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Gene: Gfap (glial fibrillary acidic protein) Mus musculus
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Symbol: Gfap
Name: glial fibrillary acidic protein
Description: A structural constituent of cytoskeleton. Involved in several processes, including intermediate filament organization; long-term synaptic potentiation; and neurogenesis. Localizes to several cellular components, including astrocyte end-foot; cell body; and intermediate filament. Is expressed in several structures, including alimentary system; hemolymphoid system; integumental system; nervous system; and sensory organ. Used to study Alexander disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein); PARTICIPATES IN chaperone mediated autophagy pathway; INTERACTS WITH (R)-lipoic acid; (S)-amphetamine; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI836096; intermediate filament protein
Orthologs:
Homo sapiens (human) : GFAP (glial fibrillary acidic protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gfap (glial fibrillary acidic protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfap (glial fibrillary acidic protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GFAP (glial fibrillary acidic protein)
Canis lupus familiaris (dog) : GFAP (glial fibrillary acidic protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfap (glial fibrillary acidic protein)
Sus scrofa (pig) : GFAP (glial fibrillary acidic protein)
Chlorocebus sabaeus (African green monkey) : GFAP (glial fibrillary acidic protein)
Heterocephalus glaber (naked mole-rat) : Gfap (glial fibrillary acidic protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl11102,887,336 - 102,900,912 (-)EnsemblGRCm38mm10GRCm38
GRCm3811102,887,336 - 102,897,200 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711102,748,650 - 102,758,514 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611102,704,767 - 102,713,221 (-)NCBImm8
Celera11114,598,382 - 114,608,239 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gfap
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10633
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.