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Gene: Thra (thyroid hormone receptor alpha) Mus musculus
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Symbol: Thra
Name: thyroid hormone receptor alpha
Description: Exhibits nuclear receptor activity and nucleic acid binding activity. Involved in several processes, including animal organ development; female mating behavior; and regulation of transcription, DNA-templated. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study thyroid hormone resistance syndrome. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 6 and renal cell carcinoma. Orthologous to human THRA (thyroid hormone receptor alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6430529J03Rik; AW259572; c-erbA-1; c-erbA-alpha; c-erbAalpha; Erba; Nr1a1; nuclear receptor subfamily 1 group A member 1; Rvr; T3R[a]; T3Ralpha; Thra1; Thra2; TR alpha 1; TR alpha 2
Orthologs:
Homo sapiens (human) : THRA (thyroid hormone receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Thra (thyroid hormone receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thra (thyroid hormone receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : THRA (thyroid hormone receptor alpha)
Canis lupus familiaris (dog) : THRA (thyroid hormone receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thra (thyroid hormone receptor alpha)
Sus scrofa (pig) : THRA (thyroid hormone receptor alpha)
Chlorocebus sabaeus (African green monkey) : THRA (thyroid hormone receptor alpha)
Heterocephalus glaber (naked mole-rat) : Thra (thyroid hormone receptor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1198,740,638 - 98,769,006 (+)EnsemblGRCm38mm10GRCm38
GRCm381198,740,776 - 98,769,006 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371198,603,187 - 98,626,425 (+)NCBIGRCm37mm9NCBIm37
MGSCv361198,557,963 - 98,581,201 (+)NCBImm8
Celera11108,407,991 - 108,419,811 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Thra
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11415
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.