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Gene: Cul2 (cullin 2) Mus musculus
Symbol: Cul2
Name: cullin 2
Description: Predicted to have ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Involved in protein catabolic process. Localizes to Cul2-RING ubiquitin ligase complex and nucleolus. Is expressed in cervical ganglion; cervico-thoracic ganglion; dorsal root ganglion; thoracic ganglion; and trigeminal ganglion. Orthologous to human CUL2 (cullin 2); PARTICIPATES IN hypoxia inducible factor pathway; neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300003D18Rik; 4932411N15Rik; AI327301; CUL-2; cullin-2; KIAA4106; mKIAA4106
Homo sapiens (human) : CUL2 (cullin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cul2 (cullin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul2 (cullin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL2 (cullin 2)
Canis lupus familiaris (dog) : CUL2 (cullin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul2 (cullin 2)
Sus scrofa (pig) : CUL2 (cullin 2)
Chlorocebus sabaeus (African green monkey) : CUL2 (cullin 2)
Heterocephalus glaber (naked mole-rat) : Cul2 (cullin 2)
more info ...
Related Pseudogenes: Gm4855  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl183,382,988 - 3,436,377 (+)EnsemblGRCm38mm10GRCm38
GRCm38183,382,970 - 3,436,700 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37183,383,223 - 3,436,698 (+)NCBIGRCm37mm9NCBIm37
MGSCv36183,383,029 - 3,436,372 (+)NCBImm8
Celera183,432,713 - 3,487,378 (+)NCBICelera
Cytogenetic Map18A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cul2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321671
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.