Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in increased expression of SLC16A11 mRNA | CTD | PMID:27840820 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of SLC16A11 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SLC16A11 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in decreased expression of SLC16A11 mRNA | CTD | PMID:17557909 | 17beta-estradiol | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of SLC16A11 mRNA | CTD | PMID:32145629 | 2,2',5,5'-tetrachlorobiphenyl | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC16A11 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SLC16A11 mRNA | CTD | PMID:33387578 | 2,6-dinitrotoluene | affects expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of SLC16A11 mRNA | CTD | PMID:21346803 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SLC16A11 mRNA | CTD | PMID:36041667 | 6-propyl-2-thiouracil | affects expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Propylthiouracil affects the expression of SLC16A11 mRNA | CTD | PMID:24780913 | amiodarone | increases expression | EXP | | 6480464 | Amiodarone results in increased expression of SLC16A11 mRNA | CTD | PMID:24535564 | aristolochic acid A | increases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SLC16A11 mRNA | CTD | PMID:33212167 | Aroclor 1254 | increases expression | EXP | | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of SLC16A11 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SLC16A11 mRNA | CTD | PMID:25908611 | benzo[a]pyrene | affects methylation | ISO | SLC16A11 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC16A11 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of SLC16A11 mRNA | CTD | PMID:26377693 | bisphenol A | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SLC16A11 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SLC16A11 mRNA | CTD | PMID:36041667 | bisphenol A | increases methylation | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of SLC16A11 gene | CTD | PMID:28505145 | bisphenol A | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SLC16A11 mRNA | CTD | PMID:30816183 and PMID:34947998 | bisphenol F | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of SLC16A11 mRNA | CTD | PMID:36041667 | cadmium atom | decreases expression | EXP | | 6480464 | Cadmium results in decreased expression of SLC16A11 mRNA | CTD | PMID:24067728 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | chlorohydrocarbon | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of SLC16A11 mRNA | CTD | PMID:30744511 | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of SLC16A11 mRNA | CTD | PMID:29279043 | Cuprizon | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of SLC16A11 mRNA | CTD | PMID:27523638 | dichloroacetic acid | increases expression | EXP | | 6480464 | Dichloroacetic Acid results in increased expression of SLC16A11 mRNA | CTD | PMID:28962523 | dieldrin | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Dieldrin results in decreased expression of SLC16A11 mRNA | CTD | PMID:23153324 | disodium selenite | increases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SLC16A11 mRNA | CTD | PMID:18175754 | endosulfan | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of SLC16A11 mRNA | CTD | PMID:29391264 | fenthion | increases expression | EXP | | 6480464 | Fenthion results in increased expression of SLC16A11 mRNA | CTD | PMID:34813904 | fipronil | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | fipronil results in decreased expression of SLC16A11 mRNA | CTD | PMID:23962444 | flutamide | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of SLC16A11 mRNA | CTD | PMID:21525395 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of SLC16A11 mRNA] | CTD | PMID:22206623 | fonofos | increases methylation | ISO | SLC16A11 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of SLC16A11 promoter | CTD | PMID:22847954 | furan | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | furan results in decreased expression of SLC16A11 mRNA | CTD | PMID:26194646 | Genipin | multiple interactions | EXP | | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SLC16A11 mRNA] | CTD | PMID:22687549 | gentamycin | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of SLC16A11 mRNA | CTD | PMID:33387578 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SLC16A11 mRNA | CTD | PMID:36331819 | iron dichloride | decreases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of SLC16A11 mRNA | CTD | PMID:35984750 | Licochalcone B | increases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of SLC16A11 mRNA | CTD | PMID:33647349 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | genipin inhibits the reaction [Lipopolysaccharides results in increased expression of SLC16A11 mRNA] | CTD | PMID:22687549 | lipopolysaccharide | increases expression | EXP | | 6480464 | Lipopolysaccharides results in increased expression of SLC16A11 mRNA | CTD | PMID:22687549 | manganese(II) chloride | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | manganese chloride results in increased expression of SLC16A11 mRNA | CTD | PMID:28801915 | methamphetamine | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Methamphetamine results in decreased expression of SLC16A11 mRNA | CTD | PMID:19564919 | methamphetamine | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A11 mRNA | CTD | PMID:19564919 | methylmercury chloride | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in decreased expression of SLC16A11 mRNA | CTD | PMID:30744511 | N-nitrosodiethylamine | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of SLC16A11 mRNA | CTD | PMID:28943392 | N-Nitrosopyrrolidine | decreases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | N-Nitrosopyrrolidine results in decreased expression of SLC16A11 mRNA | CTD | PMID:32234424 | orphenadrine | affects expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Orphenadrine affects the expression of SLC16A11 mRNA | CTD | PMID:23665939 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of SLC16A11 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SLC16A11 mRNA | CTD | PMID:17562736 | paracetamol | affects expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Acetaminophen affects the expression of SLC16A11 mRNA | CTD | PMID:33387578 | parathion | increases methylation | ISO | SLC16A11 (Homo sapiens) | 6480464 | Parathion results in increased methylation of SLC16A11 promoter | CTD | PMID:22847954 | PCB138 | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:23829299 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of SLC16A11 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of SLC16A11 mRNA | CTD | PMID:36331819 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of SLC16A11 mRNA | CTD | PMID:18301758 and PMID:23811191 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of SLC16A11 mRNA | CTD | PMID:28903501 | pyrazinecarboxamide | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Pyrazinamide results in decreased expression of SLC16A11 mRNA | CTD | PMID:22431067 | resveratrol | multiple interactions | ISO | SLC16A11 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SLC16A11 mRNA | CTD | PMID:23557933 | SCH 23390 | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A11 mRNA | CTD | PMID:19564919 | SCH 23390 | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | SCH 23390 results in decreased expression of SLC16A11 mRNA | CTD | PMID:19564919 | silicon dioxide | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Silicon Dioxide results in increased expression of SLC16A11 mRNA | CTD | PMID:22431001 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of SLC16A11 mRNA | CTD | PMID:37682722 | tebuconazole | decreases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | tebuconazole results in decreased expression of SLC16A11 mRNA | CTD | PMID:30458266 | terbufos | increases methylation | ISO | SLC16A11 (Homo sapiens) | 6480464 | terbufos results in increased methylation of SLC16A11 promoter | CTD | PMID:22847954 | testosterone | multiple interactions | EXP | | 6480464 | 1 more ... | CTD | PMID:33848595 | testosterone | increases expression | EXP | | 6480464 | Testosterone deficiency results in increased expression of SLC16A11 mRNA | CTD | PMID:33848595 | thioacetamide | multiple interactions | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of SLC16A11 mRNA | CTD | PMID:28943392 | thioacetamide | decreases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of SLC16A11 mRNA | CTD | PMID:34492290 | titanium dioxide | affects expression | EXP | | 6480464 | titanium dioxide affects the expression of SLC16A11 mRNA | CTD | PMID:23557971 | titanium dioxide | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | titanium dioxide results in increased expression of SLC16A11 mRNA | CTD | PMID:30012374 | trichloroethene | increases methylation | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of SLC16A11 gene | CTD | PMID:27618143 | trichloroethene | increases expression | ISO | Slc16a11 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of SLC16A11 mRNA | CTD | PMID:33387578 | triclosan | increases methylation | ISO | SLC16A11 (Homo sapiens) | 6480464 | Triclosan results in increased methylation of SLC16A11 gene | CTD | PMID:34523531 | urethane | increases expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | Urethane results in increased expression of SLC16A11 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of SLC16A11 mRNA | CTD | PMID:24535564 | valproic acid | affects expression | ISO | SLC16A11 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SLC16A11 mRNA | CTD | PMID:25979313 | |