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Gene: Dnm1l (dynamin 1-like) Mus musculus
Symbol: Dnm1l
Name: dynamin 1-like
Description: Exhibits protein homodimerization activity. Involved in several processes, including necroptotic process; regulation of organelle organization; and regulation of ubiquitin protein ligase activity. Localizes to several cellular components, including the brush border; microtubule cytoskeleton; and mitochondrial outer membrane. Predicted to colocalize with the clathrin-coated pit; mitochondrial membrane; and mitochondrion-derived vesicle. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in brain disease and optic atrophy. Is expressed in heart. Orthologous to human DNM1L (dynamin 1 like).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 6330417M19Rik; AI450666; Dlp1; Dnmlp1; Drp1; dymple; dynamin family member proline-rich carboxyl-terminal domain less; dynamin-1-like protein; dynamin-like protein 1; dynamin-related protein 1; MGC90593; python
Homo sapiens (human) : DNM1L (dynamin 1 like)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnm1l (dynamin 1-like)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnm1l (dynamin 1 like)
Pan paniscus (bonobo/pygmy chimpanzee) : DNM1L (dynamin 1 like)
Canis lupus familiaris (dog) : DNM1L (dynamin 1 like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnm1l (dynamin 1 like)
Sus scrofa (pig) : DNM1L (dynamin 1 like)
Chlorocebus sabaeus (African green monkey) : DNM1L (dynamin 1 like)
Heterocephalus glaber (naked mole-rat) : Dnm1l (dynamin 1 like)
more info ...
Related Pseudogenes: Gm13719  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1616,312,230 - 16,358,959 (-)Ensembl
GRCm381616,312,228 - 16,359,038 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371616,312,326 - 16,359,123 (-)NCBIGRCm37mm9NCBIm37
MGSCv361616,225,811 - 16,272,608 (-)NCBImm8
Celera1616,883,269 - 16,930,065 (-)NCBICelera
Cytogenetic Map16A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dnm1l
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733619
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.