Ifnar1 (interferon (alpha and beta) receptor 1) - Rat Genome Database

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Gene: Ifnar1 (interferon (alpha and beta) receptor 1) Mus musculus
Analyze
Symbol: Ifnar1
Name: interferon (alpha and beta) receptor 1
RGD ID: 1313409
MGI Page MGI
Description: Exhibits type I interferon binding activity and type I interferon receptor activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of cytokine production; and response to lipopolysaccharide. Localizes to integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis C. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1); PARTICIPATES IN type I interferon signaling pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 4-hydroxyphenyl retinamide; carbon nanotube; clofibrate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD118; I; If; Ifar; IFN-alpha/beta receptor 1; IFN-alpha/betaR; IFN-R-1; Ifnar; Ifrc; INF-a receptor; Infar; interferon alpha/beta receptor 1; interferon-alpha/beta receptor 1; type I interferon receptor 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,281,016 - 91,307,411 (+)NCBIGRCm39mm39
GRCm39 Ensembl1691,282,126 - 91,304,329 (+)Ensembl
GRCm381691,485,032 - 91,510,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,485,238 - 91,507,441 (+)EnsemblGRCm38mm10GRCm38
MGSCv371691,485,460 - 91,510,768 (+)NCBIGRCm37mm9NCBIm37
MGSCv361691,374,108 - 91,396,296 (+)NCBImm8
Celera1692,562,831 - 92,587,086 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1652.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal blood homeostasis  (IAGP)
abnormal CD8-positive, alpha-beta T cell physiology  (IAGP)
abnormal cytokine level  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal gait  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal interferon-gamma secretion  (IAGP)
abnormal leukocyte migration  (IAGP)
abnormal lymphopoiesis  (IAGP)
abnormal macrophage morphology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal mononuclear phagocyte morphology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal NK cell physiology  (IAGP)
abnormal osteoclast morphology  (IAGP)
abnormal response to infection  (IAGP)
abnormal skin condition  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal susceptibility to infection  (IAGP)
abnormal vibrissa morphology  (IEA)
anemia  (IAGP)
astrocytosis  (IAGP)
brain inflammation  (IAGP)
corneal vascularization  (IAGP)
decreased anti-nuclear antigen antibody level  (IAGP)
decreased autoantibody level  (IAGP)
decreased bone mineral density  (IAGP)
decreased circulating fructosamine level  (IEA)
decreased fetal size  (IAGP)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG2a level  (IAGP)
decreased IgG3 level  (IAGP)
decreased IgM level  (IAGP)
decreased interferon-alpha secretion  (IAGP)
decreased interferon-beta secretion  (IAGP)
decreased interleukin-6 secretion  (IAGP)
decreased KLRG1-positive NK cell number  (IEA)
decreased Ly6C high monocyte number  (IAGP)
decreased mean platelet volume  (IEA)
decreased monocyte cell number  (IEA)
decreased NK cell number  (IAGP)
decreased susceptibility to Coronaviridae infection  (IAGP)
decreased susceptibility to Orthomyxoviridae infection  (IAGP)
decreased susceptibility to Orthomyxoviridae infection induced morbidity/mortality  (IAGP)
decreased susceptibility to systemic lupus erythematosus  (IAGP)
decreased T cell apoptosis  (IAGP)
decreased total body fat amount  (IEA)
decreased tumor necrosis factor secretion  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
glomerulonephritis  (IAGP)
impaired natural killer cell mediated cytotoxicity  (IAGP)
improved glucose tolerance  (IEA)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased bone mineral content  (IEA)
increased bone mineral density  (IEA)
increased CD4-positive, alpha beta T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased circulating alanine transaminase level  (IAGP)
increased circulating creatinine level  (IEA)
increased circulating interleukin-10 level  (IAGP)
increased circulating interleukin-12 level  (IAGP)
increased circulating interleukin-18 level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased IgA level  (IAGP)
increased IgG level  (IAGP)
increased IgG2b level  (IAGP)
increased IgG3 level  (IAGP)
increased IgM level  (IAGP)
increased incidence of induced tumors  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased lean body mass  (IEA)
increased leukocyte cell number  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen weight  (IAGP)
increased susceptibility to Adenoviridae infection  (IEA)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
increased susceptibility to Coronaviridae infection  (IAGP)
increased susceptibility to Coronaviridae infection induced morbidity/mortality  (IAGP)
increased susceptibility to Herpesvirales infection  (IAGP)
increased susceptibility to Herpesvirales infection induced morbidity/mortality  (IAGP)
increased susceptibility to Orthomyxoviridae infection  (IAGP)
increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality  (IAGP)
increased susceptibility to Paramyxoviridae infection  (IAGP)
increased susceptibility to Paramyxoviridae infection induced morbidity/mortality  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to parasitic infection induced morbidity/mortality  (IAGP)
increased susceptibility to Picornaviridae infection  (IAGP)
increased susceptibility to Picornaviridae infection induced morbidity/mortality  (IAGP)
increased susceptibility to Poxviridae infection  (IAGP)
increased susceptibility to Riboviria infection  (IAGP)
increased susceptibility to systemic lupus erythematosus  (IAGP)
increased susceptibility to Togaviridae infection  (IAGP)
increased susceptibility to Togaviridae infection induced morbidity/mortality  (IAGP)
increased tumor growth/size  (IAGP)
increased urine protein level  (IAGP)
induced hyperactivity  (IAGP)
joint inflammation  (IAGP)
lethargy  (IAGP)
liver hemorrhage  (IAGP)
lung hemorrhage  (IAGP)
lung inflammation  (IAGP)
meningitis  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
pulmonary hyperemia  (IAGP)
rheumatoid arthritis  (IAGP)
salivary gland inflammation  (IAGP)
small lymph nodes  (IAGP)
References

Additional References at PubMed
PMID:1380419   PMID:1533935   PMID:1783381   PMID:2144902   PMID:2153461   PMID:2513475   PMID:3160288   PMID:6154946   PMID:6155698   PMID:6184821   PMID:7479980   PMID:7609046  
PMID:7713924   PMID:7749229   PMID:7759999   PMID:7884863   PMID:7958966   PMID:8009221   PMID:8181059   PMID:8318737   PMID:8496154   PMID:8661709   PMID:8786318   PMID:8889548  
PMID:9104811   PMID:9110990   PMID:9175833   PMID:9244437   PMID:9414161   PMID:9419213   PMID:9525580   PMID:9621024   PMID:9687534   PMID:9696838   PMID:9802982   PMID:10069426  
PMID:10209048   PMID:10233935   PMID:10349636   PMID:10400797   PMID:10441734   PMID:10562320   PMID:10640742   PMID:10666256   PMID:10714556   PMID:10754318   PMID:10756011   PMID:10801979  
PMID:10875919   PMID:10982374   PMID:11034357   PMID:11042159   PMID:11076861   PMID:11114377   PMID:11119576   PMID:11163195   PMID:11217851   PMID:11264360   PMID:11310846   PMID:11369881  
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PMID:17312160   PMID:17339421   PMID:17339445   PMID:17360658   PMID:17372008   PMID:17372191   PMID:17389237   PMID:17398124   PMID:17426143   PMID:17431131   PMID:17452523   PMID:17475783  
PMID:17475855   PMID:17475892   PMID:17485512   PMID:17502662   PMID:17506816   PMID:17507470   PMID:17513714   PMID:17513722   PMID:17513736   PMID:17548519   PMID:17548588   PMID:17579073  
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PMID:18250457   PMID:18282093   PMID:18287559   PMID:18292236   PMID:18322196   PMID:18322213   PMID:18322221   PMID:18339305   PMID:18354186   PMID:18354215   PMID:18354236   PMID:18362156  
PMID:18368052   PMID:18382764   PMID:18390731   PMID:18412159   PMID:18424188   PMID:18453565   PMID:18480244   PMID:18482773   PMID:18490712   PMID:18490714   PMID:18495762   PMID:18535656  
PMID:18562532   PMID:18591384   PMID:18619869   PMID:18641299   PMID:18641348   PMID:18656388   PMID:18663004   PMID:18667505   PMID:18716002   PMID:18722370   PMID:18787692   PMID:18799577  
PMID:18802094   PMID:18824599   PMID:18845149   PMID:18937499   PMID:18978796   PMID:18979509   PMID:19006696   PMID:19009526   PMID:19039769   PMID:19074283   PMID:19118004   PMID:19121307  
PMID:19124753   PMID:19130558   PMID:19154989   PMID:19201883   PMID:19201884   PMID:19201901   PMID:19229247   PMID:19234173   PMID:19265146   PMID:19319188   PMID:19342641   PMID:19342665  
PMID:19357779   PMID:19380790   PMID:19384870   PMID:19406830   PMID:19414755   PMID:19483695   PMID:19494276   PMID:19540914   PMID:19544312   PMID:19553532   PMID:19576795   PMID:19581626  
PMID:19587008   PMID:19587448   PMID:19620292   PMID:19620305   PMID:19635913   PMID:19637226   PMID:19687227   PMID:19717517   PMID:19733096   PMID:19798431   PMID:19805514   PMID:19808647  
PMID:19812195   PMID:19828630   PMID:19850889   PMID:19864599   PMID:19877012   PMID:19877013   PMID:19901080   PMID:19933871   PMID:19939913   PMID:19948722   PMID:19949066   PMID:19960021  
PMID:20007534   PMID:20037154   PMID:20065291   PMID:20067542   PMID:20071504   PMID:20079668   PMID:20080755   PMID:20123960   PMID:20123961   PMID:20164263   PMID:20176744   PMID:20181884  
PMID:20200244   PMID:20200270   PMID:20221252   PMID:20360404   PMID:20386712   PMID:20395428   PMID:20400700   PMID:20422028   PMID:20427775   PMID:20436908   PMID:20457908   PMID:20465570  
PMID:20483775   PMID:20484025   PMID:20513754   PMID:20535209   PMID:20562259   PMID:20566717   PMID:20566831   PMID:20573823   PMID:20584765   PMID:20585572   PMID:20592088   PMID:20592282  
PMID:20605974   PMID:20610651   PMID:20637658   PMID:20637660   PMID:20660347   PMID:20661430   PMID:20674859   PMID:20699362   PMID:20706988   PMID:20713887   PMID:20720209   PMID:20736166  
PMID:20821729   PMID:20861272   PMID:20870934   PMID:20876348   PMID:20926559   PMID:20943997   PMID:20974942   PMID:20978541   PMID:21041726   PMID:21085181   PMID:21098219   PMID:21115688  
PMID:21147921   PMID:21160043   PMID:21178015   PMID:21255009   PMID:21266535   PMID:21267068   PMID:21282509   PMID:21333555   PMID:21349431   PMID:21365015   PMID:21379341   PMID:21383240  
PMID:21402764   PMID:21408089   PMID:21446050   PMID:21458307   PMID:21469086   PMID:21469099   PMID:21471447   PMID:21477795   PMID:21515676   PMID:21518880   PMID:21527253   PMID:21540188  
PMID:21592863   PMID:21606371   PMID:21622562   PMID:21674481   PMID:21677750   PMID:21690321   PMID:21695243   PMID:21712396   PMID:21746813   PMID:21757742   PMID:21788443   PMID:21804557  
PMID:21810605   PMID:21813451   PMID:21816907   PMID:21830209   PMID:21832166   PMID:21832278   PMID:21841308   PMID:21873635   PMID:21900395   PMID:21902795   PMID:21915277   PMID:21918184  
PMID:21931625   PMID:21937652   PMID:21949815   PMID:21963602   PMID:22022510   PMID:22036947   PMID:22042864   PMID:22044243   PMID:22048770   PMID:22072781   PMID:22114338   PMID:22130542  
PMID:22131327   PMID:22138643   PMID:22156349   PMID:22156592   PMID:22163016   PMID:22206014   PMID:22212606   PMID:22215738   PMID:22227568   PMID:22238311   PMID:22241991   PMID:22250092  
PMID:22251703   PMID:22284419   PMID:22308317   PMID:22308473   PMID:22315415   PMID:22327071   PMID:22379089   PMID:22396045   PMID:22412192   PMID:22419801   PMID:22422888   PMID:22474018  
PMID:22474394   PMID:22479645   PMID:22490865   PMID:22504642   PMID:22508860   PMID:22547696   PMID:22555457   PMID:22566567   PMID:22615570   PMID:22622426   PMID:22626807   PMID:22636319  
PMID:22672212   PMID:22706089   PMID:22711893   PMID:22719255   PMID:22761313   PMID:22786773   PMID:22792298   PMID:22802351   PMID:22815273   PMID:22815848   PMID:22821964   PMID:22840842  
PMID:22844479   PMID:22851707   PMID:22875973   PMID:22893686   PMID:22896628   PMID:22904308   PMID:22908290   PMID:22911155   PMID:22933295   PMID:22933629   PMID:22972924   PMID:22973027  
PMID:22980983   PMID:22982991   PMID:23023393   PMID:23071286   PMID:23100513   PMID:23125414   PMID:23129613   PMID:23170251   PMID:23175700   PMID:23213237   PMID:23236145   PMID:23260194  
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PMID:23554175   PMID:23580528   PMID:23585679   PMID:23610140   PMID:23623383   PMID:23653476   PMID:23656738   PMID:23659714   PMID:23737750   PMID:23770228   PMID:23771666   PMID:23772034  
PMID:23780878   PMID:23785507   PMID:23791647   PMID:23823318   PMID:23840314   PMID:23840854   PMID:23853595   PMID:23863621   PMID:23872679   PMID:23874199   PMID:23887873   PMID:23903655  
PMID:23903830   PMID:23911821   PMID:23913971   PMID:23935197   PMID:23960239   PMID:23972988   PMID:23975863   PMID:23976880   PMID:23980205   PMID:23986582   PMID:23990781   PMID:23991083  
PMID:23997220   PMID:24014876   PMID:24081947   PMID:24105635   PMID:24136200   PMID:24145511   PMID:24145513   PMID:24173228   PMID:24204252   PMID:24216477   PMID:24244159   PMID:24257618  
PMID:24262201   PMID:24278020   PMID:24284323   PMID:24304616   PMID:24307589   PMID:24307739   PMID:24334027   PMID:24335291   PMID:24335529   PMID:24353186   PMID:24362933   PMID:24367005  
PMID:24367096   PMID:24375615   PMID:24376264   PMID:24391507   PMID:24408967   PMID:24409099   PMID:24425713   PMID:24429359   PMID:24434209   PMID:24435166   PMID:24474779   PMID:24478444  
PMID:24480543   PMID:24489947   PMID:24493802   PMID:24498220   PMID:24523322   PMID:24530055   PMID:24531377   PMID:24532583   PMID:24555997   PMID:24574394   PMID:24574405   PMID:24589924  
PMID:24598055   PMID:24599590   PMID:24604832   PMID:24631156   PMID:24637670   PMID:24648449   PMID:24688025   PMID:24696235   PMID:24711580   PMID:24741106   PMID:24743949   PMID:24747678  
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PMID:25639361   PMID:25642773   PMID:25653430   PMID:25653440   PMID:25673724   PMID:25692705   PMID:25707806   PMID:25716322   PMID:25719445   PMID:25732191   PMID:25756182   PMID:25774715  
PMID:25774716   PMID:25795758   PMID:25843711   PMID:25849543   PMID:25855746   PMID:25885435   PMID:25896511   PMID:25900439   PMID:25901316   PMID:25902143   PMID:25911755   PMID:25918247  
PMID:25921537   PMID:25938762   PMID:25953241   PMID:25954804   PMID:25987506   PMID:26019270   PMID:26059829   PMID:26066745   PMID:26077719   PMID:26098211   PMID:26114879   PMID:26134179  
PMID:26212250   PMID:26232452   PMID:26241055   PMID:26263500   PMID:26292317   PMID:26320999   PMID:26407316   PMID:26451483   PMID:26457795   PMID:26461455   PMID:26468541   PMID:26484769  
PMID:26519535   PMID:26549455   PMID:26553503   PMID:26562011   PMID:26588782   PMID:26609155   PMID:26612263   PMID:26618925   PMID:26621722   PMID:26621862   PMID:26627716   PMID:26633895  
PMID:26634654   PMID:26670386   PMID:26682986   PMID:26755706   PMID:26787880   PMID:26811327   PMID:26824662   PMID:26867177   PMID:26912623   PMID:26912904   PMID:26918359   PMID:26928844  
PMID:26944200   PMID:26984726   PMID:26984727   PMID:26992431   PMID:27022155   PMID:27022620   PMID:27043411   PMID:27052162   PMID:27064756   PMID:27069113   PMID:27075414   PMID:27096319  
PMID:27128797   PMID:27129230   PMID:27137488   PMID:27149521   PMID:27149619   PMID:27151946   PMID:27152708   PMID:27158906   PMID:27160900   PMID:27170753   PMID:27170759   PMID:27180225  
PMID:27226090   PMID:27264175   PMID:27264176   PMID:27292635   PMID:27295349   PMID:27312374   PMID:27327515   PMID:27332732   PMID:27369778   PMID:27391363   PMID:27400725   PMID:27404846  
PMID:27440896   PMID:27459510   PMID:27477283   PMID:27533013   PMID:27565347   PMID:27610573   PMID:27612415   PMID:27621476   PMID:27622045   PMID:27647832   PMID:27653690   PMID:27663672  
PMID:27670299   PMID:27681121   PMID:27701741   PMID:27704310   PMID:27709605   PMID:27716507   PMID:27740718   PMID:27756058   PMID:27760315   PMID:27793594   PMID:27812214   PMID:27841872  
PMID:27872905   PMID:27884405   PMID:27912060   PMID:27917412   PMID:27927647   PMID:27974562   PMID:27974667   PMID:27980033   PMID:27995614   PMID:28009279   PMID:28018990   PMID:28087453  
PMID:28099860   PMID:28100675   PMID:28111081   PMID:28134626   PMID:28196594   PMID:28199846   PMID:28240606   PMID:28250124   PMID:28264970   PMID:28273457   PMID:28289093   PMID:28314593  
PMID:28340348   PMID:28356390   PMID:28362871   PMID:28373582   PMID:28380351   PMID:28396343   PMID:28400473   PMID:28415995   PMID:28416600   PMID:28424327   PMID:28436428   PMID:28439019  
PMID:28468974   PMID:28475892   PMID:28484023   PMID:28503979   PMID:28525755   PMID:28567448   PMID:28584007   PMID:28589934   PMID:28598415   PMID:28614719   PMID:28615418   PMID:28619948  
PMID:28622511   PMID:28630094   PMID:28634194   PMID:28636595   PMID:28636955   PMID:28637751   PMID:28647375   PMID:28659486   PMID:28678581   PMID:28708997   PMID:28716804   PMID:28723569  
PMID:28733313   PMID:28742068   PMID:28747383   PMID:28753426   PMID:28775298   PMID:28836263   PMID:28846084   PMID:28874687   PMID:28904198   PMID:28910635   PMID:28959042   PMID:28966054  
PMID:28978474   PMID:29030458   PMID:29055005   PMID:29055012   PMID:29070614   PMID:29117563   PMID:29117564   PMID:29127186   PMID:29176737   PMID:29190678   PMID:29203515   PMID:29203528  
PMID:29212904   PMID:29230002   PMID:29263859   PMID:29305462   PMID:29317641   PMID:29321274   PMID:29324904   PMID:29330321   PMID:29352265   PMID:29364865   PMID:29367469   PMID:29378173  
PMID:29436412   PMID:29445153   PMID:29459437   PMID:29507355   PMID:29531213   PMID:29558366   PMID:29562174   PMID:29576451   PMID:29588348   PMID:29590614   PMID:29632368   PMID:29651984  
PMID:29669251   PMID:29719256   PMID:29746837   PMID:29752314   PMID:29753791   PMID:29786074   PMID:29799838   PMID:29915078   PMID:29925850   PMID:29972777   PMID:29976926   PMID:29996101  
PMID:30002446   PMID:30004580   PMID:30018108   PMID:30021146   PMID:30063220   PMID:30067973   PMID:30084830   PMID:30111869   PMID:30131424   PMID:30134157   PMID:30143632   PMID:30199752  
PMID:30224374   PMID:30245008   PMID:30266768   PMID:30282022   PMID:30297531   PMID:30347820   PMID:30348900   PMID:30392829   PMID:30392830   PMID:30392956   PMID:30451651   PMID:30463976  
PMID:30473701   PMID:30511641   PMID:30517866   PMID:30523277   PMID:30540940   PMID:30573745   PMID:30575728   PMID:30587103   PMID:30587590   PMID:30591559   PMID:30595553   PMID:30680794  
PMID:30723095   PMID:30759384   PMID:30772497   PMID:30787296   PMID:30796216   PMID:30811982   PMID:30811989   PMID:30814285   PMID:30827680   PMID:30830879   PMID:30833347   PMID:30884311  
PMID:30886418   PMID:30890658   PMID:30902831   PMID:30917523   PMID:30944222   PMID:30988430   PMID:31024525   PMID:31053626   PMID:31097594   PMID:31103381   PMID:31130511   PMID:31141689  
PMID:31143178   PMID:31213650   PMID:31242184   PMID:31243154   PMID:31255879   PMID:31269444   PMID:31293597   PMID:31309159   PMID:31329638   PMID:31358656   PMID:31358982   PMID:31377243  
PMID:31385572   PMID:31434732   PMID:31477704   PMID:31519886   PMID:31548683   PMID:31577946   PMID:31611644   PMID:31619554   PMID:31619669   PMID:31619733   PMID:31644426   PMID:31653894  
PMID:31665636   PMID:31694960   PMID:31712393   PMID:31719183   PMID:31730616   PMID:31732720   PMID:31742873   PMID:31775040   PMID:31784108   PMID:31825972   PMID:31826984   PMID:31831806  
PMID:31877196   PMID:31883840   PMID:31896593   PMID:31900342   PMID:31937766   PMID:31959883   PMID:31968247   PMID:31972159   PMID:31980536   PMID:32044112   PMID:32057291   PMID:32075762  
PMID:32101732   PMID:32150572   PMID:32187540   PMID:32204792   PMID:32213589   PMID:32242005   PMID:32269339   PMID:32270034   PMID:32348763   PMID:32373120   PMID:32404939   PMID:32433975  
PMID:32444775   PMID:32516576   PMID:32522837   PMID:32544190   PMID:32553163   PMID:32553167   PMID:32553273   PMID:32560903   PMID:32581235   PMID:32629384   PMID:32641828   PMID:32643603  
PMID:32663191   PMID:32690888   PMID:32727588   PMID:32732870   PMID:32750141   PMID:32807917   PMID:32840576   PMID:32929218   PMID:33042133   PMID:33087405   PMID:33125891   PMID:33147451  
PMID:33165593   PMID:33203860   PMID:33212011   PMID:33257540   PMID:33261178   PMID:33298616   PMID:33315931   PMID:33338425   PMID:33373293   PMID:33469015   PMID:33479228   PMID:33510463  
PMID:33688034  


Genomics

Comparative Map Data
Ifnar1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,281,016 - 91,307,411 (+)NCBIGRCm39mm39
GRCm39 Ensembl1691,282,126 - 91,304,329 (+)Ensembl
GRCm381691,485,032 - 91,510,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,485,238 - 91,507,441 (+)EnsemblGRCm38mm10GRCm38
MGSCv371691,485,460 - 91,510,768 (+)NCBIGRCm37mm9NCBIm37
MGSCv361691,374,108 - 91,396,296 (+)NCBImm8
Celera1692,562,831 - 92,587,086 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1652.98NCBI
IFNAR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2133,324,429 - 33,359,864 (+)EnsemblGRCh38hg38GRCh38
GRCh382133,324,395 - 33,359,864 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372134,696,700 - 34,732,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,619,084 - 33,653,999 (+)NCBINCBI36hg18NCBI36
Build 342133,619,083 - 33,653,996NCBI
Celera2119,887,300 - 19,922,214 (+)NCBI
Cytogenetic Map21q22.11ENTREZGENE
HuRef2120,166,044 - 20,200,958 (+)NCBIHuRef
CHM1_12134,259,582 - 34,294,500 (+)NCBICHM1_1
Ifnar1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21130,725,774 - 30,752,227 (+)NCBI
Rnor_6.0 Ensembl1131,640,407 - 31,664,061 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01131,640,407 - 31,666,839 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01135,248,575 - 35,272,235 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,454,789 - 31,478,449 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11131,494,121 - 31,518,864 (+)NCBI
Celera1130,393,241 - 30,416,960 (+)NCBICelera
Cytogenetic Map11q11NCBI
Ifnar1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540732,730,953 - 32,754,651 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540732,730,973 - 32,755,404 (+)NCBIChiLan1.0ChiLan1.0
IFNAR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12133,058,410 - 33,093,824 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2133,058,396 - 33,093,824 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02119,683,496 - 19,719,034 (+)NCBIMhudiblu_PPA_v0panPan3
IFNAR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13128,854,765 - 28,876,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3127,950,128 - 27,972,344 (+)NCBI
ROS_Cfam_1.03128,160,372 - 28,182,033 (+)NCBI
UMICH_Zoey_3.13128,027,680 - 28,049,300 (+)NCBI
UNSW_CanFamBas_1.03128,037,690 - 28,059,324 (+)NCBI
UU_Cfam_GSD_1.03128,540,987 - 28,562,614 (+)NCBI
Ifnar1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497128,493,890 - 28,514,014 (+)NCBI
SpeTri2.0NW_0049365008,953,809 - 8,975,261 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFNAR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13196,925,704 - 196,952,239 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113196,925,731 - 196,951,398 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IFNAR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,824,600 - 58,854,519 (-)NCBI
ChlSab1.1 Ensembl258,825,916 - 58,854,568 (-)Ensembl
Vero_WHO_p1.0NW_0236660711,327,549 - 1,360,671 (-)NCBI
Ifnar1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474521,545,846 - 21,569,719 (+)NCBI

Position Markers
px-65a8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A1UniSTS
Cytogenetic Map8B1.2UniSTS
Cytogenetic Map1H2.3-H3UniSTS
Cytogenetic Map17B3UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map3G1UniSTS
px-72g5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7CUniSTS
Cytogenetic Map3H2UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map3G1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map12B1UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic Map8B1.2UniSTS
Cytogenetic Map9A1UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map3BUniSTS
cM Map1354.0UniSTS
cM Map91.0UniSTS
cM Map316.4UniSTS
Ifnar1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C3.3UniSTS
cM Map1663.2UniSTS
px-24g4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7CUniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map3H2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map3F2.3UniSTS
Cytogenetic Map3G1UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map12B1UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map15A1UniSTS
Cytogenetic Map16C3.3UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map9A1UniSTS
Cytogenetic Map17E2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map17CUniSTS
cM Map91.0UniSTS
cM Map316.4UniSTS
cM Map1740.0UniSTS
cM Map1354.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163562627392776120Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166181175695811876Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6318975897189758Mouse
1300928Etia_methanol induced activation (mouse)Not determined166351701997517128Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166353044897530584Mouse
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166880383498207768Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166927924498207768Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166933072398207768Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166933072398207768Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166933072398207768Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166945759498207768Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167058336498207768Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1744
Count of miRNA genes:560
Interacting mature miRNAs:649
Transcripts:ENSMUST00000023689, ENSMUST00000117748, ENSMUST00000123196, ENSMUST00000129878, ENSMUST00000145008
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_384931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC132272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC150035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE955685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA322032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M89641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000023689   ⟹   ENSMUSP00000023689
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,485,238 - 91,507,441 (+)Ensembl
RefSeq Acc Id: ENSMUST00000117748   ⟹   ENSMUSP00000112670
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,485,264 - 91,507,441 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123196   ⟹   ENSMUSP00000119160
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,485,249 - 91,507,437 (+)Ensembl
RefSeq Acc Id: ENSMUST00000129878   ⟹   ENSMUSP00000120945
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,485,336 - 91,496,174 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145008
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,485,277 - 91,491,789 (+)Ensembl
RefSeq Acc Id: ENSMUST00000231604
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,492,649 - 91,499,480 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232453   ⟹   ENSMUSP00000156150
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,505,304 - 91,506,666 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232509   ⟹   ENSMUSP00000156101
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1691,485,316 - 91,496,173 (+)Ensembl
RefSeq Acc Id: NM_010508   ⟹   NP_034638
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391691,282,103 - 91,307,411 (+)NCBI
GRCm381691,485,215 - 91,510,523 (+)NCBI
MGSCv371691,485,460 - 91,510,768 (+)RGD
Celera1692,562,831 - 92,587,086 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_384931
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391691,281,016 - 91,307,411 (+)NCBI
GRCm381691,485,032 - 91,507,438 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034638   ⟸   NM_010508
- Peptide Label: precursor
- UniProtKB: P33896 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000120945   ⟸   ENSMUST00000129878
RefSeq Acc Id: ENSMUSP00000156150   ⟸   ENSMUST00000232453
RefSeq Acc Id: ENSMUSP00000156101   ⟸   ENSMUST00000232509
RefSeq Acc Id: ENSMUSP00000119160   ⟸   ENSMUST00000123196
RefSeq Acc Id: ENSMUSP00000112670   ⟸   ENSMUST00000117748
RefSeq Acc Id: ENSMUSP00000023689   ⟸   ENSMUST00000023689
Protein Domains
Fibronectin type-III   Interfer-bind

Promoters
RGD ID:6827141
Promoter ID:MM_KWN:21697
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_010508,   OTTMUST00000067226,   OTTMUST00000067227,   OTTMUST00000085103,   UC007ZXO.1,   UC007ZXP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361691,485,086 - 91,485,707 (+)MPROMDB
RGD ID:13674436
Promoter ID:EPDNEW_M21367
Type:initiation region
Name:Ifnar1_1
Description:Mus musculus interferon receptor 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381691,485,246 - 91,485,306EPDNEW
RGD ID:6847310
Promoter ID:MM_ACW:21232
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:IFNAR1.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361691,505,791 - 91,506,291 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:107658 AgrOrtholog
Ensembl Genes ENSMUSG00000022967 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023689 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000112670 UniProtKB/Swiss-Prot
  ENSMUSP00000119160 UniProtKB/TrEMBL
  ENSMUSP00000120945 UniProtKB/TrEMBL
  ENSMUSP00000156101 UniProtKB/TrEMBL
  ENSMUSP00000156150 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023689 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000117748 UniProtKB/Swiss-Prot
  ENSMUST00000123196 UniProtKB/TrEMBL
  ENSMUST00000129878 UniProtKB/TrEMBL
  ENSMUST00000232453 UniProtKB/TrEMBL
  ENSMUST00000232509 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon/interleukin_rcp_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon_alpha/beta_rcpt-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15975 UniProtKB/Swiss-Prot
MGD MGI:107658 ENTREZGENE
NCBI Gene 15975 ENTREZGENE
Pfam Interfer-bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tissue_fac UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IFNAR1 RGD
PhenoGen Ifnar1 PhenoGen
PIRSF IFN_alpha/beta_recept-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A338P6T9_MOUSE UniProtKB/TrEMBL
  A0A338P6X7_MOUSE UniProtKB/TrEMBL
  A0A384DVB8_MOUSE UniProtKB/TrEMBL
  A0A5P8D1R0_MOUSE UniProtKB/TrEMBL
  E9PWM1_MOUSE UniProtKB/TrEMBL
  INAR1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U5G8_MOUSE UniProtKB/TrEMBL
  Q3UFX4_MOUSE UniProtKB/TrEMBL
  Q80UR8_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q80UJ3 UniProtKB/Swiss-Prot