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Gene: Rasgrf1 (RAS protein-specific guanine nucleotide-releasing factor 1) Mus musculus
Symbol: Rasgrf1
Name: RAS protein-specific guanine nucleotide-releasing factor 1
Description: Exhibits glutamate receptor binding activity. Involved in several processes, including activation of GTPase activity; regulation of neuronal synaptic plasticity; and regulation of signal transduction. Localizes to the cytosol and growth cone. Is expressed in several structures, including alimentary system; face; genitourinary system; nervous system; and sensory organ. Orthologous to human RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI844718; CDC25; CDC25Mm; expressed sequence AI844718; Gnrp; GRF beta; Grf1; Grfbeta; guanine nucleotide releasing factor 1; guanine nucleotide-releasing protein; p190; P190-A; p190RhoGEF; Ras guanine release factor beta; Ras-GRF1; ras-specific guanine nucleotide-releasing factor 1; ras-specific nucleotide exchange factor CDC25
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38989,909,508 - 90,026,979 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37989,804,613 - 89,921,817 (+)NCBIGRCm37mm9NCBIm37
MGSCv36989,707,668 - 89,827,694 (+)NCBImm8
Celera989,525,851 - 89,642,271 (+)NCBICelera
Cytogenetic Map9 E3.1NCBI
cM Map947.31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rasgrf1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551710
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.