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Gene: Epha2 (Eph receptor A2) Mus musculus
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Symbol: Epha2
Name: Eph receptor A2
Description: Predicted to have transmembrane-ephrin receptor activity. Involved in several processes, including animal organ development; blood vessel morphogenesis; and negative regulation of vasculature development. Localizes to the cell surface. Used to study cataract 6 multiple types. Human ortholog(s) of this gene implicated in cataract 6 multiple types. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; endometrium; and limb. Orthologous to human EPHA2 (EPH receptor A2); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW545284; Eck; ephrin type-A receptor 2; epithelial cell kinase; Myk2; Sek-2; Sek2; tyrosine-protein kinase receptor ECK; tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
Orthologs:
Homo sapiens (human) : EPHA2 (EPH receptor A2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Epha2 (Eph receptor A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epha2 (EPH receptor A2)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHA2 (EPH receptor A2)
Canis lupus familiaris (dog) : EPHA2 (EPH receptor A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epha2 (EPH receptor A2)
Sus scrofa (pig) : EPHA2 (EPH receptor A2)
Chlorocebus sabaeus (African green monkey) : EPHA2 (EPH receptor A2)
Heterocephalus glaber (naked mole-rat) : Epha2 (EPH receptor A2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl4141,301,240 - 141,329,384 (+)Ensembl
GRCm384141,301,221 - 141,329,384 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374140,857,155 - 140,885,293 (+)NCBIGRCm37mm9NCBIm37
MGSCv364140,573,316 - 140,601,454 (+)NCBImm8
Celera4143,116,853 - 143,145,205 (+)NCBICelera
Cytogenetic Map4 D3NCBI
cM Map473.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Epha2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316259
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.