCBI chr15:103,411,461...103,438,483
Ensembl chr15:103,411,461...103,438,479
JBrowse link
G Pde4a phosphodiesterase 4A, cAMP specific decreases expression ISO Haloperidol results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 9:21,076,998...21,124,544
Ensembl chr 9:21,077,010...21,124,544
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific multiple interactions ISO Haloperidol inhibits the reaction [potassium bromate results in increased activity of PDE5A protein] CTD PMID:37865952 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Haloperidol results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 3:141,945,346...142,101,480
Ensembl chr 3:141,945,351...142,101,454
JBrowse link
G Pdyn prodynorphin multiple interactions ISO [1-aminocyclopentane-1,2,4-tricarboxylic acid co-treated with Haloperidol] results in increased expression of PDYN mRNA CTD PMID:17224239 NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764
JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 decreases expression ISO Haloperidol results in decreased expression of PDZRN3 protein CTD PMID:34122009 NCBI chr 6:101,126,568...101,354,858
Ensembl chr 6:101,126,570...101,354,858
JBrowse link
G Penk preproenkephalin multiple interactions
increases expression
EXP
ISO
3,4-dicarboxyphenylglycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; Docosahexaenoic Acids inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Tretinoin inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
Haloperidol results in increased expression of PENK mRNA; Haloperidol results in increased expression of PENK protein
1-aminocyclopentane-1,2,4-tricarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 1-aminoindan-1,5-dicarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 2-(2,3-dicarboxycyclopropyl)glycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
CTD PMID:3838946 PMID:7637876 PMID:12373537 PMID:12727308 PMID:12834887 More... NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819
JBrowse link
G Per1 period circadian clock 1 increases expression ISO Haloperidol results in increased expression of PER1 mRNA CTD PMID:27746588 NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786
JBrowse link
G Pfdn5 prefoldin 5 increases expression EXP Haloperidol results in increased expression of PFDN5 mRNA CTD PMID:14647396 NCBI chr15:102,234,551...102,239,925
Ensembl chr15:102,234,551...102,240,308
JBrowse link
G Pfkp phosphofructokinase, platelet increases expression
multiple interactions
ISO Haloperidol results in increased expression of PFKP mRNA
[Cuprizone co-treated with Haloperidol] results in increased expression of PFKP protein
CTD PMID:15860345 PMID:34122009 NCBI chr13:6,629,910...6,699,096
Ensembl chr13:6,629,804...6,698,813
JBrowse link
G Pfn1 profilin 1 increases expression ISO Haloperidol results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr11:70,542,670...70,547,625
Ensembl chr11:70,542,676...70,545,470
JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression ISO Haloperidol results in increased expression of PGK1 mRNA CTD PMID:15860345 NCBI chr  X:105,230,706...105,247,305
Ensembl chr  X:105,230,706...105,247,305
JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases expression EXP Haloperidol results in increased expression of PHACTR1 mRNA CTD PMID:14647396 NCBI chr13:42,833,909...43,292,002
Ensembl chr13:42,834,099...43,292,002
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression ISO Haloperidol results in decreased expression of PICALM mRNA CTD PMID:15860345 NCBI chr 7:89,778,711...89,858,655
Ensembl chr 7:89,779,421...89,862,673
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression ISO Haloperidol results in decreased expression of PIK3R3 mRNA CTD PMID:16715494 NCBI chr 4:116,078,593...116,160,253
Ensembl chr 4:116,078,815...116,160,253
Ensembl chr 4:116,078,815...116,160,253
JBrowse link
G Pkib protein kinase inhibitor beta, cAMP dependent, testis specific decreases expression ISO Haloperidol results in decreased expression of PKIB mRNA CTD PMID:15860345 NCBI chr10:57,508,077...57,617,208
Ensembl chr10:57,508,077...57,617,208
JBrowse link
G Pkm pyruvate kinase, muscle increases expression ISO Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
JBrowse link
G Plp1 proteolipid protein (myelin) 1 decreases expression EXP Haloperidol results in decreased expression of PLP1 mRNA CTD PMID:17177202 PMID:18797397 NCBI chr  X:135,720,897...135,739,331
Ensembl chr  X:135,723,420...135,740,482
JBrowse link
G Plpbp pyridoxal phosphate binding protein increases expression ISO Haloperidol results in increased expression of PLPBP protein CTD PMID:34122009 NCBI chr 8:27,530,801...27,546,160
Ensembl chr 8:27,532,583...27,546,160
JBrowse link
G Pls3 plastin 3 (T-isoform) decreases expression ISO Haloperidol results in decreased expression of PLS3 protein CTD PMID:34122009 NCBI chr  X:74,829,259...74,918,788
Ensembl chr  X:74,829,260...74,918,788
JBrowse link
G Pmpca peptidase (mitochondrial processing) alpha increases expression ISO Haloperidol results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 2:26,275,554...26,287,134
Ensembl chr 2:26,279,351...26,287,134
JBrowse link
G Ppa1 pyrophosphatase (inorganic) 1 increases expression ISO Haloperidol results in increased expression of PPA1 protein CTD PMID:34122009 NCBI chr10:61,484,400...61,509,944
Ensembl chr10:61,484,331...61,509,947
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions EXP [Cannabidiol co-treated with Haloperidol] results in increased expression of PPARGC1A protein CTD PMID:30217539 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ppm1a protein phosphatase 1A, magnesium dependent, alpha isoform decreases expression ISO Haloperidol results in decreased expression of PPM1A mRNA CTD PMID:15860345 NCBI chr12:72,804,231...72,846,593
Ensembl chr12:72,804,229...72,846,593
JBrowse link
G Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform decreases expression ISO Haloperidol results in decreased expression of PPM1B mRNA CTD PMID:15860345 NCBI chr17:85,264,169...85,331,420
Ensembl chr17:85,264,169...85,331,419
JBrowse link
G Ppm1f protein phosphatase 1F (PP2C domain containing) multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr16:16,714,314...16,745,239
Ensembl chr16:16,714,333...16,745,228
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression ISO Haloperidol results in decreased expression of PPP1CB mRNA CTD PMID:15860345 NCBI chr 5:32,616,192...32,651,057
Ensembl chr 5:32,616,187...32,674,777
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression ISO Haloperidol results in decreased expression of PPP1CC mRNA CTD PMID:15860345 NCBI chr 5:122,296,338...122,313,336
Ensembl chr 5:122,296,341...122,313,336
JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory inhibitor subunit 14B multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr19:6,952,416...6,954,692
Ensembl chr19:6,952,336...6,954,692
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A decreases expression ISO Haloperidol results in decreased expression of PPP1R1A mRNA CTD PMID:15860345 NCBI chr15:103,438,706...103,446,465
Ensembl chr15:103,438,706...103,446,430
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B increases phosphorylation EXP Haloperidol results in increased phosphorylation of PPP1R1B protein CTD PMID:12871586 NCBI chr11:98,239,232...98,248,622
Ensembl chr11:98,239,230...98,248,622
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory inhibitor subunit 2 decreases expression ISO Haloperidol results in decreased expression of PPP1R2 mRNA CTD PMID:15860345 NCBI chr16:31,070,359...31,094,095
Ensembl chr16:31,070,355...31,094,095
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B decreases expression ISO Haloperidol results in decreased expression of PPP1R9B protein CTD PMID:16844384 NCBI chr11:94,882,038...94,897,724
Ensembl chr11:94,881,861...94,897,725
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform decreases expression ISO Haloperidol results in decreased expression of PPP2CA mRNA CTD PMID:15860345 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform decreases expression ISO Haloperidol results in decreased expression of PPP2CB mRNA CTD PMID:15860345 NCBI chr 8:34,089,672...34,109,831
Ensembl chr 8:34,089,653...34,109,469
JBrowse link
G Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha increases expression ISO Haloperidol results in increased expression of PPP2R1A mRNA CTD PMID:15860345 NCBI chr17:21,165,716...21,186,167
Ensembl chr17:21,165,573...21,186,178
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases expression ISO Haloperidol results in decreased expression of PPP2R2A mRNA CTD PMID:15860345 NCBI chr14:67,251,505...67,309,920
Ensembl chr14:67,251,505...67,309,893
JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform multiple interactions
decreases expression
ISO [Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Haloperidol results in decreased expression of PPP3CA mRNA; Haloperidol results in decreased expression of PPP3CA protein
CTD PMID:16033416 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit decreases expression
multiple interactions
EXP
ISO
Haloperidol results in decreased expression of PPP5C mRNA
[Cuprizone co-treated with Haloperidol] results in decreased expression of PPP5C protein
CTD PMID:14647396 PMID:34122009 NCBI chr 7:16,738,575...16,761,812
Ensembl chr 7:16,738,565...16,761,849
JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha increases expression ISO Haloperidol results in increased expression of PRKACA mRNA; Haloperidol results in increased expression of PRKACA protein CTD PMID:15860345 PMID:26894264 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072
JBrowse link
G Prkacb protein kinase, cAMP dependent, catalytic, beta increases expression ISO Haloperidol results in increased expression of PRKACB mRNA CTD PMID:15860345 NCBI chr 3:146,435,334...146,518,691
Ensembl chr 3:146,435,329...146,518,745
JBrowse link
G Prkar2a protein kinase, cAMP dependent regulatory, type II alpha multiple interactions
increases expression
ISO Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein]
[Cuprizone co-treated with Haloperidol] results in decreased expression of PRKAR2A protein
Haloperidol results in increased expression of PRKAR2A mRNA; Haloperidol results in increased expression of PRKAR2A protein
CTD PMID:11907174 PMID:34122009 NCBI chr 9:108,569,342...108,627,643
Ensembl chr 9:108,566,513...108,627,635
JBrowse link
G Prkar2b protein kinase, cAMP dependent regulatory, type II beta multiple interactions
increases expression
decreases expression
ISO Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein]
Haloperidol results in increased expression of PRKAR2B mRNA; Haloperidol results in increased expression of PRKAR2B protein
Haloperidol results in decreased expression of PRKAR2B mRNA
CTD PMID:11907174 PMID:15860345 NCBI chr12:32,008,468...32,111,639
Ensembl chr12:32,008,475...32,111,295
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases expression
ISO [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein
Haloperidol results in increased expression of PRKCB mRNA
CTD PMID:15860345 PMID:15967061 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
JBrowse link
G Prkce protein kinase C, epsilon increases expression ISO Haloperidol results in increased expression of PRKCE mRNA CTD PMID:15860345 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
JBrowse link
G Prkcsh protein kinase C substrate 80K-H multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 9:21,914,314...21,925,521
Ensembl chr 9:21,914,102...21,925,518
JBrowse link
G Prkcz protein kinase C, zeta increases expression ISO Haloperidol results in increased expression of PRKCZ mRNA CTD PMID:15860345 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818
JBrowse link
G Prl prolactin affects expression
increases secretion
multiple interactions
increases expression
ISO Haloperidol affects the expression of PRL protein
Haloperidol results in increased secretion of PRL protein
Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Dopamine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [talipexole results in decreased secretion of PRL protein]; LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- inhibits the reaction [Haloperidol results in increased expression of PRL protein]; Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein]
CTD PMID:1304992 PMID:1380082 PMID:2136057 PMID:3019639 PMID:3158510 More... NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Prpf19 pre-mRNA processing factor 19 increases expression ISO Haloperidol results in increased expression of PRPF19 protein CTD PMID:34122009 NCBI chr19:10,872,595...10,886,923
Ensembl chr19:10,872,595...10,886,923
JBrowse link
G Prpf38b PRP38 pre-mRNA processing factor 38 (yeast) domain containing B decreases expression EXP Haloperidol results in decreased expression of PRPF38B mRNA CTD PMID:14647396 NCBI chr 3:108,810,121...108,819,055
Ensembl chr 3:108,810,121...108,819,043
JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression EXP Haloperidol results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr17:35,368,052...35,384,877
Ensembl chr17:35,368,052...35,383,873
JBrowse link
G Prxl2a peroxiredoxin like 2A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PRXL2A protein CTD PMID:34122009 NCBI chr14:40,715,692...40,735,790
Ensembl chr14:40,715,697...40,735,745
JBrowse link
G Psmb9 proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) decreases expression ISO Haloperidol results in decreased expression of PSMB9 mRNA CTD PMID:16452686 NCBI chr17:34,401,006...34,406,347
Ensembl chr17:34,400,961...34,406,738
JBrowse link
G Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PSMD12 protein CTD PMID:34122009 NCBI chr11:107,370,354...107,388,862
Ensembl chr11:107,370,310...107,395,188
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Haloperidol results in increased expression of PTGS2 mRNA CTD PMID:30217539 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptma prothymosin alpha increases expression ISO Haloperidol results in increased expression of PTMA protein CTD PMID:34122009 NCBI chr 1:86,454,442...86,458,434
Ensembl chr 1:86,454,448...86,458,434
JBrowse link
G Ptms parathymosin increases expression EXP Haloperidol results in increased expression of PTMS mRNA CTD PMID:14647396 NCBI chr 6:124,890,638...124,894,909
Ensembl chr 6:124,890,644...124,897,066
JBrowse link
G Pura purine rich element binding protein A increases expression ISO Haloperidol results in increased expression of PURA protein CTD PMID:34122009 NCBI chr18:36,413,614...36,434,575
Ensembl chr18:36,414,150...36,425,588
JBrowse link
G Purb purine rich element binding protein B decreases expression ISO Haloperidol results in decreased expression of PURB protein CTD PMID:34122009 NCBI chr11:6,417,599...6,426,076
Ensembl chr11:6,417,599...6,425,917
JBrowse link
G Pvalb parvalbumin multiple interactions ISO Haloperidol inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr15:78,075,312...78,090,600
Ensembl chr15:78,075,314...78,090,600
JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr11:120,527,591...120,534,602
Ensembl chr11:120,526,538...120,534,595
JBrowse link
G Pygm muscle glycogen phosphorylase decreases expression ISO Haloperidol results in decreased expression of PYGM protein CTD PMID:34122009 NCBI chr19:6,434,438...6,448,494
Ensembl chr19:6,434,429...6,448,489
JBrowse link
G Qki quaking, KH domain containing RNA binding increases expression ISO Haloperidol results in increased expression of QKI mRNA alternative form CTD PMID:19335891 NCBI chr17:10,425,480...10,538,706
Ensembl chr17:10,421,530...10,538,783
JBrowse link
G Rab10 RAB10, member RAS oncogene family increases expression ISO Haloperidol results in increased expression of RAB10 mRNA CTD PMID:15860345 NCBI chr12:3,297,428...3,359,969
Ensembl chr12:3,297,428...3,359,969
JBrowse link
G Rab11a RAB11A, member RAS oncogene family increases expression ISO Haloperidol results in increased expression of RAB11A mRNA CTD PMID:15860345 NCBI chr 9:64,622,582...64,645,038
Ensembl chr 9:64,622,581...64,645,040
JBrowse link
G Rab12 RAB12, member RAS oncogene family increases expression ISO Haloperidol results in increased expression of RAB12 mRNA CTD PMID:12437575 NCBI chr17:66,801,507...66,826,712
Ensembl chr17:66,801,507...66,826,724
JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression ISO Haloperidol results in increased expression of RAB28 mRNA CTD PMID:15860345 NCBI chr 5:41,782,316...41,865,535
Ensembl chr 5:41,782,319...41,865,500
JBrowse link
G Rab4a RAB4A, member RAS oncogene family decreases expression ISO Haloperidol results in decreased expression of RAB4A mRNA CTD PMID:15860345 NCBI chr 8:124,532,748...124,562,030
Ensembl chr 8:124,532,724...124,562,026
JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RAB5A protein CTD PMID:34122009 NCBI chr17:53,786,262...53,814,706
Ensembl chr17:53,786,262...53,814,708
JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression ISO Haloperidol results in increased expression of RAB6A mRNA CTD PMID:15860345 NCBI chr 7:100,256,778...100,290,475
Ensembl chr 7:100,256,617...100,290,475
JBrowse link
G Rab7 RAB7, member RAS oncogene family decreases expression ISO Haloperidol results in decreased expression of RAB7A mRNA CTD PMID:15860345 NCBI chr 6:87,976,088...88,022,252
Ensembl chr 6:87,976,088...88,022,252
JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression ISO Haloperidol results in decreased expression of RAB8A mRNA CTD PMID:15860345 NCBI chr 8:72,915,044...72,935,210
Ensembl chr 8:72,915,044...72,937,748
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression ISO Haloperidol results in increased expression of RAC1 mRNA CTD PMID:15860345 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
JBrowse link
G Rala v-ral simian leukemia viral oncogene A (ras related) increases expression ISO Haloperidol results in increased expression of RALA mRNA CTD PMID:15860345 NCBI chr13:18,055,160...18,118,802
Ensembl chr13:18,055,156...18,118,824
JBrowse link
G Ralb v-ral simian leukemia viral oncogene B increases expression ISO Haloperidol results in increased expression of RALB mRNA CTD PMID:15860345 NCBI chr 1:119,398,035...119,432,512
Ensembl chr 1:119,398,035...119,432,524
JBrowse link
G Ranbp3 RAN binding protein 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of RANBP3 protein CTD PMID:34122009 NCBI chr17:56,980,225...57,018,769
Ensembl chr17:56,980,294...57,018,764
JBrowse link
G Rap1b RAS related protein 1b increases expression ISO Haloperidol results in increased expression of RAP1B mRNA CTD PMID:15860345 NCBI chr10:117,650,502...117,681,879
Ensembl chr10:117,649,776...117,681,940
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor (GEF) 4 decreases expression EXP Haloperidol results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 2:71,811,559...72,087,818
Ensembl chr 2:71,811,584...72,087,818
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO Haloperidol results in increased expression of RARB mRNA alternative form CTD PMID:11564422 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924
JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization ISO Haloperidol affects the localization of RASGRF1 protein CTD PMID:17092607 NCBI chr 9:89,791,565...89,909,032
Ensembl chr 9:89,791,961...89,909,030
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression ISO Haloperidol results in decreased expression of RASGRP1 mRNA CTD PMID:15860345 NCBI chr 2:117,110,464...117,173,358
Ensembl chr 2:117,110,474...117,173,482
JBrowse link
G Rcn1 reticulocalbin 1 multiple interactions
decreases expression
ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RCN1 protein
Haloperidol results in decreased expression of RCN1 protein
CTD PMID:34122009 NCBI chr 2:105,216,293...105,229,664
Ensembl chr 2:105,216,636...105,229,664
JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO Haloperidol results in decreased expression of RDH11 protein CTD PMID:34122009 NCBI chr12:79,221,007...79,238,629
Ensembl chr12:79,221,111...79,239,067
JBrowse link
G Rdx radixin decreases expression ISO Haloperidol results in decreased expression of RDX protein CTD PMID:34122009 NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) increases expression ISO Haloperidol results in increased expression of RELA protein CTD PMID:18554768 PMID:18590723 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Reln reelin decreases expression ISO Haloperidol results in decreased expression of RELN mRNA; Haloperidol results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 5:22,089,452...22,549,703
Ensembl chr 5:22,089,452...22,549,700
JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Haloperidol results in increased expression of RGS2 mRNA CTD PMID:11409749 PMID:11516571 NCBI chr 1:143,875,076...143,879,887
Ensembl chr 1:143,875,076...143,879,899
JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression ISO Haloperidol results in increased expression of RGS4 mRNA CTD PMID:15860345 NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211
JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression ISO Haloperidol results in increased expression of RGS8 mRNA CTD PMID:15860345 NCBI chr 1:153,528,612...153,573,415
Ensembl chr 1:153,528,771...153,576,069
JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance EXP RGS9 affects the susceptibility to Haloperidol CTD PMID:15728856 NCBI chr11:109,116,174...109,189,013
Ensembl chr11:109,116,181...109,188,955
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Haloperidol results in decreased expression of RHOA mRNA CTD PMID:15860345 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 decreases expression ISO Haloperidol results in decreased expression of RIMS1 mRNA CTD PMID:15860345 NCBI chr 1:22,356,196...22,845,239
Ensembl chr 1:22,356,475...22,845,203
JBrowse link
G Rorb RAR-related orphan receptor beta decreases expression ISO Haloperidol results in decreased expression of RORB mRNA CTD PMID:11564422 NCBI chr19:18,907,966...19,088,560
Ensembl chr19:18,907,969...19,088,560
JBrowse link
G Rpl13 ribosomal protein L13 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL13 protein CTD PMID:34122009 NCBI chr 8:123,829,089...123,831,983
Ensembl chr 8:123,829,089...123,831,983
JBrowse link
G Rpl18a ribosomal protein L18A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL18A protein CTD PMID:34122009 NCBI chr 8:71,347,366...71,350,087
Ensembl chr 8:71,347,366...71,350,056
JBrowse link
G Rpl19 ribosomal protein L19 decreases expression
multiple interactions
ISO Haloperidol results in decreased expression of RPL19 protein
[Cuprizone co-treated with Haloperidol] results in increased expression of RPL19 protein
CTD PMID:34122009 NCBI chr11:97,912,829...97,921,319
Ensembl chr11:97,917,536...97,921,318
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Haloperidol results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr15:34,440,649...34,443,405
Ensembl chr15:34,440,651...34,443,786
JBrowse link
G Rpl6 ribosomal protein L6 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL6 protein CTD PMID:34122009 NCBI chr 5:121,342,564...121,347,304
Ensembl chr 5:121,342,544...121,347,304
JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL8 protein CTD PMID:34122009 NCBI chr15:76,788,271...76,790,518
Ensembl chr15:76,788,278...76,790,514
JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression EXP Haloperidol results in increased expression of RPLP2 mRNA CTD PMID:14647396 NCBI chr 7:141,027,564...141,031,272
Ensembl chr 7:141,027,283...141,031,498
JBrowse link
G Rps10 ribosomal protein S10 increases expression EXP Haloperidol results in increased expression of RPS10 mRNA CTD PMID:14647396 NCBI chr17:27,849,389...27,854,218
Ensembl chr17:27,849,392...27,855,643
JBrowse link
G Rps16 ribosomal protein S16 decreases expression ISO Haloperidol results in decreased expression of RPS16 protein CTD PMID:34122009 NCBI chr 7:28,050,114...28,052,123
Ensembl chr 7:28,050,077...28,052,580
JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Haloperidol results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 3:90,119,974...90,120,955
Ensembl chr 3:90,119,829...90,120,958
JBrowse link
G Rps27a ribosomal protein S27A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr11:29,495,842...29,498,040
Ensembl chr11:29,495,846...29,498,109
JBrowse link
G Rps9 ribosomal protein S9 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPS9 protein CTD PMID:34122009 NCBI chr 7:3,707,035...3,709,896
Ensembl chr 7:3,706,992...3,709,896
JBrowse link
G Rrad Ras-related associated with diabetes increases expression ISO Haloperidol results in increased expression of RRAD mRNA CTD PMID:15860345 NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959
JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression ISO Haloperidol results in decreased expression of RRBP1 protein CTD PMID:34122009 NCBI chr 2:143,789,315...143,853,216
Ensembl chr 2:143,789,315...143,853,183
JBrowse link
G Rsf1 remodeling and spacing factor 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of RSF1 protein CTD PMID:34122009 NCBI chr 7:97,229,103...97,341,989
Ensembl chr 7:97,229,096...97,341,985
JBrowse link
G Rtn4 reticulon 4 decreases expression EXP Haloperidol results in decreased expression of RTN4 mRNA CTD PMID:18797397 NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331
JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance
increases expression
EXP
ISO
RXRG protein affects the susceptibility to Haloperidol
Haloperidol results in increased expression of RXRG mRNA alternative form
CTD PMID:10336693 PMID:11564422 NCBI chr 1:167,425,902...167,467,191
Ensembl chr 1:167,425,953...167,467,192
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) decreases expression EXP Haloperidol results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SAE1 protein CTD PMID:34122009 NCBI chr 7:16,054,161...16,121,821
Ensembl chr 7:16,054,159...16,121,731
JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Haloperidol results in decreased expression of SARS1 protein CTD PMID:34122009 NCBI chr 3:108,332,180...108,352,575
Ensembl chr 3:108,332,181...108,352,525
JBrowse link
G Satb2 special AT-rich sequence binding protein 2 decreases expression ISO Haloperidol results in decreased expression of SATB2 protein CTD PMID:34122009 NCBI chr 1:56,833,145...57,019,350
Ensembl chr 1:56,833,140...57,017,809
JBrowse link
G Sbds SBDS ribosome maturation factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of SBDS protein CTD PMID:34122009 NCBI chr 5:130,274,573...130,284,371
Ensembl chr 5:130,274,572...130,284,371
JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Haloperidol results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO Haloperidol results in increased expression of SCD mRNA CTD PMID:16027736 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SEC61A1 protein CTD PMID:34122009 NCBI chr 6:88,480,589...88,495,782
Ensembl chr 6:88,480,561...88,495,887
JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Haloperidol results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr10:42,637,492...42,708,510
Ensembl chr10:42,637,492...42,708,510
JBrowse link
G Serpina3b serine (or cysteine) peptidase inhibitor, clade A, member 3B increases expression ISO Haloperidol results in increased expression of SERPINA3 mRNA; Haloperidol results in increased expression of SERPINA3 protein CTD PMID:17175557 PMID:34122009 NCBI chr12:104,094,245...104,105,805
Ensembl chr12:104,094,255...104,105,804
JBrowse link
G Serpini1 serine (or cysteine) peptidase inhibitor, clade I, member 1 decreases expression EXP Haloperidol results in decreased expression of SERPINI1 mRNA CTD PMID:18797397 NCBI chr 3:75,464,800...75,549,830
Ensembl chr 3:75,464,854...75,550,802
JBrowse link
G Sf3b4 splicing factor 3b, subunit 4 decreases expression ISO Haloperidol results in decreased expression of SF3B4 protein CTD PMID:34122009 NCBI chr 3:96,079,822...96,084,880
Ensembl chr 3:96,079,648...96,084,880
JBrowse link
G Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SGCD protein CTD PMID:34122009 NCBI chr11:46,861,904...47,880,309
Ensembl chr11:46,787,080...47,879,796
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Haloperidol results in increased expression of SGK1 mRNA CTD PMID:16452686 NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SH3KBP1 protein CTD PMID:34122009 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr11:32,297,777...32,378,189
Ensembl chr11:32,297,820...32,378,173
JBrowse link
G Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 increases expression EXP Haloperidol results in increased expression of SLC17A6 mRNA; Haloperidol results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 7:51,271,578...51,320,874
Ensembl chr 7:51,271,754...51,320,867
JBrowse link
G Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 affects response to substance EXP SLC17A8 protein affects the susceptibility to Haloperidol CTD PMID:18278042 NCBI chr10:89,409,882...89,457,111
Ensembl chr10:89,409,882...89,457,115
JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 affects binding ISO Haloperidol binds to SLC18A2 protein CTD PMID:7912402 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444
JBrowse link
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 decreases expression ISO Haloperidol results in decreased expression of SLC1A1 mRNA CTD PMID:12873733 NCBI chr19:28,812,535...28,891,360
Ensembl chr19:28,812,449...28,891,360
JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 decreases expression ISO Haloperidol results in decreased expression of SLC1A2 mRNA CTD PMID:12873733 NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
JBrowse link
G Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 decreases expression ISO Haloperidol results in decreased expression of SLC1A3 mRNA CTD PMID:15860345 NCBI chr15:8,663,608...8,742,648
Ensembl chr15:8,663,608...8,740,248
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SLC25A3 protein CTD PMID:34122009 NCBI chr10:90,952,436...90,959,902
Ensembl chr10:90,952,436...90,959,921
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression ISO Haloperidol results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
JBrowse link
G Slc39a7 solute carrier family 39 (zinc transporter), member 7 increases expression EXP Haloperidol results in increased expression of SLC39A7 mRNA CTD PMID:14647396 NCBI chr17:34,247,240...34,250,664
Ensembl chr17:34,247,243...34,250,656
JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 multiple interactions
increases expression
EXP
ISO
SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of SLC6A3 protein
CTD PMID:14698760 PMID:17069804 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791
JBrowse link
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 increases expression ISO Haloperidol results in increased expression of SLC6A4 CTD PMID:12007678 NCBI chr11:76,889,423...76,923,169
Ensembl chr11:76,889,429...76,923,166
JBrowse link
G Snap25 synaptosomal-associated protein 25 affects response to substance
affects expression
ISO SNAP25 gene SNP affects the susceptibility to Haloperidol
Haloperidol affects the expression of SNAP25 mRNA
CTD PMID:15823421 PMID:15860345 NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348
JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 increases expression EXP Haloperidol results in increased expression of SNRPD2 mRNA CTD PMID:14647396 NCBI chr 7:18,883,370...18,886,659
Ensembl chr 7:18,883,647...18,887,467
JBrowse link
G Sod1 superoxide dismutase 1, soluble increases expression
decreases expression
multiple interactions
ISO Haloperidol results in increased expression of SOD1 mRNA
Haloperidol results in decreased expression of SOD1 protein
Clozapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Haloperidol results in decreased activity of and results in decreased expression of SOD1 protein; olanzapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Risperidone inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]
CTD PMID:12482469 PMID:12752374 PMID:16564057 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression
multiple interactions
ISO Haloperidol results in decreased expression of SOD2 mRNA; Haloperidol results in decreased expression of SOD2 protein
Haloperidol results in decreased activity of and results in decreased expression of SOD2 protein
CTD PMID:12482469 PMID:15860345 PMID:16564057 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sod3 superoxide dismutase 3, extracellular increases expression ISO Haloperidol results in increased expression of SOD3 mRNA CTD PMID:15860345 NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
JBrowse link
G Speg SPEG complex locus increases expression ISO Haloperidol results in increased expression of SPEG protein CTD PMID:34122009 NCBI chr 1:75,351,931...75,408,964
Ensembl chr 1:75,351,941...75,408,964
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions ISO Haloperidol results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Srpra signal recognition particle receptor alpha decreases expression ISO Haloperidol results in decreased expression of SRPRA protein CTD PMID:34122009 NCBI chr 9:35,122,499...35,128,299
Ensembl chr 9:35,111,471...35,159,269
JBrowse link
G Srsf2 serine and arginine-rich splicing factor 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SRSF2 protein CTD PMID:34122009 NCBI chr11:116,740,723...116,744,511
Ensembl chr11:116,740,727...116,743,920
JBrowse link
G Srsf5 serine and arginine-rich splicing factor 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr12:80,992,308...80,997,277
Ensembl chr12:80,992,278...80,997,281
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Haloperidol results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr19:6,998,064...7,017,394
Ensembl chr19:6,998,070...7,017,335
JBrowse link
G Strn4 striatin, calmodulin binding protein 4 increases expression EXP Haloperidol results in increased expression of STRN4 mRNA CTD PMID:14647396 NCBI chr 7:16,549,814...16,574,856
Ensembl chr 7:16,549,814...16,574,856
JBrowse link
G Stt3a STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of STT3A protein CTD PMID:34122009 NCBI chr 9:36,640,640...36,678,918
Ensembl chr 9:36,640,640...36,678,975
JBrowse link
G Stx1a syntaxin 1A (brain) increases expression ISO Haloperidol results in increased expression of STX1A mRNA CTD PMID:15860345 NCBI chr 5:135,051,473...135,079,954
Ensembl chr 5:135,052,336...135,079,954
JBrowse link
G Stx1b syntaxin 1B affects expression ISO Haloperidol affects the expression of STX1B mRNA CTD PMID:15860345 NCBI chr 7:127,403,072...127,423,703
Ensembl chr 7:127,403,072...127,423,721
JBrowse link
G Stx4a syntaxin 4A (placental) increases expression ISO Haloperidol results in increased expression of STX4 mRNA CTD PMID:15860345 NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191
JBrowse link
G Stx5a syntaxin 5A decreases expression ISO Haloperidol results in decreased expression of STX5 mRNA CTD PMID:15860345 NCBI chr19:8,718,788...8,733,006
Ensembl chr19:8,718,777...8,733,433
JBrowse link
G Stx7 syntaxin 7 decreases expression ISO Haloperidol results in decreased expression of STX7 mRNA CTD PMID:15860345 NCBI chr10:24,025,182...24,064,859
Ensembl chr10:24,025,200...24,066,120
JBrowse link
G Stx8 syntaxin 8 affects expression ISO Haloperidol affects the expression of STX8 mRNA CTD PMID:15860345 NCBI chr11:67,857,237...68,097,974
Ensembl chr11:67,857,019...68,097,974
JBrowse link
G Supt3 SPT3, SAGA and STAGA complex component increases expression ISO Haloperidol results in increased expression of SUPT3H mRNA CTD PMID:16715494 NCBI chr17:45,088,005...45,430,181
Ensembl chr17:45,088,039...45,430,177
JBrowse link
G Syn2 synapsin II increases expression ISO Haloperidol results in increased expression of SYN2 mRNA CTD PMID:15860345 NCBI chr 6:115,111,863...115,259,587
Ensembl chr 6:115,111,863...115,258,967
JBrowse link
G Sypl1 synaptophysin like 1 decreases expression EXP Haloperidol results in decreased expression of SYPL1 mRNA CTD PMID:18797397 NCBI chr12:33,003,874...33,029,503
Ensembl chr12:33,003,890...33,029,859
JBrowse link
G Syt11 synaptotagmin XI increases expression ISO Haloperidol results in increased expression of SYT11 mRNA CTD PMID:15860345 NCBI chr 3:88,652,006...88,682,466
Ensembl chr 3:88,652,007...88,682,471
JBrowse link
G Syt3 synaptotagmin III decreases expression ISO Haloperidol results in decreased expression of SYT3 mRNA CTD PMID:15860345 NCBI chr 7:44,032,197...44,049,454
Ensembl chr 7:44,033,526...44,049,611
JBrowse link
G Syt4 synaptotagmin IV affects expression ISO Haloperidol affects the expression of SYT4 mRNA CTD PMID:15860345 NCBI chr18:31,570,861...31,580,468
Ensembl chr18:31,570,861...31,580,459
JBrowse link
G Tac1 tachykinin 1 increases expression ISO Haloperidol results in increased expression of TAC1 mRNA CTD PMID:10974607 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tagln transgelin decreases expression ISO Haloperidol results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356
JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Haloperidol results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr 1:172,327,813...172,334,942
Ensembl chr 1:172,327,614...172,334,947
JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) decreases expression ISO Haloperidol results in decreased expression of TAP1 mRNA CTD PMID:16452686 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199
JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression EXP Haloperidol results in increased expression of TATDN1 mRNA CTD PMID:14647396 NCBI chr15:58,762,002...58,805,605
Ensembl chr15:58,762,004...58,805,587
JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO Haloperidol results in decreased expression of TCAF1 protein CTD PMID:34122009 NCBI chr 6:42,644,933...42,687,065
Ensembl chr 6:42,644,936...42,687,022
JBrowse link
G Tcerg1 transcription elongation regulator 1 (CA150) multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TCERG1 protein CTD PMID:34122009 NCBI chr18:42,644,369...42,708,850
Ensembl chr18:42,644,552...42,708,858
JBrowse link
G Tgoln1 trans-golgi network protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 6:72,585,403...72,593,983
Ensembl chr 6:72,585,415...72,593,983
JBrowse link
G Th tyrosine hydroxylase increases expression ISO Haloperidol results in increased expression of TH protein CTD PMID:17028028 NCBI chr 7:142,446,516...142,453,732
Ensembl chr 7:142,446,489...142,484,865
JBrowse link
G Thra thyroid hormone receptor alpha increases expression
decreases expression
ISO Haloperidol results in increased expression of THRA mRNA alternative form
Haloperidol results in decreased expression of THRA mRNA alternative form
CTD PMID:11564422 NCBI chr11:98,631,539...98,659,832
Ensembl chr11:98,631,464...98,659,832
JBrowse link
G Tln2 talin 2 decreases expression ISO Haloperidol results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 9:67,124,371...67,541,357
Ensembl chr 9:67,124,369...67,466,985
JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 decreases expression ISO Haloperidol results in decreased expression of TM9SF2 protein CTD PMID:34122009 NCBI chr14:122,342,290...122,397,015
Ensembl chr14:122,344,450...122,397,016
JBrowse link
G Tmem109 transmembrane protein 109 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TMEM109 protein CTD PMID:34122009 NCBI chr19:10,848,021...10,859,107
Ensembl chr19:10,848,024...10,859,365
JBrowse link
G Tmod3 tropomodulin 3 decreases expression ISO Haloperidol results in decreased expression of TMOD3 protein CTD PMID:34122009 NCBI chr 9:75,405,066...75,466,939
Ensembl chr 9:75,404,989...75,466,939
JBrowse link
G Tmprss2 transmembrane protease, serine 2 increases expression ISO Haloperidol results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr16:97,365,882...97,460,741
Ensembl chr16:97,365,882...97,412,395
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
Haloperidol affects the reaction [Phencyclidine affects the expression of TNF mRNA]
Cannabidiol inhibits the reaction [Haloperidol results in increased expression of TNF mRNA]
Haloperidol results in increased expression of TNF protein
CTD PMID:16478754 PMID:18554768 PMID:18590723 PMID:30217539 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnik TRAF2 and NCK interacting kinase decreases expression EXP Haloperidol results in decreased expression of TNIK mRNA CTD PMID:14647396 NCBI chr 3:28,317,362...28,724,734
Ensembl chr 3:28,317,363...28,730,007
JBrowse link
G Tor1a torsin family 1, member A (torsin A) affects response to substance EXP TOR1A gene mutant form affects the susceptibility to Haloperidol CTD PMID:20227500 NCBI chr 2:30,850,573...30,857,930
Ensembl chr 2:30,850,639...30,857,945
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Haloperidol results in increased expression of TPI1 mRNA CTD PMID:15860345 NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259
JBrowse link
G Trf transferrin decreases expression EXP Haloperidol results in decreased expression of TRF mRNA CTD PMID:17177202 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643
JBrowse link
G Trim2 tripartite motif-containing 2 decreases expression EXP Haloperidol results in decreased expression of TRIM2 mRNA CTD PMID:14647396 NCBI chr 3:84,067,746...84,215,659
Ensembl chr 3:84,067,746...84,214,184
JBrowse link
G Trim23 tripartite motif-containing 23 decreases expression ISO Haloperidol results in decreased expression of TRIM23 mRNA CTD PMID:15860345 NCBI chr13:104,315,187...104,339,983
Ensembl chr13:104,315,305...104,339,880
JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression ISO Haloperidol results in decreased expression of TRIM28 protein CTD PMID:34122009 NCBI chr 7:12,758,079...12,764,959
Ensembl chr 7:12,733,041...12,764,962
JBrowse link
G Trmt13 tRNA methyltransferase 13 decreases expression ISO Haloperidol results in decreased expression of TRMT13 protein CTD PMID:34122009 NCBI chr 3:116,365,706...116,408,236
Ensembl chr 3:116,374,742...116,408,236
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO Haloperidol results in increased expression of TP53 mRNA; Haloperidol results in increased expression of TP53 protein CTD PMID:16462815 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TRPV5 protein CTD PMID:34122009 NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703
JBrowse link
G Ttbk1 tau tubulin kinase 1 increases expression ISO Haloperidol results in increased expression of TTBK1 protein CTD PMID:34122009 NCBI chr17:46,751,577...46,798,596
Ensembl chr17:46,753,374...46,798,601
JBrowse link
G Tubb4b tubulin, beta 4B class IVB multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TUBB4B protein CTD PMID:34122009 NCBI chr 2:25,112,170...25,114,714
Ensembl chr 2:25,112,172...25,114,714
JBrowse link
G Txlna taxilin alpha multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TXLNA protein CTD PMID:34122009 NCBI chr 4:129,519,870...129,534,867
Ensembl chr 4:129,519,871...129,534,858
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression EXP Haloperidol results in increased expression of UBA52 mRNA CTD PMID:14647396 NCBI chr 8:70,960,913...70,963,067
Ensembl chr 8:70,960,913...70,963,451
JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of UBC protein CTD PMID:34122009 NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266
JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 increases expression EXP Haloperidol results in increased expression of UBE2R2 mRNA CTD PMID:14647396 NCBI chr 4:41,136,021...41,193,370
Ensembl chr 4:41,135,743...41,193,380
JBrowse link
G Ubqln4 ubiquilin 4 decreases expression ISO Haloperidol results in decreased expression of UBQLN4 protein CTD PMID:34122009 NCBI chr 3:88,460,984...88,477,032
Ensembl chr 3:88,461,065...88,477,032
JBrowse link
G Ubtf upstream binding transcription factor, RNA polymerase I decreases expression ISO Haloperidol results in decreased expression of UBTF protein CTD PMID:34122009 NCBI chr11:102,195,393...102,214,738
Ensembl chr11:102,195,386...102,210,568
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 increases expression ISO Haloperidol results in increased expression of UGP2 protein CTD PMID:34122009 NCBI chr11:21,271,126...21,321,267
Ensembl chr11:21,271,138...21,321,201
JBrowse link
G Ugt8a UDP galactosyltransferase 8A decreases expression EXP Haloperidol results in decreased expression of UGT8A mRNA CTD PMID:17177202 NCBI chr 3:125,655,071...125,732,301
Ensembl chr 3:125,658,920...125,732,268
JBrowse link
G Unc13a unc-13 homolog A decreases expression ISO Haloperidol results in decreased expression of UNC13A mRNA CTD PMID:15860345 NCBI chr 8:72,079,356...72,124,418
Ensembl chr 8:72,077,061...72,124,401
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI increases expression EXP Haloperidol results in increased expression of UQCR11 mRNA CTD PMID:14647396 NCBI chr10:80,238,831...80,242,655
Ensembl chr10:80,238,831...80,242,664
JBrowse link
G Uso1 USO1 vesicle docking factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of USO1 protein CTD PMID:34122009 NCBI chr 5:92,285,770...92,350,659
Ensembl chr 5:92,285,797...92,350,657
JBrowse link
G Usp5 ubiquitin specific peptidase 5 (isopeptidase T) increases expression
multiple interactions
ISO Haloperidol results in increased expression of USP5 protein
[Cuprizone co-treated with Haloperidol] results in increased expression of USP5 protein
CTD PMID:34122009 NCBI chr 6:124,791,982...124,806,404
Ensembl chr 6:124,791,982...124,806,447
JBrowse link
G Usp7 ubiquitin specific peptidase 7 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of USP7 protein CTD PMID:34122009 NCBI chr16:8,506,586...8,574,931
Ensembl chr16:8,507,459...8,610,172
JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression
increases expression
ISO Haloperidol results in decreased expression of VAMP1 mRNA
Haloperidol results in increased expression of VAMP1 mRNA
CTD PMID:15860345 NCBI chr 6:125,192,544...125,199,269
Ensembl chr 6:125,192,514...125,222,927
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression
increases expression
ISO Haloperidol results in decreased expression of VAMP2 mRNA
Haloperidol results in increased expression of VAMP2 mRNA
CTD PMID:15860345 NCBI chr11:68,979,354...68,983,207
Ensembl chr11:68,979,316...68,983,210
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression ISO Haloperidol results in decreased expression of VIPR2 mRNA CTD PMID:27900577 NCBI chr12:116,041,040...116,117,842
Ensembl chr12:116,041,346...116,109,881
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO Haloperidol results in increased expression of VLDLR protein CTD PMID:19359144 NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631
JBrowse link
G Vsnl1 visinin-like 1 decreases expression ISO Haloperidol results in decreased expression of VSNL1 mRNA CTD PMID:12437575 NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr12:108,825,956...108,860,095
Ensembl chr12:108,825,956...108,860,100
JBrowse link
G Wbp1l WW domain binding protein 1 like decreases expression EXP Haloperidol results in decreased expression of WBP1L mRNA CTD PMID:14647396 NCBI chr19:46,587,545...46,645,828
Ensembl chr19:46,587,523...46,645,828
JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Haloperidol results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 1:60,110,520...60,137,659
Ensembl chr 1:60,108,944...60,137,804
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Haloperidol results in increased expression of WIPI1 mRNA CTD PMID:17175557 NCBI chr11:109,464,347...109,502,215
Ensembl chr11:109,464,157...109,502,793
JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Haloperidol results in decreased expression of XIRP2 protein CTD PMID:34122009 NCBI chr 2:67,276,343...67,356,964
Ensembl chr 2:67,004,178...67,356,959
JBrowse link
G Xpnpep1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble increases expression ISO Haloperidol results in increased expression of XPNPEP1 protein CTD PMID:34122009 NCBI chr19:52,919,710...53,027,093
Ensembl chr19:52,920,357...53,028,645
JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Haloperidol results in decreased expression of ZFR protein CTD PMID:34122009 NCBI chr15:12,117,649...12,185,535
Ensembl chr15:12,117,917...12,185,769
JBrowse link
lisuride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenergic receptor, alpha 1a multiple interactions ISO Lisuride binds to and results in decreased activity of ADRA1A protein; Lisuride promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] CTD PMID:16545797 NCBI chr14:66,872,705...67,009,549
Ensembl chr14:66,872,700...67,008,617
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 multiple interactions ISO [Lisuride binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Lisuride binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 NCBI chr19:35,935,815...36,035,533
Ensembl chr19:35,936,134...36,034,907
JBrowse link
G Ifng interferon gamma increases expression ISO Lisuride results in increased expression of IFNG CTD PMID:7948314 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Prl prolactin multiple interactions
decreases secretion
ISO Lisuride inhibits the reaction [Metoclopramide results in increased secretion of PRL protein]; Lisuride results in decreased expression of and results in decreased secretion of PRL protein
Lisuride analog results in decreased secretion of PRL protein; Lisuride results in decreased secretion of PRL protein
CTD PMID:386688 PMID:6492995 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Lisuride inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
memantine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO asoxime chloride inhibits the reaction [Memantine inhibits the reaction [Soman results in decreased activity of ACHE protein]]; Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Memantine inhibits the reaction [Soman results in decreased activity of ACHE protein]
Memantine results in decreased activity of ACHE protein
CTD PMID:2241428 PMID:30588862 PMID:30682440 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] CTD PMID:21290839 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Arc activity regulated cytoskeletal-associated protein multiple interactions EXP Memantine inhibits the reaction [Lipopolysaccharides results in decreased expression of ARC protein] CTD PMID:34474083 NCBI chr15:74,540,930...74,544,419
Ensembl chr15:74,540,932...74,544,419
JBrowse link
G Bax BCL2-associated X protein affects expression ISO Memantine affects the expression of BAX protein CTD PMID:29226720 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
ISO Memantine analog inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]; Memantine inhibits the reaction [Glutamic Acid results in decreased expression of BCL2 protein]
Memantine results in decreased expression of BCL2 protein
CTD PMID:29226720 PMID:32092300 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Memantine results in decreased expression of BIRC5 protein CTD PMID:29226720 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein] CTD PMID:24333387 NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224
JBrowse link
G Capn1 calpain 1 multiple interactions EXP Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of CAPN1 protein] CTD PMID:34474083 NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927
JBrowse link
G Casp1 caspase 1 multiple interactions EXP Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein] CTD PMID:34474083 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO
EXP
Memantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP3 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [salsolinol results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
Memantine results in increased expression of CASP3 protein
Memantine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CASP3 protein]
Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]
CTD PMID:17996985 PMID:19959636 PMID:20347921 PMID:24333387 PMID:29226720 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Memantine inhibits the reaction [benzo(e)pyrene results in increased activity of CASP7 protein]; Memantine inhibits the reaction [catechol results in increased activity of CASP7 protein] CTD PMID:19959636 PMID:20347921 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp9 caspase 9 increases expression ISO Memantine results in increased expression of CASP9 protein CTD PMID:29226720 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Memantine results in decreased expression of CCND1 protein CTD PMID:29226720 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cdk4 cyclin dependent kinase 4 increases expression ISO Memantine results in increased expression of CDK4 protein CTD PMID:29226720 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein] CTD PMID:23562514 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions ISO
EXP
Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]
Memantine inhibits the reaction [Lipopolysaccharides results in decreased expression of DLG4 protein]
CTD PMID:24333387 PMID:34474083 NCBI chr11:69,908,029...69,938,107
Ensembl chr11:69,907,768...69,938,348
JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr 8:14,145,793...14,903,426
Ensembl chr 8:14,145,865...14,897,680
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO
EXP
Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]
Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of GFAP protein]
CTD PMID:24333387 PMID:34474083 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions EXP Memantine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of GRIN2B protein] CTD PMID:34474083 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein]]; Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein] CTD PMID:32092300 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:34474083 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Itgam integrin alpha M multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein] CTD PMID:24333387 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein] CTD PMID:23562514 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein] CTD PMID:23562514 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO Memantine results in decreased expression of MYC protein CTD PMID:29226720 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nefl neurofilament, light polypeptide multiple interactions ISO Memantine inhibits the reaction [N-Methylaspartate results in decreased expression of NEFL mRNA]; Memantine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:34474083 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Penk preproenkephalin multiple interactions ISO Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA] CTD PMID:14642644 NCBI chr 4:4,133,536...4,138,815
Ensembl chr 4:4,133,531...4,138,819
JBrowse link
G Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform multiple interactions EXP [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride co-treated with Memantine] results in increased expression of PPP2CA mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Okadaic Acid co-treated with Fingolimod Hydrochloride co-treated with Memantine] results in increased expression of PPP2CA protein CTD PMID:33069748 NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
JBrowse link
G Prkcg protein kinase C, gamma increases expression ISO Memantine results in increased expression of PRKCG mRNA CTD PMID:11169168 NCBI chr 7:3,352,038...3,379,615
Ensembl chr 7:3,337,704...3,379,615
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein]
Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:24333387 PMID:34474083 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
mesulergine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B affects binding
multiple interactions
EXP mesulergine binds to HTR2B protein
Fluoxetine promotes the reaction [mesulergine binds to HTR2B protein]
CTD PMID:11930908 NCBI chr 1:86,025,268...86,043,960
Ensembl chr 1:86,026,748...86,039,692
JBrowse link
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C affects binding
multiple interactions
ISO mesulergine binds to HTR2C protein
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [mesulergine binds to HTR2C protein]
Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Carbamazepine inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]; Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]; Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]; Plant Extracts inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Plant Extracts inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]
CTD PMID:18083778 PMID:19439326 PMID:19700373 PMID:29458138 NCBI chr  X:145,745,509...145,980,273
Ensembl chr  X:145,745,509...145,980,273
JBrowse link
G Htr7 5-hydroxytryptamine (serotonin) receptor 7 affects binding
multiple interactions
ISO mesulergine binds to HTR7 protein
[mesulergine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; mesulergine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]
CTD PMID:14578406 PMID:20827463 NCBI chr19:35,935,815...36,035,533
Ensembl chr19:35,936,134...36,034,907
JBrowse link
G Prl prolactin multiple interactions ISO mesulergine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:1421203 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
metixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO methixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
orphenadrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700017B05Rik RIKEN cDNA 1700017B05 gene affects expression ISO Orphenadrine affects the expression of C8H15ORF39 mRNA CTD PMID:23665939 NCBI chr 9:57,159,605...57,169,882
Ensembl chr 9:57,160,400...57,169,895
JBrowse link
G 1810055G02Rik RIKEN cDNA 1810055G02 gene affects expression ISO Orphenadrine affects the expression of C1H11ORF24 mRNA CTD PMID:23665939 NCBI chr19:3,758,343...3,767,882
Ensembl chr19:3,758,293...3,767,881
JBrowse link
G A2m alpha-2-macroglobulin affects expression ISO Orphenadrine affects the expression of A2M mRNA CTD PMID:23665939 NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects expression ISO Orphenadrine affects the expression of ABCB1B mRNA CTD PMID:23665939 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions ISO [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA CTD PMID:23665939 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 affects expression ISO Orphenadrine affects the expression of ABCC3 mRNA CTD PMID:23665939 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcd2 ATP-binding cassette, sub-family D member 2 affects expression ISO Orphenadrine affects the expression of ABCD2 mRNA CTD PMID:23665939 NCBI chr15:91,029,874...91,076,013
Ensembl chr15:91,030,074...91,076,002
JBrowse link
G Ablim3 actin binding LIM protein family, member 3 affects expression ISO Orphenadrine affects the expression of ABLIM3 mRNA CTD PMID:23665939 NCBI chr18:61,932,463...62,044,956
Ensembl chr18:61,932,463...62,044,895
JBrowse link
G Ace2 angiotensin converting enzyme 2 affects expression ISO Orphenadrine affects the expression of ACE2 mRNA CTD PMID:23665939 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Acer3 alkaline ceramidase 3 affects expression ISO Orphenadrine affects the expression of ACER3 mRNA CTD PMID:23665939 NCBI chr 7:97,863,015...97,970,415
Ensembl chr 7:97,855,596...97,970,415
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression ISO Orphenadrine affects the expression of ACSL5 mRNA CTD PMID:23665939 NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 affects expression ISO Orphenadrine affects the expression of ACSM3 mRNA CTD PMID:23665939 NCBI chr 7:119,360,106...119,384,119
Ensembl chr 7:119,360,146...119,386,736
JBrowse link
G Adgrg2 adhesion G protein-coupled receptor G2 affects expression ISO Orphenadrine affects the expression of ADGRG2 mRNA CTD PMID:23665939 NCBI chr  X:159,173,315...159,281,072
Ensembl chr  X:159,173,686...159,281,066
JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 affects expression ISO Orphenadrine affects the expression of ADGRV1 mRNA CTD PMID:23665939 NCBI chr13:81,243,187...81,781,504
Ensembl chr13:81,243,187...81,781,273
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression ISO Orphenadrine affects the expression of ADH4 mRNA CTD PMID:23665939 NCBI chr 3:138,121,217...138,138,444
Ensembl chr 3:138,121,227...138,136,653
JBrowse link
G Adora1 adenosine A1 receptor affects expression ISO Orphenadrine affects the expression of ADORA1 mRNA CTD PMID:23665939 NCBI chr 1:134,126,953...134,163,195
Ensembl chr 1:134,126,963...134,163,169
JBrowse link
G Adora2a adenosine A2a receptor affects expression ISO Orphenadrine affects the expression of ADORA2A mRNA CTD PMID:23665939 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Adrb2 adrenergic receptor, beta 2 affects expression ISO Orphenadrine affects the expression of ADRB2 mRNA CTD PMID:23665939 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Ajuba ajuba LIM protein affects expression ISO Orphenadrine affects the expression of JUB mRNA CTD PMID:23665939 NCBI chr14:54,804,926...54,815,118
Ensembl chr14:54,804,929...54,815,015
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects expression ISO Orphenadrine affects the expression of ALDH1A1 mRNA CTD PMID:23665939 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney affects expression ISO Orphenadrine affects the expression of ALPL mRNA CTD PMID:23665939 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Als2cl ALS2 C-terminal like affects expression ISO Orphenadrine affects the expression of ALS2CL mRNA CTD PMID:23665939 NCBI chr 9:110,709,203...110,729,598
Ensembl chr 9:110,708,938...110,729,598
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression ISO Orphenadrine affects the expression of AMIGO3 mRNA CTD PMID:23665939 NCBI chr 9:107,930,358...107,932,900
Ensembl chr 9:107,930,358...107,932,900
JBrowse link
G Amotl2 angiomotin-like 2 affects expression ISO Orphenadrine affects the expression of AMOTL2 mRNA CTD PMID:23665939 NCBI chr 9:102,594,290...102,610,616
Ensembl chr 9:102,593,871...102,610,617
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression ISO Orphenadrine affects the expression of ANGPTL4 mRNA CTD PMID:23665939 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Angptl6 angiopoietin-like 6 affects expression ISO Orphenadrine affects the expression of ANGPTL6 mRNA CTD PMID:23665939 NCBI chr 9:20,785,104...20,791,116
Ensembl chr 9:20,785,104...20,791,023
JBrowse link
G Ankrd9 ankyrin repeat domain 9 affects expression ISO Orphenadrine affects the expression of ANKRD9 mRNA CTD PMID:23665939 NCBI chr12:110,942,854...110,945,516
Ensembl chr12:110,941,787...110,945,474
JBrowse link
G Ano1 anoctamin 1, calcium activated chloride channel affects expression ISO Orphenadrine affects the expression of ANO1 mRNA CTD PMID:23665939 NCBI chr 7:144,142,286...144,305,762
Ensembl chr 7:144,142,286...144,305,711
JBrowse link
G Anxa5 annexin A5 affects expression ISO Orphenadrine affects the expression of ANXA5 mRNA CTD PMID:23665939 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G App amyloid beta precursor protein affects expression ISO Orphenadrine affects the expression of APP mRNA CTD PMID:23665939 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Aqp9 aquaporin 9 affects expression ISO Orphenadrine affects the expression of AQP9 mRNA CTD PMID:23665939 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
JBrowse link
G Arhgap10 Rho GTPase activating protein 10 affects expression ISO Orphenadrine affects the expression of ARHGAP10 mRNA CTD PMID:23665939 NCBI chr 8:77,976,995...78,244,628
Ensembl chr 8:77,976,995...78,244,582
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 affects expression ISO Orphenadrine affects the expression of ARHGAP22 mRNA CTD PMID:23665939 NCBI chr14:32,935,952...33,091,893
Ensembl chr14:32,935,983...33,091,891
JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 affects expression ISO Orphenadrine affects the expression of ARHGEF10 mRNA CTD PMID:23665939 NCBI chr 8:14,956,405...15,051,085
Ensembl chr 8:14,961,663...15,051,085
JBrowse link
G Arhgef15 Rho guanine nucleotide exchange factor 15 affects expression ISO Orphenadrine affects the expression of ARHGEF15 mRNA CTD PMID:23665939 NCBI chr11:68,819,726...68,847,760
Ensembl chr11:68,833,981...68,848,306
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 affects expression ISO Orphenadrine affects the expression of ARMCX1 mRNA CTD PMID:23665939 NCBI chr  X:133,618,615...133,623,487
Ensembl chr  X:133,618,712...133,622,666
JBrowse link
G Arrdc2 arrestin domain containing 2 affects expression ISO Orphenadrine affects the expression of ARRDC2 mRNA CTD PMID:23665939 NCBI chr 8:71,287,773...71,293,173
Ensembl chr 8:71,287,773...71,292,364
JBrowse link
G Atf3 activating transcription factor 3 affects expression ISO Orphenadrine affects the expression of ATF3 mRNA CTD PMID:23665939 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 affects expression ISO Orphenadrine affects the expression of ATP2B2 mRNA CTD PMID:23665939 NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
JBrowse link
G Atrnl1 attractin like 1 affects expression ISO Orphenadrine affects the expression of ATRNL1 mRNA CTD PMID:23665939 NCBI chr19:57,599,248...58,121,775
Ensembl chr19:57,599,466...58,121,775
JBrowse link
G Azin2 antizyme inhibitor 2 affects expression ISO Orphenadrine affects the expression of AZIN2 mRNA CTD PMID:23665939 NCBI chr 4:128,824,026...128,856,250
Ensembl chr 4:128,824,026...128,856,235
JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 affects expression ISO Orphenadrine affects the expression of B3GNT9 mRNA CTD PMID:23665939 NCBI chr 8:105,979,270...105,981,895
Ensembl chr 8:105,979,270...105,981,785
JBrowse link
G B4galt6 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 affects expression ISO Orphenadrine affects the expression of B4GALT6 mRNA CTD PMID:23665939 NCBI chr18:20,817,656...20,879,461
Ensembl chr18:20,817,656...20,879,461
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression ISO Orphenadrine affects the expression of BAMBI mRNA CTD PMID:23665939 NCBI chr18:3,507,011...3,516,404
Ensembl chr18:3,507,923...3,516,404
JBrowse link
G Bbc3 BCL2 binding component 3 affects expression ISO Orphenadrine affects the expression of BBC3 mRNA CTD PMID:23665939 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130
JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 affects expression ISO Orphenadrine affects the expression of BCL6 mRNA CTD PMID:23665939 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
JBrowse link
G Bco2 beta-carotene oxygenase 2 affects expression ISO Orphenadrine affects the expression of BCO2 mRNA CTD PMID:23665939 NCBI chr 9:50,444,387...50,466,513
Ensembl chr 9:50,444,387...50,466,481
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 affects expression ISO Orphenadrine affects the expression of BHLHA15 mRNA CTD PMID:23665939 NCBI chr 5:144,127,104...144,131,259
Ensembl chr 5:144,127,104...144,131,259
JBrowse link
G Bicc1 BicC family RNA binding protein 1 affects expression ISO Orphenadrine affects the expression of BICC1 mRNA CTD PMID:23665939 NCBI chr10:70,758,660...70,995,581
Ensembl chr10:70,758,662...70,995,530
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression ISO Orphenadrine affects the expression of BMP4 mRNA CTD PMID:23665939 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Btbd7 BTB domain containing 7 affects expression ISO Orphenadrine affects the expression of BTBD7 mRNA CTD PMID:23665939 NCBI chr12:102,747,056...102,844,733
Ensembl chr12:102,747,056...102,844,730
JBrowse link
G C1qtnf2 C1q and tumor necrosis factor related protein 2 affects expression ISO Orphenadrine affects the expression of C1QTNF2 mRNA CTD PMID:23665939 NCBI chr11:43,364,984...43,382,485
Ensembl chr11:43,365,103...43,382,352
JBrowse link
G Calcrl calcitonin receptor-like affects expression ISO Orphenadrine affects the expression of CALCRL mRNA CTD PMID:23665939 NCBI chr 2:84,160,970...84,255,786
Ensembl chr 2:84,160,970...84,255,755
JBrowse link
G Car1 carbonic anhydrase 1 affects expression ISO Orphenadrine affects the expression of CA1 mRNA CTD PMID:23665939 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Car2 carbonic anhydrase 2 affects expression ISO Orphenadrine affects the expression of CA2 mRNA CTD PMID:23665939 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830
JBrowse link
G Car3 carbonic anhydrase 3 affects expression ISO Orphenadrine affects the expression of CA3 mRNA CTD PMID:23665939 NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
JBrowse link
G Card19 caspase recruitment domain family, member 19 affects expression ISO Orphenadrine affects the expression of CARD19 mRNA CTD PMID:23665939 NCBI chr13:49,356,426...49,369,471
Ensembl chr13:49,356,426...49,369,513
JBrowse link
G Casp2 caspase 2 affects expression ISO Orphenadrine affects the expression of CASP2 mRNA CTD PMID:23665939 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442
JBrowse link
G Cblc Casitas B-lineage lymphoma c affects expression ISO Orphenadrine affects the expression of CBLC mRNA CTD PMID:23665939 NCBI chr 7:19,513,643...19,530,734
Ensembl chr 7:19,512,806...19,530,734
JBrowse link
G Cbx4 chromobox 4 affects expression ISO Orphenadrine affects the expression of CBX4 mRNA CTD PMID:23665939 NCBI chr11:118,968,399...118,977,067
Ensembl chr11:118,968,399...118,977,047
JBrowse link
G Ccdc68 coiled-coil domain containing 68 affects expression ISO Orphenadrine affects the expression of CCDC68 mRNA CTD PMID:23665939 NCBI chr18:70,057,929...70,102,559
Ensembl chr18:70,058,497...70,102,555
JBrowse link
G Ccn1 cellular communication network factor 1 affects expression ISO Orphenadrine affects the expression of CCN1 mRNA CTD PMID:23665939 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Orphenadrine promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA] CTD PMID:23665939 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd2 cyclin D2 affects expression ISO Orphenadrine affects the expression of CCND2 mRNA CTD PMID:23665939 NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156
JBrowse link
G Cd24a CD24a antigen affects expression ISO Orphenadrine affects the expression of CD24 mRNA CTD PMID:23665939 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
JBrowse link
G Cd276 CD276 antigen affects expression ISO Orphenadrine affects the expression of CD276 mRNA CTD PMID:23665939 NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720
JBrowse link
G Cd36 CD36 molecule affects expression ISO Orphenadrine affects the expression of CD36 mRNA CTD PMID:23665939 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 affects expression ISO Orphenadrine affects the expression of CDC42EP1 mRNA CTD PMID:23665939 NCBI chr15:78,726,847...78,735,102
Ensembl chr15:78,726,824...78,735,097
JBrowse link
G Cdh3 cadherin 3 affects expression ISO Orphenadrine affects the expression of CDH3 mRNA CTD PMID:23665939 NCBI chr 8:107,237,484...107,283,543
Ensembl chr 8:107,237,523...107,283,929
JBrowse link
G Cdr2 cerebellar degeneration-related 2 affects expression ISO Orphenadrine affects the expression of CDR2 mRNA CTD PMID:23665939 NCBI chr 7:120,556,259...120,581,535
Ensembl chr 7:120,556,259...120,581,535
JBrowse link
G Ces2h carboxylesterase 2H affects expression ISO Orphenadrine affects the expression of CES2 mRNA CTD PMID:23665939 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cfap68 cilia and flagella associated protein 68 affects expression ISO Orphenadrine affects the expression of CFAP68 mRNA CTD PMID:23665939 NCBI chr 9:50,672,674...50,679,536
Ensembl chr 9:50,674,128...50,686,820
JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 affects expression ISO Orphenadrine affects the expression of CGREF1 mRNA CTD PMID:23665939 NCBI chr 5:31,090,487...31,102,771
Ensembl chr 5:31,090,487...31,102,935
JBrowse link
G Chmp4c charged multivesicular body protein 4C affects expression ISO Orphenadrine affects the expression of CHMP4C mRNA CTD PMID:23665939 NCBI chr 3:10,432,033...10,456,065
Ensembl chr 3:10,431,967...10,493,916
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A affects expression ISO Orphenadrine affects the expression of CIDEA mRNA CTD PMID:23665939 NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
JBrowse link
G Cish cytokine inducible SH2-containing protein affects expression ISO Orphenadrine affects the expression of CISH mRNA CTD PMID:23665939 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 affects expression ISO Orphenadrine affects the expression of CLCF1 mRNA CTD PMID:23665939 NCBI chr19:4,264,479...4,273,548
Ensembl chr19:4,264,292...4,273,544
JBrowse link
G Cldn23 claudin 23 affects expression ISO Orphenadrine affects the expression of CLDN23 mRNA CTD PMID:23665939 NCBI chr 8:36,291,863...36,293,713
Ensembl chr 8:36,291,866...36,293,713
JBrowse link
G Cndp1 carnosine dipeptidase 1 affects expression ISO Orphenadrine affects the expression of CNDP1 mRNA CTD PMID:23665939 NCBI chr18:84,628,509...84,668,359
Ensembl chr18:84,628,634...84,668,220
JBrowse link
G Col4a3 collagen, type IV, alpha 3 affects expression ISO Orphenadrine affects the expression of COL4A3 mRNA CTD PMID:23665939 NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1b, muscle affects expression ISO Orphenadrine affects the expression of CPT1B mRNA CTD PMID:23665939 NCBI chr15:89,300,608...89,310,065
Ensembl chr15:89,300,608...89,310,066
JBrowse link
G Crat carnitine acetyltransferase affects expression ISO Orphenadrine affects the expression of CRAT mRNA CTD PMID:23665939 NCBI chr 2:30,290,483...30,305,602
Ensembl chr 2:30,290,483...30,305,825
JBrowse link
G Crlf2 cytokine receptor-like factor 2 affects expression ISO Orphenadrine affects the expression of CRLF2 mRNA CTD PMID:23665939 NCBI chr 5:109,702,575...109,707,301
Ensembl chr 5:109,702,575...109,706,859
JBrowse link
G Cryab crystallin, alpha B affects expression ISO Orphenadrine affects the expression of CRYAB mRNA CTD PMID:23665939 NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936
JBrowse link
G Cryl1 crystallin, lambda 1 affects expression ISO Orphenadrine affects the expression of CRYL1 mRNA CTD PMID:23665939 NCBI chr14:57,512,491...57,635,940
Ensembl chr14:57,512,450...57,635,986
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 affects expression ISO Orphenadrine affects the expression of CSMD1 mRNA CTD PMID:23665939 NCBI chr 8:15,942,538...17,586,908
Ensembl chr 8:15,942,537...17,585,602
JBrowse link
G Csrnp1 cysteine-serine-rich nuclear protein 1 affects expression ISO Orphenadrine affects the expression of CSRNP1 mRNA CTD PMID:23665939 NCBI chr 9:119,800,229...119,813,808
Ensembl chr 9:119,800,229...119,813,724
JBrowse link
G Cst9 cystatin 9 affects expression ISO Orphenadrine affects the expression of CST9L mRNA CTD PMID:23665939 NCBI chr 2:148,677,067...148,680,657
Ensembl chr 2:148,677,067...148,680,658
JBrowse link
G Ctps1 cytidine 5'-triphosphate synthase 1 affects expression ISO Orphenadrine affects the expression of CTPS1 mRNA CTD PMID:23665939 NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473
JBrowse link
G Ctrb1 chymotrypsinogen B1 affects expression ISO Orphenadrine affects the expression of CTRB mRNA CTD PMID:23665939 NCBI chr 8:112,413,142...112,417,642
Ensembl chr 8:112,413,151...112,417,642
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression
ISO [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA
Orphenadrine affects the expression of CYP1A1 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP1A2 protein
Orphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CTD PMID:9241656 PMID:18493746 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP2B6 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2B6 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2B6 protein
CTD PMID:9241656 PMID:12464242 PMID:15306208 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 affects expression
multiple interactions
ISO Orphenadrine affects the expression of CYP2B2 mRNA
[Orphenadrine co-treated with Phenobarbital] affects the expression of CYP2B2 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 affects expression ISO Orphenadrine affects the expression of CYP2C24 mRNA CTD PMID:23665939 NCBI chr19:38,995,384...39,031,134
Ensembl chr19:38,995,463...39,031,137
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
ISO Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
Orphenadrine results in decreased activity of CYP2E1 protein
CTD PMID:9241656 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B affects expression ISO Orphenadrine affects the expression of CYP4A1 mRNA CTD PMID:23665939 NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects expression ISO Orphenadrine affects the expression of CYP4B1 mRNA CTD PMID:23665939 NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 affects expression ISO Orphenadrine affects the expression of CYP7A1 mRNA CTD PMID:23665939 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 affects expression ISO Orphenadrine affects the expression of CYP8B1 mRNA CTD PMID:23665939 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Cystm1 cysteine-rich transmembrane module containing 1 affects expression ISO Orphenadrine affects the expression of CYSTM1 mRNA CTD PMID:23665939 NCBI chr18:36,481,677...36,536,032
Ensembl chr18:36,475,573...36,536,150
JBrowse link
G Cyyr1 cysteine and tyrosine-rich protein 1 affects expression ISO Orphenadrine affects the expression of CYYR1 mRNA CTD PMID:23665939 NCBI chr16:85,247,245...85,347,793
Ensembl chr16:85,218,421...85,350,285
JBrowse link
G Dact2 dishevelled-binding antagonist of beta-catenin 2 affects expression ISO Orphenadrine affects the expression of DACT2 mRNA CTD PMID:23665939 NCBI chr17:14,415,492...14,424,595
Ensembl chr17:14,415,314...14,424,566
JBrowse link
G Defb36 defensin beta 36 affects expression ISO Orphenadrine affects the expression of DEFB36 mRNA CTD PMID:23665939 NCBI chr 2:152,446,247...152,454,649
Ensembl chr 2:152,446,247...152,454,649
JBrowse link
G Dip2a disco interacting protein 2 homolog A affects expression ISO Orphenadrine affects the expression of DIP2A mRNA CTD PMID:23665939 NCBI chr10:76,098,581...76,181,194
Ensembl chr10:76,095,263...76,181,125
JBrowse link
G Dll1 delta like canonical Notch ligand 1 affects expression ISO Orphenadrine affects the expression of DLL1 mRNA CTD PMID:23665939 NCBI chr17:15,587,616...15,597,275
Ensembl chr17:15,587,616...15,597,134
JBrowse link
G Dnhd1 dynein heavy chain domain 1 affects expression ISO Orphenadrine affects the expression of DNHD1 mRNA CTD PMID:23665939 NCBI chr 7:105,299,983...105,371,007
Ensembl chr 7:105,300,034...105,371,006
JBrowse link
G Dpp6 dipeptidylpeptidase 6 affects expression ISO Orphenadrine affects the expression of DPP6 mRNA CTD PMID:23665939 NCBI chr 5:27,022,355...27,932,498
Ensembl chr 5:27,022,201...27,932,503
JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 affects expression ISO Orphenadrine affects the expression of DRAM1 mRNA CTD PMID:23665939 NCBI chr10:88,158,663...88,200,218
Ensembl chr10:88,158,666...88,214,942
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression ISO Orphenadrine affects the expression of DUSP1 mRNA CTD PMID:23665939 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp10 dual specificity phosphatase 10 affects expression ISO Orphenadrine affects the expression of DUSP10 mRNA CTD PMID:23665939 NCBI chr 1:183,766,575...183,807,833
Ensembl chr 1:183,745,499...183,807,833
JBrowse link
G Dusp13b dual specificity phosphatase 13B affects expression ISO Orphenadrine affects the expression of DUSP13B mRNA CTD PMID:23665939 NCBI chr14:21,783,463...21,792,947
Ensembl chr14:21,783,462...21,792,947
JBrowse link
G Dusp16 dual specificity phosphatase 16 affects expression ISO Orphenadrine affects the expression of DUSP16 mRNA CTD PMID:23665939 NCBI chr 6:134,692,431...134,769,687
Ensembl chr 6:134,692,431...134,769,588
JBrowse link
G Dusp8 dual specificity phosphatase 8 affects expression ISO Orphenadrine affects the expression of DUSP8 mRNA CTD PMID:23665939 NCBI chr 7:141,633,224...141,649,799
Ensembl chr 7:141,633,227...141,649,580
JBrowse link
G Eeig1 estrogen-induced osteoclastogenesis regulator 1 affects expression ISO Orphenadrine affects the expression of EEIG1 mRNA CTD PMID:23665939 NCBI chr 2:32,425,344...32,459,763
Ensembl chr 2:32,425,344...32,459,768
JBrowse link
G Eeig2 EEIG family member 2 affects expression ISO Orphenadrine affects the expression of EEIG2 mRNA CTD PMID:23665939 NCBI chr 3:108,878,313...108,935,588
Ensembl chr 3:108,878,313...108,934,923
JBrowse link
G Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 affects expression ISO Orphenadrine affects the expression of EFEMP1 mRNA CTD PMID:23665939 NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 affects expression ISO Orphenadrine affects the expression of EGLN3 mRNA CTD PMID:23665939 NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646
JBrowse link
G Egr1 early growth response 1 affects expression ISO Orphenadrine affects the expression of EGR1 mRNA CTD PMID:23665939 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Emilin1 elastin microfibril interfacer 1 affects expression ISO Orphenadrine affects the expression of EMILIN1 mRNA CTD PMID:23665939 NCBI chr 5:31,070,729...31,078,623
Ensembl chr 5:31,070,746...31,078,621
JBrowse link
G Epha2 Eph receptor A2 affects expression ISO Orphenadrine affects the expression of EPHA2 mRNA CTD PMID:23665939 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695
JBrowse link
G Ephb4 Eph receptor B4 affects expression ISO Orphenadrine affects the expression of EPHB4 mRNA CTD PMID:23665939 NCBI chr 5:137,348,371...137,372,784
Ensembl chr 5:137,348,371...137,376,931
JBrowse link
G Eri2 exoribonuclease 2 affects expression ISO Orphenadrine affects the expression of ERI2 mRNA CTD PMID:23665939 NCBI chr 7:119,383,049...119,393,283
Ensembl chr 7:119,367,902...119,393,281
JBrowse link
G F8 coagulation factor VIII affects expression ISO Orphenadrine affects the expression of F8 mRNA CTD PMID:23665939 NCBI chr  X:74,213,950...74,426,342
Ensembl chr  X:74,216,321...74,426,221
JBrowse link
G Fam89a family with sequence similarity 89, member A affects expression ISO Orphenadrine affects the expression of FAM89A mRNA CTD PMID:23665939 NCBI chr 8:125,466,996...125,478,605
Ensembl chr 8:125,466,996...125,478,571
JBrowse link
G Fbxo27 F-box protein 27 affects expression ISO Orphenadrine affects the expression of FBXO27 mRNA CTD PMID:23665939 NCBI chr 7:28,392,205...28,398,763
Ensembl chr 7:28,392,274...28,398,763
JBrowse link
G Fer1l5 fer-1 like family member 5 affects expression ISO Orphenadrine affects the expression of FER1L5 mRNA CTD PMID:23665939 NCBI chr 1:36,411,264...36,461,191
Ensembl chr 1:36,411,372...36,461,191
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 affects expression ISO Orphenadrine affects the expression of FGD5 mRNA CTD PMID:23665939 NCBI chr 6:91,955,809...92,052,986
Ensembl chr 6:91,955,859...92,052,985
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 affects expression ISO Orphenadrine affects the expression of FLT1 mRNA CTD PMID:23665939 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821
JBrowse link
G Flt4 FMS-like tyrosine kinase 4 affects expression ISO Orphenadrine affects the expression of FLT4 mRNA CTD PMID:23665939 NCBI chr11:49,500,506...49,543,566
Ensembl chr11:49,500,090...49,543,566
JBrowse link
G Fmo1 flavin containing monooxygenase 1 affects expression ISO Orphenadrine affects the expression of FMO1 mRNA CTD PMID:23665939 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression ISO Orphenadrine affects the expression of FNDC5 mRNA CTD PMID:23665939 NCBI chr 4:129,030,672...129,038,386
Ensembl chr 4:129,030,477...129,038,386
JBrowse link
G Fst follistatin affects expression ISO Orphenadrine affects the expression of FST mRNA CTD PMID:23665939 NCBI chr13:114,588,798...114,595,522
Ensembl chr13:114,588,826...114,595,487
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma affects expression ISO Orphenadrine affects the expression of GADD45G mRNA CTD PMID:23665939 NCBI chr13:52,000,711...52,002,511
Ensembl chr13:52,000,714...52,002,504
JBrowse link
G Gdf11 growth differentiation factor 11 affects expression ISO Orphenadrine affects the expression of GDF11 mRNA CTD PMID:23665939 NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 affects expression ISO Orphenadrine affects the expression of GGT1 mRNA CTD PMID:23665939 NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034
JBrowse link
G Gimd1 GIMAP family P-loop NTPase domain containing 1 affects expression ISO Orphenadrine affects the expression of GIMD1 mRNA CTD PMID:23665939 NCBI chr 3:132,335,607...132,353,543
Ensembl chr 3:132,335,581...132,351,112
JBrowse link
G Gipc2 GIPC PDZ domain containing family, member 2 affects expression ISO Orphenadrine affects the expression of GIPC2 mRNA CTD PMID:23665939 NCBI chr 3:151,799,476...151,871,537
Ensembl chr 3:151,799,170...151,871,867
JBrowse link
G Gmip Gem-interacting protein affects expression ISO Orphenadrine affects the expression of GMIP mRNA CTD PMID:23665939 NCBI chr 8:70,260,912...70,274,520
Ensembl chr 8:70,261,329...70,274,520
JBrowse link
G Gna14 guanine nucleotide binding protein, alpha 14 affects expression ISO Orphenadrine affects the expression of GNA14 mRNA CTD PMID:23665939 NCBI chr19:16,413,031...16,590,706
Ensembl chr19:16,413,126...16,588,184
JBrowse link
G Gnai1 G protein subunit alpha i1 affects expression ISO Orphenadrine affects the expression of GNAI1 mRNA CTD PMID:23665939 NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 affects expression ISO Orphenadrine affects the expression of GPAT3 mRNA CTD PMID:23665939 NCBI chr 5:100,994,095...101,046,968
Ensembl chr 5:100,993,579...101,046,968
JBrowse link
G Gpr17 G protein-coupled receptor 17 affects expression ISO Orphenadrine affects the expression of GPR17 mRNA CTD PMID:23665939 NCBI chr18:32,076,052...32,082,925
Ensembl chr18:32,076,050...32,082,689
JBrowse link
G Gpx2 glutathione peroxidase 2 affects expression
multiple interactions
ISO Orphenadrine affects the expression of GPX2 mRNA
[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA; [Phenobarbital co-treated with Orphenadrine] affects the expression of GPX2 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) affects expression ISO Orphenadrine affects the expression of GRIA3 mRNA CTD PMID:23665939 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478
JBrowse link
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) affects expression ISO Orphenadrine affects the expression of GRIK5 mRNA CTD PMID:23665939 NCBI chr 7:24,709,274...24,775,421
Ensembl chr 7:24,709,274...24,771,771
JBrowse link
G Gse1 genetic suppressor element 1, coiled-coil protein affects expression ISO Orphenadrine affects the expression of GSE1 mRNA CTD PMID:23665939 NCBI chr 8:120,955,233...121,308,122
Ensembl chr 8:120,955,195...121,308,129
JBrowse link
G Gstm4 glutathione S-transferase, mu 4 affects expression ISO Orphenadrine affects the expression of GSTM4 mRNA CTD PMID:23665939 NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
affects expression
ISO [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA; [Phenobarbital co-treated with Orphenadrine] affects the expression of GSTM3 mRNA
Orphenadrine affects the expression of GSTM3 mRNA
CTD PMID:23665939 PMID:23665940 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 affects expression ISO Orphenadrine affects the expression of GSTP1 mRNA CTD PMID:23665939 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Hal histidine ammonia lyase affects expression ISO Orphenadrine affects the expression of HAL mRNA CTD PMID:23665939 NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
JBrowse link
G Hebp2 heme binding protein 2 affects expression ISO Orphenadrine affects the expression of HEBP2 mRNA CTD PMID:23665939 NCBI chr10:18,415,871...18,421,824
Ensembl chr10:18,415,246...18,421,824
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression ISO Orphenadrine affects the expression of HES1 mRNA CTD PMID:23665939 NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614
JBrowse link
G Hgf hepatocyte growth factor affects expression ISO Orphenadrine affects the expression of HGF mRNA CTD PMID:23665939 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hid1 HID1 domain containing affects expression ISO Orphenadrine affects the expression of HID1 mRNA CTD PMID:23665939 NCBI chr11:115,238,531...115,261,087
Ensembl chr11:115,238,533...115,258,582
JBrowse link
G Hspa1a heat shock protein 1A affects expression ISO Orphenadrine affects the expression of HSPA1A mRNA CTD PMID:23665939 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1b heat shock protein 1B affects expression ISO Orphenadrine affects the expression of HSPA1B mRNA CTD PMID:23665939 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Hycc1 hyccin PI4KA lipid kinase complex subunit 1 affects expression ISO Orphenadrine affects the expression of HYCC1 mRNA CTD PMID:23665939 NCBI chr 5:24,120,274...24,235,694
Ensembl chr 5:24,120,274...24,235,688
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein affects expression ISO Orphenadrine affects the expression of ID1 mRNA CTD PMID:23665939 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
JBrowse link
G Id3 inhibitor of DNA binding 3 affects expression ISO Orphenadrine affects the expression of ID3 mRNA CTD PMID:23665939 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 affects expression ISO Orphenadrine affects the expression of IDO2 mRNA CTD PMID:23665939 NCBI chr 8:25,021,908...25,066,430
Ensembl chr 8:25,021,908...25,066,349
JBrowse link
G Ier5 immediate early response 5 affects expression ISO Orphenadrine affects the expression of IER5 mRNA CTD PMID:23665939 NCBI chr 1:154,972,113...154,975,382
Ensembl chr 1:154,972,107...154,975,382
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression ISO Orphenadrine affects the expression of IGFBP1 mRNA CTD PMID:23665939 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Ihh Indian hedgehog affects expression ISO Orphenadrine affects the expression of IHH mRNA CTD PMID:23665939 NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
JBrowse link
G Ikbkg inhibitor of kappaB kinase gamma affects expression ISO Orphenadrine affects the expression of IKBKG mRNA CTD PMID:23665939 NCBI chr  X:73,436,883...73,498,013
Ensembl chr  X:73,436,896...73,497,460
JBrowse link
G Il17rb interleukin 17 receptor B affects expression ISO Orphenadrine affects the expression of IL17RB mRNA CTD PMID:23665939 NCBI chr14:29,718,125...29,730,853
Ensembl chr14:29,718,092...29,730,853
JBrowse link
G Il33 interleukin 33 affects expression ISO Orphenadrine affects the expression of IL33 mRNA CTD PMID:23665939 NCBI chr19:29,902,513...29,938,118
Ensembl chr19:29,902,514...29,938,118
JBrowse link
G Inf2 inverted formin, FH2 and WH2 domain containing affects expression ISO Orphenadrine affects the expression of INF2 mRNA CTD PMID:23665939 NCBI chr12:112,555,121...112,581,991
Ensembl chr12:112,555,218...112,581,991
JBrowse link
G Ip6k2 inositol hexaphosphate kinase 2 affects expression ISO Orphenadrine affects the expression of IP6K2 mRNA CTD PMID:23665939 NCBI chr 9:108,660,928...108,683,532
Ensembl chr 9:108,660,995...108,683,536
JBrowse link
G Irf7 interferon regulatory factor 7 affects expression ISO Orphenadrine affects the expression of IRF7 mRNA CTD PMID:23665939 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
JBrowse link
G Irx1 Iroquois homeobox 1 affects expression ISO Orphenadrine affects the expression of IRX1 mRNA CTD PMID:23665939 NCBI chr13:72,106,351...72,111,842
Ensembl chr13:72,106,040...72,111,842
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO Orphenadrine affects the expression of ISG15 mRNA CTD PMID:23665939 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253
JBrowse link
G Itgb3 integrin beta 3 affects expression ISO Orphenadrine affects the expression of ITGB3 mRNA CTD PMID:23665939 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Jun jun proto-oncogene affects expression ISO Orphenadrine affects the expression of JUN mRNA CTD PMID:23665939 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene affects expression ISO Orphenadrine affects the expression of JUNB mRNA CTD PMID:23665939 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 affects expression ISO Orphenadrine affects the expression of KANK2 mRNA CTD PMID:23665939 NCBI chr 9:21,678,069...21,709,842
Ensembl chr 9:21,678,080...21,710,040
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 affects expression ISO Orphenadrine affects the expression of KCNJ15 mRNA CTD PMID:23665939 NCBI chr16:95,058,417...95,101,119
Ensembl chr16:95,058,417...95,101,119
JBrowse link
G Kcnk5 potassium channel, subfamily K, member 5 affects expression ISO Orphenadrine affects the expression of KCNK5 mRNA CTD PMID:23665939 NCBI chr14:20,190,125...20,231,850
Ensembl chr14:20,190,125...20,231,877
JBrowse link
G Klf10 Kruppel-like transcription factor 10 affects expression ISO Orphenadrine affects the expression of KLF10 mRNA CTD PMID:23665939 NCBI chr15:38,291,702...38,300,950
Ensembl chr15:38,291,707...38,300,950
JBrowse link
G Klhl21 kelch-like 21 affects expression ISO Orphenadrine affects the expression of KLHL21 mRNA CTD PMID:23665939 NCBI chr 4:152,093,348...152,102,134
Ensembl chr 4:152,093,260...152,102,137
JBrowse link
G Kmo kynurenine 3-monooxygenase affects expression ISO Orphenadrine affects the expression of KMO mRNA CTD PMID:23665939 NCBI chr 1:175,459,759...175,488,419
Ensembl chr 1:175,447,947...175,489,682
JBrowse link
G Krt10 keratin 10 affects expression ISO Orphenadrine affects the expression of KRT10 mRNA CTD PMID:23665939 NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190
JBrowse link
G Krt8 keratin 8 affects expression ISO Orphenadrine affects the expression of KRT8 mRNA CTD PMID:23665939 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
JBrowse link
G Lag3 lymphocyte-activation gene 3 affects expression ISO Orphenadrine affects the expression of LAG3 mRNA CTD PMID:23665939 NCBI chr 6:124,881,322...124,888,668
Ensembl chr 6:124,881,324...124,888,668
JBrowse link
G Lekr1 leucine, glutamate and lysine rich 1 affects expression ISO Orphenadrine affects the expression of LEKR1 mRNA CTD PMID:23665939 NCBI chr 3:65,566,960...65,743,948
Ensembl chr 3:65,573,649...65,738,776
JBrowse link
G Lgals2 lectin, galactose-binding, soluble 2 affects expression ISO Orphenadrine affects the expression of LGALS2 mRNA CTD PMID:23665939 NCBI chr15:78,735,060...78,739,729
Ensembl chr15:78,735,060...78,739,729
JBrowse link
G Lhx8 LIM homeobox protein 8 affects expression ISO Orphenadrine affects the expression of LHX8 mRNA CTD PMID:23665939 NCBI chr 3:154,011,925...154,036,190
Ensembl chr 3:154,011,931...154,036,296
JBrowse link
G Lilrb4b leukocyte immunoglobulin-like receptor, subfamily B, member 4B affects expression ISO Orphenadrine affects the expression of LILRB4 mRNA CTD PMID:23665939 NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component affects expression ISO Orphenadrine affects the expression of LIN7A mRNA CTD PMID:23665939 NCBI chr10:107,107,410...107,261,007
Ensembl chr10:107,107,547...107,257,335
JBrowse link
G Lmod2 leiomodin 2 (cardiac) affects expression ISO Orphenadrine affects the expression of LMOD2 mRNA CTD PMID:23665939 NCBI chr 6:24,597,770...24,605,413
Ensembl chr 6:24,597,761...24,605,413
JBrowse link
G Loxl4 lysyl oxidase-like 4 affects expression ISO Orphenadrine affects the expression of LOXL4 mRNA CTD PMID:23665939 NCBI chr19:42,580,718...42,601,326
Ensembl chr19:42,582,421...42,601,252
JBrowse link
G Lpcat4 lysophosphatidylcholine acyltransferase 4 affects expression ISO Orphenadrine affects the expression of LPCAT4 mRNA CTD PMID:23665939 NCBI chr 2:112,070,186...112,077,456
Ensembl chr 2:112,069,813...112,077,456
JBrowse link
G Lpin2 lipin 2 affects expression ISO Orphenadrine affects the expression of LPIN2 mRNA CTD PMID:23665939 NCBI chr17:71,490,527...71,556,813
Ensembl chr17:71,489,555...71,556,812
JBrowse link
G Lpl lipoprotein lipase affects expression ISO Orphenadrine affects the expression of LPL mRNA CTD PMID:23665939 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Lrrn4 leucine rich repeat neuronal 4 affects expression ISO Orphenadrine affects the expression of LRRN4 mRNA CTD PMID:23665939 NCBI chr 2:132,710,436...132,735,930
Ensembl chr 2:132,710,225...132,722,811
JBrowse link
G Ltc4s leukotriene C4 synthase affects expression ISO Orphenadrine affects the expression of LTC4S mRNA CTD PMID:23665939 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
G Mafb MAF bZIP transcription factor B affects expression ISO Orphenadrine affects the expression of MAFB mRNA CTD PMID:23665939 NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985
JBrowse link
G Magee1 MAGE family member E1 affects expression ISO Orphenadrine affects the expression of MAGEE1 mRNA CTD PMID:23665939 NCBI chr  X:104,163,984...104,167,567
Ensembl chr  X:104,163,984...104,167,533
JBrowse link
G Map1s microtubule-associated protein 1S affects expression ISO Orphenadrine affects the expression of MAP1S mRNA CTD PMID:23665939 NCBI chr 8:71,358,618...71,370,173
Ensembl chr 8:71,358,576...71,370,173
JBrowse link
G Map4k2 mitogen-activated protein kinase kinase kinase kinase 2 affects expression ISO Orphenadrine affects the expression of MAP4K2 mRNA CTD PMID:23665939 NCBI chr19:6,391,023...6,405,649
Ensembl chr19:6,391,165...6,405,645
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 affects expression ISO Orphenadrine affects the expression of MAP4K4 mRNA CTD PMID:23665939 NCBI chr 1:39,939,806...40,065,470
Ensembl chr 1:39,940,073...40,065,470
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 affects expression ISO Orphenadrine affects the expression of MAPK12 mRNA CTD PMID:23665939 NCBI chr15:89,014,787...89,025,270
Ensembl chr15:89,014,787...89,024,906
JBrowse link
G Matn4 matrilin 4 affects expression ISO Orphenadrine affects the expression of MATN4 mRNA CTD PMID:23665939 NCBI chr 2:164,231,313...164,247,080
Ensembl chr 2:164,231,313...164,247,080
JBrowse link
G Mcam melanoma cell adhesion molecule affects expression ISO Orphenadrine affects the expression of MCAM mRNA CTD PMID:23665939 NCBI chr 9:44,045,958...44,054,024
Ensembl chr 9:44,045,766...44,054,024
JBrowse link
G Metap1d methionyl aminopeptidase type 1D (mitochondrial) affects expression ISO Orphenadrine affects the expression of METAP1D mRNA CTD PMID:23665939 NCBI chr 2:71,283,625...71,355,538
Ensembl chr 2:71,283,620...71,355,538
JBrowse link
G Mex3b mex3 RNA binding family member B affects expression ISO Orphenadrine affects the expression of MEX3B mRNA CTD PMID:23665939 NCBI chr 7:82,516,541...82,520,784
Ensembl chr 7:82,516,541...82,520,723
JBrowse link
G Mex3d mex3 RNA binding family member D affects expression ISO Orphenadrine affects the expression of MEX3D mRNA CTD PMID:23665939 NCBI chr10:80,216,189...80,223,485
Ensembl chr10:80,216,189...80,223,493
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing affects expression ISO Orphenadrine affects the expression of MFGE8 mRNA CTD PMID:23665939 NCBI chr 7:78,783,516...78,798,808
Ensembl chr 7:78,783,516...78,798,808
JBrowse link
G Mid1 midline 1 affects expression ISO Orphenadrine affects the expression of MID1 mRNA CTD PMID:23665939 NCBI chr  X:168,468,178...168,773,692
Ensembl chr  X:168,468,195...168,773,794
JBrowse link
G Mid1ip1 Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) affects expression ISO Orphenadrine affects the expression of MID1IP1 mRNA CTD PMID:23665939 NCBI chr  X:10,583,604...10,585,941
Ensembl chr  X:10,581,252...10,585,929
JBrowse link
G Midn midnolin affects expression ISO Orphenadrine affects the expression of MIDN mRNA CTD PMID:23665939 NCBI chr10:79,984,106...79,994,202
Ensembl chr10:79,984,106...79,994,202
JBrowse link
G Mknk2 MAP kinase-interacting serine/threonine kinase 2 affects expression ISO Orphenadrine affects the expression of MKNK2 mRNA CTD PMID:23665939 NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946
JBrowse link
G Mlxip MLX interacting protein affects expression ISO Orphenadrine affects the expression of MLXIP mRNA CTD PMID:23665939 NCBI chr 5:123,532,438...123,595,998
Ensembl chr 5:123,532,861...123,595,995
JBrowse link
G Mmd monocyte to macrophage differentiation-associated affects expression ISO Orphenadrine affects the expression of MMD mRNA CTD PMID:23665939 NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415
JBrowse link
G Mmp12 matrix metallopeptidase 12 affects expression ISO Orphenadrine affects the expression of MMP12 mRNA CTD PMID:23665939 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mmp15 matrix metallopeptidase 15 affects expression ISO Orphenadrine affects the expression of MMP15 mRNA CTD PMID:23665939 NCBI chr 8:96,078,924...96,100,921
Ensembl chr 8:96,078,896...96,101,708
JBrowse link
G Mras muscle and microspikes RAS affects expression ISO Orphenadrine affects the expression of MRAS mRNA CTD PMID:23665939 NCBI chr 9:99,267,473...99,319,505
Ensembl chr 9:99,267,473...99,319,434
JBrowse link
G Mroh2a maestro heat-like repeat family member 2A affects expression ISO Orphenadrine affects the expression of MROH2A mRNA CTD PMID:23665939 NCBI chr 1:88,154,713...88,190,011
Ensembl chr 1:88,154,708...88,190,011
JBrowse link
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) affects expression ISO Orphenadrine affects the expression of MST1R mRNA CTD PMID:23665939 NCBI chr 9:107,784,057...107,797,582
Ensembl chr 9:107,784,072...107,797,582
JBrowse link
G Mtmr7 myotubularin related protein 7 affects expression ISO Orphenadrine affects the expression of MTMR7 mRNA CTD PMID:23665939 NCBI chr 8:41,003,184...41,088,210
Ensembl chr 8:41,004,136...41,087,840
JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 affects expression ISO Orphenadrine affects the expression of MTSS2 mRNA CTD PMID:23665939 NCBI chr 8:111,447,718...111,468,032
Ensembl chr 8:111,448,108...111,468,032
JBrowse link
G Mybph myosin binding protein H affects expression ISO Orphenadrine affects the expression of MYBPH mRNA CTD PMID:23665939 NCBI chr 1:134,121,159...134,128,975
Ensembl chr 1:134,121,186...134,128,970
JBrowse link
G Mypop Myb-related transcription factor, partner of profilin affects expression ISO Orphenadrine affects the expression of MYPOP mRNA CTD PMID:23665939 NCBI chr 7:18,725,230...18,735,691
Ensembl chr 7:18,725,170...18,735,691
JBrowse link
G Myrf myelin regulatory factor affects expression ISO Orphenadrine affects the expression of MYRF mRNA CTD PMID:23665939 NCBI chr19:10,185,635...10,218,134
Ensembl chr19:10,185,636...10,218,112
JBrowse link
G Nat8f2 N-acetyltransferase 8 (GCN5-related) family member 2 affects expression ISO Orphenadrine affects the expression of NAT8F2 mRNA CTD PMID:23665939 NCBI chr 6:85,842,404...85,846,119
Ensembl chr 6:85,842,404...85,846,140
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H affects expression ISO Orphenadrine affects the expression of NCAPH mRNA CTD PMID:23665939 NCBI chr 2:126,945,729...126,975,857
Ensembl chr 2:126,945,729...126,975,874
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 affects expression ISO Orphenadrine affects the expression of NCOA7 mRNA CTD PMID:23665939 NCBI chr10:30,521,578...30,683,401
Ensembl chr10:30,504,995...30,679,322
JBrowse link
G Nefh neurofilament, heavy polypeptide affects expression ISO Orphenadrine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 affects expression ISO Orphenadrine affects the expression of NEURL3 mRNA CTD PMID:23665939 NCBI chr 1:36,303,683...36,313,755
Ensembl chr 1:36,303,678...36,313,760
JBrowse link
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta affects expression ISO Orphenadrine affects the expression of NFKBIZ mRNA CTD PMID:23665939 NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262
JBrowse link
G Nhsl3 NHS like 3 affects expression ISO Orphenadrine affects the expression of NHSL3 mRNA CTD PMID:23665939 NCBI chr 4:129,113,371...129,155,194
Ensembl chr 4:129,113,371...129,155,197
JBrowse link
G Ninj2 ninjurin 2 affects expression ISO Orphenadrine affects the expression of NINJ2 mRNA CTD PMID:23665939 NCBI chr 6:120,070,315...120,177,300
Ensembl chr 6:120,070,311...120,177,300
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression ISO Orphenadrine affects the expression of NIPAL2 mRNA CTD PMID:23665939 NCBI chr15:34,572,942...34,679,739
Ensembl chr15:34,572,945...34,679,358
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 affects expression ISO Orphenadrine affects the expression of NLRC4 mRNA CTD PMID:23665939 NCBI chr17:74,733,254...74,766,140
Ensembl chr17:74,732,433...74,766,137
JBrowse link
G Noct nocturnin affects expression ISO Orphenadrine affects the expression of NOCT mRNA CTD PMID:23665939 NCBI chr 3:51,131,868...51,159,075
Ensembl chr 3:51,131,868...51,159,065
JBrowse link
G Nos1ap nitric oxide synthase 1 (neuronal) adaptor protein affects expression ISO Orphenadrine affects the expression of NOS1AP mRNA CTD PMID:23665939 NCBI chr 1:170,143,039...170,417,371
Ensembl chr 1:170,130,237...170,417,430
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell affects expression ISO Orphenadrine affects the expression of NOS3 mRNA CTD PMID:23665939 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Npy neuropeptide Y affects expression ISO Orphenadrine affects the expression of NPY mRNA CTD PMID:23665939 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 affects expression ISO Orphenadrine affects the expression of NR1D1 mRNA CTD PMID:23665939 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159
JBrowse link
G Nrep neuronal regeneration related protein affects expression ISO Orphenadrine affects the expression of NREP mRNA CTD PMID:23665939 NCBI chr18:33,570,072...33,597,444
Ensembl chr18:33,570,072...33,597,082
JBrowse link
G Nrg1 neuregulin 1 affects expression ISO Orphenadrine affects the expression of NRG1 mRNA CTD PMID:23665939 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Nrxn1 neurexin I affects expression ISO Orphenadrine affects the expression of NRXN1 mRNA CTD PMID:23665939 NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499
JBrowse link
G Nupr1 nuclear protein transcription regulator 1 affects expression ISO Orphenadrine affects the expression of NUPR1 mRNA CTD PMID:23665939 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033
JBrowse link
G Oat ornithine aminotransferase affects expression ISO Orphenadrine affects the expression of OAT mRNA CTD PMID:23665939 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Ogn osteoglycin affects expression ISO Orphenadrine affects the expression of OGN mRNA CTD PMID:23665939 NCBI chr13:49,761,491...49,777,977
Ensembl chr13:49,761,522...49,777,977
JBrowse link
G Omd osteomodulin affects expression ISO Orphenadrine affects the expression of OMD mRNA CTD PMID:23665939 NCBI chr13:49,735,938...49,746,088
Ensembl chr13:49,735,938...49,746,298
JBrowse link
G Or2y1 olfactory receptor family 2 subfamily Y member 1 affects expression ISO Orphenadrine affects the expression of OR2Y1I mRNA CTD PMID:23665939 NCBI chr11:49,385,362...49,386,291
Ensembl chr11:49,379,897...49,388,323
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 affects expression ISO Orphenadrine affects the expression of OSGIN1 mRNA CTD PMID:23665939 NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995
JBrowse link
G P3h2 prolyl 3-hydroxylase 2 affects expression ISO Orphenadrine affects the expression of P3H2 mRNA CTD PMID:23665939 NCBI chr16:25,778,034...25,924,563
Ensembl chr16:25,778,038...25,924,534
JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) affects expression ISO Orphenadrine affects the expression of P3H4 mRNA CTD PMID:23665939 NCBI chr11:100,299,293...100,305,542
Ensembl chr11:100,299,282...100,305,662
JBrowse link
G Panx2 pannexin 2 affects expression ISO Orphenadrine affects the expression of PANX2 mRNA CTD PMID:23665939 NCBI chr15:88,941,797...88,957,769
Ensembl chr15:88,943,937...88,957,770
JBrowse link
G Pcdh12 protocadherin 12 affects expression ISO Orphenadrine affects the expression of PCDH12 mRNA CTD PMID:23665939 NCBI chr18:38,400,145...38,417,454
Ensembl chr18:38,400,142...38,417,455
JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 affects expression ISO Orphenadrine affects the expression of PCP4L1 mRNA CTD PMID:23665939 NCBI chr 1:171,000,833...171,023,837
Ensembl chr 1:171,000,831...171,023,837
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 affects expression ISO Orphenadrine affects the expression of PCSK9 mRNA CTD PMID:23665939 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526
JBrowse link
G Pde5a phosphodiesterase 5A, cGMP-specific affects expression ISO Orphenadrine affects the expression of PDE5A mRNA CTD PMID:23665939 NCBI chr 3:122,522,822...122,653,023
Ensembl chr 3:122,522,596...122,653,023
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 affects expression ISO Orphenadrine affects the expression of PDK4 mRNA CTD PMID:23665939 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link
G Pdpn podoplanin affects expression ISO Orphenadrine affects the expression of PDPN mRNA CTD PMID:23665939 NCBI chr 4:142,993,979...143,026,134
Ensembl chr 4:142,994,001...143,026,134
JBrowse link
G Per2 period circadian clock 2 affects expression ISO Orphenadrine affects the expression of PER2 mRNA CTD PMID:23665939 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046
JBrowse link
G Pfkm phosphofructokinase, muscle affects expression ISO Orphenadrine affects the expression of PFKM mRNA CTD PMID:23665939 NCBI chr15:97,990,470...98,030,328
Ensembl chr15:97,990,470...98,030,332
JBrowse link
G Phlda2 pleckstrin homology like domain, family A, member 2 affects expression ISO Orphenadrine affects the expression of PHLDA2 mRNA CTD PMID:23665939 NCBI chr 7:143,055,282...143,056,882
Ensembl chr 7:143,055,282...143,056,887
JBrowse link
G Phlda3 pleckstrin homology like domain, family A, member 3 affects expression ISO Orphenadrine affects the expression of PHLDA3 mRNA CTD PMID:23665939 NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874
JBrowse link
G Phldb3 pleckstrin homology like domain, family B, member 3 affects expression ISO Orphenadrine affects the expression of PHLDB3 mRNA CTD PMID:23665939 NCBI chr 7:24,309,731...24,328,722
Ensembl chr 7:24,310,188...24,328,722
JBrowse link
G Phospho1 phosphatase, orphan 1 affects expression ISO Orphenadrine affects the expression of PHOSPHO1 mRNA CTD PMID:23665939 NCBI chr11:95,715,326...95,722,966
Ensembl chr11:95,715,325...95,722,966
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma affects expression ISO Orphenadrine affects the expression of PIP5K1C mRNA CTD PMID:23665939 NCBI chr10:81,128,669...81,155,808
Ensembl chr10:81,128,797...81,155,807
JBrowse link
G Plekhf2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 affects expression ISO Orphenadrine affects the expression of PLEKHF2 mRNA CTD PMID:23665939 NCBI chr 4:10,988,662...11,007,619
Ensembl chr 4:10,988,662...11,007,927
JBrowse link
G Plekhh1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 affects expression ISO Orphenadrine affects the expression of PLEKHH1 mRNA CTD PMID:23665939 NCBI chr12:79,075,937...79,128,429
Ensembl chr12:79,075,937...79,128,429
JBrowse link
G Plin3 perilipin 3 affects expression ISO Orphenadrine affects the expression of PLIN3 mRNA CTD PMID:23665939 NCBI chr17:56,585,962...56,597,511
Ensembl chr17:56,584,476...56,599,873
JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 affects expression ISO Orphenadrine affects the expression of PMEPA1 mRNA CTD PMID:23665939 NCBI chr 2:173,066,251...173,118,329
Ensembl chr 2:173,066,251...173,118,326
JBrowse link
G Pmp22 peripheral myelin protein 22 affects expression ISO Orphenadrine affects the expression of PMP22 mRNA CTD PMID:23665939 NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
JBrowse link
G Polg2 polymerase (DNA directed), gamma 2, accessory subunit affects expression ISO Orphenadrine affects the expression of POLG2 mRNA CTD PMID:23665939 NCBI chr11:106,659,030...106,670,363
Ensembl chr11:106,659,079...106,670,363
JBrowse link
G Ppm1j protein phosphatase 1J affects expression ISO Orphenadrine affects the expression of PPM1J mRNA CTD PMID:23665939 NCBI chr 3:104,688,322...104,693,334
Ensembl chr 3:104,688,372...104,693,334
JBrowse link
G Ppm1k protein phosphatase 1K (PP2C domain containing) affects expression ISO Orphenadrine affects the expression of PPM1K mRNA CTD PMID:23665939 NCBI chr 6:57,483,487...57,512,537
Ensembl chr 6:57,483,487...57,512,453
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A affects expression ISO Orphenadrine affects the expression of PPP1R1A mRNA CTD PMID:23665939 NCBI chr15:103,438,706...103,446,465
Ensembl chr15:103,438,706...103,446,430
JBrowse link
G Prelid2 PRELI domain containing 2 affects expression ISO Orphenadrine affects the expression of PRELID2 mRNA CTD PMID:23665939 NCBI chr18:42,008,761...42,084,259
Ensembl chr18:42,008,665...42,084,307
JBrowse link
G Prkch protein kinase C, eta affects expression ISO Orphenadrine affects the expression of PRKCH mRNA CTD PMID:23665939 NCBI chr12:73,631,570...73,824,959
Ensembl chr12:73,631,570...73,824,959
JBrowse link
G Prlr prolactin receptor affects expression ISO Orphenadrine affects the expression of PRLR mRNA CTD PMID:23665939 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
JBrowse link
G Prp2 proline rich protein 2 affects expression ISO Orphenadrine affects the expression of PRP2 mRNA CTD PMID:23665939 NCBI chr 6:132,572,874...132,577,665
Ensembl chr 6:132,572,876...132,578,199
JBrowse link
G Prrg4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) affects expression ISO Orphenadrine affects the expression of PRRG4 mRNA CTD PMID:23665939 NCBI chr 2:104,657,374...104,680,216
Ensembl chr 2:104,661,086...104,680,221
JBrowse link
G Prss53 serine protease 53 affects expression ISO Orphenadrine affects the expression of PRSS53 mRNA CTD PMID:23665939 NCBI chr 7:127,484,616...127,490,594
Ensembl chr 7:127,485,013...127,490,142
JBrowse link
G Ptprn protein tyrosine phosphatase receptor type N affects expression ISO Orphenadrine affects the expression of PTPRN mRNA CTD PMID:23665939 NCBI chr 1:75,223,679...75,241,437
Ensembl chr 1:75,223,671...75,241,146
JBrowse link
G Pvr poliovirus receptor affects expression ISO Orphenadrine affects the expression of PVR mRNA CTD PMID:23665939 NCBI chr 7:19,637,503...19,655,068
Ensembl chr 7:19,637,503...19,655,085
JBrowse link
G Pwwp2b PWWP domain containing 2B affects expression ISO Orphenadrine affects the expression of PWWP2B mRNA CTD PMID:23665939 NCBI chr 7:138,828,398...138,847,172
Ensembl chr 7:138,828,398...138,849,819
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 (class I) affects expression ISO Orphenadrine affects the expression of RAB11FIP5 mRNA CTD PMID:23665939 NCBI chr 6:85,311,944...85,351,663
Ensembl chr 6:85,311,944...85,351,616
JBrowse link
G Rab23 RAB23, member RAS oncogene family affects expression ISO Orphenadrine affects the expression of RAB23 mRNA CTD PMID:23665939 NCBI chr 1:33,758,991...33,781,642
Ensembl chr 1:33,758,968...33,781,645
JBrowse link
G Rab3d RAB3D, member RAS oncogene family affects expression ISO Orphenadrine affects the expression of RAB3D mRNA CTD PMID:23665939 NCBI chr 9:21,818,787...21,829,623
Ensembl chr 9:21,818,787...21,829,488
JBrowse link
G Rarg retinoic acid receptor, gamma affects expression ISO Orphenadrine affects the expression of RARG mRNA CTD PMID:23665939 NCBI chr15:102,143,373...102,165,891
Ensembl chr15:102,143,373...102,165,952
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 affects expression ISO Orphenadrine affects the expression of RASSF1 mRNA CTD PMID:23665939 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466
JBrowse link
G Rell1 RELT-like 1 affects expression ISO Orphenadrine affects the expression of RELL1 mRNA CTD PMID:23665939 NCBI chr 5:64,047,296...64,126,165
Ensembl chr 5:64,066,240...64,126,240
JBrowse link
G Renbp renin binding protein affects expression ISO Orphenadrine affects the expression of RENBP mRNA CTD PMID:23665939 NCBI chr  X:72,965,727...72,974,408
Ensembl chr  X:72,965,727...72,974,456
JBrowse link
G Repin1 replication initiator 1 affects expression ISO Orphenadrine affects the expression of REPIN1 mRNA CTD PMID:23665939 NCBI chr 6:48,570,817...48,576,016
Ensembl chr 6:48,570,817...48,576,016
JBrowse link
G Resp18 regulated endocrine-specific protein 18 affects expression ISO Orphenadrine affects the expression of RESP18 mRNA CTD PMID:23665939 NCBI chr 1:75,248,841...75,255,059
Ensembl chr 1:75,248,843...75,255,059
JBrowse link
G Rgs16 regulator of G-protein signaling 16 affects expression ISO Orphenadrine affects the expression of RGS16 mRNA CTD PMID:23665939 NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 affects expression ISO Orphenadrine affects the expression of RHBDF2 mRNA CTD PMID:23665939 NCBI chr11:116,488,991...116,517,786
Ensembl chr11:116,488,991...116,517,845
JBrowse link
G Rhoc ras homolog family member C affects expression ISO Orphenadrine affects the expression of RHOC mRNA CTD PMID:23665939 NCBI chr 3:104,696,350...104,701,775
Ensembl chr 3:104,695,691...104,701,775
JBrowse link
G Rhof ras homolog family member F (in filopodia) affects expression ISO Orphenadrine affects the expression of RHOF mRNA CTD PMID:23665939 NCBI chr 5:123,256,243...123,270,692
Ensembl chr 5:123,241,107...123,270,755
JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 affects expression ISO Orphenadrine affects the expression of RMDN2 mRNA CTD PMID:23665939 NCBI chr17:79,886,025...80,000,630
Ensembl chr17:79,919,292...80,000,621
JBrowse link
G Rnd1 Rho family GTPase 1 affects expression ISO Orphenadrine affects the expression of RND1 mRNA CTD PMID:23665939 NCBI chr15:98,567,086...98,575,342
Ensembl chr15:98,561,302...98,575,342
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression ISO Orphenadrine affects the expression of SBSPON mRNA CTD PMID:23665939 NCBI chr 1:15,924,086...15,962,946
Ensembl chr 1:15,924,086...15,962,946
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 affects expression ISO Orphenadrine affects the expression of SCD1 mRNA CTD PMID:23665939 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Scnn1a sodium channel, nonvoltage-gated 1 alpha affects expression ISO Orphenadrine affects the expression of SCNN1A mRNA CTD PMID:23665939 NCBI chr 6:125,286,657...125,321,906
Ensembl chr 6:125,297,622...125,321,906
JBrowse link
G Sdc3 syndecan 3 affects expression ISO Orphenadrine affects the expression of SDC3 mRNA CTD PMID:23665939 NCBI chr 4:130,519,855...130,553,629
Ensembl chr 4:130,519,848...130,553,630
JBrowse link
G Sebox SEBOX homeobox affects expression ISO Orphenadrine affects the expression of SEBOX mRNA CTD PMID:23665939 NCBI chr11:78,394,328...78,395,907
Ensembl chr11:78,394,273...78,395,907
JBrowse link
G Serinc2 serine incorporator 2 affects expression ISO Orphenadrine affects the expression of SERINC2 mRNA CTD PMID:23665939 NCBI chr 4:130,147,289...130,172,993
Ensembl chr 4:130,147,288...130,172,998
JBrowse link
G Serpina7 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 affects expression ISO Orphenadrine affects the expression of SERPINA7 mRNA CTD PMID:23665939 NCBI chr  X:137,979,998...137,985,985
Ensembl chr  X:137,980,006...137,985,985
JBrowse link
G Sertad1 SERTA domain containing 1 affects expression ISO Orphenadrine affects the expression of SERTAD1 mRNA CTD PMID:23665939 NCBI chr 7:27,186,378...27,189,741
Ensembl chr 7:27,186,335...27,189,741
JBrowse link
G Setd7 SET domain containing (lysine methyltransferase) 7 affects expression ISO Orphenadrine affects the expression of SETD7 mRNA CTD PMID:23665939 NCBI chr 3:51,422,740...51,468,519
Ensembl chr 3:51,422,740...51,468,300
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 affects expression ISO Orphenadrine affects the expression of SGK1 mRNA CTD PMID:23665939 NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B affects expression ISO Orphenadrine affects the expression of SH3PXD2B mRNA CTD PMID:23665939 NCBI chr11:32,297,777...32,378,189
Ensembl chr11:32,297,820...32,378,173
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 affects expression ISO Orphenadrine affects the expression of SHANK3 mRNA CTD PMID:23665939 NCBI chr15:89,376,929...89,444,464
Ensembl chr15:89,383,826...89,444,464
JBrowse link
G Shisa4 shisa family member 4 affects expression ISO Orphenadrine affects the expression of SHISA4 mRNA CTD PMID:23665939 NCBI chr 1:135,298,578...135,302,812
Ensembl chr 1:135,298,795...135,302,975
JBrowse link
G Shroom3 shroom family member 3 affects expression ISO Orphenadrine affects the expression of SHROOM3 mRNA CTD PMID:23665939 NCBI chr 5:92,831,294...93,113,618
Ensembl chr 5:92,831,294...93,113,177
JBrowse link
G Sidt1 SID1 transmembrane family, member 1 affects expression ISO Orphenadrine affects the expression of SIDT1 mRNA CTD PMID:23665939 NCBI chr16:44,060,540...44,153,575
Ensembl chr16:44,060,543...44,153,559
JBrowse link
G Sinhcaf SIN3-HDAC complex associated factor affects expression ISO Orphenadrine affects the expression of SINHCAF mRNA CTD PMID:23665939 NCBI chr 6:148,822,538...148,847,968
Ensembl chr 6:148,822,533...148,847,965
JBrowse link
G Sipa1 signal-induced proliferation associated gene 1 affects expression ISO Orphenadrine affects the expression of SIPA1 mRNA CTD PMID:23665939 NCBI chr19:5,701,211...5,713,758
Ensembl chr19:5,701,213...5,713,735
JBrowse link
G Skil SKI-like affects expression ISO Orphenadrine affects the expression of SKIL mRNA CTD PMID:23665939 NCBI chr 3:31,149,259...31,176,741
Ensembl chr 3:31,149,207...31,176,726
JBrowse link
G Slc12a4 solute carrier family 12, member 4 affects expression ISO Orphenadrine affects the expression of SLC12A4 mRNA CTD PMID:23665939 NCBI chr 8:106,670,222...106,692,781
Ensembl chr 8:106,670,222...106,692,729
JBrowse link
G Slc16a10 solute carrier family 16 (monocarboxylic acid transporters), member 10 affects expression ISO Orphenadrine affects the expression of SLC16A10 mRNA CTD PMID:23665939 NCBI chr10:39,909,528...40,018,262
Ensembl chr10:39,909,528...40,018,254
JBrowse link
G Slc16a11 solute carrier family 16 (monocarboxylic acid transporters), member 11 affects expression ISO Orphenadrine affects the expression of SLC16A11 mRNA CTD PMID:23665939 NCBI chr11:70,104,717...70,107,239
Ensembl chr11:70,103,578...70,107,243
JBrowse link
G Slc16a14 solute carrier family 16 (monocarboxylic acid transporters), member 14 affects expression ISO Orphenadrine affects the expression of SLC16A14 mRNA CTD PMID:23665939 NCBI chr 1:84,881,344...84,912,927
Ensembl chr 1:84,883,619...84,912,855
JBrowse link
G Slc16a5 solute carrier family 16 (monocarboxylic acid transporters), member 5 affects expression ISO Orphenadrine affects the expression of SLC16A5 mRNA CTD PMID:23665939 NCBI chr11:115,353,231...115,365,224
Ensembl chr11:115,353,300...115,365,224
JBrowse link
G Slc16a6 solute carrier family 16 (monocarboxylic acid transporters), member 6 affects expression ISO Orphenadrine affects the expression of SLC16A6 mRNA CTD PMID:23665939 NCBI chr11:109,341,681...109,366,428
Ensembl chr11:109,341,681...109,364,424
JBrowse link
G Slc1a4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 affects expression ISO Orphenadrine affects the expression of SLC1A4 mRNA CTD PMID:23665939 NCBI chr11:20,252,180...20,282,713
Ensembl chr11:20,252,180...20,282,713
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Orphenadrine inhibits the reaction [SLC22A2 protein polymorphism results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Orphenadrine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc30a2 solute carrier family 30 (zinc transporter), member 2 affects expression ISO Orphenadrine affects the expression of SLC30A2 mRNA CTD PMID:23665939 NCBI chr 4:134,070,357...134,081,795
Ensembl chr 4:134,070,492...134,081,795
JBrowse link
G Slc35f2 solute carrier family 35, member F2 affects expression ISO Orphenadrine affects the expression of SLC35F2 mRNA CTD PMID:23665939 NCBI chr 9:53,678,733...53,725,445
Ensembl chr 9:53,678,822...53,725,438
JBrowse link
G Slc41a1 solute carrier family 41, member 1 affects expression ISO Orphenadrine affects the expression of SLC41A1 mRNA CTD PMID:23665939 NCBI chr 1:131,755,236...131,776,601
Ensembl chr 1:131,755,231...131,776,603
JBrowse link
G Slc6a8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 affects expression ISO Orphenadrine affects the expression of SLC6A8 mRNA CTD PMID:23665939 NCBI chr  X:72,716,739...72,726,108
Ensembl chr  X:72,716,756...72,726,108
JBrowse link
G Slc7a4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 affects expression ISO Orphenadrine affects the expression of SLC7A4 mRNA CTD PMID:23665939 NCBI chr16:17,389,882...17,394,619
Ensembl chr16:17,389,882...17,401,078
JBrowse link
G Slc9a7 solute carrier family 9 (sodium/hydrogen exchanger), member 7 affects expression ISO Orphenadrine affects the expression of SLC9A7 mRNA CTD PMID:23665939 NCBI chr  X:19,965,090...20,158,274
Ensembl chr  X:19,971,993...20,158,046
JBrowse link
G Smad6 SMAD family member 6 affects expression ISO Orphenadrine affects the expression of SMAD6 mRNA CTD PMID:23665939 NCBI chr 9:63,860,358...63,929,374
Ensembl chr 9:63,860,358...63,929,341
JBrowse link
G Smtnl2 smoothelin-like 2 affects expression ISO Orphenadrine affects the expression of SMTNL2 mRNA CTD PMID:23665939 NCBI chr11:72,279,989...72,302,539
Ensembl chr11:72,279,990...72,302,539
JBrowse link
G Snx10 sorting nexin 10 affects expression ISO Orphenadrine affects the expression of SNX10 mRNA CTD PMID:23665939 NCBI chr 6:51,500,882...51,567,659
Ensembl chr 6:51,500,881...51,567,659
JBrowse link
G Sort1 sortilin 1 affects expression ISO Orphenadrine affects the expression of SORT1 mRNA CTD PMID:23665939 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
JBrowse link
G Sox18 SRY (sex determining region Y)-box 18 affects expression ISO Orphenadrine affects the expression of SOX18 mRNA CTD PMID:23665939 NCBI chr 2:181,311,630...181,313,433
Ensembl chr 2:181,311,629...181,313,433
JBrowse link
G Sox4 SRY (sex determining region Y)-box 4 affects expression ISO Orphenadrine affects the expression of SOX4 mRNA CTD PMID:23665939 NCBI chr13:29,132,902...29,137,682
Ensembl chr13:29,132,902...29,137,696
JBrowse link
G Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) affects expression ISO Orphenadrine affects the expression of SPC25 mRNA CTD PMID:23665939 NCBI chr 2:69,009,753...69,036,583
Ensembl chr 2:69,024,239...69,036,538
JBrowse link
G Spink12 serine peptidase inhibitor, Kazal type 12 affects expression ISO Orphenadrine affects the expression of SPINK9 mRNA CTD PMID:23665939 NCBI chr18:44,237,357...44,241,610
Ensembl chr18:44,237,474...44,241,610
JBrowse link
G Spock2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 affects expression ISO Orphenadrine affects the expression of SPOCK2 mRNA CTD PMID:23665939 NCBI chr10:59,942,079...59,971,020
Ensembl chr10:59,942,041...59,971,020
JBrowse link
G Srcin1 SRC kinase signaling inhibitor 1 affects expression ISO Orphenadrine affects the expression of SRCIN1 mRNA CTD PMID:23665939 NCBI chr11:97,400,166...97,466,059
Ensembl chr11:97,400,166...97,467,012
JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 affects expression ISO Orphenadrine affects the expression of SRD5A1 mRNA CTD PMID:23665939 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 affects expression ISO Orphenadrine affects the expression of STAC3 mRNA CTD PMID:23665939 NCBI chr10:127,337,505...127,344,692
Ensembl chr10:127,337,555...127,344,692
JBrowse link
G Stard9 StAR related lipid transfer domain containing 9 affects expression ISO Orphenadrine affects the expression of STARD9 mRNA CTD PMID:23665939 NCBI chr 2:120,459,567...120,562,371
Ensembl chr 2:120,459,602...120,562,376
JBrowse link
G Stxbp1 syntaxin binding protein 1 affects expression ISO Orphenadrine affects the expression of STXBP1 mRNA CTD PMID:23665939 NCBI chr 2:32,677,619...32,737,249
Ensembl chr 2:32,677,614...32,737,257
JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 affects expression ISO Orphenadrine affects the expression of SULT1E1 mRNA CTD PMID:23665939 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
JBrowse link
G Syde1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) affects expression ISO Orphenadrine affects the expression of SYDE1 mRNA CTD PMID:23665939 NCBI chr10:78,420,336...78,427,798
Ensembl chr10:78,420,337...78,427,798
JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) affects expression ISO Orphenadrine affects the expression of SYNGAP1 mRNA CTD PMID:23665939 NCBI chr17:27,160,186...27,191,408
Ensembl chr17:27,160,227...27,191,408
JBrowse link
G Synj2 synaptojanin 2 affects expression ISO Orphenadrine affects the expression of SYNJ2 mRNA CTD PMID:23665939 NCBI chr17:5,991,555...6,106,041
Ensembl chr17:5,991,555...6,094,565
JBrowse link
G Synm synemin, intermediate filament protein affects expression ISO Orphenadrine affects the expression of SYNM mRNA CTD PMID:23665939 NCBI chr 7:67,379,909...67,409,490
Ensembl chr 7:67,379,908...67,409,490
JBrowse link
G Tbcel tubulin folding cofactor E-like affects expression ISO Orphenadrine affects the expression of TBCEL mRNA CTD PMID:23665939 NCBI chr 9:42,323,612...42,383,534
Ensembl chr 9:42,323,612...42,419,105
JBrowse link
G Tead2 TEA domain family member 2 affects expression ISO Orphenadrine affects the expression of TEAD2 mRNA CTD PMID:23665939 NCBI chr 7:44,865,216...44,882,892
Ensembl chr 7:44,865,177...44,883,068
JBrowse link
G Tenm2 teneurin transmembrane protein 2 affects expression ISO Orphenadrine affects the expression of TENM2 mRNA CTD PMID:23665939 NCBI chr11:35,897,483...37,881,486
Ensembl chr11:35,897,483...37,126,791
JBrowse link
G Tex13b testis expressed 13B affects expression ISO Orphenadrine affects the expression of TEX13B mRNA CTD PMID:23665939 NCBI chr  X:139,709,056...139,714,182
Ensembl chr  X:139,709,056...139,714,182
JBrowse link
G Tex36 testis expressed 36 affects expression ISO Orphenadrine affects the expression of TEX36 mRNA CTD PMID:23665939 NCBI chr 7:133,188,753...133,203,844
Ensembl chr 7:133,188,753...133,203,887
JBrowse link
G Them6 thioesterase superfamily member 6 affects expression ISO Orphenadrine affects the expression of THEM6 mRNA CTD PMID:23665939 NCBI chr15:74,593,083...74,596,222
Ensembl chr15:74,593,053...74,596,488
JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain affects expression ISO Orphenadrine affects the expression of TIFA mRNA CTD PMID:23665939 NCBI chr 3:127,582,524...127,592,043
Ensembl chr 3:127,583,454...127,625,813
JBrowse link
G Tlcd4 TLC domain containing 4 affects expression ISO Orphenadrine affects the expression of TLCD4 mRNA CTD PMID:23665939 NCBI chr 3:120,995,657...121,076,756
Ensembl chr 3:120,995,410...121,076,747
JBrowse link
G Tlnrd1 talin rod domain containing 1 affects expression ISO Orphenadrine affects the expression of TLNRD1 mRNA CTD PMID:23665939 NCBI chr 7:83,529,703...83,533,549
Ensembl chr 7:83,529,081...83,533,513
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression ISO Orphenadrine affects the expression of TMBIM1 mRNA CTD PMID:23665939 NCBI chr 1:74,327,406...74,343,495
Ensembl chr 1:74,327,406...74,344,781
JBrowse link
G Tmem184b transmembrane protein 184b affects expression ISO Orphenadrine affects the expression of TMEM184B mRNA CTD PMID:23665939 NCBI chr15:79,244,884...79,287,503
Ensembl chr15:79,244,884...79,287,769
JBrowse link
G Tmem184c transmembrane protein 184C affects expression ISO Orphenadrine affects the expression of TMEM184C mRNA CTD PMID:23665939 NCBI chr 8:78,322,607...78,337,343
Ensembl chr 8:78,322,611...78,337,327
JBrowse link
G Tmem200b transmembrane protein 200B affects expression ISO Orphenadrine affects the expression of TMEM200B mRNA CTD PMID:23665939 NCBI chr 4:131,648,515...131,651,267
Ensembl chr 4:131,648,511...131,650,451
JBrowse link
G Tnfaip2 tumor necrosis factor, alpha-induced protein 2 affects expression ISO Orphenadrine affects the expression of TNFAIP2 mRNA CTD PMID:23665939 NCBI chr12:111,408,898...111,421,452
Ensembl chr12:111,408,903...111,421,452
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) affects expression ISO Orphenadrine affects the expression of TNFRSF11B mRNA CTD PMID:23665939 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a affects expression ISO Orphenadrine affects the expression of TNFRSF12A mRNA CTD PMID:23665939 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tnk1 tyrosine kinase, non-receptor, 1 affects expression ISO Orphenadrine affects the expression of TNK1 mRNA CTD PMID:23665939 NCBI chr11:69,741,389...69,749,556
Ensembl chr11:69,741,831...69,749,556
JBrowse link
G Tns1 tensin 1 affects expression ISO Orphenadrine affects the expression of TNS1 mRNA CTD PMID:23665939 NCBI chr 1:73,949,391...74,163,707
Ensembl chr 1:73,949,390...74,163,608
JBrowse link
G Togaram2 TOG array regulator of axonemal microtubules 2 affects expression ISO Orphenadrine affects the expression of TOGARAM2 mRNA CTD PMID:23665939 NCBI chr17:71,980,153...72,036,666
Ensembl chr17:71,980,256...72,036,664
JBrowse link
G Tox3 TOX high mobility group box family member 3 affects expression ISO Orphenadrine affects the expression of TOX3 mRNA CTD PMID:23665939 NCBI chr 8:90,973,665...91,075,746
Ensembl chr 8:90,973,668...91,074,971
JBrowse link
G Tpm1 tropomyosin 1, alpha affects expression ISO Orphenadrine affects the expression of TPM1 mRNA CTD PMID:23665939 NCBI chr 9:66,929,872...66,956,954
Ensembl chr 9:66,929,872...66,956,688
JBrowse link
G Traf4 TNF receptor associated factor 4 affects expression ISO Orphenadrine affects the expression of TRAF4 mRNA CTD PMID:23665939 NCBI chr11:78,049,249...78,056,405
Ensembl chr11:78,049,325...78,056,415
JBrowse link
G Trim36 tripartite motif-containing 36 affects expression ISO Orphenadrine affects the expression of TRIM36 mRNA CTD PMID:23665939 NCBI chr18:46,298,367...46,345,674
Ensembl chr18:46,298,367...46,345,674
JBrowse link
G Trim54 tripartite motif-containing 54 affects expression ISO Orphenadrine affects the expression of TRIM54 mRNA CTD PMID:23665939 NCBI chr 5:31,273,956...31,294,970
Ensembl chr 5:31,274,056...31,294,974
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 affects expression ISO Orphenadrine affects the expression of TRPM2 mRNA CTD PMID:23665939 NCBI chr10:77,743,556...77,805,746
Ensembl chr10:77,743,556...77,806,397
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 affects expression ISO Orphenadrine affects the expression of TRPV2 mRNA CTD PMID:23665939 NCBI chr11:62,465,312...62,491,131
Ensembl chr11:62,465,312...62,491,341
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 affects expression ISO Orphenadrine affects the expression of TSC22D3 mRNA CTD PMID:23665939 NCBI chr  X:139,440,277...139,501,257
Ensembl chr  X:139,440,277...139,501,408
JBrowse link
G Ttpal tocopherol (alpha) transfer protein-like affects expression ISO Orphenadrine affects the expression of TTPAL mRNA CTD PMID:23665939 NCBI chr 2:163,444,206...163,460,933
Ensembl chr 2:163,444,234...163,460,933
JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 affects expression ISO Orphenadrine affects the expression of UBA7 mRNA CTD PMID:23665939 NCBI chr 9:107,852,766...107,861,255
Ensembl chr 9:107,852,704...107,861,259
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 affects expression ISO Orphenadrine affects the expression of UGT2A3 mRNA CTD PMID:23665939 NCBI chr 5:87,472,694...87,485,054
Ensembl chr 5:87,472,831...87,485,054
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 affects expression ISO Orphenadrine affects the expression of UGT2B1 mRNA CTD PMID:23665939 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389
JBrowse link
G Unc5b unc-5 netrin receptor B affects expression ISO Orphenadrine affects the expression of UNC5B mRNA CTD PMID:23665939 NCBI chr10:60,598,373...60,667,360
Ensembl chr10:60,598,372...60,667,360
JBrowse link
G Unkl unkempt family like zinc finger affects expression ISO Orphenadrine affects the expression of UNKL mRNA CTD PMID:23665939 NCBI chr17:25,407,336...25,453,417
Ensembl chr17:25,407,371...25,453,417
JBrowse link
G Upp2 uridine phosphorylase 2 affects expression ISO Orphenadrine affects the expression of UPP2 mRNA CTD PMID:23665939 NCBI chr 2:58,456,329...58,685,858
Ensembl chr 2:58,457,310...58,682,983
JBrowse link
G Usp18 ubiquitin specific peptidase 18 affects expression ISO Orphenadrine affects the expression of USP18 mRNA CTD PMID:23665939 NCBI chr 6:121,222,865...121,247,876
Ensembl chr 6:121,222,865...121,247,876
JBrowse link
G Vav2 vav 2 oncogene affects expression ISO Orphenadrine affects the expression of VAV2 mRNA CTD PMID:23665939 NCBI chr 2:27,152,116...27,317,620
Ensembl chr 2:27,152,116...27,317,045
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 affects expression ISO Orphenadrine affects the expression of VIPR1 mRNA CTD PMID:23665939 NCBI chr 9:121,471,782...121,502,020
Ensembl chr 9:121,471,782...121,502,020
JBrowse link
G Vnn1 vanin 1 affects expression ISO Orphenadrine affects the expression of VNN1 mRNA CTD PMID:23665939 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
JBrowse link
G Wfdc1 WAP four-disulfide core domain 1 affects expression ISO Orphenadrine affects the expression of WFDC1 mRNA CTD PMID:23665939 NCBI chr 8:120,393,104...120,414,759
Ensembl chr 8:120,393,104...120,414,961
JBrowse link
G Wipf3 WAS/WASL interacting protein family, member 3 affects expression ISO Orphenadrine affects the expression of WIPF3 mRNA CTD PMID:23665939 NCBI chr 6:54,406,206...54,480,753
Ensembl chr 6:54,406,588...54,480,753
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound affects expression ISO Orphenadrine affects the expression of XPNPEP2 mRNA CTD PMID:23665939 NCBI chr  X:47,195,790...47,225,859
Ensembl chr  X:47,197,602...47,225,858
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 affects expression ISO Orphenadrine affects the expression of ZBTB10 mRNA CTD PMID:23665939 NCBI chr 3:9,315,627...9,350,393
Ensembl chr 3:9,315,662...9,350,393
JBrowse link
G Zbtb42 zinc finger and BTB domain containing 42 affects expression ISO Orphenadrine affects the expression of ZBTB42 mRNA CTD PMID:23665939 NCBI chr12:112,645,042...112,649,181
Ensembl chr12:112,645,262...112,649,181
JBrowse link
G Zc2hc1a zinc finger, C2HC-type containing 1A affects expression ISO Orphenadrine affects the expression of ZC2HC1A mRNA CTD PMID:23665939 NCBI chr 3:7,568,475...7,618,908
Ensembl chr 3:7,568,543...7,618,896
JBrowse link
G Zdhhc8 zinc finger, DHHC domain containing 8 affects expression ISO Orphenadrine affects the expression of ZDHHC8 mRNA CTD PMID:23665939 NCBI chr16:18,038,612...18,056,471
Ensembl chr16:18,038,617...18,053,000
JBrowse link
G Zfp319 zinc finger protein 319 affects expression ISO Orphenadrine affects the expression of ZFP319 mRNA CTD PMID:23665939 NCBI chr 8:96,052,759...96,058,439
Ensembl chr 8:96,049,639...96,058,578
JBrowse link
G Zfp334 zinc finger protein 334 affects expression ISO Orphenadrine affects the expression of ZFP334 mRNA CTD PMID:23665939 NCBI chr 2:165,216,184...165,230,234
Ensembl chr 2:165,216,184...165,230,179
JBrowse link
G Zfp354a zinc finger protein 354A affects expression ISO Orphenadrine affects the expression of ZFP354A mRNA CTD PMID:23665939 NCBI chr11:50,950,052...50,963,626
Ensembl chr11:50,950,084...50,963,626
JBrowse link
G Zfp36 zinc finger protein 36 affects expression ISO Orphenadrine affects the expression of ZFP36 mRNA CTD PMID:23665939 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 affects expression ISO Orphenadrine affects the expression of ZFP36L2 mRNA CTD PMID:23665939 NCBI chr17:84,491,352...84,495,375
Ensembl chr17:84,491,359...84,495,375
JBrowse link
G Zfp503 zinc finger protein 503 affects expression ISO Orphenadrine affects the expression of ZFP503 mRNA CTD PMID:23665939 NCBI chr14:22,034,030...22,039,669
Ensembl chr14:22,034,027...22,039,669
JBrowse link
G Zfp668 zinc finger protein 668 affects expression ISO Orphenadrine affects the expression of ZFP668 mRNA CTD PMID:23665939 NCBI chr 7:127,460,197...127,476,008
Ensembl chr 7:127,462,219...127,476,000
JBrowse link
pergolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein multiple interactions ISO
EXP
Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]
Pergolide inhibits the reaction [Levodopa results in increased expression of BAX protein]
CTD PMID:15081873 PMID:15672541 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions ISO Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein] CTD PMID:15081873 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Drd1 dopamine receptor D1 increases activity ISO Pergolide results in increased activity of DRD1 protein CTD PMID:16129789 NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
JBrowse link
G Drd2 dopamine receptor D2 increases activity ISO Pergolide results in increased activity of DRD2 protein CTD PMID:16129789 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Gdnf glial cell line derived neurotrophic factor increases expression
increases secretion
EXP Pergolide results in increased expression of GDNF mRNA
Pergolide results in increased secretion of GDNF protein
CTD PMID:12770616 NCBI chr15:7,839,529...7,867,061
Ensembl chr15:7,840,327...7,867,056
JBrowse link
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 decreases activity ISO Pergolide results in decreased activity of KCNA5 protein CTD PMID:16129789 NCBI chr 6:126,509,514...126,512,518
Ensembl chr 6:126,509,514...126,512,375
JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 decreases activity ISO Pergolide results in decreased activity of KCNMA1 protein CTD PMID:16129789 NCBI chr14:23,342,356...24,055,173
Ensembl chr14:23,339,499...24,064,559
JBrowse link
G Msh2 mutS homolog 2 multiple interactions ISO Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein] CTD PMID:15081873 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO Pergolide inhibits the reaction [Hydrogen Peroxide affects the localization of NFKB1 protein]; Pergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of NFKB1 protein] CTD PMID:15081873 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Ngf nerve growth factor increases expression
increases secretion
EXP Pergolide results in increased expression of NGF mRNA
Pergolide results in increased secretion of NGF protein
CTD PMID:12770616 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO Pergolide inhibits the reaction [Hydrogen Peroxide affects the localization of RELA protein]; Pergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of RELA protein] CTD PMID:15081873 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Pergolide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO
EXP
Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of BAX protein]; Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein]; Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of MSH2 protein]; Pergolide inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]
Pergolide inhibits the reaction [Levodopa results in increased expression of TRP53 protein]
CTD PMID:15081873 PMID:15672541 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
pimozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO Pimozide results in decreased expression of BCL2 mRNA CTD PMID:12130671 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
ISO istradefylline inhibits the reaction [Pimozide results in increased expression of FOS protein]; Tropicamide promotes the reaction [Pimozide results in increased expression of FOS protein] CTD PMID:19467297 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Kcna10 potassium voltage-gated channel, shaker-related subfamily, member 10 multiple interactions ISO Pimozide inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 3:107,090,459...107,103,037
Ensembl chr 3:107,090,372...107,103,037
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 multiple interactions
decreases activity
ISO Pimozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Pimozide results in decreased activity of KCNH2 protein
CTD PMID:15671647 PMID:19583963 PMID:21158687 PMID:24052561 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Lhb luteinizing hormone beta multiple interactions ISO Pimozide results in decreased secretion of and results in decreased glycosylation of LHB protein CTD PMID:3896764 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Prl prolactin increases expression ISO Pimozide results in increased expression of PRL protein CTD PMID:8915564 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
pramipexole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO Pramipexole inhibits the reaction [amyloid beta-protein (1-42) results in increased activity of ACHE protein] CTD PMID:35868426 NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions ISO Pramipexole inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of ATP5F1A protein] CTD PMID:35868426 NCBI chr18:77,861,468...77,870,569
Ensembl chr18:77,861,429...77,870,569
JBrowse link
G Casp3 caspase 3 multiple interactions ISO pramipexole inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein] CTD PMID:16362428 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO pramipexole binds to and results in increased activity of DRD2 protein CTD PMID:10728880 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO pramipexole binds to and results in increased activity of DRD3 protein CTD PMID:10728880 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16362428 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] CTD PMID:16362428 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Pramipexole results in increased expression of PPARGC1A protein CTD PMID:35868426 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ptprd protein tyrosine phosphatase receptor type D increases expression ISO [Pramipexole cotreated with exercise] increases expression of Ptprd protein in the striatum RGD PMID:37633178 RGD:401976430 NCBI chr 4:75,859,474...78,132,282
Ensembl chr 4:75,859,475...78,130,198
JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) multiple interactions ISO Pramipexole inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of SDHB protein] CTD PMID:35868426 NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
JBrowse link
pridinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO pridinol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO pridinol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
procyclidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases activity ISO Procyclidine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Procyclidine results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO Procyclidine results in increased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Ereg epiregulin increases expression ISO Procyclidine results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Procyclidine results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Procyclidine results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il24 interleukin 24 increases expression ISO Procyclidine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Met met proto-oncogene increases expression ISO Procyclidine results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Procyclidine results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Procyclidine results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Procyclidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Procyclidine results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Procyclidine results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Tnfaip6 tumor necrosis factor alpha induced protein 6 increases expression ISO Procyclidine results in increased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698
JBrowse link
profenamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO
EXP
profenamine results in decreased activity of BCHE protein
profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of acetylthiocholine iodide]; profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; profenamine inhibits the reaction [BCHE protein results in increased hydrolysis of phenyl valerate]
CTD PMID:18656440 PMID:22407886 PMID:28299395 PMID:32278739 PMID:32795450 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO profenamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
ropinirole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO ropinirole results in increased expression of BCL2 protein CTD PMID:18242171 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions ISO ropinirole inhibits the reaction [Rotenone results in increased cleavage of CASP3 protein] CTD PMID:18242171 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 multiple interactions ISO ropinirole inhibits the reaction [Rotenone results in increased cleavage of CASP9 protein] CTD PMID:18242171 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO ropinirole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased activity of CAT protein]] CTD PMID:25053526 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO ropinirole binds to and results in increased activity of DRD2 protein CTD PMID:18393062 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO ropinirole binds to and results in increased activity of DRD3 protein CTD PMID:18242171 PMID:18393062 NCBI chr16:43,574,285...43,646,353
Ensembl chr16:43,574,389...43,643,295
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions ISO ropinirole binds to and results in increased activity of DRD4 protein CTD PMID:18393062 NCBI chr 7:140,871,931...140,874,868
Ensembl chr 7:140,871,919...140,876,377
JBrowse link
G Egr1 early growth response 1 decreases expression ISO ropinirole results in decreased expression of EGR1 mRNA CTD PMID:20452347 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ropinirole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]] CTD PMID:25053526 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO ropinirole inhibits the reaction [Rotenone results in increased phosphorylation of JUN protein] CTD PMID:18242171 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation ISO ropinirole results in increased phosphorylation of MAPK1 protein CTD PMID:18242171 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation ISO ropinirole results in increased phosphorylation of MAPK3 protein CTD PMID:18242171 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO ropinirole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]; ropinirole promotes the reaction [Ceftriaxone inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein]] CTD PMID:25053526 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
tolcapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1110059G10Rik RIKEN cDNA 1110059G10 gene decreases expression ISO tolcapone results in decreased expression of RGD1311745 mRNA CTD PMID:24136188 NCBI chr 9:122,774,154...122,780,065
Ensembl chr 9:122,774,154...122,780,065
JBrowse link
G 2300009A05Rik RIKEN cDNA 2300009A05 gene decreases expression ISO Tolcapone results in decreased expression of C8H15ORF61 mRNA CTD PMID:24136188 NCBI chr 9:63,301,729...63,306,526
Ensembl chr 9:63,301,729...63,306,528
JBrowse link
G Aadac arylacetamide deacetylase decreases expression ISO tolcapone results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
JBrowse link
G Aars1 alanyl-tRNA synthetase 1 increases expression ISO Tolcapone results in increased expression of AARS1 mRNA CTD PMID:24136188 NCBI chr 8:111,759,781...111,784,237
Ensembl chr 8:111,759,776...111,784,296
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases activity ISO tolcapone results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcd2 ATP-binding cassette, sub-family D member 2 affects binding ISO tolcapone binds to ABCD2 protein CTD PMID:19783845 NCBI chr15:91,029,874...91,076,013
Ensembl chr15:91,030,074...91,076,002
JBrowse link
G Abhd10 abhydrolase domain containing 10 affects binding ISO Tolcapone binds to ABHD10 protein CTD PMID:19783845 NCBI chr16:45,550,088...45,563,355
Ensembl chr16:45,550,088...45,563,318
JBrowse link
G Acat2 acetyl-Coenzyme A acetyltransferase 2 increases expression ISO tolcapone results in increased expression of ACAT2 mRNA CTD PMID:24136188 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Acox3 acyl-Coenzyme A oxidase 3, pristanoyl affects binding ISO tolcapone binds to ACOX3 protein CTD PMID:19783845 NCBI chr 5:35,740,293...35,772,397
Ensembl chr 5:35,740,384...35,772,696
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects binding
decreases expression
ISO tolcapone binds to ACSL1 protein
tolcapone results in decreased expression of ACSL1 mRNA; tolcapone results in decreased expression of ACSL1 protein
CTD PMID:19783845 PMID:29688484 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO tolcapone results in decreased expression of ACSL5 protein CTD PMID:29688484 NCBI chr19:55,240,298...55,285,060
Ensembl chr19:55,240,370...55,286,152
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO tolcapone results in increased expression of ACSS2 mRNA CTD PMID:24136188 NCBI chr 2:155,359,963...155,404,663
Ensembl chr 2:155,359,868...155,427,644
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta affects binding ISO tolcapone binds to ACTA2 protein CTD PMID:19783845 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects binding ISO tolcapone binds to ADPRHL1 protein CTD PMID:19783845 NCBI chr 8:13,268,449...13,304,079
Ensembl chr 8:13,271,663...13,304,162
JBrowse link
G Aga aspartylglucosaminidase decreases expression ISO tolcapone results in decreased expression of AGA mRNA CTD PMID:24136188 NCBI chr 8:53,964,718...53,976,457
Ensembl chr 8:53,964,762...53,976,456
JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression ISO tolcapone results in decreased expression of AIF1 mRNA CTD PMID:24136188 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044
JBrowse link
G Ak2 adenylate kinase 2 affects binding ISO tolcapone binds to AK2 protein CTD PMID:19783845 NCBI chr 4:128,887,017...128,905,322
Ensembl chr 4:128,885,751...128,905,322
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 decreases expression ISO tolcapone results in decreased expression of AKR1C3 mRNA CTD PMID:24136188 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Akr1c6 aldo-keto reductase family 1, member C6 affects binding ISO Tolcapone binds to AKR1C1 protein CTD PMID:19783845 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects binding ISO tolcapone binds to AKR1D1 protein CTD PMID:19783845 NCBI chr 6:37,506,913...37,551,856
Ensembl chr 6:37,507,108...37,545,750
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 affects binding ISO tolcapone binds to ALDH18A1 protein CTD PMID:19783845 NCBI chr19:40,538,701...40,576,907
Ensembl chr19:40,538,701...40,576,907
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects binding ISO tolcapone binds to ALDH1B1 protein CTD PMID:19783845 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression ISO tolcapone results in increased expression of ALDH1L1 mRNA CTD PMID:24136188 NCBI chr 6:90,527,751...90,576,153
Ensembl chr 6:90,463,409...90,577,185
JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 affects binding ISO tolcapone binds to ALDH3A2 protein CTD PMID:19783845 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290
JBrowse link
G Alg13 asparagine-linked glycosylation 13 decreases expression ISO Tolcapone results in decreased expression of ALG13 mRNA CTD PMID:24136188 NCBI chr  X:143,100,962...143,157,446
Ensembl chr  X:143,100,800...143,157,446
JBrowse link
G Amfr autocrine motility factor receptor increases expression ISO tolcapone results in increased expression of AMFR mRNA CTD PMID:24136188 NCBI chr 8:94,698,216...94,739,301
Ensembl chr 8:94,698,216...94,739,470
JBrowse link
G Apmap adipocyte plasma membrane associated protein affects binding ISO tolcapone binds to APMAP protein CTD PMID:19783845 NCBI chr 2:150,425,000...150,450,487
Ensembl chr 2:150,425,000...150,450,487
JBrowse link
G Apoa1 apolipoprotein A-I affects binding ISO tolcapone binds to APOA1 protein CTD PMID:19783845 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apob apolipoprotein B decreases expression
decreases secretion
ISO tolcapone results in decreased expression of APOB mRNA
tolcapone results in decreased secretion of APOB protein alternative form
CTD PMID:29688484 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
JBrowse link
G Apoc2 apolipoprotein C2 decreases expression ISO tolcapone results in decreased expression of APOC2 mRNA CTD PMID:24136188 NCBI chr 7:19,405,504...19,411,866
Ensembl chr 7:19,405,504...19,411,866
JBrowse link
G Apoe apolipoprotein E affects binding ISO tolcapone binds to APOE protein CTD PMID:19783845 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Apool apolipoprotein O-like decreases expression ISO tolcapone results in decreased expression of APOOL mRNA CTD PMID:24136188 NCBI chr  X:111,221,049...111,282,452
Ensembl chr  X:111,221,031...111,282,452
JBrowse link
G Arf4 ADP-ribosylation factor 4 affects binding ISO tolcapone binds to ARF4 protein CTD PMID:19783845 NCBI chr14:26,359,289...26,377,997
Ensembl chr14:26,359,229...26,386,239
JBrowse link
G Arl1 ADP-ribosylation factor-like 1 affects binding ISO tolcapone binds to ARL1 protein CTD PMID:19783845 NCBI chr10:88,566,720...88,579,956
Ensembl chr10:88,566,720...88,579,956
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 affects binding ISO tolcapone binds to ATAD1 protein CTD PMID:19783845 NCBI chr19:32,649,958...32,717,187
Ensembl chr19:32,649,038...32,717,186
JBrowse link
G Atad3a ATPase family, AAA domain containing 3A affects binding ISO tolcapone binds to ATAD3A protein CTD PMID:19783845 NCBI chr 4:155,825,097...155,845,579
Ensembl chr 4:155,825,098...155,845,550
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO tolcapone results in increased expression of ATF5 mRNA CTD PMID:24136188 NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082
JBrowse link
G Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide affects binding ISO tolcapone binds to ATP1B3 protein CTD PMID:19783845 NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta affects binding ISO tolcapone binds to ATP5F1B protein CTD PMID:19783845 NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma affects binding ISO Tolcapone binds to ATP5F1C protein CTD PMID:19783845 NCBI chr 2:10,060,841...10,085,321
Ensembl chr 2:10,060,827...10,085,321
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression ISO tolcapone results in decreased expression of ATP5F1E mRNA CTD PMID:24136188 NCBI chr 2:174,302,868...174,305,894
Ensembl chr 2:174,302,865...174,305,898
JBrowse link
G Atp5me ATP synthase membrane subunit e affects binding
decreases expression
ISO tolcapone binds to ATP5ME protein
tolcapone results in decreased expression of ATP5ME mRNA
CTD PMID:19783845 PMID:24136188 NCBI chr 5:108,581,112...108,582,265
Ensembl chr 5:108,581,110...108,582,314
JBrowse link
G Atp5mf ATP synthase membrane subunit f affects binding ISO tolcapone binds to ATP5MF protein CTD PMID:19783845 NCBI chr 5:145,120,514...145,128,351
Ensembl chr 5:145,120,508...145,128,872
JBrowse link
G Atp5mg ATP synthase membrane subunit g decreases expression
affects binding
ISO tolcapone results in decreased expression of ATP5MG mRNA
tolcapone binds to ATP5MG protein
CTD PMID:19783845 PMID:24136188 NCBI chr 9:44,824,546...44,832,470
Ensembl chr 9:44,823,855...44,832,040
JBrowse link
G Atp5mk ATP synthase membrane subunit k decreases expression ISO Tolcapone results in decreased expression of ATP5MK mRNA CTD PMID:24136188 NCBI chr19:47,071,910...47,079,086
Ensembl chr19:47,071,903...47,079,086
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 decreases expression ISO tolcapone results in decreased expression of ATP5PF mRNA CTD PMID:24136188 NCBI chr16:84,624,754...84,632,495
Ensembl chr16:84,624,754...84,632,513
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP affects binding ISO tolcapone binds to ATP5PO protein CTD PMID:19783845 NCBI chr16:91,722,111...91,728,518
Ensembl chr16:91,722,102...91,728,575
Ensembl chr16:91,722,102...91,728,575
JBrowse link
G Auh AU RNA binding protein/enoyl-coenzyme A hydratase affects binding ISO tolcapone binds to AUH protein CTD PMID:19783845 NCBI chr13:52,989,155...53,083,742
Ensembl chr13:52,989,155...53,083,717
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression ISO tolcapone results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 2:110,094,401...110,145,158
Ensembl chr 2:110,093,042...110,144,905
JBrowse link
G Bcam basal cell adhesion molecule affects binding ISO tolcapone binds to BCAM protein CTD PMID:19783845 NCBI chr 7:19,490,063...19,504,457
Ensembl chr 7:19,490,056...19,504,941
JBrowse link
G Bcap29 B cell receptor associated protein 29 decreases expression ISO tolcapone results in decreased expression of BCAP29 mRNA CTD PMID:24136188 NCBI chr12:31,645,353...31,684,657
Ensembl chr12:31,640,966...31,684,657
JBrowse link
G Bcas2 BCAS2 pre-mRNA processing factor decreases expression ISO tolcapone results in decreased expression of BCAS2 mRNA CTD PMID:24136188 NCBI chr 3:103,078,971...103,086,479
Ensembl chr 3:103,078,971...103,086,482
JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 increases expression ISO Tolcapone results in increased expression of BLTP1 mRNA CTD PMID:24136188 NCBI chr 3:36,917,212...37,107,182
Ensembl chr 3:36,917,253...37,107,182
JBrowse link
G Bmper BMP-binding endothelial regulator affects binding ISO tolcapone binds to BMPER protein CTD PMID:19783845 NCBI chr 9:23,134,372...23,396,511
Ensembl chr 9:23,134,372...23,396,496
JBrowse link
G Bms1 BMS1, ribosome biogenesis factor affects binding ISO tolcapone binds to BMS1 protein CTD PMID:19783845 NCBI chr 6:118,360,342...118,396,772
Ensembl chr 6:118,360,342...118,396,435
JBrowse link
G Bpgm 2,3-bisphosphoglycerate mutase decreases expression ISO tolcapone results in decreased expression of BPGM mRNA CTD PMID:24136188 NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548
JBrowse link
G Btf3l4 basic transcription factor 3-like 4 decreases expression ISO tolcapone results in decreased expression of BTF3L4 mRNA CTD PMID:24136188 NCBI chr 4:108,671,489...108,691,445
Ensembl chr 4:108,671,492...108,690,811
JBrowse link
G C1d C1D nuclear receptor co-repressor decreases expression ISO tolcapone results in decreased expression of C1D mRNA CTD PMID:24136188 NCBI chr11:17,207,547...17,219,176
Ensembl chr11:17,207,579...17,219,176
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 decreases expression ISO tolcapone results in decreased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:37,719,660...37,724,020
Ensembl chr  X:37,719,662...37,723,964
JBrowse link
G C4b complement C4B (Chido blood group) increases expression ISO tolcapone results in increased expression of C4B mRNA CTD PMID:24136188 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
JBrowse link
G C8a complement component 8, alpha polypeptide increases expression ISO tolcapone results in increased expression of C8A mRNA CTD PMID:24136188 NCBI chr 4:104,672,876...104,733,684
Ensembl chr 4:104,672,876...104,733,595
JBrowse link
G Cbr4 carbonyl reductase 4 decreases expression ISO tolcapone results in decreased expression of CBR4 mRNA CTD PMID:24136188 NCBI chr 8:61,940,768...61,956,534
Ensembl chr 8:61,940,768...61,959,728
JBrowse link
G Ccnl2 cyclin L2 increases expression ISO tolcapone results in increased expression of CCNL2 mRNA CTD PMID:24136188 NCBI chr 4:155,894,468...155,909,005
Ensembl chr 4:155,896,946...155,909,000
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 affects binding ISO tolcapone binds to CCT7 protein CTD PMID:19783845 NCBI chr 6:85,428,487...85,445,459
Ensembl chr 6:85,428,496...85,445,457
JBrowse link
G Cd36 CD36 molecule increases expression ISO tolcapone results in increased expression of CD36 mRNA CTD PMID:29688484 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cfb complement factor B increases expression ISO tolcapone results in increased expression of CFB mRNA CTD PMID:24136188 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 decreases expression ISO tolcapone results in decreased expression of CHCHD1 mRNA CTD PMID:24136188 NCBI chr14:20,753,095...20,754,493
Ensembl chr14:20,753,074...20,754,493
JBrowse link
G Chchd7 coiled-coil-helix-coiled-coil-helix domain containing 7 decreases expression ISO tolcapone results in decreased expression of CHCHD7 mRNA CTD PMID:24136188 NCBI chr 4:3,938,847...3,951,382
Ensembl chr 4:3,938,888...3,951,046
JBrowse link
G Chrac1 chromatin accessibility complex 1 decreases expression ISO tolcapone results in decreased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr15:72,962,261...72,965,924
Ensembl chr15:72,962,241...72,969,403
JBrowse link
G Churc1 churchill domain containing 1 decreases expression ISO tolcapone results in decreased expression of CHURC1 mRNA CTD PMID:24136188 NCBI chr12:76,812,312...76,829,954
Ensembl chr12:76,812,312...76,829,954
JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A decreases expression ISO tolcapone results in decreased expression of CIAO2A mRNA CTD PMID:24136188 NCBI chr 9:66,033,878...66,046,250
Ensembl chr 9:66,033,893...66,046,237
JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A increases expression ISO tolcapone results in increased expression of CIDEA mRNA CTD PMID:29688484 NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects binding ISO tolcapone binds to CISD1 protein CTD PMID:19783845 NCBI chr10:71,166,324...71,180,679
Ensembl chr10:71,166,310...71,180,784
JBrowse link
G Clec4a3 C-type lectin domain family 4, member a3 decreases expression ISO Tolcapone results in decreased expression of CLEC4A3 mRNA CTD PMID:24136188 NCBI chr 6:122,929,474...122,946,837
Ensembl chr 6:122,929,474...122,946,834
JBrowse link
G Cltc clathrin heavy chain affects binding ISO tolcapone binds to CLTC protein CTD PMID:19783845 NCBI chr11:86,585,178...86,648,637
Ensembl chr11:86,585,177...86,648,391
JBrowse link
G Cnih4 cornichon family AMPA receptor auxiliary protein 4 decreases expression ISO tolcapone results in decreased expression of CNIH4 mRNA CTD PMID:24136188 NCBI chr 1:180,977,437...180,996,559
Ensembl chr 1:180,972,258...180,996,559
JBrowse link
G Commd6 COMM domain containing 6 decreases expression ISO tolcapone results in decreased expression of COMMD6 mRNA CTD PMID:24136188 NCBI chr14:101,871,202...101,877,907
Ensembl chr14:101,870,417...101,878,122
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
increases methylation
affects binding
EXP
ISO
tolcapone results in decreased activity of COMT protein
[tolcapone results in decreased activity of COMT protein] inhibits the reaction [Levodopa results in increased abundance of Homocysteine]; [tolcapone results in decreased activity of COMT protein] inhibits the reaction [Levodopa results in increased abundance of S-Adenosylmethionine]; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Homovanillic Acid; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of 3,4-Dihydroxyphenylacetic Acid; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Dopamine; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Epinephrine; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Levodopa; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Norepinephrine; tolcapone inhibits the reaction [COMT protein results in increased methylation of Levodopa]
[tolcapone results in decreased activity of COMT protein] promotes the reaction [Clozapine results in increased abundance of Dopamine]; [tolcapone results in decreased activity of COMT protein] which results in decreased abundance of Homovanillic Acid; [tolcapone results in decreased activity of COMT protein] which results in increased abundance of 3,4-Dihydroxyphenylacetic Acid; tolcapone inhibits the reaction [[COMT protein results in increased methylation of Epinephrine] which results in increased abundance of Metanephrine]
COMT protein results in increased methylation of tolcapone
tolcapone binds to COMT protein
CTD PMID:2089102 PMID:7566641 PMID:7768073 PMID:8821542 PMID:9333106 More... NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Copg1 coatomer protein complex, subunit gamma 1 affects binding ISO tolcapone binds to COPG1 protein CTD PMID:19783845 NCBI chr 6:87,864,801...87,890,577
Ensembl chr 6:87,864,796...87,890,577
JBrowse link
G Copg2 coatomer protein complex, subunit gamma 2 decreases expression ISO tolcapone results in decreased expression of COPG2 mRNA CTD PMID:24136188 NCBI chr 6:30,747,552...30,873,712
Ensembl chr 6:30,747,553...30,873,729
JBrowse link
G Coq10a coenzyme Q10A decreases expression ISO tolcapone results in decreased expression of COQ10A mRNA CTD PMID:24136188 NCBI chr10:128,198,965...128,204,849
Ensembl chr10:128,198,969...128,204,866
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO tolcapone results in decreased expression of COQ3 mRNA CTD PMID:24136188 NCBI chr 4:21,879,646...21,912,163
Ensembl chr 4:21,879,673...21,912,162
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C affects binding
decreases expression
ISO tolcapone binds to COX6C protein
tolcapone results in decreased expression of COX6C mRNA
CTD PMID:19783845 PMID:24136188 NCBI chr15:35,932,122...35,938,392
Ensembl chr15:35,926,032...35,938,392
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO tolcapone results in decreased expression of COX7A2 mRNA CTD PMID:24136188 NCBI chr 9:79,662,523...79,667,135
Ensembl chr 9:79,662,643...79,667,160
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO tolcapone results in decreased expression of COX7B mRNA CTD PMID:24136188 NCBI chr  X:105,059,306...105,066,056
Ensembl chr  X:105,059,306...105,066,056
JBrowse link
G Cp ceruloplasmin increases expression ISO tolcapone results in increased expression of CP mRNA CTD PMID:24136188 NCBI chr 3:20,011,097...20,063,914
Ensembl chr 3:20,011,218...20,063,309
JBrowse link
G Crem cAMP responsive element modulator decreases expression ISO tolcapone results in decreased expression of CREM mRNA CTD PMID:24136188 NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748
JBrowse link
G Crip2 cysteine rich protein 2 increases expression ISO tolcapone results in increased expression of CRIP2 mRNA CTD PMID:24136188 NCBI chr12:113,103,856...113,109,126
Ensembl chr12:113,103,856...113,109,126
JBrowse link
G Cse1l chromosome segregation 1 like affects binding ISO tolcapone binds to CSE1L protein CTD PMID:19783845 NCBI chr 2:166,747,961...166,788,309
Ensembl chr 2:166,747,960...166,788,309
JBrowse link
G Cstb cystatin B decreases expression ISO tolcapone results in decreased expression of CSTB mRNA CTD PMID:24136188 NCBI chr10:78,261,504...78,263,456
Ensembl chr10:78,261,503...78,263,456
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression ISO Tolcapone results in increased expression of CXCL8 mRNA CTD PMID:32816093 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyc1 cytochrome c-1 affects binding ISO tolcapone binds to CYC1 protein CTD PMID:19783845 NCBI chr15:76,227,711...76,230,460
Ensembl chr15:76,227,723...76,230,460
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO tolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Tolcapone results in decreased activity of CYP1A1 protein
CTD PMID:18493746 PMID:33814510 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO tolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
tolcapone results in increased expression of CYP1A2 mRNA
CTD PMID:18493746 PMID:24136188 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Tolcapone results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression ISO tolcapone results in increased expression of CYP51 mRNA CTD PMID:24136188 NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746
JBrowse link
G Dap death-associated protein increases expression ISO tolcapone results in increased expression of DAP mRNA CTD PMID:24136188 NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487
JBrowse link
G Dctd dCMP deaminase affects binding ISO tolcapone binds to DCTD protein CTD PMID:19783845 NCBI chr 8:48,552,127...48,594,702
Ensembl chr 8:48,552,127...48,606,268
JBrowse link
G Ddost dolichyl-di-phosphooligosaccharide-protein glycotransferase affects binding ISO tolcapone binds to DDOST protein CTD PMID:19783845 NCBI chr 4:138,032,049...138,039,930
Ensembl chr 4:138,032,041...138,039,939
JBrowse link
G Ddx18 DEAD box helicase 18 affects binding ISO tolcapone binds to DDX18 protein CTD PMID:19783845 NCBI chr 1:121,481,564...121,495,709
Ensembl chr 1:121,481,564...121,495,718
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects binding
increases expression
ISO tolcapone binds to DHCR24 protein
tolcapone results in increased expression of DHCR24 mRNA
CTD PMID:19783845 PMID:24136188 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase affects binding ISO tolcapone binds to DHCR7 protein CTD PMID:19783845 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Dmac1 distal membrane arm assembly complex 1 decreases expression ISO tolcapone results in decreased expression of DMAC1 mRNA CTD PMID:24136188 NCBI chr 4:75,195,588...75,196,529
Ensembl chr 4:75,195,591...75,196,542
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression ISO tolcapone results in decreased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr14:78,063,657...78,112,357
Ensembl chr14:78,058,121...78,112,565
JBrowse link
G Dock11 dedicator of cytokinesis 11 decreases expression ISO tolcapone results in decreased expression of DOCK11 mRNA CTD PMID:24136188 NCBI chr  X:35,150,924...35,340,223
Ensembl chr  X:35,152,485...35,340,215
JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase polypeptide 3 decreases expression ISO tolcapone results in decreased expression of DPM3 mRNA CTD PMID:24136188 NCBI chr 3:89,166,567...89,174,386
Ensembl chr 3:89,166,665...89,174,386
JBrowse link
G Dpy30 dpy-30, histone methyltransferase complex regulatory subunit decreases expression ISO tolcapone results in decreased expression of DPY30 mRNA CTD PMID:24136188 NCBI chr17:74,606,469...74,630,939
Ensembl chr17:74,606,469...74,630,939
JBrowse link
G Dtymk deoxythymidylate kinase decreases expression ISO tolcapone results in decreased expression of DTYMK mRNA CTD PMID:24136188 NCBI chr 1:93,720,298...93,730,246
Ensembl chr 1:93,720,298...93,729,656
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression ISO tolcapone results in decreased expression of DYNLL1 mRNA CTD PMID:24136188 NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058
JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression ISO tolcapone results in decreased expression of DYNLT3 mRNA CTD PMID:24136188 NCBI chr  X:9,520,509...9,529,222
Ensembl chr  X:9,520,506...9,529,242
JBrowse link
G Ebp EBP cholestenol delta-isomerase increases expression ISO tolcapone results in increased expression of EBP mRNA CTD PMID:24136188 NCBI chr  X:8,051,568...8,059,751
Ensembl chr  X:8,051,568...8,059,751
JBrowse link
G Echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial affects binding ISO tolcapone binds to ECHS1 protein CTD PMID:19783845 NCBI chr 7:139,685,623...139,696,334
Ensembl chr 7:139,685,623...139,696,389
JBrowse link
G Eloc elongin C decreases expression ISO tolcapone results in decreased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 1:16,711,949...16,727,652
Ensembl chr 1:16,711,949...16,727,266
JBrowse link
G Ereg epiregulin decreases expression ISO Tolcapone results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G F5 coagulation factor V increases expression ISO tolcapone results in increased expression of F5 mRNA CTD PMID:24136188 NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846
JBrowse link
G Fam162a family with sequence similarity 162, member A affects binding ISO tolcapone binds to FAM162A protein CTD PMID:19783845 NCBI chr16:35,864,214...35,891,931
Ensembl chr16:35,864,131...35,891,964
JBrowse link
G Fbll1 fibrillarin-like 1 affects binding ISO tolcapone binds to FBLL1 protein CTD PMID:19783845 NCBI chr11:35,688,207...35,689,711
Ensembl chr11:35,688,209...35,689,711
JBrowse link
G Fcf1 FCF1 rRNA processing protein decreases expression ISO tolcapone results in decreased expression of FCF1 mRNA CTD PMID:24136188 NCBI chr12:85,017,704...85,030,077
Ensembl chr12:85,017,671...85,030,077
JBrowse link
G Fga fibrinogen alpha chain affects binding ISO tolcapone binds to FGA protein CTD PMID:19783845 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 decreases expression ISO tolcapone results in decreased expression of FMC1 mRNA CTD PMID:24136188 NCBI chr 6:38,511,796...38,516,384
Ensembl chr 6:38,510,437...38,516,384
JBrowse link
G Gcdh glutaryl-Coenzyme A dehydrogenase affects binding ISO tolcapone binds to GCDH protein CTD PMID:19783845 NCBI chr 8:85,613,016...85,629,378
Ensembl chr 8:85,613,022...85,620,550
JBrowse link
G Glg1 golgi apparatus protein 1 affects binding ISO tolcapone binds to GLG1 protein CTD PMID:19783845 NCBI chr 8:111,879,916...111,985,842
Ensembl chr 8:111,881,053...111,985,848
JBrowse link
G Gm20348 predicted gene, 20348 decreases expression ISO Tolcapone results in decreased expression of TP53I3 mRNA CTD PMID:24136188 NCBI chr12:4,860,475...4,867,155
Ensembl chr12:4,860,494...4,867,142
JBrowse link
G Gm5617 predicted gene 5617 decreases expression ISO Tolcapone results in decreased expression of C8H11ORF71 mRNA CTD PMID:24136188 NCBI chr 9:48,406,643...48,407,275
Ensembl chr 9:48,406,742...48,407,272
JBrowse link
G Gmfg glia maturation factor, gamma decreases expression ISO tolcapone results in decreased expression of GMFG mRNA CTD PMID:24136188 NCBI chr 7:28,136,894...28,147,655
Ensembl chr 7:28,136,872...28,147,658
JBrowse link
G Gng10 guanine nucleotide binding protein (G protein), gamma 10 decreases expression ISO tolcapone results in decreased expression of GNG10 mRNA CTD PMID:24136188 NCBI chr 4:59,035,156...59,041,899
Ensembl chr 4:59,035,088...59,041,903
JBrowse link
G Gng5 G protein subunit gamma 5 decreases expression ISO tolcapone results in decreased expression of GNG5 mRNA CTD PMID:24136188 NCBI chr 3:146,205,591...146,211,298
Ensembl chr 3:146,205,562...146,211,327
JBrowse link
G Gpc3 glypican 3 affects binding ISO tolcapone binds to GPC3 protein CTD PMID:19783845 NCBI chr  X:51,361,303...51,702,851
Ensembl chr  X:51,361,303...51,702,827
JBrowse link
G Gtf2h5 general transcription factor IIH, polypeptide 5 decreases expression ISO tolcapone results in decreased expression of GTF2H5 mRNA CTD PMID:24136188 NCBI chr17:6,130,103...6,135,763
Ensembl chr17:6,130,061...6,136,792
JBrowse link
G H2az2 H2A.Z histone variant 2 affects binding ISO Tolcapone binds to H2AZ2 protein CTD PMID:19783845 NCBI chr11:6,377,226...6,394,511
Ensembl chr11:6,377,229...6,394,443
JBrowse link
G H4c8 H4 clustered histone 8 decreases expression ISO Tolcapone results in decreased expression of HIST1H4B mRNA CTD PMID:24136188 NCBI chr13:23,715,214...23,715,648
Ensembl chr13:23,715,220...23,715,689
JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain affects binding ISO tolcapone binds to HBB protein CTD PMID:19783845
G Hc hemolytic complement increases expression ISO tolcapone results in increased expression of C5 mRNA CTD PMID:24136188 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450
JBrowse link
G Higd1a HIG1 domain family, member 1A decreases expression ISO tolcapone results in decreased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 9:121,677,623...121,686,862
Ensembl chr 9:121,677,629...121,687,428
JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 decreases expression ISO tolcapone results in decreased expression of HINT3 mRNA CTD PMID:24136188 NCBI chr10:30,479,191...30,499,526
Ensembl chr10:30,484,137...30,505,628
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 affects binding ISO tolcapone binds to HNRNPH1 protein CTD PMID:19783845 NCBI chr11:50,266,084...50,277,355
Ensembl chr11:50,267,817...50,277,355
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 affects binding ISO tolcapone binds to HSD17B11 protein CTD PMID:19783845 NCBI chr 5:104,137,631...104,169,662
Ensembl chr 5:104,137,628...104,169,785
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 affects binding ISO tolcapone binds to HSD17B12 protein CTD PMID:19783845 NCBI chr 2:93,863,042...93,988,254
Ensembl chr 2:93,863,034...93,988,309
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 affects binding ISO tolcapone binds to HSD17B13 protein CTD PMID:19783845 NCBI chr 5:104,103,308...104,125,254
Ensembl chr 5:104,103,306...104,125,276
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects binding ISO tolcapone binds to HSD17B4 protein CTD PMID:19783845 NCBI chr18:50,261,268...50,329,337
Ensembl chr18:50,261,268...50,329,336
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression ISO tolcapone results in increased expression of HSDL2 mRNA CTD PMID:24136188 NCBI chr 4:59,581,515...59,618,694
Ensembl chr 4:59,581,563...59,618,689
JBrowse link
G Iftap intraflagellar transport associated protein decreases expression ISO Tolcapone results in decreased expression of IFTAP mRNA CTD PMID:24136188 NCBI chr 2:101,391,124...101,459,376
Ensembl chr 2:101,391,126...101,479,877
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO tolcapone results in increased expression of IGFBP1 mRNA CTD PMID:24136188 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Il24 interleukin 24 decreases expression ISO Tolcapone results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191
JBrowse link
G Ipo7 importin 7 affects binding ISO tolcapone binds to IPO7 protein CTD PMID:19783845 NCBI chr 7:109,617,522...109,655,816
Ensembl chr 7:109,617,481...109,655,816
JBrowse link
G Itm2a integral membrane protein 2A affects binding ISO tolcapone binds to ITM2A protein CTD PMID:19783845 NCBI chr  X:106,440,801...106,446,966
Ensembl chr  X:106,440,705...106,446,982
JBrowse link
G Jagn1 jagunal homolog 1 affects binding ISO tolcapone binds to JAGN1 protein CTD PMID:19783845 NCBI chr 6:113,419,478...113,425,190
Ensembl chr 6:113,419,530...113,425,190
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO tolcapone results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kng1 kininogen 1 increases expression ISO Tolcapone results in increased expression of KNG1 mRNA CTD PMID:24136188 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
JBrowse link
G Lage3 L antigen family, member 3 decreases expression ISO tolcapone results in decreased expression of LAGE3 mRNA CTD PMID:24136188 NCBI chr  X:73,395,768...73,397,224
Ensembl chr  X:73,394,882...73,397,224
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression ISO tolcapone results in increased expression of LBP mRNA CTD PMID:24136188 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772
JBrowse link
G Lrrc59 leucine rich repeat containing 59 affects binding ISO tolcapone binds to LRRC59 protein CTD PMID:19783845 NCBI chr11:94,520,603...94,536,049
Ensembl chr11:94,520,593...94,536,042
JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO tolcapone results in decreased expression of LSM3 mRNA CTD PMID:24136188 NCBI chr 6:91,493,017...91,499,602
Ensembl chr 6:91,492,910...91,499,607
JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO tolcapone results in decreased expression of LSM5 mRNA CTD PMID:24136188 NCBI chr 6:56,678,048...56,681,684
Ensembl chr 6:56,678,048...56,681,695
JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO tolcapone results in decreased expression of LSM7 mRNA CTD PMID:24136188 NCBI chr10:80,688,659...80,691,043
Ensembl chr10:80,688,655...80,691,043
JBrowse link
G Magoh mago homolog, exon junction complex core component decreases expression ISO tolcapone results in decreased expression of MAGOH mRNA CTD PMID:24136188 NCBI chr 4:107,736,952...107,744,621
Ensembl chr 4:107,736,952...107,744,621
JBrowse link
G Masp1 MBL associated serine protease 1 increases expression ISO tolcapone results in increased expression of MASP1 mRNA CTD PMID:24136188 NCBI chr16:23,261,778...23,340,127
Ensembl chr16:23,268,167...23,339,565
JBrowse link
G Matr3 matrin 3 decreases expression ISO tolcapone results in decreased expression of MATR3 mRNA CTD PMID:24136188 NCBI chr18:35,686,462...35,724,526
Ensembl chr18:35,695,191...35,726,888
JBrowse link
G Mcee methylmalonyl CoA epimerase decreases expression ISO tolcapone results in decreased expression of MCEE mRNA CTD PMID:24136188 NCBI chr 7:64,042,370...64,061,869
Ensembl chr 7:64,042,355...64,061,873
JBrowse link
G Mcts1 malignant T cell amplified sequence 1 decreases expression ISO tolcapone results in decreased expression of MCTS1 mRNA CTD PMID:24136188 NCBI chr  X:37,653,682...37,702,401
Ensembl chr  X:37,689,455...37,702,303
JBrowse link
G Med21 mediator complex subunit 21 decreases expression ISO tolcapone results in decreased expression of MED21 mRNA CTD PMID:24136188 NCBI chr 6:146,544,077...146,552,098
Ensembl chr 6:146,544,045...146,552,230
JBrowse link
G Med28 mediator complex subunit 28 decreases expression ISO tolcapone results in decreased expression of MED28 mRNA CTD PMID:24136188 NCBI chr 5:45,677,571...45,686,626
Ensembl chr 5:45,677,571...45,686,618
JBrowse link
G Med31 mediator complex subunit 31 decreases expression ISO tolcapone results in decreased expression of MED31 mRNA CTD PMID:24136188 NCBI chr11:72,102,550...72,106,418
Ensembl chr11:72,102,550...72,106,418
JBrowse link
G Met met proto-oncogene increases expression ISO Tolcapone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mettl5 methyltransferase 5, N6-adenosine decreases expression ISO tolcapone results in decreased expression of METTL5 mRNA CTD PMID:24136188 NCBI chr 2:69,701,539...69,717,961
Ensembl chr 2:69,701,542...69,715,959
JBrowse link
G Mfsd5 major facilitator superfamily domain containing 5 decreases expression ISO tolcapone results in decreased expression of MFSD5 mRNA CTD PMID:24136188 NCBI chr15:102,187,891...102,190,179
Ensembl chr15:102,187,889...102,190,189
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 affects binding ISO tolcapone binds to MGST1 protein CTD PMID:19783845 NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753
JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 decreases expression ISO tolcapone results in decreased expression of MIA3 mRNA CTD PMID:24136188 NCBI chr 1:183,107,091...183,151,091
Ensembl chr 1:183,107,682...183,150,894
JBrowse link
G Mkks McKusick-Kaufman syndrome decreases expression ISO tolcapone results in decreased expression of MKKS mRNA CTD PMID:24136188 NCBI chr 2:136,715,700...136,733,422
Ensembl chr 2:136,715,700...136,733,309
JBrowse link
G Mkrn1 makorin, ring finger protein, 1 decreases expression ISO tolcapone results in decreased expression of MKRN1 mRNA CTD PMID:24136188 NCBI chr 6:39,374,738...39,400,480
Ensembl chr 6:39,374,738...39,397,396
JBrowse link
G Mmadhc methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria decreases expression ISO tolcapone results in decreased expression of MMADHC mRNA CTD PMID:24136188 NCBI chr 2:50,169,893...50,189,033
Ensembl chr 2:50,169,893...50,186,813
JBrowse link
G Mrpl1 mitochondrial ribosomal protein L1 decreases expression ISO tolcapone results in decreased expression of MRPL1 mRNA CTD PMID:24136188 NCBI chr 5:96,357,357...96,414,586
Ensembl chr 5:96,357,352...96,414,586
JBrowse link
G Mrpl13 mitochondrial ribosomal protein L13 decreases expression ISO tolcapone results in decreased expression of MRPL13 mRNA CTD PMID:24136188 NCBI chr15:55,397,491...55,420,708
Ensembl chr15:55,397,490...55,421,144
JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 decreases expression ISO tolcapone results in decreased expression of MRPL14 mRNA CTD PMID:24136188 NCBI chr17:45,991,689...46,009,421
Ensembl chr17:45,997,248...46,009,421
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 decreases expression ISO tolcapone results in decreased expression of MRPL18 mRNA CTD PMID:24136188 NCBI chr17:13,130,232...13,136,674
Ensembl chr17:13,130,236...13,135,232
JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 decreases expression ISO tolcapone results in decreased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 4:155,887,335...155,893,288
Ensembl chr 4:155,887,335...155,894,432
JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 decreases expression ISO tolcapone results in decreased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr11:58,060,850...58,070,406
Ensembl chr11:58,062,487...58,070,391
JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 decreases expression ISO tolcapone results in decreased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 7:142,086,423...142,094,484
Ensembl chr 7:142,086,423...142,094,484
JBrowse link
G Mrpl30 mitochondrial ribosomal protein L30 decreases expression ISO tolcapone results in decreased expression of MRPL30 mRNA CTD PMID:24136188 NCBI chr 1:37,929,558...37,937,419
Ensembl chr 1:37,929,558...37,937,616
JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 decreases expression ISO tolcapone results in decreased expression of MRPL32 mRNA CTD PMID:24136188 NCBI chr13:14,784,886...14,787,622
Ensembl chr13:14,782,769...14,787,750
JBrowse link
G Mrpl36 mitochondrial ribosomal protein L36 decreases expression ISO tolcapone results in decreased expression of MRPL36 mRNA CTD PMID:24136188 NCBI chr13:73,479,128...73,480,297
Ensembl chr13:73,476,632...73,480,297
JBrowse link
G Mrpl40 mitochondrial ribosomal protein L40 decreases expression ISO tolcapone results in decreased expression of MRPL40 mRNA CTD PMID:24136188 NCBI chr16:18,690,767...18,695,875
Ensembl chr16:18,690,768...18,695,612
JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 decreases expression ISO tolcapone results in decreased expression of MRPL53 mRNA CTD PMID:24136188 NCBI chr 6:83,086,089...83,086,913
Ensembl chr 6:83,086,021...83,086,920
JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 decreases expression ISO tolcapone results in decreased expression of MRPS14 mRNA CTD PMID:24136188 NCBI chr 1:160,022,785...160,028,756
Ensembl chr 1:160,022,785...160,029,740
JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C decreases expression ISO tolcapone results in decreased expression of MRPS18C mRNA CTD PMID:24136188 NCBI chr 5:100,946,625...100,952,333
Ensembl chr 5:100,946,493...100,952,337
JBrowse link
G Mrps24 mitochondrial ribosomal protein S24 decreases expression ISO tolcapone results in decreased expression of MRPS24 mRNA CTD PMID:24136188 NCBI chr11:5,653,982...5,657,701
Ensembl chr11:5,653,983...5,665,680
JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 decreases expression ISO tolcapone results in decreased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 6:39,778,738...39,787,870
Ensembl chr 6:39,778,738...39,787,922
JBrowse link
G Mrps36 mitochondrial ribosomal protein S36 decreases expression ISO Tolcapone results in decreased expression of KGD4 mRNA CTD PMID:24136188 NCBI chr13:100,872,448...100,881,167
Ensembl chr13:100,872,463...100,881,167
JBrowse link
G Mtap methylthioadenosine phosphorylase affects binding ISO tolcapone binds to MTAP protein CTD PMID:19783845 NCBI chr 4:89,055,607...89,099,327
Ensembl chr 4:89,055,359...89,099,318
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO tolcapone results in increased expression of MTTP protein CTD PMID:29688484 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
JBrowse link
G Mvk mevalonate kinase increases expression ISO tolcapone results in increased expression of MVK mRNA CTD PMID:24136188 NCBI chr 5:114,582,324...114,598,652
Ensembl chr 5:114,582,330...114,598,652
JBrowse link
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit decreases expression ISO tolcapone results in decreased expression of NAA20 mRNA CTD PMID:24136188 NCBI chr 2:145,743,454...145,758,345
Ensembl chr 2:145,744,019...145,758,345
JBrowse link
G Nat10 N-acetyltransferase 10 affects binding ISO tolcapone binds to NAT10 protein CTD PMID:19783845 NCBI chr 2:103,551,603...103,593,292
Ensembl chr 2:103,551,601...103,591,615
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 decreases expression ISO tolcapone results in decreased expression of NDUFA1 mRNA CTD PMID:24136188 NCBI chr  X:36,451,241...36,454,891
Ensembl chr  X:36,451,241...36,454,816
JBrowse link
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 decreases expression ISO tolcapone results in decreased expression of NDUFA2 mRNA CTD PMID:24136188 NCBI chr18:36,875,385...36,877,640
Ensembl chr18:36,875,385...36,877,610
JBrowse link
G Ndufa6 NADH:ubiquinone oxidoreductase subunit A6 decreases expression ISO tolcapone results in decreased expression of NDUFA6 mRNA CTD PMID:24136188 NCBI chr15:82,234,342...82,238,438
Ensembl chr15:82,234,341...82,238,523
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 decreases expression ISO tolcapone results in decreased expression of NDUFA7 mRNA CTD PMID:24136188 NCBI chr17:34,043,546...34,057,290
Ensembl chr17:34,043,546...34,057,291
JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 affects binding ISO tolcapone binds to NDUFA9 protein CTD PMID:19783845 NCBI chr 6:126,798,826...126,826,107
Ensembl chr 6:126,798,684...126,826,099
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO tolcapone results in decreased expression of NDUFB6 mRNA CTD PMID:24136188 NCBI chr 4:40,270,591...40,279,421
Ensembl chr 4:40,270,591...40,279,421
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 decreases expression ISO tolcapone results in decreased expression of NDUFC2 mRNA CTD PMID:24136188 NCBI chr 7:97,049,210...97,057,007
Ensembl chr 7:97,049,210...97,057,009
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase core subunit S4 decreases expression ISO tolcapone results in decreased expression of NDUFS4 mRNA CTD PMID:24136188 NCBI chr13:114,424,331...114,524,630
Ensembl chr13:114,424,331...114,524,794
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase core subunit S5 decreases expression ISO tolcapone results in decreased expression of NDUFS5 mRNA CTD PMID:24136188 NCBI chr 4:123,606,503...123,611,979
Ensembl chr 4:123,606,503...123,611,995
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression ISO tolcapone results in decreased expression of NFE2L2 mRNA CTD PMID:28526448 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nipsnap1 nipsnap homolog 1 affects binding ISO tolcapone binds to NIPSNAP1 protein CTD PMID:19783845 NCBI chr11:4,823,951...4,844,201
Ensembl chr11:4,823,951...4,844,200
JBrowse link
G Nipsnap2 nipsnap homolog 2 affects binding ISO tolcapone binds to NIPSNAP2 protein CTD PMID:19783845 NCBI chr 5:129,802,080...129,835,391
Ensembl chr 5:129,802,127...129,835,391
JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 decreases expression ISO tolcapone results in decreased expression of NME3 mRNA CTD PMID:24136188 NCBI chr17:25,115,474...25,116,505
Ensembl chr17:25,115,474...25,116,496
JBrowse link
G Nop56 NOP56 ribonucleoprotein affects binding ISO tolcapone binds to NOP56 protein CTD PMID:19783845 NCBI chr 2:130,112,904...130,121,233
Ensembl chr 2:130,116,350...130,121,233
JBrowse link
G Nphp1 nephronophthisis 1 (juvenile) homolog (human) decreases expression ISO tolcapone results in decreased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 2:127,582,652...127,630,833
Ensembl chr 2:127,582,652...127,630,817
JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor increases expression ISO tolcapone results in increased expression of NPLOC4 mRNA CTD PMID:24136188 NCBI chr11:120,270,624...120,328,526
Ensembl chr11:120,271,196...120,328,534
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO tolcapone results in decreased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Nupr2 nuclear protein transcriptional regulator 2 decreases expression ISO tolcapone results in decreased expression of NUPR2 mRNA CTD PMID:24136188 NCBI chr 5:129,937,381...129,942,629
Ensembl chr 5:129,937,381...129,942,630
JBrowse link
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide affects binding ISO tolcapone binds to P4HA1 protein CTD PMID:19783845 NCBI chr10:59,159,019...59,209,126
Ensembl chr10:59,159,118...59,209,126
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO tolcapone results in decreased expression of PCNA mRNA CTD PMID:24136188 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pcx pyruvate carboxylase affects binding ISO tolcapone binds to PC protein CTD PMID:19783845 NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1, choline, alpha isoform affects binding ISO tolcapone binds to PCYT1A protein CTD PMID:19783845 NCBI chr16:32,249,739...32,293,883
Ensembl chr16:32,249,739...32,293,888
JBrowse link
G Pdzd11 PDZ domain containing 11 decreases expression ISO tolcapone results in decreased expression of PDZD11 mRNA CTD PMID:24136188 NCBI chr  X:99,665,949...99,673,667
Ensembl chr  X:99,666,489...99,670,174
JBrowse link
G Pfdn1 prefoldin 1 decreases expression ISO tolcapone results in decreased expression of PFDN1 mRNA CTD PMID:24136188 NCBI chr18:36,536,732...36,587,548
Ensembl chr18:36,536,729...36,587,577
JBrowse link
G Pfdn5 prefoldin 5 decreases expression ISO tolcapone results in decreased expression of PFDN5 mRNA CTD PMID:24136188 NCBI chr15:102,234,551...102,239,925
Ensembl chr15:102,234,551...102,240,308
JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO tolcapone results in increased expression of PGM1 mRNA CTD PMID:24136188 NCBI chr 4:99,786,648...99,844,491
Ensembl chr 4:99,786,611...99,844,491
JBrowse link
G Pgr progesterone receptor multiple interactions ISO tolcapone binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P decreases expression ISO tolcapone results in decreased expression of PIGP mRNA CTD PMID:24136188 NCBI chr16:94,159,622...94,171,874
Ensembl chr16:94,159,622...94,172,701
JBrowse link
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S affects binding ISO tolcapone binds to PIGS protein CTD PMID:19783845 NCBI chr11:78,219,272...78,233,602
Ensembl chr11:78,219,241...78,233,608
JBrowse link
G Pin4 peptidyl-prolyl cis/trans isomerase, NIMA-interacting, 4 (parvulin) decreases expression ISO tolcapone results in decreased expression of PIN4 mRNA CTD PMID:24136188 NCBI chr  X:101,163,075...101,171,276
Ensembl chr  X:101,163,053...101,171,275
JBrowse link
G Plin2 perilipin 2 affects binding ISO tolcapone binds to PLIN2 protein CTD PMID:19783845 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Plin3 perilipin 3 affects binding ISO tolcapone binds to PLIN3 protein CTD PMID:19783845 NCBI chr17:56,585,962...56,597,511
Ensembl chr17:56,584,476...56,599,873
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression ISO tolcapone results in increased expression of PNPLA2 mRNA CTD PMID:24136188 NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656
JBrowse link
G Polr1h RNA polymerase I subunit H decreases expression ISO Tolcapone results in decreased expression of POLR1H mRNA CTD PMID:24136188 NCBI chr17:37,265,250...37,269,417
Ensembl chr17:37,265,248...37,269,451
JBrowse link
G Polr2g polymerase (RNA) II (DNA directed) polypeptide G decreases expression ISO tolcapone results in decreased expression of POLR2G mRNA CTD PMID:24136188 NCBI chr19:8,770,493...8,775,921
Ensembl chr19:8,770,491...8,775,941
JBrowse link
G Prpf8 pre-mRNA processing factor 8 affects binding ISO tolcapone binds to PRPF8 protein CTD PMID:19783845 NCBI chr11:75,377,603...75,400,273
Ensembl chr11:75,377,642...75,400,275
JBrowse link
G Prxl2a peroxiredoxin like 2A affects binding ISO tolcapone binds to PRXL2A protein CTD PMID:19783845 NCBI chr14:40,715,692...40,735,790
Ensembl chr14:40,715,697...40,735,745
JBrowse link
G Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 affects binding ISO tolcapone binds to PSMC5 protein CTD PMID:19783845 NCBI chr11:106,147,011...106,153,938
Ensembl chr11:106,146,980...106,153,946
JBrowse link
G Psme2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) affects binding ISO tolcapone binds to PSME2 protein CTD PMID:19783845 NCBI chr14:55,824,897...55,828,558
Ensembl chr14:55,824,898...55,828,570
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Tolcapone results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptrh2 peptidyl-tRNA hydrolase 2 affects binding ISO tolcapone binds to PTRH2 protein CTD PMID:19783845 NCBI chr11:86,574,900...86,583,283
Ensembl chr11:86,574,811...86,583,283
JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit decreases expression ISO tolcapone results in decreased expression of RAMAC mRNA CTD PMID:24136188 NCBI chr 7:81,412,701...81,419,238
Ensembl chr 7:81,412,673...81,419,239
JBrowse link
G Ran RAN, member RAS oncogene family affects binding ISO tolcapone binds to RAN protein CTD PMID:19783845 NCBI chr 5:129,097,264...129,101,388
Ensembl chr 5:129,097,133...129,101,387
JBrowse link
G Rap1a RAS-related protein 1a decreases expression ISO tolcapone results in decreased expression of RAP1A mRNA CTD PMID:24136188 NCBI chr 3:105,634,576...105,708,740
Ensembl chr 3:105,634,583...105,708,652
JBrowse link
G Rbis ribosomal biogenesis factor decreases expression ISO Tolcapone results in decreased expression of RBIS mRNA CTD PMID:24136188 NCBI chr 3:14,671,349...14,676,419
Ensembl chr 3:14,671,344...14,676,345
JBrowse link
G Rbm8a RNA binding motif protein 8a decreases expression ISO tolcapone results in decreased expression of RBM8A mRNA CTD PMID:24136188 NCBI chr 3:96,537,244...96,541,107
Ensembl chr 3:96,537,249...96,541,107
JBrowse link
G Rbp1 retinol binding protein 1, cellular decreases expression ISO tolcapone results in decreased expression of RBP1 mRNA CTD PMID:24136188 NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628
JBrowse link
G Reep6 receptor accessory protein 6 affects binding ISO tolcapone binds to REEP6 protein CTD PMID:19783845 NCBI chr10:80,165,831...80,172,275
Ensembl chr10:80,165,787...80,172,275
JBrowse link
G Rnf7 ring finger protein 7 decreases expression ISO tolcapone results in decreased expression of RNF7 mRNA CTD PMID:24136188 NCBI chr 9:96,352,990...96,360,728
Ensembl chr 9:96,352,990...96,360,728
JBrowse link
G Rnls renalase, FAD-dependent amine oxidase decreases expression ISO tolcapone results in decreased expression of RNLS mRNA CTD PMID:24136188 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665
JBrowse link
G Romo1 reactive oxygen species modulator 1 decreases expression ISO tolcapone results in decreased expression of ROMO1 mRNA CTD PMID:24136188 NCBI chr 2:155,986,073...155,987,714
Ensembl chr 2:155,985,959...155,987,717
JBrowse link
G Rpa3 replication protein A3 decreases expression ISO tolcapone results in decreased expression of RPA3 mRNA CTD PMID:24136188 NCBI chr 6:8,255,936...8,259,141
Ensembl chr 6:8,255,936...8,259,173
JBrowse link
G Rpl10a ribosomal protein L10A affects binding ISO tolcapone binds to RPL10A protein CTD PMID:19783845 NCBI chr17:28,547,557...28,550,007
Ensembl chr17:28,547,445...28,550,007
JBrowse link
G Rpl15 ribosomal protein L15 affects binding ISO tolcapone binds to RPL15 protein CTD PMID:19783845 NCBI chr14:4,198,710...4,201,873
Ensembl chr14:4,198,305...4,201,873
JBrowse link
G Rpl18a ribosomal protein L18A affects binding ISO tolcapone binds to RPL18A protein CTD PMID:19783845 NCBI chr 8:71,347,366...71,350,087
Ensembl chr 8:71,347,366...71,350,056
JBrowse link
G Rpl22 ribosomal protein L22 affects binding ISO tolcapone binds to RPL22 protein CTD PMID:19783845 NCBI chr 4:152,408,893...152,418,539
Ensembl chr 4:152,410,199...152,418,528
JBrowse link
G Rpl22l1 ribosomal protein L22 like 1 decreases expression ISO tolcapone results in decreased expression of RPL22L1 mRNA CTD PMID:24136188 NCBI chr 3:28,859,660...28,861,573
Ensembl chr 3:28,859,585...28,861,573
JBrowse link
G Rpl23 ribosomal protein L23 affects binding ISO tolcapone binds to RPL23 protein CTD PMID:19783845 NCBI chr11:97,668,352...97,673,265
Ensembl chr11:97,668,353...97,673,263
JBrowse link
G Rpl35a ribosomal protein L35A decreases expression ISO tolcapone results in decreased expression of RPL35A mRNA CTD PMID:24136188 NCBI chr16:32,876,823...32,880,559
Ensembl chr16:32,876,823...32,880,559
JBrowse link
G Rpl36a ribosomal protein L36A decreases expression ISO tolcapone results in decreased expression of RPL36A mRNA CTD PMID:24136188 NCBI chr  X:133,486,403...133,488,811
Ensembl chr  X:133,486,403...133,488,811
JBrowse link
G Rpl41 ribosomal protein L41 decreases expression ISO tolcapone results in decreased expression of RPL41 mRNA CTD PMID:24136188 NCBI chr10:128,383,979...128,385,037
Ensembl chr10:128,383,983...128,385,174
JBrowse link
G Rpl7a ribosomal protein L7A affects binding ISO tolcapone binds to RPL7A protein CTD PMID:19783845 NCBI chr 2:26,800,697...26,803,330
Ensembl chr 2:26,800,776...26,803,330
JBrowse link
G Rpl7l1 ribosomal protein L7-like 1 affects binding ISO tolcapone binds to RPL7L1 protein CTD PMID:19783845 NCBI chr17:47,084,833...47,093,582
Ensembl chr17:47,084,833...47,093,598
JBrowse link
G Rpl9 ribosomal protein L9 decreases expression ISO tolcapone results in decreased expression of RPL9 mRNA CTD PMID:24136188 NCBI chr 5:65,545,707...65,548,774
Ensembl chr 5:65,545,707...65,548,787
JBrowse link
G Rpp21 ribonuclease P 21 subunit decreases expression ISO tolcapone results in decreased expression of RPP21 mRNA CTD PMID:24136188 NCBI chr17:36,566,565...36,568,738
Ensembl chr17:36,566,537...36,568,961
JBrowse link
G Rps11 ribosomal protein S11 affects binding ISO tolcapone binds to RPS11 protein CTD PMID:19783845 NCBI chr 7:44,771,812...44,773,813
Ensembl chr 7:44,771,803...44,773,863
JBrowse link
G Rps14 ribosomal protein S14 affects binding ISO tolcapone binds to RPS14 protein CTD PMID:19783845 NCBI chr18:60,907,668...60,911,618
Ensembl chr18:60,880,170...60,911,618
JBrowse link
G Rps15a ribosomal protein S15A decreases expression ISO tolcapone results in decreased expression of RPS15A mRNA CTD PMID:24136188 NCBI chr 7:117,703,597...117,715,370
Ensembl chr 7:117,703,595...117,715,411
JBrowse link
G Rps20 ribosomal protein S20 affects binding ISO tolcapone binds to RPS20 protein CTD PMID:19783845 NCBI chr 4:3,831,334...3,835,600
Ensembl chr 4:3,831,334...3,835,665
JBrowse link
G Rps21 ribosomal protein S21 decreases expression ISO tolcapone results in decreased expression of RPS21 mRNA CTD PMID:24136188 NCBI chr 2:179,899,172...179,900,237
Ensembl chr 2:179,899,170...179,900,238
JBrowse link
G Rps24 ribosomal protein S24 decreases expression ISO tolcapone results in decreased expression of RPS24 mRNA CTD PMID:24136188 NCBI chr14:24,540,786...24,545,925
Ensembl chr14:24,537,193...24,547,027
JBrowse link
G Rps25 ribosomal protein S25 decreases expression ISO tolcapone results in decreased expression of RPS25 mRNA CTD PMID:24136188 NCBI chr 9:44,319,011...44,321,703
Ensembl chr 9:44,318,436...44,321,724
JBrowse link
G Rps27 ribosomal protein S27 decreases expression ISO Tolcapone results in decreased expression of RPS27 mRNA CTD PMID:24136188 NCBI chr 3:90,119,974...90,120,955
Ensembl chr 3:90,119,829...90,120,958
JBrowse link
G Rps27a ribosomal protein S27A affects binding ISO tolcapone binds to RPS27A protein CTD PMID:19783845 NCBI chr11:29,495,842...29,498,040
Ensembl chr11:29,495,846...29,498,109
JBrowse link
G S100a10 S100 calcium binding protein A10 (calpactin) decreases expression ISO tolcapone results in decreased expression of S100A10 mRNA CTD PMID:24136188 NCBI chr 3:93,462,424...93,471,952
Ensembl chr 3:93,462,387...93,471,950
JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO tolcapone results in increased expression of SC5D mRNA CTD PMID:24136188 NCBI chr 9:42,162,888...42,175,607
Ensembl chr 9:42,162,891...42,175,552
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 affects binding
decreases expression
ISO tolcapone binds to SCD protein
tolcapone results in decreased expression of SCD1 mRNA
CTD PMID:19783845 PMID:24136188 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) affects binding ISO tolcapone binds to SDHA protein CTD PMID:19783845 NCBI chr13:74,470,374...74,498,359
Ensembl chr13:74,470,373...74,498,399
JBrowse link
G Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) affects binding ISO tolcapone binds to SDHB protein CTD PMID:19783845 NCBI chr 4:140,688,582...140,706,509
Ensembl chr 4:140,688,514...140,706,504
JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit affects binding ISO tolcapone binds to SEC11C protein CTD PMID:19783845 NCBI chr18:65,933,649...65,950,731
Ensembl chr18:65,933,586...65,950,755
JBrowse link
G Sec31a SEC31 homolog A, COPII coat complex component affects binding ISO tolcapone binds to SEC31A protein CTD PMID:19783845 NCBI chr 5:100,509,508...100,564,132
Ensembl chr 5:100,509,508...100,564,093
JBrowse link
G Serbp1 serpine1 mRNA binding protein 1 affects binding ISO tolcapone binds to SERBP1 protein CTD PMID:19783845 NCBI chr 6:67,243,963...67,266,286
Ensembl chr 6:67,215,160...67,274,720
JBrowse link
G Sf3b6 splicing factor 3B, subunit 6 affects binding ISO tolcapone binds to SF3B6 protein CTD PMID:19783845 NCBI chr12:4,867,608...4,877,659
Ensembl chr12:4,867,544...4,877,659
JBrowse link
G Sfxn1 sideroflexin 1 affects binding ISO tolcapone binds to SFXN1 protein CTD PMID:19783845 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
JBrowse link
G Sik3 SIK family kinase 3 increases expression ISO tolcapone results in increased expression of SIK3 mRNA CTD PMID:24136188 NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492
JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 affects binding ISO tolcapone binds to SLC1A5 protein CTD PMID:19783845 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199
JBrowse link
G Slc25a1 solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 affects binding ISO tolcapone binds to SLC25A1 protein CTD PMID:19783845 NCBI chr16:17,743,075...17,746,083
Ensembl chr16:17,743,087...17,746,083
JBrowse link
G Slc25a13 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 affects binding ISO tolcapone binds to SLC25A13 protein CTD PMID:19783845 NCBI chr 6:6,041,218...6,217,304
Ensembl chr 6:6,041,218...6,217,173
JBrowse link
G Slc25a4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 affects binding ISO tolcapone binds to SLC25A4 protein CTD PMID:19783845 NCBI chr 8:46,660,205...46,664,099
Ensembl chr 8:46,659,834...46,664,321
JBrowse link
G Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 affects binding ISO tolcapone binds to SLC25A5 protein CTD PMID:19783845 NCBI chr  X:36,059,250...36,062,461
Ensembl chr  X:36,059,304...36,062,460
JBrowse link
G Slc39a7 solute carrier family 39 (zinc transporter), member 7 affects binding ISO tolcapone binds to SLC39A7 protein CTD PMID:19783845 NCBI chr17:34,247,240...34,250,664
Ensembl chr17:34,247,243...34,250,656
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 decreases expression ISO Tolcapone results in decreased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Tolcapone results in decreased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
JBrowse link
G Smim26 small integral membrane protein 26 decreases expression ISO tolcapone results in decreased expression of SMIM26 mRNA CTD PMID:24136188 NCBI chr 2:144,435,985...144,437,286
Ensembl chr 2:144,435,974...144,437,286
JBrowse link
G Snapin SNAP-associated protein decreases expression ISO tolcapone results in decreased expression of SNAPIN mRNA CTD PMID:24136188 NCBI chr 3:90,395,333...90,398,320
Ensembl chr 3:90,395,333...90,398,340
JBrowse link
G Snca synuclein, alpha multiple interactions ISO tolcapone inhibits the reaction [SNCA protein binds to SNCA protein] CTD PMID:20150427 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Snrnp27 small nuclear ribonucleoprotein 27 (U4/U6.U5) decreases expression ISO Tolcapone results in decreased expression of SNRNP27 mRNA CTD PMID:24136188 NCBI chr 6:86,652,151...86,661,473
Ensembl chr 6:86,652,133...86,661,504
JBrowse link
G Snrpb2 U2 small nuclear ribonucleoprotein B decreases expression ISO tolcapone results in decreased expression of SNRPB2 mRNA CTD PMID:24136188 NCBI chr 2:142,904,989...142,913,972
Ensembl chr 2:142,904,959...142,914,773
JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 decreases expression ISO tolcapone results in decreased expression of SNRPD3 mRNA CTD PMID:24136188 NCBI chr10:75,353,852...75,371,300
Ensembl chr10:75,353,385...75,373,215
JBrowse link
G Snrpe small nuclear ribonucleoprotein E decreases expression ISO tolcapone results in decreased expression of SNRPE mRNA CTD PMID:24136188 NCBI chr 1:133,531,609...133,538,018
Ensembl chr 1:133,531,609...133,538,029
JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F decreases expression ISO tolcapone results in decreased expression of SNRPF mRNA CTD PMID:24136188 NCBI chr10:93,418,891...93,425,520
Ensembl chr10:93,418,891...93,425,568
JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G decreases expression ISO tolcapone results in decreased expression of SNRPG mRNA CTD PMID:24136188 NCBI chr 6:86,348,522...86,355,884
Ensembl chr 6:86,348,286...86,356,310
JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases expression ISO tolcapone results in decreased expression of SOD1 mRNA CTD PMID:28526448 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial decreases expression ISO tolcapone results in decreased expression of SOD2 mRNA CTD PMID:28526448 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Srp14 signal recognition particle 14 decreases expression ISO tolcapone results in decreased expression of SRP14 mRNA CTD PMID:24136188 NCBI chr 2:118,306,324...118,310,177
Ensembl chr 2:118,306,331...118,310,192
JBrowse link
G Srprb signal recognition particle receptor, B subunit affects binding ISO tolcapone binds to SRPRB protein CTD PMID:19783845 NCBI chr 9:103,065,232...103,079,264
Ensembl chr 9:103,065,231...103,079,336
JBrowse link
G Ss18l2 SS18, nBAF chromatin remodeling complex subunit like 2 decreases expression ISO tolcapone results in decreased expression of SS18L2 mRNA CTD PMID:24136188 NCBI chr 9:121,539,455...121,541,987
Ensembl chr 9:121,539,395...121,542,454
JBrowse link
G Ssr1 signal sequence receptor, alpha affects binding ISO tolcapone binds to SSR1 protein CTD PMID:19783845 NCBI chr13:38,155,377...38,178,184
Ensembl chr13:38,150,581...38,178,193
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression ISO tolcapone results in decreased expression of STAC3 mRNA CTD PMID:24136188 NCBI chr10:127,337,505...127,344,692
Ensembl chr10:127,337,555...127,344,692
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO tolcapone results in increased expression of STAT3 mRNA CTD PMID:24136188 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 affects binding ISO tolcapone binds to SULT2A1 protein CTD PMID:19783845 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 decreases expression ISO tolcapone results in decreased expression of TAF9 mRNA CTD PMID:24136188 NCBI chr13:100,787,851...100,792,568
Ensembl chr13:100,788,087...100,792,568
Ensembl chr13:100,788,087...100,792,568
JBrowse link
G Tbca tubulin cofactor A decreases expression ISO tolcapone results in decreased expression of TBCA mRNA CTD PMID:24136188 NCBI chr13:94,925,428...94,979,431
Ensembl chr13:94,925,418...94,979,430
JBrowse link
G Tceal8 transcription elongation factor A (SII)-like 8 decreases expression ISO tolcapone results in decreased expression of TCEAL8 mRNA CTD PMID:24136188 NCBI chr  X:135,069,733...135,073,000
Ensembl chr  X:135,069,733...135,073,091
JBrowse link
G Tfr2 transferrin receptor 2 increases expression ISO tolcapone results in increased expression of TFR2 mRNA CTD PMID:24136188 NCBI chr 5:137,568,127...137,586,344
Ensembl chr 5:137,568,102...137,585,743
JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 decreases expression ISO tolcapone results in decreased expression of TIMM10 mRNA CTD PMID:24136188 NCBI chr 2:84,657,365...84,660,557
Ensembl chr 2:84,657,341...84,660,557
JBrowse link
G Timm44 translocase of inner mitochondrial membrane 44 affects binding ISO tolcapone binds to TIMM44 protein CTD PMID:19783845 NCBI chr 8:4,309,731...4,325,905
Ensembl chr 8:4,309,731...4,325,913
JBrowse link
G Timm8b translocase of inner mitochondrial membrane 8B decreases expression ISO tolcapone results in decreased expression of TIMM8B mRNA CTD PMID:24136188 NCBI chr 9:50,515,227...50,516,620
Ensembl chr 9:50,515,210...50,516,620
JBrowse link
G Tk2 thymidine kinase 2, mitochondrial affects binding ISO tolcapone binds to TK2 protein CTD PMID:19783845 NCBI chr 8:104,953,323...104,975,224
Ensembl chr 8:104,953,317...104,975,190
JBrowse link
G Tm2d1 TM2 domain containing 1 decreases expression ISO tolcapone results in decreased expression of TM2D1 mRNA CTD PMID:24136188 NCBI chr 4:98,243,607...98,271,523
Ensembl chr 4:98,243,607...98,271,543
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 affects binding ISO tolcapone binds to TMED10 protein CTD PMID:19783845 NCBI chr12:85,387,388...85,421,491
Ensembl chr12:85,387,388...85,421,621
JBrowse link
G Tmed4 transmembrane p24 trafficking protein 4 affects binding ISO tolcapone binds to TMED4 protein CTD PMID:19783845 NCBI chr11:6,220,714...6,224,837
Ensembl chr11:6,220,369...6,224,870
JBrowse link
G Tmed9 transmembrane p24 trafficking protein 9 affects binding ISO tolcapone binds to TMED9 protein CTD PMID:19783845 NCBI chr13:55,740,948...55,745,510
Ensembl chr13:55,721,545...55,745,510
JBrowse link
G Tmem126a transmembrane protein 126A decreases expression ISO tolcapone results in decreased expression of TMEM126A mRNA CTD PMID:24136188 NCBI chr 7:90,099,908...90,106,411
Ensembl chr 7:90,099,908...90,106,437
JBrowse link
G Tmem126b transmembrane protein 126B decreases expression ISO tolcapone results in decreased expression of TMEM126B mRNA CTD PMID:24136188 NCBI chr 7:90,118,041...90,125,203
Ensembl chr 7:90,116,646...90,125,209
JBrowse link
G Tmem128 transmembrane protein 128 decreases expression ISO tolcapone results in decreased expression of TMEM128 mRNA CTD PMID:24136188 NCBI chr 5:38,417,529...38,426,978
Ensembl chr 5:38,417,529...38,426,978
JBrowse link
G Tmem203 transmembrane protein 203 decreases expression ISO tolcapone results in decreased expression of TMEM203 mRNA CTD PMID:24136188 NCBI chr 2:25,145,451...25,146,364
Ensembl chr 2:25,145,451...25,146,304
JBrowse link
G Tmem238 transmembrane protein 238 decreases expression ISO tolcapone results in decreased expression of TMEM238 mRNA CTD PMID:24136188 NCBI chr 7:4,787,784...4,792,559
Ensembl chr 7:4,787,556...4,792,655
JBrowse link
G Tmem256 transmembrane protein 256 decreases expression ISO tolcapone results in decreased expression of TMEM256 mRNA CTD PMID:24136188 NCBI chr11:69,729,375...69,730,813
Ensembl chr11:69,729,340...69,730,444
JBrowse link
G Tmsb4x thymosin, beta 4, X chromosome decreases expression ISO tolcapone results in decreased expression of TMSB4X mRNA CTD PMID:24136188 NCBI chr  X:165,990,089...165,996,475
Ensembl chr  X:165,990,089...165,992,311
JBrowse link
G Tnfaip8 tumor necrosis factor, alpha-induced protein 8 affects binding ISO tolcapone binds to TNFAIP8 protein CTD PMID:19783845 NCBI chr18:50,112,494...50,226,296
Ensembl chr18:50,112,494...50,240,240
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression ISO tolcapone results in increased expression of TNFRSF1A mRNA CTD PMID:24136188 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 affects binding ISO tolcapone binds to TOMM20 protein CTD PMID:19783845 NCBI chr 8:127,657,414...127,672,671
Ensembl chr 8:127,657,417...127,672,594
JBrowse link
G Tomm40 translocase of outer mitochondrial membrane 40 affects binding ISO tolcapone binds to TOMM40 protein CTD PMID:19783845 NCBI chr 7:19,435,238...19,449,370
Ensembl chr 7:19,435,238...19,449,363
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 affects binding ISO tolcapone binds to TOMM7 protein CTD PMID:19783845 NCBI chr 5:24,043,942...24,049,143
Ensembl chr 5:24,043,942...24,049,159
JBrowse link
G Trappc2l trafficking protein particle complex 2L decreases expression ISO tolcapone results in decreased expression of TRAPPC2L mRNA CTD PMID:24136188 NCBI chr 8:123,338,365...123,342,330
Ensembl chr 8:123,338,379...123,343,399
JBrowse link
G Tspan6 tetraspanin 6 decreases expression ISO tolcapone results in decreased expression of TSPAN6 mRNA CTD PMID:24136188 NCBI chr  X:132,791,817...132,801,957
Ensembl chr  X:132,791,817...132,799,178
JBrowse link
G Tubb6 tubulin, beta 6 class V affects binding ISO tolcapone binds to TUBB6 protein CTD PMID:19783845 NCBI chr18:67,523,801...67,535,819
Ensembl chr18:67,523,787...67,535,819
JBrowse link
G Txndc17 thioredoxin domain containing 17 decreases expression ISO tolcapone results in decreased expression of TXNDC17 mRNA CTD PMID:24136188 NCBI chr11:72,098,380...72,101,313
Ensembl chr11:72,098,373...72,100,841
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 decreases glucuronidation
increases glucuronidation
ISO UGT1A9 protein mutant form results in decreased glucuronidation of tolcapone
UGT1A9 protein results in increased glucuronidation of tolcapone
CTD PMID:16344532 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 affects binding ISO tolcapone binds to UQCRC2 protein CTD PMID:19783845 NCBI chr 7:120,234,412...120,258,746
Ensembl chr 7:120,234,399...120,258,747
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 affects binding ISO tolcapone binds to UQCRFS1 protein CTD PMID:19783845 NCBI chr13:30,724,295...30,729,299
Ensembl chr13:30,724,291...30,729,345
JBrowse link
G Uvrag UV radiation resistance associated gene increases expression ISO tolcapone results in increased expression of UVRAG mRNA CTD PMID:24136188 NCBI chr 7:98,535,949...98,790,373
Ensembl chr 7:98,534,228...98,790,348
JBrowse link
G Vdac2 voltage-dependent anion channel 2 affects binding ISO tolcapone binds to VDAC2 protein CTD PMID:19783845 NCBI chr14:21,881,629...21,895,947
Ensembl chr14:21,875,306...21,895,947
JBrowse link
G Vdac3 voltage-dependent anion channel 3 affects binding ISO tolcapone binds to VDAC3 protein CTD PMID:19783845 NCBI chr 8:23,067,091...23,083,829
Ensembl chr 8:23,067,102...23,083,774
JBrowse link
G Vsnl1 visinin-like 1 affects binding ISO tolcapone binds to VSNL1 protein CTD PMID:19783845 NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
JBrowse link
G Washc3 WASH complex subunit 3 decreases expression ISO tolcapone results in decreased expression of WASHC3 mRNA CTD PMID:24136188 NCBI chr10:88,036,954...88,160,001
Ensembl chr10:88,036,955...88,082,020
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein affects binding ISO tolcapone binds to WFS1 protein CTD PMID:19783845 NCBI chr 5:37,123,448...37,146,326
Ensembl chr 5:37,123,448...37,146,549
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 increases expression ISO Tolcapone results in increased expression of YARS1 mRNA CTD PMID:24136188 NCBI chr 4:129,083,595...129,113,033
Ensembl chr 4:129,083,553...129,113,400
JBrowse link
G Yeats4 YEATS domain containing 4 decreases expression ISO tolcapone results in decreased expression of YEATS4 mRNA CTD PMID:24136188 NCBI chr10:117,051,046...117,060,412
Ensembl chr10:117,051,126...117,060,412
JBrowse link
G Znrf1 zinc and ring finger 1 increases expression ISO tolcapone results in increased expression of ZNRF1 mRNA CTD PMID:24136188 NCBI chr 8:112,262,652...112,352,352
Ensembl chr 8:112,262,729...112,352,662
JBrowse link

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  CHEBI ontology 22210
    role 22195
      application 21777
        pharmaceutical 21192
          drug 21192
            antidyskinesia agent 1531
              L-dopa + 0
              antiparkinson drug + 1161
              apomorphine + 27
              benzatropine + 331
              biperiden + 11
              bromocriptine + 40
              carbidopa 19
              cycrimine + 0
              diphenhydramine + 22
              entacapone + 28
              haloperidol 521
              lisuride + 5
              orphenadrine + 400
              pimozide 6
              pramipexole 10
              procyclidine + 14
              profenamine + 2
              ropinirole 13
paths to the root