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Gene: Thra (thyroid hormone receptor alpha) Mus musculus
Symbol: Thra
Name: thyroid hormone receptor alpha
Description: Exhibits nuclear receptor activity and nucleic acid binding activity. Involved in several processes, including animal organ development; female mating behavior; and regulation of transcription, DNA-templated. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study thyroid hormone resistance syndrome. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 6 and renal cell carcinoma. Orthologous to human THRA (thyroid hormone receptor alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6430529J03Rik; AW259572; c-erbA-1; c-erbA-alpha; c-erbAalpha; Erba; Nr1a1; nuclear receptor subfamily 1 group A member 1; Rvr; T3R[a]; T3Ralpha; Thra1; Thra2; TR alpha 1; TR alpha 2
Homo sapiens (human) : THRA (thyroid hormone receptor alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Thra (thyroid hormone receptor alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thra (thyroid hormone receptor alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : THRA (thyroid hormone receptor alpha)
Canis lupus familiaris (dog) : THRA (thyroid hormone receptor alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thra (thyroid hormone receptor alpha)
Sus scrofa (pig) : THRA (thyroid hormone receptor alpha)
Chlorocebus sabaeus (African green monkey) : THRA (thyroid hormone receptor alpha)
Heterocephalus glaber (naked mole-rat) : Thra (thyroid hormone receptor alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1198,740,638 - 98,769,006 (+)EnsemblGRCm38mm10GRCm38
GRCm381198,740,776 - 98,769,006 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371198,603,187 - 98,626,425 (+)NCBIGRCm37mm9NCBIm37
MGSCv361198,557,963 - 98,581,201 (+)NCBImm8
Celera11108,407,991 - 108,419,811 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Thra
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11415
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.