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Gene: Nrxn1 (neurexin I) Mus musculus
Symbol: Nrxn1
Name: neurexin I
Description: Exhibits several functions, including calcium channel regulator activity; calcium-dependent protein binding activity; and signaling receptor binding activity. Involved in several processes, including regulation of glutamate receptor signaling pathway; regulation of synapse organization; and synapse organization. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; axonal growth cone; and integral component of presynaptic active zone membrane. Predicted to colocalize with slit diaphragm. Is expressed in several structures, including adrenal gland; limb; nervous system; oral epithelium; and sensory organ. Used to study autism spectrum disorder and schizophrenia. Human ortholog(s) of this gene implicated in Pitt-Hopkins-like syndrome 2. Orthologous to human NRXN1 (neurexin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1700062G21Rik; 9330127H16Rik; A230068P09Rik; alpha-latrotoxin receptor (calcium-dependent); mKIAA0578; neurexin 1 NRXN1+7a; neurexin 1 NRXN1-7; neurexin I alpha; neurexin I beta; neurexin I-alpha; Neurexin I-beta; neurexin-1; neurexin-1-alpha; Neurexin-1-beta
Homo sapiens (human) : NRXN1 (neurexin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nrxn1 (neurexin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrxn1 (neurexin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NRXN1 (neurexin 1)
Canis lupus familiaris (dog) : NRXN1 (neurexin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrxn1 (neurexin 1)
Sus scrofa (pig) : NRXN1 (neurexin 1)
Chlorocebus sabaeus (African green monkey) : NRXN1 (neurexin 1)
Heterocephalus glaber (naked mole-rat) : Nrxn1 (neurexin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1790,033,631 - 91,093,071 (-)EnsemblGRCm38mm10GRCm38
GRCm381790,033,644 - 91,093,159 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371790,432,984 - 91,492,142 (-)NCBIGRCm37mm9NCBIm37
MGSCv361790,433,296 - 91,492,142 (-)NCBImm8
Celera1794,417,402 - 95,489,954 (-)NCBICelera
Cytogenetic Map17E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links