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Gene: Dctn2 (dynactin 2) Mus musculus
Symbol: Dctn2
Name: dynactin 2
Description: Predicted to have identical protein binding activity; protein kinase binding activity; and spectrin binding activity. Involved in melanosome transport. Localizes to growth cone. Is expressed in several structures, including adipose tissue; alimentary system; early conceptus; genitourinary system; and nervous system. Orthologous to human DCTN2 (dynactin subunit 2); PARTICIPATES IN mitochondria transport pathway; Huntington's disease pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310042E05Rik; 50 kDa dynein-associated polypeptide; C130077D06Rik; C87049; DCTN-5; DCTN-50; dynactin complex 50 kDa subunit; dynactin subunit 2; GMP23-48K; growth cone membrane protein 23-48K; p5; p50; p50 dynamitin; RBP; RBP50
Homo sapiens (human) : DCTN2 (dynactin subunit 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dctn2 (dynactin subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dctn2 (dynactin subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DCTN2 (dynactin subunit 2)
Canis lupus familiaris (dog) : DCTN2 (dynactin subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dctn2 (dynactin subunit 2)
Sus scrofa (pig) : DCTN2 (dynactin subunit 2)
Chlorocebus sabaeus (African green monkey) : DCTN2 (dynactin subunit 2)
Heterocephalus glaber (naked mole-rat) : Dctn2 (dynactin subunit 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl10127,266,368 - 127,281,950 (+)EnsemblGRCm38mm10GRCm38
GRCm3810127,266,262 - 127,281,959 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,703,318 - 126,719,015 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610126,669,348 - 126,684,756 (+)NCBImm8
Celera10129,658,775 - 129,674,400 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dctn2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553080
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.