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Gene: Cul2 (cullin 2) Mus musculus
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Symbol: Cul2
Name: cullin 2
Description: Predicted to have ubiquitin protein ligase binding activity and ubiquitin-protein transferase activity. Involved in protein catabolic process. Localizes to Cul2-RING ubiquitin ligase complex and nucleolus. Is expressed in cervical ganglion; cervico-thoracic ganglion; dorsal root ganglion; thoracic ganglion; and trigeminal ganglion. Orthologous to human CUL2 (cullin 2); PARTICIPATES IN hypoxia inducible factor pathway; neddylation pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300003D18Rik; 4932411N15Rik; AI327301; CUL-2; cullin-2; KIAA4106; mKIAA4106
Orthologs:
Homo sapiens (human) : CUL2 (cullin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cul2 (cullin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cul2 (cullin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CUL2 (cullin 2)
Canis lupus familiaris (dog) : CUL2 (cullin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cul2 (cullin 2)
Sus scrofa (pig) : CUL2 (cullin 2)
Chlorocebus sabaeus (African green monkey) : CUL2 (cullin 2)
Heterocephalus glaber (naked mole-rat) : Cul2 (cullin 2)
more info ...
Related Pseudogenes: Gm4855  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl183,382,988 - 3,436,377 (+)EnsemblGRCm38mm10GRCm38
GRCm38183,382,970 - 3,436,700 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37183,383,223 - 3,436,698 (+)NCBIGRCm37mm9NCBIm37
MGSCv36183,383,029 - 3,436,372 (+)NCBImm8
Celera183,432,713 - 3,487,378 (+)NCBICelera
Cytogenetic Map18A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cul2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321671
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.