Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gfap (glial fibrillary acidic protein) Mus musculus
Symbol: Gfap
Name: glial fibrillary acidic protein
Description: A structural constituent of cytoskeleton. Involved in several processes, including intermediate filament organization; long-term synaptic potentiation; and neurogenesis. Localizes to several cellular components, including astrocyte end-foot; cell body; and intermediate filament. Is expressed in several structures, including alimentary system; hemolymphoid system; integumental system; nervous system; and sensory organ. Used to study Alexander disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein); PARTICIPATES IN chaperone mediated autophagy pathway; INTERACTS WITH (R)-lipoic acid; (S)-amphetamine; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI836096; intermediate filament protein
Homo sapiens (human) : GFAP (glial fibrillary acidic protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gfap (glial fibrillary acidic protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfap (glial fibrillary acidic protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GFAP (glial fibrillary acidic protein)
Canis lupus familiaris (dog) : GFAP (glial fibrillary acidic protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfap (glial fibrillary acidic protein)
Sus scrofa (pig) : GFAP (glial fibrillary acidic protein)
Chlorocebus sabaeus (African green monkey) : GFAP (glial fibrillary acidic protein)
Heterocephalus glaber (naked mole-rat) : Gfap (glial fibrillary acidic protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11102,887,336 - 102,900,912 (-)EnsemblGRCm38mm10GRCm38
GRCm3811102,887,336 - 102,897,200 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711102,748,650 - 102,758,514 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611102,704,767 - 102,713,221 (-)NCBImm8
Celera11114,598,382 - 114,608,239 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gfap
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10633
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.