F5 (coagulation factor V) - Rat Genome Database

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Gene: F5 (coagulation factor V) Mus musculus
Analyze
Symbol: F5
Name: coagulation factor V
RGD ID: 10557
MGI Page MGI
Description: Predicted to have copper ion binding activity. Involved in blood circulation and blood coagulation. Localizes to extracellular space and platelet alpha granule. Is expressed in embryo; liver; liver left lobe; liver right lobe; and notochord. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); end stage renal disease; factor V deficiency; liver disease (multiple); and non-arteritic anterior ischemic optic neuropathy. Orthologous to human F5 (coagulation factor V).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activated protein C cofactor; AI173222; Cf-5; Cf5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,979,404 - 164,047,846 (+)NCBIGRCm39mm39
GRCm39 Ensembl1163,979,407 - 164,047,846 (+)Ensembl
GRCm381164,151,835 - 164,220,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,151,838 - 164,220,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv371166,081,990 - 166,150,405 (+)NCBIGRCm37mm9NCBIm37
MGSCv361165,988,633 - 166,056,215 (+)NCBImm8
Celera1166,589,960 - 166,658,650 (+)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
1q24 Deletion Syndrome  (ISO)
Acute Liver Failure  (ISO)
Behcet's disease  (ISO)
blood coagulation disease  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
Budd-Chiari syndrome  (ISO)
cerebral infarction  (ISO)
Colonic Neoplasms  (ISO)
colorectal adenoma  (ISO)
COVID-19  (ISO)
Dysarthria  (ISO)
Dyspnea  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Experimental Liver Cirrhosis  (ISO)
factor V deficiency  (ISO)
familial adenomatous polyposis  (ISO)
Femur Head Necrosis  (ISO)
Fetal Death  (ISO)
gastrointestinal stromal tumor  (ISO)
Habitual Abortions  (ISO)
hemorrhagic disease  (ISO)
hepatitis  (IEP,ISO)
Hereditary Thrombophilia  (ISO)
Hirschsprung's disease  (ISO)
hypereosinophilic syndrome  (ISO)
liver cirrhosis  (ISO)
membranoproliferative glomerulonephritis  (ISO)
Mesenteric Ischemia  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
non-arteritic anterior ischemic optic neuropathy  (ISO)
parathyroid carcinoma  (ISO)
Peritoneal Fibrosis  (ISO)
portal hypertension  (IEP)
pre-eclampsia  (ISO)
prostate cancer  (ISO)
pulmonary embolism  (ISO)
pulmonary fibrosis  (IMP)
pulmonary hypertension  (ISO)
retinal artery occlusion  (ISO)
retinal vein occlusion  (ISO)
sagittal sinus thrombosis  (ISO)
sensorineural hearing loss  (ISO)
Sepsis  (ISO)
Septic Peritonitis  (IMP)
Spontaneous Abortions  (ISO)
Stroke  (ISO)
thrombocytopenia  (ISO)
Thromboembolism  (ISO)
thrombophilia due to activated protein C resistance  (ISO)
thrombophilia due to thrombin defect  (ISO)
thrombosis  (IMP,ISO)
Venous Thromboembolism  (ISO)
Venous Thrombosis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
acenocoumarol  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
antimony(0)  (ISO)
antirheumatic drug  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
aspalathin  (ISO)
atorvastatin calcium  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buta-1,3-diene  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
calcium dichloride  (ISO)
chloroprene  (ISO)
chromium atom  (ISO)
chrysene  (EXP)
clofibrate  (EXP,ISO)
clofibric acid  (ISO)
clomiphene  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (EXP)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
Ethyl icosapentate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
glycidol  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
levonorgestrel  (ISO)
lithium chloride  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methapyrilene  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
ochratoxin A  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
phenprocoumon  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
propanal  (ISO)
propiconazole  (EXP)
quinapril hydrochloride  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
tolcapone  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
warfarin  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
blood circulation  (IBA,IMP)
blood coagulation  (IBA,IDA,IMP,ISO)
hemostasis  (IEA)
response to vitamin K  (ISO)

Cellular Component

Molecular Function

References

References - curated
1. Akman B, etal., Transplant Proc. 2006 Mar;38(2):413-5.
2. Amalia PM, etal., Dig Dis Sci. 2007 Oct;52(10):2616-21. Epub 2007 Apr 12.
3. Arsene S, etal., Thromb Haemost. 2005 Jul;94(1):101-6.
4. Ben-Ari Z, etal., Am J Gastroenterol. 1999 Oct;94(10):2977-82. doi: 10.1111/j.1572-0241.1999.01446.x.
5. Benfield TL, etal., J Infect Dis. 2005 Nov 15;192(10):1851-7. Epub 2005 Oct 12.
6. Cadoni G, etal., Ann Otol Rhinol Laryngol. 2006 Mar;115(3):195-200.
7. Capaccio P, etal., Laryngoscope. 2007 Mar;117(3):547-51.
8. Castoldi E and Rosing J, Curr Opin Hematol. 2004 May;11(3):176-81.
9. Coen D, etal., Croat Med J. 2001 Aug;42(4):488-92.
10. Colak Y, etal., Eur J Gastroenterol Hepatol. 2006 Aug;18(8):917-20.
11. Cui J, etal., Blood. 2000 Dec 15;96(13):4222-6.
12. Duga S, etal., Int J Biochem Cell Biol. 2004 Aug;36(8):1393-9.
13. Ekmekci Y, etal., Nephrol Dial Transplant. 2006 Dec;21(12):3555-8. Epub 2006 Sep 12.
14. El Sebay HM, etal., J Gastroenterol Hepatol. 2016 Jan;31(1):235-40. doi: 10.1111/jgh.13066.
15. Emiroglu O, etal., J Cardiothorac Surg. 2011 Sep 28;6:120.
16. Engelmann MG, etal., Angiology. 2004 Mar-Apr;55(2):221-5.
17. Goforth RL, etal., Kidney Int. 2006 Aug;70(4):743-50. Epub 2006 Jun 7.
18. Gorur K, etal., Otol Neurotol. 2005 Jul;26(4):599-601.
19. Gowda MS, etal., J Thromb Thrombolysis. 2000 Jan;9(1):43-5.
20. Guan ZY, etal., Eur Rev Med Pharmacol Sci. 2018 May;22(9):2742-2750. doi: 10.26355/eurrev_201805_14971.
21. Gul A, etal., Br J Rheumatol. 1996 Nov;35(11):1178-80.
22. Haller MJ, etal., Pediatr Diabetes. 2006 Aug;7(4):229-31.
23. Hefler L, etal., J Soc Gynecol Investig. 2004 Jan;11(1):42-4.
24. Irish AB, etal., Transplantation. 1997 Aug 27;64(4):604-7.
25. Ivancic MM, etal., Cancer Prev Res (Phila). 2014 Nov;7(11):1160-9. doi: 10.1158/1940-6207.CAPR-14-0056. Epub 2014 Sep 8.
26. Ivancic MM, etal., Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8471-8480. doi: 10.1073/pnas.1813212116. Epub 2019 Apr 10.
27. Juul K, etal., Ann Intern Med. 2004 Mar 2;140(5):330-7.
28. Juul K, etal., Arch Intern Med. 2005 Sep 26;165(17):2032-6.
29. Kaiser R, etal., J Rheumatol. 2012 Aug;39(8):1603-10. Epub 2012 Jun 15.
30. Kalayci D, etal., Acta Ophthalmol Scand. 1999 Dec;77(6):622-4.
31. Kerschen E, etal., J Thromb Haemost. 2015 Jun;13(6):1073-80. doi: 10.1111/jth.12876. Epub 2015 Mar 31.
32. Klai S, etal., Blood Coagul Fibrinolysis. 2012 Jul;23(5):406-10.
33. Laudes IJ, etal., Am J Pathol. 2002 May;160(5):1867-75.
34. Liu N, etal., Am J Physiol Renal Physiol. 2004 Oct;287(4):F612-20. Epub 2004 Jun 1.
35. Ludemann P, etal., Stroke. 1998 Dec;29(12):2507-10.
36. Mahmoud AE, etal., Gut. 1997 Jun;40(6):798-800. doi: 10.1136/gut.40.6.798.
37. Mello G, etal., Hypertension. 2005 Dec;46(6):1270-4. Epub 2005 Oct 24.
38. MGD and Homologene mouse data transfer
39. MGD data from the GO Consortium
40. MGD IEA
41. Middendorf K, etal., Am Heart J. 2004 May;147(5):897-904.
42. Nagy V, etal., Acta Ophthalmol Scand. 2004 Apr;82(2):140-3.
43. Nobukata H, etal., Toxicol Lett. 1999 Jan 11;104(1-2):93-101.
44. Norris LA, Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):369-83.
45. OMIM Disease Annotation Pipeline
46. Ong K, etal., Thromb Haemost 2000 Dec;84(6):1023-30.
47. Pereira LM, etal., Gut. 1992 Jan;33(1):98-102. doi: 10.1136/gut.33.1.98.
48. Pipeline to import KEGG annotations from KEGG into RGD
49. Pipeline to import SMPDB annotations from SMPDB into RGD
50. Plompen EP, etal., J Hepatol. 2015 Dec;63(6):1459-65. doi: 10.1016/j.jhep.2015.07.026. Epub 2015 Jul 27.
51. RGD automated import pipeline
52. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
53. RGD automated import pipeline for gene-chemical interactions
54. Saito H, etal., Perit Dial Int. 2009 May-Jun;29(3):340-51.
55. Siguret V, etal., J Gerontol A Biol Sci Med Sci. 2015 Aug;70(8):977-81. doi: 10.1093/gerona/glu240. Epub 2015 Feb 9.
56. Silingardi M, etal., Arthritis Rheum. 2004 Apr 15;51(2):177-83.
57. Sinclair SB and Levy GA, Dig Dis Sci. 1991 Jun;36(6):791-800. doi: 10.1007/bf01311239.
58. Smith SA, etal., Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28.
59. Sundquist K, etal., Thromb Haemost. 2015 Nov 25;114(6):1156-64. doi: 10.1160/TH15-01-0031. Epub 2015 Aug 6.
60. Tinholt M, etal., BMC Cancer. 2014 Nov 19;14:845. doi: 10.1186/1471-2407-14-845.
61. Tripathi G, etal., Clin Appl Thromb Hemost. 2010 Apr;16(2):132-40. Epub 2009 Jun 10.
62. Valla D, etal., Hepatology. 1989 Oct;10(4):482-7.
63. van Wijk R, etal., Br J Haematol. 2001 Sep;114(4):871-4.
64. Verity DH, etal., Am J Ophthalmol. 1999 Sep;128(3):352-6.
65. Weger M, etal., Eye. 2003 Aug;17(6):731-4.
66. Weischer M, etal., Atherosclerosis. 2010 Feb;208(2):480-3. Epub 2009 May 21.
67. Wong CL, etal., Blood Coagul Fibrinolysis. 2010 Apr;21(3):201-6.
68. Xu Z, etal., Thromb Haemost. 2001 Mar;85(3):441-4.
69. Yamaguchi K, etal., Shock. 2000 Nov;14(5):535-43.
70. Yasue M, etal., Cytogenet Cell Genet 1991;57(2-3):142-8
71. Zou ZS, etal., Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2003 Sep;17(3):274-6.
Additional References at PubMed
PMID:1694218   PMID:1889815   PMID:3175767   PMID:8288230   PMID:8900278   PMID:9616155   PMID:10349636   PMID:10669158   PMID:10829076   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:11533492   PMID:12466851   PMID:12816857   PMID:12855561   PMID:15452129   PMID:15569834   PMID:15809370   PMID:16141072   PMID:16141073   PMID:16359510   PMID:16514103   PMID:17438064  
PMID:17635646   PMID:17849058   PMID:17938812   PMID:18344422   PMID:19036061   PMID:19056689   PMID:19349621   PMID:19546589   PMID:19671356   PMID:19687358   PMID:20413539   PMID:20533258  
PMID:21267068   PMID:21389321   PMID:21677750   PMID:21795745   PMID:21873635   PMID:22008794   PMID:23216621   PMID:23325830   PMID:26075897   PMID:26251307   PMID:26341257   PMID:27237401  
PMID:28673898   PMID:28827327   PMID:28927238   PMID:30188893   PMID:31040226   PMID:31048328   PMID:32325033   PMID:32735640  


Genomics

Comparative Map Data
F5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,979,404 - 164,047,846 (+)NCBIGRCm39mm39
GRCm39 Ensembl1163,979,407 - 164,047,846 (+)Ensembl
GRCm381164,151,835 - 164,220,277 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,151,838 - 164,220,277 (+)EnsemblGRCm38mm10GRCm38
MGSCv371166,081,990 - 166,150,405 (+)NCBIGRCm37mm9NCBIm37
MGSCv361165,988,633 - 166,056,215 (+)NCBImm8
Celera1166,589,960 - 166,658,650 (+)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.46NCBI
F5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1169,511,951 - 169,586,588 (-)EnsemblGRCh38hg38GRCh38
GRCh381169,511,951 - 169,586,630 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371169,481,189 - 169,555,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,747,816 - 167,822,393 (-)NCBINCBI36hg18NCBI36
Build 341166,215,066 - 166,287,379NCBI
Celera1142,590,970 - 142,665,548 (-)NCBI
Cytogenetic Map1q24.2NCBI
HuRef1140,703,881 - 140,778,453 (-)NCBIHuRef
CHM1_11170,903,222 - 170,977,927 (-)NCBICHM1_1
F5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21376,513,463 - 76,583,106 (+)NCBI
Rnor_6.0 Ensembl1382,479,998 - 82,535,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01382,479,997 - 82,535,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01387,355,980 - 87,417,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41379,934,956 - 79,997,285 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1376,256,969 - 76,316,731 (+)NCBICelera
Cytogenetic Map13q23NCBI
F5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554627,694,939 - 7,757,463 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554627,695,004 - 7,757,832 (+)NCBIChiLan1.0ChiLan1.0
F5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11148,718,748 - 148,791,049 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1148,718,897 - 148,790,915 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01144,996,757 - 145,070,046 (-)NCBIMhudiblu_PPA_v0panPan3
F5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1728,999,481 - 29,069,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl728,999,512 - 29,069,296 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha728,531,164 - 28,601,084 (+)NCBI
ROS_Cfam_1.0728,801,509 - 28,871,406 (+)NCBI
UMICH_Zoey_3.1728,649,506 - 28,719,863 (+)NCBI
UNSW_CanFamBas_1.0728,685,240 - 28,755,563 (+)NCBI
UU_Cfam_GSD_1.0728,922,027 - 28,992,360 (+)NCBI
F5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934499,267,628 - 99,332,463 (+)NCBI
SpeTri2.0NW_00493648117,114,441 - 17,178,902 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl481,403,232 - 81,485,055 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1481,403,273 - 81,484,908 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2489,027,936 - 89,109,573 (+)NCBISscrofa10.2Sscrofa10.2susScr3
F5
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12559,465,610 - 59,539,022 (+)NCBI
ChlSab1.1 Ensembl2559,466,378 - 59,538,872 (+)Ensembl
Vero_WHO_p1.0NW_02366605561,142,905 - 61,215,886 (+)NCBI
F5
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248267,438,632 - 7,507,322 (-)NCBI

Position Markers
AI173222  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381164,217,415 - 164,217,505UniSTSGRCm38
MGSCv371166,147,546 - 166,147,636UniSTSGRCm37
Celera1166,658,516 - 166,658,606UniSTS
Cytogenetic Map1H2.2UniSTS
Whitehead/MRC_RH12082.32UniSTS
F5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381164,184,923 - 164,185,051UniSTSGRCm38
MGSCv371166,115,054 - 166,115,182UniSTSGRCm37
Celera1166,623,125 - 166,623,253UniSTS
Cytogenetic Map1H2.2UniSTS
cM Map186.6UniSTS
PMC18721P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381164,185,332 - 164,185,732UniSTSGRCm38
MGSCv371166,115,463 - 166,115,863UniSTSGRCm37
Celera1166,623,519 - 166,623,919UniSTS
Cytogenetic Map1H2.2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131228571165311895Mouse
14746980Manh50_mmandible shape 50 (mouse)1134255813168255813Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135919071169919261Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1136002150170002264Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136334204170334348Mouse
1300837Vmbic1_mventral midbrain iron content 1 (mouse)Not determined1139624618173624738Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139624618173624738Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139774467173774646Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139774467173774646Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139774467173774646Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139774467173774646Mouse
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139774467173774646Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139774467173774646Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139774467173774646Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139774467173774646Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141267440175267586Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141405603175405702Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141405603175405702Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141405603175405702Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141405603175405702Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142661973176662164Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143457095177457233Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144621573178621573Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144703778178704023Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145250061179250061Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145317638179317756Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1147032461167758653Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147249520169211344Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147249520171804689Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147249520183092234Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147249520189251027Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147391821181391821Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147391821181391821Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9148047933182048047Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1148047933182048047Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150317922188627115Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150317922188627115Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150317922188627115Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150929168184929353Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151358674185358833Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined152007542186007711Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152211172186211344Mouse
4142119Bpq21_mblood pressure QTL 21 (mouse)Not determined1152211172186211344Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152211172186211344Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152211172186211344Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152211172186211344Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152211172186211344Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152305175186305175Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152305175186305175Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152919071186706423Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153681660175641372Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153848421187848536Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153885284187885284Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154582944188582944Mouse
1301164Tir3c_mtrypansomiasis infection response 3c (mouse)Not determined1154804480188804689Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155175373189175373Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155175373189175373Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155175373189175373Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155698056189699966Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155699229189699330Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155706491186261999Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155888654189888802Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155888654189888802Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155888654189888802Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155893961189895041Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined156004198190004325Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1156004198190004325Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1156004198190004325Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1156004198190004325Mouse
1301232Hcs7_mhepatocarcinogenesis susceptibility 7 (mouse)Not determined1156774467168358833Mouse
13452394Leusq1_mleucocytosis susceptibility QTL 1 (mouse)1156774467168358833Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156774467170976071Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156774467176435127Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156774467189571420Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156774467189571420Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157628733191628870Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157628733191628870Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157628733191628870Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157628733191628870Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157628733191628870Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157628733191628870Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157628733191628870Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1163149528186261999Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:179
Count of miRNA genes:148
Interacting mature miRNAs:165
Transcripts:ENSMUST00000086040
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000086040   ⟹   ENSMUSP00000083204
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1164,151,838 - 164,220,277 (+)Ensembl
RefSeq Acc Id: NM_007976   ⟹   NP_032002
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391163,979,404 - 164,047,846 (+)NCBI
GRCm381164,151,835 - 164,220,277 (+)NCBI
MGSCv371166,081,990 - 166,150,405 (+)RGD
Celera1166,589,960 - 166,658,650 (+)RGD
cM Map1 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032002   ⟸   NM_007976
- Peptide Label: preproprotein
- UniProtKB: O88783 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000083204   ⟸   ENSMUST00000086040
Protein Domains
F5/8 type A   F5/8 type C   Plastocyanin-like

Promoters
RGD ID:6875506
Promoter ID:EPDNEW_M1204
Type:initiation region
Name:F5_1
Description:Mus musculus coagulation factor V , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381164,151,827 - 164,151,887EPDNEW
RGD ID:6817697
Promoter ID:MM_KWN:2679
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:ENSMUST00000086040
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361166,081,646 - 166,082,146 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88382 AgrOrtholog
Ensembl Genes ENSMUSG00000026579 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000083204 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000086040 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.420 UniProtKB/Swiss-Prot
InterPro Cu-oxidase_3 UniProtKB/Swiss-Prot
  Cu_oxidase_CS UniProtKB/Swiss-Prot
  Cupredoxin UniProtKB/Swiss-Prot
  FA58C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Factor_5/8-like UniProtKB/Swiss-Prot
  Galactose-bd-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14067 UniProtKB/Swiss-Prot
MGD MGI:88382 ENTREZGENE
NCBI Gene 14067 ENTREZGENE
Pfam Cu-oxidase_3 UniProtKB/Swiss-Prot
  F5_F8_type_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB F5 RGD
PhenoGen F5 PhenoGen
PIRSF Factors_V_VIII UniProtKB/Swiss-Prot
PROSITE FA58C_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FA58C_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FA58C_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MULTICOPPER_OXIDASE1 UniProtKB/Swiss-Prot
SMART FA58C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49503 UniProtKB/Swiss-Prot
  SSF49785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FA5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C7H9_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3UTQ2 UniProtKB/Swiss-Prot
  Q3UV80 UniProtKB/Swiss-Prot