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Gene: Cdh3 (cadherin 3) Mus musculus
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Symbol: Cdh3
Name: cadherin 3
Description: This gene encodes a calcium-dependent cell-cell adhesion protein containing five cadherin domains. The encoded protein plays a role in epithelial outgrowth, such as that which occurs during the development of hair follicles and limb buds. Loss of function of the related gene in humans results in ectodermal dysplasia, ectrodactyly, and macular dystrophy and congential hypotrichosis with juvenile macular dystrophy. This gene is located in the vicinity of similar cadherin genes on chromosome 8. The proprotein is further cleaved into a functional chain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI385538; cadherin-3; Cadp; Cdhp; P-cadherin; Pcad; placental cadherin; RPE-specific cadherin
Orthologs:
Homo sapiens (human) : CDH3 (cadherin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdh3 (cadherin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdh3 (cadherin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : CDH3 (cadherin 3)
Canis lupus familiaris (dog) : CDH3 (cadherin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdh3 (cadherin 3)
Sus scrofa (pig) : CDH3 (cadherin 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm388106,510,852 - 106,556,911 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv378109,034,791 - 109,080,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv368109,400,020 - 109,446,037 (+)NCBImm8
Celera8110,734,906 - 110,781,301 (+)NCBICelera
Cytogenetic Map8 D3NCBI
cM Map853.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cdh3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1617635
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.