Epha2 (Eph receptor A2) - Rat Genome Database

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Gene: Epha2 (Eph receptor A2) Mus musculus
Analyze
Symbol: Epha2
Name: Eph receptor A2
RGD ID: 1316259
MGI Page MGI
Description: Predicted to enable growth factor binding activity and transmembrane-ephrin receptor activity. Involved in several processes, including animal organ development; osteoblast differentiation; and regulation of blood vessel endothelial cell migration. Acts upstream of or within several processes, including blood vessel morphogenesis; nervous system development; and notochord development. Located in cell surface. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; endometrium; and limb. Used to study cataract 6 multiple types. Human ortholog(s) of this gene implicated in cataract 6 multiple types. Orthologous to human EPHA2 (EPH receptor A2); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW545284; Eck; ephrin type-A receptor 2; epithelial cell kinase; Myk2; Sek; Sek-; Sek-2; Sek2; tyrosine-protein kinase receptor ECK; tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,028,532 - 141,056,695 (+)NCBIGRCm39mm39
GRCm39 Ensembl4141,028,551 - 141,056,695 (+)Ensembl
GRCm384141,301,221 - 141,329,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,301,240 - 141,329,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,857,155 - 140,885,293 (+)NCBIGRCm37mm9NCBIm37
MGSCv364140,573,316 - 140,601,454 (+)NCBImm8
Celera4143,116,872 - 143,145,199 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
antimonite  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cholanic acid  (ISO)
cocaine  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cyproconazole  (EXP)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP,ISO)
dioxygen  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
doxazosin  (EXP)
doxorubicin  (ISO)
entinostat  (ISO)
fenamidone  (EXP)
fluoranthene  (EXP)
folic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
indole-3-methanol  (ISO)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lithocholic acid  (EXP,ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
metacetamol  (EXP)
methapyrilene  (ISO)
methotrexate  (EXP)
methylmercury chloride  (EXP,ISO)
mitomycin C  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel subsulfide  (ISO)
orphenadrine  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phosgene  (EXP)
pirinixic acid  (EXP)
ponatinib  (ISO)
propanal  (ISO)
quercetin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
temozolomide  (ISO)
Testosterone propionate  (EXP)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
triadimefon  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of GTPase activity  (ISO)
angiogenesis  (IEA)
apoptotic process  (IEA)
axial mesoderm formation  (IMP)
axon guidance  (IBA)
blood vessel development  (IMP)
blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (IMP)
blood vessel morphogenesis  (IMP)
bone remodeling  (IMP)
branching involved in mammary gland duct morphogenesis  (IMP)
cAMP metabolic process  (ISO)
cell adhesion  (IEA)
cell chemotaxis  (ISO)
cell differentiation  (IEA)
cell migration  (ISO)
cell motility  (ISO)
defense response to Gram-positive bacterium  (IMP)
ephrin receptor signaling pathway  (IDA,IMP,ISO)
inflammatory response  (IMP)
intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
keratinocyte differentiation  (ISO)
lens fiber cell morphogenesis  (IDA)
mammary gland epithelial cell proliferation  (IMP)
negative regulation of angiogenesis  (IMP)
negative regulation of chemokine production  (IMP)
negative regulation of cytokine production  (IMP)
negative regulation of lymphangiogenesis  (IMP)
negative regulation of protein kinase B signaling  (ISO)
neural tube development  (IMP)
neuron differentiation  (IDA,IMP)
notochord cell development  (IMP)
notochord formation  (IGI,IMP)
notochord morphogenesis  (IMP)
osteoblast differentiation  (IMP)
osteoclast differentiation  (IDA)
peptidyl-tyrosine phosphorylation  (IBA)
pericyte cell differentiation  (IMP)
phosphorylation  (IEA)
positive regulation of bicellular tight junction assembly  (ISO)
positive regulation of kinase activity  (IBA)
positive regulation of protein localization to plasma membrane  (ISO)
post-anal tail morphogenesis  (IMP)
protein kinase B signaling  (ISO)
protein localization to plasma membrane  (ISO)
protein phosphorylation  (IEA)
regulation of angiogenesis  (IDA)
regulation of blood vessel endothelial cell migration  (IDA)
regulation of cell adhesion mediated by integrin  (ISO)
regulation of ERK1 and ERK2 cascade  (ISO)
regulation of lamellipodium assembly  (ISO)
response to growth factor  (ISO)
skeletal system development  (IMP)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
vasculogenesis  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1281307   PMID:1295734   PMID:2174105   PMID:7511603   PMID:7543898   PMID:7609620   PMID:7890684   PMID:7893599   PMID:7918100   PMID:7947319   PMID:7982920   PMID:8108143  
PMID:8152808   PMID:8183555   PMID:8405064   PMID:8552593   PMID:8649815   PMID:8755474   PMID:8889548   PMID:8891343   PMID:8967950   PMID:9119409   PMID:9256343   PMID:9267020  
PMID:9463349   PMID:10323857   PMID:10349636   PMID:10415345   PMID:10495276   PMID:10654602   PMID:10725232   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11114734   PMID:11157778  
PMID:11217851   PMID:11222144   PMID:11287184   PMID:11403717   PMID:11423996   PMID:11431694   PMID:11439183   PMID:11567058   PMID:11978390   PMID:12217323   PMID:12466851   PMID:12477932  
PMID:12520002   PMID:12528186   PMID:12684176   PMID:12702665   PMID:12904583   PMID:14610273   PMID:14660441   PMID:14988728   PMID:15054110   PMID:15145949   PMID:15254900   PMID:15517401  
PMID:15872003   PMID:16141072   PMID:16141073   PMID:16166198   PMID:16208538   PMID:16446123   PMID:16481423   PMID:16547242   PMID:16602821   PMID:16782872   PMID:16849550   PMID:16977320  
PMID:17039519   PMID:17304517   PMID:17576135   PMID:17673999   PMID:17967808   PMID:18079969   PMID:18387945   PMID:18799693   PMID:18948590   PMID:19089910   PMID:19244130   PMID:19247962  
PMID:19299512   PMID:19321667   PMID:19426113   PMID:19443703   PMID:19542359   PMID:19649315   PMID:19769959   PMID:20100865   PMID:20112066   PMID:21135133   PMID:21267068   PMID:21344481  
PMID:21436445   PMID:21465626   PMID:21559471   PMID:21565611   PMID:21677750   PMID:21799118   PMID:21873635   PMID:22140528   PMID:22167091   PMID:22247486   PMID:22552283   PMID:22635007  
PMID:23308246   PMID:23401654   PMID:23686306   PMID:23906066   PMID:24026120   PMID:24550361   PMID:24561077   PMID:24713656   PMID:24795639   PMID:24952961   PMID:25073978   PMID:25166508  
PMID:25480914   PMID:25504371   PMID:26083390   PMID:26542681   PMID:26559065   PMID:26612952   PMID:26644518   PMID:26666565   PMID:26744526   PMID:26792178   PMID:26906157   PMID:26941654  
PMID:27401248   PMID:27549114   PMID:27665280   PMID:27733379   PMID:28294115   PMID:28338017   PMID:28390777   PMID:28552735   PMID:28581527   PMID:28743499   PMID:29216437   PMID:29582409  
PMID:29749928   PMID:29800803   PMID:29901151   PMID:30024304   PMID:30254164   PMID:31162144   PMID:31291578   PMID:31403678   PMID:31999807   PMID:32165640   PMID:32352641  


Genomics

Comparative Map Data
Epha2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,028,532 - 141,056,695 (+)NCBIGRCm39mm39
GRCm39 Ensembl4141,028,551 - 141,056,695 (+)Ensembl
GRCm384141,301,221 - 141,329,384 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,301,240 - 141,329,384 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,857,155 - 140,885,293 (+)NCBIGRCm37mm9NCBIm37
MGSCv364140,573,316 - 140,601,454 (+)NCBImm8
Celera4143,116,872 - 143,145,199 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.67NCBI
EPHA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl116,124,337 - 16,156,069 (-)EnsemblGRCh38hg38GRCh38
GRCh38116,124,337 - 16,156,104 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37116,450,832 - 16,482,564 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,323,419 - 16,355,151 (-)NCBINCBI36hg18NCBI36
Build 34116,196,138 - 16,227,870NCBI
Celera114,930,817 - 14,962,560 (-)NCBI
Cytogenetic Map1p36.13NCBI
HuRef114,968,749 - 15,000,153 (-)NCBIHuRef
CHM1_1116,249,454 - 16,281,203 (-)NCBICHM1_1
Epha2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25153,605,644 - 153,634,115 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl5153,605,644 - 153,634,117 (+)Ensembl
Rnor_6.05159,845,773 - 159,874,203 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,845,774 - 159,874,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,558,669 - 163,586,206 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,185,143 - 160,214,727 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15160,190,327 - 160,224,048 (+)NCBI
Celera5151,971,932 - 152,000,092 (+)NCBICelera
Cytogenetic Map5q36NCBI
Epha2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,120,266 - 2,152,781 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555272,120,447 - 2,151,932 (+)NCBIChiLan1.0ChiLan1.0
EPHA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1116,253,509 - 16,284,787 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,253,513 - 16,284,787 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0115,259,915 - 15,292,983 (-)NCBIMhudiblu_PPA_v0panPan3
EPHA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,534,130 - 81,561,722 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,534,125 - 81,561,725 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,070,108 - 78,097,636 (+)NCBI
ROS_Cfam_1.0282,179,960 - 82,207,481 (+)NCBI
UMICH_Zoey_3.1278,933,025 - 78,960,551 (+)NCBI
UNSW_CanFamBas_1.0279,950,185 - 79,977,704 (+)NCBI
UU_Cfam_GSD_1.0281,018,093 - 81,045,632 (+)NCBI
Epha2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,823,596 - 37,849,129 (-)NCBI
SpeTri2.0NW_0049364743,648,395 - 3,673,856 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,251,467 - 75,279,314 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,251,465 - 75,279,364 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,567,147 - 69,595,017 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPHA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,147,077 - 116,178,647 (+)NCBI
ChlSab1.1 Ensembl20116,147,040 - 116,178,644 (+)Ensembl
Vero_WHO_p1.0NW_02366605419,643,306 - 19,675,426 (+)NCBI
Epha2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247642,265,114 - 2,296,032 (-)NCBI

Position Markers
AW545284  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384141,328,870 - 141,329,001UniSTSGRCm38
MGSCv374140,884,785 - 140,884,916UniSTSGRCm37
Celera4143,144,691 - 143,144,822UniSTS
Cytogenetic Map4D-EUniSTS
Whitehead/MRC_RH41861.56UniSTS
Epha2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384141,328,535 - 141,329,255UniSTSGRCm38
MGSCv374140,884,450 - 140,885,170UniSTSGRCm37
Celera4143,144,356 - 143,145,076UniSTS
Cytogenetic Map4D-EUniSTS
cM Map473.2UniSTS
X78339  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384141,328,615 - 141,328,799UniSTSGRCm38
MGSCv374140,884,530 - 140,884,714UniSTSGRCm37
Celera4143,144,436 - 143,144,620UniSTS
Cytogenetic Map4D-EUniSTS
Whitehead_YAC4 UniSTS
Epha2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D-EUniSTS
Epha2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384141,328,504 - 141,329,070UniSTSGRCm38
MGSCv374140,884,419 - 140,884,985UniSTSGRCm37
Celera4143,144,325 - 143,144,891UniSTS
Cytogenetic Map4D-EUniSTS
Epha2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D-EUniSTS
cM Map473.2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465800000146500000Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468100000150800000Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined489063832151570093Mouse
13208562Wght7_mweight 7 (mouse)491000000148000000Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined495069342150592401Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105978113141706527Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105978113141706527Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105978113141706527Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105978113141706527Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107371164141371360Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107371164141371360Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107371164141371360Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107897771141897963Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108583899142583899Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108583899142583899Mouse
10755521Hct1_mhematocrit 1 (mouse)4108583899142583899Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111115258145115487Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111115258145115487Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112288593146288593Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112629696146629696Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112930596146930596Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116427367150427471Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117673830151673964Mouse
14746982Manh56_mmandible shape 56 (mouse)4118088606152088606Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4120137122154137225Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4120137122154137225Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120890537154890684Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120890537154890684Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120946694154946840Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120946694154946840Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121615338155615442Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121615338155615442Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121615338155615442Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4124100000144600000Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124161300141845481Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124161300142711450Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124371164142504390Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124371164150592401Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124826172156508116Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124893970156508116Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124893970156508116Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124893970156508116Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125504302156508116Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125504302156508116Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125504302156508116Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125562755156508116Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4128057656156508116Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4128057656156508116Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129572018151570093Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4132926037156508116Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133427367150704994Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133592276156508116Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134569994156508116Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134569994156508116Mouse
1357534Cinda3_mcytokine induced activation 3 (mouse)Not determined4137890537142562902Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137890537151570093Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137946694150592401Mouse
1300780Cocrb16_mcocaine related behavior 16 (mouse)Not determined4138859268156508116Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir26bmmu-miR-26b-5pOncomiRDBexternal_infoNANA21264258

Predicted Target Of
Summary Value
Count of predictions:872
Count of miRNA genes:555
Interacting mature miRNAs:657
Transcripts:ENSMUST00000006614, ENSMUST00000131026, ENSMUST00000145523, ENSMUST00000149002
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006538528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA237584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK144202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL607087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL670285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW457468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB817901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC140960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY024029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ088701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X76010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000006614   ⟹   ENSMUSP00000006614
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4141,028,551 - 141,056,695 (+)Ensembl
GRCm38.p6 Ensembl4141,301,240 - 141,329,384 (+)Ensembl
RefSeq Acc Id: ENSMUST00000131026
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4141,029,718 - 141,036,045 (+)Ensembl
GRCm38.p6 Ensembl4141,302,407 - 141,308,734 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145523
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4141,036,205 - 141,038,269 (+)Ensembl
GRCm38.p6 Ensembl4141,308,894 - 141,310,958 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149002
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4141,044,224 - 141,048,212 (+)Ensembl
GRCm38.p6 Ensembl4141,316,913 - 141,320,901 (+)Ensembl
RefSeq Acc Id: NM_010139   ⟹   NP_034269
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394141,028,532 - 141,056,695 (+)NCBI
GRCm384141,301,221 - 141,329,384 (+)ENTREZGENE
MGSCv374140,857,155 - 140,885,293 (+)RGD
Celera4143,116,853 - 143,145,205 (+)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006538528   ⟹   XP_006538591
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394141,038,043 - 141,056,695 (+)NCBI
GRCm384141,310,723 - 141,329,384 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163648   ⟹   XP_036019541
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394141,028,536 - 141,056,695 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_034269   ⟸   NM_010139
- Peptide Label: precursor
- UniProtKB: Q03145 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006538591   ⟸   XM_006538528
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000006614   ⟸   ENSMUST00000006614
RefSeq Acc Id: XP_036019541   ⟸   XM_036163648
- Peptide Label: isoform X1
Protein Domains
Eph LBD   Fibronectin type-III   Protein kinase   SAM

Promoters
RGD ID:6835264
Promoter ID:MM_KWN:40470
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000023711
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,856,946 - 140,857,446 (+)MPROMDB
RGD ID:6835265
Promoter ID:MM_KWN:40471
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung,   MEF_B4
Transcripts:OTTMUST00000023712
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,858,016 - 140,858,712 (+)MPROMDB
RGD ID:6849163
Promoter ID:MM_XEF:5220
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Lung
Transcripts:NM_001006764,   NM_001040678,   NM_001087611,   NM_001136173
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,862,279 - 140,862,779 (+)MPROMDB
RGD ID:6835269
Promoter ID:MM_KWN:40472
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000023713
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,864,211 - 140,864,812 (+)MPROMDB
RGD ID:6835271
Promoter ID:MM_KWN:40473
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung
Transcripts:OTTMUST00000023714
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364140,871,961 - 140,873,012 (+)MPROMDB
RGD ID:6885300
Promoter ID:EPDNEW_M6101
Type:multiple initiation site
Name:Epha2_1
Description:Mus musculus Eph receptor A2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384141,301,240 - 141,301,300EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95278 AgrOrtholog
Ensembl Genes ENSMUSG00000006445 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000006614 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000006614 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  2.60.120.260 UniProtKB/Swiss-Prot
  2.60.40.10 UniProtKB/Swiss-Prot
InterPro Eph_TM UniProtKB/Swiss-Prot
  EphA2_rcpt_lig-bd UniProtKB/Swiss-Prot
  Ephrin_rcpt_lig-bd_dom UniProtKB/Swiss-Prot
  FN3_dom UniProtKB/Swiss-Prot
  FN3_sf UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_ephrin_rcpt UniProtKB/Swiss-Prot
  Tyr_kinase_rcpt_V_CS UniProtKB/Swiss-Prot
KEGG Report mmu:13836 UniProtKB/Swiss-Prot
MGD MGI:95278 ENTREZGENE
NCBI Gene 13836 ENTREZGENE
Pfam EphA2_TM UniProtKB/Swiss-Prot
  Ephrin_lbd UniProtKB/Swiss-Prot
  fn3 UniProtKB/Swiss-Prot
  Pkinase_Tyr UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
PhenoGen Epha2 PhenoGen
PIRSF TyrPK_ephrin_receptor UniProtKB/Swiss-Prot
PRINTS TYRKINASE UniProtKB/Swiss-Prot
PROSITE EGF_2 UniProtKB/Swiss-Prot
  EPH_LBD UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_1 UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_V_2 UniProtKB/Swiss-Prot
  SAM_DOMAIN UniProtKB/Swiss-Prot
SMART EPH_lbd UniProtKB/Swiss-Prot
  FN3 UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
  SSF49265 UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot
  SSF57184 UniProtKB/Swiss-Prot
UniProt EPHA2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3UNI2 UniProtKB/Swiss-Prot
  Q60633 UniProtKB/Swiss-Prot
  Q62212 UniProtKB/Swiss-Prot