Tgoln1 (trans-golgi network protein) - Rat Genome Database
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Gene: Tgoln1 (trans-golgi network protein) Mus musculus
Analyze
Symbol: Tgoln1
Name: trans-golgi network protein
RGD ID: 1624067
MGI Page MGI
Description: Localizes to endosome and trans-Golgi network. Is expressed in dorsal root ganglion. Orthologous to human TGOLN2 (trans-golgi network protein 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU015504; D6Ertd384; D6Ertd384e; TGN3; TGN38; TGN38A; trans-Golgi network integral membrane protein 1; trans-golgi network protein 1; Ttgn; Ttgn1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,585,403 - 72,593,983 (-)NCBIGRCm39mm39
GRCm38672,608,420 - 72,617,000 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,608,432 - 72,617,000 (-)EnsemblGRCm38mm10GRCm38
MGSCv37672,558,414 - 72,566,994 (-)NCBIGRCm37mm9NCBIm37
MGSCv36672,537,929 - 72,546,509 (-)NCBImm8
Celera674,706,688 - 74,717,943 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (ISO)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (EXP)
chloroquine  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dimethoate  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzacamene  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
finasteride  (ISO)
fluoranthene  (EXP)
flurbiprofen  (EXP)
folic acid  (EXP)
gentamycin  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
Methylazoxymethanol acetate  (ISO)
nickel sulfate  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
pyrogallol  (EXP)
rotenone  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium fluoride  (EXP)
tamibarotene  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP)
titanium dioxide  (EXP)
torcetrapib  (ISO)
troglitazone  (EXP)
uranium atom  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7540170   PMID:7642711   PMID:8889548   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12488345  
PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16204232   PMID:16369483   PMID:16778019   PMID:18166528   PMID:18434600   PMID:18662990   PMID:19838196   PMID:20230794  
PMID:21187406   PMID:21267068   PMID:21873635   PMID:22841714   PMID:25486359   PMID:26582200   PMID:27655914   PMID:31487503  


Genomics

Comparative Map Data
Tgoln1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39672,585,403 - 72,593,983 (-)NCBIGRCm39mm39
GRCm38672,608,420 - 72,617,000 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl672,608,432 - 72,617,000 (-)EnsemblGRCm38mm10GRCm38
MGSCv37672,558,414 - 72,566,994 (-)NCBIGRCm37mm9NCBIm37
MGSCv36672,537,929 - 72,546,509 (-)NCBImm8
Celera674,706,688 - 74,717,943 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.27NCBI
TGOLN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl285,318,020 - 85,328,296 (-)EnsemblGRCh38hg38GRCh38
GRCh38285,318,027 - 85,327,989 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37285,545,150 - 85,555,112 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37285,545,141 - 85,555,419 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36285,398,657 - 85,408,885 (-)NCBINCBI36hg18NCBI36
Build 34285,456,804 - 85,467,032NCBI
Celera285,373,190 - 85,383,374 (-)NCBI
Cytogenetic Map2p11.2NCBI
HuRef285,442,101 - 85,452,375 (-)NCBIHuRef
CHM1_1285,474,875 - 85,485,153 (-)NCBICHM1_1
Tgoln2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24104,663,356 - 104,671,208 (-)NCBI
Rnor_6.0 Ensembl4100,475,416 - 100,483,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04100,475,415 - 100,483,229 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04165,245,798 - 165,253,551 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44106,110,153 - 106,117,906 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14106,356,599 - 106,362,385 (-)NCBI
Celera493,816,266 - 93,824,018 (-)NCBICelera
Cytogenetic Map4q31NCBI
Tgoln2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554242,122,410 - 2,131,734 (-)NCBIChiLan1.0ChiLan1.0
TGOLN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A86,922,492 - 86,932,902 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v02A85,370,686 - 85,381,607 (-)NCBIMhudiblu_PPA_v0panPan3
TGOLN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11739,681,362 - 39,690,828 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tgoln2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367121,837,235 - 1,845,482 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGOLN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1359,416,681 - 59,426,790 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2362,299,087 - 62,303,473 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGOLN2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11421,828,106 - 21,854,074 (+)NCBI
ChlSab1.1 Ensembl1421,828,194 - 21,835,243 (+)Ensembl
Tgoln2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474917,787,165 - 17,797,328 (-)NCBI

Position Markers
BE335351  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,611,542 - 72,611,631UniSTSGRCm38
MGSCv37672,561,536 - 72,561,625UniSTSGRCm37
Celera674,709,810 - 74,709,899UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6724.33UniSTS
AU015504  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,610,639 - 72,610,758UniSTSGRCm38
MGSCv37672,560,633 - 72,560,752UniSTSGRCm37
Celera674,708,907 - 74,709,026UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6715.8UniSTS
D50031  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,611,818 - 72,611,910UniSTSGRCm38
MGSCv37672,561,812 - 72,561,904UniSTSGRCm37
Celera674,710,088 - 74,710,180UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6718.74UniSTS
RH127112  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38672,610,476 - 72,610,680UniSTSGRCm38
MGSCv37672,560,470 - 72,560,674UniSTSGRCm37
Celera674,708,744 - 74,708,948UniSTS
Cytogenetic Map6C1UniSTS
cM Map631.5UniSTS
Whitehead/MRC_RH6721.28UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3285065078238974Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64160000075600000Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64211637376116515Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64211637376116515Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64211637376116515Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64211637376116515Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64382681377811523Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64382681377811523Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64382681377811523Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64382681377811523Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64382681377811523Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64382681377811523Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4872655675447710Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1441
Count of miRNA genes:631
Interacting mature miRNAs:816
Transcripts:ENSMUST00000070524
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC125039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC141218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D50031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ689254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000070524   ⟹   ENSMUSP00000068487
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl672,608,432 - 72,617,000 (-)Ensembl
RefSeq Acc Id: NM_009443   ⟹   NP_033469
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39672,585,403 - 72,593,983 (-)NCBI
GRCm38672,608,420 - 72,617,000 (-)ENTREZGENE
MGSCv37672,558,414 - 72,566,994 (-)RGD
Celera674,706,688 - 74,717,943 (-)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033469   ⟸   NM_009443
- Peptide Label: precursor
- UniProtKB: Q62313 (UniProtKB/Swiss-Prot),   Q4FJY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000068487   ⟸   ENSMUST00000070524

Promoters
RGD ID:6840082
Promoter ID:MM_KWN:46478
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000070524,   NM_009444_TGOLN2_NOT_IN_BL6,   UC009CIY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36672,566,681 - 72,567,622 (-)MPROMDB
RGD ID:6890034
Promoter ID:EPDNEW_M8468
Type:initiation region
Name:Tgoln1_1
Description:Mus musculus trans-golgi network protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38672,616,747 - 72,616,807EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105080 AgrOrtholog
Ensembl Genes ENSMUSG00000056429 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000068487 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000070524 ENTREZGENE, UniProtKB/Swiss-Prot
KEGG Report mmu:22134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:105080 ENTREZGENE
NCBI Gene 22134 ENTREZGENE
PhenoGen Tgoln1 PhenoGen
UniProt Q4FJY3 ENTREZGENE, UniProtKB/TrEMBL
  Q62313 ENTREZGENE, UniProtKB/Swiss-Prot