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Gene: Dnm1l (dynamin 1-like) Mus musculus
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Symbol: Dnm1l
Name: dynamin 1-like
Description: Exhibits protein homodimerization activity. Involved in several processes, including necroptotic process; regulation of organelle organization; and regulation of ubiquitin protein ligase activity. Localizes to several cellular components, including the brush border; microtubule cytoskeleton; and mitochondrial outer membrane. Predicted to colocalize with the clathrin-coated pit; mitochondrial membrane; and mitochondrion-derived vesicle. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in brain disease and optic atrophy. Is expressed in heart. Orthologous to human DNM1L (dynamin 1 like).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6330417M19Rik; AI450666; Dlp1; Dnmlp1; Drp1; dymple; dynamin family member proline-rich carboxyl-terminal domain less; dynamin-1-like protein; dynamin-like protein 1; dynamin-related protein 1; MGC90593; python
Orthologs:
Homo sapiens (human) : DNM1L (dynamin 1 like)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnm1l (dynamin 1-like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnm1l (dynamin 1 like)
Pan paniscus (bonobo/pygmy chimpanzee) : DNM1L (dynamin 1 like)
Canis lupus familiaris (dog) : DNM1L (dynamin 1 like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnm1l (dynamin 1 like)
Sus scrofa (pig) : DNM1L (dynamin 1 like)
Chlorocebus sabaeus (African green monkey) : DNM1L (dynamin 1 like)
Heterocephalus glaber (naked mole-rat) : Dnm1l (dynamin 1 like)
more info ...
Related Pseudogenes: Gm13719  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1616,312,230 - 16,358,959 (-)Ensembl
GRCm381616,312,228 - 16,359,038 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371616,312,326 - 16,359,123 (-)NCBIGRCm37mm9NCBIm37
MGSCv361616,225,811 - 16,272,608 (-)NCBImm8
Celera1616,883,269 - 16,930,065 (-)NCBICelera
Cytogenetic Map16A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dnm1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733619
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.