Tnfrsf12a (tumor necrosis factor receptor superfamily, member 12a) - Rat Genome Database

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Gene: Tnfrsf12a (tumor necrosis factor receptor superfamily, member 12a) Mus musculus
Analyze
Symbol: Tnfrsf12a
Name: tumor necrosis factor receptor superfamily, member 12a
RGD ID: 1550230
MGI Page MGI
Description: Involved in regulation of angiogenesis. Acts upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Located in cell surface; plasma membrane; and ruffle. Is expressed in several structures, including adrenal medulla; alimentary system; genitourinary system; heart; and limb long bone. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI255180; C87282; FGF-inducible 14; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; fibroblast growth factor-regulated protein 2; Fn1; Fn14; HPIP; tumor necrosis factor receptor superfamily member 12A; Twea; TWEAK; TWEAK-R; tweak-receptor; TweakR; type I transmembrane protein Fn14
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,894,419 - 23,896,423 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,894,419 - 23,896,442 (-)EnsemblGRCm39 Ensembl
GRCm381723,675,445 - 23,677,449 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,675,445 - 23,677,468 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,812,412 - 23,814,416 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,403,067 - 23,405,066 (-)NCBIMGSCv36mm8
Celera1724,181,651 - 24,183,653 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1711.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-bromo-2'-deoxyuridine  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
arachidonic acid  (ISO)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
chloropicrin  (ISO)
choline  (EXP)
chromium(6+)  (EXP)
ciglitazone  (ISO)
cisplatin  (EXP,ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (EXP)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP,ISO)
diquat  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (ISO)
etoposide  (ISO)
fenamidone  (EXP)
fipronil  (ISO)
fluoranthene  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
iron dichloride  (ISO)
isoprenaline  (EXP)
L-methionine  (EXP)
leflunomide  (ISO)
Licochalcone B  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
mechlorethamine  (EXP)
melamine  (ISO)
menadione  (ISO)
mercury dichloride  (ISO)
metacetamol  (EXP)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalene  (EXP)
nickel atom  (ISO)
nickel sulfate  (EXP)
ochratoxin A  (ISO)
ofloxacin  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (ISO)
pentane-2,3-dione  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (ISO)
phenylephrine  (ISO)
phenylmercury acetate  (ISO)
phosgene  (EXP)
potassium chromate  (ISO)
progesterone  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
ranitidine  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
succimer  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
torcetrapib  (ISO)
triacsin C  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (IDA)
membrane  (IEA)
plasma membrane  (IBA,IDA)
ruffle  (IDA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Comparative analysis of apoptosis and inflammation genes of mice and humans. Reed JC, etal., Genome Res 2003 Jun;13(6B):1376-88.
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10551889   PMID:10751351   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11728344   PMID:12477932   PMID:12529173   PMID:12794080   PMID:12821115  
PMID:14573547   PMID:15489334   PMID:16110324   PMID:16141072   PMID:16141073   PMID:16424220   PMID:16526941   PMID:16602821   PMID:17003819   PMID:17015433   PMID:17124496   PMID:17383968  
PMID:17803219   PMID:17981048   PMID:18025243   PMID:18287559   PMID:19109961   PMID:19349318   PMID:19573558   PMID:20068578   PMID:20308426   PMID:20810696   PMID:20927042   PMID:20955770  
PMID:21040786   PMID:21267068   PMID:21873635   PMID:22081603   PMID:22394384   PMID:22982296   PMID:23325387   PMID:23342071   PMID:23462911   PMID:23497038   PMID:23576749   PMID:23578591  
PMID:23764551   PMID:23991053   PMID:23999007   PMID:24037740   PMID:24327607   PMID:24408972   PMID:24416188   PMID:24446436   PMID:24652288   PMID:24680686   PMID:24895120   PMID:25042397  
PMID:25504044   PMID:25524063   PMID:25826425   PMID:25911200   PMID:26192438   PMID:26808775   PMID:27305603   PMID:27634763   PMID:28428709   PMID:28530223   PMID:28562476   PMID:29588419  
PMID:29706927   PMID:29971943   PMID:29981796   PMID:30033152   PMID:30038329   PMID:30081003   PMID:30648117   PMID:30976982   PMID:31017010   PMID:31212034   PMID:31515807   PMID:31679818  
PMID:32217132   PMID:32542768   PMID:32670778   PMID:32979359   PMID:33526652   PMID:33578738   PMID:33755760   PMID:34155062   PMID:34646379   PMID:34797693   PMID:35902978   PMID:35907805  
PMID:36004645   PMID:36063885   PMID:36412933   PMID:36626628   PMID:37761958   PMID:37813488   PMID:38007933  


Genomics

Comparative Map Data
Tnfrsf12a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,894,419 - 23,896,423 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,894,419 - 23,896,442 (-)EnsemblGRCm39 Ensembl
GRCm381723,675,445 - 23,677,449 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,675,445 - 23,677,468 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,812,412 - 23,814,416 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,403,067 - 23,405,066 (-)NCBIMGSCv36mm8
Celera1724,181,651 - 24,183,653 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1711.99NCBI
TNFRSF12A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,020,368 - 3,022,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,018,445 - 3,022,383 (+)EnsemblGRCh38hg38GRCh38
GRCh37163,070,369 - 3,072,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,010,361 - 3,012,385 (+)NCBINCBI36Build 36hg18NCBI36
Build 34163,010,360 - 3,012,382NCBI
Celera163,275,870 - 3,277,940 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,042,784 - 3,043,958 (+)NCBIHuRef
CHM1_1163,070,187 - 3,072,258 (+)NCBICHM1_1
T2T-CHM13v2.0163,046,940 - 3,048,955 (+)NCBIT2T-CHM13v2.0
Tnfrsf12a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,211,670 - 13,213,666 (-)NCBIGRCr8
mRatBN7.21012,707,077 - 12,709,071 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,689,890 - 12,709,045 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,450,479 - 17,452,451 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,939,272 - 16,941,244 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,439,729 - 12,441,702 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,995,904 - 12,997,930 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,995,904 - 12,997,930 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,818,949 - 12,820,975 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41012,940,334 - 12,942,343 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11012,940,333 - 12,942,343 (-)NCBI
Celera1012,402,383 - 12,404,393 (-)NCBICelera
Cytogenetic Map10q12NCBI
Tnfrsf12a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,320,159 - 14,322,146 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,320,159 - 14,322,146 (-)NCBIChiLan1.0ChiLan1.0
TNFRSF12A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,565,122 - 3,567,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,343,507 - 7,345,554 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,962,179 - 1,964,223 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,134,577 - 3,136,581 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,134,577 - 3,136,581 (+)Ensemblpanpan1.1panPan2
TNFRSF12A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,166,160 - 38,168,189 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,166,160 - 38,168,189 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,406,703 - 39,408,732 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,476,762 - 38,478,791 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,476,762 - 38,478,906 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,162,557 - 38,164,586 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,135,059 - 38,137,088 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,610,821 - 38,612,857 (-)NCBIUU_Cfam_GSD_1.0
Tnfrsf12a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,558,357 - 105,560,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,149,076 - 1,151,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,149,169 - 1,151,098 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFRSF12A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,166,298 - 39,168,302 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,166,288 - 39,168,294 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,531,414 - 40,533,682 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFRSF12A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,763,633 - 2,765,692 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,763,714 - 2,765,137 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,066,705 - 28,068,765 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Tnfrsf12a
121 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:376
Count of miRNA genes:173
Interacting mature miRNAs:178
Transcripts:ENSMUST00000024698, ENSMUST00000167059
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1219832925076769Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171683545533819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
12910769Rtmq1_mrenal tumor modifier QTL 1 (mouse)172290003625721472Mouse

Markers in Region
C87282  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381723,675,524 - 23,675,639UniSTSGRCm38
MGSCv371723,812,491 - 23,812,606UniSTSGRCm37
Celera1724,181,730 - 24,181,845UniSTS
Cytogenetic Map17A3.3UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000024698   ⟹   ENSMUSP00000024698
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1723,894,419 - 23,896,442 (-)Ensembl
GRCm38.p6 Ensembl1723,675,445 - 23,677,468 (-)Ensembl
RefSeq Acc Id: ENSMUST00000167059   ⟹   ENSMUSP00000131574
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1723,894,619 - 23,896,403 (-)Ensembl
GRCm38.p6 Ensembl1723,675,645 - 23,677,429 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233040
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1723,894,683 - 23,895,527 (-)Ensembl
GRCm38.p6 Ensembl1723,675,709 - 23,676,553 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233428   ⟹   ENSMUSP00000156767
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1723,894,797 - 23,896,394 (-)Ensembl
GRCm38.p6 Ensembl1723,675,823 - 23,677,420 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233754
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1723,895,587 - 23,896,401 (-)Ensembl
GRCm38.p6 Ensembl1723,676,613 - 23,677,427 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233814   ⟹   ENSMUSP00000156786
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1723,894,467 - 23,896,401 (-)Ensembl
GRCm38.p6 Ensembl1723,675,493 - 23,677,427 (-)Ensembl
RefSeq Acc Id: NM_001161746   ⟹   NP_001155218
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391723,894,419 - 23,896,423 (-)NCBI
GRCm381723,675,445 - 23,677,449 (-)ENTREZGENE
MGSCv371723,812,412 - 23,814,416 (-)RGD
Celera1724,181,651 - 24,183,653 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_013749   ⟹   NP_038777
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391723,894,419 - 23,896,423 (-)NCBI
GRCm381723,675,445 - 23,677,449 (-)ENTREZGENE
MGSCv371723,812,412 - 23,814,416 (-)RGD
Celera1724,181,651 - 24,183,653 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_038777   ⟸   NM_013749
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3TVG8 (UniProtKB/Swiss-Prot),   Q9QZW3 (UniProtKB/Swiss-Prot),   Q9CR75 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001155218   ⟸   NM_001161746
- Peptide Label: isoform 2
- UniProtKB: E9PZT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000156767   ⟸   ENSMUST00000233428
RefSeq Acc Id: ENSMUSP00000156786   ⟸   ENSMUST00000233814
RefSeq Acc Id: ENSMUSP00000131574   ⟸   ENSMUST00000167059
RefSeq Acc Id: ENSMUSP00000024698   ⟸   ENSMUST00000024698

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CR75-F1-model_v2 AlphaFold Q9CR75 1-129 view protein structure

Promoters
RGD ID:13674938
Promoter ID:EPDNEW_M21618
Type:initiation region
Name:Tnfrsf12a_1
Description:Mus musculus tumor necrosis factor receptor superfamily, member12a , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381723,677,445 - 23,677,505EPDNEW
RGD ID:6848694
Promoter ID:MM_TRO:4244
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:MTR005143.17.499.2
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361723,813,051 - 23,813,842 (-)MPROMDB
RGD ID:6828814
Promoter ID:MM_KWN:22440
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001161746,   UC008ASV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361723,814,206 - 23,814,706 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1351484 AgrOrtholog
Ensembl Genes ENSMUSG00000023905 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000024698 ENTREZGENE
  ENSMUST00000024698.10 UniProtKB/Swiss-Prot
  ENSMUST00000167059 ENTREZGENE
  ENSMUST00000167059.9 UniProtKB/TrEMBL
  ENSMUST00000233428.2 UniProtKB/TrEMBL
  ENSMUST00000233814.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.400.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TNFR_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:27279 UniProtKB/Swiss-Prot
MGD MGI:1351484 ENTREZGENE
NCBI Gene 27279 ENTREZGENE
PANTHER PTHR32037 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam stn_TNFRSF12A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tnfrsf12a PhenoGen
PRINTS TNFACTORR12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B2W475_MOUSE UniProtKB/TrEMBL
  A0A3B2W7Y2_MOUSE UniProtKB/TrEMBL
  E9PZT5 ENTREZGENE, UniProtKB/TrEMBL
  Q3TVG8 ENTREZGENE
  Q9CR75 ENTREZGENE
  Q9QZW3 ENTREZGENE
  TNR12_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3TVG8 UniProtKB/Swiss-Prot
  Q9QZW3 UniProtKB/Swiss-Prot